Marker pushing instrument and tissue marker device

Abstract

This application discloses a marker delivery device and a tissue marking device, relating to the field of medical device technology. The marker delivery device includes: a slender cannula with an outlet connecting its interior and exterior; the interior of the slender cannula is used to house a marker; the slender cannula is inserted into a biopsy needle, and the outlet faces the sampling window of the biopsy needle; and a support sleeve with a fitting hole having an opening penetrating the side wall of the support sleeve. At least a portion of the slender cannula is fitted into the fitting hole through the opening, and the outlet faces the opening, allowing the marker to enter the target tissue through the outlet, the opening, and the sampling window. The outer wall of the slender cannula and the outer wall of the support sleeve are approximately tangent at the opening. The technical solution provided by this application reduces the movement of the marker delivery device within the biopsy needle and lowers the risk of the marker getting stuck between the outlet and the sampling window.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and in particular to a marker delivery device and a tissue marking device. Background Technology

[0002] Traditional marker delivery devices typically involve the user holding the handle, inserting a needle into the target tissue, and pushing a plunger inside the needle to move the marker into the target tissue, thus implanting the marker around the lesion for quick location of the lesion via imaging. However, when used in biopsy procedures, this method requires first using a biopsy needle to obtain a sample, then removing the needle from the target tissue, and finally re-inserting the marker into the vicinity of the biopsy site using the marker delivery device. This can cause secondary puncture injuries to the patient.

[0003] In related technologies, a marker delivery device adapted to a biopsy needle is designed. After the biopsy needle is used to extract a sample, it is not removed from the target tissue. Instead, a thin, long cannula containing the marker is inserted into the sampling channel inside the biopsy needle. The marker is then implanted into the biopsy sampling point through the sampling window of the biopsy needle from the outlet of the thin cannula, thus avoiding secondary harm to the patient.

[0004] However, the outer diameter of the slender cannula containing the marker is usually small, which makes it easy for it to move around inside the biopsy needle. This makes it difficult to align the outlet of the slender cannula with the sampling window, and the marker can easily get stuck between the outlet and the sampling window. Summary of the Invention

[0005] The main objective of this application is to provide a marker delivery device and a tissue marking apparatus, which aim to solve at least one of the aforementioned technical problems.

[0006] To achieve the above objectives, the marker delivery device proposed in this application includes:

[0007] A long, thin cannula has an exit port connecting its interior and exterior. The interior of the cannula is used to house a marker. The cannula is inserted into a biopsy needle, and the exit port faces the sampling window of the biopsy needle.

[0008] The support sleeve has a fitting hole with an opening that penetrates the side wall of the support sleeve. At least a portion of the slender cannula is fitted into the fitting hole through the opening, and the outlet faces the opening, so that the marker can enter the target tissue through the outlet, the opening, and the sampling window.

[0009] The outer wall of the slender insertion tube is approximately tangent to the outer wall of the support sleeve at the opening.

[0010] In one embodiment, the front end of the elongated cannula is completely housed within the sleeve hole, and the minimum distance between the outer wall of the elongated cannula and the outer wall of the support sleeve along the radial direction of the elongated cannula is less than or equal to 0.5 mm.

[0011] In one embodiment, a portion of the outer wall of the front end of the elongated cannula protrudes from the opening beyond the outer wall of the support sleeve, and the maximum distance between the elongated cannula protruding beyond the outer wall of the support sleeve and the outer wall of the support sleeve along the radial direction of the elongated cannula is less than or equal to 0.5 mm.

[0012] In one embodiment, the marker delivery device further includes a plug, and the front end of the slender cannula has a notch that penetrates the inside and outside of the slender cannula. The plug seals the front end of the slender cannula and together with the inner wall of the notch, forms the outlet.

[0013] In one embodiment, the plug and the support sleeve are an integral structure; and / or,

[0014] The outer diameter of the end of the plug away from the slender cannula decreases in the direction away from the slender cannula.

[0015] In one embodiment, the inner wall of the fitting hole is provided with a receiving groove, and a gel structure is provided in the receiving groove, the gel structure connecting the inner wall of the receiving groove and the outer wall of the slender insertion tube.

[0016] In one embodiment, the receiving groove extends along the axial direction of the fitting hole; and / or,

[0017] The receiving groove extends along the circumferential direction of the fitting hole.

[0018] In one embodiment, the marker delivery device further includes a pusher, the front end of which is axially slidably inserted into the elongated cannula, and the rear end of which extends outside the elongated cannula to drive the marker to slide toward the outlet.

[0019] In one embodiment, the marker delivery device further includes a gripping structure comprising two first handles disposed opposite each other on both sides of the rear end of the elongated cannula.

[0020] This application also proposes a tissue marking device, comprising:

[0021] Markers; and

[0022] The aforementioned marker delivery device is used to transfer the marker into the target tissue.

[0023] In one embodiment, the marker is made of shape memory metal. The marker unfolds into a long strip inside the elongated cannula and extends along the elongated cannula. When the marker leaves the elongated cannula, the marker at least partially returns to its original bending shape to form a curved structure.

