Aortic dissection rupture closure device

Abstract

The application provides an aortic dissection rupture sealing device, which comprises a body having a hollow flow channel extending along the axial direction of the body, the hollow flow channel penetrating the rupture for conducting the true lumen of the aorta and the branch blood vessel, and the body being used for connecting a stent located in the branch blood vessel; and an anchoring part arranged on the body and surrounding the hollow flow channel, and anchored to the surrounding intima at the rupture, so as to prevent the fluid from conducting between the true lumen and the false lumen formed at the rupture. By using the above scheme, the rupture sealing effect can be improved, the continuous expansion of the false lumen caused by the incomplete rupture sealing and the residual liquid leakage can be avoided, and the blood supply stability of the branch blood vessel can be ensured, so that the blood supply demand of the internal organs, the spinal cord and the like supplied by the branch blood vessel can be met.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a sealing device for aortic dissection rupture. Background Technology

[0002] Aortic dissection (AD) is a serious cardiovascular disease. The aorta consists of the intima, media, and adventitia from the inside out. An aortic dissection tear occurs when a tear appears in the intima of the aorta, allowing blood to enter the media and causing separation between the intima and adventitia. This separation extends along the long axis of the aorta, creating a true lumen and a false lumen. The true lumen is the space defined by the intima, while the false lumen is the space formed between the intima and adventitia due to the separation.

[0003] For example, after thoracic endovascular aortic repair (TEVAR), the incidence of post-dissection thoracic and abdominal aortic aneurysms is high, with distal residual ruptures being the main cause of persistent blood flow in the false lumen. Treatment of aortic dissection is a complex process involving various treatment strategies and techniques. The difficulty in treating aortic dissection also lies in: 1. Severe stenosis of the aortic true lumen, with narrowing of the distal true lumen of the aortic dissection, often accompanied by tortuosity, making stent deployment difficult in later stages and superselective placement of branch arteries challenging. 2. The distal rupture often involves visceral vessels; in chronic aortic dissection, the distal rupture is often located in the visceral branch area. Covering the opening of visceral arteries will cause visceral ischemia; sealing such ruptures requires visceral artery reconstruction. 3. There may be visceral branch arteries opening into the false lumen or accompanied by branch artery dissection. When the distal tear of a chronic aortic dissection involves a branch artery, the branch may open into a false lumen, and the dissection may extend to the distal end of the branch artery, affecting the blood supply to the branch artery. Patients may experience abdominal pain, abdominal distension, and weight loss due to difficulty eating caused by chronic renal insufficiency and chronic intestinal ischemia.

[0004] Existing treatment methods for aortic dissection tears have several drawbacks, including complex procedures, obstruction of branch vessels affecting other organs, spinal cord ischemia, and incomplete closure of the tear leading to residual leakage and continuous expansion of the false cavity. Summary of the Invention

[0005] The technical problem solved by the embodiments of the present invention is that existing methods of sealing ruptures are complicated to operate, obstruct branch vessels and affect other organs, cause spinal cord ischemia, and cause residual leakage due to incomplete sealing of the rupture, resulting in continuous expansion of the false cavity.

[0006] To address the aforementioned technical problems, this invention provides a sealing device for aortic dissection ruptures, comprising: a body having a hollow channel extending axially along the body, the hollow channel penetrating the rupture to facilitate communication between the true lumen of the aorta and branch vessels, the body being used to connect a stent located in the branch vessels; and an anchoring portion disposed on the body and surrounding the hollow channel, and anchored to the intima surrounding the rupture site to prevent fluid communication between the true lumen and the false lumen formed at the rupture site.

[0007] Optionally, the anchoring portion includes: a first fixing portion surrounding the hollow flow channel, the size of the first fixing portion being larger than the size of the opening, and abutting against the inner membrane on the side facing the true cavity.

[0008] Optionally, the anchoring portion further includes: a second fixing portion surrounding the hollow flow channel, wherein the size of the first fixing portion is larger than the size of the tear, and abuts against the inner membrane on the side facing the false cavity; and a clamping portion located between the first fixing portion and the second fixing portion along the radial direction of the body, wherein the size of the clamping portion is smaller than the size of the first fixing portion and the second fixing portion, the tear is fitted onto the clamping portion, and the inner membrane at the tear is clamped in the clamping space between the first fixing portion and the second fixing portion.

[0009] Optionally, the clamping space contracts radially away from the body.

