Oral products and methods for their manufacture

Abstract

The application discloses a kind of oral products and its preparation method, it is related to oral product field.Oral product includes oral composition, the oral composition includes active agent, filler, flavor and water, the filler includes corn silk;The content of corn silk in the oral composition is not less than 10 mass parts.The application uses corn silk as filler, corn silk has the characteristics of high water absorption, can be rapidly absorbed in oral cavity Wet expansion, form soft fiber layer, bring "natural, cotton" touch, can significantly improve oral comfort, improve user experience, improve the problem of dry mouth caused by using microcrystalline cellulose as filler alone;It can effectively buffer the friction between oral product and gum, reduce gum abrasion;It can also improve the release rate and release amount of active ingredients, so that active ingredient nicotine is quickly dissolved in a short time, which is beneficial to improve satisfaction and improve the use experience of product.

Description

Technical Field

[0001] This application relates to the field of oral products, and more particularly to an oral product and its preparation method. Background Technology

[0002] Currently, microcrystalline cellulose is mainly used as a filler in oral products. However, microcrystalline cellulose has a dry texture and can easily cause gum abrasion when used in the oral cavity.

[0003] To alleviate the above problems, existing technologies often involve spraying a layer of lubricating material onto the outer surface of the permeable bag. However, the lubricating material does not bond firmly to the permeable bag and is easily washed away by saliva in the mouth; moreover, the lubricating material may affect the release of active ingredients; in addition, the spraying process increases the complexity of the process and production costs. Summary of the Invention

[0004] The purpose of this application is to provide an oral product and a method for preparing the same, in order to solve the above-mentioned problems.

[0005] To achieve the above objectives, this application adopts the following technical solution: A mouth-sucking article comprising a mouth-sucking composition, the mouth-sucking composition comprising an active agent, a filler, a flavoring agent, and water, the filler comprising corn silk; The corn silk content in the oral composition is not less than 10 parts by weight.

[0006] In some embodiments, the water content in the oral composition is 3 to 50 parts by weight; and / or, The corn silk refers to corn silk particles, and at least 90% of the corn silk particles have a particle size of 30 mesh to 150 mesh.

[0007] In some embodiments, the filler further includes microcrystalline cellulose; and / or, The flavoring agent includes at least one of a cooling agent, a sweetener, and an edible flavoring; and / or, The oral composition further includes a pH adjuster; and / or, The oral article also includes a permeable bag, into which the oral composition is filled.

[0008] In some embodiments, the oral composition comprises 1-20 parts by weight of an active agent, 0-65 parts by weight of microcrystalline cellulose, 10-80 parts by weight of corn silk, 0-2 parts by weight of a cooling agent, 0.1-20 parts by weight of a sweetener, 0.1-20 parts by weight of an edible flavoring, 3-50 parts by weight of water, and 0-1 parts by weight of a pH adjuster.

[0009] In some embodiments, the active agent includes at least one of nicotine and nicotine derivatives, wherein the nicotine derivatives include at least one of substituted nicotine, unsubstituted nicotine salts, and substituted nicotine salts. And / or, the sweetener comprises at least one of xylitol, sorbitol, mannitol, iodine, lactitol, maltitol, isomaltitol, hydrogenated starch hydrolysate, erythritol, maltotriol, aspartame, acesulfame potassium, sodium saccharin, sucralose, neotame, cyclamate, alitane, steviol glycosides, arabinitol, and monk fruit sweetener; And / or, the cooling agent includes at least one of WS-23, WS-3, and WS-5.

[0010] In some embodiments, the corn silk content in the oral composition is 15-45 parts by weight.

[0011] This application also provides a method for preparing an oral article as described above, comprising: A mouth-sucking composition is obtained, the mouth-sucking composition comprising an active agent, a filler, a flavoring agent, and water; Granulation was performed using the oral composition to obtain oral granules; The oral granules are placed into a permeable bag to obtain an oral product.

[0012] In some embodiments, obtaining the oral composition includes obtaining corn silk; The process of obtaining corn silk includes the following steps: drying the corn silk raw material at a temperature of 50-70℃ so that the moisture content of the processed corn silk is less than or equal to 5%, crushing, screening and obtaining corn silk particles of the target particle size.

