Pressure rise time automatic adjustment method and device, and storage medium
By monitoring the patient's ventilation flow and airway pressure in real time, and automatically adjusting the ventilator's pressure rise time, the problem of increased workload and inability to dynamically match patient needs in existing technologies is solved, achieving greater comfort and safety.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- BEIJING AEONMED
- Filing Date
- 2025-12-30
- Publication Date
- 2026-05-29
AI Technical Summary
The current ventilator settings for pressure rise time require manual adjustment, which increases the workload of clinicians and cannot dynamically match changes in the patient's inspiratory needs, affecting patient comfort and patient-ventilator synchrony.
By monitoring the patient's proximal ventilation flow and airway pressure in real time, the system determines the pressure rise rate based on the logic of peak pressure and pressure-time integral, automatically adjusts the pressure rise time, optimizes the pressure rise rate, and avoids pressure overshoot.
It reduces the workload of medical staff, dynamically responds to patients' breathing needs, improves human-ventilator synchronization and ventilation comfort and safety, and is suitable for multiple ventilation modes.
Smart Images
Figure CN122097767A_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of general medical equipment technology, and particularly relates to a method, device and storage medium for automatic adjustment of pressure rise time. Background Technology
[0002] The typical pressure waveform for pressure-controlled inflation and pressure support inflation is a square wave. Its characteristic is that once inspiration is triggered (or the ventilator starts inflation), the inspiratory valve opens fully, and the ventilation pressure rapidly increases from the baseline level to the set target pressure. At this time, the pressure difference between the peak pressure and the alveolar pressure is the largest, and the flow rate is the highest. Subsequently, as the inspiratory time increases, the alveolar pressure increases, the pressure difference gradually decreases, and the flow rate drops rapidly. Therefore, the flow rate is represented by a decreasing wave.
[0003] In patients with significantly elevated airway resistance or rapid, deep breathing, a decreasing flow wave can easily satisfy their craving for high flow, especially high flow at the beginning of inspiration, and alleviate respiratory distress. However, if the patient's airway resistance is basically normal and breathing is relatively stable, and the ventilator is performing well, then the ventilation resistance to be overcome is lower, the synchronization time is significantly shortened, and the rapidly rising high-speed airflow can irritate the face (in non-invasive positive pressure ventilation) or trachea (in artificial airway ventilation), reducing compliance and even inducing irritative conjunctivitis or frequent coughing.
[0004] To control the rate of pressure rise and influence the flow distribution during the initial inspiratory phase, many ventilators are currently set with different inspiratory pressure rise times to meet varying ventilation needs. Pressure rise time refers to the time it takes for the patient's airway pressure to rise from its initial value to the target pressure value set by the ventilation device during ventilation. Taking ventilators as an example, there are three typical ways to set the pressure rise time: the first is to set a fixed time; the second is to set the pressure rise time as a certain percentage of the inspiratory time; and the third is to set the pressure rise time using different levels, each with a corresponding rise time.
[0005] However, the above setup method has the following shortcomings: 1. Manual adjustment increases the workload of clinicians. The pressure rise time should be individualized based on the patient's lung characteristics. Currently, physicians must manually adjust the pressure rise time according to the patient's respiratory mechanics to find a suitable ventilation protocol, increasing the clinical workload.
[0006] 2. The fixed rise time cannot be adjusted to match the dynamic changes in the patient's inspiratory needs. This may result in the flow rate being too high or too low, thus affecting the patient's inspiratory comfort.
[0007] 3. Changes in lung mechanics affect patient-ventilator synchrony. In clinical practice, patients' conditions change, and the pressure rise time should be automatically adjusted according to changes in the patient's lung characteristics. This is because the same pressure rise time may be too short for patients with low lung compliance and too long for patients with increased lung compliance. Summary of the Invention
[0008] The purpose of this invention is to overcome the defects of the prior art and to propose an automatic adjustment method, device and storage medium for pressure rise time.
