A meropenem precision infusion regulating device suitable for different pathogenic bacteria

Abstract

The application relates to the technical field of medical devices and discloses a meropenem precision infusion regulating device suitable for different pathogenic bacteria, which comprises a rear shell, a front shell arranged at the front end of the rear shell, a push slide rod slidingly inserted into the front shell, a push box fixed to one end of the push slide rod extending out of the front shell, a stroke piece fixed to the front shell, a liquid driving piece slidingly arranged on the stroke piece, a power piece fixed to the inner bottom of the rear shell and the front shell, a clamping piece slidingly inserted into the front shell, and two mounting grooves arranged on the front shell. The application is designed as a core through a liquid capsule modular driving design, completely gets rid of a traditional mechanical transmission mode, avoids mechanical wear problems existing in the traditional mechanical transmission from the root, effectively solves the problem of precision reduction after long-term use, realizes adjustable infusion of meropenem, keeps the blood drug concentration of the medicine in the body to be optimal, and provides precise, efficient and safe anti-infection treatment for different pathogenic bacterial infections.

Description

[0001] This invention relates to the field of medical device technology, specifically to a meropenem precision infusion control device adapted to different pathogens. Background Technology

[0002] Meropenem, a broad-spectrum carbapenem antibiotic, plays a crucial role in the clinical treatment of various pathogenic infections. Its therapeutic effect is highly correlated with the stability of its blood drug concentration. Different pathogens exhibit significant differences in their sensitivity to meropenem. Infections with sensitive bacteria require maintaining moderate blood drug concentrations, while infections with drug-resistant bacteria require higher concentrations. Over-infusion can easily lead to adverse reactions such as epilepsy and renal damage, while under-infusion may result in poor infection control or even drug resistance. Therefore, the precision of meropenem infusion is extremely important in clinical practice, requiring not only strict control of the infusion dose but also flexible adjustment of the infusion rate according to the type of pathogen.

[0003] Currently, micro-infusion pumps are widely used in clinical practice as the primary device for meropenem infusion. However, their core transmission structure employs traditional mechanical transmission methods, generally relying on the meshing or sliding cooperation of mechanical components such as lead screws, gears, and pistons to achieve power transmission and stroke control. This transmission method has inherent and unavoidable drawbacks. Mechanical components inevitably experience wear during long-term, repeated friction and meshing, and this wear intensifies with increased usage frequency and duration. Initially, this may manifest as increased transmission clearance, leading to minor deviations in the infusion stroke. Later, it may result in component jamming and disrupted transmission, directly causing a significant decrease in infusion accuracy and an inability to stably maintain the preset infusion dose and rate.

[0004] For antibiotics like meropenem, which are sensitive to blood drug concentration, even slight deviations in infusion accuracy can affect treatment efficacy. The decline in precision of traditional micro-infusion pumps after long-term use poses a significant risk to clinical treatment. Current technologies sometimes mitigate this problem by periodically replacing worn parts or increasing calibration frequency. However, this approach not only increases medical costs and maintenance workload but also fails to address the root cause of precision degradation due to mechanical wear. Furthermore, traditional mechanically driven micro-infusion pumps often require replacement of corresponding mechanical adapter parts when adapting to different syringe sizes, resulting in cumbersome operation, poor compatibility, and difficulty in meeting the personalized needs of patients with different pathogens regarding drug volume and infusion rate. Summary of the Invention

[0005] This invention provides a meropenem precision infusion control device adapted to different pathogens, which enables adjustable meropenem infusion, maintains the optimal blood drug concentration in the body, and provides precise, efficient and safe anti-infective treatment for infections caused by different pathogens.

[0006] To solve the above-mentioned technical problems, the technical solution of the present invention is as follows: In a first aspect, a meropenem precision infusion control device adapted to different pathogens includes: a rear shell and a front shell disposed at the front end of the rear shell, and further includes: A push rod is slidably inserted into the front housing; a push box is fixed to one end of the push rod extending out of the front housing; a stroke component is fixed inside the front housing; a hydraulic drive component is slidably mounted on the stroke component; a power component is fixed to the inner bottom of the rear housing and the front housing; a clamping component is slidably inserted into the front housing; two mounting slots are provided, and the two mounting slots are formed on the front housing; a locking slot is formed on the mounting slot. There are two stroke plates, both of which are fixed to the front shell; end sealing plates are fixed to both ends of the stroke plates; four stroke guide rods are provided, each of which is fixed to the end sealing plate; two guide rods are provided, both of which are fixed to both sides of the end sealing plate; side slide plates are fixed to both sides of the stroke plates; side slide seats are slidably mounted on the side slide plates; and a drive plate is fixed to the side slide seats from below. Multiple liquid-driven plates are provided, and each liquid-driven plate is slidably mounted on a travel guide rod; a bladder groove is formed inside the liquid-driven plate; a liquid bladder is fixed inside the bladder groove; a first movable hole is formed on the liquid-driven plate; an extension cylinder is slidably mounted inside the first movable hole; a second movable hole is formed inside the extension cylinder; an extension rod is slidably mounted inside the first movable hole; side plate grooves are formed on both sides of the liquid-driven plate; two liquid-driven side plates are provided, and both liquid-driven side plates are fixed on the extension rod and located inside the side plate groove; a liquid guide tube is fixed on the liquid-driven plate, and one end of the tube extends into the liquid bladder.

[0007] Furthermore, the travel component also includes: A travel groove is formed on the travel plate; a travel slider is slidably set in the travel groove and fixed above on one end of the push rod extending into the front housing; a spring ring is fixed on one end of the push rod extending into the front housing; a travel spring is fixed at one end in the front housing and at the other end on the spring ring and sleeved on the push rod.

