一种超分子干凝胶手性SERS传感材料及其制备方法与应用
By preparing supramolecular dry gels formed by the self-assembly of imidazole-functionalized amphiphilic compounds containing aromatic cores, the stability and reproducibility problems of chiral molecule analysis in existing SERS technology have been solved, achieving high SERS activity and sensitive enantiomer recognition in the same material.
CN122188224BActive Publication Date: 2026-07-17SHANDONG UNIV
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SHANDONG UNIV
- Filing Date
- 2026-05-13
- Publication Date
- 2026-07-17
Smart Images
Figure CN122188224B_ABST
Abstract
本发明属于表面增强拉曼散射检测和手性分子识别技术领域，涉及一种超分子干凝胶手性SERS传感材料及其制备方法与应用。所述材料以C8Ph2imi、C8Ph4imi、C8indole2imi或C8indole4imi为前驱体，经过碱性溶液去质子化、超声分散、pH调控诱导溶胶‑凝胶转变以及干燥处理，得到具有三维纳米纤维网络结构的超分子干凝胶。该材料通过氢键作用、π‑π堆积作用、疏水相互作用及pH诱导的超分子重构形成手性限域微环境，可用于手性小分子的SERS识别。以C8indole4imi为代表，材料在不同pH条件下对布洛芬对映体表现出不同识别偏好，能够实现pH调控的手性识别切换。该材料有助于减少对贵金属基底和外加手性选择剂的依赖。
Need to check novelty before this filing date? Find Prior Art
Citation Information
Patent Citations
Supramolecular gelator of gemini type structure and preparation method of supramolecular gelator
CN106366033A
Hydrogel dressing for chronic wound surface of diabetes mellitus as well as preparation method and application of hydrogel dressing
CN120899992A