A method and system for optimizing preservation of immune cell activity with cryopreservation solution components

By collecting data on the material properties of cryopreservation solution components, analyzing the wear and tear of preparation equipment and process conditions, and optimizing the cryopreservation solution components, the problem of insufficient accuracy in existing cryopreservation solution component optimization methods has been solved, and efficient preservation of immune cells has been achieved.

CN122266567APending Publication Date: 2026-06-23HEBEI BAILING CELL BIOTECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HEBEI BAILING CELL BIOTECHNOLOGY CO LTD
Filing Date
2026-02-04
Publication Date
2026-06-23

AI Technical Summary

Technical Problem

Existing methods for optimizing cryopreservation solution components lack systematic analysis, making it difficult to predict synergistic or antagonistic effects between components. The impact of equipment status and process fluctuations is difficult to control, resulting in the difficulty in reproducing cryopreservation solution quality in large-scale production. Furthermore, relying on terminal cell viability evaluation cannot fully reflect the impact of each step in the preparation process on cell function.

Method used

By collecting property data of cryopreservation solution components, analyzing the wear and tear of preparation equipment, obtaining process condition data of cryopreservation solution, and performing cell sampling, the cryopreservation solution components are optimized to improve preservation effect by combining effect characteristics, storage performance and process preservation quality.

Benefits of technology

This improved the accuracy of cryopreservation solution component optimization, ensuring the preservation quality of immune cells and their subsequent application effects, and enhancing the comprehensiveness and accuracy of the preparation process.

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Abstract

The application relates to the field of artificial intelligence technology and discloses a method and system for optimizing the storage of immune cell activity of a cryopreservation solution, which comprises the following steps: obtaining component materials corresponding to the cryopreservation solution and preparation equipment, collecting material attribute data corresponding to the component materials, analyzing the effect characteristics of the component materials on the activity of immune cells in the storage process, analyzing the equipment wear degree of the preparation equipment, evaluating the storage performance of the preparation equipment, collecting process working condition data corresponding to the cryopreservation solution in the preparation process, calculating the freezing accuracy of the cryopreservation solution, performing cell sampling treatment on the cryopreservation solution in the preparation process to obtain a process freezing sample, evaluating the cell activity of the process freezing sample to obtain multivariate activity data, evaluating the process storage quality corresponding to the preparation process, and performing component optimization processing on the cryopreservation solution to obtain an optimization result. The application can improve the accuracy of the component optimization of the cryopreservation solution.
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