[0010] Optionally, the body has a retracted state and a blocked state. The body is configured to deform along the axial and radial directions from the retracted state and switch to the blocked state. The anchoring part is formed after the body deforms and switches to the blocked state.

[0011] Optionally, the first fixing part has a first inclined surface facing the second fixing part; and / or the second fixing part has a second inclined surface facing the first fixing part.

[0012] Optionally, the angle between the first inclined surface and the radial direction of the body is in the range of [15°, 60°]; and / or the angle between the first inclined surface and the radial direction of the body is in the range of [30°, 45°]; and / or the angle between the second inclined surface and the radial direction of the body is in the range of [15°, 60°]; and / or the angle between the second inclined surface and the radial direction of the body is in the range of [30°, 45°]; and / or the area where the first inclined surface connects to the clamping part has a curved transition; and / or the area where the second inclined surface connects to the clamping part has a curved transition.

[0013] Optionally, an elastic adjustment part is provided around the clamping part, and the elastic adjustment part is adjustable in size along the radial direction.

[0014] Optionally, the body includes a skeleton formed by a woven structure and / or a skeleton formed by a cutting process.

[0015] Optionally, the body may be configured as a multi-layer structure; and / or the clamping part may be a multi-layer structure; and / or the first fixing part may be a single-layer structure; and / or the second fixing part may be a single-layer structure.

[0016] Optionally, the body is provided with a flow-blocking part.

[0017] Optionally, the body is provided with a connecting part for connecting a stent placed in the branch blood vessel, wherein the hollow flow channel is in fluid communication with the stent.

[0018] Optionally, one end of the stent is located within the hollow flow channel, and the other end of the stent is located within the branch vessel.

[0019] Optionally, the connecting portion includes a protrusion located within the hollow flow channel; and / or the connecting portion includes an elastic portion located within the hollow flow channel and connected to the inner wall of the body; and / or the connecting portion includes a cylindrical structure located downstream of the anchoring portion, the cylindrical structure communicating with the hollow flow channel, and the diameter of the cylindrical structure gradually decreasing along the direction from the anchoring portion to the connecting portion; and / or the connecting portion includes a flexible membrane located within the hollow flow channel, the flexible membrane having planes intersecting the axial direction, and the flexible membrane having a perforation for communicating between the support and the hollow flow channel, the size of the perforation being adjustable in the radial direction of the body.

[0020] Optionally, the protrusion extends in a direction opposite to or perpendicular to the fluid flow direction within the hollow channel.

[0021] Optionally, the hollow channel is divided into multiple sub-channels along the axial direction, each sub-channel being used to connect a corresponding branch blood vessel.

[0022] Compared with the prior art, the technical solution of the embodiments of the present invention has the following beneficial effects: The aortic dissection closure device provided in this application includes a main body and an anchoring part. The anchoring part anchors the closure device to the intima surrounding the rupture, preventing fluid communication between the true lumen and the false lumen formed at the rupture site, thus avoiding blood from the true lumen from entering the false lumen. A hollow flow channel extending axially along the main body penetrates the rupture, enabling communication between the true lumen of the aorta and its branch vessels, ensuring blood supply from the true lumen of the aorta to the branch vessels. This improves the rupture closure effect, avoids residual leakage due to incomplete rupture closure leading to continuous expansion of the false lumen, and ensures stable blood supply to the branch vessels, which is beneficial for meeting the blood supply needs of internal organs and the spinal cord supplied via the branch vessels. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the structure of a sealing device for an aortic dissection rupture according to an embodiment of the present invention; Figure 2 yes Figure 1 A schematic diagram along the direction of section line AA; Figure 3 This is a schematic diagram of another aortic dissection rupture sealing device in an embodiment of the present invention; Figure 4 yes Figure 3 A schematic diagram along the BB direction of the cross section; Figure 5 This is a cross-sectional view of another aortic dissection rupture sealing device in an embodiment of the present invention; Figure 6 This is a schematic diagram of a connecting part in an embodiment of the present invention; Figure 7 This is a schematic diagram of another connecting part in an embodiment of the present invention; Figure 8 This is a schematic diagram of another connecting part in an embodiment of the present invention; Figure 9 This is a schematic diagram of another connecting part in an embodiment of the present invention; Figure 10 This is a schematic diagram of the aortic dissection rupture in an embodiment of the present invention; Figure 11 This is a schematic diagram of the sealing device for aortic dissection rupture in an embodiment of the present invention. Detailed Implementation

