Liquid crystal emulsions containing lecithin, methods of making and using the same

Abstract

This invention discloses a liquid crystal emulsion containing lecithin, its preparation method, and its application. The liquid crystal emulsion containing lecithin, based on a total mass of 100 parts, comprises the following components in parts by mass: 1-5 parts lecithin; 0.5-5 parts ginsenosides; 3-15 parts liquid oil; 1-5 parts solid oil; 0.1-1 parts preservative; 1-10 parts humectant; and water; wherein the mass ratio of lecithin to ginsenosides is (1.5-4):1. This liquid crystal emulsion containing lecithin not only forms a stable liquid crystal structure and exhibits excellent stability, but is also gentle on the skin and has a soft feel.

Description

Technical Field

[0001] This invention relates to a liquid crystal emulsion containing lecithin, its preparation method, and its application. Background Technology

[0002] Lecithin is a phosphate-containing lipid compound found in the cell membranes and protoplasm of living organisms. Based on its source, lecithin can be divided into plant-derived and animal-derived types. Plant-derived lecithin is mainly derived from soybeans, while animal-derived lecithin is mainly derived from animal blood, offal, and egg yolks, with egg yolks containing the highest concentration.

[0003] Lecithin possesses strong surface activity and colloidal properties, and its natural origin makes it safe and biocompatible. Furthermore, lecithin has multiple functions, including emulsification, dispersion, wetting, moisturizing, anti-oxidation, penetration, conditioning, softening, and skin moisturizing. Therefore, it can be added to various cosmetic formulations as an emulsifier, sustained-release carrier, moisturizer, and antioxidant.

[0004] Liquid crystals are thermodynamically stable phases intermediate between crystalline and liquid crystal states. They exist in a partially dissolved state and possess a certain degree of thermodynamic stability. In recent years, emulsions containing liquid crystal structures have attracted widespread attention from scholars in the cosmetics industry. These emulsions primarily consist of emulsifiers with unique structures combined with suitable oils to form an ordered, oriented arrangement. Cosmetics containing liquid crystal structures can increase the stability of emulsions, enhance moisturizing properties, control drug release, and provide a superior skin feel.

[0005] Chinese invention patent application CN107260568A discloses a liquid crystal emulsion containing lecithin and its preparation method. The liquid crystal emulsion includes lecithin, auxiliary emulsifier, liquid oil, solid lipid, preservative and water. The lecithin is at least one of soybean lecithin, egg yolk lecithin and hydrogenated lecithin. Although the prepared liquid crystal emulsion can form Maltese cross liquid crystals and has good stability, the addition of a large amount of auxiliary emulsifier makes the resulting liquid crystal emulsion not gentle on the skin and has a poor skin feel.

[0006] In existing methods for preparing lecithin-containing liquid crystal emulsions, a large amount of emulsifier is often introduced to ensure that lecithin forms a stable liquid crystal structure. However, the addition of emulsifiers causes the resulting liquid crystal emulsion to have adverse effects on the skin, such as being harsh and lacking softness. This makes it impossible for existing lecithin-containing liquid crystal emulsions to achieve both a stable liquid crystal structure and stability while also being gentle and soft on the skin. Summary of the Invention

[0007] The technical problem this invention aims to solve is to overcome the shortcomings of existing liquid crystal emulsions containing lecithin, which cannot simultaneously achieve a stable liquid crystal structure and be gentle on the skin with a soft feel. This invention provides a liquid crystal emulsion containing lecithin, its preparation method, and its applications. This lecithin-containing liquid crystal emulsion not only forms a stable liquid crystal structure with excellent stability but also is gentle on the skin and has a soft feel.

[0008] The present invention solves the above-mentioned technical problems through the following technical solution: This invention provides a liquid crystal emulsion containing lecithin, which comprises the following components in parts by weight, based on a total mass of 100 parts: 1-5 parts lecithin; Ginsenosides 0.5-5 parts; 3-15 parts of liquid oil; 1-5 parts of solid fats; Preservative 0.1-1 part; 1-10 parts of moisturizer; water; The mass ratio of the lecithin to the ginsenoside is (1.5-4):1.

[0009] There is no record of the practical application of ginsenosides in liquid crystal emulsions containing lecithin in the existing technology. Through research, it has been found that in this invention, by specially introducing ginsenosides into the liquid crystal emulsion containing lecithin, due to the special structure of ginsenosides, they can be inserted into the molecular layer of lecithin. When compounded with a specific amount, the resulting liquid crystal emulsion containing lecithin can form a stable liquid crystal structure with excellent stability, while also taking into account the characteristics of being gentle on the skin and having a soft feel.

[0010] In this invention, the viscosity of the liquid crystal emulsion containing lecithin can be 1000-10000 mPa·s. This gives it good fluidity, allowing it to be poured or allowed to flow by gravity, making it a liquid flow system.

