A cleaning-aid structure for a sequencing chip platform based on a gene sequencer

Abstract

This invention discloses a cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer, including a load-bearing plate, a cleaning tank fixedly mounted on the top of the load-bearing plate, a support plate inside the cleaning tank, a plurality of holes corresponding to the reagent needles to be cleaned on the support plate, a guide component for guiding the support plate on the load-bearing plate, a cylinder corresponding to the holes inside the cleaning tank, a cleaning tube passing through the cylinder, a flow divider groove embedded inside the cleaning tube, a spray hole on the flow divider groove, and a protective box fixedly mounted on the bottom of the load-bearing plate. This cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer, by setting up a cleaning tube, can perform all-round cleaning of the reagent needles, effectively improving the cleaning effect. The reagent is directionally sprayed onto the surface of the reagent needle through the spray hole to complete the rinsing and cleaning operation of the reagent needle. The cleaning tube rotates as a whole to achieve 360° circumferential cleaning of the reagent needle, ensuring the overall cleaning effect from all directions.

Description

Technical Field

[0001] This invention relates to the field of gene sequencing technology, specifically to a clean auxiliary structure for a sequencing chip platform based on a gene sequencer. Background Technology

[0002] During operation, the sequencing chip platform of the gene sequencer requires automated cleaning and maintenance of the internal flow path and functional components of the instrument using specialized cleaning reagents. Furthermore, each type of cleaning reagent must be stored in accordance with the instrument's reagent compartment specifications. Based on the cleaning auxiliary structure of the gene sequencer's sequencing chip platform, it is mainly used for specialized cleaning of the reagent needles used for sample extraction. This allows for rapid cleaning of the reagent needles and improves work efficiency.

[0003] The cleaning auxiliary structures equipped on existing gene sequencer sequencing chip platforms have a relatively simple cleaning mode when cleaning reagent needles, making it difficult to achieve comprehensive and effective cleaning. This can easily lead to incomplete cleaning of reagent needles and an overall cleaning effect that fails to meet usage requirements. It can also result in incomplete cleaning of residual reagents and trace biological samples on and inside the reagent needles, which can easily cause cross-contamination of samples and distortion of sequencing data. Furthermore, the overall cleanliness level is difficult to match the high precision and high cleanliness requirements of gene sequencers in actual operating conditions.

[0004] Therefore, the present invention provides a cleaning auxiliary structure for sequencing chip platforms based on gene sequencers. Summary of the Invention

[0005] The purpose of this invention is to provide a clean auxiliary structure for sequencing chip platforms based on gene sequencers, so as to solve the problems mentioned in the background art.

[0006] A cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer includes a load-bearing plate, a cleaning tank fixedly mounted on the top of the load-bearing plate, a support plate inside the cleaning tank, several holes on the support plate corresponding to the reagent needles to be cleaned, a guide component on the load-bearing plate for guiding the support plate, a cylinder corresponding to the holes inside the cleaning tank, a cleaning tube passing through the cylinder, a flow divider embedded inside the cleaning tube, a spray hole on the flow divider, a protective box fixedly mounted on the bottom of the load-bearing plate, a rotating mechanism inside the protective box for driving the cylinder to rotate, a groove at the bottom of the protective box, a power mechanism inside the groove, a drain head on the side of the cleaning tank, and a wind-powered component inside the groove.

[0007] By adopting the above scheme, after the cleaning tank is fixed in the cleaning position by the load-bearing plate, the cleaning tank is filled with cleaning reagent. During testing based on the sequencing chip platform of the gene sequencer, the reagent needle needs to draw samples to the sequencing station for detection. However, after the detection is completed, when cleaning the reagent needle is required, the position of the reagent needle is moved so that it is aligned with the corresponding hole. After the reagent needle moves down through the hole into the cleaning tank, it will insert into the cleaning cylinder, placing the reagent needle on one side of the spray nozzle. The pump is then controlled to extract the cleaning reagent from inside the cleaning tank. The extracted cleaning reagent flows into the distribution tank and, through the spray nozzle, the cleaning solution is flushed towards the sample. The reagent needle can be rinsed and cleaned. Simultaneously, a power mechanism drives a rotating mechanism, which in turn rotates the cylinder and cleaning cylinder, thereby rotating the spray nozzle. This allows for a 360-degree cleaning of the reagent needle, ensuring a thorough cleaning effect. As the reagent needle continues to move downwards, pressure is applied to the support plate, causing it to move lower. During this downward movement, a guide component guides the support plate, ensuring smooth movement. Simultaneously, the movement of the support plate applies pressure to the cleaning cylinder, causing it to move lower. The cleaning reagent inside the cleaning tank flows into the cylinder through the through-hole, allowing the reagent needle to be immersed in the reagent for cleaning.

