宽胸组合物在制备用于治疗、预防或改善动脉中膜钙化药物中的应用
The chest-widening composition intervenes in the calcification signaling pathway by regulating the osteogenic phenotype transformation of vascular smooth muscle cells, solving the problem of multi-target pathological mechanism regulation of arterial media calcification in existing technologies, and achieving safe and effective delay of the process of arterial media calcification, providing a new treatment and prevention method.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- ZHEJIANG SUKEAN PHARMACEUTICAL CO LTD
- Filing Date
- 2026-03-23
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies are unable to effectively regulate the multi-target pathological mechanisms of arterial medial calcification, resulting in limited improvement in patient prognosis. Furthermore, interventional treatment carries the risk of vascular injury and restenosis. Existing drugs lack specific targeting mechanisms and cannot reverse or inhibit osteogenic calcification of medial cells.
A broad-chest composition containing sandalwood oil, long pepper oil, asarum oil, galangal oil, and borneol is used. It is administered via sublingual drip to regulate the osteogenic phenotype transformation of vascular smooth muscle cells and intervene in calcification signaling pathways. It is prepared in liquid, aerosol, and other forms for the treatment and prevention of arterial medial calcification.
By regulating the osteogenic phenotype transformation of vascular smooth muscle cells, the process of arterial media calcification is slowed down, providing a safe, convenient and effective drug intervention option, which is particularly suitable for high-risk groups such as patients with advanced chronic kidney disease and diabetes.
Smart Images
Figure CN121868426B_ABST