[0011] In this invention, the ginsenosides can be commercially available ginsenosides, which are the core triterpenoid active ingredients in plants of the genus Panax (such as ginseng and American ginseng) in the Araliaceae family. Their basic skeleton is a tetracyclic triterpenoid (dammarane type) composed of 30 carbon atoms, and a few are pentacyclic triterpenoids (oleanolic acid type). Generally, they contain one or more core monomers of ginsenosides Rg3, Rb1, Rb2, Rb3, Rc, Rd, Rh2, Re, Rg1, Rg2 and Rh1.

[0012] In some preferred embodiments, the mass ratio of the lecithin to the ginsenoside is (1.5-3):1, for example, 2:1 or 2.5:1.

[0013] In some preferred embodiments, the liquid crystal emulsion containing lecithin does not contain any surfactants other than lecithin; preferably, the surfactant is an emulsifier. The emulsifier can be any emulsifier conventionally used in the art, preferably including anionic emulsifiers, cationic emulsifiers, nonionic emulsifiers, and zwitterionic emulsifiers, such as sodium lauryl sulfate, sodium lauryl ether sulfate, potassium cetyl phosphate, sodium stearoyl glutamate, hexadecyl trimethylammonium chloride, glyceryl monostearate, polysorbate (Tween), sorbitan fatty acid esters (Span), polyoxyethylene sorbitan fatty acid esters, fatty alcohol polyoxyethylene ethers, polyethylene glycol fatty acid esters, ethoxylated castor oil, and fatty acid monoglycerides. The invention comprises one or more of sucrose monostearate, cetearyl alcohol polyether, poloxamer, and polyglycerol emulsifiers; wherein the polyglycerol emulsifiers include one or more of polyglycerol fatty acid esters (e.g., one or more of polyglycerol lauryl esters, polyglycerol stearate compounds, and polyglycerol isostearate compounds), polyglycerol ethers (e.g., one or more of polyglycerol alkyl ethers, polyglycerol lauryl ethers, polyglycerol oleyl alcohol ethers, polyglycerol cetyl ethers, polyglycerol stearyl alcohol ethers, and polyglycerol isomeric fatty alcohol ethers), and polyglycerol condensed castor oil esters. The emulsifiers may also be referred to as co-emulsifiers or auxiliary emulsifiers. It can be understood that reagents conventionally capable of emulsifying in the art are within the scope of the emulsifiers of this invention. In this invention, the surfactant may be an amphiphilic compound whose molecular structure simultaneously contains a hydrophilic polar group and a hydrophobic (lipophilic) nonpolar group, which, upon dissolving in a liquid, can significantly reduce the surface tension of the liquid and the interfacial tension between oil and water; the surfactant is not limited to emulsifiers.

[0014] In this invention, the lecithin can be the lecithin conventionally used in the art, preferably including hydrogenated lecithin and / or egg yolk lecithin, such as hydrogenated lecithin.

[0015] In this invention, the liquid oil can be any liquid oil conventionally used in the art, preferably one or more of vegetable oil, animal oil, and synthetic oil.

[0016] The plant oils preferably include one or more of the following: jojoba oil, macadamia nut oil, olive oil, sweet almond oil, coconut oil, castor oil, sunflower seed oil, and wheat germ oil.

[0017] The animal fats preferably include one or more of mink oil, shark liver oil, flounder oil, turtle oil, snake oil, white oil, and lanolin.

[0018] The synthetic oil preferably includes one or more of polyoxyethylene-polyoxypropylene lanolin, squalane, polydimethylsiloxane, polymethylphenylsiloxane, cyclic methylsiloxane, caprylic / capric triglyceride, isopropyl palmitate, isochetane, isooctyl palmitate, and isooctyl isostearate, for example, caprylic / capric triglyceride.

[0019] In this invention, the solid oil can be a conventionally used solid oil in the art, preferably one or more of fatty alcohols, steroids, glycerides, and waxes. The fatty alcohols preferably include cetearyl alcohol and / or stearyl alcohol, for example, cetearyl alcohol. The waxes include hydrogenated castor oil and / or pentaerythritol distearate.

[0020] In this invention, the preservative can be a preservative conventionally used in the art, preferably one or more of parabens, benzyl alcohol, phenoxyethanol (phenylethanol), 2-bromo-2-nitropropane-1,3-propanediol, hexamethylenetetramine derivatives, imidazolidinyl urea, dehydroacetic acid, sorbic acid, Kathon, glyceryl monolaurate, diazolidinyl urea, hydroxymethylhydantoin, and dimethyloldimethylhydantoin, for example, phenoxyethanol. The paraben preservative preferably includes one or more of methylparaben, ethylparaben, propylparaben, butylparaben, isobutylparaben, isopropylparaben, pentylparaben, and phenylparaben.

[0021] In this invention, the humectant can be a humectant commonly used in the art, preferably a polyol humectant, and more preferably includes one or more of glycerin, propylene glycol, 1,3-butanediol, dipropylene glycol, sorbitol, xylitol, erythritol and polyethylene glycol, for example, glycerin.

