A PCR instrument hot lid device
By combining automated adjustment and pressure regulation modules, the sealing problem between the PCR instrument's hot cap device and PCR tubes of different specifications was solved, achieving precise alignment and uniform sealing between the hot cap and the PCR tube, thus improving the stability and accuracy of PCR experiments.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- HANGZHOU BOHENG TECH CO LTD
- Filing Date
- 2026-04-09
- Publication Date
- 2026-06-30
AI Technical Summary
The existing PCR instrument heating caps are incompatible with different sizes of PCR tubes during use, resulting in poor sealing. Operation relies on manual experience, which can easily lead to improper fit, abnormal local pressure, and affect the stability and accuracy of experimental results.
A PCR instrument hot cap device was designed, which uses a pressure equalization component and a linkage displacement component to achieve automatic adjustment of the hot cap. Combined with a pressure regulating module and a temperature sensing adjustment module, it ensures precise alignment and uniform sealing between the hot cap and the PCR tube. The downward pressure is adjusted by a buffer bolt and a support spring, and temperature uniformity is achieved by integrating a detection probe and a temperature regulating resistor.
It achieves precise alignment and uniform sealing between the hot cap and the PCR tube, improving the stability and accuracy of PCR experiments, avoiding experimental failures caused by operational errors and local condensation, and ensuring the stability of heat transfer and sealing effect.
Smart Images
Figure CN122303027A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the technical field of PCR instruments, specifically a PCR instrument heating cover device. Background Technology
[0002] As a core functional component of a polymerase chain reaction (PCR) instrument, the heating cap's structural design and performance directly determine the stability, reproducibility, and accuracy of PCR experiments, making it a crucial foundation for ensuring the smooth conduct of PCR reactions. PCR reactions require multiple high-temperature cycles of denaturation, annealing, and extension. The heating cap's primary function is to maintain a high temperature by ensuring close contact with the PCR reaction tube cap, thus inhibiting the evaporation of liquid reagents in the reaction system. Simultaneously, it prevents condensation from forming on the inner wall of the cap, avoiding uneven reaction concentrations, decreased amplification efficiency, or even experimental failure caused by condensation dripping back down.
[0003] Currently, PCR experiments require compatibility with reaction tubes of different sizes and heights. Therefore, the heating cap needs to be highly adjustable, apply uniform downward pressure, and avoid excessive pressure that could deform the reaction tubes. Existing PCR instrument heating caps rely heavily on manual pushing or opening / closing, and their effectiveness depends entirely on the operator's experience. Inexperienced operators cannot guarantee a tight seal and uniform pressure, leading to problems such as inadequate fit and abnormal local pressure. This not only weakens the anti-evaporation and anti-condensation performance but also easily triggers hidden "intermittent condensation," disrupting the heat transfer stability between the reaction tubes and the sample stage. Even with advanced PCR instruments, improper operation often results in poor experimental results or even failure. The lack of a reliable locking mechanism also makes the cap prone to positional shifts during experiments, reducing sealing and heat transfer efficiency. Therefore, it is necessary to design a PCR instrument heating cap device that can press and seal PCR tubes of different sizes, increasing the accuracy and stability of PCR experiments. Summary of the Invention
[0004] The purpose of this invention is to provide a PCR instrument heating cover device to solve the problems mentioned in the background art.
[0005] To achieve the above objectives, the present invention provides the following technical solution: A PCR instrument hot cover device includes a hot cover bottom shell, a hot cover fixing plate, and a hot cover fixing frame. A flat pressure assembly for adjusting the hot cover bottom shell up and down is provided between the hot cover bottom shell and the hot cover fixing plate. The flat pressure assembly includes a vertical motor that is vertically connected to the hot cover fixing plate. A horizontal gear is provided at the power output end of the vertical motor. A vertical rack that is fixed to the hot cover bottom shell is meshed on one side of the horizontal gear. A plurality of support cylinders supporting the vertical rack are provided on the top of the hot cover bottom shell for pressing and sealing PCR tubes of different sizes. Both ends of the hot cover fixing plate are provided with linkage displacement components for driving horizontal movement. The linkage displacement components include a pair of guide rods fixed in parallel in the hot cover fixing frame. Sliders that slide on the guide rods are fixed on both sides of the hot cover fixing plate for precise alignment of the hot cover with the PCR instrument.