[0024] To make the above-mentioned objectives, features and beneficial effects of the embodiments of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0025] See Figures 1 to 11 This invention provides a sealing device 100 for aortic dissection rupture (hereinafter referred to as sealing device), which includes a body 1 and an anchoring portion 2 disposed on the body 1. A hollow flow channel 11 extends along the axial direction y of the body 1. In use, the hollow flow channel 11 penetrates the rupture 204 to connect the true lumen 205 of the aorta 200 to a branch vessel 300. The body 1 is used to connect a stent 400 located in the branch vessel 300. The anchoring portion 2 surrounds the hollow flow channel 11 and is anchored to the intima 201 surrounding the rupture 204 to prevent fluid communication between the true lumen 205 and the false lumen 206 formed at the rupture 204. It should be noted that the positive and negative directions of x in the figure are radial, and are referred to as radial x in this document. The positive and negative directions of y are axial, and are referred to as axial y in this document.

[0026] Using the above scheme, the anchoring part 2 can anchor the sealing device 100 to the intima 201 at the rupture 204, thereby preventing fluid communication between the true lumen 205 and the false lumen 206 formed at the rupture 204. This prevents blood from the true lumen 205 from entering the false lumen 206, avoiding further expansion of the false lumen 206 and aiding in its recovery and shrinkage. The hollow flow channel 11, extending along the y-axis of the body 1, penetrates the rupture 204, enabling communication between the true lumen 205 of the aorta 200 and the branch vessels 300. This ensures blood supply from the true lumen 205 of the aorta to the branch vessels 300, guaranteeing the stability of the blood supply to the branch vessels 300. This improves the sealing effect on the rupture 204, preventing residual leakage due to incomplete sealing of the rupture 204 and subsequent continuous expansion of the false lumen, while ensuring the stability of the blood supply to the branch vessels 300. This is beneficial for meeting the blood supply needs of internal organs and the spinal cord supplied by the branch vessels.

[0027] In a specific implementation, the anchoring part 2 includes a first fixing part 21. The size of the first fixing part 21 is larger than the size of the opening 204. The first fixing part 21 surrounds the hollow flow channel 11 and abuts against the side of the inner membrane 201 facing the true cavity 205. In this way, the sealing device 100 is attached to the inner membrane 201 by the first fixing part 21, thereby improving the fixing stability of the sealing device 100 and reducing the probability of the sealing device 100 falling off from the opening 204.

[0028] The anchoring part 2 further includes a second fixing part 22 and a clamping part 23. The second fixing part 22 surrounds the hollow flow channel 11, and its size is larger than that of the tear 204, abutting against the side of the inner membrane 201 facing the false cavity 206. The clamping part 23 is located between the first fixing part 21 and the second fixing part 22, along the radial x of the body 1, and its size is smaller than that of the first fixing part 21 and the second fixing part 22. The tear 204 is fitted onto the clamping part 23, and the inner membrane 201 at the tear 204 is clamped within the clamping space 24 between the first fixing part 21 and the second fixing part 22. The size of the clamping part 23 is smaller than that of the tear 204 to achieve an edge seal of the tear 204, preventing blood from entering the false cavity 206 through the gap between the clamping part 23 and the edge of the tear 204.

[0029] The inner membrane 201 is held against the side facing the true cavity 205 by the first fixing part 21, and the inner membrane 201 is held against the side facing the false cavity 206 by the second fixing part 22. The tear 204 is fitted onto the clamping part 23 to improve the fixing firmness of the anchoring part 2 at the tear 204 and further reduce the probability of the sealing device 100 falling off. The inner membrane 201 at the tear 204 is clamped in the clamping space 24 between the first fixing part 21 and the second fixing part 22, which can prevent the tear size of the inner membrane 201 near the tear 204 from further increasing.

[0030] In some embodiments, the clamping space 24 contracts along the radial x of the body 1, toward a direction away from the body 1. In other words, the distance between the first fixing part 21 and the second fixing part 22 gradually increases along the radial x of the body 1, toward the center of the body 1. The first fixing part 21 and the second fixing part 22 are clamped in a region away from the edge of the tear 204, so that the force exerted by the first fixing part 21 and the second fixing part 22 on the inner membrane 201 when fixing the sealing device is away from the edge of the tear 204, thereby protecting the edge of the tear 204 and preventing further tearing of the tear 204 in the edge region, which would lead to a further increase in the size of the tear 204.