[0008] Furthermore, the travel component also includes: The permanent magnet column is fixed on both sides of the stroke slider; the sensing hole is opened inside the stroke plate; the sensing shell is fixed inside the sensing hole; and the sensing coil is fixed inside the sensing shell.

[0009] Furthermore, the liquid drive component also includes: The stroke guide holes are opened on the four sides of the liquid drive plate and are slidably sleeved on the stroke guide rods; the guide holes are opened on both sides of the liquid drive plate and are slidably sleeved on the guide rods; the mounting holes are opened on the liquid drive plate; the first pair of pipes are fixedly inserted into the mounting holes at one end and sleeved on the liquid guide pipe at the other end.

[0010] Furthermore, the power component includes: A liquid storage box is fixed inside the rear and front shells; a first micro diaphragm pump is fixed inside the rear shell; a second micro diaphragm pump is fixed inside the rear shell; a support is fixed inside the front shell; a dispensing box is fixed on the support; a first suction pipe is fixed at one end to the liquid storage box and at the other end to the first micro diaphragm pump; a first supply pipe is fixed at one end to the first micro diaphragm pump and at the other end to the dispensing box; a first micro diaphragm solenoid valve is fixed on the first supply pipe; a second suction pipe is fixed at one end to the dispensing box and at the other end to the second micro diaphragm pump; a second supply pipe is fixed at one end to the second micro diaphragm pump and at the other end to the liquid storage box; a second micro diaphragm solenoid valve is fixed on the second supply pipe.

[0011] Furthermore, the power component also includes: The second pair of connectors is fixed to the separatory box; the third miniature diaphragm solenoid valve is fixed to the end of the second pair of connectors near the separatory box; and the Coriolis microflow meter is fixed to the end of the second pair of connectors away from the separatory box.

[0012] Furthermore, the clamping member includes: The first limiting cylinder is fixed inside the front housing; the limiting groove is formed on the first limiting cylinder; the limiting head is slidably disposed in the limiting groove; the second limiting cylinder is fixed on the outside of the front housing; the pull rod has one end fixed to the limiting head and the other end extending out of the second limiting cylinder; the clamping spring has one end fixed to the limiting head and the other end fixed inside the front housing and located inside the first limiting cylinder; the clamping head is fixed on one end of the pull rod extending out of the second limiting cylinder and is slidably connected to the second limiting cylinder.

[0013] Furthermore, the clamping member also includes: Two rotating rods are provided within the same push box, with one end of each rod rotatably mounted inside the push box and the other end extending out of the push box; two grippers are provided on the same push box, with each gripper fixed to the end of the rotating rod extending out of the push box; two transmission gears are provided within the same push box, with each transmission gear fixed to the rotating rod and located inside the push box, and the two transmission gears meshing with each other; two torsion springs are provided within the same push box, with one end of each torsion spring fixed inside the push box and the other end fixed to the transmission gear.

[0014] Furthermore, the clamping member also includes: The locking plate is fixed to the rear shell; the tightening rod is threaded onto the locking plate; the stop block is fixed to the end of the tightening rod located inside the locking plate; and the torsion wheel is fixed to the end of the tightening rod away from the stop block.

[0015] Furthermore, it also includes: The display screen is fixed on the top of the front shell; the button group is fixed on the top of the front shell; the adjustment knob is rotated on the front shell; the control panel is fixed inside the top of the front shell; and the foot plate is fixed on the bottom of the rear shell and the front shell.

[0016] The above-described solution of the present invention has at least the following beneficial effects: This invention, centered on a modular drive design for the liquid bladder, completely eliminates the traditional mechanical transmission mode, fundamentally avoiding the mechanical wear problems inherent in traditional mechanical transmissions and effectively solving the problem of decreased precision after long-term use. By controlling the volume of glycerin drawn from the bladder, its contraction degree can be precisely regulated, thereby driving the push rod and push box to push the syringe feed rate. In conjunction with a Coriolis micro-flowmeter, the amount of glycerin drawn is detected in real time and the data is synchronously transmitted to the control board. The control board performs precise comparison based on preset syringe model thresholds, promptly closing the current third micro-diaphragm solenoid valve and opening the next one, achieving modular control of the quantitative drug output corresponding to a single liquid bladder, flexibly adapting to different syringe models. A second micro-diaphragm pump is used to draw the liquid from each bladder. The timing of the glycerol injection precisely adjusts the syringe's drug delivery rate to meet the dosing rate requirements of different pathogen infections. Under the rebound force of the stroke spring, the liquid-driven side plates on both sides of the liquid-driven plate move closer to the side plate groove, the extension rod retracts into the second movable hole, and the extension cylinder retracts into the first movable hole, driving multiple liquid-driven plates to slide smoothly on the stroke guide rod and guide rod. This flexible drive method eliminates the vibration and wear of traditional mechanical transmission. Combined with the real-time detection of the stroke slider displacement by the induction coil, it further ensures the long-term stability of infusion accuracy. Furthermore, through the innovative combination of modular quantitative control and rate adjustment of the liquid capsule, meropenem infusion can be controlled, maintaining the optimal blood drug concentration in the body and providing precise, efficient, and safe anti-infective treatment for different pathogen infections. Attached Figure Description