[0022] In this invention, the liquid crystal emulsion containing lecithin may further include a thickener. The thickener may be a conventional thickener used in the art, preferably one or more of carbomer, hydroxyethyl acrylate-sodium acryloyldimethyl taurate copolymer, sodium acrylate-sodium acryloyldimethyl taurate copolymer, acrylic-C10-30 alkanol acrylate crosslinking polymer, and acrylate-C10-30 alkanol acrylate crosslinking polymer, for example, hydroxyethyl acrylate-sodium acryloyldimethyl taurate copolymer.

[0023] The preferred mass fraction of the thickener is 0.1-2 parts, for example, 0.6 parts.

[0024] In some preferred embodiments, the lecithin is in the form of 2-4 parts by weight, for example, 3 parts.

[0025] In some preferred embodiments, the ginsenosides are present in 1-3 parts by mass, for example, 2 parts.

[0026] In some preferred embodiments, the liquid oil is present in parts by mass of 5-15, for example, 8, 10 or 13 parts.

[0027] In some preferred embodiments, the solid grease is 1-3 parts by mass, for example, 2 parts.

[0028] In some preferred embodiments, the preservative is present in parts by weight of 0.1-0.7 parts, for example, 0.5 parts.

[0029] In some preferred embodiments, the humectant is present in 5-10 parts by weight, for example, 7 parts.

[0030] In some preferred embodiments, the water is in the form of 65-80 parts by mass, preferably 66-78 parts, for example 66.9 parts, 71.9 parts, 75.9 parts, 76.9 parts or 77.9 parts.

[0031] In some specific embodiments, the liquid crystal emulsion containing lecithin includes 3 parts lecithin, 2 parts ginsenosides, 5 parts liquid oil, 2 parts solid oil, 0.5 parts preservative, 10 parts humectant, and 76.9 parts water.

[0032] In one specific embodiment, the liquid crystal emulsion containing lecithin comprises 3 parts hydrogenated lecithin, 2 parts ginsenosides, 5 parts caprylic / capric triglyceride, 2 parts cetearyl alcohol, 0.5 parts phenoxyethanol, 10 parts glycerin, and 76.9 parts water.

[0033] In some specific embodiments, the liquid crystal emulsion containing lecithin includes 4 parts lecithin, 2 parts ginsenosides, 5 parts liquid oil, 2 parts solid oil, 0.5 parts preservative, 10 parts humectant, and 75.9 parts water.

[0034] In one specific embodiment, the liquid crystal emulsion containing lecithin comprises 4 parts hydrogenated lecithin, 2 parts ginsenosides, 5 parts caprylic / capric triglyceride, 2 parts cetearyl alcohol, 0.5 parts phenoxyethanol, 10 parts glycerin, and 75.9 parts water.

[0035] In some specific embodiments, the liquid crystal emulsion containing lecithin includes 3 parts lecithin, 1 part ginsenoside, 5 parts liquid oil, 2 parts solid oil, 0.5 parts preservative, 10 parts humectant, and 77.9 parts water.

[0036] In one specific embodiment, the liquid crystal emulsion containing lecithin comprises 3 parts hydrogenated lecithin, 1 part ginsenoside, 5 parts caprylic / capric triglyceride, 2 parts cetearyl alcohol, 0.5 parts phenoxyethanol, 10 parts glycerin, and 77.9 parts water.

[0037] In some specific embodiments, the liquid crystal emulsion containing lecithin includes 3 parts lecithin, 2 parts ginsenosides, 10 parts liquid oil, 2 parts solid oil, 0.5 parts preservative, 10 parts humectant, and 71.9 parts water.

[0038] In one specific embodiment, the liquid crystal emulsion containing lecithin comprises 3 parts hydrogenated lecithin, 2 parts ginsenosides, 10 parts caprylic / capric triglyceride, 2 parts cetearyl alcohol, 0.5 parts phenoxyethanol, 10 parts glycerin, and 71.9 parts water.

[0039] In some specific embodiments, the liquid crystal emulsion containing lecithin includes 3 parts lecithin, 2 parts ginsenosides, 15 parts liquid oil, 2 parts solid oil, 0.5 parts preservative, 10 parts humectant, and 66.9 parts water.

[0040] In one specific embodiment, the liquid crystal emulsion containing lecithin comprises 3 parts hydrogenated lecithin, 2 parts ginsenosides, 15 parts caprylic / capric triglyceride, 2 parts cetearyl alcohol, 0.5 parts phenoxyethanol, 10 parts glycerin, and 66.9 parts water.

[0041] This invention provides a method for preparing a lecithin-containing liquid crystal emulsion as described above, comprising the following steps: The liquid crystal emulsion containing lecithin is obtained by mixing the components of the liquid crystal emulsion.

