Dendrobium candidum free amino acid prediction failure diagnosis method

By establishing a unified diagnostic evidence intermediate quantity E and an active perturbation script, the problems of matrix interference, link anomalies, and domain offset in the detection of free amino acids in Dendrobium officinale were solved. This achieved consistent data recording and reliable prediction output throughout the entire detection process, improving the accuracy and stability of the detection.

CN122392697APending Publication Date: 2026-07-14INST OF MEDICINAL PLANTS YUNNAN ACAD OF AGRI SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF MEDICINAL PLANTS YUNNAN ACAD OF AGRI SCI
Filing Date
2026-05-15
Publication Date
2026-07-14

AI Technical Summary

Technical Problem

Existing technologies for detecting free amino acids in Dendrobium officinale suffer from problems such as sensitivity to matrix interference, lack of effective identification and diagnosis of abnormalities in the detection chain, lack of sensitive detection of domain offset, and scattered records of process data and intermediate results, resulting in insufficient prediction accuracy and stability.

Method used

A unified diagnostic evidence intermediate quantity E is established, including a version number field, a version chain verification field, and an execution license identifier field. Through process meta-data, isotope internal standard response baseline, link health, dual-channel dynamic response, structured state evidence, active perturbation response signature, domain offset fingerprint, etc., the complete recording of data and intermediate results of the entire detection task process and cross-stage consistency constraints are realized. Combined with active perturbation scripts and electrochemical response acquisition, structured state evidence is generated and consistency verification and gating judgment are performed.

Benefits of technology

It achieves complete recording of data and intermediate results throughout the entire detection task process and cross-stage consistency constraints, improves the traceability and verifiability of prediction output, enhances sensitivity to link health, domain offset and abnormal patterns, reduces the risk of misjudgment, and improves the credibility and robustness of prediction values.

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Abstract

This invention discloses a method for predicting and diagnosing the failure of free amino acid prediction in Dendrobium officinale, relating to the field of quality testing and evaluation of traditional Chinese medicine. The method establishes a unified diagnostic evidence intermediate quantity E (including a version number field, a version chain verification field, and an execution license identifier field); prepares an extract to generate an isotope internal standard response baseline; splits the extract into a raw channel extract and a counterfactual channel extract, with the counterfactual channel extract undergoing molecular imprinted adsorption microcolumn matrix weakening treatment to form the counterfactual channel treatment intensity; executes an active perturbation script on both channels, dividing the baseline window, excitation window, and recovery window, and collecting the electrochemical dynamic responses of the two channels to generate a normalized correction dynamic response; a structured state evidence encoder generates structured state evidence and performs consistency verification, generates trigger codes according to corridor threshold set gating judgment, and outputs the predicted value and prediction confidence of free amino acids in Dendrobium officinale; and generates write-back correction parameters and re-verifies them through rigid forbidden zone constraint verification using a process digital twin model.
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