[0008] Preferably, the guiding assembly includes a guide cylinder and a guide rod. The guide cylinder is symmetrically fixed inside the cleaning tank, the guide rod passes through the guide cylinder, and the top end of the guide rod is fixedly connected to the support plate. A drive spring is fixedly installed inside the guide cylinder, and one end of the drive spring is fixedly connected to the end of the guide rod.

[0009] By adopting the above scheme, when the support plate moves, it will drive the guide rod to slide inside the guide cylinder. Through the cooperation of the guide rod and the guide cylinder, the support plate will be guided, so that the support plate moves smoothly.

[0010] Preferably, the rotating mechanism includes a load-bearing frame, a rotating shaft, a transmission gear, a ring frame, and a connecting assembly. The load-bearing frame is fixed inside the protective box, the ring frame corresponding to the cylinder is fixed on the load-bearing frame, the rotating shaft is rotatably disposed inside the ring frame, the transmission gear is fixed on the rotating shaft and adjacent transmission gears mesh with each other, and the connecting assembly for connecting the cylinder and the rotating shaft is disposed on the rotating shaft.

[0011] By adopting the above scheme, the rotating shaft can be fixedly connected to the cylinder through the connecting component. The rotating shaft is supported by the cooperation of the load-bearing frame and the ring frame. The rotating shaft is engaged with the ring frame, which allows the rotating shaft to rotate smoothly inside the ring frame. When the rotating shaft rotates, it drives the transmission gear to rotate. When the transmission gear rotates, it drives the adjacent rotating shaft to rotate through the cooperation of adjacent transmission gears. In turn, the corresponding cylinder can be driven to rotate through the connecting component.

[0012] Preferably, the connecting assembly includes a positioning bolt, an annular groove, and a threaded hole. The annular groove is located at the top of the rotating shaft, the positioning bolt is located inside the rotating shaft, and the threaded hole is located on the cylinder, with the positioning bolt threadedly connected to the threaded hole.

[0013] By adopting the above method, after the bottom end of the cylinder enters the annular groove, the threaded hole is aligned with the positioning bolt, and the positioning bolt is rotated to connect with the threaded hole, the position of the cylinder will be positioned.

[0014] Preferably, an infusion tube is inserted inside the rotating shaft, and a rotary joint is connected to the bottom end of the infusion tube. A frame is fixedly installed on the side of the cleaning tank, and a pump is installed inside the frame. The input end of the pump is connected to the inside of the cleaning tank, and the output end of the pump is connected to the rotary joint through a pipe.

[0015] By adopting the above scheme, the pump works to extract the cleaning reagent, which, through the rotary joint, will flow into the infusion tube. The infusion tube is connected to the distribution tank through a pipe, and the cleaning reagent will then flow into the distribution tank.

[0016] Preferably, the cylinder is provided with an array of through holes, the inside of the cylinder is provided with a limiting groove, a guide plate is provided inside the limiting groove, and the guide plate is fixedly connected to the side of the cleaning cylinder, and a ring is provided at the top of the cleaning cylinder.

[0017] By adopting the above scheme, the cleaning reagent inside the cleaning tank can flow into the cylinder through the through hole. When the cleaning cylinder moves up and down, it will drive the guide plate to slide in the limiting groove. The guide plate and the limiting groove cooperate to guide the cleaning cylinder and make the cleaning cylinder move smoothly.

[0018] Preferably, the rotating shaft has a ring array of vibration grooves inside, a limit frame is fixedly installed inside the vibration groove, a sliding plate passes through the limit frame, a striking block is fixedly connected to one end of the sliding plate and the striking block is located on the side of the limit frame, a reset spring is fixedly installed inside the vibration groove and the other end of the reset spring is fixedly connected to the side of the striking block, and one end of the sliding plate is arc-shaped.

[0019] By adopting the above scheme, after the reagent needle is immersed in the cleaning reagent in the cylinder, the position of the drive block is adjusted so that the drive block moves to the predetermined position. When the rotating shaft rotates, it will limit one end of the sliding plate. When the sliding plate contacts the rotating shaft, the drive block will apply pressure to one end of the sliding plate, causing the sliding plate to slide into the vibration groove. The reset spring drives the knocking block to reset and collide with the limit frame. The vibration groove will cause the rotating shaft to vibrate, and the vibration will be transmitted to the cylinder through the rotating shaft. In turn, the cleaning reagent inside the cylinder will vibrate. When the reagent vibrates, it will come into contact with the reagent needle, which will further clean the reagent needle and ensure the cleanliness of the reagent needle.

