mass spectrometer
By generating a second applied voltage in the mass spectrometer to suppress the potential gradient, the problem of ion retention during ionization switching is solved, improving analytical accuracy and image clarity, especially when switching between atmospheric pressure MALDI and ESI sources.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SHIMADZU SEISAKUSHO LTD
- Filing Date
- 2024-01-12
- Publication Date
- 2026-07-17
AI Technical Summary
When using mass spectrometers with different ionization methods, especially when switching from an atmospheric pressure MALDI source to an ESI source, the sample boundary is easily blurred in imaging mass spectrometry analysis, resulting in reduced analytical accuracy. This is because the retention of ions in the ion transport optical system causes a time delay.
By saving the information of the first applied voltage and generating a second applied voltage to suppress the potential rise gradient when needed, the electrode voltage is adjusted to suppress ion retention and improve analytical accuracy.
When using different ionization methods, suppressing the potential rise gradient in the ion transport optical system reduces ion retention and improves the resolution and clarity of imaging mass spectrometry analysis.
Smart Images
Figure CN122422982A_ABST