A smoke odor removing spray and a method of preparing the same

Abstract

The present application relates to the technical field of deodorizing agent, and particularly discloses a smoke-odor-removing spray and a preparation method thereof, which comprises the following components in mass percentage: active odor-removing factor 3-4%, bamboo extract 1-2%, tea extract 0.5-0.8%, grapefruit peel extract 0.1-0.5%, fragrance 0.7-0.9%, humectant 0.5-0.7%, dispersant 0.4-0.6%, and stabilizer 0.2-0.3%, and the rest is water. The present application also provides a preparation method thereof. Compared with the prior art, the spray prepared by the present application has a good removal effect on various odor gases including nicotine, has a long deodorizing effect, and is safe and non-toxic due to the addition of various plant extract components.

Description

Technical Field

[0001] This invention relates to the field of deodorizing agents, and in particular to a smoke-removing spray and its preparation method. Background Technology

[0002] Secondhand smoke is often more harmful to health than firsthand smoke, and even for smokers themselves, the effects of secondhand smoke can be greater than those of direct smoking. The smoke produced when cigarettes burn contains over 4,000 chemicals, at least 60 of which are known carcinogens. Nicotine in tobacco is not only highly addictive but also significantly increases the risk of cardiovascular disease, easily leading to critical illnesses such as heart disease and stroke. Simultaneously, carbon monoxide in the smoke reduces the blood's oxygen-carrying capacity, causing symptoms such as dizziness and fatigue. Long-term exposure to secondhand smoke also significantly increases the likelihood of respiratory diseases such as emphysema and chronic bronchitis.

[0003] Furthermore, tobacco smoke is a complex aerosol containing thousands of chemical substances, with its odor molecules, such as nicotine, tar derivatives, and pyridine, exhibiting extremely strong adhesion and penetrability. These molecules can quickly adhere to walls, furniture, curtains, carpets, and even air conditioning systems, forming persistent "third-hand smoke" residue. This residual odor is not only an olfactory nuisance but also a continuous source of micro-pollution releasing harmful substances, potentially posing risks to the respiratory systems of long-term exposure individuals, especially children and sensitive populations. In addition, persistent smoke odor can severely degrade the quality of living and working environments. Therefore, eliminating smoke odor is an essential action related to health and well-being.

[0004] Patent CN110041999A discloses a composition for removing nicotine and smoke odor. This composition comprises 10-90% fragrance, 0.5-50% nicotine remover, and 1-90% solvent by weight. The patent also discloses a preparation method and applications of this composition. This composition can effectively remove harmful nicotine substances from automobiles, homes, public environments, etc., and can also quickly eliminate smoke odor and purify the air. Based on this composition, various products can be formulated, and the preparation method is simple and easy to operate. It is a fragrant, environmentally friendly smoke odor removal composition.

[0005] Patent CN116870680A discloses a method for preparing an odor-removing product. The method first involves dispersing hydroxypropyl methylcellulose and chitosan in water at a mass ratio of 1:1 and stirring to form a uniform and stable aqueous dispersion a. Peracetic acid and a copper ion catalyst are then added to this dispersion, and the mixture is heated at 80-100°C for 3-5 hours to obtain an aqueous dispersion b. Glucose is then added to dispersion b to remove excess peracetic acid, and heating continues for 1 hour. After cooling, a cross-linked aqueous solution of hydroxypropyl methylcellulose and chitosan is obtained. Urea is then added to the hydrogen peroxide solution, and the mixture is stirred at 40-50°C for 1 hour. Cyclodextrin is then added, and the mixture is stirred continuously at this temperature for another 1 hour. After cooling to room temperature, a stable hydrogen peroxide solution is obtained. Finally, the two aqueous solutions are mixed in a ratio of 1:5 to 1:1, sodium chlorite is added, and the mixture is stirred thoroughly to obtain the target odor-removing product.

[0006] Currently available sprays can be broadly categorized into two types: one uses a combination of plant extracts and surfactants to naturally decompose odors; the other contains synthetic compounds such as chlorine dioxide to oxidize odor molecules. However, masking or decomposing smoke odors through the fragrance of extracts is only partially effective. Furthermore, strong oxidants like chlorine dioxide are irritating to the respiratory tract and eyes, and improper concentrations in enclosed spaces like homes can pose health risks. Additionally, they have strong oxidizing, bleaching, and corrosive effects on metals, electronic devices, colored fabrics, leather, and artwork, potentially causing fading or damage. Summary of the Invention

[0007] In view of the above-mentioned deficiencies of the prior art, the technical problem to be solved by the present invention is to provide a smoke deodorizing spray and a method for preparing the same.