[0020] Preferably, a movable groove is fixedly provided inside the ring frame, a load-bearing block is inserted through the movable groove, a driving block is fixedly provided on the side of the load-bearing block, and one end of the driving block is arc-shaped. An electric push rod is fixedly provided inside the movable groove, and the telescopic end of the electric push rod is fixedly connected to the side of the load-bearing block. A guide shaft is fixedly provided inside the movable groove, and the guide shaft passes through the inside of the load-bearing block.

[0021] By adopting the above scheme, the position of the load-bearing block is adjusted by the operation of the electric push rod, and the load-bearing block is guided by the guide shaft, so that the load-bearing block moves smoothly. When the load-bearing block moves, it will drive the drive block to move smoothly.

[0022] Preferably, the power mechanism includes a dual-output shaft motor, a reducer, and a drive gear. The dual-output shaft motor is fixed in the groove, the reducer is fixed inside the protective box, and the output end of the dual-output shaft motor is fixedly connected to the input end of the reducer. The output end of the reducer is fixedly connected to the center position of the drive gear, and the drive gear meshes with the transmission gear.

[0023] By adopting the above scheme, when the dual-output shaft motor is working, it will drive the reducer and the fan to work. The reducer will drive the drive gear to rotate. When the drive gear rotates, it will cause the rotating shaft to rotate through the transmission gear.

[0024] Preferably, the wind power component includes a square frame, a fan, a filter plate, and a delivery pipe. The square frame is fixed inside the groove, the fan is fixed inside the square frame, and the other output end of the dual-shaft motor is connected to the impeller inside the fan. The filter plate is fixed to the side of the square frame, one end of the delivery pipe is connected to the output end of the fan, and a nozzle is provided inside the hole, and the delivery pipe is connected to the nozzle.

[0025] By adopting the above scheme, when the fan is working, it will draw and deliver compressed air, which will generate airflow. The airflow will enter the nozzle through the delivery pipe, and then the airflow will be directed to the reagent needle for cleaning.

[0026] Compared with the prior art, the beneficial effects of the present invention are: 1. The present invention discloses a cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer. By setting up a cleaning cylinder, it can perform all-round cleaning of reagent needles, effectively improving the cleaning effect. The reagent needle is placed on one side of the spray nozzle. The pump is started to draw cleaning reagent from inside the cleaning tank. The cleaning reagent flows into the infusion tube through a rotary joint. The infusion tube is connected to the distribution tank, allowing the cleaning reagent to flow smoothly into the distribution tank. Then, it is sprayed directionally onto the surface of the reagent needle through the spray nozzle, completing the rinsing and cleaning operation. Simultaneously, the dual-shaft motor drives the reducer and fan to work synchronously. The reducer drives the drive gear to rotate. The drive gear, through the meshing of the transmission gear, drives the rotating shaft to rotate. Then, through the sequential transmission of each group of adjacent transmission gears, it drives the other rotating shafts to rotate synchronously. Through the connecting assembly, it drives the corresponding cylinder and the cleaning cylinder to rotate as a whole, thereby causing the spray nozzle to rotate with the structure, achieving 360° circumferential cleaning of the reagent needle and ensuring an all-round cleaning effect.

[0027] 2. The cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer described in this invention utilizes the cooperation of a rotating shaft and a vibration groove to cause the cleaning reagent to vibrate, thus performing vibration cleaning on the reagent needle and further improving the cleaning effect. The reagent needle can be immersed in the cleaning reagent during downward movement, achieving immersion cleaning. After the reagent needle is immersed in the cleaning reagent in the cylinder, the drive block is adjusted to a preset position. When the rotating shaft rotates, it limits the end of the sliding plate. Simultaneously, the drive block applies pressure to the end of the sliding plate, pushing it into the vibration groove. A reset spring drives the striking block to reset and collide with the limiting frame. The vibration groove drives the rotating shaft to vibrate, and the vibration is transmitted to the inside of the cylinder, causing the cleaning reagent inside to oscillate. The oscillating cleaning reagent fully contacts the reagent needle, thereby achieving a deep secondary cleaning treatment of the reagent needle.

