A measurement method, system and related devices
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- HUAWEI TECH CO LTD
- Filing Date
- 2024-12-27
- Publication Date
- 2026-07-31
AI Technical Summary
Traditional electrocardiograms are large in size and are not convenient for users to carry with them. They cannot perform electrocardiogram monitoring anytime and anywhere.
An electronic device including a first electrode group and a second electrode group is designed. After the electrode group is implanted into subcutaneous tissue, physiological parameters are determined through the first electrode group, and the first electrode group and the second electrode group determine the electrocardiogram signal, so as to achieve simultaneous measurement of the electrocardiogram signal and other physiological parameters (such as blood sugar, blood ketone, blood lactate, uric acid).
It realizes the function of measuring electrocardiogram signals and multiple physiological parameters anytime and anywhere, and improves the efficiency of health monitoring.
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Figure CN122497461A_ABST
Abstract
Description
A measurement method, system and related device
[0001] This application claims priority to the Chinese patent application filed with the China Patent Office on December 29, 2023, with application number 202311865433.9 and application name “A measurement method, system and related devices”, the entire contents of which are incorporated by reference into this application. Technical Field
[0002] The present application relates to the field of electronic technology, and in particular to a measurement method, system and related devices. Background Art
[0003] With the continuous development of electronic technology, more and more electronic devices have health monitoring functions, allowing users to understand their health status in real time. ECG monitoring is one of the important components of health monitoring functions.
[0004] An electrocardiograph (ECG) is a medical device that monitors the heart's electrical current (ECG). During monitoring, the device uses multiple wet electrodes placed at different locations on the user's skin to obtain an ECG.
[0005] However, the electrocardiograph is large in size and inconvenient for users to carry around, so users cannot perform electrocardiogram monitoring anytime and anywhere. Summary of the Invention
[0006] The present application provides a measurement method, system and related devices, which realize the measurement of electrocardiogram signals anytime and anywhere, and can also measure one or more physiological parameters, thereby improving the efficiency of health monitoring.
[0007] In a first aspect, the present application provides a measurement method applied to a first electronic device, the first electronic device including a first electrode group and a second electrode group, the distance between the first electrode group and the second electrode group being greater than the first distance; when the first electrode group and the second electrode group are implanted in subcutaneous tissue, the method includes: determining a first physiological parameter through the first electrode group; determining an electrocardiogram signal through the first electrode group and the second electrode group.
[0008] In this way, the user's electrocardiogram signals can be measured anytime and anywhere, and physiological parameters such as blood sugar, blood ketones, blood lactate, uric acid, etc. can also be measured.
[0009] In one possible implementation, the first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode; the first pair of electrodes forms a loop with the first working electrode; determining the first physiological parameter through the first electrode group specifically includes: determining the first physiological parameter through the first working electrode and the first pair of electrodes; determining the electrocardiogram signal through the first electrode group and the second electrode group specifically includes: determining the electrocardiogram signal through the first working electrode and the second working electrode, or determining the electrocardiogram signal through the first pair of electrodes and the second working electrode.
[0010] In this way, the first electrode group can form a two-electrode system, through which the first physiological parameter can be measured. The first working electrode (or first pair of electrodes) in the first electrode group and any electrode in the second electrode group can serve as the left arm LA electrode and the right arm RA electrode, respectively, to measure the electrocardiogram signal.
[0011] In one possible implementation, the first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode; the first pair of electrodes and the first working electrode form a loop; the first working electrode or the first pair of electrodes is connected to the right leg drive circuit; determining the first physiological parameter through the first electrode group specifically includes: determining the first physiological parameter through the first working electrode and the first pair of electrodes; determining the electrocardiogram signal through the first electrode group and the second electrode group specifically includes: determining the electrocardiogram signal through the first working electrode, the first pair of electrodes, and the second working electrode.
[0012] The electrode connected to the right leg drive circuit can be used as the right leg drive RLD electrode. The right leg drive circuit can be used to offset the common mode signal.
[0013] In this way, the first electrode group can form a two-electrode system, through which the first physiological parameter can be measured. The first working electrode, the first pair electrode in the first electrode group, and any electrode in the second electrode group can respectively serve as the left arm LA electrode, the right leg driving RLD electrode, and the right arm RA electrode to measure ECG signals.
[0014] In one possible implementation, the first electrode group includes a first working electrode, a first reference electrode and a first pair of electrodes; the first reference electrode is used to control the voltage of the first working electrode, and the first pair of electrodes forms a loop with the first working electrode; determining the first physiological parameter through the first electrode group specifically includes: generating a first current through the first working electrode; and determining the first physiological parameter based on the first current.
[0015] In this way, the first electrode group can constitute a three-electrode system, through which the first current is generated and conducted.
[0016] In one possible implementation, the second electrode group includes a second working electrode, a second reference electrode and a second pair of electrodes; the second reference electrode is used to control the voltage of the second working electrode, and the second pair of electrodes is used to form a loop with the second working electrode; the method also includes: generating a second current through the second working electrode; and determining a second physiological parameter based on the second current.
[0017] In this way, the second electrode group can constitute a three-electrode system, through which the second current is generated and conducted.
[0018] In a possible implementation, determining the electrocardiogram signal through the first electrode group and the second electrode group specifically includes: determining the electrocardiogram signal through any electrode in the first electrode group and any electrode in the second electrode group.
[0019] The left arm electrode and the right arm electrode can be selected from one electrode in the first electrode group and one electrode in the second electrode group, respectively. In this way, the electrocardiogram signal can be measured through the left arm electrode and the right arm electrode.
[0020] In one possible implementation, determining the ECG signal through the first electrode group and the second electrode group specifically includes: determining the ECG signal through any two electrodes in the first electrode group and any one electrode in the second electrode group; or determining the ECG signal through any one electrode in the first electrode group and any two electrodes in the second electrode group.
[0021] The left arm electrode and the right arm electrode can be selected from one electrode in the first electrode group and one electrode in the second electrode group, respectively. The right leg drive electrode can be an electrode in the first electrode group or an electrode in the second electrode group. In this way, ECG signals can be measured using the left arm electrode, the right arm electrode, and the right leg drive electrode. The right leg drive electrode is used to cancel common-mode signals through the right leg drive circuit.
[0022] In this way, the electrochemical electrodes in the first electrode group can be used to measure both the first physiological parameter and the electrocardiogram signal.
[0023] In one possible implementation, the ECG signal is determined by any two electrodes in the first electrode group and any one electrode in the second electrode group, specifically including: when the first pair of electrodes is connected to the right leg drive circuit, the ECG signal is determined by the first pair of electrodes, the first working electrode and the second reference electrode.
