一种具有抗氧化和抗衰老的中性黄精多糖及提纯方法与应用
By employing ultrasonic water extraction, multi-stage alcohol precipitation, and synergistic purification using anion exchange column and dextran gel column, the extraction process of Polygonatum polysaccharides was optimized. This solved the problems of numerous impurities and low levels of active ingredients in existing extraction techniques, resulting in high-purity, high-activity neutral Polygonatum polysaccharides suitable for preparing antioxidant and anti-aging drugs or health products.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- HUNAN AGRI UNIV
- Filing Date
- 2026-05-18
- Publication Date
- 2026-07-17
AI Technical Summary
Existing extraction technologies for Polygonatum polysaccharides lack specificity, resulting in numerous impurities during the extraction process, low content of effective active ingredients, and insufficient pharmacological activity and bioavailability, making it difficult to meet the high-quality requirements of pharmaceuticals and health products.
The extraction process was optimized by using ultrasonic water extraction, multi-stage alcohol precipitation, and synergistic purification with anion exchange column and dextran gel column, combined with fractional alcohol precipitation and enzymatic extraction, to retain the highly active components of Polygonatum odoratum and obtain neutral Polygonatum odoratum polysaccharide with strong antioxidant capacity and uniform composition.
This study achieved high purity, high activity, and good water solubility of Polygonatum polysaccharides, significantly enhancing their antioxidant and anti-aging properties and broadening their application potential in the pharmaceutical and health product fields.
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Figure CN122404587A_ABST