[0013] In some embodiments, the filler further includes microcrystalline cellulose; The granulation using the oral composition includes: Microcrystalline cellulose and corn silk granules were mixed under stirring conditions to obtain a mixed powder. The active agent, flavoring agent and water are mixed to prepare a mixture; The mixed powder is mixed with the mixed liquid to prepare the oral granules.

[0014] In some embodiments, the method for preparing the mixture further includes adding a pH adjuster.

[0015] In some embodiments, mixing the microcrystalline cellulose and the corn silk granules under stirring conditions includes: placing the microcrystalline cellulose and the corn silk granules in a wet granulation pan and stirring to mix them evenly, wherein the stirring speed is 100~200 rpm and the stirring time is 1~5 min; And / or, the mixing of the mixed powder with the mixed liquid includes: slowly pouring the mixed liquid into the mixed powder that has been placed in a wet granulation pot, stirring and granulating, wherein the stirring rate is 100~200 rpm, the cutting speed is 500~2000 rpm, and the stirring and granulation time is 1~10 min; And / or, the moisture content of the oral granules prepared by mixing the mixed powder with the mixed liquid is controlled at 10-25%; And / or, after the oral granules are placed into a permeable bag, the method further includes: humidifying the permeable bag to bring the moisture content of the oral granules to 35-50%.

[0016] In some embodiments, the moisture content of the oral granules is 35%-45%.

[0017] Compared with the prior art, the beneficial effects of this application include: This application uses corn silk as a filler. Corn silk has the characteristic of high water absorption, which can quickly absorb moisture and expand in the oral cavity to form a soft fiber layer, bringing a "natural, cotton-like" touch. It can significantly improve oral comfort, enhance user experience, and improve the dry mouth sensation caused by using microcrystalline cellulose as a filler alone. At the same time, it effectively buffers the friction between oral products and the gums, reducing gum wear.

[0018] The corn silk in this application is not prone to clumping under high moisture conditions, and the corn silk granules have good dispersibility, facilitating wet granulation and exhibiting excellent processing performance, which is beneficial for the stable production of oral products. More importantly, in the oral products of this application, when the corn silk content is not less than 10 parts by weight, the release rate and amount of the active ingredient nicotine can be significantly increased, enabling the active ingredient nicotine to be released rapidly and more completely in a short time, which helps to enhance satisfaction and improve the user experience.

[0019] The oral product of this application does not require additional coating of lubricating material on the outer surface of the permeable bag, thus avoiding problems such as the lubricating layer being easily washed away by saliva and failing, affecting the release of active substances, while simplifying the production process and reducing production costs. Detailed Implementation

[0020] As used in this article: "Prepared from" is synonymous with "comprising". The terms "comprising", "including", "having", "containing", or any other variations thereof as used herein are intended to cover non-exclusive inclusion. For example, a composition, step, method, article, or apparatus that includes the listed elements is not necessarily limited to those elements, but may include other elements not expressly listed or elements inherent to such composition, step, method, article, or apparatus.

[0021] The conjunction "composed of..." excludes any unspecified elements, steps, or components. If used in a claim, this phrase makes the claim closed, excluding materials other than those described, except for associated conventional impurities. When the phrase "composed of..." appears in a clause of the body of a claim rather than immediately following it, it limits only the elements described in that clause; other elements are not excluded from the claim as a whole.

[0022] When a quantity, concentration, or other value or parameter is expressed as a range, a preferred range, or a range defined by a series of upper and lower preferred values, this should be understood as specifically disclosing all ranges formed by any pair of any upper or preferred value with any lower or preferred value, regardless of whether the range is disclosed individually. For example, when the range “1–5” is disclosed, the described range should be interpreted as including ranges “1–4”, “1–3”, “1–2”, “1–2 and 4–5”, “1–3 and 5”, etc. When numerical ranges are described herein, unless otherwise stated, the range is intended to include its endpoints and all integers and fractions within that range.

[0023] In these embodiments, unless otherwise specified, the portions and percentages are all by weight.