[0008] The unique cavity structure of β-cyclodextrin allows it to encapsulate various odor molecules, such as those from smoke, within its hydrophobic cavities, forming stable inclusion complexes. Once encapsulated, these odor molecules lose their volatility, thus achieving a deodorizing effect. However, cyclodextrin primarily relies on physical encapsulation, and this encapsulation effect may be disrupted under high temperature, high humidity, or prolonged physical friction, causing some odor molecules to be released again.

[0009] Therefore, this invention provides an active deodorizing factor that uses hydroxypropyl-β-cyclodextrin, which has better water solubility, to chemically combine with hydrolyzed gluconolactone. The multiple hydroxyl groups contained therein can form additional hydrogen bonds with the encapsulated tobacco odor molecules, achieving chemical bonding in addition to physical encapsulation. The addition of purines can further complex with cyclodextrin, and the purine rings can undergo π-π stacking with the aromatic rings of tobacco and other odor molecules, further enhancing the binding effect. The amino and carbonyl groups of purine substances can also provide additional hydrogen bond sites, making the structure of the odor molecules bound to them more stable and prolonging the deodorizing effect.

[0010] In this invention, bamboo extract contains flavonoids, which possess certain adsorption properties, assisting in the adsorption of trace odor molecules while releasing a natural herbal aroma. Tea extract has a strong antibacterial and deodorizing effect, inhibiting secondary odors caused by bacterial growth in smoky environments and further improving air quality. Grapefruit peel extract, as a natural fragrance and odor masking agent, significantly improves the atmosphere of odorous environments. The refreshing aroma of sweet orange essential oil also gently masks the faint odor of residual smoke. Glycerin, as a humectant, enhances the wettability of the spray, preventing component aggregation caused by rapid droplet drying. Polyethylene glycol adjusts the atomization effect of the spray, reducing liquid surface tension and ensuring uniform distribution of components within the droplets. Hydroxyethyl cellulose, as a stabilizer, prevents component stratification and sedimentation through a slight thickening effect, ensuring the spray maintains a uniform dispersion even after long-term storage, thus maintaining consistent deodorizing effects.

[0011] To achieve the above objectives, the present invention provides a smoke deodorizing spray comprising the following components by weight percentage: 3-4% active deodorizing factor, 1-2% bamboo extract, 0.5-0.8% tea extract, 0.1-0.5% grapefruit peel extract, 0.7-0.9% fragrance, 0.5-0.7% humectant, 0.4-0.6% dispersant, and 0.2-0.3% stabilizer, with the balance being water.

[0012] The preparation method of the active odor-removing factor includes the following steps: Add gluconolactone to a mixture of tert-butanol and water, adjust the pH to weakly acidic, and stir at 35-40℃ for 1-2 hours. Then add EDC·HCl and NHS, stir for 20-30 minutes, add hydroxypropyl-β-cyclodextrin, heat and stir for 30-40 hours, adjust the pH to near neutral, stir for 20-30 minutes, add purine monomer, disperse evenly by ultrasonication, stir at 40-50℃ for 20-30 hours, add an equal volume of ethanol, let stand, filter, wash, and dry to obtain the active deodorizing factor.

[0013] Furthermore, the volume ratio of the mixture of tert-butanol and water is 3-4:1.

[0014] Furthermore, the mass ratio of the mixture of tert-butanol and water, hydroxypropyl-β-cyclodextrin, gluconolactone, EDC·HCl, NHS and purine monomer is 40-50:8-10:1-2:0.4-0.6:0.2-0.3:2-5.

[0015] Furthermore, the temperature range for the heating is 40-50℃.

[0016] Furthermore, the purine monomer is one of adenine, xanthine, or purine base.

[0017] Furthermore, the fragrance is sweet orange essential oil.

[0018] Furthermore, the moisturizer is glycerin.

[0019] Furthermore, the dispersant is polyethylene glycol.