[0042] In some preferred embodiments, the method for preparing the lecithin-containing liquid crystal emulsion includes the following steps: S1. Homogenize the oil phase mixture and the water to obtain a first homogenized mixture; wherein the oil phase mixture includes the lecithin, the ginsenosides, the liquid oil, the solid oil, and the moisturizer; S2. Homogenize the first homogenized mixture and the preservative.

[0043] In step S1, the homogenization temperature is preferably 75-90°C, for example, 85°C.

[0044] In step S1, the preferred rotational speed for homogenization is 4000-8000 rpm, for example, 5000 rpm.

[0045] In step S2, the homogenization temperature is preferably 50-70°C, for example, 60°C.

[0046] In step S2, the preferred rotational speed for homogenization is 4000-8000 rpm, for example, 5000 rpm.

[0047] In some more preferred embodiments, when the lecithin liquid crystal emulsion further includes a thickener, in step S2, before homogenizing the first homogenized mixture and the preservative, the first homogenized mixture and the thickener are first homogenized. The homogenization temperature is preferably 50-70°C, for example, 60°C; the homogenization speed is preferably 4000-8000 rpm, for example, 5000 rpm.

[0048] The present invention also provides an application of the liquid crystal emulsion containing lecithin as described above in the field of cosmetics.

[0049] The positive and progressive effects of this invention are as follows: The liquid crystal emulsion containing lecithin provided by this invention can form a stable liquid crystal structure under specific relative dosages of ginsenosides and lecithin, even without the addition of emulsifiers. It has a large number of liquid crystals, excellent stability, and can also produce a mild and non-irritating liquid crystal system that is gentle on the skin and has a soft feel.

[0050] In addition, the liquid crystal emulsion containing lecithin provided by the present invention also has anti-aging, repair and moisturizing effects. Attached Figure Description

[0051] Figure 1 This is a polarized light microscope image of the liquid crystal emulsion containing lecithin obtained in Example 1 of the present invention.

[0052] Figure 2 This is a polarized light microscope image of the liquid crystal emulsion containing lecithin obtained in Example 2 of the present invention.

[0053] Figure 3 This is a polarized light microscope image of the liquid crystal emulsion containing lecithin obtained in Example 3 of the present invention.

[0054] Figure 4 This is a polarized light microscope image of the liquid crystal emulsion containing lecithin obtained in Example 4 of the present invention.

[0055] Figure 5 This is a polarized light microscope image of the liquid crystal emulsion containing lecithin obtained in Example 5 of the present invention.

[0056] Figure 6 This is a polarized light microscope image of the lecithin-containing emulsion obtained in Comparative Example 1 of this invention.

[0057] Figure 7 This is a polarized light microscope image of the lecithin-containing emulsion obtained in Comparative Example 2 of this invention.

[0058] Figure 8 This is a polarized light microscope image of the lecithin-containing emulsion obtained in Comparative Example 3 of the present invention.

[0059] Figure 9 This is a polarized light microscope image of the lecithin-containing emulsion obtained in Comparative Example 4 of this invention. Detailed Implementation

[0060] The present invention will be further illustrated by way of embodiments below, but the present invention is not limited to the scope of the embodiments described herein.

[0061] The relevant source information for each raw material component in the following examples and comparative examples is shown in the table below:

[0062] In the following examples and comparative examples, homogenization was performed in a homogenizer, and the specific information is shown in the table below:

[0063] Example 1

[0064] Weigh out 3 grams of hydrogenated lecithin, 2 grams of ginsenosides, 5 grams of GTCC, 2 grams of cetearyl alcohol, and 10 grams of glycerin into beaker A.

[0065] Weigh 76.9 g of deionized water into beaker B. Heat both beakers to 85°C. Add the raw material from beaker A to beaker B and homogenize for 5 minutes at 5000 rpm. Then cool to 60°C, add 0.6 g of EMT10, and continue homogenizing for 2 minutes (60°C, 5000 rpm). Then add 0.5 g of phenoxyethanol and homogenize for another 2 minutes (60°C, 5000 rpm) to obtain a liquid crystal emulsion containing lecithin.

[0066] Example 2

[0067] Weigh out 4 grams of hydrogenated lecithin, 2 grams of ginsenosides, 5 grams of GTCC, 2 grams of cetearyl alcohol, and 10 grams of glycerin into beaker A.

[0068] Weigh 75.9 g of deionized water into beaker B. Heat both beakers to 85°C. Add the raw material from beaker A to beaker B and homogenize for 5 minutes at 5000 rpm. Then cool to 60°C, add 0.6 g of EMT10, and continue homogenizing for 2 minutes (60°C, 5000 rpm). Then add 0.5 g of phenoxyethanol and homogenize for another 2 minutes (60°C, 5000 rpm) to obtain a liquid crystal emulsion containing lecithin.