[0024] In one possible implementation, the ECG signal is determined by any one electrode in the first electrode group and any two electrodes in the second electrode group, specifically including: when the second pair of electrodes is connected to the right leg drive circuit, the ECG signal is determined by the second pair of electrodes, the second working electrode and the first reference electrode.
[0025] It should be noted that the above two implementation methods are just two examples. In this application, other electrodes in the first electrode group and the second electrode group can also be selected to measure the electrocardiogram signal, and this application does not limit this.
[0026] In one possible implementation, the first electrode group also includes a first ECG electrode and a second ECG electrode, the second electrode group also includes a third ECG electrode, and the second ECG electrode is connected to the right leg drive circuit; determining the ECG signal through the first electrode group and the second electrode group specifically includes: determining the ECG signal through the first ECG electrode, the second ECG electrode, and the third ECG electrode.
[0027] In this way, ECG signals can be measured through the separately provided ECG electrodes.
[0028] In a possible implementation, the first electronic device further includes a first microneedle sensor and a second microneedle sensor, the first microneedle sensor includes a first electrode group, and the second microneedle sensor includes a second electrode group.
[0029] A microneedle sensor may refer to a sensor having a shape similar to a microneedle, and a plurality of electrodes may be provided inside the microneedle sensor.
[0030] In this way, the first electrode group and the second electrode group can be provided in the microneedle sensor.
[0031] In a possible implementation, the first electronic device further includes a first array sensor and a second array sensor, the first array sensor includes a first electrode group, and the second array sensor includes a second electrode group.
[0032] An array sensor may refer to a sensor comprising a plurality of electrodes arranged in an array. In a possible implementation, an array sensor may also be a plurality of electrodes arranged in an array.
[0033] In this way, the first electrode group and the second electrode group can be respectively arranged in the array sensor in the form of an array.
[0034] In a possible implementation, the first electronic device further includes a first microneedle sensor and a second array sensor, the first microneedle sensor includes a first electrode group, and the second array sensor includes a second electrode group.
[0035] In this way, the first electrode group can be provided in a microneedle sensor, and the second electrode group can be provided in an array sensor in an array form.
[0036] In one possible implementation, before determining the first physiological parameter through the first electrode group, the method also includes: determining that a first condition is satisfied, the first condition including any one or more of the following: receiving first information sent by the second electronic device, the first information is used to instruct the first electronic device to determine the first physiological parameter; detecting that the first electrode group and the second electrode group are implanted in subcutaneous tissue; detecting an abnormal electrocardiogram signal.
[0037] In this way, the first condition may be a trigger condition for measuring the first physiological parameter.
[0038] In one possible implementation, before determining the electrocardiogram signal through the first electrode group and the second electrode group, the method also includes: determining that a second condition is satisfied, the second condition including any one or more of the following: receiving second information sent by a second electronic device, the second information being used to instruct the first electronic device to determine the electrocardiogram signal; detecting that the first electrode group and the second electrode group are implanted in subcutaneous tissue; detecting that the first physiological parameter does not belong to the first interval.
[0039] In this way, the second condition may be a trigger condition for determining an electrocardiogram signal.
[0040] In a possible implementation, after determining the first physiological parameter through the first electrode group, the method further includes: outputting the first physiological parameter, or sending the first physiological parameter to a second electronic device.
[0041] In this way, the first physiological parameter can be output, or the first physiological parameter can be output through other electronic devices.
[0042] In a possible implementation, after the electrocardiogram signal is determined by the first electrode group and the second electrode group, the method further includes: outputting the electrocardiogram signal, or sending the electrocardiogram signal to a second electronic device.
[0043] In this way, the ECG signal can be output, or the ECG signal can be output through other electronic devices.
[0044] In a possible implementation, the first physiological parameter may include, but is not limited to, any one or more of the following: blood glucose, blood ketones, uric acid, blood lactate, etc.
[0045] In a second aspect, the present application provides an electronic device, which is a first electronic device, comprising a first electrode group and a second electrode group, wherein the distance between the first electrode group and the second electrode group is greater than the first distance; the first electrode group is used to determine a first physiological parameter when the first electrode group is implanted in subcutaneous tissue; the second electrode group is used to determine a second physiological parameter when the second electrode group is implanted in subcutaneous tissue; the first electrode group and the second electrode group are also used to determine an electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
[0046] In one possible implementation, the first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode and a second pair of electrodes; the first pair of electrodes forms a loop with the first working electrode, and the second pair of electrodes forms a loop with the second working electrode; the first electrode group is used to determine a first physiological parameter when the first electrode group is implanted in subcutaneous tissue, specifically including: the first working electrode is used to determine the first physiological parameter when the first working electrode is implanted in subcutaneous tissue; the second electrode group is used to determine a second physiological parameter when the second electrode group is implanted in subcutaneous tissue, specifically including: the second working electrode is used to determine the second physiological parameter when the second working electrode is implanted in subcutaneous tissue; the first electrode group and the second electrode group are also used to determine an electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue, specifically including: the first working electrode, the first pair of electrodes, and the second working electrode are also used to determine an electrocardiogram signal when the first working electrode, the first pair of electrodes, and the second working electrode are implanted in subcutaneous tissue.
[0047] In one possible implementation, the first electronic device also includes a microcontroller processing unit MCU; the first electrode group includes a first working electrode, a first reference electrode and a first pair of electrodes; the second electrode group includes a second working electrode, a second reference electrode and a second pair of electrodes; the first electrode group is used to determine a first physiological parameter when the first electrode group is implanted in subcutaneous tissue, specifically including: the first working electrode is used to generate a first current when the first working electrode is implanted in subcutaneous tissue; the first reference electrode is used to control the voltage of the first working electrode; the first pair of electrodes is used to form a loop with the first working electrode; the MCU is used to determine the first physiological parameter based on the first current; the second electrode group is used to determine a second physiological parameter when the second electrode group is implanted in subcutaneous tissue, specifically including: the second working electrode is used to generate a second current when the second working electrode is implanted in subcutaneous tissue; the second reference electrode is used to control the voltage of the second working electrode; the second pair of electrodes is used to form a loop with the second working electrode; the MCU is used to determine the second physiological parameter based on the second current.