[0017] Figure 1 A first-view overall structural diagram of a meropenem precision infusion control device adapted to different pathogens provided in an embodiment of the present invention; Figure 2 This is a second-view overall structural diagram of a meropenem precision infusion control device adapted to different pathogens, provided in an embodiment of the present invention. Figure 3 This is a third-view overall structural diagram of a meropenem precision infusion control device adapted to different pathogens, provided in an embodiment of the present invention. Figure 4 A schematic diagram of the control board structure of a meropenem precision infusion control device adapted to different pathogens provided in an embodiment of the present invention; Figure 5 This invention provides a meropenem precision infusion control device adapted to different pathogens. Figure 4Enlarged view of point A; Figure 6 This is a schematic diagram of the second limiting cylinder structure of a meropenem precision infusion control device adapted to different pathogens provided in an embodiment of the present invention; Figure 7 This is a schematic diagram of the first limiting cylinder structure of a meropenem precision infusion control device adapted to different pathogens provided in an embodiment of the present invention; Figure 8 A schematic diagram of the reservoir structure of a meropenem precision infusion control device adapted to different pathogens provided in an embodiment of the present invention; Figure 9 This is a schematic diagram of the travel plate structure of a meropenem precision infusion control device adapted to different pathogens provided in an embodiment of the present invention; Figure 10 A schematic diagram of the permanent magnet column structure of a meropenem precision infusion control device adapted to different pathogens provided in an embodiment of the present invention; Figure 11 A schematic diagram of the liquid-driven plate structure of a meropenem precision infusion control device adapted to different pathogens provided in an embodiment of the present invention; Figure 12 A schematic diagram of the side plate groove structure of a meropenem precision infusion control device adapted to different pathogens provided in an embodiment of the present invention; Figure 13 This invention provides a meropenem precision infusion control device adapted to different pathogens. Figure 12 Enlarged view of point B; Figure 14 A schematic diagram of the liquid guide tube structure of a meropenem precision infusion control device adapted to different pathogens provided in an embodiment of the present invention; Figure 15 This is a schematic diagram of the limiting head structure of a meropenem precision infusion control device adapted to different pathogens, provided in an embodiment of the present invention. Figure 16 This is a schematic diagram of the gripper structure of a meropenem precision infusion control device adapted to different pathogens, provided as an embodiment of the present invention.

[0018] Explanation of reference numerals in the attached figures: In the diagram: 1. Rear shell; 2. Front shell; 3. Push rod; 4. Push box; 5. Traveling component; 501. Travel plate; 502. End sealing plate; 503. Travel guide rod; 504. Guide rod; 505. Side slide plate; 506. Side slide block; 507. Drive plate; 508. Travel groove; 509. Travel slider; 5010. Spring ring; 5011. Travel spring; 5012. Permanent magnet column; 5013. Sensing hole; 5014. Sensing shell; 5015. Sensing element. 6. Coil; 601. Liquid drive component; 602. Liquid drive plate; 603. Liquid bladder; 604. First movable hole; 605. Extension tube; 606. Second movable hole; 607. Extension rod; 608. Side plate groove; 609. Liquid drive side plate; 6010. Liquid guide tube; 6011. Stroke guide hole; 6012. Guide hole; 6013. Mounting hole; 6014. First connecting pipe; 7. Power component; 701. Liquid storage box; 702. First micro diaphragm pump; 7 03. Second miniature diaphragm pump; 704. Support; 705. Dispensing box; 706. First suction pipe; 707. First supply pipe; 708. First miniature diaphragm solenoid valve; 709. Second suction pipe; 7010. Second supply pipe; 7011. Second miniature diaphragm solenoid valve; 7012. Second connecting pipe; 7013. Third miniature diaphragm solenoid valve; 7014. Coriolis microflow meter; 8. Clamping component; 801. First limiting cylinder; 802. Limiting groove 803. Limiting head; 804. Second limiting cylinder; 805. Pulling rod; 806. Clamping spring; 807. Clamping head; 808. Rotating rod; 809. Gripper; 8010. Transmission gear; 8011. Torsion spring; 8012. Positioning plate; 8013. Tightening rod; 8014. Abutting block; 8015. Torsion wheel; 9. Mounting slot; 10. Positioning slot; 11. Display screen; 12. Button group; 13. Adjustment knob; 14. Control board; 15. Foot plate. Detailed Implementation

[0019] Exemplary embodiments of the invention will now be described in more detail with reference to the accompanying drawings. While exemplary embodiments of the invention are shown in the drawings, it should be understood that the invention may be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this invention will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.

[0020] like Figures 1 to 16As shown, an embodiment of the present invention provides a meropenem precision infusion control device adapted to different pathogens, comprising: a rear shell 1 and a front shell 2 disposed at the front end of the rear shell 1, further comprising: a push rod 3, slidably inserted into the front shell 2; a push box 4, fixed to one end of the push rod 3 extending out of the front shell 2; a stroke member 5, fixed inside the front shell 2; a liquid drive member 6, slidably disposed on the stroke member 5; a power member 7, fixed to the inner bottom of the rear shell 1 and the front shell 2; a clamping member 8, slidably inserted into the front shell 2; two mounting slots 9, the two mounting slots 9 being formed on the front shell 2; a locking slot 10, formed on the mounting slot 9; further comprising: a display screen 11, fixed above the front shell 2; a button group 12, fixed above the front shell 2; an adjustment knob 13, rotatably disposed on the front shell 2; a control board 14, fixed inside the top of the front shell 2; and a foot plate 15, fixed below the rear shell 1 and the front shell 2.

