Simple self-heating hyperthermic intraperitoneal chemotherapy device

Abstract

This invention discloses a simple self-heating intraperitoneal chemotherapy device, belonging to the field of medical equipment technology. It includes: a double-layered drug solution bag, a water bag, a mixing tank, and a circulation loop; the double-layered drug solution bag includes an inner drug solution containing cavity and an outer self-heating cavity. The inner cavity stores the chemotherapy drug solution, and the outer cavity heats the solution. The double-layered drug solution bag and water bag are connected to the inlet of the mixing tank. The circulation loop includes an input pipe, an output pipe, and a power pump. One end of the input pipe is connected to the outlet of the mixing tank, and the other end is connected to the abdominal cavity. One end of the output pipe is connected to the abdominal cavity, and the other end is connected to the return end of the mixing tank. The power pump is mounted on either the input or output pipe. This invention achieves self-heating of the drug solution through the outer self-heating cavity of the double-layered drug solution bag, eliminating the need for an external power source and large heating equipment. The overall structure is compact and small in size, easily movable to the bedside, and suitable for various usage environments such as primary healthcare institutions and emergency scenarios.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a simple self-heating intraperitoneal chemotherapy device. Background Technology

[0002] Hyperthermic intraperitoneal chemotherapy is an important means of treating malignant tumors in the peritoneum and preventing tumor metastasis in the peritoneum. Its core is to continuously circulate and infuse chemotherapy drugs heated to a specific temperature into the patient's peritoneum, using the thermal effect and the synergistic effect of chemotherapy drugs to kill tumor cells.

[0003] Currently, most intraperitoneal hyperthermic perfusion devices used in clinical practice are large-scale devices with the following shortcomings: First, they rely on external power sources and specialized heating equipment, making them bulky, inconvenient to move, and difficult to adapt to the needs of bedside treatment, primary healthcare institutions, or emergency scenarios; second, the temperature control methods are complex, often relying on the device's built-in heating module to directly heat the medication, which can easily lead to problems such as excessively high local temperatures damaging abdominal tissues or excessively low temperatures affecting treatment efficacy; third, the device components are mostly fixed connections, making disassembly inconvenient, resulting in high costs for single-use applications, while repeated use poses a risk of cross-infection; fourth, there is a lack of a comprehensive safety monitoring mechanism, making it difficult to provide timely warnings of abnormal pressure in the circulation loop, liquid leaks, etc., posing safety hazards.

[0004] Therefore, there is an urgent need for a simple, self-heating intraperitoneal chemotherapy device that is easy to construct, requires no external power source, has precise temperature control, and is safe and convenient to use, in order to overcome the aforementioned shortcomings of existing technologies. Summary of the Invention

[0005] The main objective of this invention is to provide a simple self-heating intraperitoneal chemotherapy device to solve the above-mentioned problems.

[0006] To achieve the above objectives, the present invention provides a simple self-heating intraperitoneal chemotherapy device, comprising: a double-layer drug bag, a water bag, a mixing box, and a circulation loop; The double-layered drug solution bag includes an inner drug solution containing cavity and an outer self-heating cavity. The inner drug solution containing cavity is used to store chemotherapy drugs, and the outer self-heating cavity is used to self-heat the chemotherapy drugs in the inner drug solution containing cavity. The double-layered drug solution bag is connected to the inlet of the mixing tank through a first connecting pipe, and the water bag is connected to the inlet of the mixing tank through a second connecting pipe. The first connecting pipe is equipped with a first valve, and the second connecting pipe is equipped with a second valve. The circulation loop includes an input pipe, an output pipe, and a power pump. One end of the input pipe is connected to the liquid outlet of the mixing tank, and the other end is used to connect to the human abdominal cavity input interface. One end of the output pipe is used to connect to the human abdominal cavity output interface, and the other end is connected to the liquid return end of the mixing tank. The power pump is installed on the input pipe or the output pipe.

[0007] Furthermore, the outer self-heating cavity includes one of an electric heating element, a chemical heating pack, or a phase change material, used to heat the inner liquid-containing cavity.