[0024] The technical solution of this application increases the overall outer diameter of the front end of the marker delivery device by adding a support sleeve to the outside of the slender cannula, reducing the dimensional difference between the front end and the inner diameter of the biopsy needle's inner tube. This reduces the movement of the marker delivery device within the biopsy needle, making it easier to align the outlet with the sampling window and reducing the risk of the marker getting stuck between the outlet and the sampling window. Furthermore, it improves the stability when moving the marker, reducing discomfort to the patient. Further, the outer wall of the slender cannula and the outer wall of the support sleeve are approximately tangent at the opening, allowing the outlet on the slender cannula to be located on or near the outer circumference of the support sleeve. When the marker delivery device is inserted into the biopsy needle with the outlet facing the sampling window, the outlet on the slender cannula is more easily brought closer to the sampling window, reducing the distance between them and further lowering the risk of the marker getting stuck between them, ensuring the marker can be successfully implanted into the target tissue through the sampling window. In addition, the fitting hole has an opening located on the side wall of the support sleeve. When the delivery tube is assembled with the support sleeve, the delivery tube can be inserted into the fitting hole radially along the support sleeve through this opening, rather than being inserted into the fitting hole axially from the end of the support sleeve. This reduces the relative displacement distance between the support sleeve and the delivery tube during the assembly process, which reduces the processing accuracy requirements of the support sleeve and the delivery tube, reduces the manufacturing and assembly difficulty, and also reduces the powder falling off due to friction during the assembly process. This reduces the risk of powder entering the implanted tissue and reduces the adverse effects of the marker implantation surgery. Attached Figure Description

[0025] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.

[0026] Figure 1 A schematic diagram of the structure of an embodiment of the marker delivery device provided in this application;

[0027] Figure 2 A partial structural diagram of an embodiment of the marker delivery device provided in this application Figure 1 ;

[0028] Figure 3 for Figure 2 Sectional view at point AA;

[0029] Figure 4 A schematic diagram of the biopsy needle inserted into the marker delivery device provided in this application;

[0030] Figure 5 A partial structural diagram of the marker delivery device and biopsy needle provided in this application;

[0031] Figure 6 Cross-sectional view of a portion of the structure of the marker delivery device and biopsy needle provided in this application. Figure 1 ;

[0032] Figure 7 A schematic diagram of the support sleeve and plug of the marker pushing device provided in this application;

[0033] Figure 8 for Figure 7 Sectional view at point BB;

[0034] Figure 9 A cross-sectional view of the support sleeve and plug of the marker pushing device provided in this application;

[0035] Figure 10 A cross-sectional view of the support sleeve, plug, and part of the elongated cannula of an embodiment of the marker delivery device provided in this application;

[0036] Figure 11 Cross-sectional view of a portion of the structure of the marker delivery device and biopsy needle provided in this application. Figure 2 ;

[0037] Figure 12 A partial structural diagram of an embodiment of the marker delivery device provided in this application Figure 2 ;

[0038] Figure 13 A cross-sectional view of a partial structure of an embodiment of the marker delivery device provided in this application;

[0039] Figure 14 A cross-sectional view of the support sleeve and elongated cannula of another embodiment of the marker delivery device provided in this application.

[0040] Explanation of icon numbers:

[0041] 10. Markers;

[0042] 20. Biopsy needle; 21. Outer blade; 22. Inner blade; 23. Sampling window;

[0043] 100. Slender insertion cannula; 101. Outlet; 102. Notch;

[0044] 210. Support sleeve; 211. Fitting hole; 212. Opening; 213. Receiving groove; 220. Plug;

[0045] 300. Pushing component; 310. Pushing pin part; 320. Force application part;

[0046] 400. Grip structure; 410. Sleeve section; 420. First handle;

[0047] 500, Limiting component; 510, Sleeve; 511, Notch; 520, Second handle;

[0048] 600. Elastic components.

[0049] The realization of the purpose, functional features and advantages of this application will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation

[0050] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of the embodiments. Based on the embodiments of this application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of this application.

[0051] It should be noted that if the embodiments of this application involve directional indicators (such as up, down, left, right, front, back, etc.), the directional indicators are only used to explain the relative positional relationship and movement of the components in a specific posture. If the specific posture changes, the directional indicators will also change accordingly.

[0052] In this application, unless otherwise expressly specified and limited, the terms "connection" and "fixed" should be interpreted broadly. For example, "fixed" can mean a fixed connection, a detachable connection, or an integral part; "connection" can mean a mechanical connection or an electrical connection, a direct connection or an indirect connection through an intermediate medium, or a connection within two components or an interaction between two components. Unless otherwise expressly limited, those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0053] Furthermore, if the embodiments of this application involve descriptions such as "first" or "second," these descriptions are for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined with "first" or "second" may explicitly or implicitly include at least one of those features. Additionally, the meaning of "and / or" throughout the text includes three parallel solutions. Taking "A and / or B" as an example, it includes solution A, solution B, or a solution where both A and B are satisfied simultaneously. Furthermore, the technical solutions of the various embodiments can be combined with each other, but this must be based on the ability of those skilled in the art to implement them. When the combination of technical solutions is contradictory or impossible to implement, it should be considered that such a combination of technical solutions does not exist and is not within the scope of protection claimed in this application.