[0021] Two stroke plates 501 are provided, both fixed to the front housing 2; end sealing plates 502 are fixed to both ends of the stroke plates 501; four stroke guide rods 503 are provided, each fixed to the end sealing plate 502; two guide rods 504 are provided, both fixed to both sides of the end sealing plate 502; side slide plates 505 are fixed to both sides of the stroke plates 501; side slide seats 506 are slidably mounted on the side slide plates 505; a drive plate 507 is fixed to the side slide seats 506 from below; multiple liquid drive plates 601 are provided, each slidably mounted on the stroke guide rods 503; and a bladder groove 602. The following components are provided: a liquid drive plate 601; a liquid bladder 603 fixed in a bladder groove 602; a first movable hole 604 on the liquid drive plate 601; an extension tube 605 slidably disposed in the first movable hole 604; a second movable hole 606 on the extension tube 605; an extension rod 607 slidably disposed in the first movable hole 604; a side plate groove 608 on both sides of the liquid drive plate 601; two liquid drive side plates 609, both fixed on the extension rod 607 and located in the side plate groove 608; and a liquid guide tube 6010 fixed on the liquid drive plate 601, with one end of the tube extending into the liquid bladder 603.

[0022] Specifically, the travel component 5 forms a rigid support frame with the end cap 502 via two travel plates 501. The travel plates 501 are fixed to the inner wall of the front shell 2 by bolts or by medical-grade environmentally friendly adhesive. The end cap 502 is fixed to both ends of the travel plates 501 by medical-grade environmentally friendly adhesive to ensure that the frame as a whole is not loose or shifted. The four travel guide rods 503 and the two guide rods 504 are all inserted into the pre-set through holes in the end cap 502 with an interference fit, and the ends are reinforced with threaded lock nuts to provide smooth and jam-free sliding for the multiple liquid drive plates 601. The track, side slide plate 505 and stroke plate 501 are integrally injection molded, and the side slide seat 506 and the bottom of the drive plate 507 are bonded and fixed with medical environmentally friendly adhesive; the liquid drive side plate 609 is bonded and fixed to the extension rod 607 with medical high strength adhesive and embedded in the side plate groove 608. The liquid guide tube 6010 and the liquid drive plate 601 are connected by heat fusion sealing. The interface between the tube body and the liquid bladder 603 is tightly sealed with medical silicone sealing sleeve. Connecting the liquid bladder 603 realizes the medium transmission between the liquid bladder 603 and the outside, laying a sealed and stable foundation for subsequent feed transmission.

[0023] In another preferred embodiment of the present invention, the travel member 5 further includes: a travel groove 508, formed on the travel plate 501; a travel slider 509, slidably disposed in the travel groove 508, and fixed above on one end of the push rod 3 extending into the front housing 2; a spring ring 5010, fixed on one end of the push rod 3 extending into the front housing 2; and a travel spring 5011, one end fixed in the front housing 2, the other end fixed on the spring ring 5010, and sleeved on the push rod 3.

[0024] The stroke component 5 also includes: a permanent magnet column 5012, fixed on both sides of the stroke slider 509; a sensing hole 5013, opened inside the stroke plate 501; a sensing shell 5014, fixed inside the sensing hole 5013; and a sensing coil 5015, fixed inside the sensing shell 5014.

[0025] Specifically, when the stroke slider 509 slides along the stroke groove 508, it synchronously drives the push rod 3 to extend and retract. The top of the stroke slider 509 and the end of the push rod 3 are bonded and fixed with medical-grade environmentally friendly adhesive to prevent disengagement during sliding. The stroke spring 5011 provides the push rod 3 with a rebound force through the spring ring 5010. The spring ring 5010 and the push rod 3 are connected by a sliding sleeve. The two ends of the stroke spring 5011 are respectively welded to the inner wall of the front shell 2 and the spring ring 5010, making disassembly and maintenance convenient. When the permanent magnet column 5012 moves with the stroke slider 509, the induction coil 5015 senses the change in the magnetic field to collect the stroke position information in real time. The permanent magnet column 5012 and the stroke slider 509 are fixed by an embedded adhesive. The induction shell 5014 and the induction hole 5013 are bonded and fixed with medical-grade environmentally friendly adhesive. After the induction coil 5015 is wound, it is fixed inside the induction shell 5014 by potting with insulating glue to ensure that the feed accuracy is controllable throughout the process.

[0026] In another preferred embodiment of the present invention, the liquid drive component 6 further includes: a stroke guide hole 6011, which is formed on the four sides of the liquid drive plate 601 and slidably sleeved on the stroke guide rod 503; a guide hole 6012, which is formed on both sides of the liquid drive plate 601 and slidably sleeved on the guide rod 504; a mounting hole 6013, which is formed on the liquid drive plate 601; and a first connecting pipe 6014, one end of which is fixedly inserted into the mounting hole 6013 and the other end of which is sleeved on the liquid guide pipe 6010.

[0027] Specifically, the liquid drive plate 601 is fitted with the stroke guide rod 503 and the guide rod 504 through the stroke guide hole 6011 and the guide hole 6012 respectively. The inner walls of the stroke guide hole 6011 and the guide hole 6012 are smooth and polished. The hole body and the corresponding guide rod are fitted with clearance to ensure that no radial displacement occurs during the sliding process. The first pair of connecting pipes 6014 is fixed and connected to the liquid guide tube 6010 through the mounting hole 6013. The first pair of connecting pipes 6014 and the mounting hole 6013 are double sealed with an interference fit and a sealing gasket. The connection between the connecting pipe and the liquid guide tube 6010 is reinforced with a medical hose clamp to achieve stable communication between the external medium and the liquid bladder 603, prevent glycerin leakage, and ensure that the filling and discharging operation of the liquid bladder 603 is completely sealed and accurate.