[0031] Furthermore, at least the edge portion of the first fixing part 21 and at least the edge region of the second fixing part 22 are in contact with the inner membrane 201. In this way, the sealing effect on the rupture 204 is improved, and the fixing firmness of the sealing device 100 is also improved.

[0032] In some embodiments, the body 1 has a retracted state and a blocked state. The body 1 is configured to deform from the retracted state along the axial direction y and the radial direction x, and switch to the blocked state. The anchoring part 2 is formed after the body 1 deforms and switches to the blocked state.

[0033] The body 1 can be made of shape memory alloy. Shape memory alloy has shape memory effect. The shape of the anchoring part 2 in the blocking state can be configured to its original shape. When the blocking device 100 is assembled in place, the blocking device 100 can be restored from the retracted state to the original state by applying force (expanding the body 1 through the expansion structure) or other means.

[0034] The body 1 can also be made of polymer materials or biodegradable materials. In this case, the shape of the anchoring part 2 or the original state of the sealing device 100 can be maintained in various ways to ensure the sealing effectiveness and stability of the sealing device 100.

[0035] Method 1 involves using a biodegradable material that can recover to its original shape under specific conditions, i.e., a biodegradable material with shape memory function. Alternatively, a material with shape memory function can be added to the biodegradable material used to prepare the sealing device 100, thereby using the material with shape memory function to drive the molding of the entire body 1 to obtain the anchoring part 2. It should be noted that, in this case, the original state of the sealing device 100 is taken as the state when effective sealing occurs.

[0036] Method Two: An auxiliary forming mechanism is used to assist the main body 1 in forming the anchoring part 2, allowing the main body 1 to switch from a retracted state to its original state, thereby effectively sealing the breach 204. The auxiliary forming mechanism can be withdrawn after the anchoring part 2 is formed on the main body 1. For example, the auxiliary forming mechanism can be a forming line that passes through the main body 1. When the main body 1 is in the retracted state, the forming line reaches the breach 204 along with the main body 1. After the sealing device 100 is released (also known as expansion), the forming line is pulled back, and the forming line assists the main body 1 in forming the anchoring part 2 before being withdrawn.

[0037] Method 3: The sealing device 100 is equipped with an adhesive component. The adhesive component can achieve adhesion after a set time following unsealing; or after a certain period of contact with blood; or the adhesive component can be sealed with a sealing layer before the sealing device 100 is released, and after the sealing device 100 is released, the sealing layer is torn or damaged, exposing the adhesive surface of the adhesive component, thus achieving adhesion. This method can bond a portion of the anchoring part 2 of the sealing device 100 to the inner membrane, and can also bond components at different locations of the sealing device 100 to maintain the formed anchoring part 2.

[0038] Method 4: The sealing device 100 has a riveting component. After the sealing device 100 is released, that is, after the body 1 is formed to obtain the anchoring part 2, at least the component corresponding to the anchoring part 2 in the sealing device 100 is riveted to improve the shape stability of the anchoring part 2 and ensure the sealing effectiveness of the sealing device 100.

[0039] Method 5: The sealing device 100 has a magnetic component. During the release process of the sealing device 100, the magnetic component attracts the corresponding magnetic conductor to maintain the shape of the anchoring part 2, thereby ensuring the stability of the shape of the formed anchoring part 2 and guaranteeing the sealing effectiveness of the sealing device 100. A portion of the body 1 has a magnetically conductive structure that can serve as a magnetic conductor and attract the magnetic component. Alternatively, a magnetic conductor can be additionally provided at a corresponding position on the body 1.

[0040] Method 6: The sealing device 100 has a traction locking structure. After the sealing device 100 is formed to obtain the anchoring part 2, the traction locking structure is locked by interference fit or snap-fit ​​to maintain the shape of the formed anchoring part 2 and improve the stability of the shape of the anchoring part 2.

[0041] It is understandable that the shape of the anchoring part 2 obtained by molding can also be maintained in other ways, which will not be listed here.

[0042] The radial dimension of the main body 1 in the retracted state is smaller than that in the occlusion state. During placement, the main body 1 is in the retracted state, which makes the occlusion device 100 smaller in size, so that the occlusion device 100 can be more easily inserted into the aorta 200, and can be moved within the aorta 200 and placed smoothly into the rupture 204 region.