[0054] This application proposes a marker delivery device.

[0055] Please see Figures 1 to 6 as well as Figure 8 , Figure 1 This is a schematic diagram of the structure of an embodiment of the marker delivery device provided in this application. Figure 2 A partial structural diagram of an embodiment of the marker delivery device provided in this application Figure 1 , Figure 3 for Figure 2 Sectional view at point AA. Figure 4 This is a schematic diagram of the marker delivery device provided in this application penetrating the biopsy needle. Figure 5 This is a partial structural diagram of the marker delivery device and biopsy needle provided in this application. Figure 6 Cross-sectional view of a portion of the structure of the marker delivery device and biopsy needle provided in this application. Figure 1 , Figure 8 for Figure 7 Sectional view at point BB.

[0056] In one embodiment of this application, the marker delivery device includes:

[0057] The elongated cannula 100 has an outlet 101 connecting its interior and exterior. The interior of the elongated cannula 100 is used to house the marker 10. The elongated cannula 100 is inserted into the biopsy needle 20, and the outlet 101 faces the sampling window 23 of the biopsy needle 20.

[0058] The support sleeve 210 is provided with a fitting hole 211. The fitting hole 211 has an opening 212 that penetrates the side wall of the support sleeve 210. At least part of the slender insertion tube 100 is fitted into the fitting hole 211 through the opening 212, and the outlet 101 faces the opening 212, so that the marker 10 can enter the target tissue through the outlet 101, the opening 212, and the sampling window 23.

[0059] The outer wall of the slender insertion tube 100 is approximately tangent to the outer wall of the support sleeve 210 at the opening 212.

[0060] In practical applications, combined with Figure 1 , Figure 4 , Figure 5 After the biopsy needle 20 has completed the biopsy sampling, the biopsy needle 20 remains at the target tissue. The thin cannula 100 is inserted into the inner blade 22 of the biopsy needle 20, so that the outlet 101 of the thin cannula 100 is aligned with the sampling window 23 on the outer blade 21 of the biopsy needle 20. The user uses the pusher 300 inserted in the thin cannula 100 to push the marker 10 inside the thin cannula 100 to slide. The marker 10 enters the target tissue sequentially through the outlet 101 of the thin cannula 100 and the sampling window 23 of the biopsy needle 20, thereby realizing the implantation of the marker 10. On the one hand, there is no need to remove the biopsy needle 20 and re-puncture the marker delivery device, avoiding secondary puncture damage to the target tissue, which helps to reduce patient pain and reduces additional disturbance to the diseased tissue. On the other hand, it reduces the number of device replacement steps and eliminates the need to reposition the lesion, simplifying the overall surgical procedure and shortening the operation time. Furthermore, the marker 10 that leaves the marker delivery device can directly enter the biopsy sampling point, avoiding misplacement of the marker 10 and improving the effectiveness and reliability of the marking.

[0061] The technical solution of this application increases the overall outer diameter of the front end of the marker delivery device by sleeved with a support sleeve 210 on the outside of the slender cannula 100, and reduces the dimensional difference between the front end and the inner diameter of the inner blade tube 22 of the biopsy needle 20. This reduces the shaking of the marker delivery device within the biopsy needle 20. On the one hand, it facilitates the alignment of the outlet 101 with the sampling window 23, reducing the risk of the marker 10 getting stuck between the outlet 101 and the sampling window 23. On the other hand, it improves the stability when moving the marker 10, which helps reduce discomfort to the patient. Furthermore, combined with... Figure 2 , Figure 3 and Figure 6The outer wall of the slender cannula 100 is approximately tangent to the outer wall of the support sleeve 210 at the opening 212, so that the outlet 101 on the slender cannula 100 can be located on or close to the outer peripheral surface of the support sleeve 210. When the marker delivery instrument is inserted into the biopsy needle 20 and the outlet 101 is opposite to the sampling window 23, the outlet 101 on the slender cannula 100 is more likely to approach the sampling window 23, reducing the distance between the outlet 101 and the sampling window 23, further reducing the risk of the marker 10 getting stuck between the outlet 101 and the sampling window 23, and ensuring that the marker 10 can be successfully implanted into the target tissue through the sampling window 23. In addition, the fitting hole 211 has an opening 212 located on the side wall of the support sleeve 210. When the delivery tube is assembled with the support sleeve 210, the delivery tube can be inserted into the fitting hole 211 radially along the support sleeve 210 through this opening 212, rather than being inserted into the fitting hole 211 axially from the end of the support sleeve 210. This reduces the relative displacement distance between the support sleeve 210 and the delivery tube during the assembly process, which reduces the processing accuracy requirements of the support sleeve 210 and the delivery tube, reduces the manufacturing and assembly difficulty, and reduces the powder falling off due to friction during the assembly process. This reduces the risk of powder entering the implanted tissue and reduces the adverse effects of marker implantation surgery.

[0062] In some embodiments, the front end of the elongated cannula 100 is completely received within the fitting hole 211, and the minimum radial distance between the outer wall of the elongated cannula 100 and the outer wall of the support sleeve 210 (e.g., ...) is... Figure 3 (As shown in H1) less than or equal to 0.5 mm.