[0006] Preferably, the transverse gear is rotated by a vertical motor, the top of the multiple supporting cylinders is provided with the same plate, the vertical rack is movably connected to the heat cover fixing plate, and the vertical rack adjusts the height of the heat cover bottom shell through the transverse gear for locking and sealing the PCR instrument.
[0007] Preferably, the inner side of the slider is provided with ball bearings that fit against the guide rod frame to improve the smoothness of the horizontal movement of the heat cover fixing plate.
[0008] Preferably, the linkage displacement assembly further includes a pair of horizontal motors fixedly mounted on the hot cover fixing frame. The hot cover fixing frame is provided with two pairs of synchronous pulley shafts aligned and parallel to the guide rod frame, and the end of each synchronous pulley shaft is connected to a horizontal motor. The same belt body is sleeved on the outside of each pair of synchronous pulley shafts, and the belt body is fixedly connected to the slider. The hot cover fixing frame is provided with a belt pressure plate for limiting the belt body, which is used for stable driving of the horizontal movement of the hot cover bottom shell.
[0009] Preferably, a connecting plate is clamped at the lower end of the pressure-regulating component, and multiple pressure-regulating modules are disposed through the connecting plate. The lower end of the pressure-regulating module is vertically connected to the bottom shell of the heat cover for pressure regulation and sealing of the PCR instrument by the heat cover.
[0010] Preferably, the pressure regulating module includes a buffer bolt that penetrates through the connecting plate. A support spring is sleeved on the outside of the buffer bolt and abuts against the connecting plate and the bottom shell of the hot cover. Both the inner and outer sides of the support spring are fitted with rubber sleeves. A compression ring is provided at the lower end of the support spring. An annular detection seat is provided on the bottom shell of the hot cover for the buffer bolt to pass through, and the compression ring is sleeved on the outside of the annular detection seat. Several point-like detection ends are provided on the top of the annular detection seat. The lower end of the buffer bolt is threaded to the bottom shell of the hot cover for stable pressing of the hot cover against the PCR instrument.
[0011] Preferably, the lower surface of the heat-sealing bottom shell is provided with several temperature-sensing adjustment modules for temperature detection and localized heating of the PCR instrument by the heat-sealing.
[0012] Preferably, the temperature sensing adjustment module includes a temperature measuring chamber formed on the bottom shell of the hot cover, a detection probe is provided in the middle of the temperature measuring chamber, the detection probe is located on the lower surface of the bottom shell of the hot cover that contacts the PCR tube, and a temperature regulating resistor is sleeved inside the temperature measuring chamber, the temperature regulating resistor having an arc-shaped structure.
[0013] Preferably, the lower end of the hot cover bottom shell is provided with an edge sealing frame, and the surface of the edge sealing frame is provided with a plurality of fitting movable parts, the lower end of the fitting movable parts extending to the middle of the edge sealing frame, for sealing the hot cover with PCR instruments of different specifications.
