一种从发酵液中分离纯化L-岩藻糖的方法
By optimizing the separation and purification process through techniques such as ceramic membrane filtration, continuous ion exchange system and sequential simulated moving bed chromatography, the problem of separating IPTG and L-fucose in fermentation broth was solved, and the production of high-yield and high-purity L-fucose was achieved.
CN122404433APending Publication Date: 2026-07-17HEFEI MICROHE HEXAGON BIOTECHNOLOGY CO LTD
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- HEFEI MICROHE HEXAGON BIOTECHNOLOGY CO LTD
- Filing Date
- 2026-03-27
- Publication Date
- 2026-07-17
AI Technical Summary
Technical Problem
Existing technologies are insufficient for efficiently separating IPTG and L-fucose in fermentation broth, resulting in low yield and purity of L-fucose and excessive IPTG residues, which affects food safety.
Method used
By employing steps such as ceramic membrane filtration, continuous ion exchange system, sequential simulated moving bed chromatography, and organic membrane filtration, combined with specific resins and drying techniques, the separation and purification process is optimized to achieve efficient separation of IPTG and L-fucose.
Benefits of technology
High-yield and high-purity L-fucose was obtained with IPTG residue below 0.1 mg/kg and transmittance >98%, significantly improving separation and purification efficiency and product quality.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure CN122404433A_ABST
Abstract
本发明涉及分离纯化技术领域，尤其涉及一种从发酵液中分离纯化L‑岩藻糖的方法。本发明提供了一种从复杂发酵液体系同步实现IPTG和L‑岩藻糖分离的方法。本发明通过优化分离纯化路线设计，经过过滤、脱色、浓缩、连续离子交换系统脱盐、顺序式模拟移动床色谱分离、有机膜过滤、干燥等步骤，可从发酵液中高效获得高纯度的L‑岩藻糖。
Need to check novelty before this filing date? Find Prior Art