[0043] When the retracted body 1 is placed in the area of ​​the opening 204, the body 1 passes through the opening 204, the relative position of the body 1 and the opening 204 is adjusted, the body 1 expands, expands radially (x) and contracts axially (y), forming an anchoring part 2. For example, the anchoring part 2 is formed by a first fixing part 21, a second fixing part 22, and a clamping part 23. The radial dimensions of the first fixing part 21, the second fixing part 22, and the clamping part 23 of the body 1 can be configured according to the size of the opening 204, the thickness of the inner membrane 201, etc.

[0044] In some embodiments, the anchoring portion 2 is integrally formed with the body 1 as part of the body 1. The body 1 expands radially and contracts axially to form the anchoring portion 2.

[0045] The retracted body 1 can be cylindrical to fit the shape inside the blood vessel, facilitating the movement of the occlusion device 100 within the aorta 200.

[0046] In other embodiments, the anchoring part 2 can be independent of the body 1 and connected to the body 1. The anchoring part 2 also has a retracted state and an extended state. During the placement of the sealing device 100, both the anchoring part 2 and the body 1 can be in the retracted state. When the position of the anchoring part 2 corresponds to the position of the body 1, the body 1 and the anchoring part 2 are expanded, so that the clamping part 23 in the anchoring part 2 supports the edge of the rupture 204, and the first fixing part 21 and the second fixing part 22 respectively abut against the two sides of the inner membrane 201, so that the anchoring part 2 in the extended state is anchored on the inner membrane 201.

[0047] In some non-limiting embodiments, the first fixing part 21 and the second fixing part 22 may be disc-shaped. For example, the first fixing part 21 and the second fixing part 22 may be disc-shaped.

[0048] In some embodiments, the first fixing part 21 has a first inclined surface 211 facing the second fixing part 22.

[0049] In some embodiments, the second fixing part 22 has a second inclined surface 221 facing the first fixing part 21.

[0050] Along the radial direction x of the body 1, from the body 1 toward a direction away from the body 1, the first inclined surface 211 and the second inclined surface 221 extend toward each other. The space between the first inclined surface 211 and the second inclined surface 221 is the clamping space 24.

[0051] In some embodiments, the area where the first inclined surface 211 connects with the clamping portion 23 has a curved transition.

[0052] In some embodiments, the area where the second inclined surface 221 connects with the clamping portion 23 has a curved transition.

[0053] In some embodiments, the angle between the first inclined surface 211 and the radial direction of the body 1 ranges from [15°, 60°].

[0054] In some embodiments, the angle between the first inclined surface 211 and the radial direction of the body 1 is in the range of [30°, 45°].

[0055] In some embodiments, the angle between the second inclined surface 221 and the radial direction of the body 1 ranges from [15°, 60°].

[0056] In some embodiments, the angle between the second inclined surface 221 and the radial direction of the body 1 ranges from [30°, 45°].

[0057] In some embodiments, an elastic adjustment portion is sleeved around the periphery of the clamping portion 23, and the elastic adjustment portion is adjustable along the radial x dimension. This allows for the adaptation to punctures 204 of different sizes, improving the versatility of the sealing device 100. Furthermore, the edge of the puncture 204 is sleeved on the elastic adjustment portion, which improves the sealing effect on the puncture 204 and allows for flexible contact between the edge of the puncture 204 and the clamping portion 23, preventing further tearing of the edge of the puncture 204.

[0058] The body 1 includes a skeleton formed by a woven structure and / or a skeleton formed by a cutting process. For example, the entire body 1 can be a skeleton formed by a woven structure. Alternatively, the entire body 1 can be a skeleton formed by a cutting process. Yet another example is that a portion of the body 1 is a skeleton formed by a woven structure, and another portion is a skeleton formed by a cutting process. The specific structural style of the body 1 is configured according to actual needs.

[0059] In some embodiments, the body 1 may be made of metal, polymer, biodegradable material, or other materials suitable for human safety.

[0060] In some embodiments, the sealing device 100 may be a single-layer structure as a whole. The sealing device 100 may also be a multi-layer structure as a whole. The sealing device 100 may have a portion that is a single-layer structure and another portion that is a multi-layer structure. The single-layer structure includes, but is not limited to, a single-layer braided structure. The multi-layer structure includes, but is not limited to, a multi-layer braided structure.