[0014] Compared with the prior art, the beneficial effects of the present invention are: 1. In this invention, the use of the flat pressure component and the linkage displacement component together allows for adaptive vertical height adjustment of the hot cap, pressing down and sealing PCR tubes of different sizes, locking the hot cap to the PCR instrument, stably and smoothly replacing traditional manual operation, ensuring the accuracy of hot cap alignment, guaranteeing the fit and seal between the hot cap and the PCR tube, and increasing the accuracy of PCR experiments. 2. This invention sets up multiple pressure regulating modules between the flat pressure component and the bottom shell of the hot cover, consisting of buffer bolts, support springs, fitting rubber sleeves, and annular detection seats. The buffer bolts and support springs work together to achieve adaptive adjustment of the pressure of the hot cover. The annular detection seat and the compression ring are used to accurately measure the pressure. The rubber sleeve reduces friction between components and protects the springs, preventing excessive pressure from deforming the PCR tube. This ensures the uniformity of the pressure exerted by the hot cover on the PCR tube and further improves the sealing and heat transfer effect. 3. In this invention, a temperature sensing and adjustment module consisting of a temperature measuring chamber, a detection probe, and an arc-shaped temperature regulating resistor is integrated into the bottom shell of the hot cover to achieve real-time detection of the hot cover temperature and precise local heating, ensuring the uniformity of the hot cover temperature and eliminating local condensation problems. At the same time, an edge sealing frame with a fitting movable part is set at the lower end of the bottom shell of the hot cover. The fitting movable part can adaptively deform according to the edge structure of different PCR tube sizes to achieve a full-range tight seal between the hot cover and the PCR tube, reduce heat loss, and strengthen the core functions of preventing evaporation and condensation. Attached Figure Description
[0015] To more clearly illustrate the technical solutions in this invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only for this invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0016] Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2This is a top view of the heat cover fixing bracket in this invention. Figure 3 This is a side view of the structure of the heat cover bottom shell and the heat cover fixing plate in this invention; Figure 4 This is an exploded view of the structure of the heat-sealed bottom shell and the connecting plate in this invention; Figure 5 This is an exploded view of the voltage regulating module in this invention; Figure 6 This is a partial structural diagram of the voltage regulation module in this invention; Figure 7 This is an exploded view of a portion of the structure of the buffer bolt, the annular detection seat, and the hot cover bottom shell in this invention. Figure 8 This is a cross-sectional view of the connection structure between the buffer bolt and the fitting rubber sleeve in this invention; Figure 9 This is an exploded view of a portion of the temperature sensing adjustment module on the bottom shell of the heat cover in this invention; Figure 10 This is a partial structural cross-sectional view of the temperature sensing adjustment module on the bottom shell of the heat cover in this invention.
[0017] In the diagram: 1. Heated cover bottom shell; 2. Heated cover fixing plate; 3. Heated cover fixing bracket; 4. Flat pressure assembly; 5. Vertical motor; 6. Vertical rack; 7. Horizontal gear; 8. Support cylinder; 9. Linkage displacement assembly; 10. Slider; 11. Guide rod frame; 12. Horizontal motor; 13. Synchronous pulley shaft; 14. Belt body; 15. Belt pressure plate; 16. Pressure regulating module; 17. Connecting plate; 18. Buffer bolt; 19. Support spring; 20. Adhesive rubber sleeve; 21. Extrusion ring; 22. Annular detection seat; 23. Point detection end; 24. Temperature sensing adjustment module; 25. Edge sealing frame; 26. Adhesive moving part; 27. Temperature measuring chamber; 28. Detection probe; 29. Temperature regulating resistor. Detailed Implementation
[0018] The specific embodiments of the present invention will now be described in detail with reference to the accompanying drawings.
