Method for evaluating inflammation after delivery

CN122459686APending Publication Date: 2026-07-24AJINOMOTO CO INC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
AJINOMOTO CO INC
Filing Date
2024-12-25
Publication Date
2026-07-24

AI Technical Summary

Technical Problem

The lack of reliable methods in the current technology for pre-diagnosing the risk of postpartum inflammation before delivery makes it impossible to effectively prevent and reduce the occurrence of postpartum inflammation.

Method used

By measuring the concentrations of 25 amino acids, 37 biochemical indicators, and 4 test items in the blood of ruminants before parturition, and using mathematical formulas to calculate the inflammatory status after parturition, a reliable method and device for assessing inflammatory risk is provided.

Benefits of technology

It enables the provision of reliable information on inflammatory status before parturition, helping dairy farmers reduce postpartum inflammation and improve production efficiency through preventative nutritional interventions.

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Abstract

The present application provides an evaluation method that can provide reliable information related to the state of inflammation after delivery before delivery. In the present embodiment, the concentration values of 25 amino acids (Ala, Arg, Asn, Asp, BCAA, Cit, Cys, Glu, Gin, Gly, His, Ile, Leu, Lys, Met, 3MeHis, Orn, Phe, Pro, Ser, Tau, Thr, Trp, Tyr, Val) in the blood of a ruminant before delivery, the test values of 37 biochemicals (ALB, ALT, AST, BHBA, BUN, Ca, gGTP, Glc, Glob, NEFA, T-Bil, TCHO, TG, TP, P, Na, K, Cl, GGT, ALP, LDH, CPK, LDL-C, HDL-C, Mg, AMY, PA, LA, CRE, LBP, IL-1β, haptoglobin, serum amyloid A, IL-6, TNF-α, Cortisol, kynurenine) in the blood, and at least one of the measurement values of 4 measurement items (d- ROMs value, BAP value, BAP value / d- ROMs value, d- ROMs value / BAP value) obtained from the blood are used to evaluate the state of inflammation after delivery of the ruminant.
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Citation Information

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