青钱柳结合态硒多糖的分段酶解-梯级膜分离提取方法及其制得的结合态硒多糖
By employing segmented enzymatic hydrolysis and step-by-step membrane separation extraction methods, the problem of component mixing during the extraction of Cyclocarya paliurus polysaccharides in existing technologies has been solved, enabling the preparation of high-purity Cyclocarya paliurus bound selenium polysaccharides and improving the molecular weight distribution and human absorption efficiency of the product.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- HUBEI SIHUI BIOTECHNOLOGY CO LTD
- Filing Date
- 2026-04-03
- Publication Date
- 2026-07-17
AI Technical Summary
In the current extraction process of Eucommia ulmoides polysaccharides or selenium-containing polysaccharides, the low molecular weight components in the front stage and the target components in the back stage enter the final product together, resulting in a wide molecular weight distribution, a high proportion of inorganic selenium, and high protein and ash content, leading to low absorption and utilization rate by the human body.
A segmented enzymatic hydrolysis-step membrane separation and extraction method was adopted. In the first stage, the low molecular weight selenium-containing component stream was separated by nanofiltration after enzymatic hydrolysis. In the second stage, the target component liquid was separated by microfiltration and ultrafiltration after enzymatic hydrolysis, followed by nanofiltration washing and ethanol precipitation to limit the molecular weight and recovery path of the target component.
It improves the molecular weight distribution concentration of the target components, reduces the proportion of inorganic selenium, enhances the polysaccharide mass fraction and human absorption and utilization rate, and obtains purer Cyclocarya paliurus-bound selenium polysaccharides.
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Figure CN121949595B_ABST