[0024] "Parts by mass" refers to the basic unit of measurement that expresses the mass ratio of multiple components. One part can represent any unit mass, such as 1g or 2.689g. If we say that component A has "a" parts by mass and component B has "b" parts by mass, it means the ratio of the mass of component A to the mass of component B is a:b. Alternatively, it can mean that the mass of component A is aK and the mass of component B is bK (where K is any number representing a multiplier). It is important to understand that, unlike parts by mass, the sum of the mass parts of all components is not limited to 100 parts.

[0025] "And / or" is used to indicate that one or both of the described situations may occur, for example, A and / or B includes (A and B) and (A or B).

[0026] A mouth-sucking product includes a mouth-sucking composition comprising an active agent, a filler, a flavoring agent, and water, wherein the filler comprises corn silk; the corn silk content in the mouth-sucking composition is not less than 10 parts by weight.

[0027] Compared to traditional filler microcrystalline cellulose, corn silk has better water absorption and is softer. Using it as a filler can bring a more "natural, cotton-like" feel, reduce gum wear, protect the gums, significantly improve oral comfort, and enhance the user experience.

[0028] In some embodiments, the oral composition contains 3 to 50 parts by weight of water.

[0029] For example, the water content in the oral composition is 3 parts by weight, 5 parts by weight, 8 parts by weight, 10 parts by weight, 13 parts by weight, 15 parts by weight, 18 parts by weight, 20 parts by weight, 23 parts by weight, 25 parts by weight, 28 parts by weight, 30 parts by weight, 33 parts by weight, 35 parts by weight, 38 parts by weight, 40 parts by weight, 43 parts by weight, 45 parts by weight, 48 parts by weight, 50 parts by weight, or any value between 3 and 50 parts by weight.

[0030] In some embodiments, the corn silk is in the form of corn silk granules, with at least 90% of the granules having a particle size of 30 to 150 mesh. If the corn silk granules are too small, they are prone to leaking out through the pores of the permeable bag; if the granules are too large, they will cause a grainy or foreign body sensation when held in the mouth, affecting user comfort. When the particle size of the corn silk granules is within the above range, user comfort can be improved while ensuring the integrity of the oral product.

[0031] For example, no less than 90% of the corn silk particles have a particle size of 30 mesh, 40 mesh, 50 mesh, 60 mesh, 70 mesh, 80 mesh, 90 mesh, 100 mesh, 110 mesh, 120 mesh, 130 mesh, 140 mesh, 150 mesh, or any value between 30 mesh and 150 mesh.

[0032] The particle size of corn silk can be measured by laser diffraction.

[0033] In some embodiments, the filler also includes microcrystalline cellulose.

[0034] For example, the types of microcrystalline cellulose include, but are not limited to, microcrystalline cellulose 101, 102, 112, and 200.

[0035] In some embodiments, the flavoring agent includes at least one of a cooling agent, a sweetener, and an edible flavoring.

[0036] In some embodiments, the flavoring includes peppermint flavoring.

[0037] In some embodiments, the oral composition further includes a pH adjuster.

[0038] In some embodiments, the pH adjuster includes sodium bicarbonate.

[0039] In some embodiments, the oral article further includes a permeable pouch, into which the oral composition is filled.

[0040] In some embodiments, the oral composition comprises 1-20 parts by weight of an active agent, 0-65 parts by weight of microcrystalline cellulose, 10-80 parts by weight of corn silk, 0-2 parts by weight of a cooling agent, 0.1-20 parts by weight of a sweetener, 0.1-20 parts by weight of an edible flavoring, 3-50 parts by weight of water, and 0-1 parts by weight of a pH adjuster.

[0041] By controlling the corn silk content within the aforementioned range, this application can fully utilize the characteristics of corn silk to improve the taste, while also avoiding the problem of poor flowability of the granules in the mouth caused by excessive corn silk addition, thus ensuring the uniformity of the bagging quality.

[0042] The bulk density of corn silk is lower than that of microcrystalline cellulose. When the content of corn silk and microcrystalline cellulose in the oral composition is within the above range, it is beneficial to the rapid release of nicotine, improves the user experience, and also makes the bag shape of the oral product more aesthetically pleasing.