[0020] Furthermore, the stabilizer is hydroxyethyl cellulose.

[0021] Preferably, the preparation method of the active deodorizing factor includes the following steps: Add gluconolactone to a mixture of tert-butanol and water, adjust the pH to weakly acidic, and stir at 35-40℃ for 1-2 hours. Then add EDC·HCl and NHS, stir for 20-30 minutes, add hydroxypropyl-β-cyclodextrin, heat to 40-50℃ and stir for 30-40 hours. Adjust the pH to near neutral, stir for 20-30 minutes, and then add purine monomer. The mass ratio of the mixture of tert-butanol and water, hydroxypropyl-β-cyclodextrin, gluconolactone, EDC·HCl, NHS and purine monomer is 40-50:8-10:1-2:0.4-0.6:0.2-0.3:2-5. Disperse evenly by ultrasonication, stir at 40-50℃ for 20-30 hours, add an equal volume of ethanol, let stand, filter, wash and dry to obtain the active deodorizing factor.

[0022] A method for preparing a smoke deodorizing spray includes the following steps: After adding a stabilizer to the water and stirring well, add a humectant, dispersant, active odor-removing agent, bamboo extract, tea extract, and grapefruit peel extract, mix well, add a fragrance, add water, homogenize, filter, bottle, and seal to obtain the smoke-removing spray.

[0023] The beneficial effects of this invention are: 1. Compared with the prior art, the present invention provides an active deodorizing factor that uses hydroxypropyl-β-cyclodextrin, which has better water solubility, to chemically combine with hydrolyzed gluconolactone. The multiple hydroxyl groups contained therein can form additional hydrogen bonds with the encapsulated smoke molecules, achieving chemical bonding in addition to physical encapsulation. The addition of purines can further complex with cyclodextrin. The purine rings and the aromatic rings of various odor molecules such as smoke undergo π-π stacking, further enhancing the binding effect. The amino and carbonyl groups of purine substances can also provide additional hydrogen bond sites, making the structure of the odor molecules bound to them more stable and prolonging the deodorizing effect.

[0024] 2. In this invention, bamboo extract contains flavonoids, which have certain adsorption properties, while tea extract has strong antibacterial and deodorizing effects, inhibiting secondary odors caused by bacterial growth in smoky environments. Grapefruit peel extract can significantly improve the odorous atmosphere. Sweet orange essential oil gently masks the faint odor of residual smoke. Glycerin acts as a humectant, enhancing the wettability of the spray; polyethylene glycol adjusts the atomization effect of the spray and reduces the surface tension of the liquid; hydroxyethyl cellulose acts as a stabilizer, preventing the components from separating and settling through a slight thickening effect, maintaining the consistency of the deodorizing effect. Detailed Implementation

[0025] Bamboo extract, with an extraction ratio of 10:1, is sourced from Shaanxi Fubang Biotechnology Co., Ltd.

[0026] Tea extract, with an extraction ratio of 5:1, is sourced from Nanjing Daosifu Biotechnology Co., Ltd.

[0027] Grapefruit peel extract, with an extraction ratio of 10:1, is sourced from Baoji Kaiweikang Biotechnology Co., Ltd.

[0028] EDC·HCl, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, CAS No.: 25952-53-8.

[0029] NHS, N-hydroxysuccinimide, CAS No.: 6066-82-6.

[0030] Example 1

[0031] A method for preparing a smoke deodorizing spray includes the following steps, in parts by weight: Add 0.3 parts hydroxyethyl cellulose to 88 parts water and stir well. Then add 0.7 parts glycerin, 0.6 parts PEG-400, 3.5 parts active odor-removing factor, 1.6 parts bamboo extract, 0.7 parts tea extract, and 0.3 parts grapefruit peel extract. Mix well, add 0.8 parts sweet orange essential oil, and add water to make up to 100 parts. Homogenize, filter, bottle, and seal to obtain the smoke-removing spray.

