A specimen preparation and detection device for liver cancer biopsy

Abstract

The application discloses a specimen sampling and detecting device in liver cancer biopsy, and relates to the technical field of specimen sampling and detecting, which comprises a table top, the upper surface of the table top is provided with a detecting frame for detecting the specimen, the front side of the table top is provided with a conveying belt for adjusting the position of the specimen, and a heating box for drying the dyed specimen is fixedly connected above the conveying belt. The specimen sampling and detecting device in liver cancer biopsy, the intermittent warm air blower can change the air pressure in the adjusting box, when the warm air blower is turned on, the air pressure in the adjusting box increases, the spherical nozzle rotates around the air supply pipe, the direction of the gas jet is changed, and the large-scale heating treatment of the heating box is realized, when the warm air blower is turned off, the air pressure in the adjusting box decreases, under the action of the reset spring, the spherical nozzle also returns to the initial position, and the cycle is repeated, the heat distribution in the heating box is more uniform through the action of the swing mechanism, and the drying effect and efficiency of the specimen sampling are improved.

Description

Technical Field

[0001] This invention relates to the field of specimen preparation and testing technology, specifically to a specimen preparation and testing device for liver cancer biopsy. Background Technology

[0002] Cancer biopsy is an important method for obtaining liver tissue samples through puncture or surgical resection and conducting pathological examination to diagnose liver cancer and its type. It is characterized by high accuracy, minimal invasiveness, and high safety. After obtaining the liver tissue sample, the specimen needs to be prepared for pathological testing, which provides more reliable technical support for the diagnosis of liver cancer.

[0003] Prior art (Chinese Patent Publication No. CN119666511A, Announcement Date 2025-03-21) discloses a specimen preparation and testing device for liver cancer biopsy, including a device shell, a first protective door and a second protective door installed on the device shell, a multi-functional processing component installed inside the device shell, a high-efficiency detection component installed inside the device shell, a through groove opened through the device shell, a second threaded rod rotatably connected to the device shell, a mounting bracket threadedly connected to the second threaded rod, a third threaded rod rotatably connected to the mounting bracket, a mounting plate threadedly connected to the third threaded rod, and a microscope mounted on the mounting plate. This invention solves the problems of prior art specimen preparation and testing devices being unable to simultaneously perform automatic and stable staining, cleaning and drying of multiple liver tissue sections, and being unable to perform convenient and efficient pathological testing of multiple liver tissue sections.

[0004] While existing technologies can perform automated and stable staining, cleaning, and drying of multiple liver tissue sections, the drying process uses only a single method. For specimens with high water content or special texture, this single drying method may result in excessively long drying times, affecting detection efficiency, and may even affect the quality of the specimen due to uneven drying, thereby interfering with subsequent pathological test results.

[0005] Therefore, we propose a specimen preparation and testing device for liver cancer biopsy to address the problems mentioned above. Summary of the Invention

[0006] The purpose of this invention is to provide a specimen preparation and testing device for liver cancer biopsy, in order to solve the problem mentioned in the background art that the current drying operation on the market only adopts a single method. For some specimens with high moisture content or special texture, a single drying method may lead to excessive drying time, affecting the detection efficiency, and may even affect the quality of the specimen due to uneven drying, thereby interfering with the subsequent pathological test results.

[0007] To achieve the above objectives, the present invention provides the following technical solution: a specimen preparation and testing device for liver cancer biopsy, comprising a table, a testing rack for testing specimens is provided on the upper surface of the table, a conveyor belt for adjusting the position of the specimen is provided on the front side of the table, and a heating box for drying stained specimens is fixedly connected above the conveyor belt. The heating box contains a placement box for placing the prepared specimens, and a connecting plate is fixedly connected to the side of the placement box. A sliding groove is formed on the side of the heating box, and the connecting plate is slidably connected inside the sliding groove. A fitting mechanism is provided between the connecting plate and the sliding groove. The fitting mechanism rotates the heating plate contained therein by moving the connecting plate, thereby heating the bottom of the placement box. An adjustment box is fixedly connected inside the heating box, and a swing mechanism is provided on the adjustment box. The swing mechanism achieves large-area heating of the interior of the heating box by moving the contact frame contained therein.