[0028] In another preferred embodiment of the present invention, the power component 7 includes: a liquid storage box 701, fixed inside the rear shell 1 and the front shell 2; a first micro diaphragm pump 702, fixed inside the rear shell 1; a second micro diaphragm pump 703, fixed inside the rear shell 1; a support 704, fixed inside the front shell 2; a dispensing box 705, fixed on the support 704; a first suction pipe 706, one end fixed to the liquid storage box 701 and the other end fixed to the first micro diaphragm pump 702; and a first supply pipe 707, one end fixed... One end of the first micro diaphragm pump 702 is fixed to the other end of the dispensing box 705; the first micro diaphragm solenoid valve 708 is fixed to the first supply pipe 707; the second suction pipe 709 is fixed to the dispensing box 705 at one end and to the second micro diaphragm pump 703 at the other end; the second supply pipe 7010 is fixed to the second micro diaphragm pump 703 at one end and to the storage box 701 at the other end; the second micro diaphragm solenoid valve 7011 is fixed to the second supply pipe 7010.

[0029] The power unit 7 also includes: a second pair of connecting pipes 7012, fixed on the dispensing box 705; a third miniature diaphragm solenoid valve 7013, fixed on the end of the second pair of connecting pipes 7012 near the dispensing box 705; and a Coriolis micro flow meter 7014, fixed on the end of the second pair of connecting pipes 7012 away from the dispensing box 705.

[0030] Specifically, the reservoir 701 stores the transmission medium glycerol. Both the reservoir 701 and the dispensing container 705 are threadedly fastened inside the housing. The support 704 is welded to the inner wall of the front housing 2, and the dispensing container 705 is welded to the support 704. The first micro diaphragm pump 702 and the second micro diaphragm pump 703 are both bolted to the inner wall of the rear housing 1 via pump body mounting brackets. The first micro diaphragm pump 702 supplies glycerol to the dispensing container 705 through the first suction pipe 706 and the first supply pipe 707, while the second micro diaphragm pump 703 achieves glycerol reflux through the second suction pipe 709 and the second supply pipe 7010. All interfaces between the infusion lines and the pump body and reservoir are sealed with threads and PTFE tape to prevent media leakage. The third miniature diaphragm solenoid valve 7013 is fixed to the second connector 7012 by threaded connection to control the opening and closing of a single second connector 7012. The Coriolis micro flow meter 7014 is threaded and sealed to the end of the second connector 7012 to detect the media flow in real time to accurately control the filling and discharging volume of the liquid bladder 603. The first connector 6014 and the second connector 7012 are connected by a delivery hose. The two ends of the delivery hose are quick-connect fittings to the corresponding connectors for modular disassembly and replacement.

[0031] In another preferred embodiment of the present invention, the clamping member 8 includes: a first limiting cylinder 801, fixed inside the front shell 2; a limiting groove 802, formed on the first limiting cylinder 801; a limiting head 803, slidably disposed inside the limiting groove 802; a second limiting cylinder 804, fixed outside the front shell 2; a pulling rod 805, one end fixed to the limiting head 803, and the other end extending out of the second limiting cylinder 804; a clamping spring 806, one end fixed to the limiting head 803, and the other end fixed inside the front shell 2, and located inside the first limiting cylinder 801; and a clamping head 807, fixed to one end of the pulling rod 805 extending out of the second limiting cylinder 804, and slidably connected to the second limiting cylinder 804.

[0032] The clamping component 8 also includes: two rotating rods 808, located within the same push box 4, with one end of each rotating rod 808 rotatably mounted within the push box 4 and the other end of each rotating rod 808 extending out of the push box 4; two grippers 809, located on the same push box 4, with each gripper 809 fixed to the end of the rotating rod 808 extending out of the push box 4; two transmission gears 8010, located within the same push box 4, with each transmission gear 8010 fixed to the rotating rod 808 and located within the push box 4, and the two transmission gears 8010 meshing with each other; and two torsion springs 8011, located within the same push box 4, with one end of each torsion spring 8011 fixed within the push box 4 and the other end of each torsion spring 8011 fixed to the transmission gear 8010.

[0033] The clamping component 8 also includes: a positioning plate 8012, fixed on the rear shell 1; a tightening rod 8013, threaded on the positioning plate 8012; a stop block 8014, fixed on one end of the tightening rod 8013 located inside the positioning plate 8012; and a torsion wheel 8015, fixed on the end of the tightening rod 8013 away from the stop block 8014.

[0034] Specifically, the first limiting cylinder 801 and the second limiting cylinder 804 are both integrally injection molded or welded to the front shell 2, resulting in a stable and deformation-free structure. The limiting head 803 slides along the limiting groove 802, driving the pull rod 805 to extend and retract. The ends of the limiting head 803 and the pull rod 805 are welded together. The two ends of the clamping spring 806 are respectively clamped to the limiting head 803 and the inner wall of the front shell 2, driving the clamping head 807 to clamp the syringe in the mounting groove 9. The rotating rod 808 and the push box 4 are rotatably connected by bearings. The clamping claw 809 and the rotating rod 808 are bolted together. The transmission gear 8010 is welded to the rotating rod 808. The two transmission gears... Engaging 8010 causes the rotating rod 808 to rotate synchronously, driving the gripper 809 to open and close to limit the syringe core rod; the two ends of the torsion spring 8011 are welded and fixed to the limiting post on the inner wall of the push box 4 and the side of the transmission gear 8010, respectively, providing a stable restoring force for the gripper 809; the positioning plate 8012 is bolted to the rear shell 1, the tightening rod 8013 is precision threaded to the positioning plate 8012, the abutment block 8014 is integrally formed with the tightening rod 8013, and the torsion wheel 8015 is tightly bonded to the tightening rod 8013. Rotating the torsion wheel 8015 causes the tightening rod 8013 to drive the abutment block 8014 to press against the infusion bracket, thus achieving a stable fixation of the entire device.