[0009] In view of this, the present invention proposes an automatic pressure rise time adjustment method for medical ventilation equipment, comprising: Step 1: Monitor the patient's proximal ventilation flow and airway pressure in real time during the current ventilation cycle; Step 2: In pressure control or pressure support mode, based on the inspiratory flow waveform and airway pressure waveform of the current inspiratory cycle, determine whether the pressure rise rate is appropriate based on the logic of peak pressure and the logic of pressure-time integral, respectively. Step 3: Based on the judgment results, dynamically adjust the pressure rise time of the next ventilation cycle to optimize the pressure rise rate and avoid pressure overshoot.
[0010] As an improvement to the above method, step 2, based on the logic of peak pressure, determines whether the pressure rise rate is appropriate. Specifically, this includes: in the early stage of inhalation, if the measured peak airway pressure of the current inhalation cycle is lower than the target pressure value, it is determined that the pressure rise is too slow; if the peak pressure is a set multiple of the target pressure value or the peak pressure exceeds the target pressure value and reaches a first threshold, it is determined that the pressure rise is too fast; the target pressure value is the sum of the set inhalation pressure value and PEEP.
[0011] As an improvement to the above method, step 2, based on the logic of pressure-time integration, determines whether the pressure rise rate is appropriate. Specifically, this includes: in the early stage of inhalation, if the time integral of the measured airway pressure in the current inhalation cycle is lower than the time integral of the expected pressure signal, then the pressure rise is determined to be too slow; if the time integral of the measured airway pressure is a set multiple of the time integral of the expected pressure signal, then the pressure rise is determined to be too fast.
[0012] As an improvement to the above method, the dynamic adjustment in step 3 includes: When the pressure rise rate is determined to be too slow, shorten the set value of the pressure rise time for the next ventilation cycle. When the pressure rise rate is determined to be too fast, the set value for the pressure rise time of the next ventilation cycle is extended.
[0013] As an improvement to the above method, the adjustment of the pressure rise time includes adjusting the step size and range value.
[0014] As an improvement to the above method, when the logic based on peak pressure and the logic based on pressure time integration conflict with each other, the logic based on peak pressure is used for dynamic adjustment.
[0015] As an improvement to the above method, the method further includes: determining the inflation type of the current ventilation cycle before step 1; and recording the current pressure rise time setting value as an initial reference value only in pressure control or pressure support ventilation mode, and then executing steps 1 to 3.
[0016] As an improvement to the above method, the dynamic adjustment in step 3 is performed based on the initial reference value; when the dynamic adjustment ends, the set value of the pressure rise time is restored to the initial reference value.
[0017] In a second aspect, the present invention provides an automatic pressure rise time adjustment device, comprising: Flow measurement equipment is used to monitor the proximal ventilation flow of patients in real time; Pressure measurement equipment used to monitor the proximal airway pressure of patients in real time; Processor, configured to perform the automatic pressure rise time adjustment method as described in any one of claims 1 to 8; and Memory is used to store program instructions and data.
[0018] On the other hand, the present invention provides a computer-readable storage medium having a computer program stored thereon, which, when executed by a processor, implements the above-described automatic pressure rise time adjustment method.
[0019] Compared with the prior art, the advantages of the present invention are: 1. This invention uses the inspiratory flow waveform and airway pressure waveform based on the current inspiratory cycle, and uses logic based on peak pressure and logic based on pressure-time integral, respectively, to determine whether the pressure rise rate is suitable for automatic adjustment, thereby reducing the operational burden on medical staff. 2. Dynamically respond to changes in the patient's respiratory needs, improve patient-ventilator synchrony, reduce respiratory discomfort, and ensure the safety and comfort of clinical ventilation; 3. Based on the pressure accumulation effect and overshoot, the pressure rise time is automatically fine-tuned to match the inspiratory flow rate with the patient's breathing needs, avoiding pressure overshoot or insufficient rise, and improving ventilation comfort and safety. 4. It is applicable to multiple ventilation modes and has good clinical applicability. Attached Figure Description
[0020] Figure 1 This is a flowchart of the automatic pressure rise time adjustment method of the present invention. Detailed Implementation
[0021] In both pressure-controlled and pressure-supported ventilation types, the system performs dynamic monitoring and evaluation during the Tslope time period within each inspiratory cycle to support the implementation of automatic adjustment mechanisms. This process mainly includes two core calculations: 1. Pressure integral calculation: The airway pressure during the Tslope time period is integrated to reflect the cumulative effect of pressure over time; 2. Peak pressure calculation: Record the maximum airway pressure reached during Tslope.