[0028] 3. The cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer described in this invention, by setting up a fan and a nozzle, enables the air-drying and cleaning of reagent needles. When the fan is working, it draws compressed air to form an airflow, which is introduced into the nozzle through a delivery pipe and then blown directionally onto the reagent needle. After the reagent needle is cleaned, it moves upward slowly. When it passes through the airflow area of ​​the nozzle, the airflow can thoroughly clean and dry the reagent needle, completing the cleaning process. Attached Figure Description

[0029] Figure 1 This is a schematic diagram of the main structure of the cleaning auxiliary structure for the sequencing chip platform based on a gene sequencer according to the present invention; Figure 2 This is a schematic diagram of the cleaning tank structure of the present invention; Figure 3 This is a three-dimensional structural diagram of the load-bearing plate, guide cylinder, and guide rod of the present invention; Figure 4This is a three-dimensional structural diagram of the cylindrical and cleaning cylinders of the present invention; Figure 5 This is a three-dimensional structural diagram of the protective box of the present invention; Figure 6 This is a three-dimensional structural diagram of the infusion tube and rotary joint of the present invention; Figure 7 This is a three-dimensional structural diagram of the rotating shaft of the present invention; Figure 8 This is a schematic diagram of the three-dimensional structure of the protective box and groove of the present invention; Figure 9 This is a schematic diagram of the ring frame structure of the present invention; Figure 10 For the present invention Figure 9 Enlarged structural diagram of A in the middle; Figure 11 This is a schematic diagram of the three-dimensional structure of the square frame of the present invention; Figure 12 This is a three-dimensional structural diagram of the drive spring and guide cylinder of the present invention.

[0030] In the diagram: 1. Load-bearing plate; 2. Cleaning tank; 3. Support plate; 4. Hole; 5. Guide cylinder; 6. Guide rod; 7. Protective box; 8. Load-bearing frame; 9. Rotating shaft; 10. Nozzle; 11. Infusion tube; 12. Rotary joint; 13. Positioning bolt; 14. Annular groove; 15. Transmission gear; 16. Frame; 17. Pump; 18. Cylinder; 19. Threaded hole; 20. Through hole; 21. Cleaning cylinder; 22. Limiting groove; 23. Guide plate; 24. Ring; 2 5. Diversion channel; 26. Spray nozzle; 27. Drain head; 28. Circular frame; 29. ​​Vibration channel; 30. Limiting frame; 31. Sliding plate; 32. Striking block; 33. Return spring; 34. Movable groove; 35. Electric push rod; 36. Guide shaft; 37. Load-bearing block; 38. Drive block; 39. Groove; 40. Dual-shaft motor; 41. Reducer; 42. Drive gear; 43. Square frame; 44. Fan; 45. Filter plate; 46. Conveying pipe; 47. Drive spring. Detailed Implementation

[0031] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0032] Please see Figure 1-12This invention provides a technical solution: a cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer, including a load-bearing plate 1, a cleaning tank 2 fixedly disposed on the top of the load-bearing plate 1, a support plate 3 disposed inside the cleaning tank 2, a plurality of holes 4 corresponding to the reagent needles to be cleaned disposed on the support plate 3, a guide component for guiding the support plate 3 disposed on the load-bearing plate 1, a cylinder 18 corresponding to the holes 4 disposed inside the cleaning tank 2, a cleaning cylinder 21 passing through the cylinder 18, a diversion groove 25 embedded inside the cleaning cylinder 21, a spray hole 26 disposed on the diversion groove 25, a protective box 7 fixedly disposed on the bottom of the load-bearing plate 1, a rotating mechanism for driving the cylinder 18 to rotate disposed inside the protective box 7, a groove 39 disposed at the bottom of the protective box 7, a power mechanism disposed inside the groove 39, a drain head 27 disposed on the side of the cleaning tank 2, and a wind component disposed inside the groove 39; An external controller for the cleaning auxiliary structure of the sequencing chip platform based on a gene sequencer can control the operation of the cleaning auxiliary structure. After the cleaning tank 2 is fixed in the cleaning position by the support plate 1, the cleaning tank 2 contains cleaning reagent. During the testing of the sequencing chip platform based on the gene sequencer, the reagent needle needs to draw the sample to the sequencing station for detection. However, after the detection is completed, when it is necessary to clean the reagent needle, the position of the reagent needle is moved so that the reagent needle is aligned with the corresponding hole 4. After the reagent needle moves down and passes through the hole 4 into the cleaning tank 2, it will insert into the cleaning cylinder 21 and be located on one side of the spray hole 26. The pump 17 is controlled to work to extract the cleaning reagent inside the cleaning tank 2. The extracted cleaning reagent flows into the diversion tank. After entering the 25, the cleaning solution is sprayed onto the reagent needle through the nozzle 26, which can rinse and clean the reagent needle. At the same time, the power mechanism drives the rotating mechanism to move, which can drive the cylinder 18 and the cleaning cylinder 21 to rotate, which in turn drives the nozzle 26 to rotate, thus cleaning the reagent needle 360 ​​degrees, ensuring the cleaning effect. When the reagent needle continues to move downward, it will apply pressure to the support plate 3, causing the support plate 3 to move downward. When the support plate 3 moves downward, it will be guided by the guide component to move the support plate 3 smoothly. At the same time, when the support plate 3 moves, it will apply pressure to the cleaning cylinder 21, causing the cleaning cylinder 21 to move downward. The cleaning reagent inside the cleaning tank 2 will flow into the cylinder 18 through the through hole 20, and the reagent needle can be immersed in the reagent for cleaning. Furthermore, when the power mechanism moves, it will drive the wind component to move and generate wind. The wind flows into the nozzle 10 and will cause the wind to flow towards the reagent needle. After the reagent needle is cleaned, it can move upward slowly. When the reagent needle moves past the nozzle 10, the wind will dry and clean the reagent needle.