[0032] The preparation method of the active odor-removing factor includes the following steps: In a mixture of tert-butanol and water (V 叔丁醇 V 水Add gluconolactone to a mixture of 19:6, adjust the pH to 5.5 with 0.1 mol / L dilute hydrochloric acid, and stir at 40℃ for 2 h. Then add EDC·HCl and NHS, stir for 30 min, add hydroxypropyl-β-cyclodextrin, heat to 45℃ and stir for 36 h. Adjust the pH to 7.0 with 5 wt% sodium bicarbonate aqueous solution, stir for 30 min, and then add adenine. The mass ratio of a mixture of tert-butanol and water, hydroxypropyl-β-cyclodextrin, gluconolactone, EDC·HCl, NHS and adenine is 47.5:8.5:1.2:0.45:0.25:4. Disperse evenly by ultrasonication, stir at 50℃ for 24 h, add an equal volume of ethanol dropwise, let stand, filter, wash and dry to obtain the active deodorizing factor.

[0033] Example 2

[0034] A method for preparing a smoke deodorizing spray includes the following steps, in parts by weight: Add 0.3 parts hydroxyethyl cellulose to 88 parts water and stir well. Then add 0.7 parts glycerin, 0.6 parts PEG-400, 3.5 parts active odor-removing factor, 1.6 parts bamboo extract, 0.7 parts tea extract, and 0.3 parts grapefruit peel extract. Mix well, add 0.8 parts sweet orange essential oil, and add water to make up to 100 parts. Homogenize, filter, bottle, and seal to obtain the smoke-removing spray.

[0035] The preparation method of the active odor-removing factor includes the following steps: In a mixture of tert-butanol and water (V 叔丁醇 V 水 Add gluconolactone to a mixture of 19:6, adjust the pH to 5.5 with 0.1 mol / L dilute hydrochloric acid, and stir at 40℃ for 2 h. Then add EDC·HCl and NHS, stir for 30 min, add hydroxypropyl-β-cyclodextrin, heat to 45℃ and stir for 36 h. Adjust the pH to 7.0 with 5 wt% sodium bicarbonate aqueous solution, stir for 30 min, and then add xanthine, a mixture of tert-butanol and water, hydroxypropyl-β-cyclodextrin, gluconolactone, EDC·HCl, NHS and xanthine in a mass ratio of 47.5:8.5:1.2:0.45:0.25:4. Disperse evenly by ultrasonication, stir at 50℃ for 24 h, add an equal volume of ethanol dropwise, let stand, filter, wash and dry to obtain the active deodorizing factor.

[0036] Example 3

[0037] A method for preparing a smoke deodorizing spray includes the following steps, in parts by weight: Add 0.3 parts hydroxyethyl cellulose to 88 parts water and stir well. Then add 0.7 parts glycerin, 0.6 parts PEG-400, 3.5 parts active odor-removing factor, 1.6 parts bamboo extract, 0.7 parts tea extract, and 0.3 parts grapefruit peel extract. Mix well, add 0.8 parts sweet orange essential oil, and add water to make up to 100 parts. Homogenize, filter, bottle, and seal to obtain the smoke-removing spray.

[0038] The preparation method of the active odor-removing factor includes the following steps: In a mixture of tert-butanol and water (V 叔丁醇 V 水 Add gluconolactone to a mixture of 19:6, adjust the pH to 5.5 with 0.1 mol / L dilute hydrochloric acid, and stir at 40℃ for 2 h. Then add EDC·HCl and NHS, stir for 30 min, add hydroxypropyl-β-cyclodextrin, heat to 45℃ and stir for 36 h. Adjust the pH to 7.0 with 5 wt% sodium bicarbonate aqueous solution, stir for 30 min, and then add purine base. The mass ratio of the mixture of tert-butanol and water, hydroxypropyl-β-cyclodextrin, gluconolactone, EDC·HCl, NHS and purine base is 47.5:8.5:1.2:0.45:0.25:4. Disperse evenly by ultrasonication, stir at 50℃ for 24 h, add an equal volume of ethanol dropwise, let stand, filter, wash and dry to obtain the active deodorizing factor.

[0039] Compare with Example 1

[0040] A method for preparing a smoke deodorizing spray includes the following steps, in parts by weight: Add 0.3 parts hydroxyethyl cellulose to 88 parts water and stir well. Then add 0.7 parts glycerin, 0.6 parts PEG-400, 3.5 parts hydroxypropyl-β-cyclodextrin, 1.6 parts bamboo extract, 0.7 parts tea extract, and 0.3 parts grapefruit peel extract. Mix well, add 0.8 parts sweet orange essential oil, and add water to make up to 100 parts. Homogenize, filter, bottle, and seal to obtain the smoke deodorizing spray.