[0022] At the start of each inhalation, the current Tslope value is adjusted based on the pressure integral and maximum airway pressure result from the previous cycle, according to the following logic: 1. If the peak pressure is lower than the target pressure level (the target pressure is the sum of the set inspiratory pressure and PEEP: Pinsp or Psupp + PEEP), the pressure delivery in this cycle is considered insufficient. In one embodiment, the Tslope time is shortened in 50ms increments: Pinsp is the total pressure in pressure control mode, Psupp is the additional pressure in pressure support mode, and PEEP: Positive End-Expiratory Pressure.
[0023] 2. If the peak pressure is higher than the target pressure by a set multiple, which is 1.02 times in one embodiment, or exceeds the target pressure to reach a first threshold, which is +0.5 cmH2O in one embodiment, it is considered that the pressure rise rate is too fast and may cause overshoot. In one embodiment, the Tslope time is extended in 50ms increments.
[0024] If none of the above conditions are met, it indicates that there is no significant pressure overshoot or insufficient pressure level. In this case, further consideration should be given to adjusting the pressure rise time based on the pressure-time integral, and analyzing the inspiratory flow waveform: 1. If the airway pressure integral of the current cycle is less than the expected pressure integral value, it is considered that the pressure delivery in this cycle is too slow. In one embodiment, the Tslope time is shortened in 50ms increments. 2. If the airway pressure integral of the current cycle is a set multiple of the desired pressure integral, such as 1.02 times, it is considered that the pressure delivery in this cycle is too fast. In one embodiment, the Tslope time is shortened in 50ms increments. If the logic based on maximum airway pressure and the logic based on pressure-time integral conflict with each other, i.e., the two logics adjust in opposite directions, then the value determined by the logic based on maximum airway pressure shall be used as the final value.
[0025] The upper and lower limits of the integral error that trigger the adjustment, the upper and lower limits of the difference between the maximum inhalation pressure that triggers the adjustment and the pressure set value, and the Tslope adjustment step size are not strictly constrained.
[0026] This automatic adjustment mechanism, through periodic feedback and fine-tuning, enables the system to adapt to changes in lung compliance and respiratory needs of different patients without the need for frequent clinical intervention.
[0027] The technical solution of the present invention will be described in detail below with reference to the accompanying drawings and embodiments.
[0028] Example 1 like Figure 1 As shown, this embodiment of the invention provides an automatic adjustment method for pressure rise time (Tslope), applied to medical ventilation equipment, the method comprising: 1. Monitor the patient's proximal ventilation flow and airway pressure during the current ventilation cycle using flow measurement and pressure measurement devices; 2. In pressure control or pressure support ventilation mode, determine whether the current pressure rise is appropriate based on the changing characteristics of the inspiratory flow waveform and airway pressure waveform of the current inspiratory cycle, and dynamically adjust Tslope. 3. During the ventilation cycle, the Tslope is finely adjusted cycle by cycle based on the monitoring results of the previous cycle and the patient's ventilation characteristics to optimize the pressure rise rate and avoid pressure overshoot.
[0029] In the above method, the method further includes: Determine the inflation type of the current ventilation cycle and enable the Tslope automatic adjustment function only in pressure control or pressure support modes; suspend adjustment calculations for other ventilation modes. Record the Tslope setting value before enabling automatic adjustment as an initial reference to limit the range of changes in automatic adjustment, and restore the original value after turning off automatic adjustment.