[0063] Specifically, refer to Figure 2 and Figure 3Along the axial direction of the slender cannula 100, the front end of the slender cannula 100 is completely housed within the fitting hole 211 of the support sleeve 210, and the front end of the slender cannula 100 is not exposed at the opening 212. This ensures that the front end of the entire marker delivery device forms a uniform outer contour with the support sleeve 210, which helps to ensure the protective effect of the support sleeve 210 on the front end of the slender cannula 100. Furthermore, during the process of the device entering and exiting the biopsy needle 20, it avoids problems such as scraping or snagging between the slender cannula 100 and the internal components of the biopsy needle 20. This not only improves the smoothness of the marker delivery device entering and exiting the biopsy needle 20, but also reduces the risk of damage to the slender cannula 100 during the process of entering and exiting the biopsy needle 20. Along the radial direction of the slender cannula 100, the minimum distance between the outer wall of the slender cannula 100 and the outer wall of the support sleeve 210 is no greater than 0.5 mm, such as 0.5 mm, 0.3 mm, 0.1 mm, 0 mm, etc., where 0 mm means that the outer wall of the slender cannula 100 and the outer wall of the support sleeve 210 are tangent at the opening 212. By limiting the minimum distance to no more than 0.5 mm, the radial distance between the outlet 101 of the slender cannula 100 and the outer edge of the opening 212 of the support sleeve 210 is controlled within an extremely narrow range, so that the outlet 101 is flush or almost flush with the outer peripheral wall of the support sleeve 210. When the instrument is inserted into the biopsy needle 20 and the outlet 101 is aligned with the sampling window 23, the radial gap between the outlet 101 and the sampling window 23 is further reduced, further reducing the risk of jamming when the marker 10 passes through the sampling window 23 and improving the smoothness of marker 10 implantation.

[0064] In other embodiments, a portion of the outer wall of the front end of the elongated cannula 100 protrudes from the opening 212 beyond the outer wall of the support sleeve 210, and the maximum radial distance between the elongated cannula 100 protruding from the outer wall of the support sleeve 210 and the outer wall of the support sleeve 210 is (e.g., ...). Figure 14 (As shown in H2) less than or equal to 0.5 mm.

[0065] Specifically, refer to Figure 14The front end of the slender cannula 100 is not completely retracted into the fitting hole 211, but protrudes slightly outward from the support sleeve 210 through the opening 212. The outlet 101 of the slender cannula 100 is set towards the opening 212. Therefore, the outlet 101 is located in the tube wall area of ​​the part of the slender cannula 100 that protrudes from the opening 212. When the marker delivery instrument penetrates into the biopsy needle 20, the slightly convex outer wall of the slender cannula 100 can be further close to the inner wall surface of the biopsy needle 20, making the radial distance between the outlet 101 and the sampling window 23 of the biopsy needle 20 closer, further reducing the radial interval between the outlet 101 and the sampling window 23 of the biopsy needle 20, further reducing the risk of the marker 10 getting stuck when passing through the sampling window 23, and improving the smoothness of the marker 10 implantation. Along the radial direction of the slender cannula 100, the maximum distance between the slender cannula 100 protruding from the outer wall of the support sleeve 210 and the outer wall of the support sleeve 210 is no more than 0.5 mm, such as 0.5 mm, 0.3 mm, 0.1 mm, etc. This ensures that the maximum distance between the slender cannula 100 protruding from the support sleeve 210 is within 0.5 mm, guaranteeing that the protruding outer wall of the slender cannula 100 only forms a small bulge, reducing the risk of the slender cannula 100 scraping or snagging with the internal components of the biopsy needle 20. This not only helps to improve the smoothness of the marker delivery instrument entering and exiting the biopsy needle 20, but also reduces the risk of damage to the slender cannula 100 during the process of entering and exiting the biopsy needle 20.

[0066] In one embodiment, the marker delivery device further includes a plug 220. The front end of the slender cannula 100 is provided with a notch 102 that penetrates the inside and outside of the slender cannula 100. The plug 220 seals the front end of the slender cannula 100 and together with the inner wall of the notch 102 forms an outlet 101.

[0067] Specifically, refer to Figure 2 , Figure 9 and Figure 10 The plug 220 is used to seal the front end of the slender cannula 100, that is, to close the channel opening along its own axial direction on the front side of the slender cannula 100, ensuring that the marker 10 can only be released from the side wall outlet 101, reducing the risk of the marker 10 getting stuck in the slender cannula 100. In addition, a notch 102 is machined at the end of the front end of the slender cannula 100, and then it is surrounded by the plug 220 to form the outlet 101. The manufacturing method is simple. Especially for the slender cannula 100 with a small inner diameter, machining a notch 102 at the end reduces the manufacturing difficulty and improves the processing yield compared to opening a hole in the side wall.

[0068] In one embodiment, the plug 220 and the support sleeve 210 are an integral structure.

