单宁酸在制备预防或治疗高脂饮食导致的肥胖和 / 或相关代谢紊乱的产品中的应用

Tannic acid addresses obesity and metabolic disorders caused by high-fat diets by improving gut microbiota structure and metabolic pathways, achieving significant anti-obesity, lipid-lowering, and metabolic improvement effects, and has the potential to be developed into drugs, functional foods, or dietary supplements.

CN122398827APending Publication Date: 2026-07-17BEIJING TECH & BUSINESS UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BEIJING TECH & BUSINESS UNIV
Filing Date
2026-05-15
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Obesity and related metabolic disorders caused by a high-fat diet, especially gut microbiota imbalance, intestinal barrier damage, and metabolic endotoxemia, lack effective regulatory means with current technology.

Method used

Tannic acid can be used to improve the structure of the gut microbiota by increasing the relative abundance of Bacteroidetes, decreasing the relative abundance of Firmicutes, regulating arachidonic acid, retinol and purine metabolism, repairing the intestinal barrier, reducing pro-inflammatory factors and restoring the integrity of the intestinal barrier.

Benefits of technology

It significantly inhibits weight gain, reduces lipid deposition, improves glucose and lipid metabolism, lowers serum inflammatory factors, restores gut microbiota diversity, corrects metabolite disorders, and has anti-obesity and lipid-lowering effects, while protecting liver function.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明涉及生物医药及功能食品技术领域,具体涉及单宁酸在制备预防或治疗高脂饮食导致的肥胖和 / 或相关代谢紊乱的产品中的应用。本发明通过动物实验证实,单宁酸能够显著抑制高脂饮食诱导的体重增长,减少肝脏和白色脂肪组织脂质沉积,改善葡萄糖耐量和胰岛素敏感性,降低血清甘油三酯、总胆固醇及低密度脂蛋白胆固醇水平,抑制促炎因子释放,修复肠道屏障完整性,调节肠道微生物群结构,并调控血清代谢物;这为改善和控制肥胖提供了新思路,因此可将单宁酸添加作为药物、功能食品或膳食补充剂等产品。
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