一种高通量全自动液-液逆流微萃取系统

By combining array-type countercurrent microextraction with a fluid dynamic unit design, the problem of low mass transfer efficiency and extraction rate in existing microextraction technologies has been solved, realizing efficient and automated liquid-liquid countercurrent extraction. This breakthrough overcomes the bottleneck of traditional microextraction and is applicable to pharmaceutical, biomedical testing, and environmental monitoring.

CN122098039BActive Publication Date: 2026-07-17LIAONING HUIKANG TESTING & EVALUATING TECH CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
LIAONING HUIKANG TESTING & EVALUATING TECH CO LTD
Filing Date
2026-04-28
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing microextraction technologies have limitations in terms of mass transfer efficiency and extraction rate. In particular, countercurrent microextraction systems are complex, costly, and have poor stability, making it difficult to meet the requirements for efficient separation and miniaturization.

Method used

A high-throughput fully automated liquid-liquid countercurrent microextraction system was designed, which adopts an array-type countercurrent microextraction combination, combining a filtration unit, a countercurrent microextraction unit and a fluid power unit. The liquid is discharged through a capillary to form tiny droplets and countercurrent flow, which increases the liquid-liquid contact area and time, and achieves efficient mass transfer.

Benefits of technology

It achieves high-throughput, automated liquid-liquid countercurrent extraction, significantly improving extraction recovery and reproducibility. It has a compact structure, low cost, and is suitable for laboratory automation platforms, with mass transfer efficiency improved by more than 20 times.

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Abstract

本发明属于微流控化学分析与分离技术领域,具体涉及一种高通量全自动液‑液逆流微萃取系统,包括若干逆流微萃取组合,每个逆流微萃取组合包括抽滤单元、逆流微萃取单元和流体动力单元;多个逆流微萃取单元实现多通道同步萃取,抽滤单元集成过滤与负压循环,完成样品前处理,流体动力单元由抽气泵、多组蠕动泵、多个毛细接头构成全自动流路,实现萃取过程全流程无人值守。本发明通过萃取管内重相向下、轻相滴状上浮的逆向交错流动强化传质,具有高通量、自动化程度高、萃取效率高、结构紧凑、重现性好等优点,适用于食品、环境、医药、生物检测等复杂样品中微量成分的高效富集与分离。
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