[0033] Furthermore, the guiding assembly includes a guide cylinder 5 and a guide rod 6. The guide cylinder 5 is symmetrically fixed inside the cleaning tank 2, and the guide rod 6 passes through the guide cylinder 5. The top end of the guide rod 6 is fixedly connected to the support plate 3. A drive spring 47 is fixedly installed inside the guide cylinder 5, and one end of the drive spring 47 is fixedly connected to the end of the guide rod 6. When the support plate 3 moves, it will cause the guide rod 6 to slide inside the guide cylinder 5. Through the cooperation of the guide rod 6 and the guide cylinder 5, the support plate 3 will be guided, so that the support plate 3 moves smoothly. When the guide rod 6 moves down, it will put pressure on the drive spring 47 and compress the drive spring 47. When the pressure on the support plate 3 is no longer applied, the drive spring 47 will reset and push the guide rod 6 to move up and reset.

[0034] Furthermore, the rotating mechanism includes a load-bearing frame 8, a rotating shaft 9, a transmission gear 15, an annular frame 28, and a connecting assembly. The load-bearing frame 8 is fixed inside the protective box 7. The annular frame 28 corresponding to the cylinder 18 is fixed on the load-bearing frame 8. The rotating shaft 9 is rotatably disposed inside the annular frame 28. The transmission gear 15 is fixed on the rotating shaft 9, and adjacent transmission gears 15 mesh with each other. The connecting assembly for connecting the cylinder 18 and the rotating shaft 9 is disposed on the rotating shaft 9. The rotating shaft 9 can be fixedly connected to the cylinder 18 by the connecting component. The rotating shaft 9 is supported by the cooperation of the load-bearing frame 8 and the ring frame 28. The rotating shaft 9 is engaged with the ring frame 28, which allows the rotating shaft 9 to rotate smoothly inside the ring frame 28. When the rotating shaft 9 rotates, it drives the transmission gear 15 to rotate. When the transmission gear 15 rotates, it can drive the adjacent rotating shaft 9 to rotate through the cooperation of the adjacent transmission gear 15, and then drive the corresponding cylinder 18 to rotate through the connecting assembly.

[0035] Furthermore, the connecting assembly includes a positioning bolt 13, an annular groove 14, and a threaded hole 19. The annular groove 14 is disposed on the top of the rotating shaft 9, the positioning bolt 13 is disposed inside the rotating shaft 9, and the threaded hole 19 is disposed on the cylinder 18, and the positioning bolt 13 is threadedly connected to the threaded hole 19. After the bottom end of the cylinder 18 enters the annular groove 14, and the threaded hole 19 is aligned with the positioning bolt 13, the positioning bolt 13 is rotated to connect with the threaded hole 19, which will position the cylinder 18.

[0036] Furthermore, an infusion tube 11 is inserted through the rotating shaft 9, and a rotary joint 12 is connected to the bottom end of the infusion tube 11. A frame 16 is fixedly installed on the side of the cleaning tank 2. A pumping pump 17 is installed inside the frame 16, and the input end of the pumping pump 17 is connected to the inside of the cleaning tank 2. The output end of the pumping pump 17 is connected to the rotary joint 12 through a pipe. When the pump 17 operates, it draws out the cleaning reagent. Through the rotary joint 12, the reagent flows into the infusion tube 11. The infusion tube 11 is connected to the diversion tank 25 through a pipe, and the cleaning reagent flows into the diversion tank 25.