[0019] Please see Figure 1-10 The present invention provides a technical solution: A PCR instrument hot cover device is disclosed. In existing devices, the hot cover bottom shell 1 is used to press against the PCR tubes. The upper end of the hot cover bottom shell 1 is connected to the hot cover fixing plate 2 and the hot cover fixing frame 3. The hot cover fixing frame 3 is used to install on the upper side of the PCR instrument. The hot cover bottom shell 1, the hot cover fixing plate 2, and the hot cover fixing frame 3 serve as the basic support structure. A flat pressing assembly 4 is assembled between the hot cover bottom shell 1 and the hot cover fixing plate 2. A vertical motor 5 in the flat pressing assembly 4 serves as the driving device. The vertical motor 5 is vertically connected to the hot cover fixing plate 2. The power output end of the vertical motor 5 is fixedly connected to a horizontal gear 7. A vertical rack 6 is used on one side of the horizontal gear 7. The lower end of the vertical rack 6 is fixedly connected to the hot cover bottom shell 1. At the same time, the vertical rack 6 meshes with the horizontal gear 7. By applying the forward and reverse rotation of the motor, the vertical motor 5 drives the horizontal gear 7 to rotate forward and reverse. The rotating horizontal gear 7 meshes with the vertical rack 6, thereby driving the vertical rack 6 to move forward and backward. Driven in the up-and-down direction, the hot cover bottom shell 1 can move up and down, locking and sealing different sizes of PCR instruments below. Next, to ensure the stability of the vertical rack 6's up-and-down movement, multiple supporting cylinders 8 can be set on the top of the hot cover bottom shell 1. The multiple supporting cylinders 8 and the top of the vertical plug 6 are set with the same plate, which supports the top of the vertical rack 6. Furthermore, the upper end of the vertical rack 6 can pass through the plate. According to the size of the vertical rack 6, a slot is opened on the hot cover fixing plate 2 for the vertical rack 6 to move through. When the vertical rack 6 drives the hot cover bottom shell 1 upward to the hot cover fixing plate 2, the vertical rack 6 can pass through the slot and be contained in the slot, providing stable height adjustment for the hot cover bottom shell 1. The flat pressure component 4 can flexibly drive the vertical rack 6 to move up and down according to the height of different sizes of PCR tubes, driving the hot cover moving plate 2 to accurately press down and seal PCR tubes of different sizes and heights.Simultaneously, linkage displacement components 9 for driving horizontal movement can be set at both ends of the hot cover fixing plate 2. A pair of guide rod frames 11 in the linkage displacement components 9 are fixedly mounted in parallel inside the hot cover fixing frame 3. Compared with the single guide rod mechanism on the market, this can reduce jamming and uneven movement. The horizontal motor 12 is assembled on the corresponding position on the hot cover fixing frame 3. Slider 10s are fixedly installed on both sides of the hot cover fixing plate 2. The slider 10 is slidably sleeved on the guide rod frame 11. Rollers that fit against the guide rod frame 11 are rotatably installed on the inner side of the slider 10 to increase the smoothness of sliding of the slider 10 on the guide rod frame 11. Then, two pairs of synchronous pulley shafts 13 aligned and parallel to the guide rod frame 11 are installed on the hot cover fixing frame 3. The end of one of the synchronous pulley shafts 13 is connected to the horizontal motor 12. The same belt body 14 is sleeved on the outside of each pair of synchronous pulley shafts 13, and the belt body 14 is fixedly connected to the slider 10 to facilitate the horizontal movement of the slider 10 and the hot cover bottom shell 1. A stable drive is provided, and finally, a belt pressure plate 15 is installed on the hot cover fixing frame 3 to limit the belt body 14. When it is necessary to drive the hot cover to move horizontally, the horizontal motor 12 is started. The horizontal motor 12 drives the connected synchronous pulley shaft 13 to rotate. The synchronous pulley shaft 13 drives the externally sleeved belt body 14 to drive. The belt body 14 drives the fixed slider 10 to slide along the guide rod frame 11. The slider 10 drives the hot cover fixing plate 2 and the hot cover bottom shell 1 connected above to move horizontally. The ball bearings on the inner side of the slider 10 roll in contact with the guide rod frame 11 to reduce sliding friction and accurately move the hot cover bottom shell 1 above the PCR instrument. In some embodiments, a distance detector, such as a position sensor or an infrared sensor, can also be set on one side of the hot cover bottom shell 1. The distance detector is connected to the horizontal motor 12. By using the controller on the hot cover device, the distance between the hot cover bottom shell 1 and the hot cover fixing frame 3 can be measured, and the movement status of the hot cover bottom shell 1 can be detected and controlled in real time.