[0043] For example, the content of the active agent in the oral composition is 1 part by weight, 5 parts by weight, 10 parts by weight, 15 parts by weight, 20 parts by weight, or any value between 1 and 20 parts by weight; the content of microcrystalline cellulose in the oral composition is 0, 5 parts by weight, 10 parts by weight, 15 parts by weight, 20 parts by weight, 25 parts by weight, 30 parts by weight, 35 parts by weight, 40 parts by weight, 45 parts by weight, 50 parts by weight, 55 parts by weight, 60 parts by weight, 65 parts by weight, or 0-65 parts by weight. Any value between parts by weight; the content of corn silk in the oral composition is 10 parts by weight, 15 parts by weight, 20 parts by weight, 25 parts by weight, 30 parts by weight, 35 parts by weight, 40 parts by weight, 45 parts by weight, 50 parts by weight, 55 parts by weight, 60 parts by weight, 65 parts by weight, 70 parts by weight, 75 parts by weight, 80 parts by weight, or any value between 10 and 80 parts by weight; the content of cooling agent in the oral composition is 0, 0.2 parts by weight, 0.5 parts by weight, 0. The content of sweetener in the oral composition is 0.1, 5, 10, 15, 20 parts by weight, or any value between 0.1 and 20 parts by weight; the content of edible flavoring in the oral composition is 0.1, 5, 10, 15, 20 parts by weight, or any value between 0.1 and 20 parts by weight. Any value between 20 parts by mass; the water content in the oral composition is any value between 3, 5, 10, 15, 20, 25, 30, 35, 40, 45, 50 parts by mass or between 3 and 50 parts by mass; the pH adjuster content in the oral composition is any value between 0, 0.2, 0.5, 0.7, 1 part by mass or between 0 and 1 part by mass.

[0044] In some embodiments, the active agent includes at least one of nicotine and nicotine derivatives.

[0045] Nicotine derivatives include at least one of substituted nicotine, unsubstituted nicotine salts, and substituted nicotine salts. The substituents include, but are not limited to, alkyl groups, such as methyl groups.

[0046] For example, nicotine containing substituents includes 6-methylnicotine.

[0047] For example, unsubstituted nicotine salts include at least one of nicotine tartrate, nicotine resin salt, nicotine benzoate, nicotine malate, nicotine lactate, nicotine valerate, nicotine salicylate, nicotine hydrochloride, nicotine sulfate, nicotine citrate, nicotine oxalate, and nicotine malonate.

[0048] In some embodiments, the sweetener includes at least one of xylitol, sorbitol, mannitol, iodine, lactitol, maltitol, isomaltitol, hydrogenated starch hydrolysate, erythritol, maltotriol, aspartame, acesulfame potassium, sodium saccharin, sucralose, neotame, cyclamate, alitane, steviol glycosides, arabinitol, and monk fruit sweetener.

[0049] In some embodiments, the cooling agent includes at least one of WS-23, WS-3, and WS-5.

[0050] In some embodiments, the corn silk content in the oral composition is 15-45 parts by weight.

[0051] This application also provides a method for preparing a mouth-sucking product as described above, comprising: obtaining a mouth-sucking composition, the mouth-sucking composition comprising an active agent, a filler, a flavoring agent, and water; granulating the mouth-sucking composition to obtain mouth-sucking granules; and filling the mouth-sucking granules into a permeable bag to obtain a mouth-sucking product.

[0052] In some embodiments, obtaining the oral composition includes obtaining corn silk; obtaining corn silk includes the following steps: drying the corn silk raw material at a temperature of 50-70°C (e.g., 50°C, 55°C, 60°C, 65°C, 70°C or any value between 50-70°C) to make the moisture content of the treated corn silk less than or equal to 5%, crushing, screening and obtaining corn silk particles of the target particle size.

[0053] This application dries the corn silk raw material at a temperature of 50-70℃, which helps to quickly remove moisture from the corn silk raw material and facilitates subsequent pulverization.

[0054] In some embodiments, the filler also includes microcrystalline cellulose.

