Application of oyster polysaccharide in prevention and treatment of ischemia-reperfusion injury

By using oyster polysaccharides as the active ingredient, products for the prevention and treatment of myocardial ischemia-reperfusion injury were prepared, which solved the problem of insufficient regulation of myocardial ischemia-reperfusion injury in existing technologies, achieved significant prevention and treatment effects, and provided a brand-new natural drug option.

CN122398849APending Publication Date: 2026-07-17CHINA AGRI UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CHINA AGRI UNIV
Filing Date
2026-06-15
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Current technology has not fully elucidated the regulatory effect of oyster polysaccharides on myocardial ischemia-reperfusion injury. Ischemia-reperfusion injury is a key bottleneck in cardiac pathological remodeling and heart failure, and early intervention is needed to regulate inflammation and oxidative stress.

Method used

Products for the prevention and treatment of myocardial ischemia-reperfusion injury are prepared using oyster polysaccharides as the sole active ingredient. These products include improving cardiac function, reducing myocardial cell damage, and protecting mitochondrial structure and energy metabolism. The products are administered via oral or injection routes.

Benefits of technology

It significantly improves cardiac structural and functional damage, reverses cardiac dysfunction, reduces myocardial infarction area, regulates oxidative stress, and enhances myocardial energy metabolism, providing a novel natural drug candidate for the prevention and treatment of cardiac ischemia-reperfusion injury.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明提供了牡蛎多糖在防治缺血再灌注损伤中的应用,通过动物实验证明了牡蛎多糖可显著预防和治疗心脏缺血再灌注损伤,能有效改善心功能、减轻心肌病理损伤并缩小心脏梗死面积,同时调节血清心肌酶与抗氧化水平,保护线粒体结构并改善心肌能量代谢,拓展了牡蛎多糖的应用场景,为开发防治心脏缺血再灌注损伤的新型药物提供了新的技术方案。
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