[0069] Specifically, refer to Figure 7 and Figure 9The plug 220 and the support sleeve 210 are integrally formed, which reduces the number of parts and assembly steps. When the slender cannula 100 is radially assembled into the fitting hole 211 through the opening 212 on the side wall of the support sleeve 210, the front end of the slender cannula 100 is also aligned with the plug 220, so that the plug 220 directly seals the front opening of the slender cannula 100, preventing the marker 10 from falling out of the front end of the slender cannula 100. In addition, the support sleeve 210 is located on the side wall of the slender cannula 100, and the plug 220 is located at the front end of the slender cannula 100. The integral configuration of the plug 220 and the support sleeve 210 helps to improve the protection of the front end of the slender cannula 100 and enhances the reliability of the connection between the two and the slender cannula 100, reducing the risk of the plug 220 or the support sleeve 210 falling off the slender cannula 100.

[0070] In one embodiment, the outer diameter of the end of the plug 220 away from the elongated cannula 100 decreases in the direction away from the elongated cannula 100.

[0071] Specifically, refer to Figure 7 and Figure 9 The end of the plug 220 that faces away from the slender cannula 100, i.e., the front end of the plug 220, is also the foremost point of the entire marker delivery device when inserted into the biopsy needle 20. The outer diameter of the front end of the plug 220 decreases along the axial direction away from the slender cannula 100, causing the front end of the plug 220 to gradually narrow, forming a guide structure, such as a cone or frustum shape. The narrowed front end of the plug 220 makes it easier to insert into the biopsy needle 20, thereby improving the convenience of inserting the marker delivery device into the biopsy needle 20.

[0072] In one embodiment, the inner wall of the fitting hole 211 is provided with a receiving groove 213, and a gel structure is provided in the receiving groove 213. The gel structure connects the inner wall of the receiving groove 213 and the outer wall of the slender insertion tube 100.

[0073] Specifically, refer to Figure 9 and Figure 10 Before assembling the slender cannula 100 with the support sleeve 210, adhesive is injected into the receiving groove 213 provided on the inner wall of the fitting hole 211 of the support sleeve 210. After the slender cannula 100 is assembled into the fitting hole 211 through the opening 212 on the side wall of the support sleeve 210, the adhesive in the receiving groove 213 cures to form a colloidal structure, connecting the inner wall of the receiving groove 213 and the outer wall of the slender cannula 100, thus achieving adhesive fixation of the slender cannula 100 in the fitting hole 211. This secure fixation avoids axial movement and circumferential rotation after assembly, and facilitates assembly, which is beneficial to improving the manufacturing efficiency of the marker delivery device. In addition, the receiving groove 213 provides space for the adhesive, preventing turbulence between the inner wall of the fitting hole 211 and the outer wall of the slender cannula 100, and improving the convenience of the adhesive application operation.

[0074] In one embodiment, the receiving groove 213 extends along the axial direction of the fitting hole 211; and / or,

[0075] The receiving groove 213 extends along the circumferential direction of the fitting hole 211.

[0076] Specifically, the inner wall of the fitting hole 211 may be provided with only a receiving groove 213 extending along the axial direction, or only a receiving groove 213 extending along the circumferential direction, or both types of receiving grooves 213 may be provided. Specifically, in this embodiment, referring to... Figure 8 and Figure 9 Along the axial direction of the support sleeve 210, multiple receiving grooves 213 are provided at intervals on the inner wall of the fitting hole 211. Each receiving groove 213 extends along the axial direction of the fitting hole 211, which further improves the firmness and uniformity of the bonding and fixing of the support sleeve 210 and the slender insertion tube 100.

[0077] In one embodiment, the width of the opening 212 is adjustable, allowing the elongated cannula 100 to enter the fitting hole 211 through the opening 212, while the periphery of the opening 212 prevents the elongated cannula 100 from leaving the fitting hole 211 through the opening 212. When the elongated cannula 100 is assembled with the support sleeve 210, the width of the opening 212 is increased, allowing the elongated cannula 100 to be inserted into the fitting hole 211 radially along the support sleeve 210 through the opening 212; after the elongated cannula 100 enters the fitting hole 211, the width of the opening 212 is decreased, and the periphery of the opening 212 forms a limiting barrier for the elongated cannula 100, preventing the elongated cannula 100 from leaving the fitting hole 211 through the opening 212, thus ensuring the firmness and reliability of the assembly between the elongated cannula 100 and the support sleeve 210. The adjustable width of the opening 212 can be achieved in various ways, such as: the side walls around the opening 212 are made of elastic material, or the opening 212 is formed between two sets of opposing suspended elastic arms, or the side walls on both sides of the opening 212 are separately set and configured with corresponding sets of buckles and holes, and the buckles are inserted into different holes to form different opening 212 widths, etc.

[0078] In one embodiment, the opening 212 has two opposing opening walls, wherein at least one opening wall is configured to be resilient so that the width of the opening 212 is adjustable.

[0079] Specifically, the opening 212 has two opposing and spaced-apart opening walls on both sides. The distance between the two opening walls is the width of the opening 212. One of the opening walls may have elastic deformation capability, or both opening walls may have elastic deformation capability. By changing the distance between the two opening walls by the elastic deformation capability of the opening walls themselves, the width of the opening 212 can be adjusted. No additional parts are required, the structure is simple, easy to manufacture, and the disassembly and assembly steps are simple and quick.

