一种双柱切换式色谱扩展系统及切换方法
The dual-column switching chromatography extension system enables coordinated operation between the main system and the extension system, solving the problem that column equilibration and detection processes cannot be performed simultaneously, thus improving chromatographic separation efficiency and equipment utilization.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- HEBEI MEDICAL UNIVERSITY
- Filing Date
- 2026-03-23
- Publication Date
- 2026-07-17
AI Technical Summary
In existing affinity chromatography systems, column equilibration and detection processes cannot be performed simultaneously, resulting in low equipment utilization, which is a significant efficiency bottleneck, especially in laboratory research and development and industrial production.
The dual-column switching chromatography extension system is adopted. Through precise valve position control of the multi-way switching valve, the main system and the extension system can be coordinated and linked, so that the two chromatographic columns can be switched between different processes and the column regeneration and equilibration operations can be performed simultaneously.
It significantly shortens the overall separation and purification cycle, improves the output per unit time of the equipment, adapts to frequent parameter adjustments in laboratories and large-scale continuous purification scenarios in industrial applications, and improves equipment utilization.
Smart Images
Figure CN121868917B_ABST