[0055] Granulation using a mouth-held composition includes: mixing microcrystalline cellulose with corn silk granules under stirring conditions to obtain a mixed powder; mixing an activator, a flavoring agent, and water to prepare a mixed solution; and mixing the mixed powder with the mixed solution to prepare mouth-held granules.

[0056] In some embodiments, the preparation method further includes adding a pH adjuster when preparing the mixture.

[0057] In some embodiments, mixing microcrystalline cellulose and corn silk granules under stirring conditions includes: placing microcrystalline cellulose and corn silk granules in a wet granulation pan and stirring to mix them evenly, wherein the stirring rate is 100~200 rpm and the stirring time is 1~5 min.

[0058] For example, the stirring rate of microcrystalline cellulose and corn silk is 100 rpm, 120 rpm, 150 rpm, 170 rpm, 200 rpm or any value between 100 and 200 rpm; the stirring time of microcrystalline cellulose and corn silk is 1 min, 2 min, 3 min, 4 min, 5 min or any value between 1 and 5 min.

[0059] In some embodiments, mixing the powder and the liquid mixture includes: slowly pouring the liquid mixture into the powder mixture already placed in a wet granulation pan, stirring and granulating, wherein the stirring rate is 100~200 rpm, the cutter speed is 500~2000 rpm, and the stirring and granulation time is 1~10 min.

[0060] For example, in the granulation step, the stirring rate is any value between 100 rpm, 120 rpm, 150 rpm, 170 rpm, 200 rpm, or 100~200 rpm; the cutting speed is any value between 500 rpm, 700 rpm, 1000 rpm, 1200 rpm, 1500 rpm, 1700 rpm, 2000 rpm, or 500~2000 rpm; and the stirring and granulation time is any value between 1 min, 3 min, 5 min, 7 min, 10 min, or 1~10 min.

[0061] In some embodiments, the powder is mixed with the liquid to prepare oral granules with a moisture content controlled at 10-25% (e.g., any value between 10%, 15%, 20%, 25% or 10-25%).

[0062] In some embodiments, after the oral granules are placed into a permeable bag, the method further includes humidifying the permeable bag to bring the moisture content of the oral granules to 35-50% (e.g., any value between 35%, 40%, 45%, 50%, or 35-50%).

[0063] In some embodiments, the moisture content of the oral granules is 35%-45%.

[0064] The inventors discovered that by controlling the moisture content of the oral granules within the aforementioned range, a rapid and high-intensity release of aroma, active ingredients, and sweetness can be achieved.

[0065] The implementation schemes of this application will be described in detail below with reference to specific embodiments. However, those skilled in the art will understand that the following embodiments are only for illustrating this application and should not be regarded as limiting the scope of this application. Unless otherwise specified in the embodiments, conventional conditions or conditions recommended by the manufacturer shall apply. Reagents or instruments used without specified manufacturers are all conventional products that can be purchased commercially.

[0066] Example 1 Example 1 provides a mouth-sucking product comprising a mouth-sucking composition as shown in Table 1. The mouth-sucking composition comprises 60.60 parts by weight of microcrystalline cellulose 102, 10 parts by weight of corn silk granules, 2.4 parts by weight of nicotine, 15 parts by weight of purified water, 0.5 parts by weight of WS-23, 0.5 parts by weight of acesulfame potassium, 10 parts by weight of peppermint flavoring, and 1 part by weight of sodium bicarbonate.

[0067] Example 1 also provides a method for preparing a mouth-held product, which uses the mouth-held composition of Example 1 to prepare the mouth-held product, specifically including: ① Drying and grinding: Dry the corn silk at 60℃, control the moisture content to ≤5%, grind it with a grinder, sieve it, and take corn silk powder between 30 mesh and 150 mesh. ② Dissolving: Add an appropriate amount of water to dissolve nicotine, flavoring, cooling agent, sweetener, and pH adjuster to obtain a mixed solution; ③ Dry mixing: Add microcrystalline cellulose and corn silk powder to a wet granulation pot, mix evenly, set the stirring speed to 150 rpm, and the mixing time to 2 min; ④ Wet granulation: Slowly pour the solution from ② into the wet granulation pot, set the stirring speed to 150 rpm, the cutter speed to 1000 rpm, and the granulation time to 5 min, control the appropriate wet particle size, and keep the moisture content of the particles at 15% for later use; ⑤Bag packaging: The granules in material ④ are filled into fiber bags. The longitudinal sealing temperature is 245℃, the front sealing temperature is 165℃, and the rear sealing temperature is 165℃ to obtain the oral product (nicotine bag). ⑥ Spray water afterward: Spray water through a spray bottle to increase the moisture content of the nicotine granules in the nicotine bag to 40%, 45%, and 50%.