[0048] In one possible implementation, the first electrode group and the second electrode group are also used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue, specifically including: any two electrodes in the first electrode group and any one electrode in the second electrode group are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue; or, any one electrode in the first electrode group and any two electrodes in the second electrode group are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
[0049] The left arm electrode and the right arm electrode can be selected from one electrode in the first electrode group and one electrode in the second electrode group, respectively. The right leg drive electrode can be an electrode in the first electrode group or an electrode in the second electrode group. In this way, ECG signals can be measured using the left arm electrode, the right arm electrode, and the right leg drive electrode. The right leg drive electrode is used to cancel common-mode signals through the right leg drive circuit.
[0050] In one possible implementation, any two electrodes in the first electrode group and any one electrode in the second electrode group are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue, specifically including: when the first pair of electrodes is connected to the right leg drive circuit, the first pair of electrodes, the first working electrode and the second reference electrode are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
[0051] In one possible implementation, any one electrode in the first electrode group and any two electrodes in the second electrode group are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue, specifically including: when the second pair of electrodes is connected to the right leg drive circuit, the second pair of electrodes, the second working electrode and the first reference electrode are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
[0052] It should be noted that the above two implementation methods are just two examples. In this application, other electrodes in the first electrode group and the second electrode group can also be selected to measure the electrocardiogram signal, and this application does not limit this.
[0053] In one possible implementation, the first electrode group also includes a first ECG electrode and a second ECG electrode, the second electrode group also includes a third ECG electrode, and the second ECG electrode is connected to the right leg drive circuit; the first electrode group and the second electrode group are also used to determine the ECG signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue, specifically including: the first ECG electrode, the second ECG electrode and the third ECG electrode are used to determine the ECG signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
[0054] In a possible implementation, the first electronic device further includes a first microneedle sensor and a second microneedle sensor, the first microneedle sensor includes a first electrode group, and the second microneedle sensor includes a second electrode group.
[0055] In a possible implementation, the first electronic device further includes a first array sensor and a second array sensor, the first array sensor includes a first electrode group, and the second array sensor includes a second electrode group.
[0056] In a possible implementation, the first electronic device further includes a first microneedle sensor and a second array sensor, the first microneedle sensor includes a first electrode group, and the second array sensor includes a second electrode group.
[0057] In a possible implementation, the first electronic device further includes a communication module; the communication module is used to send the first physiological parameter to the second electronic device; the communication module is also used to send an electrocardiogram signal to the second electronic device.
[0058] In a possible implementation, the first electronic device further includes an output module; the output module is configured to output the first physiological parameter; and the output module is further configured to output the electrocardiogram signal.
[0059] In a third aspect, the present application provides a measurement circuit, comprising a first electrode group, a second electrode group, a first electrochemical circuit module, a second electrochemical circuit module, an electrocardiogram circuit module and a microcontroller processing unit MCU; the first electrode group is connected to the first electrochemical circuit module, and the first electrode group is connected to the electrocardiogram circuit module; the second electrode group is connected to the second electrochemical circuit module, and the second electrode group is connected to the electrocardiogram circuit module; the MCU is connected to the first electrochemical circuit module, the second electrochemical circuit module and the electrocardiogram circuit module; the first electrode group is used to generate a first current signal; the first electrode group is also used to conduct the first current signal to the first electrochemical circuit module; the first electrochemical circuit module is used to determine the second current signal based on the first current signal; the first electrochemical circuit module is also used to The second current signal is transmitted to the MCU; the MCU is used to determine the first physiological parameter based on the second current signal; the second electrode group is used to generate a third current signal; the second electrode group is also used to transmit the third current signal to the second electrochemical circuit module; the second electrochemical circuit module is used to determine the fourth current signal based on the third current signal; the second electrochemical circuit module is also used to transmit the fourth current signal to the MCU; the MCU is used to determine the second physiological parameter based on the fourth current signal; the first electrode group and the second electrode group are used to obtain the first ECG signal; the first electrode group and the second electrode group are also used to transmit the first ECG signal to the ECG circuit module; the ECG circuit module is used to determine the second ECG signal based on the first ECG signal; the ECG circuit module is also used to transmit the second ECG signal to the MCU.
[0060] In one possible implementation, the first electrode group includes a first working electrode, a first reference electrode and a first counter electrode; the first electrochemical circuit module includes a first constant potential meter circuit and a first transimpedance circuit; the first constant potential meter circuit is used to control the voltage of the first working electrode and the first reference electrode; the first transimpedance circuit is used to amplify the first current signal; the first electrode group is connected to the first electrochemical circuit module, specifically including: the first working electrode, the first reference electrode and the first counter electrode are connected to the first constant potential meter circuit; the first working electrode is connected to the first transimpedance circuit.
[0061] In one possible implementation, the second electrode group includes a second working electrode, a second reference electrode and a second counter electrode; the second electrochemical circuit module includes a second constant potentiostat circuit and a second transimpedance circuit; the second constant potentiostat circuit is used to control the voltage of the second working electrode and the second reference electrode; the second transimpedance circuit is used to amplify the third current signal; the second electrode group is connected to the second electrochemical circuit module, specifically including: the second working electrode, the second reference electrode and the second counter electrode are connected to the second constant potentiostat circuit, and the second working electrode is connected to the second transimpedance circuit.
[0062] In one possible implementation, the ECG circuit module includes a right leg drive circuit, an amplifier circuit and a filter circuit, and the amplifier circuit is connected to the filter circuit; the right leg drive circuit is used to offset the common mode signal, the amplifier circuit is used to amplify the first ECG signal, and the filter circuit is used for filtering; the first electrode group is connected to the ECG circuit module, specifically including: the first working electrode is connected to the amplifier circuit, and the first pair of electrodes is connected to the right leg drive circuit; the second electrode group is connected to the ECG circuit module, specifically including: the second reference electrode is connected to the amplifier circuit module; the first electrode group and the second electrode group are used to obtain the first ECG signal, specifically including: the first working electrode and the second reference electrode The comparison electrode is used to obtain the first ECG signal; the first electrode group and the second electrode group are also used to transmit the first ECG signal to the ECG circuit module, specifically including: the first working electrode and the second reference electrode are used to transmit the first ECG signal to the amplification circuit; the ECG circuit module is used to determine the second ECG signal based on the first ECG signal, specifically including: the amplification circuit is used to amplify the first ECG signal and then transmit it to the filtering circuit; the filtering circuit is used to determine the second ECG signal based on the amplified first ECG signal; the ECG circuit module is also used to transmit the second ECG signal to the MCU, specifically including: the filtering circuit is also used to transmit the second ECG signal to the MCU.