[0008] Furthermore, it also includes a temperature detection component, which includes a temperature sensor and a temperature display module. The temperature sensor is disposed in the mixing tank and the output pipe to detect the temperature of the mixture. The temperature display module is electrically connected to the temperature sensor to display the detected temperature value.

[0009] Furthermore, it also includes a controller, which is electrically connected to the temperature sensor, the first valve, and the second valve, respectively. The controller automatically adjusts the opening degree of the first valve and the second valve according to the temperature value detected by the temperature sensor.

[0010] Furthermore, the mixing chamber is equipped with a stirring device, which is a magnetic stirrer, a mechanical stirrer, or a baffle plate fixed to the inner wall of the mixing chamber.

[0011] Furthermore, the circulation loop also includes a filtration device disposed on the output pipe for filtering impurities or cell debris from the fluid returning from the peritoneal cavity.

[0012] Furthermore, it also includes a safety monitoring unit, which includes a pressure sensor, a leak detector, and an alarm module; the pressure sensor is installed on the input pipe and is used to detect the pressure in the circulation loop; the leak detector is used to detect liquid leaks at the pipe or connection; the alarm module is electrically connected to the pressure sensor and the leak detector and is used to issue an alarm when the pressure exceeds a threshold or a leak occurs.

[0013] Furthermore, the mixing box and the circulation loop are provided with an insulation layer, which is a pearl cotton layer, a rock wool layer, or a vacuum insulation layer.

[0014] Furthermore, the double-layer medicine bag and the water bag are disposable components, detachably connected to the mixing tank and the pipeline, and the mixing tank and the circulation loop are reusable or disposable.

[0015] The present invention has the following beneficial effects: This invention achieves self-heating of the medication through the outer self-heating chamber of the double-layered medication bag, eliminating the need for an external power source and large heating equipment. Its compact structure and small size allow for easy transport to the bedside, making it suitable for various environments such as primary healthcare institutions and emergency situations. The invention employs a temperature regulation method that mixes the self-heating medication with room-temperature water. Combined with a temperature sensor and controller for automatic valve opening adjustment, the temperature of the mixture can be stably controlled within the optimal treatment range, avoiding the impact of localized high or low temperatures on the treatment effect. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the simple self-heating intraperitoneal chemotherapy device of the present invention.

[0017] Among them, 1-double-layer medicine bag; 2-water bag; 3-mixing box; 4-inner medicine container cavity; 5-outer self-heating cavity; 6-first connecting pipe; 7-second connecting pipe; 8-input pipe; 9-output pipe. Detailed Implementation

[0018] To achieve the above objectives and effects, the technical means and structure adopted by the present invention will be described in detail with reference to the accompanying drawings, focusing on the features and functions of the preferred embodiments of the present invention.

[0019] like Figure 1 As shown, the present invention provides a simple self-heating intraperitoneal chemotherapy device, comprising: a double-layer drug bag 1, a water bag 2, a mixing box 3, and a circulation loop.

[0020] The double-layered drug solution bag 1 includes an inner drug solution containing cavity 4 and an outer self-heating cavity 5. The inner drug solution containing cavity 4 is used to store pre-prepared chemotherapy drugs, and the outer self-heating cavity 5 is used to self-heat the chemotherapy drugs in the inner drug solution containing cavity 4. The outer self-heating cavity 5 may be equipped with an electric heating element, a chemical heating pack, or a phase change material. The double-layered drug solution bag 1 is connected to the inlet end of the mixing tank 3 via a first connecting pipe 6, and a first valve is provided on the first connecting pipe 6.

[0021] Specifically, the electric heating element can be a silicone heating sheet, a polyimide heating film, or a carbon fiber heating cloth. These elements are thin, flexible, have high thermal efficiency, and provide uniform heating, allowing them to fit well onto the outer cavity surface of the double-layer medicine bag 1, forming a heating jacket. In use, the electric heating element is laid on the entire inner surface of the outer self-heating cavity 5 (i.e., in full contact with the outer wall of the inner medicine containing cavity 4), or arranged in a serpentine path to ensure uniform and thorough heating of the inner medicine.

[0022] The water bag 2 is used to store unheated saline or buffer solution, and is connected to the inlet end of the mixing tank 3 through the second connecting pipe 7. The second connecting pipe 7 is equipped with a second valve.