[0069] Example 3

[0070] Weigh out 3 grams of hydrogenated lecithin, 1 gram of ginsenoside, 5 grams of GTCC, 2 grams of cetearyl alcohol, and 10 grams of glycerin in beaker A.

[0071] Weigh 77.9 g of deionized water into beaker B. Heat both beakers to 85°C. Add the raw material from beaker A to beaker B and homogenize for 5 minutes at 5000 rpm. Then cool to 60°C, add 0.6 g of EMT10, and continue homogenizing for 2 minutes (60°C, 5000 rpm). Then add 0.5 g of phenoxyethanol and homogenize for another 2 minutes (60°C, 5000 rpm) to obtain a liquid crystal emulsion containing lecithin.

[0072] Example 4

[0073] Weigh out 3 grams of hydrogenated lecithin, 2 grams of ginsenosides, 10 grams of GTCC, 2 grams of cetearyl alcohol, and 10 grams of glycerin in beaker A.

[0074] Weigh 71.9 g of deionized water into beaker B. Heat both beakers to 85°C. Add the raw material from beaker A to beaker B and homogenize for 5 minutes at 5000 rpm. Then cool to 60°C, add 0.6 g of EMT10, and continue homogenizing for 2 minutes (60°C, 5000 rpm). Then add 0.5 g of phenoxyethanol and homogenize for another 2 minutes (60°C, 5000 rpm) to obtain a liquid crystal emulsion containing lecithin.

[0075] Example 5

[0076] Weigh out 3 grams of hydrogenated lecithin, 2 grams of ginsenosides, 15 grams of GTCC, 2 grams of cetearyl alcohol, and 10 grams of glycerin in beaker A.

[0077] Weigh 66.9 g of deionized water into beaker B. Heat both beakers to 85°C. Add the raw material from beaker A to beaker B and homogenize for 5 minutes at 5000 rpm. Then cool to 60°C, add 0.6 g of EMT10, and continue homogenizing for 2 minutes (60°C, 5000 rpm). Then add 0.5 g of phenoxyethanol and homogenize for another 2 minutes (60°C, 5000 rpm) to obtain a liquid crystal emulsion containing lecithin.

[0078] Comparative Example 1

[0079] Weigh out 3 grams of hydrogenated lecithin, 2 grams of cholesterol, 5 grams of GTCC, 2 grams of cetyl alcohol, and 10 grams of glycerol into beaker A.

[0080] Weigh 76.9 g of deionized water into beaker B. Heat both beakers to 85°C. Add the raw material from beaker A to beaker B and homogenize for 5 minutes at 5000 rpm. Then cool to 60°C, add 0.6 g of EMT10, and continue homogenizing for 2 minutes (60°C, 5000 rpm). Then add 0.5 g of phenoxyethanol and homogenize for another 2 minutes (60°C, 5000 rpm) to obtain an emulsion containing lecithin.

[0081] Comparative Example 2

[0082] Weigh out 3 grams of hydrogenated lecithin, 5 grams of GTCC, 2 grams of cetearyl alcohol and 10 grams of glycerol into beaker A.

[0083] Weigh 78.9 g of deionized water into beaker B. Heat both beakers to 85°C. Add the raw material from beaker A to beaker B and homogenize for 5 minutes at 5000 rpm. Then cool to 60°C, add 0.6 g of EMT10, and continue homogenizing for 2 minutes (60°C, 5000 rpm). Then add 0.5 g of phenoxyethanol and homogenize for another 2 minutes (60°C, 5000 rpm) to obtain an emulsion containing lecithin.

[0084] Comparative Example 3

[0085] Weigh out 2 grams of hydrogenated lecithin, 2 grams of ginsenosides, 5 grams of GTCC, 2 grams of cetearyl alcohol, and 10 grams of glycerin into beaker A.

[0086] Weigh 77.9 g of deionized water into beaker B. Heat both beakers to 85°C. Add the raw material from beaker A to beaker B and homogenize for 5 minutes at 5000 rpm. Then cool to 60°C, add 0.6 g of EMT10, and continue homogenizing for 2 minutes (60°C, 5000 rpm). Then add 0.5 g of phenoxyethanol and homogenize for another 2 minutes (60°C, 5000 rpm) to obtain an emulsion containing lecithin.

[0087] Comparative Example 4

[0088] Weigh out 3 grams of hydrogenated lecithin, 3 grams of ginsenosides, 5 grams of GTCC, 2 grams of cetearyl alcohol, and 10 grams of glycerin into beaker A.

[0089] Weigh 75.9 g of deionized water into beaker B. Heat both beakers to 85°C. Add the raw material from beaker A to beaker B and homogenize for 5 minutes at 5000 rpm. Then cool to 60°C, add 0.6 g of EMT10, and continue homogenizing for 2 minutes (60°C, 5000 rpm). Then add 0.5 g of phenoxyethanol and homogenize for another 2 minutes (60°C, 5000 rpm) to obtain an emulsion containing lecithin.