[0063] In a possible implementation, the first electrode group also includes a first ECG electrode and a second ECG electrode, the second electrode group also includes a third ECG electrode, the ECG circuit module includes a right leg drive circuit, an amplifier circuit and a filter circuit, and the amplifier circuit is connected to the filter circuit; the right leg drive circuit is used to offset the common mode signal, the amplifier circuit is used to amplify the first ECG signal, and the filter circuit is used for filtering; the first electrode group is connected to the ECG circuit module, specifically including: the first ECG electrode is connected to the amplifier circuit, and the second ECG electrode is connected to the right leg drive circuit; the second electrode group is connected to the ECG circuit module, specifically including: the third ECG electrode The first electrode group and the second electrode group are connected to the amplification circuit module; the first ECG electrode and the third ECG electrode are used to transmit the ECG signal to the ECG circuit module, specifically including: the first ECG electrode and the third ECG electrode are used to transmit the ECG signal to the amplification circuit; the ECG circuit module is used to determine the second ECG signal based on the first ECG signal, specifically including: the amplification circuit is used to amplify the first ECG signal and then transmit it to the filtering circuit; the filtering circuit is used to determine the second ECG signal based on the amplified first ECG signal; the ECG circuit module is also used to transmit the second ECG signal to the MCU, specifically including: the filtering circuit is also used to transmit the second ECG signal to the MCU.
[0064] In a fourth aspect, the present application provides a measurement circuit, comprising a first electrode group, a second electrode group, a first switching switch, a first electrochemical circuit module, an electrocardiogram circuit module and a microcontroller processing unit MCU; the first switching switch comprises a first group of input ports, a second group of input ports and a first group of output ports, and the first switching switch is used to connect the first group of input ports or the second group of input ports; the first electrode group is connected to the first group of input ports, and the first electrode group is connected to the electrocardiogram circuit module; the second electrode group is connected to the second group of input ports, and the second electrode group is connected to the electrocardiogram circuit module; the first group of output ports is connected to the first electrochemical circuit module; the MCU is connected to the first electrochemical circuit module and the electrocardiogram circuit module; the first electrode group is used to generate a first current signal; the first electrode group is also used to conduct the first current signal to the first switching switch; the first switching switch is used to conduct the first current signal to the first electrochemical circuit module when the first group of input ports is connected; the first electrochemical circuit module is used The second current signal is determined based on the first current signal; the first electrochemical circuit module is also used to send the second current signal to the MCU; the MCU is used to determine the first physiological parameter based on the second current signal; the second electrode group is used to generate a third current signal; the second electrode group is also used to conduct the third current signal to the first switching switch; the first switching switch is used to conduct the third current signal to the first electrochemical circuit module when the second group of input ports is connected; the first electrochemical circuit module is also used to determine the fourth current signal based on the third current signal; the first electrochemical circuit module is also used to conduct the fourth current signal to the MCU; the MCU is used to determine the second physiological parameter based on the fourth current signal; the first electrode group and the second electrode group are used to obtain the first ECG signal; the first electrode group and the second electrode group are also used to conduct the first ECG signal to the ECG circuit module; the ECG circuit module is used to determine the second ECG signal based on the first ECG signal; the ECG circuit module is also used to conduct the second ECG signal to the MCU.
[0065] In one possible implementation, the first electrode group includes a first working electrode, a first reference electrode and a first counter electrode; the first group of input ports includes a first input port, a second input port and a third input port; the second electrode group includes a second working electrode, a second reference electrode and a second counter electrode; the second group of input ports includes a fourth input port, a fifth input port and a sixth input port; the first working electrode is connected to the first input port, the first reference electrode is connected to the second input port, and the first counter electrode is connected to the third input port; the second working electrode is connected to the fourth input port, the second reference electrode is connected to the fifth input port, and the second counter electrode is connected to the sixth input port.
[0066] In one possible implementation, the first group of output ports includes a first output port, a second output port, and a third output port; the first switching switch is used to connect the first group of input ports, specifically including: the first output port is used to connect the first input port, the second output port is used to connect the second input port, and the third output port is used to connect the third input port; the first switching switch is used to connect the second group of input ports, specifically including: the first output port is used to connect the fourth input port, the second output port is used to connect the fifth input port, and the third output port is used to connect the sixth input port.
[0067] In one possible implementation, the first electrochemical circuit module includes a first potentiostat circuit and a first transimpedance circuit; the first potentiostat circuit is used to control the voltage of the first working electrode and the first reference electrode; the first transimpedance circuit is used to amplify the first current signal; the first group of output ports is connected to the first electrochemical circuit module, specifically including: the first output port, the second output port, and the third output port are connected to the first potentiostat circuit; the first output port is connected to the first transimpedance circuit.
[0068] It can be understood that the measurement circuit provided in the fourth aspect can be combined with any possible implementation of the measurement circuit provided in the third aspect.
[0069] In a fifth aspect, the present application provides a measurement circuit, comprising a first electrode group, a second electrode group, a second switching switch, a third switching switch, a fourth switching switch, a first electrochemical circuit module, an electrocardiogram circuit module and a microcontroller processing unit MCU; the second switching switch comprises a third group of input ports, a fourth group of input ports and a second group of output ports, and the second switching switch is used to connect the third group of input ports or the fourth group of input ports; the first electrode group is connected to the third group of input ports, and the first electrode group is connected to the electrocardiogram circuit module; the second electrode group is connected to the fourth group of input ports, and the second electrode group is connected to the electrocardiogram circuit module; the second group of output ports is connected to the third group of input ports through the third switching switch. The switch and the fourth switch are connected to the first electrochemical circuit module, and the second output port is connected to the electrocardiogram circuit module through the third switch and the fourth switch; the third switch and the fourth switch are used to control the second group of output ports to connect to the first electrochemical circuit module or the electrocardiogram circuit module; the MCU is connected to the first electrochemical circuit module and the electrocardiogram circuit module; the first electrode group is used to generate a first current signal; the first electrode group is also used to conduct the first current signal to the second switch; the second switch is used when the second switch is connected to the third group of input ports, and the third switch and the fourth switch control the second group of output ports to connect to the first electrochemical circuit module, the first current signal is transmitted to the first electrochemical circuit module; the first electrochemical circuit module is used to determine the second current signal based on the first current signal; the first electrochemical circuit module is also used to send the second current signal to the MCU; the MCU is used to determine the first physiological parameter based on the second current signal; the second electrode group is used to generate a third current signal; the second electrode group is also used to transmit the third current signal to the first switch; the first switch is used to transmit the third current signal to the first electrochemical circuit module when the second switch is connected to the fourth group of input ports and the third switch and the fourth switch control the second group of output ports to connect to the first electrochemical circuit module. Circuit module; the first electrochemical circuit module is also used to determine the fourth current signal based on the third current signal; the first electrochemical circuit module is also used to transmit the fourth current signal to the MCU; the MCU is used to determine the second physiological parameter based on the fourth current signal; the first electrode group and the second electrode group are used to obtain the first ECG signal; the first electrode group and the second electrode group are also used to transmit the first ECG signal to the ECG circuit module when the third switching switch and the fourth switching switch control the second group of output ports to connect to the ECG circuit module; the ECG circuit module is used to determine the second ECG signal based on the first ECG signal; the ECG circuit module is also used to transmit the second ECG signal to the MCU.