[0035] Traditional micro-infusion pumps rely on mechanical connections such as lead screw drives, gear meshing, and piston sliding engagement for core transmission. After long-term use, issues like thread wear, gear tooth surface wear, and piston jamming frequently occur. Furthermore, syringe adapters often use rigid slots, only compatible with a single syringe size. Replacing adapter parts requires thread disassembly or complete replacement, making the process cumbersome. In clinical infection treatment, different pathogens exhibit significant differences in antibiotic sensitivity. Meropenem, as a broad-spectrum carbapenem antibiotic, shows a high correlation between efficacy and blood drug concentration. Traditional intravenous infusion methods cannot effectively manage drug delivery. Intraoperative dosage adjustments are difficult to match with pathogen resistance or changes in patient pharmacokinetics, often resulting in insufficient or excessive medication, which affects treatment efficacy and may even increase the risk of adverse reactions. More importantly, traditional methods cannot be adapted to different syringe models, making it difficult to select the appropriate drug volume based on patient weight and infection severity. This device, through its clamping structure and modular design of the liquid capsule, enables adjustable meropenem infusion, maintaining the optimal drug concentration in the body, and is compatible with various syringe models, providing precise, efficient, and safe anti-infective treatment for different pathogen infections.

[0036] This device can be placed on a desktop or fitted onto an infusion stand via the mounting plate 8012. A one-to-one connection between the first pair of connecting tubes 6014 and the second pair of connecting tubes 7012 is used to deliver glycerin. The reservoir 701, dispensing box 705, and bladder 603 are all filled with glycerin. Multiple bladders 603 are provided, employing a modular design. Each bladder 603, when filled with glycerin, bulges to a uniform width of 5mm. By controlling the volume of glycerin extracted from the bladder 603, the degree of bladder contraction controls the feed rate of the syringe via the push rod 3 and push box 4, thus regulating the speed and dosage of the medication entering the body and maintaining body temperature. The internal blood drug concentration is stable. For the three commonly used 10ml, 20ml, and 50ml syringe models in clinical practice, the device presets different adaptation parameters through the control board 14. When a single liquid balloon 603 is fully contracted, the feed stroke of the push rod 3 is fixed at 2mm, corresponding to the output of a quantitative drug solution for different syringe models: when adapted to a 10ml syringe, the feed stroke can push the syringe to output 0.5ml of drug solution; when adapted to a 20ml syringe, it outputs 1ml of drug solution; and when adapted to a 50ml syringe, it outputs 2.5ml of drug solution. This modular design can quickly switch model parameters through the button group 12 to meet the needs of different clinical scenarios.

[0037] Before this device can be used, the following preparatory steps must be completed: First, select the appropriate syringe model using the display screen 11 and button group 12. The device will automatically match the corresponding fluid bladder 603 contraction parameters and glycerin extraction threshold. Then, start the fluid bladder 603 filling program to fill all fluid bladders 603 with glycerin, extending the push rod 3 and push box 4 to their maximum length. Next, rotate the torsion wheel 8015. The rotation of the torsion wheel 8015 will cause the tightening rod 8013 to screw into the locking plate 8012. The tightening rod 8013 will cause the stop block 8014 to firmly press against the infusion stand. Pull the clamping head 807. The clamping head 807 moves along the outer side of the second limiting cylinder 804, synchronously driving the pull rod 805 to move. The pull rod 805 drives the limiting head 803 to slide within the first limiting cylinder 801, compressing the clamping spring 806. Regardless of whether a 10ml, 20ml, or 50ml syringe is selected, the limiting head 803 can slide flexibly within the limiting groove 802, adapting to syringe barrels of different diameters. The clamping spring 806 can automatically adjust the elastic clamping force according to the syringe size, avoiding excessive clamping that could damage the syringe or excessive looseness that could cause displacement. The syringe is placed in the mounting slot 9, and the syringe barrel lugs are inserted into the locking slot 10. The clamping head 807 is released, and the clamping head 807 returns to its original position under the elastic force of the clamping spring 806, clamping the syringe and firmly fixing it in the mounting slot 9. Control is performed via the display screen 11 and button group 12. The control board 14, according to the preset syringe model parameters, drives the push rod 3 and push box 4 to slowly retract until the push box 4 moves to the syringe plunger. The gripper 809 is moved, causing the gripper 809 to swing and drive the rotating rod 808 to rotate. The rotation of the rotating rod 808 drives... The transmission gear 8010 rotates and meshes with another transmission gear 8010. The other transmission gear 8010 drives the corresponding rotating rod 808 and gripper 809 to swing. During the rotation of the transmission gear 8010, the torsion spring 8011 is twisted. After the gripper 809 is released, the torsion spring 8011 drives the rotating rod 808 and gripper 809 to reset. The gripper 809 can automatically adjust the clamping angle according to the size of the syringe rod tail end, further restricting the syringe rod tail end, preventing rod displacement, and achieving stable positioning of syringe rods of different models.