[0090] The amounts (in grams) of each component in the lecithin-containing liquid crystal emulsions obtained in Examples 1-5 and Comparative Examples 1-4 above are shown in Table 1.

[0091] Table 1

[0092] Note: In Table 1, " / " indicates that the component was not involved in the specific experiment.

[0093] Example 1

[0094] The liquid crystal emulsions containing lecithin obtained in Examples 1-5 and the emulsions containing lecithin obtained in Comparative Examples 1-4 were observed using a polarizing microscope. Specifically: A very small amount (approximately 0.1-0.5 mg) of the emulsion sample was taken with a needle tip, spread onto a glass slide, and gently pressed down with a coverslip to make it as thin as possible, thus preparing a microscope slide. The structure and quantity of Maltese cross liquid crystals were observed under a polarizing microscope, and evaluated based on a scoring criterion. The specific scoring results are shown in Table 2. Polarizing microscope images of the lecithin-containing liquid crystal emulsions obtained in Examples 1-5 are shown below. Figure 1-5 As shown, polarized light microscope images of the lecithin-containing emulsions obtained in Comparative Examples 1-4 are respectively shown in the following figures. Figure 6-9 As shown.

[0095] The specific evaluation criteria are as follows: It is evident that the number of liquid crystals is less than 20 bright spots, the ratio of the total area of ​​the liquid crystal bright spots to the total area of ​​the obtained polarized light microscope image is less than 1 / 3, and the size is not uniform, which is scored as 1 point; It is evident that the number of liquid crystals is less than 20 bright spots, the ratio of the total area of ​​the liquid crystal bright spots to the total area of ​​the obtained polarizing microscope image is less than 1 / 3, and the size is uniform, which is scored as 2 points; It is evident that there are no fewer than 20 bright spots in the liquid crystal, and the ratio of the total area of ​​the liquid crystal bright spots to the total area of ​​the obtained polarized light microscope image is more than 1 / 3 and less than 1 / 2, and the size is not uniform, which is scored as 3 points; It can be seen that there are no fewer than 20 bright spots in the liquid crystal, and the ratio of the total area of ​​the liquid crystal bright spots to the total area of ​​the obtained polarized light microscope image is more than 1 / 3 and less than 1 / 2, but the size is uniform, and it is scored as 4 points; It is evident that there are no fewer than 20 bright spots in the liquid crystal, and the ratio of the total area of ​​the liquid crystal bright spots to the total area of ​​the obtained polarized light microscope image is more than 1 / 2 and less than 2 / 3, but the size is not uniform, and it is scored as 5 points; It is evident that there are no fewer than 20 bright spots in the liquid crystal, and the ratio of the total area of ​​the liquid crystal bright spots to the total area of ​​the obtained polarizing microscope image is more than 1 / 2 and less than 2 / 3, and the size is uniform, which is scored as 6 points; It can be seen that there are no fewer than 20 bright spots in the liquid crystal, and the ratio of the total area of ​​the liquid crystal bright spots to the total area of ​​the obtained polarized light microscope image is more than 2 / 3, but the size is not uniform, and it is scored as 7 points; It can be seen that there are no fewer than 20 bright spots in the liquid crystal, the ratio of the total area of ​​the liquid crystal bright spots to the total area of ​​the obtained polarized light microscope image is more than 2 / 3, and the size is uniform, which is scored as 8 points.

[0096] Table 2

[0097] Depend on Figure 1-9 As shown in Table 2, the liquid crystal emulsions containing lecithin in Examples 1-5 of this invention exhibited obvious bright spots under a polarizing microscope, and their liquid crystal scores reached 5 or higher. This indicates that the obtained liquid crystal emulsions containing lecithin formed a large amount of liquid crystal and possessed excellent stability. Figure 1-9 It can be seen that the liquid crystal polarization in Example 1 is very obvious. In contrast, Comparative Examples 1-4 show little or no liquid crystal polarization, with liquid crystal scores below 2. Comparative Examples 1-2 did not use ginsenosides, resulting in a significant reduction in the amount of liquid crystal in the resulting emulsions. Even when Comparative Example 1 used the same amount of cholesterol instead of lecithin, the amount of liquid crystal was still significantly less. In Comparative Examples 3-4, the mass ratio of lecithin to ginsenosides was only 1:1, leading to a significant reduction in the amount of liquid crystal in the resulting liquid crystal emulsions containing lecithin. This may be because, compared to lecithin, excessive ginsenosides are detrimental to liquid crystal formation and can lead to decreased emulsion viscosity and reduced stability.

[0098] A comparison of Examples 1 and 2-3 shows that the relative amounts of lecithin and ginsenosides have a significant impact on the amount of liquid crystals in the resulting liquid crystal emulsion containing lecithin. In Example 2, the amount of lecithin relative to ginsenosides was increased. Although the morphology of the resulting liquid crystal emulsion containing lecithin became irregular, the amount of liquid crystals increased significantly. It can be inferred that the liquid crystal emulsion has excellent stability.

