A method for optimizing neural electrical stimulation parameters and a neural stimulation system based on a modified intensity-time model.

CN122321342APending Publication Date: 2026-07-03SUZHOU RUIYI XULIAN MEDICAL TECHNOLOGY CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SUZHOU RUIYI XULIAN MEDICAL TECHNOLOGY CO LTD
Filing Date
2026-06-05
Publication Date
2026-07-03

AI Technical Summary

Technical Problem

Existing neurostimulators lack individualized adaptive optimization capabilities, which means they cannot automatically adjust parameters when there are changes or micro-displacements at the electrode-tissue interface. This can easily lead to understimulation or overstimulation, affecting therapeutic efficacy and patient comfort.

Method used

A neural electrical stimulation parameter optimization method based on a modified intensity-time model is adopted. By applying electrical stimulation with multiple preset pulse widths, the minimum domain stimulation intensity is collected, and individualized parameters Irh, Qth, and c are fitted. The stimulation current intensity and pulse width are adjusted in real time, and the k value is optimized by combining conduction velocity and fiber type to achieve closed-loop adaptive control.

Benefits of technology

It improves the fitting accuracy and calculation ease of stimulation parameters, reduces energy consumption, avoids understimulation or overstimulation, enhances therapeutic efficacy and patient comfort, and extends the battery life of implantable devices.

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Abstract

This invention discloses a method and system for optimizing neural electrical stimulation parameters based on a modified intensity-time model. The method includes: performing prior tests on the target nerve, including: applying electrical stimulation with multiple preset pulse widths and acquiring the pulse widths of each pulse. t i Minimum domain stimulus intensity I i ; Utilizing multiple pairs ( t i , I i The data was fitted to the following modified intensity-time model to obtain individualized parameters. I rh , Q th , c :, I rh The base intensity is defined as the minimum stimulation current intensity required to induce nerve excitation when the pulse width approaches infinity. Q th The threshold charge constant is related to the membrane capacitance characteristics. c To correct the time constant, a threshold stimulation current intensity between 1.85 and 2.15 times the base intensity was used as the optimized value, and the corresponding required pulse width for a single electrical stimulation was calculated as the optimized value for the pulse width.
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