[0068] Examples 2-6 and Comparative Example 1 Oral products were prepared according to the method of Example 1. The difference between Examples 2-6 and Comparative Example 1 and Example 1 is that the content of each component in the oral composition is different from that in Example 1, as shown in Table 1. Everything else is the same as in Example 1.

[0069] Table 1 Formulation of Oral Compositions for Examples and Comparative Examples

[0070] Note: The content of each component in Table 1 is in parts by mass.

[0071] The properties of the nicotine bags in the examples and comparative examples were evaluated by visual inspection and tactile examination after unpacking. The results are shown in Table 2.

[0072] Table 2. Properties of the oral products of the examples and comparative examples

[0073] The taste of the nicotine pouches prepared in the examples and comparative examples was evaluated after oral use, and the results are shown in Table 3.

[0074] Table 3. Oral position evaluation results of oral products in the examples and comparative examples.

[0075] As can be seen from Tables 1, 2 and 3, when the content of corn silk particles in the oral composition is not less than 10 parts by weight, it can better retain moisture and does not clump, has good softness and is more comfortable.

[0076] Dissolution curve experiments were conducted on the nicotine bags prepared in the examples, and the specific methods are as follows: Equipment: Dissolution apparatus - paddle method; Samples: Nicotine bags prepared in Examples 1-6, wherein the moisture content of the oral particles in the nicotine bags in Examples 1-6 was 40%; Dissolution medium: pH 6.8 artificial saliva, 500ml; Sampling points: 0.5min, 1min, 2min, 5min, 10min, 15min, 20min, 30min, 40min, 60min; Test conditions: heating temperature 37℃, rotation speed 50r / min; Analytical method: Nicotine content was detected by high performance liquid chromatography, and nicotine release was calculated; The test results are shown in Table 4.

[0077] Table 4 Comparison of nicotine release levels in the examples

[0078] As shown in Table 4, the release rate and amount of nicotine initially increased and then decreased with increasing corn silk content in the oral composition. In Examples 1-5, the nicotine release gradually increased with increasing corn silk content; however, with further increases in corn silk content, the nicotine release in Example 6 decreased compared to Example 5. This may be because the water absorption of corn silk makes the internal filling material more loose, resulting in better release. However, excessive corn silk affects flowability and reduces mixing uniformity, which is detrimental to nicotine release. Therefore, more corn silk in the oral composition is not necessarily better. Technicians can adjust the amount of corn silk added while ensuring good flowability to achieve rapid and stable nicotine release.

[0079] Examples 1-6 show that the nicotine release rate can reach over 73% at 60 minutes, Examples 2-6 show that the release rate can reach over 86% at 60 minutes, and Examples 3-5 show that the release rate can reach over 97% at 60 minutes, indicating a more complete release.

[0080] The results in Table 4 show that when the corn silk content in the oral composition is not less than 10 parts by weight, it can accelerate the release of nicotine, allowing nicotine to be released more quickly in a shorter time, which is beneficial to improving satisfaction and enhancing the user experience of the product.

[0081] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

[0082] Furthermore, those skilled in the art will understand that although some embodiments herein include certain features included in other embodiments but not others, combinations of features from different embodiments are intended to be within the scope of this application and form different embodiments. For example, in the foregoing claims, any of the claimed embodiments can be used in any combination. The information disclosed in this background section is intended only to enhance the understanding of the general background of this application and should not be construed as an admission or in any way implying that such information constitutes prior art known to those skilled in the art.

Claims

1. A mouth-held product, characterized in that, The invention includes a mouth-held composition comprising an active agent, a filler, a flavoring agent, and water, wherein the filler comprises corn silk; The corn silk content in the oral composition is not less than 10 parts by weight.