[0020] When using the heated lid device, the coordinated design of the pressure-adjusting component 4 and the linkage displacement component 9 enables automated adjustment of the heated lid in both horizontal and vertical directions, avoiding operational errors caused by insufficient operator experience. Simultaneously, the ball bearings inside the slider 10 effectively improve the smoothness of the heated lid's horizontal movement, reducing jamming during movement. The pressure-adjusting component 4 can flexibly drive the vertical rack 6 according to the height of different PCR tube sizes, adjusting the height of the heated lid's bottom shell 1 to achieve precise downward sealing of PCR tubes of different sizes and heights. The automated control of the entire adjustment process ensures precise closing position and downward pressure of the heated lid, guaranteeing a tight seal between the heated lid's bottom shell 1 and the PCR tube. Furthermore, the coordinated design of the dual synchronous pulley shaft 13 and the belt body 14 of the linkage displacement component 9 makes the horizontal movement of the heated lid more stable, achieving precise alignment between the heated lid and the PCR instrument, further improving the operational accuracy of PCR experiments.
[0021] Next, to ensure the uniformity of the downward sealing of the pressure-equalizing assembly 4, a connecting plate 17 can be clamped at the lower end of the pressure-equalizing assembly 4. Multiple pressure-regulating modules 16 are installed through the connecting plate 17. The lower end of the pressure-regulating module 16 is vertically fixedly connected to the bottom shell 1 of the hot cover. The pressure-regulating module 16 can control the vertical motor 5 to automatically lock the PCR instrument, ensuring the stability of the hot cover movement, detecting the downward pressure, and accurately adjusting the downward pressure value. When the pressure-equalizing assembly 4 drives the bottom shell 1 of the hot cover to move downward and complete the downward pressure on the PCR tube, the bottom shell 1 of the hot cover is subjected to the reaction force of the PCR tube. This reaction force is transmitted to the pressure-regulating module 16. The pressure-regulating module 16 adaptively adjusts according to the actual downward pressure force, changing the downward pressure of the bottom shell 1 on the PCR tube, realizing the pressure regulation and sealing of the hot cover on the PCR instrument, reducing the occurrence of intermittent condensation problems. Moreover, the uniform distribution of multiple pressure-regulating modules 16 ensures that the pressure regulation intensity is evenly distributed below the bottom shell 1 of the hot cover, ensuring the uniformity of the downward sealing and ensuring the stability of the PCR experiment.
[0022] In some embodiments, the pressure regulating module 16 can be fitted with a buffer bolt 18 through a connecting plate 17. A support spring 19 is sleeved on the outside of the buffer bolt 18, and the support spring 19 abuts against the connecting plate 17 and the hot cover bottom shell 1. Then, a rubber sleeve 20 is sleeved on both the inner and outer sides of the support spring 19. The outer rubber sleeve 20 is completely sleeved with the support spring 19. The outer side of the rubber sleeve 20 can have a through hole to allow the support spring 19 to deform in length. The inner rubber sleeve 20 can be set with a wave-shaped structure. When the support spring 19 is compressed and deformed, the rubber sleeves 20 on both sides deform and fit against the surface of the support spring 19, which can smoothly consume the force on the spring. Then, a compression ring 21 is installed at the lower end of the support spring 19. An annular detection seat 22 for the buffer bolt 18 to pass through is provided on the hot cover bottom shell 1. The top of the annular detection seat 22 uses several point-shaped detection ends 23 pressure detection ends. Using a pressure sensor with a point-like detection end 23, the pressure on the spring is accurately and safely detected with greater pressure and the use of an arc-shaped surface, allowing for precise control of the downward pressure of the hot cap. Next, the compression ring 21 is fitted and fixed to the outside of the annular detection seat 22 to seal the gap between the annular detection seats 22 and achieve structural connection. Finally, the lower end of the buffer bolt 18 is threaded to the bottom shell 1 of the hot cap. By rotating the buffer bolt 18 toward the bottom shell 1 of the hot cap, the elastic pressure of the support spring 19 can be adjusted, realizing the pressure adjustability of the pressure regulating module 16. The pressure regulating module 16, together with the vertical motor 5, adjusts the height of the bottom shell 1 of the hot cap, realizing adaptive adjustment of the downward pressure, keeping the downward pressure of the hot cap within a suitable range, minimizing the deformation of the PCR tube. At the same time, the cooperation between the annular detection seat 22 and the compression ring 21 limits the pressure adjustment process, improving the stability of the pressure regulating seal.