[0099] Compared to Example 1, Examples 4 and 5 added different amounts of liquid grease, from Figure 1It can be seen that the lecithin-containing liquid crystal emulsions obtained in Examples 4-5 can stably form liquid crystal structures. This indicates that the special structure formed by lecithin combined with ginsenosides in the liquid crystal emulsions of the present invention has excellent emulsifying ability and a wide range of applications. In particular, in Example 5, the amount of liquid oil used was higher, and the liquid crystal morphology in the resulting lecithin-containing liquid crystal emulsion was more uniform, resulting in a higher score.

[0100] While specific embodiments of the present invention have been described above, those skilled in the art should understand that these are merely illustrative examples, and the scope of protection of the present invention is defined by the appended claims. Those skilled in the art can make various changes or modifications to these embodiments without departing from the principles and essence of the present invention, but all such changes and modifications fall within the scope of protection of the present invention.

Claims

1. A liquid crystalline emulsion containing lecithin, characterized in that, Based on a total mass of 100 parts, it comprises the following components in parts by mass: 1-5 parts lecithin; Ginsenosides 0.5-5 parts; 3-15 parts of liquid oil; 1-5 parts of solid fats; Preservative 0.1-1 part; 1-10 parts of moisturizer; water; The mass ratio of the lecithin to the ginsenoside is (1.5-4):

1.

2. The liquid crystal emulsion containing lecithin according to claim 1, wherein, The mass ratio of the lecithin to the ginsenoside is (1.5-3):1; And / or, the liquid crystal emulsion containing lecithin does not contain surfactants other than lecithin; preferably, the surfactant is an emulsifier; the emulsifier preferably includes anionic emulsifiers, cationic emulsifiers, nonionic emulsifiers, and amphoteric emulsifiers, such as sodium dodecyl sulfate, sodium lauryl ether sulfate, potassium cetyl phosphate, sodium stearoyl glutamate, hexadecyl trimethylammonium chloride, glyceryl monostearate, polysorbate, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, fatty alcohol polyoxyethylene ether, polyethylene glycol fatty acid ester, ethoxylated castor oil, fatty acid monoglycerides, sucrose monostearate, cetearyl alcohol polyether, poloxamer, and polyglycerol emulsifiers; the polyglycerol emulsifier includes one or more of polyglycerol fatty acid esters, polyglycerol ethers, and polyglycerol condensed castor oil esters.

3. The lecithin-containing liquid crystal emulsion of claim 1, wherein The liquid crystal emulsion containing lecithin satisfies one or more of the following conditions (a)-(e): (a) The lecithin includes hydrogenated lecithin and / or egg yolk lecithin; (b) The liquid oil is one or more of vegetable oils, animal oils, and synthetic oils; wherein the vegetable oil preferably includes one or more of jojoba oil, macadamia nut oil, olive oil, sweet almond oil, coconut oil, castor oil, sunflower seed oil, and wheat germ oil; the animal oil preferably includes one or more of mink oil, shark liver oil, flounder oil, turtle oil, snake oil, white oil, and lanolin; the synthetic oil preferably includes one or more of polyoxyethylene-polyoxypropylene lanolin, squalane, polydimethylsiloxane, polymethylphenylsiloxane, cyclic methylsiloxane, caprylic / capric triglyceride, isopropyl palmitate, isohexadecane, isooctyl palmitate, and isooctyl isostearate. (c) The solid oil is one or more of fatty alcohols, steroids, glycerides and waxes; the fatty alcohols preferably include cetearyl alcohol and / or stearyl alcohol; the waxes include hydrogenated castor oil and / or pentaerythritol distearate; (d) The preservative is one or more of the following: parabens, benzyl alcohol, phenoxyethanol, 2-bromo-2-nitropropane-1,3-propanediol, hexamethylenetetramine derivatives, imidazolidinyl urea, dehydroacetic acid, sorbic acid, Kathon, glyceryl monolaurate, diazolidinyl urea, hydroxymethylhydantoin, and dimethyloldimethylhydantoin; (e) The moisturizer is a polyol moisturizer, preferably including one or more of glycerin, propylene glycol, 1,3-butanediol, dipropylene glycol, sorbitol, xylitol, erythritol and polyethylene glycol.

4. The lecithin-containing liquid crystal emulsion of claim 1, wherein, The liquid crystal emulsion containing lecithin also includes a thickener; The preferred mass fraction of the thickener is 0.1-2 parts. The thickener is preferably one or more of the following: carbomer, hydroxyethyl acrylate-sodium acryloyldimethyl taurate copolymer, sodium acrylate-sodium acryloyldimethyl taurate copolymer, and acrylic acid and its derivatives-C10-30 alkanol acrylate crosslinking polymers.