[0008] Preferably, a threaded rod is rotatably connected to the slide groove, and the connecting plate is threadedly connected to the threaded rod, with the connecting plate and the slide groove forming a sliding structure through the threaded rod.

[0009] Preferably, the bonding mechanism includes a rotating shaft, which is rotatably connected to the lower surface of the placement box, and the two sides of the rotating shaft are fixedly connected to the heating plate. When the placement box is located above the heating box, the heating plate is set in a vertical state.

[0010] Preferably, a traction rope is wound around the outer side of the rotating shaft, and the other side of the traction rope is wound around the lower part of the connecting plate and fixedly connected to the lower side of the slide groove. Two sets of traction ropes are symmetrically arranged about the center point of the connecting plate.

[0011] Preferably, a torsion spring is fixedly connected between the middle part of the rotating shaft and the lower surface of the placement box. When the placement box is located below the heating box, the heating plate is set in a horizontal state, and the heating plate and the lower surface of the placement box are in contact with each other.

[0012] Preferably, a heater that is intermittently turned on is fixedly connected to the side of the heating box, and the output end of the heater is connected to the regulating box. A preheating groove for gas to flow out is opened at the lower inner side of the regulating box. A sealing plate is fixedly connected to the side of the placement box. When the placement box is located below the heating box, the sealing plate seals the preheating groove.

[0013] Preferably, the swing mechanism includes a piston plate, which is slidably connected inside the adjustment box, and the piston plate has ventilation holes on its side. The piston plate is located on the left and right sides of the preheating tank, and a sliding rod is fixedly connected to the middle of the piston plate.

[0014] Preferably, the slide rod is slidably connected to the side of the adjustment box, and an abutment is fixedly connected to the outer side of the slide rod, and a return spring is fixedly connected between the piston plate and the inner wall of the adjustment box.

[0015] Preferably, an air supply pipe is connected to the side of the adjustment box, and a ball nozzle is rotatably connected to the air supply pipe. The upper end of the contact frame is located on the side of the ball nozzle, and the ball nozzle forms a rotating structure with the air supply pipe through the contact action of the contact frame.

[0016] Compared with the prior art, the beneficial effects of the present invention are: (1) A heating box is provided. After the stained specimen is placed inside the placement box, the warm air blower is turned on. At this time, the warm air blower can deliver heat-carrying gas to the inside of the regulating box. Part of the gas will flow out through the preheating tank to preheat the inside of the placement box. The other part of the gas enters the gas supply pipe and is sprayed out through the ball nozzle to complete the heating treatment of the heating box and perform preliminary drying of the specimen placed on the placement box. This reduces the moisture on the surface of the specimen, so as to facilitate better observation of the specimen in the future and ensure the accuracy of the test results.

[0017] (2) Manually rotate the threaded rod so that the connecting plate gradually approaches the slide groove and the traction rope gradually loosens. At this time, the rotating shaft is not restricted by the traction force of the traction rope. The rotating shaft rotates under the elastic reset action of the torsion spring. The heating plate will gradually rotate from the vertical state to the horizontal state to heat the bottom of the placement box, further accelerating the drying speed of the specimen preparation, providing good sample conditions for subsequent pathological testing, and helping to improve the accuracy and efficiency of specimen preparation and testing during liver cancer biopsy.

[0018] (3) When the placement box is moved to the position below the heating box, the sealing plate will seal the preheating tank to prevent heat loss, so that the gas can only enter the gas supply pipe through the vent. The intermittently turned-on warm air machine will cause the air pressure in the regulating box to change. When the warm air machine is turned on, the air pressure in the regulating box increases, pushing the piston plate to slide to both sides. The ball nozzle rotates around the gas supply pipe, changing the direction of the gas ejection, so as to achieve large-scale heating treatment inside the heating box. When the warm air machine is turned off, the air pressure in the regulating box decreases. Under the action of the return spring, the ball nozzle also returns to the initial position. This cycle continues. Through the action of the swing mechanism, the heat distribution in the heating box is more uniform, improving the effect and efficiency of specimen preparation and drying.