[0037] Furthermore, the cylinder 18 is provided with through holes 20 in an array, the cylinder 18 is provided with a limiting groove 22, a guide plate 23 is provided inside the limiting groove 22, and the guide plate 23 is fixedly connected to the side of the cleaning cylinder 21. The top of the cleaning cylinder 21 is provided with a ring 24. The cleaning reagent inside the cleaning tank 2 can flow into the cylinder 18 through the through hole 20. When the cleaning cylinder 21 moves up and down, it will drive the guide plate 23 to slide in the limiting groove 22. The guide plate 23 and the limiting groove 22 cooperate to guide the cleaning cylinder 21, so that the cleaning cylinder 21 moves smoothly.

[0038] Furthermore, the rotating shaft 9 is provided with a ring array of vibration grooves 29, and a limit frame 30 is fixedly installed inside the vibration groove 29. A sliding plate 31 is inserted inside the limit frame 30. A striking block 32 is fixedly connected to one end of the sliding plate 31 and is located on the side of the limit frame 30. A return spring 33 is fixedly installed inside the vibration groove 29 and the other end of the return spring 33 is fixedly connected to the side of the striking block 32. One end of the sliding plate 31 is arc-shaped. After the reagent needle is immersed in the cleaning reagent inside the cylinder 18, the position of the drive block 38 is adjusted so that the drive block 38 moves to a predetermined position. When the rotating shaft 9 rotates, it will limit one end of the sliding plate 31. When the sliding plate 31 contacts the rotating shaft 9, the drive block 38 will apply pressure to one end of the sliding plate 31, causing the sliding plate 31 to slide into the vibration groove 29. The reset spring 33 drives the striking block 32 to reset and collide with the limit frame 30. The vibration groove 29 will cause the rotating shaft 9 to vibrate, and the vibration will be transmitted to the cylinder 18 through the rotating shaft 9. This will cause the cleaning reagent inside the cylinder 18 to vibrate. When the reagent vibrates, it will contact the reagent needle, which will further clean the reagent needle and ensure the cleanliness of the reagent needle.

[0039] Furthermore, a movable groove 34 is fixedly provided inside the ring frame 28, a load-bearing block 37 is inserted inside the movable groove 34, a drive block 38 is fixedly provided on the side of the load-bearing block 37, and one end of the drive block 38 is arc-shaped. An electric push rod 35 is fixedly provided inside the movable groove 34, and the telescopic end of the electric push rod 35 is fixedly connected to the side of the load-bearing block 37. A guide shaft 36 is fixedly provided inside the movable groove 34, and the guide shaft 36 passes through the inside of the load-bearing block 37. The position of the load-bearing block 37 is adjusted by the operation of the electric push rod 35, and the load-bearing block 37 is guided by the guide shaft 36, so that the load-bearing block 37 moves smoothly. When the load-bearing block 37 moves, it will drive the drive block 38 to move smoothly.

[0040] Furthermore, the power mechanism includes a dual-output shaft motor 40, a reducer 41, and a drive gear 42. The dual-output shaft motor 40 is fixed in the groove 39, the reducer 41 is fixed inside the protective box 7, and the output end of the dual-output shaft motor 40 is fixedly connected to the input end of the reducer 41. The output end of the reducer 41 is fixedly connected to the center position of the drive gear 42, and the drive gear 42 meshes with the transmission gear 15. When the dual-output shaft motor 40 is working, it will drive the reducer 41 and the fan 44 to work. The reducer 41 will drive the drive gear 42 to rotate. When the drive gear 42 rotates, it will cause the rotating shaft 9 to rotate through the transmission gear 15.

[0041] Furthermore, the wind power assembly includes a square frame 43, a fan 44, a filter plate 45, and a delivery pipe 46. The square frame 43 is fixed inside the groove 39, the fan 44 is fixed inside the square frame 43, and the other output end of the dual-shaft motor 40 is connected to the impeller inside the fan 44. The filter plate 45 is fixed to the side of the square frame 43, one end of the delivery pipe 46 is connected to the output end of the fan 44, and a nozzle 10 is provided inside the hole 4, and the delivery pipe 46 is connected to the nozzle 10. When the drive fan 44 is working, it draws and delivers compressed air, which in turn generates airflow. The airflow passes through the delivery pipe 46 and enters the nozzle 10. The airflow through the nozzle 10 is directed to the reagent needle for cleaning. The delivery pipe 46 is retractable.