[0041] Compare with Example 2

[0042] A method for preparing a smoke deodorizing spray includes the following steps, in parts by weight: Add 0.3 parts hydroxyethyl cellulose to 88 parts water and stir well. Then add 0.7 parts glycerin, 0.6 parts PEG-400, 3.5 parts active odor-removing factor, 1.6 parts bamboo extract, 0.7 parts tea extract, and 0.3 parts grapefruit peel extract. Mix well, add 0.8 parts sweet orange essential oil, and add water to make up to 100 parts. Homogenize, filter, bottle, and seal to obtain the smoke-removing spray.

[0043] The preparation method of the active odor-removing factor includes the following steps: In a mixture of tert-butanol and water (V 叔丁醇 V 水 Add gluconolactone to a mixture of 19:6, adjust the pH to 5.5 with 0.1 mol / L dilute hydrochloric acid, and stir at 40℃ for 2 h. Then add EDC·HCl and NHS, stir for 30 min, and add a mixture of hydroxypropyl-β-cyclodextrin, tert-butanol and water. The mass ratio of hydroxypropyl-β-cyclodextrin, gluconolactone, EDC·HCl and NHS is 47.5:8.5:1.2:0.45:0.25. Heat to 45℃ and stir for 36 h. After concentration and drying, the active deodorizing factor is obtained.

[0044] Test Example 1

[0045] Odor removal tests were conducted on the sprays prepared in the examples and control examples. The test method followed QB / T 2761-2006 "Test Method for Purification Effect of Indoor Air Purification Products". In a 15 cubic meter closed air test chamber, the removal rate of the purification product for the target pollutant was calculated by monitoring changes in pollutant concentration. The calculation formula was: Removal rate = (1-C) / (2π√(1-C) ...) / (2π√(1-C)) / (2π√(1-C) 终 / C 初 )×100%(C 初 For the initial concentration, C 终 (Concentration at the end of the experiment).

[0046] Table 1

[0047] As shown in Table 1, the spray prepared in this invention has a good removal effect on various toxic and odorous gases such as nicotine, ammonia, and formaldehyde. This may be because bamboo extract contains flavonoids, which have certain adsorption properties and can help adsorb trace amounts of various odor molecules while releasing natural herbal aromas. Tea extract has a strong antibacterial and deodorizing effect, which can inhibit the secondary odors caused by bacterial growth in smoky environments, further improving air quality. Grapefruit peel extract, as a natural fragrance and odor masking agent, can significantly improve the atmosphere of odorous environments. The unique cavity structure of β-cyclodextrin allows it to encapsulate various odor molecules inside the hydrophobic cavity of cyclodextrin, forming stable inclusion complexes. Once encapsulated, the odor molecules lose their volatility, thereby achieving the removal effect.

[0048] Compared to the physical encapsulation in Comparative Example 1, Comparative Example 2 utilizes the more water-soluble hydroxypropyl-β-cyclodextrin to chemically bind with hydrolyzed gluconolactone. The multiple hydroxyl groups in hydroxypropyl-β-cyclodextrin can form additional hydrogen bonds with the encapsulated odor molecules, achieving chemical binding beyond physical encapsulation. Furthermore, the addition of purines in this example allows for further complexation with the cyclodextrin. The purine rings and the aromatic rings of the odor molecules undergo π-π stacking, further enhancing the binding effect. The amino and carbonyl groups of purine substances also provide additional hydrogen bond sites, making the structure of the odor molecules bound to them more stable. Therefore, the removal effect is better than that of the Comparative Example.

[0049] Example 2 showed the best removal effect, which may be because xanthine has multiple amino and carbonyl groups, resulting in more hydrogen bond binding sites and the highest binding efficiency with odor molecules, thus removing them more thoroughly.

[0050] Test Example 2

[0051] After the odor removal standards were met, the pollutant concentrations were placed naturally in each sealed chamber and monitored periodically. The concentrations were recorded so that the concentrations in the sealed chambers corresponding to the samples from the implementation and control examples returned to the threshold (nicotine ≤ 0.05 mg / m³). 3 The above time was used to test the continuous deodorizing time of the spray.