[0038] The procedure for filling all the liquid sacs 603 with glycerin is as follows: The first micro diaphragm pump 702, the first micro diaphragm solenoid valve 708, and all the third micro diaphragm solenoid valves 7013 are activated; the first micro diaphragm pump 702 draws glycerin from the storage tank 701 through the first extraction tube 706; the glycerin flows through the first micro diaphragm pump 702 and is injected into the first supply tube 707, then flows from the first supply tube 707 into the distribution box 705; after flowing out of the distribution box 705, the glycerin passes through the second pair of... Connector 7012, delivery hose, first pair of connectors 6014, and liquid guide tube 6010 enter the liquid bladder 603, causing all liquid bladders 603 to inflate. The inflated liquid bladders 603 push the hydraulic drive side plate 609 against the outer sides of the hydraulic drive plate 601. The hydraulic drive side plate 609 drives the extension cylinder 605 to extend from the first movable hole 604, and the extension rod 607 extends through the second movable hole 606 of the extension cylinder 605. The extension lengths of the hydraulic drive side plate 609, the extension cylinder 605, and the extension rod 607 are all subject to... Due to structural limitations, multiple bulging liquid bladders 603 drive the liquid drive plates 601 to slide on the stroke guide rods 503 and guide rods 504, causing the multiple liquid drive plates 601 to separate from each other on the stroke guide rods 503 and guide rods 504; the multiple bulging liquid bladders 603 push the push rod 3 and push box 4 to extend; the bulging liquid bladders 603 push the liquid drive side plate 609, the liquid drive side plate 609 pushes the drive plate 507 to move, and the drive plate 507 slides on the side slide plate 505 through the side slide seat 506. The drive plate 507 pushes the stroke slider 509 to move, and the stroke slider 509 slides in the stroke groove 508. The stroke slider 509 drives the push rod 3 to extend out of the rear shell 1 and the front shell 2. The push rod 3 compresses the stroke spring 5011 through the spring ring 5010. Finally, the push rod 3 and the push box 4 extend to the working position. When the permanent magnet column 5012 moves with the stroke slider 509, the induction coil 5015 senses the change of the magnetic field to collect the stroke position information in real time, so as to ensure the control of feed accuracy.

[0039] After the syringe is fixed in the mounting slot 9 and the locking slot 10, adjust the push rod 3 and the push box 4 to retract into the rear shell 1 and the front shell 2 until the push box 4 reaches the end of the syringe rod.

[0040] When the syringe is pushed to output the drug solution, the second micro diaphragm pump 703 and the second micro diaphragm solenoid valve 7011 are activated. According to the preset syringe model parameters, the control board 14 only opens the third micro diaphragm solenoid valve 7013 corresponding to a single liquid drive plate 601 and liquid bladder 603. The retraction stroke distance of a single liquid drive plate 601 and liquid bladder 603 after drawing glycerin directly controls the push rod 3 and push box 4 to push the drug solution feed of the syringe, ensuring that the output drug solution volume meets the single liquid bladder control standard of this model of syringe.

[0041] The specific drug delivery process is as follows: The second micro diaphragm pump 703 draws glycerin from the dispensing box 705 through the second extraction pipe 709. The dispensing box 705 draws glycerin from the corresponding liquid sac 603 in the liquid drive plate 601 through the opened single third micro diaphragm solenoid valve 7013, the second connecting pipe 7012, the delivery hose, the first connecting pipe 6014, and the guide pipe 6010. The glycerin flows back to the storage box 701 through the second micro diaphragm pump 703 and the second supply pipe 7010. After the glycerin in the liquid sac 603 decreases, under the rebound force of the stroke spring 5011, the liquid drive side plates 609 on both sides of the liquid drive plate 601 move closer to the side plate groove 608. The extension rod 607 of the liquid drive side plate 609... The extension tube 605 retracts into the first movable hole 604, thereby shortening the thickness of the bulging liquid bladder 603. The amount of glycerol drawn by the second micro diaphragm pump 703 is detected in real time by the Coriolis micro flow meter 7014, and the detection data is synchronously transmitted to the control board 14. The control board 14 compares the data with the preset syringe model threshold. When the detected glycerol outflow reaches the corresponding threshold, it indicates that the liquid bladder 603 has contracted to the set stroke, the liquid drive side plate 609 is completely inserted into the side plate groove 608, the corresponding third micro diaphragm solenoid valve 7013 is closed, and at the same time, another third micro diaphragm solenoid valve 7013 is immediately opened to continue drawing glycerol from the next bulging liquid bladder 603.

[0042] Using a single bulging sac 603 as a unit of length, the length of the sac 603 is shortened by drawing out the amount of glycerol inside, which in turn drives the push rod 3 and the push box 4 to push the syringe to output a quantitative amount of drug solution. The output volume of a single sac of drug solution for different syringe models is precisely matched by preset parameters on the control board 14 without the need for additional replacement of mechanical parts. The injection rate of the syringe is further precisely controlled by the time it takes for the second micro diaphragm pump 703 to draw out the glycerol inside a single sac 603. For example, when using a 10ml syringe, the time to draw out the glycerol from a single sac 603 is set to 1 minute to achieve an infusion rate of 0.5ml / min. When using a 50ml syringe, the time to draw out the glycerol is set to 30 seconds to achieve an infusion rate of 5ml / min, meeting the drug administration rate requirements for different pathogen infections and achieving a stable maintenance of blood drug concentration in the human body.

[0043] The second micro diaphragm pump 703 draws glycerol from the liquid capsules 603 one by one. Under the rebound force of the stroke spring 5011, multiple liquid-driven plates 601 slide on the stroke guide rod 503 and guide rod 504, and the overall length of the multiple liquid-driven plates 601 gradually shortens. Through the above series of linked actions, the device can flexibly adapt to various syringe models of 10ml, 20ml and 50ml. Through the modular quantitative control and rate adjustment of a single liquid capsule 603, the device can achieve adjustable infusion of meropenem for patients, so as to maintain the optimal concentration of the drug in the body, thereby providing precise, efficient and safe anti-infective treatment for different pathogens.

