一种促渗透皮纳米复合球肽及其制备方法和在制备头皮控油、防脱和抗衰产品中的应用
The preparation of nanocomposite spheroids using tocosolvan and poloxamer carriers solved the problems of solubility and stability of lipid-soluble peptides in water-based formulations, achieving efficient transdermal delivery and comprehensive cosmetic efficacy.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- ZHEJIANG HAOMAI TECH CO LTD
- Filing Date
- 2026-04-14
- Publication Date
- 2026-07-17
AI Technical Summary
In existing technologies, fat-soluble peptides exhibit poor solubility and low stability in water-based formulations, and their transdermal delivery is inadequate, making effective delivery difficult and hindering their commercial development and end-use efficacy in cosmetics.
Using tocoxelane and poloxamer as carriers, nanocomposite spheroids were prepared through a specific method to form a stable hydrophobic core and a hydrophilic protective layer, encapsulating lipid-soluble peptides and improving their permeability and stability in the skin.
It achieves highly efficient transdermal absorption of fat-soluble peptides, enhances the oil-controlling, hair loss-preventing, and anti-aging effects of cosmetics, promotes collagen production, and improves scalp health.
Smart Images

Figure CN122005348B_ABST