2. The oral article according to claim 1, characterized in that, In the oral composition, the water content is 3-50 parts by weight; and / or, The corn silk refers to corn silk particles, and at least 90% of the corn silk particles have a particle size of 30 mesh to 150 mesh.

3. The oral article according to claim 1, characterized in that, The filler further includes microcrystalline cellulose; and / or, The flavoring agent includes at least one of a cooling agent, a sweetener, and an edible flavoring; and / or, The oral composition further includes a pH adjuster; and / or, The oral article also includes a permeable bag, into which the oral composition is filled.

4. The oral article according to claim 3, characterized in that, The oral composition comprises 1-20 parts by weight of an active agent, 0-65 parts by weight of microcrystalline cellulose, 10-80 parts by weight of corn silk, 0-2 parts by weight of a cooling agent, 0.1-20 parts by weight of a sweetener, 0.1-20 parts by weight of an edible flavoring, 3-50 parts by weight of water, and 0-1 parts by weight of a pH adjuster.

5. The oral article according to claim 4, characterized in that, The active agent includes at least one of nicotine and nicotine derivatives, wherein the nicotine derivatives include at least one of substituted nicotine, unsubstituted nicotine salts, and substituted nicotine salts. And / or, the sweetener comprises at least one of xylitol, sorbitol, mannitol, iodine, lactitol, maltitol, isomaltitol, hydrogenated starch hydrolysate, erythritol, maltotriol, aspartame, acesulfame potassium, sodium saccharin, sucralose, neotame, cyclamate, alitane, steviol glycosides, arabinitol, and monk fruit sweetener; And / or, the cooling agent includes at least one of WS-23, WS-3, and WS-5.

6. The oral article according to any one of claims 1-5, characterized in that, In the oral composition, the corn silk content is 15-45 parts by weight.

7. A method for preparing an oral article as described in any one of claims 1-6, characterized in that, include: A mouth-sucking composition is obtained, the mouth-sucking composition comprising an active agent, a filler, a flavoring agent, and water; Granulation was performed using the oral composition to obtain oral granules; The oral granules are placed into a permeable bag to obtain an oral product.

8. The method for preparing the oral product according to claim 7, characterized in that, The method of obtaining the oral composition includes obtaining corn silk; The process of obtaining corn silk includes the following steps: drying the corn silk raw material at a temperature of 50-70℃ so that the moisture content of the processed corn silk is less than or equal to 5%, crushing, screening and obtaining corn silk particles of the target particle size.

9. The method for preparing the oral product according to claim 8, characterized in that, The filler also includes microcrystalline cellulose; The granulation using the oral composition includes: Microcrystalline cellulose and corn silk granules were mixed under stirring conditions to obtain a mixed powder. The active agent, flavoring agent and water are mixed to prepare a mixture; The mixed powder is mixed with the mixed liquid to prepare the oral granules.

10. The method for preparing the oral product according to claim 9, characterized in that, The method for preparing the mixture further includes adding a pH adjuster.

11. The method for preparing an oral product according to claim 9 or 10, characterized in that, The mixing of the microcrystalline cellulose and the corn silk granules under stirring conditions includes: placing the microcrystalline cellulose and the corn silk granules in a wet granulation pan and stirring to mix them evenly, wherein the stirring speed is 100~200 rpm and the stirring time is 1~5 min; and / or, The step of mixing the mixed powder with the mixed liquid includes: slowly pouring the mixed liquid into the mixed powder that has been placed in a wet granulation pot, stirring and granulating, wherein the stirring speed is 100~200 rpm, the cutting speed is 500~2000 rpm, and the stirring and granulation time is 1~10 min; And / or, the moisture content of the oral granules prepared by mixing the mixed powder with the mixed liquid is controlled at 10-25%; And / or, after the oral granules are placed into a permeable bag, the method further includes: humidifying the permeable bag to bring the moisture content of the oral granules to 35-50%.

12. The method for preparing an oral product according to claim 11, characterized in that, The moisture content of the oral granules is 35%-45%.

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