5. The liquid crystal emulsion containing lecithin as described in claim 1, characterized in that, The liquid crystal emulsion containing lecithin satisfies one or more of the following conditions (a)-(g): (a) The lecithin is present in 2-4 parts by mass; (b) The ginsenosides mentioned are present in 1-3 parts by mass; (c) The liquid oil has a mass fraction of 5-15 parts; (d) The solid oil has a mass fraction of 1-3 parts; (e) The preservative is present in parts by weight of 0.1-0.7 parts; (f) The humectant is present in 5-10 parts by weight; (g) The water is in the form of 65-80 parts by mass, preferably 66-78 parts by mass.

6. The liquid crystal emulsion containing lecithin as described in claim 5, characterized in that, The liquid crystal emulsion containing lecithin comprises 3 parts lecithin, 2 parts ginsenosides, 5 parts liquid oil, 2 parts solid oil, 0.5 parts preservative, 10 parts humectant, and 76.9 parts water. Alternatively, the liquid crystal emulsion containing lecithin may include 4 parts lecithin, 2 parts ginsenosides, 5 parts liquid oil, 2 parts solid oil, 0.5 parts preservative, 10 parts humectant, and 75.9 parts water. Alternatively, the liquid crystal emulsion containing lecithin may include 3 parts lecithin, 1 part ginsenoside, 5 parts liquid oil, 2 parts solid oil, 0.5 parts preservative, 10 parts humectant, and 77.9 parts water. Alternatively, the liquid crystal emulsion containing lecithin may include 3 parts lecithin, 2 parts ginsenosides, 10 parts liquid oil, 2 parts solid oil, 0.5 parts preservative, 10 parts humectant, and 71.9 parts water. Alternatively, the liquid crystal emulsion containing lecithin may include 3 parts lecithin, 2 parts ginsenosides, 15 parts liquid oil, 2 parts solid oil, 0.5 parts preservative, 10 parts humectant, and 66.9 parts water.

7. The liquid crystal emulsion containing lecithin as described in claim 6, characterized in that, The liquid crystal emulsion containing lecithin comprises 3 parts hydrogenated lecithin, 2 parts ginsenosides, 5 parts caprylic / capric triglyceride, 2 parts cetearyl alcohol, 0.5 parts phenoxyethanol, 10 parts glycerin, and 76.9 parts water. Alternatively, the liquid crystal emulsion containing lecithin comprises 4 parts hydrogenated lecithin, 2 parts ginsenosides, 5 parts caprylic / capric triglyceride, 2 parts cetearyl alcohol, 0.5 parts phenoxyethanol, 10 parts glycerin, and 75.9 parts water. Alternatively, the liquid crystal emulsion containing lecithin comprises 3 parts hydrogenated lecithin, 1 part ginsenoside, 5 parts caprylic / capric triglyceride, 2 parts cetearyl alcohol, 0.5 parts phenoxyethanol, 10 parts glycerin, and 77.9 parts water. Alternatively, the liquid crystal emulsion containing lecithin comprises 3 parts hydrogenated lecithin, 2 parts ginsenosides, 10 parts caprylic / capric triglyceride, 2 parts cetearyl alcohol, 0.5 parts phenoxyethanol, 10 parts glycerin, and 71.9 parts water. Alternatively, the liquid crystal emulsion containing lecithin may include 3 parts hydrogenated lecithin, 2 parts ginsenosides, 15 parts caprylic / capric triglyceride, 2 parts cetearyl alcohol, 0.5 parts phenoxyethanol, 10 parts glycerin, and 66.9 parts water.

8. A method for preparing a liquid crystal emulsion containing lecithin as described in any one of claims 1-7, characterized in that, It includes the following steps: The liquid crystal emulsion containing lecithin is obtained by mixing the components of the liquid crystal emulsion. Preferably, it includes the following steps: S1. Homogenize the oil phase mixture and the water to obtain a first homogenized mixture; wherein the oil phase mixture includes the lecithin, the ginsenosides, the liquid oil, the solid oil, and the humectant; the homogenization temperature is preferably 75-90℃, for example, 85℃; the homogenization speed is preferably 4000-8000 rpm, for example, 5000 rpm; S2. Homogenize the first homogenized mixture and the preservative; wherein the homogenization temperature is preferably 50-70℃, for example 60℃; and the homogenization speed is preferably 4000-8000 rpm, for example 5000 rpm.

9. The method for preparing a liquid crystal emulsion containing lecithin as described in claim 8, characterized in that, When the liquid crystal emulsion containing lecithin also includes a thickener, in step S2, before homogenizing the first homogenized mixture and the preservative, the first homogenized mixture and the thickener are first homogenized. The homogenization temperature is preferably 50-70℃, for example, 60℃; the homogenization speed is preferably 4000-8000 rpm, for example, 5000 rpm.

10. The application of a liquid crystal emulsion containing lecithin as described in any one of claims 1-7 in the cosmetics field.

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