[0030] In the above method, the step of adjusting Tslope based on the variation characteristics of inspiratory flow waveform and airway pressure waveform includes: 1. When the pressure rise rate is too slow, the Tslope can be shortened appropriately. In one embodiment, the Tslope time is shortened in 50ms increments to make the pressure rise faster. 2. When the pressure rise rate is too fast, the Tslope is extended appropriately. In one embodiment, the Tslope time is extended in 50ms increments to make the pressure rise more gradual.
[0031] In the above method, the determination of whether the pressure rise rate is too fast or too slow can be based on the following logic: (1) Based on the logic of peak pressure, determine whether the pressure rise rate is appropriate, specifically including: During the initial stage of inhalation, if the measured peak airway pressure of the current inhalation cycle is lower than the target pressure value, the pressure rise is determined to be too slow; if the peak pressure is 1.02 times the target pressure value or the peak pressure exceeds the target pressure value by 0.5 cmH2O, the pressure rise is determined to be too fast; the target pressure value is the sum of the set inhalation pressure value and PEEP.
[0032] (2) Based on the logic of pressure time integral, determine whether the pressure rise rate is appropriate, specifically including: in the early stage of inhalation, if the time integral of the measured airway pressure of the current inhalation cycle is lower than the time integral of the expected pressure signal, it is determined that the pressure rise is too slow; if the time integral of the measured airway pressure is 1.02 times the time integral of the expected pressure signal, it is determined that the pressure rise is too fast.
[0033] If the logic based on maximum airway pressure and the logic based on pressure-time integral conflict with each other, i.e., the two logics adjust in opposite directions, then the value determined by the logic based on maximum airway pressure shall be used as the final value.
[0034] The initial inhalation phase can be a preset fixed time or the current pressure rise time. Adjusting the step size and range requires consideration of safety factors.
[0035] Example 2 Embodiment 2 of the present invention provides an automatic pressure rise time adjustment device, comprising: Flow measurement equipment is used to monitor the proximal ventilation flow of patients in real time; Pressure measurement equipment used to monitor the proximal airway pressure of patients in real time; Processor, for executing the automatic pressure rise time adjustment method as described above; and Memory is used to store program instructions and data.
[0036] Example 3 Embodiment 3 of the present invention provides a computer-readable storage medium having a computer program stored thereon, which, when executed by a processor, implements the automatic adjustment method for pressure rise time as described above.
[0037] Experimental data: Test 1: A comparative test was conducted between the present invention and existing technologies regarding pressure rise time. The specific test results are shown in Table 1. Clearly, the present invention outperforms the existing technology in terms of pressure rise speed. Whether in the 0-65% or 0-95% range of the target pressure, the present invention exhibits a faster pressure response capability, enabling it to establish the inspiratory pressure plateau more promptly. Furthermore, its pressure rise characteristics show a good match with the set value of the Tslope (inspiratory slope) parameter, reflecting its faster pressure control performance.
[0038] From the perspective of the inspiratory flow rate waveform, the peak inspiratory flow rate of this invention is lower than that of existing technologies, exhibiting a more gradual rise. This characteristic makes the inspiratory process gentler than existing technologies, and is expected to bring a more comfortable patient experience in clinical applications, especially suitable for patients who are sensitive to airway stimulation or have high requirements for ventilation comfort.
[0039] Table 1. Record of Test Results for Comparison of Pressure Rise Time
[0040]
[0041] Test 2: With the automatic pressure rise adjustment function enabled, the pressure rise time using the method of this invention is shorter than that of the prior art in all use cases. The pressure rise of the prior art generally exhibits a "fast at the beginning and slow at the end" pressure rise pattern. In all use cases, the peak inhalation flow rate of this invention is higher than that of the prior art, as shown in Table 2.
