一种虫白蜡高级烷醇乳状分散液及其制备方法和应用

By preparing an emulsion dispersion of higher alkanols from insect wax, the problems of sourcing and purifying higher alkanols were solved, achieving the effect of effectively reducing inflammatory factors and lipid deposition in blood vessels, thus expanding its application in the field of cardiovascular health.

CN122398765APending Publication Date: 2026-07-17INST OF HIGHLAND FOREST SCI CHINESE ACAD OF FORESTRY

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF HIGHLAND FOREST SCI CHINESE ACAD OF FORESTRY
Filing Date
2026-06-16
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

The sources of existing higher alkanol compounds vary greatly, extraction and purification are complex, and preparation costs are high, making it difficult to meet the demand for high-purity raw materials for functional formulations. Furthermore, existing drug treatments have adverse reactions, and the overall preventive effect is limited.

Method used

Using insect wax higher alkanols as the main active ingredients, combined with Spande 80 and Tween 80 emulsifiers, a stable and uniform emulsion dispersion is prepared through heating dispersion and high-speed homogenization process, which improves solubility and bioavailability.

Benefits of technology

The prepared insect wax high alkanol emulsion dispersion significantly improved solubility and bioavailability, exhibited good physical stability, and was not prone to stratification or sedimentation. It achieved the dual effects of reducing inflammatory factors and vascular lipid deposition, thus expanding its application value in the field of cardiovascular health.

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Abstract

本发明公开了一种虫白蜡高级烷醇乳状分散液及其制备方法和应用,属于生物医药技术领域。本发明所述虫白蜡高级烷醇乳状分散液,包括如下重量份原料:0.5‑1.5份虫白蜡高级烷醇、0.8‑1.0份斯潘80和1.4‑1.8份吐温80。该制剂以虫白蜡高级烷醇为主要功能活性成分,辅以斯潘80、吐温80乳化剂,经加热分散与高速均质工艺制备形成乳状分散体系,使虫白蜡高级烷醇在水相中能够充分均匀分散,显著提高了溶解性和生物利用度,物理稳定性良好,不易分层或沉降,便于储存和使用。经动物实验验证,该制剂实现降低慢性炎症反应、改善血脂代谢的功能,进一步拓展了虫白蜡高级烷醇在心血管健康领域的应用价值和使用方式。
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