[0080] During assembly, the slender cannula 100 is inserted into the opening 212, causing the elastic opening wall to deform and retract, thus widening the opening 212. The slender cannula 100 can then pass through the widened opening 212 and enter the fitting hole 211. After the slender cannula 100 enters the fitting hole 211, the elastic opening wall recovers its deformation due to its own elasticity, reducing the distance between the two opening walls and returning to its natural state. At this time, the width of the opening 212 is smaller than the outer diameter of the slender cannula 100, preventing the slender cannula 100 from exiting the fitting hole 211 from the opening 212.

[0081] In one embodiment, the marker delivery device further includes a pusher 300, the front end of which is axially slidably inserted into the elongated cannula 100, and the rear end of which extends outside the elongated cannula 100 to drive the marker 10 to slide toward the outlet 101.

[0082] Specifically, in combination Figure 1 , Figure 4 as well as Figures 10 to 12 The front end of the pusher 300 enters the elongated cannula 100 from the side away from the outlet 101 and is slidably mounted inside the elongated cannula 100 along its axial direction. The rear end of the pusher 300 extends outside the elongated cannula 100 as the force-applying end. Before use, the marker 10 is pre-placed inside the elongated cannula 100, located between the front end of the pusher 300 and the outlet 101. When a pushing force is applied to the rear end of the pusher 300, the pusher 300 slides along the elongated cannula 100 towards the outlet 101, pushing the marker 10 to move synchronously, driving the marker 10 towards the outlet 101, and finally passing through the outlet 101 of the elongated cannula 100, the opening 212 of the support sleeve 210, and the sampling window 23 of the biopsy needle 20 in sequence, entering the target tissue of the implanted object. By using the pusher 300 to apply a pushing force to the marker 10 inside the slender cannula 100, the marker 10 can be pushed and implanted. The operation is simple and highly reliable. In addition, based on the length of the pusher 300 extending into the slender cannula 100, the user can also easily predict whether the marker 10 has been pushed into the target tissue, reducing the risk of marker 10 implantation failure.

[0083] In one embodiment, the pusher 300 includes:

[0084] The push needle portion 310 has its front end slidably inserted inside the elongated cannula 100, and its rear end extends outward from the elongated cannula 100 in a direction away from the outlet 101. The push needle portion 310 is used to drive the marker 10 to slide towards the outlet 101; and

[0085] The force-applying part 320 is located at the rear end of the pusher part 310, and at least part of the force-applying part 320 protrudes from the outer wall of the pusher part 310.

[0086] Specifically, in combination Figure 1 , Figure 4 as well as Figures 10 to 12 The pusher 300 includes a pusher part 310 and a force-applying part 320. The front end of the pusher part 310 slides through the elongated cannula 100 to transmit pushing force to the marker 10 inside the elongated cannula 100, and the rear end extends to the outside of the elongated cannula 100. The force-applying part 320 is disposed at the rear end of the pusher part 310, and at least part of the force-applying part 320 protrudes from the outer wall of the pusher part 310. That is, the force-applying part 320 forms a protruding structure in the radial direction of the pusher part 310, protruding on one, two or more sides of the pusher part 310. The user presses or pushes the force-applying part 320 to drive the pusher part 310 to move. The force-applying part 320 increases the contact area with the user, making it easier for the user to apply force.

[0087] In one embodiment, the marker delivery device further includes a grip structure 400, which includes two first handles 420 disposed opposite to each other on the rear end of the elongated cannula 100.

[0088] Specifically, in combination Figure 1 , Figure 4 and Figure 12 The grip structure 400 includes a sleeve portion 410 and a first handle 420. The sleeve portion 410 is fitted onto the rear end of the slender cannula 100 and fixed to the rear end of the slender cannula 100, ensuring the connection strength between the grip structure 400 and the slender cannula 100. The push needle portion 310 is slidably inserted through the sleeve portion 410. One end of the first handle 420 is fixed to the outer wall of the sleeve portion 410, and the other end extends away from the sleeve portion 410. A first handle 420 is provided on each of the opposite sides of the sleeve portion 410. When using it, the user can adopt an operation method similar to that of injecting a slender cannula, hooking the first handle 420 with the index and middle fingers respectively, and pushing the force application portion 320 with the thumb to move the push needle portion 310 toward the front end of the slender cannula 100. The operation is simple and convenient.

[0089] In one embodiment, the marker delivery device further includes a limiting member 500, which is detachably disposed on the gripping structure 400 and / or the push needle portion 310 and is located between the gripping structure 400 and the force application portion 320. The limiting member 500 is used to directly or indirectly abut against the gripping structure 400 and the force application portion 320 to prevent the push needle portion 310 from sliding toward the outlet 101.