[0061] In some embodiments, the clamping portion 23 can be a multi-layered structure. For example, the clamping portion 23 is a multi-layered braided structure. In the radial direction of the body 1, the diameter of the innermost braided structure is smaller than the diameter of the outermost braided structure. The outermost braided structure is supported by the opening 204, and the diameter of the outermost braided structure matches the size of the opening 204. The innermost braided structure can be connected to the support 400, and the diameter of the outermost braided structure matches the expanded diameter of the support 400.

[0062] The difference between the diameter of the outermost braided structure and the diameter of the innermost braided structure is the thickness of the clamping part 23. By configuring different thicknesses of the clamping part 23, sealing devices 100 of different specifications can be obtained to adapt to different sizes of breaches 204 and different types of brackets 400.

[0063] In some embodiments, the first fixing part 21 is a single-layer structure. For example, the first fixing part 21 is a single-layer woven structure.

[0064] In some embodiments, the second fixing part 22 is a single-layer structure. For example, the second fixing part 22 is a single-layer woven structure.

[0065] In some embodiments, the body 1 is provided with a flow-blocking portion 3. The flow-blocking portion 3 can prevent blood from seeping out of the hollow channel 11, so as to ensure the blood flow supplied to the branch blood vessel 300 through the hollow channel 11.

[0066] In some non-limiting embodiments, the flow-blocking portion 3 may be a flow-blocking membrane. This application does not limit the specific material of the flow-blocking portion 3.

[0067] In some non-limiting embodiments, the flow-blocking part 3 can be connected to the body 1 by means of stitching, hot pressing (e.g., double-sided hot pressing), or by means of dip coating.

[0068] The flow-blocking part 3 can be disposed on the inner wall surface, outer wall surface, fill the gaps in the body 1, or be embedded in the body 1. The relative positional relationship between the flow-blocking part 3 and the body 1 is related to their bonding method. Specifically, when the flow-blocking part 3 is connected to the body 1 by stitching, the flow-blocking part 3 can be located inside, outside, or embedded in the body 1; that is, the flow-blocking part 3 can be connected to the inner wall surface or the outer wall surface of the body 1. When the flow-blocking part 3 is connected to the body 1 by hot pressing, the flow-blocking part 3 is located on the inner wall surface or the outer wall surface, and the interface between the flow-blocking part 3 and the body 1 can be physically fused and bonded. When the flow-blocking part 3 is bonded to the body 1 by dip coating, the gaps in the flow-blocking part 3 fill the pores of the body 1, achieving the flow-blocking effect by filling the pores.

[0069] It is understandable that when the blocking device 100 does not have the flow-blocking part 3, the blood can be blocked by the structure of the body 1. For example, the body 1 has a multi-layer dense mesh woven structure, and the blood flow is blocked by the density of the sealing woven structure.

[0070] In a specific implementation, the main body 1 is provided with a connecting portion. This connecting portion is used to connect a stent 400 placed within the branch blood vessel 300, wherein the hollow flow channel 11 is fluidly connected to the hollow portion of the stent 400. Connecting the stent 400 to the main body 1 via the connecting portion improves the connection strength between the stent 400 and the main body 1, preventing the stent 400 from dislodging due to shrinkage of the false lumen 206 or vascular pulsation. The stent 400 within the branch blood vessel 300 can expand the branch blood vessel 300 to ensure smooth blood flow within it, while the hollow flow channel 11 is fluidly connected to the hollow portion of the stent 400 to ensure stable blood supply to the branch blood vessel 300.

[0071] In some embodiments, one end of the stent 400 is located within the hollow flow channel 11, and the other end of the stent 400 is located within the branch blood vessel 300.

[0072] In specific implementations, the connecting part can have various structural styles, as long as it can connect the bracket 400 to the body 1. The following describes some structural styles of the connecting part.

[0073] In some embodiments, see Figure 6The connecting part is a protrusion 41 located within the hollow flow channel. The protrusion can be multiple protrusions arranged around the hollow flow channel, or a barbed structure, etc. The protrusion can be integrally formed on the body 1, or it can be relatively independent of and connected to the body 1. The protrusion can be provided on the flow-blocking part 3. The protrusion 41 can improve the connection reliability of the bracket 400. For example, the protrusion 41 can improve the connection reliability of the bracket 400 by increasing the contact friction with the bracket 400. Alternatively, the protrusion 41 can provide connection points for the bracket 400; for example, the protrusion 41 of the barbed structure can provide a hooking point for the bracket 400, which is then hooked onto the barbed structure.

