A method and medicament for preventing or treating neurodegenerative diseases

The combined use of gliclazide and acetaminophen has solved the problem that existing technologies cannot effectively treat neurodegenerative diseases, and has achieved improvement and disease control in cases of olfactory impairment and cognitive dysfunction, especially in diseases related to protein aggregation such as Parkinson's disease.

CN122376602APending Publication Date: 2026-07-14PING AN SHIONOGI CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
PING AN SHIONOGI CO LTD
Filing Date
2025-01-03
Publication Date
2026-07-14

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Abstract

Disclosed is a method and a medicament for preventing or treating neurodegenerative diseases using or comprising a therapeutically effective amount of gliclazide or a pharmaceutically acceptable salt thereof or a combination of gliclazide or a pharmaceutically acceptable salt thereof and acetaminophen or a pharmaceutically acceptable salt thereof. The method and the medicament of the present invention can significantly improve symptoms such as hyposmia, cognitive dysfunction, psychotic symptoms, etc. of patients with neurodegenerative diseases that cannot be treated by existing drugs, and are particularly useful for controlling the progression of neurodegenerative diseases.
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