[0090] Specifically, refer to Figure 12 and Figure 13 The limiting member 500 is detachable. When the limiting member 500 is installed, it prevents the push needle part 310 from sliding towards the outlet 101. Even if the force application part 320 is accidentally touched, the push needle part 310 cannot move forward and will not push the marker 10. This avoids accidental push of the marker 10 during transportation, storage, surgical preparation and other stages. When it is necessary to implant the marker 10, the limiting member 500 is removed, and the limiting member 500 stops the push needle part 310. The push needle part 310 can slide normally along the axial direction to complete the push operation of the marker 10. The limiting member 500 can be detachably provided on the gripping structure 400, for example, by adopting a buckle or pin structure, to prevent the force-applying part 320 from moving towards the outlet 101, thereby restricting the sliding of the push needle part 310; the limiting member 500 can also be detachably provided on the push needle part 310, for example, by adopting a limiting ring or buckle structure, sleeved or snapped onto the outer wall of the push needle part 310, and abutting against the end face of the gripping structure 400, thereby restricting the sliding of the push needle part 310 towards the outlet 101; the limiting member 500 can also be provided on both the gripping structure 400 and the push needle part 310 to form a double limiting, further improving the reliability of the anti-accidental touch function.

[0091] In one embodiment, the limiting member 500 includes:

[0092] The sleeve 510 has a notch 511 extending through its interior and exterior. The sleeve 510 is fitted onto the rear end of the push needle portion 310 through the notch 511 to prevent the push needle portion 310 from sliding towards the outlet 101; or the sleeve 510 may detach from the rear end of the push needle portion 310 through the notch 511, allowing the push needle portion 310 to slide towards the outlet 101.

[0093] The second handle 520 protrudes from the outer wall of the sleeve 510.

[0094] Specifically, in combination Figure 12 and Figure 13The limiting component 500 includes a sleeve 510 and a second handle 520. The sleeve 510 is provided with a notch 511, which allows the sleeve 510 to be radially fitted onto or detached from the rear end of the push needle part 310 through the notch 511, thereby realizing a detachable connection between the sleeve 510 and the push needle part 310. The structure is simple and the operation is convenient. When the sleeve 510 is fitted onto the rear end of the pusher needle part 310, one end of the sleeve 510 abuts against the side of the gripping structure 400 facing the force-applying part 320, and the other end abuts against the force-applying part 320, supporting itself between the force-applying part 320 and the gripping structure 400, preventing the force-applying part 320 from approaching the gripping structure 400, thus preventing the pusher needle part 310 from moving forward toward the outlet 101. When it is necessary to release the limit, the second handle 520 applies force to the sleeve 510, causing the sleeve 510 to detach from the pusher needle part 310 through the notch 511 and leave the space between the gripping structure 400 and the force-applying part 320, allowing the force-applying part 320 and the pusher needle part 310 to move forward and push the marker 10 normally. The sleeve 510, which wraps around the rear end of the pusher needle part 310 in a ring shape, can provide a limit function in the circumferential direction of the pusher needle part 310, reducing the risk of limit failure. The second handle 520 is located on the outer wall of the sleeve 510, which makes it convenient for users to apply force and grip, thereby improving the ease of disassembly and assembly of the limit component 500.

[0095] In one embodiment, the marker pushing device further includes an elastic element 600 disposed between the gripping structure 400 and the force-applying part 320, for generating an elastic force that drives the force-applying part 320 to move away from the gripping structure 400.

[0096] Specifically, refer to Figure 1 and Figure 12 The elastic element 600 is disposed between the grip structure 400 and the force application part 320. When the user drives the pusher 300 to slide forward, the elastic element 600 is compressed, generating a reverse elastic force, that is, an elastic force that drives the force application part 320 to move away from the grip structure 400. This elastic force will transmit a certain resistance feedback to the user's hand through the force application part 320. As the user continues to push the force application part 320 forward, the resistance feedback transmitted to the user's hand by the elastic element 600 gradually increases, so that the user can judge the forward speed and stroke of the pusher 300 by feel, reducing the risk of misalignment of the marker 10 or tissue damage caused by excessive or too fast pushing force, thereby improving the stability of pushing the marker 10. Specifically, in this embodiment, when the limiting member 500 is installed at the rear end of the push pin part 310, the elastic member 600 is disposed between the limiting member 500 and the force application part 320 and is in a compressed state. When the limiting member 500 is removed, the elastic member 600 restores a certain deformation, and its two ends abut against the holding structure 400 and the force application part 320 respectively. At this time, the elastic member 600 can still maintain the compressed state or be in a natural state.

[0097] This application also proposes a tissue marking device, comprising:

[0098] Marker 10; and

[0099] The aforementioned marker delivery device is used to transfer marker 10 into the target tissue.

[0100] The specific structure of the marker delivery device is as described in the above embodiments. Since this tissue marking device adopts all the technical solutions of all the above embodiments, it has at least all the beneficial effects brought about by the technical solutions of the above embodiments, which will not be described in detail here.

[0101] In one embodiment, the marker 10 is made of shape memory metal. The marker 10 unfolds into a strip shape inside the elongated cannula 100 and extends along the elongated cannula 100. When the marker 10 leaves the elongated cannula 100, the marker 10 at least partially resets and bends to form a curved structure.

