基于条纹相机的宽场荧光寿命成像系统及其成像方法
By introducing a fluorescence lifetime imaging system that combines a reference camera and a streak camera working in parallel, the problems of high photon loss and low imaging efficiency in existing technologies have been solved. This enables high-precision fluorescence lifetime reconstruction and real-time monitoring, improving the system's stability and imaging efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SHENZHEN UNIV
- Filing Date
- 2026-04-24
- Publication Date
- 2026-07-17
AI Technical Summary
Existing fluorescence lifetime imaging systems based on streak cameras suffer from high photon loss and low imaging efficiency, especially when using DMD encoders, where photon efficiency is reduced and system stability and robustness are limited.
The reference camera and the stripe camera work in parallel. The fluorescence beam is split into two paths by a collection and beam splitting component. The reference camera acquires a two-dimensional spatial intensity image as a physical spatial reference, and the stripe camera acquires fluorescence decay time information. Combined with a synchronization matching module, the excitation source and the stripe camera are synchronized and controlled, avoiding complex spatial coding and reconstruction algorithms and simplifying the system structure.
It achieves high-precision fluorescence lifetime reconstruction, reduces hardware costs and data processing pressure, improves imaging efficiency and system stability, supports real-time monitoring at higher frame rates, and enhances the detection accuracy and real-time imaging performance of weak fluorescence samples.
Smart Images
Figure CN122084592B_ABST