[0019] (4) After being heated and dried, the specimens are transported to the bottom of the testing rack by the conveyor belt. The specimens are then subjected to pathological testing under the action of the testing rack, providing an accurate and reliable basis for the diagnosis of liver cancer. Multiple samples can be tested at the same time, which greatly improves the testing efficiency and avoids errors and contamination that may be caused by manual operation. Attached Figure Description

[0020] Figure 1 This is a three-dimensional structural diagram of the present invention; Figure 2 This is a three-dimensional structural diagram of the heating box of the present invention; Figure 3 This is a three-dimensional cross-sectional view of the heating box of the present invention; Figure 4 For the present invention Figure 4 Enlarged structural diagram at point A in the middle; Figure 5 This is a schematic diagram of the three-dimensional structure of the placement box of the present invention; Figure 6 This is a schematic diagram of the three-dimensional structure of the threaded rod of the present invention; Figure 7 This is a three-dimensional structural diagram of the adjustment box of the present invention; Figure 8 This is a schematic diagram of the three-dimensional structure of the piston plate of the present invention; Figure 9 This is a three-dimensional structural diagram of the spherical nozzle of the present invention in its oscillating state.

[0021] In the diagram: 1. Platform; 2. Testing frame; 3. Conveyor belt; 4. Heating box; 5. Placement box; 6. Warm air blower; 7. Threaded rod; 8. Connecting plate; 9. Slide groove; 10. Sealing plate; 11. Heating plate; 12. Traction rope; 13. Rotating shaft; 14. Torsion spring; 15. Adjustment box; 16. Piston plate; 17. Preheating tank; 18. Air supply pipe; 19. Ball nozzle; 20. Contact frame; 21. Vent hole; 22. Return spring; 23. Slide rod. Detailed Implementation

[0022] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0023] Example 1: To effectively reduce the moisture content on the surface of the specimen, creating favorable conditions for subsequent observation and preventing the details of the specimen from being blurred due to excessive moisture, thus affecting the clarity and accuracy of observation, such as... Figure 1 and Figure 2The present invention provides the following technical solution: a specimen preparation and testing device for liver cancer biopsy, comprising a testing rack 2 for testing specimens on the upper surface of a table 1, a conveyor belt 3 for adjusting the position of the specimens on the front side of the table 1, and a heating box 4 for drying stained specimens fixedly connected above the conveyor belt 3. The heating box 4 contains a placement box 5 for placing the prepared specimens, and a connecting plate 8 is fixedly connected to the side of the placement box 5. A sliding groove 9 is provided on the side of the heating box 4. A threaded rod 7 is rotatably connected to the upper part of the heating box 4. A threaded connection is made between the connecting plate 8 and the threaded rod 7. The connecting plate 8 forms a sliding structure with the sliding groove 9 through the threaded rod 7. An adjusting box 15 is fixedly connected inside the heating box 4. A preheating groove 17 for gas to flow out is opened at the lower inner side of the adjusting box 15. A gas supply pipe 18 is connected to the side of the adjusting box 15. A spherical nozzle 19 is rotatably connected to the gas supply pipe 18. The upper end of the contact frame 20 is located on the side of the spherical nozzle 19. The spherical nozzle 19 forms a rotating structure with the gas supply pipe 18 through the contact action of the contact frame 20.

