一株非解乳糖链球菌及其在制备抗沙门氏菌感染制剂中的应用

By providing probiotic preparations and feed additives made from non-lactose-degrading streptococci, and utilizing their indirect immunomodulatory effects, the lack of research on the anti-Salmonella infection effects of non-lactose-degrading streptococci in the existing technology has been addressed, achieving effective prevention and treatment of Salmonella infection and alleviating weight loss.

CN122128190BActive Publication Date: 2026-07-17SOUTH CHINA AGRICULTURAL UNIVERSITY

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SOUTH CHINA AGRICULTURAL UNIVERSITY
Filing Date
2026-05-07
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

There is a lack of research on the effects of non-lactose-degrading streptococci on Salmonella infection, especially regarding their effects on systemic infection load and weight loss in the host, and the effectiveness of antibiotics in preventing Salmonella infection is limited.

Method used

A strain of non-lactolytic streptococcus (CCTCC NO: M 2026565) is provided for the preparation of probiotic preparations, feed additives and veterinary preparations for the prevention or treatment of Salmonella typhimurium infection, which enhance the host's resistance through indirect immunomodulatory effects.

Benefits of technology

It effectively alleviates weight loss caused by Salmonella infection, reduces tissue damage, lowers the pathogen load in the liver and spleen, and enhances the host's resistance to Salmonella.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明涉及微生物技术领域,特别涉及一株非解乳糖链球菌及其在制备抗沙门氏菌感染制剂中的应用。本发明提供了一株非解乳糖链球菌,所述非解乳糖链球菌(Streptococcus alactolyticus)于2026年3月30日保藏于中国典型培养物保藏中心,保藏编号为CCTCC NO:M 2026565。宿主在提前灌胃所述非解乳糖链球菌后,对鼠伤寒沙门氏菌的抵抗能力有明显提高。宿主感染鼠伤寒沙门氏菌后体重下降缓慢,并且肝脏和脾脏的鼠伤寒沙门氏菌量受到抑制,降低宿主病原菌负荷。
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