[0023] Furthermore, several temperature-sensing adjustment modules 24 can be installed on the lower surface of the bottom shell 1 of the hot cover to monitor the temperature of each area of the hot cover in real time and supplement the heating at the temperature difference points to ensure the uniformity of the working heat of the hot cover. The temperature-sensing adjustment module 24 first opens a temperature measuring cavity 27 on the bottom shell 1 of the hot cover, and installs the detection probe 28 in the middle of the temperature measuring cavity 27. The detection probe 28 is located on the lower surface of the bottom shell 1 of the hot cover that contacts the PCR tube, ensuring that the top of the detection probe 28 is flush with the surface of the bottom shell 1 of the hot cover. The detection probe 28 uses a temperature sensor and is connected to the PCR instrument, which facilitates the transmission of the detected data to the PCR instrument. It can monitor the stability of the hot cover at different temperatures, set the temperature difference control value in the controller, and provide data support for supplementing the heating of the hot cover by comparing the detection data with the temperature difference control value. It can also control the temperature adjustment resistor 29 that requires temperature control without affecting the sealing and locking of the PCR instrument. Meanwhile, an arc-shaped temperature-regulating resistor 29 can be fitted inside the temperature-measuring chamber 27. The temperature-regulating resistor 29 is used in conjunction with the detection probe 28 to facilitate the controller to control the power supply and quickly replenish the heat at the temperature deviation position, so that the temperature of the bottom shell 1 of the hot cover is always uniform and stable. This effectively avoids the generation of condensate caused by local temperature deviation, further improves the anti-condensation performance of the hot cover, ensures the temperature cycling accuracy of the experimental PCR reaction, and improves the repeatability and accuracy of the PCR experiment.
[0024] Furthermore, in some embodiments, an edge sealing frame 25 can be installed at the lower end of the hot-cover bottom shell 1. Several engaging movable parts 26 are arranged on the surface of the edge sealing frame 25, with the lower ends of the engaging movable parts 26 extending to the middle of the edge sealing frame 25. When the hot-cover bottom shell 1 moves downwards to complete the downward sealing of the PCR tube, the edge sealing frame 25 first contacts the edge of the PCR tube. As the hot-cover bottom shell 1 continues to press down, the edge sealing frame 25 is subjected to compressive force. The engaging movable parts 26 on its surface adaptively deform according to the shape and specifications of the PCR tube edge, allowing the edge sealing frame 25 to tightly fit the edges of PCR tubes of different specifications. This increases the adaptive strength of the hot cover, completing the sealing process of the hot cover for PCR instruments of different specifications, effectively reducing heat loss, making the high-temperature environment of the hot cover more stable, and making the temperature cycle of the PCR reaction more precise.
[0025] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. The present invention is not limited to the above embodiments; the embodiments and descriptions in the specification are merely illustrative of the principles of the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this invention is defined by the appended claims and their equivalents.
Claims
1. A PCR instrument heating cover device, comprising a heating cover bottom shell (1), a heating cover fixing plate (2), and a heating cover fixing frame (3), characterized in that: A pressure assembly (4) for adjusting the height of the heat cover bottom shell (1) is provided between the heat cover fixing plate (2). The pressure assembly (4) includes a vertical motor (5) that is vertically connected to the heat cover fixing plate (2). A horizontal gear (7) is provided at the power output end of the vertical motor (5). A vertical rack (6) that is fixed to the heat cover bottom shell (1) is meshed on one side of the horizontal gear (7). A plurality of support cylinders (8) supporting the vertical rack (6) are provided on the top of the heat cover bottom shell (1) for pressing and sealing PCR tubes of different specifications. Both ends of the hot cover fixing plate (2) are provided with linkage displacement components (9) for driving horizontal movement. The linkage displacement components (9) include a pair of guide rods (11) fixed in parallel in the hot cover fixing frame (3). The sides of the hot cover fixing plate (2) are fixed with sliders (10) that slide on the guide rods (11) for precise alignment of the hot cover with the PCR instrument.
