A drug coated balloon catheter

By introducing biodegradable microneedles and staggered pressure-absorbing elements into the drug-coated balloon catheter, combined with an adhesion fixation layer and a rapid drug release layer, the problem of uneven adhesion between the drug-coated balloon and the irregular lesion vessel wall is solved, achieving deep penetration and uniform distribution of drugs and improving the therapeutic effect.

CN122399207APending Publication Date: 2026-07-17
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Filing Date
2026-05-19
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing drug-coated balloons cannot achieve optimal adhesion and uniform compression to irregularly diseased vessel walls during expansion, resulting in uneven drug distribution and treatment blind spots.

Method used

Design a drug-coated balloon catheter comprising a surface-covered biodegradable microneedles and an internal elastic balloon, driven by interleaved active pressure-resistant elements and control cables, combined with an adhesion fixation layer and a rapid drug release layer to promote deep drug penetration and uniform distribution.

Benefits of technology

It improves the penetration efficiency and targeting depth of drugs in the blood vessel wall, reduces long-term foreign body residue and inflammatory stimulation, ensures uniform drug delivery in irregular lesion areas, and reduces treatment blind spots.

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Abstract

本发明涉及一种药物涂层球囊导管,包括表面覆盖有活性药物涂层的药物涂层球囊以及推送导管、可降解微针以及弹性球囊;还包括第一抵压元件和第二抵压元件、多个控制件以及通过限位件设置的内腔通管。本发明在药物涂层球囊内部设计弹性球囊,并通过推送导管内的第一路控制线缆‌、第二路控制线缆‌驱动弹性球囊内的第一抵压元件和第二抵压元件进行‌交错式往复活动;在药物涂层球囊扩张工作区表面,配合可降解微针,使可降解微针微针能够刺入血管壁的内膜层甚至中膜,形成微观的给药通道;结合黏附固定层和快速释药层,能够将高浓度治疗药物直接输送至更深的血管壁组织,避免了仅停留在内皮表面的问题,大幅提高了药物的局部生物利用度和留存率。
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