[0074] The extension direction of the protrusion 41 is opposite to or perpendicular to the fluid flow direction within the hollow flow channel 11. In particular, when the protrusion 41 is a barbed structure, each barb in the barbed structure is opposite to or perpendicular to the fluid flow direction within the hollow flow channel 11. After the support 400 is hung on the barbed structure, it can prevent the support 400 from falling off due to blood flow scouring, further improving the connection firmness of the support 400.

[0075] Furthermore, the protrusion 41 extends in a direction opposite to the fluid flow direction within the hollow channel and is inclined towards the center of the body 1. In other words, the protrusion 41 extends obliquely against the fluid flow direction within the hollow channel. This improves the connection strength of the bracket 400 while facilitating its installation.

[0076] In some embodiments, see Figure 7 The connecting portion includes an elastic portion 42 located within the hollow flow channel 11 and connected to the inner wall of the body 1. The elastic portion 42 can be made of a flexible and easily deformable material such as foam. The elastic portion 42 can be annular, and its inner diameter can be smaller than the expanded outer diameter of the support 400. The support 400 is interference-fitted to the elastic portion 42 to improve the connection strength of the support 400. Furthermore, since the elastic portion 42 is deformable, it can also adapt to supports 400s of different diameters, thereby improving compatibility with supports 400s of different diameters.

[0077] In some embodiments, see Figure 8 The connecting portion includes a cylindrical structure 43 located downstream of the anchoring portion 2, and the cylindrical structure 43 is connected to the hollow flow channel 11. The cylindrical structure 43 has a hollow portion and is connected to the hollow flow channel 11.

[0078] Furthermore, the diameter of the cylindrical structure 43 gradually decreases along the direction from the anchoring portion 2 to the connecting portion. That is, the diameter of the cylindrical structure 43 is variable along the blood flow direction. Thus, a portion of the cylindrical structure 43 can be cut off radially according to the required diameter of the stent 400, so that the diameter of the cut cylindrical structure 43 matches the stent 400. Alternatively, the cylindrical structure 43 can be folded radially, so that the diameter of the folded cylindrical structure 43 matches the stent 400.

[0079] In some embodiments, see Figure 9 The connecting part includes a flexible membrane 44 located in the hollow flow channel 11. The flexible membrane 44 has a plane intersecting the axial direction y, and the flexible membrane 44 has a hollow opening for conducting the support 400 and the hollow flow channel 11. The size of the hollow opening in the radial direction of the body 1 is adjustable to accommodate supports 400 of different diameters.

[0080] In some embodiments, the hollow flow channel 11 is divided into multiple sub-flow channels along the axial direction y, each sub-flow channel being used to connect a corresponding branch vessel 300. When the rupture 204 region involves multiple branch vessels 300, it is possible to simultaneously block the rupture 204 region and connect multiple branch vessels 300, ensuring the stability of blood supply to the multiple branch vessels 300. That is, while precisely closing the rupture 204, the blockage of the involved multiple branch vessels 300 is avoided, greatly reducing the coverage and obstruction rate of the foreign body on the healthy aorta, and reducing the risk of spinal cord ischemia or visceral ischemia.

[0081] In some non-limiting embodiments, the downstream region of the hollow channel 11 is divided into multiple sub-channels along the axial direction y. These multiple sub-channels may share the upstream region of the hollow channel 11. In other words, blood entering the hollow channel 11 is diverted downstream into the corresponding sub-channels.

[0082] It should be understood that the term "and / or" in this article is merely a description of the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A existing alone, A and B existing simultaneously, or B existing alone. Additionally, the character " / " in this article indicates that the preceding and following related objects have an "or" relationship.

[0083] In the embodiments of this application, "multiple" refers to two or more.

[0084] The descriptions of "first," "second," etc., appearing in the embodiments of this application are for illustrative purposes and to distinguish the objects being described. They have no order and do not indicate any special limitation on the number of devices in the embodiments of this application, nor do they constitute any limitation on the embodiments of this application.

[0085] While the present invention has been disclosed above, it is not limited thereto. Any person skilled in the art can make various modifications and alterations without departing from the spirit and scope of the invention; therefore, the scope of protection of the present invention should be determined by the scope defined in the claims.

Claims

1. A sealing device for aortic dissection rupture, characterized in that, include: The body has a hollow flow channel extending along the axial direction of the body, the hollow flow channel penetrating a perforation for guiding the true lumen of the aorta and branch vessels, the body for connecting a stent located in the branch vessels; An anchoring part is disposed on the body and surrounds the hollow flow channel, and is anchored to the inner membrane around the rupture to prevent fluid communication between the true cavity and the false cavity formed at the rupture.