[0024] After the stained specimens are properly placed inside the placement box 5, the operator starts the heater 6. The heater 6 then operates efficiently, delivering gas carrying a large amount of heat. After entering the heating box 4, the gas flows along two different paths. One part of the gas flows out through the preheating tank 17, where the hot gas evenly and gently preheats the environment inside the placement box 5, allowing the specimens to gradually adapt to temperature changes and avoiding potential damage due to sudden temperature fluctuations. The other part of the gas enters the gas supply pipe 18, which accurately guides the hot gas to the spherical nozzle 19 for even outward spraying. This ensures that all areas inside the heating box 4 receive balanced heat radiation, thus completing a comprehensive and efficient heating process. This preliminary drying ensures that the specimens can be observed more clearly and accurately under microscopes and other observation equipment, providing a solid and reliable guarantee for the accuracy of the test results.

[0025] Example 2: For specimen preparation in liver cancer biopsy, rapid drying is crucial. It maximizes the preservation of the specimen's original characteristics and structure, providing excellent sample conditions for subsequent pathological testing. To further improve drying efficiency, such as... Figures 3-6The present invention provides the following technical solution: a specimen preparation and testing device for liver cancer biopsy, wherein a connecting plate 8 is slidably connected inside a slide groove 9, and a fitting mechanism is provided between the connecting plate 8 and the slide groove 9. The fitting mechanism drives the heating plate 11 contained therein to rotate through the movement of the connecting plate 8, thereby achieving heating treatment of the bottom of the placement box 5. The fitting mechanism includes a rotating shaft 13, which is rotatably connected to the lower surface of the placement box 5, and both sides of the rotating shaft 13 are fixedly connected to the heating plate 11. When the placement box 5 is located above the heating box 4, the heating plate 11 is set in a vertical state. A traction rope 12 is wound around the outside of the rotating shaft 13, and the other side of the traction rope 12... One side is wrapped around the lower part of the connecting plate 8 and fixedly connected to the lower side of the slide 9. Two sets of traction ropes 12 are symmetrically arranged about the center point of the connecting plate 8. A torsion spring 14 is fixedly connected between the middle part of the rotating shaft 13 and the lower surface of the placement box 5. When the placement box 5 is located below the heating box 4, the heating plate 11 is set in a horizontal state and the heating plate 11 is in contact with the lower surface of the placement box 5. A heater 6 that is turned on intermittently is fixedly connected to the side of the heating box 4, and the output end of the heater 6 is connected to the regulating box 15. A sealing plate 10 is fixedly connected to the side of the placement box 5. When the placement box 5 is located below the heating box 4, the sealing plate 10 seals the preheating groove 17.

[0026] First, the operator manually and slowly rotates the threaded rod 7. The connecting plate 8, which is tightly fitted with it, begins to move under the drive of the thread. Since the connecting plate 8 is slidably set in the slide groove 9, it is guided and constrained by the slide groove 9. The connecting plate 8 slides smoothly along the path specified by the slide groove 9, thus driving the placement box 5 to move downward together. As the connecting plate 8 gradually slides down in the slide groove 9 and approaches the end of the slide groove 9, the originally taut traction rope 12 begins to loosen. The rotating shaft 13 is no longer restricted by the strong traction force of the traction rope 12. The torsion spring 14 installed on the rotating shaft 13, after losing its external constraint, begins to exert its elastic restoring characteristic, releasing the stored energy and driving the rotating shaft 13 to rotate. Since the rotating shaft 13 is fixedly connected to the heating plate 11, when the rotating shaft 13 rotates, the heating plate 11 also begins to move, gradually rotating from the original vertical state to the horizontal state. The heating plate 11 precisely fits against the lower surface of the placement box 5. Heat is released and rapidly transferred to the bottom of the placement box 5 through the tightly fitting surface, heating the specimen placed inside the placement box 5 and further accelerating the evaporation rate of surface moisture, significantly improving drying efficiency and effectively enhancing the accuracy and efficiency of specimen preparation and testing during liver cancer biopsy. When the operator needs to adjust the position of the placement box 5 to move it upward back to the initial position above the heating box 4, the connecting plate 8 slides upward along the slide groove 9 under the reverse drive of the threaded rod 7. The connecting plate 8 gradually drives the traction rope 12, causing it to gradually change from a loose state to a taut state. The tautness of the traction rope 12 generates a reverse pull, causing the rotating shaft 13 to rotate in the opposite direction under the pull. As the rotating shaft 13 rotates in the opposite direction, the heating plate 11, which is fixedly connected to it, also gradually returns from a horizontal state to a vertical state, returning to the initial standby position, which is convenient for subsequent operation and use according to actual needs. The design of the entire device reflects a high degree of scientificity and practicality.