[0052] Skin irritation tests were conducted on the sprays prepared in the examples and control examples according to GB / T 38496-2020 "Procedures and Methods for Toxicological Evaluation of Disinfectant Safety". Three healthy adult rabbits were used in each group. The hair on both sides of the spine on the back was shaved 24 hours before the test, with each side covering an area of ​​about 3cm × 3cm to ensure that the skin was intact and undamaged. The undiluted solution was used as the test substance. 0.5mL was evenly applied to one side of the shaved skin and covered and bandaged. The other side of the skin served as a blank control. After 4 hours of treatment, the test substance was washed off with warm water. Skin erythema and edema reactions were observed at 1, 24, 48 and 72 hours after removal and scored according to the standard. The average irritation index (DI) of each group was calculated, where DI < 0.5 was considered non-irritating.

[0053] Table 2

[0054] Irritation tests showed that the spray prepared in this invention is safe and mild, while continuous deodorization tests demonstrated that the spray has good residual effect. In the examples, hydroxypropyl-β-cyclodextrin, which has better water solubility, is chemically combined with hydrolyzed gluconolactone and purine rings. Through various chemical bonding interactions such as hydrogen bonding and π-π stacking, the structure of the odor molecules bound to it is more stable, effectively prolonging the deodorization time.

[0055] The preferred embodiments of the present invention have been described in detail above. It should be understood that those skilled in the art can make numerous modifications and variations based on the concept of the present invention without creative effort. Therefore, all technical solutions that can be obtained by those skilled in the art based on the concept of the present invention through logical analysis, reasoning, or limited experimentation on the basis of existing technology should be within the scope of protection defined by the claims.

Claims

1. A smoke deodorizing spray, characterized in that, It comprises the following components by weight percentage: bamboo extract 1-2%, tea extract 0.5-0.8%, grapefruit peel extract 0.1-0.5%, active deodorizing factor 3-4%, fragrance 0.7-0.9%, humectant 0.5-0.7%, dispersant 0.4-0.6%, and stabilizer 0.2-0.3%, with the balance being water; The preparation method of the active odor-removing factor includes the following steps: Add gluconolactone to a mixture of tert-butanol and water, adjust the pH to weakly acidic, and stir at 35-40℃ for 1-2 hours. Then add EDC·HCl and NHS, stir for 20-30 minutes, add hydroxypropyl-β-cyclodextrin, heat and stir for 30-40 hours, adjust the pH to near neutral, stir for 20-30 minutes, add purine monomer, disperse evenly by ultrasonication, stir at 40-50℃ for 20-30 hours, add an equal volume of ethanol, let stand, filter, wash, and dry to obtain the active deodorizing factor. The bamboo extract contains flavonoids.

2. The smoke-removing spray as described in claim 1, characterized in that, The volume ratio of the mixture of tert-butanol and water is 3-4:

1.

3. The smoke-removing spray as described in claim 1, characterized in that, The mass ratio of the mixture of tert-butanol and water, hydroxypropyl-β-cyclodextrin, gluconolactone, EDC·HCl, NHS and purine monomers is 40-50:8-10:1-2:0.4-0.6:0.2-0.3:2-5.

4. The smoke-removing spray as described in claim 1, characterized in that, The temperature range for the heating is 40-50℃.

5. The smoke-removing spray as described in claim 1, characterized in that, The purine monomer is one of adenine, xanthine, or purine base.

6. The smoke-removing spray as described in claim 1, characterized in that, The fragrance is sweet orange essential oil.

7. The smoke-removing spray as described in claim 1, characterized in that, The moisturizer is glycerin.

8. The smoke-removing spray as described in claim 1, characterized in that, The dispersant is polyethylene glycol.

9. The smoke-removing spray as described in claim 1, characterized in that, The stabilizer is hydroxyethyl cellulose.

10. The method for preparing the smoke-removing spray according to any one of claims 1-9, characterized in that, Includes the following steps: After adding a stabilizer to the water and stirring well, add a humectant, dispersant, active odor-removing agent, bamboo extract, tea extract, and grapefruit peel extract, mix well, add a fragrance, add water, homogenize, filter, bottle, and seal to obtain the smoke-removing spray.

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