2. The sealing device for aortic dissection rupture according to claim 1, characterized in that, The anchoring part includes: A first fixing part surrounds the hollow flow channel. The size of the first fixing part is larger than the size of the opening, and it abuts against the inner membrane on the side facing the true cavity.

3. The sealing device for aortic dissection rupture according to claim 2, characterized in that, The anchoring part further includes: A second fixing part surrounds the hollow flow channel, and the size of the second fixing part is larger than the size of the opening, abutting against the inner membrane on the side facing the false cavity; A clamping part is located between the first fixing part and the second fixing part along the radial direction of the body. The size of the clamping part is smaller than the size of the first fixing part and the second fixing part. The opening is fitted onto the clamping part, and the inner membrane at the opening is clamped in the clamping space between the first fixing part and the second fixing part.

4. The sealing device for aortic dissection rupture according to claim 3, characterized in that, Along the radial direction of the body, toward a direction away from the body, the clamping space contracts.

5. The sealing device for aortic dissection rupture according to claim 3, characterized in that, The body has a retracted state and a blocked state. The body is configured to deform along the axial direction and the radial direction from the retracted state and switch to the blocked state. The anchoring part is formed after the body deforms and switches to the blocked state.

6. The sealing device for aortic dissection rupture according to claim 3, characterized in that, The first fixing part has a first inclined surface facing the second fixing part; and / or the second fixing part has a second inclined surface facing the first fixing part.

7. The sealing device for aortic dissection rupture according to claim 6, characterized in that, The angle between the first inclined plane and the radial direction of the body ranges from [15°, 60°]; and / or The angle between the first inclined plane and the radial direction of the body ranges from [30°, 45°]; and / or The angle between the second inclined plane and the radial direction of the body ranges from [15°, 60°]; and / or The angle between the second inclined plane and the radial direction of the body is in the range of [30°, 45°]; and / or The area where the first inclined surface connects to the clamping part has a curved transition; and / or The area where the second inclined surface connects to the clamping part has a curved transition.

8. The sealing device for aortic dissection rupture according to claim 3, characterized in that, An elastic adjustment part is sleeved around the clamping part, and the elastic adjustment part is adjustable in size along the radial direction.

9. The sealing device for aortic dissection rupture according to claim 3, characterized in that, The body includes a skeleton formed by a woven structure and / or a skeleton formed by a cutting process.

10. The sealing device for aortic dissection rupture according to claim 9, characterized in that, The body can be configured as a multi-layer structure; and / or The clamping part has a multi-layer structure; and / or The first fixing part is a single-layer structure; and / or The second fixing part is a single-layer structure.

11. The sealing device for aortic dissection rupture according to claim 1, characterized in that, The main body is provided with a flow-blocking part.

12. The sealing device for aortic dissection rupture according to claim 1, characterized in that, The main body is provided with a connecting part for connecting a stent placed in the branch blood vessel, wherein the hollow flow channel is in fluid communication with the stent.

13. The sealing device for aortic dissection rupture according to claim 12, characterized in that, One end of the stent is located within the hollow flow channel, and the other end of the stent is located within the branch blood vessel.

14. The sealing device for aortic dissection rupture according to claim 12, characterized in that, The connecting portion includes a protrusion located within the hollow flow channel; and / or The connecting portion includes an elastic portion located within the hollow flow channel and connected to the inner wall of the body; and / or The connecting portion includes a cylindrical structure located downstream of the anchoring portion, the cylindrical structure communicating with the hollow flow channel, and the diameter of the cylindrical structure gradually decreasing along the direction from the anchoring portion to the connecting portion; and / or The connecting portion includes a flexible membrane located within the hollow flow channel. The flexible membrane has planes intersecting the axial direction and has a perforation for connecting the support and the hollow flow channel. The size of the perforation in the radial direction of the body is adjustable.

15. The sealing device for aortic dissection rupture according to claim 14, characterized in that, The protrusion extends in a direction opposite to or perpendicular to the fluid flow direction within the hollow channel.

16. The sealing device for aortic dissection rupture according to claim 1, characterized in that, The hollow channel is divided into multiple sub-channels along the axial direction, and each sub-channel is used to connect the corresponding branch blood vessel.

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