[0023] The mixing chamber 3 is used to receive and mix the heated medicine from the double-layer medicine bag 1 and the unheated liquid from the water bag 2. By mixing the hot and cold liquids, the temperature of the mixture can be quickly and accurately adjusted to the preset treatment temperature. A stirring device, such as a magnetic stirrer, a mechanical stirrer, or a baffle plate, can be installed inside the mixing chamber 3 to promote uniform mixing of the liquids. A drain port is also provided at the bottom of the mixing chamber 3.

[0024] The circulation loop includes an input pipe 8, an output pipe 9, and a power pump. One end of the input pipe 8 is connected to the outlet of the mixing tank 3, and the other end is connected to the input interface of the human abdominal cavity. One end of the output pipe 9 is connected to the output interface of the human abdominal cavity, and the other end is connected to the return end of the mixing tank 3. The power pump is installed on the input pipe 8 or the output pipe 9 to provide power for the circulation of liquid between the human abdominal cavity and the mixing tank 3. A filter device can also be installed on the output pipe 9 to filter impurities or cell debris in the liquid returning from the abdominal cavity.

[0025] In this embodiment, a temperature control unit for monitoring and regulating the temperature of the mixed liquid is also provided. It includes a temperature sensor and a temperature display module. The temperature sensor is installed in the mixing tank 3 and the output pipe 9 to detect the temperature of the mixed liquid and the return liquid in real time. The temperature display module displays the temperature value. Further, the unit may also include a controller. The controller automatically adjusts the opening degree of the first valve and the second valve based on the temperature value fed back by the temperature sensor, thereby controlling the mixing ratio of the hot and cold liquids and achieving precise closed-loop temperature control.

[0026] In this embodiment, a safety monitoring unit is also included, comprising a pressure sensor, a leak detector, and an alarm module. The pressure sensor is installed on the input pipe 8 to monitor the pressure within the circulation loop and prevent excessive intra-abdominal pressure; the leak detector is used to detect liquid leaks at pipe connections; the alarm module issues an audible and visual alarm when the pressure exceeds a safety threshold or a leak is detected, and can automatically stop the power pump via the controller to ensure treatment safety.

[0027] In this embodiment, to reduce heat loss, an insulation layer can be provided on the outside of the mixing box 3 and the circulation loop. The insulation layer can be made of materials such as pearl cotton, rock wool, or vacuum insulation.

[0028] In this embodiment, the double-layered medicine bag 1 and water bag 2 are disposable components, detachably connected to the mixing tank 3 and the pipeline, effectively avoiding cross-contamination. The mixing tank 3 and the circulation loop can be reusable or disposable.

[0029] In actual use, the controller opens the first and second valves to a certain degree according to the preset target temperature. The heated medicine solution is mixed with room temperature saline in the mixing tank 3, and the temperature is made uniform by a stirrer. The power pump starts and pumps the perfusion solution with the appropriate temperature in the mixing tank 3 into the patient's abdominal cavity through the inlet pipe 8. When the fluid in the abdominal cavity reaches a certain volume, the fluid flows back to the mixing tank 3 through the outlet pipe 9 under the drive of the pump, forming a circulation.

[0030] During this process, the controller continuously compares the real-time temperature detected by the temperature sensor with the target temperature. If the temperature is too high, the opening of the second valve (cold water) is increased, and the opening of the first valve (hot water) is decreased; if the temperature is too low, the opposite operation is performed. Through this closed-loop control, the infusion fluid temperature can be precisely stabilized within the range required for treatment. Simultaneously, the pressure sensor monitors the pipeline pressure in real time. If overpressure is detected or a leak is detected, the controller will immediately issue an alarm and stop the power pump to ensure treatment safety.

[0031] In another embodiment, the outer self-heating chamber 5 is internally sealed and divided into two or more compartments, each filled with different chemical reactants. The outer self-heating chamber 5 is provided with a pinchable isolation strip or a pull-ring type rupture structure. In use, the user squeezes the bag or pulls the pull ring to break the isolation between the different compartments, causing the originally separated chemical substances to mix and come into contact with each other, triggering an exothermic reaction.