[0070] It can be understood that the measurement circuit provided in the fifth aspect can be combined with any possible implementation of the measurement circuits provided in the third and fourth aspects.
[0071] In the sixth aspect, the present application provides a chip system, which is applied to a first electronic device, and the chip system includes: a processing circuit and an interface circuit, the interface circuit is used to receive code instructions and transmit them to the processing circuit, and the processing circuit is used to run the code instructions so that the chip system executes the measurement method in any possible implementation of any of the above aspects.
[0072] In a seventh aspect, an embodiment of the present application provides a readable storage medium, comprising instructions, which, when executed on a first electronic device, enable the first electronic device to execute the measurement method in any possible implementation of any of the above aspects.
[0073] In an eighth aspect, an embodiment of the present application provides a computer program product. When the computer program product is run on a first electronic device, the first electronic device executes the measurement method in any possible implementation of any of the above aspects.
[0074] The beneficial effects of the second to eighth aspects can refer to the beneficial effects of the first aspect mentioned above. BRIEF DESCRIPTION OF THE DRAWINGS
[0075] FIG1A is a schematic diagram of a scenario for measuring physiological parameters using a three-electrode system according to an embodiment of the present application;
[0076] FIG1B is a schematic diagram of the system architecture of a measurement system 10 provided in an embodiment of the present application;
[0077] FIG2A is a schematic diagram of the hardware structure of an electronic device 100 provided in an embodiment of the present application;
[0078] FIG2B is a schematic diagram of the hardware structure of an electronic device 200 provided in an embodiment of the present application;
[0079] FIG3A is a schematic diagram of a device configuration of an electronic device 200 provided in an embodiment of the present application;
[0080] FIG3B is a schematic diagram of the internal structure of an electronic device 200 provided in an embodiment of the present application;
[0081] FIG3C is a schematic diagram of the distribution of electrodes on a microneedle sensor 303 provided in an embodiment of the present application;
[0082] FIG3D is a schematic diagram of another electronic device 200 provided in an embodiment of the present application;
[0083] FIG3E is a schematic diagram of the internal structure of another electronic device 200 provided in an embodiment of the present application;
[0084] 4A-4B are schematic diagrams showing the connection relationship between two circuit modules and a processor provided in an embodiment of the present application;
[0085] 4C-4J are schematic diagrams of a set of measurement circuits provided in an embodiment of the present application;
[0086] FIG5A is a schematic diagram of a flow chart of a measurement method provided in an embodiment of the present application;
[0087] FIG5B is a schematic diagram of a waveform of an electrocardiogram signal provided in an embodiment of the present application;
[0088] FIG5C is an electrocardiogram provided in an embodiment of the present application;
[0089] FIG6 is a flow chart of another measurement method provided in an embodiment of the present application;
[0090] 7A-7F are schematic diagrams of output interfaces for a set of physiological parameters provided in an embodiment of the present application;
[0091] 7G-7J are schematic diagrams of output interfaces of a set of ECG signals provided in an embodiment of the present application;
[0092] 7K-7L are schematic diagrams of an interface for triggering ECG monitoring when a set of physiological parameters are abnormal, according to an embodiment of the present application;
[0093] 7M-7N are schematic diagrams of a set of interfaces for performing a micro-physical examination function according to an embodiment of the present application;
[0094] FIG8 is a schematic diagram of functional modules of an electronic device 200 provided in an embodiment of the present application;
[0095] FIG9 is a schematic diagram of functional modules of a measurement system 10 provided in an embodiment of the present application;
[0096] FIG10 is a schematic diagram of a physical device of an electronic device 300 provided in an embodiment of the present application;
[0097] FIG11 is a flow chart of a measurement method provided in an embodiment of the present application. DETAILED DESCRIPTION
[0098] The following is a clear and detailed description of the technical solutions in the embodiments of the present application in conjunction with the accompanying drawings. In the description of the embodiments of the present application, unless otherwise specified, " / " means or, for example, A / B can mean A or B; "and / or" in the text is only a description of the association relationship between related objects, indicating that there can be three relationships, for example, A and / or B can mean: A exists alone, A and B exist at the same time, and B exists alone. In addition, in the description of the embodiments of the present application, "multiple" means two or more than two.
[0099] In the following, the terms "first" and "second" are used for descriptive purposes only and should not be understood to imply or suggest relative importance or implicitly indicate the number of the technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the embodiments of this application, unless otherwise specified, "plurality" means two or more.
[0100] The term "user interface (UI)" in the following embodiments of this application refers to a medium interface for interaction and information exchange between an application or operating system and a user, which realizes the conversion between the internal form of information and the form acceptable to the user. The user interface is a source code written in a specific computer language such as Java and extensible markup language (XML). The interface source code is parsed and rendered on an electronic device and finally presented as content that the user can recognize. The commonly used form of user interface is graphical user interface (GUI), which refers to a user interface related to computer operations that is displayed in a graphical manner. It can be a visual interface element such as text, icons, buttons, menus, tabs, text boxes, dialog boxes, status bars, navigation bars, widgets, etc. displayed on the display screen of an electronic device.
[0101] The following introduces some terms involved in the embodiments of this application.
[0102] Electrocardiogram: Electrocardiogram (ECG) is a curve of biopotential changes generated when the heart beats. It is an important physiological indicator that characterizes the occurrence, propagation and recovery process of cardiac electrical excitation.
[0103] Electrocardiogram (ECG): During each cardiac cycle, the heart is excited successively by the pacemaker, atria, and ventricles, accompanied by changes in bioelectricity, which are called electrocardiogram (ECG). The heart pumps blood rhythmically, and its contraction and relaxation rhythm is controlled by the heart's electrical activity. Under normal circumstances, the sinoatrial node regularly emits impulses, which, through a specialized conduction system, generate electrical impulses throughout the myocardium. This electrical impulse generates an electric field that permeates the entire body. The resulting tiny currents are conducted through body tissues to different locations, causing different potentials to be generated in different parts of the body. Therefore, by placing electrodes at different locations on the body surface, the potential differences between different locations on the body surface can be measured, thereby determining the electrocardiogram (ECG).
