Use of aloe vera extract for the preparation of sting inhibitors and for the preparation of a medicament for the prevention or treatment of inflammatory bowel disease

Abstract

The application relates to the technical field of medicines, in particular to the use of Euphorbia thymifolia extract for preparing a STING inhibitor and for preparing a medicine for preventing or treating inflammatory bowel disease. The application finds that Euphorbia thymifolia extract and EHTA and EA contained in the Euphorbia thymifolia extract can be used as a STING inhibitor to inhibit the activation of a STING signal pathway, inhibit the secretion of proinflammatory cytokines and inflammatory factors, and can be used for preventing or treating STING-mediated related diseases. The Euphorbia thymifolia extract and EHTA and EA contained in the Euphorbia thymifolia extract can especially improve the colon injury of inflammatory bowel disease, such as ulcerative colitis and Crohn's disease, and are used for preventing or treating inflammatory bowel disease.

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