[0042] Integrating multiple cleaning technologies such as directional jet cleaning, rotary spraying, immersion cleaning, vibration-assisted cleaning, and wind-driven drying, this system achieves synergistic effects through time-series coordination, functional complementarity, power reuse, and structural linkage. Sharing a single power system and triggering actions through structural linkage significantly improves cleaning thoroughness and efficiency, effectively solving the problems of incomplete cleaning and residue buildup associated with single technologies. It is suitable for the high-cleanliness and high-precision operating conditions of gene sequencing chip platforms. Working principle: First, after fixing the cleaning tank 2 in the cleaning position, the cleaning tank 2 contains cleaning reagent. When cleaning the reagent needle, the position of the reagent needle is moved so that the reagent needle is aligned with the corresponding hole 4. After the reagent needle moves down and passes through the hole 4 into the cleaning tank 2, it will insert into the cleaning cylinder 21 and be positioned on one side of the spray hole 26. The pump 17 is controlled to extract the cleaning reagent inside the cleaning tank 2. The extraction of cleaning reagent is coordinated with the rotary joint 12, which will cause the reagent to flow into the infusion tube 11. The infusion tube 11 is connected to the diversion tank 25 through a pipe, and then the cleaning reagent will flow into the diversion tank 25. Through the spray hole 26, the cleaning liquid will be sprayed onto the reagent needle, which can clean the reagent needle. During the rinsing and cleaning process, the dual-shaft motor 40 drives the reducer 41 and fan 44. The reducer 41 drives the drive gear 42, which in turn rotates the rotating shaft 9 via the transmission gear 15. The rotating shaft 9 then drives the transmission gear 15, which in turn drives the adjacent rotating shaft 9 via the adjacent transmission gear 15. This, in turn, drives the corresponding cylinder 18 and cleaning cylinder 21 to rotate via the connecting assembly, which in turn drives the nozzle 26 to rotate. This allows for a 360-degree cleaning of the reagent needle, ensuring a thorough cleaning effect. As the reagent needle continues to move downwards, pressure is applied to the support plate 3, causing it to move downwards. When the support plate 3 moves downward, the guide rod 6 and guide cylinder 5 cooperate to guide the support plate 3, allowing it to move smoothly. As the support plate 3 moves, it applies pressure to the cleaning cylinder 21, causing it to move downward. The cleaning reagent inside the cleaning tank 2 flows into the cylinder 18 through the through hole 20. The reagent needle moves downward and enters the reagent for immersion cleaning. After the reagent needle is immersed in the cleaning reagent in the cylinder 18, the position of the drive block 38 is adjusted. After the drive block 38 moves to a predetermined position, it limits one end of the sliding plate 31 when the rotating shaft 9 rotates. When the sliding plate 31 contacts the rotating shaft 9, the drive block 38 applies pressure to one end of the sliding plate 31, causing it to slide into the vibration tank 29. The reset spring 33 drives the knocking block 32 to reset and collide with the limit frame 30. The vibration groove 29 causes the rotating shaft 9 to vibrate, and the vibration is transmitted to the cylinder 18 through the rotating shaft 9. This causes the cleaning reagent inside the cylinder 18 to vibrate. When the reagent vibrates, it comes into contact with the reagent needle, which further cleans the reagent needle and ensures the cleanliness of the reagent needle. When the drive fan 44 is working, it draws and delivers compressed air, which generates airflow. The airflow enters the nozzle 10 through the delivery pipe 46 and flows to the reagent needle through the nozzle 10. After the reagent needle is cleaned, it can move slowly upward. When the reagent needle moves past the nozzle 10, the airflow dries and cleans the reagent needle.

[0043] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed invention.

