一种抗组胺、抗过敏的中药复方外用制剂

By combining traditional Chinese medicines such as purslane and Bidens pilosa with modern preparation technology, a multi-level synergistic system is constructed, which solves the shortcomings of oral antihistamines and the limitations of topical products in existing technologies. It achieves the effects of rapidly relieving allergy symptoms, promoting skin repair and enhancing the skin barrier. It is a topical compound preparation of traditional Chinese medicine suitable for antihistamine, anti-inflammatory and skin repair.

CN122398889APending Publication Date: 2026-07-17SICHUAN YUMEIJI TECHNOLOGY CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SICHUAN YUMEIJI TECHNOLOGY CO LTD
Filing Date
2026-06-17
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing oral antihistamines have a slow onset of action and long-term use may cause drowsiness and systemic metabolic burden. Topical products have a single mechanism of action, short local residence time, insufficient ability to repair damaged skin, and poor stability. Traditional Chinese medicine compound topical preparations have limited effects in antihistamine, anti-inflammatory and skin repair.

Method used

The core antihistamine and anti-allergy system is constructed using purslane, beggar-ticks, perilla leaves and kochia fruit. Combined with centella asiatica, sedum and vitamin B5 to promote skin repair, ceramide and sodium hyaluronate are added to enhance the skin barrier. The preparation process uses pre-soaking extraction combined with secondary reflux extraction and cold addition of vitamin components to prepare topical preparations such as liquid dressings, gels, sprays or ointments.

Benefits of technology

It can quickly relieve skin itching and erythema caused by histamine, promote skin repair, enhance skin barrier function, increase local drug concentration, reduce the risks of systemic medication, and improve formulation stability and retention rate of active ingredients.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明公开一种抗组胺、抗过敏的中药复方外用制剂,包括:马齿苋、鬼针草、积雪草、景天三七、白兰、紫苏叶、地肤子、维生素B3、维生素B5、维生素E、神经酰胺、透明质酸钠及醇类溶剂;本发明采用预浸提结合二次回流提取工艺,将维生素类成分冷却后加入,经均质分散制得液体敷料、凝胶、喷雾剂、乳膏或药膏;该制剂通过抑制肥大细胞脱颗粒和组胺释放、降低炎症因子水平、促进皮肤屏障修复,实现"抗过敏‑抗炎‑促修复"的协同作用,用于缓解组胺释放引起的皮肤瘙痒、红斑、风团及过敏性皮炎,具有起效快、安全性高、稳定性好的特点。
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