[0104] Electrode Lead System: The electrode lead system indicates the number and arrangement of multiple electrodes used to measure ECG. Electrode lead systems may include, but are not limited to, any one or more of the following: the international standard 12-lead system, a bipolar lead system, etc.
[0105] International Standard 12-Lead System: In the international standard 12-lead system, ten electrodes are placed on the body surface: the left arm (LA), right arm (RA), left leg (LL), and right leg (RL). The remaining six electrodes are located on the chest. The electrode on the right leg serves as the reference electrode, while the remaining nine electrodes serve as ECG detection electrodes. They measure ECG signals (e.g., potential differences between different body parts) and generate an ECG based on these signals.
[0106] Bipolar lead system: The bipolar lead system can include three electrodes, a left arm (LA) electrode, a right arm (RA) electrode, and a right leg (RL) electrode. Generally, the left arm electrode is set on the left arm, the right arm electrode is set on the right arm, and the right leg electrode is set on the right leg. It should be noted that the above three electrodes can also be set at other locations on the human body. The bipolar lead system can obtain the ECG signal on the body surface by measuring the potential difference between the two limbs, and determine the electrocardiogram based on the measured ECG signal. Among them, the left arm electrode and the right arm electrode are used to obtain the ECG signal on the body surface (such as the potential difference between the left arm and the right arm, etc.), and the right leg electrode can be used as a reference electrode.
[0107] Common-mode interference: During ECG measurement, the right leg can be considered grounded. The LA and RA electrodes measure ground-based ECG signals. However, when the human body is grounded, there is ground impedance, which introduces common-mode interference and generates a common-mode signal. The right leg drive (RLD) circuit can cancel this common-mode signal. The RLD circuit can be connected to the RL electrode to eliminate this signal and improve measurement accuracy.
[0108] Right Leg Drive Electrode: A right leg drive (RLD) electrode refers to the RL electrode connected to the RLD circuit. The RLD electrode, LA electrode, and RA electrode can form a bipolar lead system for measuring ECG signals. In the embodiments of the present application, the electrodes used to measure ECG signals may also be referred to as ECG electrodes. When using a bipolar lead system to measure ECG signals, the ECG electrodes may include the LA electrode, the RA electrode, and the RLD electrode.
[0109] Blood sugar: Blood sugar refers to the level of glucose in the blood. Glucose is a vital component of the human body and a key source of energy. The human body requires a significant amount of sugar daily to fuel the normal functioning of various tissues and organs. Blood sugar must be maintained within a certain range to meet the needs of various organs and tissues. High blood sugar levels can easily lead to diabetes, while low blood sugar levels can lead to insufficient energy for organs, resulting in serious consequences.
[0110] Blood ketones: Blood ketones refer to the level of ketone bodies in the blood. Exercise metabolizes muscle and fat, producing ketone bodies that enter the bloodstream. A normal blood ketone level does not negatively impact the body. However, elevated blood ketone levels (e.g., above a certain threshold) can lead to acidosis.
[0111] Blood lactate: Blood lactate refers to the concentration of lactic acid in the blood. Blood lactate is an intermediate product of glucose metabolism in the body, primarily produced by red blood cells, striated muscle, and brain tissue. Its concentration depends primarily on the synthesis rate and metabolic rate of the liver and kidneys. Lactate monitoring measures blood lactate concentration and helps determine whether a user's liver and kidney function are normal.
[0112] Uric acid: Uric acid is the end product of purine metabolism. It is a trioxypurine whose alcohol form is weakly acidic. Uric acid is present in the human body and is excreted through urine. An imbalance between uric acid production and excretion can easily lead to elevated blood uric acid levels, which can cause disease. Uric acid is primarily produced in the liver, with most of it being excreted in urine via glomerular filtration. Therefore, uric acid monitoring can help determine the health of a user's liver and kidney function.
[0113] Electrochemical electrode: The electrochemical electrode reacts with a specific substance to form a current or voltage. In the embodiment of the present application, the electrochemical electrode can be used to measure one or more physiological parameters, such as blood glucose, blood ketones, uric acid, blood lactate, etc. Electrochemical electrodes can include the following according to different functions: working electrode, counter electrode and reference electrode. Multiple electrochemical electrodes with different functions can form an electrochemical system to measure physiological parameters. Common electrochemical systems include two-electrode system and three-electrode system.
[0114] Two-electrode system: A two-electrode system can include a working electrode and a counter electrode, or a working electrode and a reference electrode. In a two-electrode system, the working electrode can be used to generate the reaction under investigation, and the counter electrode (or reference electrode) can form a circuit with the working electrode and also control the voltage of the working electrode.
[0115] Three-electrode system: A three-electrode system can include a working electrode, a reference electrode, and a counter electrode. In this system, the working electrode can be used to initiate the reaction under investigation, the counter electrode can form a circuit with the working electrode, and the reference electrode can control the voltage of the working electrode. For a specific example of a three-electrode system, please refer to the embodiment shown in Figure 1A below.
[0116] Continuous glucose monitoring device: A continuous glucose monitoring (CGM) device is an electronic device used to measure blood sugar. The CGM device may include an electrochemical electrode, in which a glucose enzyme (such as glucose oxidase, etc.) may be provided. After the CGM device is implanted subcutaneously in the user, the glucose enzyme in the electrochemical electrode may react with the glucose in the tissue fluid to generate an electric current. The CGM device can measure the current generated by the reaction of the glucose enzyme with glucose, and determine the glucose concentration in the user's tissue fluid based on the magnitude of the current, and determine the glucose concentration in the user's blood based on the glucose concentration in the tissue fluid, that is, the user's blood sugar value.
[0117] Enzymes: Enzymes are proteins or ribonucleic acids (RNA) produced by living cells that are highly specific and catalytically efficient for their substrates. The ability of an enzyme to catalyze a chemical reaction is called enzyme activity (also known as enzyme activity). Enzyme activity is temperature-dependent. Different enzymes have different optimal temperatures. Enzymes are most active and catalytically efficient when their environment is at their optimal temperature.
[0118] For example, FIG1A shows a schematic diagram of a scenario for measuring physiological parameters through a three-electrode system provided in an embodiment of the present application.
