集成神经刺激与采集的模拟前端电路及脑机系统

By employing alternating grounding and synchronous switching of signal channels in the invasive neural stimulation and acquisition system, the problem of interference between stimulation and acquisition signals was solved, achieving high-fidelity neural signal acquisition and ensuring the safety of the stimulation process and the accuracy of the acquisition.

CN122399252APending Publication Date: 2026-07-17HANGZHOU QINGSHI YONGJUN MEDICAL EQUIPMENT CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HANGZHOU QINGSHI YONGJUN MEDICAL EQUIPMENT CO LTD
Filing Date
2026-06-22
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

In invasive neural stimulation and acquisition systems, signal interference between stimulation signals and acquisition signals is difficult to suppress effectively, resulting in the system's inability to achieve high-precision neural signal acquisition.

Method used

An analog front-end circuit integrating neural stimulation and acquisition is adopted. By alternately grounding the two stimulation electrodes during the stimulation cycle and synchronously switching the on and off states of the signal channel in the signal acquisition module, the stimulation signal is prevented from coupling to the acquisition path. The H-bridge switching unit and dummy load unit are used to suppress artifact interference.

Benefits of technology

It effectively suppressed the interference of stimulation signals on the acquired signals, ensuring high-fidelity neural signal acquisition under conditions of synchronous stimulation and acquisition, and improving the safety and accuracy of acquisition.

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Abstract

本申请涉及生物电信号处理技术领域,公开了一种集成神经刺激与采集的模拟前端电路及脑机系统,其中,模拟前端电路包括多路电极、刺激模块和信号采集模块,刺激模块和信号采集模块分别连接多路电极,电极中的任意两个被选作刺激电极,其余电极为采集电极;其中,刺激模块被配置为控制两个刺激电极在刺激周期内交替接地,且使未接地的刺激电极输出刺激信号;信号采集模块包括与电极一一对应的多个信号通道,信号采集模块被配置为关断刺激电极对应的信号通道,并同步于刺激周期切换采集电极对应的信号通道的通断状态,以在非刺激周期获取响应于刺激信号的生理信号。本申请能够有效抑制刺激伪迹,实现高保真生理信号采集。
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