网织纤维染色病理图像智能分割方法及其应用

By constructing an appearance-structure dual-stream cross-attention network and a boundary-aware dynamic loss mechanism, the problem of insufficient explicit modeling of the topological destruction mode of woven fiber networks in existing technologies is solved, and accurate identification and efficient segmentation of the invasion boundary of pituitary neuroendocrine tumors are achieved.

CN122176704BActive Publication Date: 2026-07-17SHENZHEN SHENGQIANG TECH

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHENZHEN SHENGQIANG TECH
Filing Date
2026-05-11
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing computer-aided analysis techniques cannot effectively model the topology of reticular fiber networks, resulting in insufficient accuracy in identifying the invasion boundaries of pituitary neuroendocrine tumors. Furthermore, existing segmentation methods cannot balance global continuity and microscopic boundary quality when processing ultra-high resolution images.

Method used

A dual-stream cross-attention network based on appearance and structure is constructed. By combining boundary-aware dynamic loss and counterintuitive graph model, and through multi-stage pre-classification filtering and physical scale-driven boundary awareness mechanism, the network can accurately capture fiber topological structure damage and finely optimize the boundary.

Benefits of technology

It improves the accuracy of tumor invasion boundary identification, generates segmentation results with high clinical sharpness and spatial closure, reduces computational costs, improves diagnostic efficiency, eliminates splicing artifacts, and provides reliable quantitative analysis basis.

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Abstract

本发明提出了一种网织纤维染色病理图像智能分割方法及其应用,针对现有技术难以识别网状纤维结构破坏以界定肿瘤边界及滑窗导致伪影的问题,本发明对图像进行自适应滑窗切分与多阶段前置过滤提取有效图像块;输入双流网络,通过基于组织物理尺寸映射感受野的结构流与外观流进行交叉注意力融合,实现对外观异常与结构破坏的协同验证;模型训练采用含物理尺度约束的动态边界感知损失项进行联合优化;最后通过空间权重融合机制与结合物理先验的图模型消除断裂伪影并平滑全局边界。本发明主要用于实现垂体神经内分泌肿瘤的高保真病灶分割。
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