一种金纳米花SERS基底及其制备方法和应用
By growing gold nanoflower arrays in situ on aluminum foil, the problems of complex preparation, high cost and poor stability of existing SERS substrates are solved. High-density hot spot distribution and low-cost large-area preparation are achieved, which is suitable for rapid and simple detection of bacteria and drug-resistant enzymes.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- HUAZHONG AGRI UNIV
- Filing Date
- 2026-05-08
- Publication Date
- 2026-07-17
AI Technical Summary
Existing SERS substrates are complex to prepare, costly, and difficult to prepare in large-area reproducible fabrications. Furthermore, the substrates have poor stability and uncontrollable hotspot distribution, which affects the reproducibility of detection results.
Using aluminum foil as a substrate, gold nanoflower arrays are grown in situ on the substrate after the surface oxide film is removed by etching. The spontaneous displacement reaction of chloroauric acid simplifies the preparation process, reduces costs, and enables large-area reproducible preparation.
The preparation process is simple and easy to operate, with low cost. It forms a high-density and uniformly distributed hot spot on the substrate surface, which has excellent Raman signal enhancement ability. It is suitable for label-free bacterial detection and five types of carbapenemase detection. The detection process is simple and efficient, and the results are stable and reliable.
Smart Images
Figure CN122142340B_ABST