[0042] Table 2 Comparison of peak inspiratory flow rates
[0043] Based on the comparative test results of automatic adjustment of pressure rise time, the method of the present invention exhibits faster pressure tracking capability in the latter half of the pressure rise, and establishes the inspiratory pressure platform in a shorter time.
[0044] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail with reference to the embodiments, those skilled in the art should understand that modifications or equivalent substitutions to the technical solutions of the present invention do not depart from the spirit and scope of the technical solutions of the present invention, and all such modifications or substitutions should be covered within the scope of the claims of the present invention.
Claims
1. An automatic pressure rise time adjustment method for medical ventilation equipment, comprising: Step 1: Monitor the patient's proximal ventilation flow and airway pressure in real time during the current ventilation cycle; Step 2: In pressure control or pressure support mode, based on the inspiratory flow waveform and airway pressure waveform of the current inspiratory cycle, determine whether the pressure rise rate is appropriate based on the logic of peak pressure and the logic of pressure-time integral, respectively. Step 3: Based on the judgment results, dynamically adjust the pressure rise time of the next ventilation cycle to optimize the pressure rise rate and avoid pressure overshoot.
2. The automatic pressure rise time adjustment method according to claim 1, characterized in that, In step 2, the logic based on peak pressure determines whether the pressure rise rate is appropriate. Specifically, this includes: at the beginning of inhalation, if the measured peak airway pressure of the current inhalation cycle is lower than the target pressure value, it is determined that the pressure rise is too slow; if the peak pressure is a set multiple of the target pressure value or the peak pressure exceeds the target pressure value and reaches the first threshold, it is determined that the pressure rise is too fast; the target pressure value is the sum of the set inhalation pressure value and PEEP.
3. The automatic pressure rise time adjustment method according to claim 2, characterized in that, In step 2, the logic based on pressure-time integration determines whether the pressure rise rate is appropriate. Specifically, this includes: in the early stage of inhalation, if the time integral of the measured airway pressure in the current inhalation cycle is lower than the time integral of the expected pressure signal, then the pressure rise is determined to be too slow; if the time integral of the measured airway pressure is a set multiple of the time integral of the expected pressure signal, then the pressure rise is determined to be too fast.
4. The automatic pressure rise time adjustment method according to claim 2 or 3, characterized in that, The dynamic adjustment in step 3 includes: When the pressure rise rate is determined to be too slow, shorten the set value of the pressure rise time for the next ventilation cycle. If the pressure rise rate is determined to be too fast, the set value for the pressure rise time of the next ventilation cycle is extended.
5. The automatic pressure rise time adjustment method according to claim 4, characterized in that, The adjustment of the pressure rise time includes adjusting the step size and range value.
6. The automatic pressure rise time adjustment method according to claim 4, characterized in that, When the logic based on peak pressure and the logic based on pressure time integration conflict with each other, the logic based on peak pressure is used for dynamic adjustment.
7. The automatic pressure rise time adjustment method according to claim 1, characterized in that, The method further includes: determining the inflation type of the current ventilation cycle before step 1; and recording the current pressure rise time setting value as the initial reference value only in pressure control or pressure support ventilation mode, and then executing steps 1 to 3.
8. The automatic pressure rise time adjustment method according to claim 7, characterized in that, The dynamic adjustment in step 3 is performed based on the initial reference value; when the dynamic adjustment ends, the set value of the pressure rise time is restored to the initial reference value.
9. An automatic pressure rise time adjustment device, characterized in that, include: Flow measurement equipment is used to monitor the proximal ventilation flow of patients in real time; Pressure measurement equipment used to monitor the proximal airway pressure of patients in real time; Processor, configured to perform the automatic pressure rise time adjustment method as described in any one of claims 1 to 8; and Memory is used to store program instructions and data.
10. A computer-readable storage medium having a computer program stored thereon, characterized in that, When the computer program is executed by the processor, it implements the automatic adjustment method for pressure rise time as described in any one of claims 1 to 8.