Claims

1. A cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer, characterized in that: The system includes a load-bearing plate (1), a cleaning tank (2) fixedly mounted on the top of the load-bearing plate (1), a support plate (3) inside the cleaning tank (2), a plurality of holes (4) corresponding to the reagent needles to be cleaned on the support plate (3), a guide assembly for guiding the support plate (3) on the load-bearing plate (1), a cylinder (18) corresponding to the holes (4) inside the cleaning tank (2), and a cleaning cylinder (21) passing through the cylinder (18). The cylinder (21) is inlaid with a diversion groove (25), and the diversion groove (25) is provided with a spray hole (26). The bottom of the load-bearing plate (1) is fixedly provided with a protective box (7). The protective box (7) is provided with a rotating mechanism for driving the cylinder (18) to rotate. The bottom of the protective box (7) is provided with a groove (39). The groove (39) is provided with a power mechanism. The cleaning tank (2) is provided with a drain head (27) on the side. The groove (39) is provided with a wind power component. The rotating mechanism includes a load-bearing frame (8), a rotating shaft (9), a transmission gear (15), an annular frame (28), and a connecting assembly. The load-bearing frame (8) is fixed inside the protective box (7), and the annular frame (28) corresponding to the cylinder (18) is fixed on the load-bearing frame (8). The rotating shaft (9) is rotatably arranged inside the annular frame (28). The transmission gear (15) is fixed on the rotating shaft (9), and adjacent transmission gears (15) mesh with each other. The connecting assembly for connecting the cylinder (18) and the rotating shaft (9) is arranged on the rotating shaft (9). The cylinder (18) is provided with an array of through holes (20), and the cylinder (18) is provided with a limiting groove (22). A guide plate (23) is provided inside the limiting groove (22), and the guide plate (23) is fixedly connected to the side of the cleaning cylinder (21). A ring (24) is provided at the top of the cleaning cylinder (21). The rotating shaft (9) is provided with a ring array of vibration grooves (29). A limit frame (30) is fixedly installed in the vibration groove (29). A sliding plate (31) is passed through the limit frame (30). A striking block (32) is fixedly connected to one end of the sliding plate (31), and the striking block (32) is located on the side of the limit frame (30). A return spring (33) is fixedly installed in the vibration groove (29), and the other end of the return spring (33) is fixedly connected to the side of the striking block (32). One end of the sliding plate (31) is arc-shaped. The ring frame (28) is fixedly provided with a movable groove (34), and a load-bearing block (37) is provided inside the movable groove (34). A drive block (38) is fixedly provided on the side of the load-bearing block (37), and one end of the drive block (38) is arc-shaped. An electric push rod (35) is fixedly provided inside the movable groove (34), and the telescopic end of the electric push rod (35) is fixedly connected to the side of the load-bearing block (37). A guide shaft (36) is fixedly provided inside the movable groove (34), and the guide shaft (36) passes through the inside of the load-bearing block (37).

2. The cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer according to claim 1, characterized in that: The guiding assembly includes a guide cylinder (5) and a guide rod (6). The guide cylinder (5) is symmetrically fixed inside the cleaning tank (2). The guide rod (6) passes through the guide cylinder (5) and the top end of the guide rod (6) is fixedly connected to the support plate (3). A drive spring (47) is fixedly installed inside the guide cylinder (5) and one end of the drive spring (47) is fixedly connected to the end of the guide rod (6).

3. The cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer according to claim 2, characterized in that: The connecting assembly includes a positioning bolt (13), an annular groove (14) and a threaded hole (19). The annular groove (14) is located on the top of the rotating shaft (9), the positioning bolt (13) is located inside the rotating shaft (9), and the threaded hole (19) is located on the cylinder (18). The positioning bolt (13) is threadedly connected to the threaded hole (19).

4. The cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer according to claim 3, characterized in that: An infusion tube (11) is inserted inside the rotating shaft (9), and a rotary joint (12) is connected to the bottom end of the infusion tube (11). A frame (16) is fixedly installed on the side of the cleaning tank (2), and a pump (17) is installed inside the frame (16). The input end of the pump (17) is connected to the inside of the cleaning tank (2), and the output end of the pump (17) is connected to the rotary joint (12) through a pipe.

5. The cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer according to claim 1, characterized in that: The power mechanism includes a dual-output shaft motor (40), a reducer (41), and a drive gear (42). The dual-output shaft motor (40) is fixed in the groove (39), the reducer (41) is fixed inside the protective box (7), and the output end of the dual-output shaft motor (40) is fixedly connected to the input end of the reducer (41). The output end of the reducer (41) is fixedly connected to the center position of the drive gear (42), and the drive gear (42) meshes with the transmission gear (15).

6. The cleaning auxiliary structure for a sequencing chip platform based on a gene sequencer according to claim 5, characterized in that: The wind power assembly includes a square frame (43), a fan (44), a filter plate (45), and a delivery pipe (46). The square frame (43) is fixed inside the groove (39). The fan (44) is fixed inside the square frame (43), and the other output end of the dual-shaft motor (40) is connected to the impeller inside the fan (44) via a drive. The filter plate (45) is fixed on the side of the square frame (43). One end of the delivery pipe (46) is connected to the output end of the fan (44). A nozzle (10) is provided inside the hole (4), and the delivery pipe (46) is connected to the nozzle (10).

Images