一种基于生成式同异学习与原型引导的CT图像域适应肺结节分类方法、介质及设备

By employing generative similarity-dissimilarity learning and prototype-guided methods, a lung nodule classification model was constructed. This solved the problem of CT data distribution offset in cross-domain applications, achieving accurate lung nodule classification and type differentiation in different domains, and improving the generalization ability and accuracy of the classification model.

CN122156825BActive Publication Date: 2026-07-17SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING
Filing Date
2026-05-06
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

When existing technologies are applied across domains, the distribution offset of CT data leads to a decrease in the accuracy of deep learning-based automatic classification of lung nodules. Furthermore, manually set pixel-domain geometric transformations are difficult to generate effective semantic information, affecting the accuracy and consistency of lung nodule classification.

Method used

We employ generative similarity-dissimilarity learning and prototype-guided methods. By training with generative similarity-dissimilarity learning and guiding with prototype labels, we construct a lung nodule classification model. We use the generative model to interpolate in the feature space to generate semantically invariant similar samples, and learn the classification ability of the target domain through self-supervised learning.

Benefits of technology

It achieves accurate classification of pulmonary nodules in different domains, reduces annotation costs, improves cross-domain generalization ability, can accurately distinguish nodule types, and has strong clinical application value.

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Abstract

本发明公开了一种基于生成式同异学习与原型引导的CT图像域适应肺结节分类方法、介质及设备,属于图像处理的技术领域,获取源域的配对样本并有监督训练肺结节分类模型。然后,获取目标域的样本,对肺结节分类模型,交替进行生成式同异学习训练以及原型标签引导的分类训练,直至特征提取器和分类头收敛,得到最优肺结节分类模型,以实现有效的目标域分类能力学习。最后,将待处理的CT图像输入最优肺结节分类模型进行肺结节分类。本发明通过在生成式模型的特征空间进行插值,生成具有语义不变性的增强视图,并以自监督的方式让分类模型学习辨别语义相同样本和语义不同样本的能力,从而更有效地获得可泛化到不同域的特征表示能力。
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