[0102] Specifically, the marker 10 is made of shape memory metal, which possesses a shape memory effect. This material deforms under specific conditions (such as temperature changes or external forces) and returns to its original shape when the triggering conditions disappear. Specifically, in its free state without external force, the marker 10 is an open ring, i.e., not a completely closed ring. By applying external force, the overall shape of the marker 10 can be transformed from a ring to an approximately straight or arc-shaped elongated form, such as... Figure 10 As shown, this allows the marker 10 to be inserted into the elongated cannula 100. At this point, the inner wall of the elongated cannula 100 exerts a reaction force on the marker 10, preventing it from returning to an open ring shape. When the marker 10 is pushed to the outlet 101 by the pusher 300, the end of the marker 10 facing the outlet 101 loses the restriction of the inner wall of the elongated cannula 100. Relying on the shape memory effect of the shape memory metal, the marker 10 will autonomously return to its initial open ring shape, such as... Figure 11 As shown, during the process of restoring the ring-shaped curvature, the marker 10 enters the target tissue through the outlet 101 and sampling window 23, thus achieving the implantation operation. Before implantation, the marker 10 is unfolded by external force to facilitate its insertion into the marker delivery device, improving the ease of assembly between the marker 10 and the device. Once the unfolded marker 10 is delivered into the target tissue, it is freed from external force. The shape memory metal material causes the marker 10 to return to an open ring shape. During this recovery process, the two ends of the open ring curl towards the center, forming a curved structure that holds the surrounding tissue, ensuring the marker 10 is stably anchored within the tissue and preventing displacement or detachment. This guarantees the accurate positioning of the marker 10 within the tissue, thereby ensuring precise location of the lesion during imaging examinations and providing a reliable positioning benchmark for subsequent diagnosis and treatment.

[0103] In this context, the marker 10 is in an open ring shape in its free state. The ring shape can be circular, but it is not limited to a circle. For example, it can be rectangular or pentagonal. There is no limitation here. "Open" means that the two ends of the marker 10 are not closed. For example, the two ends of the marker 10 can be spaced apart, connected to each other, or partially overlapped, as long as the functional requirements are met. There is no limitation here.

[0104] The above description is merely an exemplary embodiment of this application and does not limit the scope of protection of this application. Any equivalent structural transformations made based on the technical concept of this application and the contents of the specification and drawings of this application, or direct / indirect applications in other related technical fields, are included within the scope of protection of this application.

Claims

1. A marker delivery device, characterized in that, include: The long, thin cannula has an outlet that connects its interior and exterior. The interior of the long, thin cannula is used to contain a marker. The long, thin cannula is used to penetrate into a biopsy needle, and the outlet is directed toward the sampling window of the biopsy needle. as well as The support sleeve has a fitting hole with an opening that penetrates the side wall of the support sleeve. At least a portion of the slender cannula is fitted into the fitting hole through the opening, and the outlet faces the opening, so that the marker can enter the target tissue through the outlet, the opening, and the sampling window. The outer wall of the slender insertion tube is approximately tangent to the outer wall of the support sleeve at the opening.

2. The marker delivery device as described in claim 1, characterized in that, The front end of the slender cannula is completely contained within the sleeve hole, and the minimum distance between the outer wall of the slender cannula and the outer wall of the support sleeve along the radial direction of the slender cannula is less than or equal to 0.5 mm.

3. The marker delivery device as described in claim 1, characterized in that, The outer wall of the front end of the slender cannula protrudes from the opening onto the outer wall of the support sleeve, and the maximum distance between the slender cannula protruding from the outer wall of the support sleeve and the outer wall of the support sleeve along the radial direction of the slender cannula is less than or equal to 0.5 mm.

4. The marker delivery device as described in claim 1, characterized in that, The marker delivery device also includes a plug, and the front end of the slender cannula has a notch that penetrates the inside and outside of the slender cannula. The plug seals the front end of the slender cannula and together with the inner wall of the notch, forms the outlet.

5. The marker delivery device as described in claim 4, characterized in that, The plug and the support sleeve are an integral structure; and / or, The outer diameter of the end of the plug away from the slender cannula decreases in the direction away from the slender cannula.

6. The marker delivery device as described in claim 1, characterized in that, The inner wall of the fitting hole is provided with a receiving groove, and a colloidal structure is provided in the receiving groove. The colloidal structure connects the inner wall of the receiving groove and the outer wall of the slender insertion tube.

7. The marker delivery device as described in claim 6, characterized in that, The receiving groove extends along the axial direction of the fitting hole; and / or, The receiving groove extends along the circumferential direction of the fitting hole.

8. The marker delivery device as described in claim 1, characterized in that, The marker delivery device further includes a pusher, the front end of which is axially slidably inserted into the elongated cannula, and the rear end of which extends outside the elongated cannula to drive the marker to slide toward the outlet.

9. The marker delivery device as described in claim 1, characterized in that, The marker delivery device also includes a gripping structure, which includes two first handles positioned opposite each other on both sides of the rear end of the slender cannula.

10. A tissue marking device, characterized in that, include: Markers; as well as The marker delivery device as described in any one of claims 1 to 9, wherein the marker delivery device is used to transfer the marker into the target tissue.

11. The tissue marking device as claimed in claim 10, characterized in that, The marker is made of shape memory metal. The marker unfolds into a long strip inside the slender cannula and extends along the slender cannula. When the marker leaves the slender cannula, the marker at least partially resets and bends to form a curved structure.

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