[0119] As shown in Figure 1A, the three-electrode system can include a working electrode, a reference electrode, and a counter electrode. Among them, the working electrode (WE) is also called the research electrode, and the working electrode refers to the electrode used to generate the reaction under study. Taking the electrochemical electrode for measuring blood sugar as an example, the working electrode can have a substance that can react with glucose (such as glucose oxidase), and the working electrode can be used to react with glucose to generate a reaction current. The counter electrode (CE), also known as the auxiliary electrode, can form a loop with the working electrode to make the working electrode current flow smoothly to ensure that the reaction under study occurs on the working electrode. The reference electrode (RE) refers to an electrode with a known potential that is close to an ideal non-polarized electrode. There is basically no current passing through the reference electrode, which is used to control the voltage of the working electrode.
[0120] When the working electrode, reference electrode, and counter electrode are implanted in subcutaneous tissue, the working electrode reacts with the target substance (e.g., glucose, ketone bodies, uric acid, lactic acid, etc.), generating a reaction current. By measuring the magnitude of this reaction current, the value of the physiological parameter can be determined.
[0121] The following describes the system architecture of a measurement system 10 provided in an embodiment of the present application.
[0122] As shown in Figure 1B, the measurement system 10 may include an electronic device 100 and an electronic device 200. A communication connection may be established between the electronic device 100 and the electronic device 200. The above-mentioned communication connection may be a wired connection or a wireless connection. The wireless communication connection may be a wireless communication connection established by the electronic device 100 and the electronic device 200 using any one of wireless communication technologies such as wireless local area networks (WLAN) (such as wireless fidelity (Wi-Fi) networks), Bluetooth (BT), global navigation satellite system (GNSS), frequency modulation (FM), near field communication (NFC), infrared technology (IR), NearLink, intrabody communication (IBC), etc.
[0123] In some embodiments, the electronic device 100 may send information 3 to the electronic device 200 when it detects that the monitoring condition 3 is met, and the information 3 is used to request the electronic device 200 to send physiological data 1 to the electronic device 100, and the physiological data 1 is used to determine the user's physiological parameter 1 (such as blood sugar, blood ketones, uric acid, blood lactate, etc.). In some embodiments, the electronic device 100 may also send information 4 to the electronic device 200 when it detects that the monitoring condition 4 is met, and the information 4 is used to request the electronic device 200 to send the electrocardiogram signal to the electronic device 100. The specific content of monitoring condition 3 and monitoring condition 4 can refer to the relevant description in the embodiment shown in Figure 6 below, and will not be described in detail here. In some embodiments, the electronic device 100 may also send information 5 to the electronic device 200, and the information 5 is used to request the electronic device 200 to send the electrocardiogram signal and physiological data 1 to the electronic device 100.
[0124] The electronic device 100 can receive the physiological data sent by the electronic device 200 and determine and output the user's physiological parameters based on the physiological data. The electronic device 100 can also receive and output the electrocardiogram signal sent by the electronic device 200.
[0125] The electronic device 200 may include a plurality of electrochemical electrodes, which may react with specific chemical substances to generate a reaction current. The electronic device 200 may obtain physiological data of the user, and the physiological data may be used to determine any one or more physiological parameters such as blood sugar, blood ketones, uric acid, blood lactate, etc. The electronic device 200 may also obtain the user's electrocardiogram (ECG) signals through a plurality of ECG electrodes. It should be noted that, in some embodiments, the plurality of ECG electrodes may be a plurality of electrodes among the aforementioned plurality of electrochemical electrodes, or may be electrodes different from the aforementioned plurality of electrochemical electrodes. In other embodiments, one or more electrodes among the plurality of ECG electrodes may be the same as one or more electrochemical electrodes among the aforementioned plurality of electrochemical electrodes.
[0126] In some embodiments, the electronic device 200 may receive and, in response to information 3, transmit the user's physiological data to the electronic device 100. The electronic device 200 may also receive and, in response to information 4, transmit an electrocardiogram signal to the electronic device 100.
[0127] In other embodiments, the electronic device 200 may further determine and output the user's physiological parameter 1 (e.g., send the physiological parameter 1 to the electronic device 100) when detecting that monitoring condition 1 is satisfied. The electronic device 200 may further obtain and output the user's electrocardiogram signal (e.g., send the electrocardiogram signal to the electronic device 100) when detecting that monitoring condition 2 is satisfied. The specific contents of monitoring conditions 1 and 2 may also be referred to the relevant description in the embodiment shown in FIG. 5A below, and will not be described in detail here.
[0128] In the embodiments of the present application, electronic device 100 may be a wearable device such as a watch or bracelet, or may be a mobile phone, display screen, tablet computer, computer, etc. Electronic device 200 may be used to measure one or more physiological parameters and may also be used to measure electrocardiogram signals. This application does not limit the device types of electronic devices 100 and 200.
[0129] It is understandable that the measurement system 10 shown in FIG1B is only an example. In the embodiment of the present application, the measurement system 10 may also include electronic devices that are more, less, or have different device forms than those in the above embodiment, and the present application does not limit this.
[0130] The following describes the hardware structure of an electronic device 100 provided in an embodiment of the present application.
[0131] FIG2A shows a schematic diagram of the hardware structure of an electronic device 100 provided in an embodiment of the present application.
[0132] The electronic device 100 may be a mobile phone, a tablet computer, a desktop computer, a laptop computer, a handheld computer, a notebook computer, an ultra-mobile personal computer (UMPC), a netbook, a cellular phone, a personal digital assistant (PDA), an augmented reality (AR) device, a virtual reality (VR) device, an artificial intelligence (AI) device, a wearable device, an in-vehicle device, a smart home device, and / or a smart city device. The embodiments of the present application do not impose any particular restrictions on the specific type of the electronic device.
[0133] The electronic device 100 may include a processor 110, an internal memory 121, a charging management module 140, a power management module 141, a battery 142, a sensor module 180, and a display screen 194. Optionally, the electronic device 100 may further include any one or more of the following: a wireless communication module 160, an audio module 170, a button 190, a motor 191, an indicator 192, a photoplethysmography (PPG) module 195, and an airbag. The audio module 170 may include any one or more of the following: a speaker 170A, a receiver 170B, and a microphone 170C. The sensor module 180 may include a touch sensor 180K.
[0134] It should be understood that the structure illustrated in the embodiments of the present invention does not constitute a specific limitation on the electronic device 100. In other embodiments of the present application, the electronic device 100 may include more or fewer components than shown, or may combine or separate certain components, or arrange the components differently. The illustrated components may be implemented in hardware, software, or a combination of software and hardware.
