Application of a biological metabolism marker combination in detection of sow pregnancy
By detecting anserine and histamine in sow feces, the problems of early, convenient, and non-invasive detection of sow pregnancy have been solved, achieving highly accurate pregnancy diagnosis. Anserine and histamine, as a key metabolite combination, significantly improve the specificity and sensitivity of the detection.
CN122108986APending Publication Date: 2026-05-29SOUTH CHINA AGRICULTURAL UNIVERSITY
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Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SOUTH CHINA AGRICULTURAL UNIVERSITY
- Filing Date
- 2026-01-29
- Publication Date
- 2026-05-29
AI Technical Summary
Technical Problem
Existing technologies make it difficult to achieve early, convenient, and non-invasive methods for detecting pregnancy in sows, and the composition of fecal metabolites is complex, with individual metabolites showing unstable changes.
Method used
A combination of biomarkers, including anserine and histamine, was used to detect the levels of metabolites in sow feces using spectroscopic, immunological, and precision instrumental analysis methods. The expression differences of anserine and histamine were used to determine pregnancy status.
Benefits of technology
It provides a highly accurate and sensitive method for early pregnancy diagnosis. The combined use of goose muscle peptide and histamine significantly improves the specificity and sensitivity of the test.
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Figure CN122108986A_ABST
Abstract
The present application relates to the field of biological detection and livestock breeding technology, and particularly relates to application of a biological metabolism marker combination in sow pregnancy detection. The present application confirms that carnosine and / or histamine can be used as a metabolism marker for early pregnancy diagnosis of sows through non-targeted metabolomics detection and analysis on sow excrement. The expression levels of metabolites carnosine and histamine in the excrement of pregnant sows and non-pregnant sows are significantly different. Specifically, the level of metabolite carnosine in the excrement of pregnant sows is significantly higher than that in the excrement of non-pregnant sows, and the level of metabolite histamine is significantly lower. The combined use of the two metabolites has good sensitivity and specificity, and can be used for early pregnancy detection of sows with high accuracy.
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