[0032] Specifically, the outer self-heating chamber 5 is equipped with a buffer material (such as gel) to control the intensity of the reaction and the rate of heat release, so that the temperature is maintained within a relatively stable range and the sudden temperature rise is avoided from damaging the drug solution.

[0033] The outer self-heating chamber 5 is equipped with an insulation layer to reduce heat loss to the environment and ensure that heat is mainly transferred to the liquid medicine.

[0034] The above description is only a preferred embodiment of the present invention and not all embodiments. Anyone should know that structural changes made under the guidance of the present invention, and any technical solutions that are the same as or similar to the present invention, are within the protection scope of the present invention.

Claims

1. A simple self-heating intraperitoneal chemotherapy device, characterized in that, include: Double-layer medicine bag (1), water bag (2), mixing box (3) and circulation loop; The double-layer drug solution bag (1) includes an inner drug solution containing cavity (4) and an outer self-heating cavity (5). The inner drug solution containing cavity (4) is used to store chemotherapy drugs, and the outer self-heating cavity (5) is used to self-heat the chemotherapy drugs in the inner drug solution containing cavity (4). The double-layer drug solution bag (1) is connected to the inlet end of the mixing tank (3) through a first connecting pipe (6), and the water bag (2) is connected to the inlet end of the mixing tank (3) through a second connecting pipe (7). A first valve is provided on the first connecting pipe (6), and a second valve is provided on the second connecting pipe (7). The circulation loop includes an input pipe (8), an output pipe (9), and a power pump. One end of the input pipe (8) is connected to the liquid outlet of the mixing tank (3), and the other end is used to connect to the human abdominal cavity input interface. One end of the output pipe (9) is used to connect to the human abdominal cavity output interface, and the other end is connected to the liquid return end of the mixing tank (3). The power pump is installed on the input pipe (8) or the output pipe (9).

2. The simple self-heating intraperitoneal chemotherapy device as described in claim 1, characterized in that, The outer self-heating cavity (5) includes one of an electric heating element, a chemical heating pack or a phase change material, and is used to heat the inner liquid-containing cavity (4).

3. The simple self-heating intraperitoneal chemotherapy device as described in claim 2, characterized in that, It also includes a temperature detection component, which includes a temperature sensor and a temperature display module. The temperature sensor is disposed in the mixing tank (3) and the output tube (9) to detect the temperature of the mixture. The temperature display module is electrically connected to the temperature sensor to display the detected temperature value.

4. The simple self-heating intraperitoneal chemotherapy device as described in claim 3, characterized in that, It also includes a controller, which is electrically connected to the temperature sensor, the first valve and the second valve respectively. The controller automatically adjusts the opening degree of the first valve and the second valve according to the temperature value detected by the temperature sensor.

5. The simplified self-heating intraperitoneal chemotherapy device as described in claim 1, characterized in that, The mixing tank (3) is equipped with a stirring device, which is a magnetic stirrer, a mechanical stirrer or a baffle plate fixed to the inner wall of the mixing tank (3).

6. The simplified self-heating intraperitoneal chemotherapy device as described in claim 1, characterized in that, The circulation loop also includes a filtration device, which is disposed on the output pipe (9) for filtering impurities or cell debris in the fluid returning from the abdominal cavity.

7. The simplified self-heating intraperitoneal chemotherapy device as described in any one of claims 1-6, characterized in that, It also includes a safety monitoring unit, which includes a pressure sensor, a leak detector and an alarm module; the pressure sensor is installed on the input pipe (8) and is used to detect the pressure in the circulation loop; the leak detector is used to detect liquid leakage at the pipe or connection; the alarm module is electrically connected to the pressure sensor and the leak detector and is used to issue an alarm when the pressure exceeds the threshold or when there is a leak.

8. The simplified self-heating intraperitoneal chemotherapy device as described in claim 7, characterized in that, The mixing box (3) and the circulation loop are provided with an insulation layer, which is a pearl cotton layer, a rock wool layer or a vacuum insulation layer.

9. The simplified self-heating intraperitoneal chemotherapy device as described in claim 8, characterized in that, The double-layer medicine bag (1) and the water bag (2) are disposable components, detachably connected to the mixing tank (3) and the pipeline. The mixing tank (3) and the circulation loop are reusable or disposable.

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