[0027] Example 3: To ensure specimens reach the ideal drying state in a shorter time, providing high-quality samples for subsequent pathological testing, and helping doctors to more accurately assess and diagnose the condition, thus saving valuable time for patient treatment, such as... Figures 6-9The present invention provides the following technical solution: a specimen preparation and testing device for liver cancer biopsy, wherein an adjustment box 15 is provided with a swing mechanism, which realizes large-scale heating treatment of the interior of the heating box 4 by moving the contact frame 20 included therein. The swing mechanism includes a piston plate 16, which is slidably connected to the interior of the adjustment box 15, and the piston plate 16 has a vent hole 21 on its side. The piston plate 16 is located on the left and right sides of the preheating tank 17. A slide rod 23 is fixedly connected to the middle of the piston plate 16, and the slide rod 23 is slidably connected to the side of the adjustment box 15. The contact frame 20 is fixedly connected to the outer side of the slide rod 23. A return spring 22 is fixedly connected between the piston plate 16 and the inner wall of the adjustment box 15.

[0028] In the operation of the specimen processing device, when the placement box 5 moves to the position below the heating box 4 under the drive of the connecting plate 8, the sealing plate 10 tightly seals the preheating tank 17, effectively preventing the unnecessary loss of heat and ensuring that the heat can be concentrated and utilized. Under the action of the sealing plate 10, the gas is forced to enter the gas supply pipe 18 only through the carefully opened vent hole 21 on the piston plate 16, laying the foundation for the subsequent heating process. As the gas continuously flows into the regulating box 15, the gas pressure in the regulating box 15 gradually increases, forming a strong pressure. Under the action of this pressure, the piston plate 16 overcomes the elastic force of the return spring 22 and slowly slides to both sides, driving the connected slide rod 23 and the contact frame 20 to move together. The slide rod 23 moves along the piston plate 16. Under the influence of the movement, the contact frame 20 gradually approaches the spherical nozzle 19, eventually coming into contact with it. This causes the spherical nozzle 19 to deflect at an angle, rotating and changing the direction of the gas ejection. This allows the gas to be sprayed into the heating box 4 at different angles and ranges, achieving large-scale heating treatment inside the heating box 4. The intermittently turned-on warm air blower 6 regulates the air pressure changes inside the regulating box 15. When the warm air blower 6 is turned on, the air pressure inside the regulating box 15 increases rapidly. When the warm air blower 6 is turned off, the gas supply inside the regulating box 15 is interrupted, and the air pressure gradually decreases, causing the spherical nozzle 19 to rotate back and forth. This makes the heat distribution inside the heating box 4 more uniform, and the uniform heat distribution greatly improves the effect and efficiency of specimen preparation and drying.

[0029] Working principle: After the specimens have completed the staining process and are placed in the placement box 5, the warm air blower 6 is turned on. The gas enters the heating box 4 and flows in two directions: one part flows out through the preheating tank 17 to preheat the environment below the placement box 5 and prevent the specimens from being damaged by sudden temperature changes; the other part enters the gas supply pipe 18 and is evenly sprayed out through the spherical nozzle 19 to fully heat the heating box 4. The operator rotates the threaded rod 7, and the connecting plate 8 moves the placement box 5 down along the slide groove 9. The traction rope 12 is loosened, and the torsion spring 14 drives the rotating shaft 13 to rotate. The heating plate 11 rotates to a horizontal position and is in contact with the lower surface of the placement box 5 to accelerate the evaporation of moisture.

