Lactobacillus plantarum strains having the ability to decompose histamine

By using the Lactobacillus plantarum strain KBL20066, which does not produce biogenic amines, the allergy problem caused by probiotic products has been solved. Histamine degradation and prevention or treatment of allergic reactions have been achieved, providing probiotic products and functional foods that do not produce biogenic amines.

CN122161919APending Publication Date: 2026-06-05KO BIOLABS INC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
KO BIOLABS INC
Filing Date
2024-09-24
Publication Date
2026-06-05

AI Technical Summary

Technical Problem

Existing probiotic products may produce histamine, leading to allergic reactions, and existing antihistamines require continuous use and cannot completely solve the problem of histamine-induced allergies.

Method used

The strain of *Lactobacillus plantarum* KBL20066 with accession number KCTC 15615BP was used. This strain does not produce biogenic amines, has histamine degradation ability, is acid-resistant and bile-resistant, and can colonize and degrade histamine in the digestive system.

Benefits of technology

It effectively prevents or treats allergic reactions caused by histamine, reduces the occurrence of allergic reactions, provides probiotic products that do not produce biogenic amines, and is a functional food that degrades histamine.

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Abstract

The present application relates to Lactobacillus plantarum strains having the ability to degrade histamine.
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