2. The PCR instrument heating cover device as described in claim 1, characterized in that, The horizontal gear (7) is used to rotate via the vertical motor (5). The top of the multiple supporting cylinders (8) is provided with the same plate. The vertical rack (6) is movably connected to the heat cover fixing plate (2). The vertical rack (6) adjusts the height of the heat cover bottom shell (1) via the horizontal gear (7) for locking and sealing the PCR instrument.
3. The PCR instrument heating cover device as described in claim 1, characterized in that, The inner side of the slider (10) is rotatably provided with ball bearings that fit against the guide rod frame (11) to improve the smoothness of the horizontal movement of the heat cover fixing plate (2).
4. The PCR instrument heating cover device as described in claim 3, characterized in that, The linkage displacement assembly (9) also includes a pair of horizontal motors (12) fixedly mounted on the hot cover fixing frame (3). The hot cover fixing frame (3) is provided with two pairs of synchronous pulley shafts (13) aligned and parallel to the guide rod frame (11). The end of each synchronous pulley shaft (13) is connected to a horizontal motor (12). The same belt body (14) is sleeved on the outside of each pair of synchronous pulley shafts (13). The belt body (14) is fixedly connected to the slider (10). The hot cover fixing frame (3) is provided with a belt pressure plate (15) that limits the belt body (14) for stable driving of the horizontal movement of the hot cover bottom shell (1).
5. The PCR instrument heating cover device as described in claim 1, characterized in that, The lower end of the pressure-regulating component (4) is clamped with a connecting plate (17), and multiple pressure-regulating modules (16) are provided through the connecting plate (17). The lower end of the pressure-regulating module (16) is vertically connected to the bottom shell of the hot cover (1) for pressure regulation and sealing of the PCR instrument by the hot cover.
6. The PCR instrument heating cover device as described in claim 5, characterized in that, The pressure regulating module (16) includes a buffer bolt (18) that passes through the connecting plate (17). A support spring (19) is sleeved on the outside of the buffer bolt (18) and abuts against the connecting plate (17) and the hot cover bottom shell (1). Both the inner and outer sides of the support spring (19) are fitted with rubber sleeves (20). A compression ring (21) is provided at the lower end of the support spring (19). An annular detection seat (22) is provided on the hot cover bottom shell (1) for the buffer bolt (18) to pass through. The compression ring (21) is sleeved on the outside of the annular detection seat (22). Several point-like detection ends (23) are provided on the top of the annular detection seat (22). The lower end of the buffer bolt (18) is threaded to the hot cover bottom shell (1) for stable pressing of the hot cover against the PCR instrument.
7. The PCR instrument heating cover device as described in claim 1, characterized in that, The lower surface of the heat cover bottom shell (1) is provided with several temperature sensing adjustment modules (24) for the heat cover to detect the temperature of the PCR instrument and provide local heating.
8. The PCR instrument heating cover device as described in claim 7, characterized in that, The temperature sensing adjustment module (24) includes a temperature measuring chamber (27) opened on the bottom shell of the hot cover (1). A detection probe (28) is provided in the middle of the temperature measuring chamber (27). The detection probe (28) is located on the lower surface of the bottom shell of the hot cover (1) in contact with the PCR tube. A temperature regulating resistor (29) is sleeved inside the temperature measuring chamber (27). The temperature regulating resistor (29) has an arc-shaped structure.
9. The PCR instrument heating cover device as described in claim 8, characterized in that, The lower end of the heat cover bottom shell (1) is provided with an edge sealing frame (25). The surface of the edge sealing frame (25) is provided with a plurality of fitting movable parts (26). The lower end of the fitting movable parts (26) extends to the middle of the edge sealing frame (25) for sealing the heat cover with PCR instruments of different specifications.