[0030] When the placement box 5 moves down below the heating box 4, the sealing plate 10 seals the preheating tank 17. Gas enters the gas supply pipe 18 through the vent 21. The increased gas pressure causes the piston plate 16 to slide, which drives the contact frame 20 to deflect the spherical nozzle 19, changing the direction of gas injection and achieving large-area heating. The intermittently turned warm air blower 6 regulates the gas pressure and drives the spherical nozzle 19 to rotate back and forth, making the heat distribution uniform and improving the drying effect and efficiency.

[0031] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A specimen preparation and testing device for liver cancer biopsy, comprising a table (1), a testing frame (2) disposed on the upper surface of the table (1), a conveyor belt (3) disposed on the front side of the table (1), and a heating box (4) fixedly connected above the conveyor belt (3), characterized in that, The heating box (4) is provided with a placement box (5) inside, and a connecting plate (8) is fixedly connected to the side of the placement box (5). A sliding groove (9) is provided on the side of the heating box (4). A fitting mechanism is provided between the connecting plate (8) and the sliding groove (9). The fitting mechanism drives the heating plate (11) contained therein to rotate by the movement of the connecting plate (8). An adjustment box (15) is fixedly connected inside the heating box (4). A swing mechanism is provided on the adjustment box (15). The swing mechanism realizes large-area heating treatment inside the heating box (4) by the movement of the contact frame (20) contained therein. The fitting mechanism includes a rotating shaft (13). The rotating shaft (13) is rotatably connected to the lower surface of the placement box (5), and the two sides of the rotating shaft (13) are fixedly connected to the heating plate (11). When the placement box (5) is located above the heating box (4), the heating plate (11) is set in a vertical state. An intermittently turned-on heater is fixedly connected to the side of the heating box (4). (6), and the output end of the heater (6) is connected to the regulating box (15). A preheating groove (17) for gas to flow out is opened at the lower inner side of the regulating box (15). A sealing plate (10) is fixedly connected to the side of the placement box (5). When the placement box (5) is located below the heating box (4), the sealing plate (10) seals the preheating groove (17). The swing mechanism includes a piston plate (16). The piston plate (16) is slidably connected to the heating box (4). The inside of the regulating box (15) has a vent hole (21) on the side of the piston plate (16), and the piston plate (16) is located on the left and right sides of the preheating tank (17). A slide rod (23) is fixedly connected to the middle of the piston plate (16). The slide rod (23) is slidably connected to the side of the regulating box (15), and an abutment frame (20) is fixedly connected to the outside of the slide rod (23). A return spring (22) is fixedly connected between the piston plate (16) and the inner wall of the regulating box (15).

2. The specimen preparation and testing device for liver cancer biopsy according to claim 1, characterized in that: The connecting plate (8) is slidably connected inside the slide groove (9), and a threaded rod (7) is rotatably connected to the slide groove (9). The connecting plate (8) and the threaded rod (7) are threadedly connected, and the connecting plate (8) and the slide groove (9) form a sliding structure through the threaded rod (7).

3. The specimen preparation and testing device for liver cancer biopsy according to claim 2, characterized in that: The outer side of the rotating shaft (13) is wound with a traction rope (12), and the other side of the traction rope (12) is wound around the bottom of the connecting plate (8) and fixedly connected to the lower side of the slide groove (9). The traction rope (12) is symmetrically arranged in two sets about the center point of the connecting plate (8).

4. The specimen preparation and testing device for liver cancer biopsy according to claim 3, characterized in that: A torsion spring (14) is fixedly connected between the middle part of the rotating shaft (13) and the lower surface of the placement box (5). When the placement box (5) is located below the heating box (4), the heating plate (11) is set in a horizontal state, and the heating plate (11) and the lower surface of the placement box (5) are in contact with each other.

5. The specimen preparation and testing device for liver cancer biopsy according to claim 4, characterized in that: An air supply pipe (18) is connected to the side of the adjustment box (15), and a ball nozzle (19) is rotatably connected to the air supply pipe (18). The upper end of the contact frame (20) is located on the side of the ball nozzle (19). The ball nozzle (19) forms a rotating structure with the air supply pipe (18) through the contact action of the contact frame (20).

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