一种银耳多糖微粒及其制备方法

By combining the synergistic degradation of composite enzymes and the synergistic stabilization of composite stabilizers with the regulation of polyethylene glycol, tremella polysaccharide microparticles with uniform particle size, high stability and excellent antioxidant properties were prepared. This solved the problems of uncontrollable particle size and poor stability in the existing technology, and improved bioavailability and application effect.

CN122182491BActive Publication Date: 2026-07-17THE WEST CHINA SECOND UNIV HOSPITAL OF SICHUAN

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
THE WEST CHINA SECOND UNIV HOSPITAL OF SICHUAN
Filing Date
2026-05-13
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

In existing technologies, the particle size of Tremella polysaccharides is uncontrollable and the stability is poor, which limits bioavailability and application effects.

Method used

By utilizing the synergistic degradation of composite enzymes, the synergistic stabilization of composite stabilizers, and the dual function of polyethylene glycol, tremella polysaccharide microparticles with an average particle size in the range of 200 nm to 500 nm, uniform distribution, and high stability were prepared.

Benefits of technology

This method achieves controllable particle size, high stability, and excellent antioxidant properties in Tremella polysaccharide microparticles, thereby improving bioavailability and application effects.

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Abstract

本发明提供了一种银耳多糖微粒及其制备方法,属于生物技术领域。它是由多糖含量不低于70%w / w的银耳水提取物为原料,经复合酶酶解处理得到银耳多糖酶解液,再与复合稳定剂混合均匀,加入聚乙二醇,制备成微粒;本发明还提供了银耳多糖微粒的制备方法。本发明通过复合酶的协同降解、复合稳定剂的协同稳定以及聚乙二醇的双重功能与关键工艺顺序的有机结合,成功制备出平均粒径可控制在200 nm至500 nm范围内、分布均匀且稳定性高的银耳多糖微粒,在食品、医药及化妆品领域具有广阔的应用前景。
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