Monoterpene-based monomethylenedication quaternary salt, its synthesis method and application in bacteriostasis

Abstract

The application belongs to the technical field of natural product organic synthesis and antibacterial technology, and discloses monoterpenyl monomethylene gemini quaternary ammonium salt, a synthesis method thereof and application thereof in bacteriostasis. Eight monoterpenyl monomethylene gemini quaternary ammonium salt compounds are synthesized from tertiary amines containing hydrogenated nopol and tetrahydrogeranyl and imidazole, the synthesis method is simple, and the product yield and purity are relatively high. The biological activity test results show that the compounds have good bacteriostatic effects on various fungi, oomycetes and bacteria, and the partial bacteriostatic rates reach 100%. The compounds can be simultaneously used in crop disease control and food industry disinfection fields, realize "one drug for multiple uses", effectively reduce agricultural production cost, reduce the amount of pesticide used, and have wide industrialization application prospects in the fields of green agriculture and food safety.

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