[0044] The above description represents the preferred embodiments of the present invention. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A meropenem precision infusion control device adapted to different pathogens, comprising: The rear shell and the front shell disposed at the front end of the rear shell are characterized in that they further include: A push rod is slidably inserted into the front housing; a push box is fixed to one end of the push rod extending out of the front housing; a stroke component is fixed inside the front housing; a hydraulic drive component is slidably mounted on the stroke component; a power component is fixed to the inner bottom of the rear housing and the front housing; a clamping component is slidably inserted into the front housing; two mounting slots are provided, and the two mounting slots are formed on the front housing; a locking slot is formed on the mounting slot. There are two stroke plates, both of which are fixed to the front shell; end sealing plates are fixed to both ends of the stroke plates; four stroke guide rods are provided, each of which is fixed to the end sealing plate; two guide rods are provided, both of which are fixed to both sides of the end sealing plate; side slide plates are fixed to both sides of the stroke plates; side slide seats are slidably mounted on the side slide plates; and a drive plate is fixed to the side slide seats from below. Multiple liquid-driven plates are provided, and each liquid-driven plate is slidably mounted on a travel guide rod; a bladder groove is formed inside the liquid-driven plate; a liquid bladder is fixed inside the bladder groove; a first movable hole is formed on the liquid-driven plate; an extension cylinder is slidably mounted inside the first movable hole; a second movable hole is formed inside the extension cylinder; an extension rod is slidably mounted inside the first movable hole; side plate grooves are formed on both sides of the liquid-driven plate; two liquid-driven side plates are provided, and both liquid-driven side plates are fixed on the extension rod and located inside the side plate groove; a liquid guide tube is fixed on the liquid-driven plate, and one end of the tube extends into the liquid bladder.

2. The meropenem precision infusion control device adapted to different pathogens according to claim 1, characterized in that, The travel component also includes: A travel groove is formed on the travel plate; a travel slider is slidably set in the travel groove and fixed above on one end of the push rod extending into the front housing; a spring ring is fixed on one end of the push rod extending into the front housing; a travel spring is fixed at one end in the front housing and at the other end on the spring ring and sleeved on the push rod.

3. The meropenem precision infusion control device adapted to different pathogens according to claim 2, characterized in that, The travel component also includes: The permanent magnet column is fixed on both sides of the stroke slider; the sensing hole is opened inside the stroke plate; the sensing shell is fixed inside the sensing hole; and the sensing coil is fixed inside the sensing shell.

4. The meropenem precision infusion control device adapted to different pathogens according to claim 1, characterized in that, The hydraulic drive component also includes: The stroke guide holes are opened on the four sides of the liquid drive plate and are slidably sleeved on the stroke guide rods; the guide holes are opened on both sides of the liquid drive plate and are slidably sleeved on the guide rods; the mounting holes are opened on the liquid drive plate; the first pair of pipes are fixedly inserted into the mounting holes at one end and sleeved on the liquid guide pipe at the other end.

5. The meropenem precision infusion control device adapted to different pathogens according to claim 1, characterized in that, The power component includes: A liquid storage box is fixed inside the rear and front shells; a first micro diaphragm pump is fixed inside the rear shell; a second micro diaphragm pump is fixed inside the rear shell; a support is fixed inside the front shell; a dispensing box is fixed on the support; a first suction pipe is fixed at one end to the liquid storage box and at the other end to the first micro diaphragm pump; a first supply pipe is fixed at one end to the first micro diaphragm pump and at the other end to the dispensing box; a first micro diaphragm solenoid valve is fixed on the first supply pipe; a second suction pipe is fixed at one end to the dispensing box and at the other end to the second micro diaphragm pump; a second supply pipe is fixed at one end to the second micro diaphragm pump and at the other end to the liquid storage box; a second micro diaphragm solenoid valve is fixed on the second supply pipe.

6. The meropenem precision infusion control device adapted to different pathogens according to claim 5, characterized in that, The power component also includes: The second pair of connectors is fixed to the separatory box; the third miniature diaphragm solenoid valve is fixed to the end of the second pair of connectors near the separatory box; and the Coriolis microflow meter is fixed to the end of the second pair of connectors away from the separatory box.

7. The meropenem precision infusion control device adapted to different pathogens according to claim 1, characterized in that, The clamping element includes: The first limiting cylinder is fixed inside the front housing; the limiting groove is formed on the first limiting cylinder; the limiting head is slidably disposed in the limiting groove; the second limiting cylinder is fixed on the outside of the front housing; the pull rod has one end fixed to the limiting head and the other end extending out of the second limiting cylinder; the clamping spring has one end fixed to the limiting head and the other end fixed inside the front housing and located inside the first limiting cylinder; the clamping head is fixed on one end of the pull rod extending out of the second limiting cylinder and is slidably connected to the second limiting cylinder.

8. The meropenem precision infusion control device adapted to different pathogens according to claim 7, characterized in that, The clamping element further includes: Two rotating rods are provided within the same push box, with one end of each rod rotatably mounted inside the push box and the other end extending out of the push box; two grippers are provided on the same push box, with each gripper fixed to the end of the rotating rod extending out of the push box; two transmission gears are provided within the same push box, with each transmission gear fixed to the rotating rod and located inside the push box, and the two transmission gears meshing with each other; two torsion springs are provided within the same push box, with one end of each torsion spring fixed inside the push box and the other end fixed to the transmission gear.

9. The meropenem precision infusion control device adapted to different pathogens according to claim 8, characterized in that, The clamping element further includes: The locking plate is fixed to the rear shell; the tightening rod is threaded onto the locking plate; the stop block is fixed to the end of the tightening rod located inside the locking plate; and the torsion wheel is fixed to the end of the tightening rod away from the stop block.

10. The meropenem precision infusion control device adapted to different pathogens according to claim 1, characterized in that, Also includes: The display screen is fixed to the top of the front cover; The button assembly is fixed on the top of the front cover; the adjustment knob is rotated and located on the front cover; the control panel is fixed inside the top of the front cover. Foot pads are fixed to the bottom of the rear and front shells.

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