[0135] The processor 110 may include one or more processing units. For example, the processor 110 may include an application processor (AP), a modem processor, a graphics processing unit (GPU), an image signal processor (ISP), a controller, a video codec, a digital signal processor (DSP), a baseband processor, and / or a neural-network processing unit (NPU). The different processing units may be independent devices or integrated into one or more processors.
[0136] The controller can generate operation control signals according to the instruction operation code and timing signal to complete the control of instruction fetching and execution.
[0137] Processor 110 may also include a memory for storing instructions and data. In some embodiments, the memory in processor 110 is a cache memory. This memory can store instructions or data that have just been used or are being recycled by processor 110. If processor 110 needs to use the same instruction or data again, it can directly access the memory. This avoids duplicate accesses, reduces processor 110 latency, and thus improves system efficiency.
[0138] In some embodiments, the processor 110 may include one or more interfaces. The interfaces may include an inter-integrated circuit (I2C) interface, an inter-integrated circuit sound (I2S) interface, a pulse code modulation (PCM) interface, a universal asynchronous receiver / transmitter (UART) interface, a mobile industry processor interface (MIPI), a general-purpose input / output (GPIO) interface, a subscriber identity module (SIM) interface, and / or a universal serial bus (USB) interface.
[0139] The charging management module 140 is configured to receive charging input from a charger. The charger can be either a wireless charger or a wired charger. In some wired charging embodiments, the charging management module 140 can receive charging input from the wired charger. In some wireless charging embodiments, the charging management module 140 can receive wireless charging input via the wireless charging coil of the electronic device 100. While charging the battery 142, the charging management module 140 can also provide power to the electronic device through the power management module 141.
[0140] The power management module 141 is used to connect the battery 142, the charging management module 140, and the processor 110. The power management module 141 receives input from the battery 142 and / or the charging management module 140 and provides power to the processor 110, the internal memory 121, the display 194, the wireless communication module 160, and the like. The power management module 141 can also be used to monitor parameters such as battery capacity, battery cycle count, and battery health status (leakage, impedance). In some other embodiments, the power management module 141 can also be provided in the processor 110. In other embodiments, the power management module 141 and the charging management module 140 can also be provided in the same device.
[0141] The wireless communication module 160 can provide wireless communication solutions applied to the electronic device 100, including wireless local area networks (WLAN) (such as wireless fidelity (Wi-Fi) networks), Bluetooth (BT), global navigation satellite system (GNSS), frequency modulation (FM), near field communication (NFC), infrared technology (IR), NearLink, intrabody communication (IBC), etc. Exemplarily, when two electronic devices communicate using a human body communication solution, the two electronic devices have at least one electrode in contact with the skin, and through the above-mentioned electrode in contact with the skin, the two electronic devices send and receive information to each other through the human body. The wireless communication module 160 can be one or more devices that integrate at least one communication processing module.
[0142] Electronic device 100 implements display functionality through a GPU, display screen 194, and an application processor. A GPU is a microprocessor for image processing that connects display screen 194 and the application processor. The GPU is used to perform mathematical and geometric calculations for graphics rendering. Processor 110 may include one or more GPUs that execute program instructions to generate or modify display information.
[0143] Display screen 194 is used to display images, videos, etc. Display screen 194 includes a display panel. The display panel can be a liquid crystal display (LCD). The display panel can also be made of an organic light-emitting diode (OLED), an active-matrix organic light-emitting diode or an active-matrix organic light-emitting diode (AMOLED), a flexible light-emitting diode (FLED), a MiniLED, a MicroLED, a Micro-oLed, a quantum dot light-emitting diode (QLED), etc. In some embodiments, electronic device 100 can include one or N display screens 194, where N is a positive integer greater than 1.
[0144] The internal memory 121 may include one or more random access memories (RAMs) and one or more non-volatile memories (NVMs). The RAM can be directly read and written by the processor 110 and can be used to store executable programs (e.g., machine instructions) of the operating system or other running programs, as well as user and application data. The NVM can also store executable programs and user and application data, and can be pre-loaded into the RAM for direct reading and writing by the processor 110.
[0145] The electronic device 100 can implement audio functions such as music playback and recording through the audio module 170, the speaker 170A, the receiver 170B, the microphone 170C, and the application processor.
[0146] The audio module 170 is used to convert digital audio information into analog audio signal output, and is also used to convert analog audio input into digital audio signals. The audio module 170 can also be used to encode and decode audio signals. In some embodiments, the audio module 170 can be provided in the processor 110, or some functional modules of the audio module 170 can be provided in the processor 110.
[0147] The speaker 170A, also called a "speaker", is used to convert audio electrical signals into sound signals. The electronic device 100 can listen to music or listen to hands-free calls through the speaker 170A.
[0148] The receiver 170B, also called a "handset", is used to convert audio electrical signals into sound signals. When the electronic device 100 receives a call or a voice message, the user can place the receiver 170B close to the ear to hear the voice.
[0149] Microphone 170C, also known as "microphone" or "microphone", is used to convert sound signals into electrical signals. When making a call or sending a voice message, the user can speak by putting their mouth close to the microphone 170C to input the sound signal into the microphone 170C. The electronic device 100 can be provided with at least one microphone 170C. In other embodiments, the electronic device 100 can be provided with two microphones 170C, which can not only collect sound signals but also realize noise reduction function. In other embodiments, the electronic device 100 can also be provided with three, four or more microphones 170C to collect sound signals, reduce noise, identify the source of sound, realize directional recording function, etc.
[0150] The touch sensor 180K is also called a "touch-sensitive device." The touch sensor 180K can be disposed on the display screen 194. The touch sensor 180K and the display screen 194 form a touch screen, also called a "touch screen." The touch sensor 180K is used to detect touch operations applied thereto or in the vicinity thereof. The touch sensor can transmit the detected touch operations to the application processor to determine the type of touch event. Visual output related to the touch operations can be provided via the display screen 194. In other embodiments, the touch sensor 180K can also be disposed on the surface of the electronic device 100, at a location different from that of the display screen 194.
[0151] The buttons 190 include a power button, a volume button, and the like. The buttons 190 may be mechanical buttons or touch buttons. The electronic device 100 may receive key inputs and generate key signal inputs related to user settings and function control of the electronic device 100.
[0152] Motor 191 can generate vibration prompts. Motor 191 can be used for incoming call vibration prompts, and can also be used for touch vibration feedback. For example, touch operations acting on different applications (such as taking pictures, audio playback, etc.) can correspond to different vibration feedback effects. For touch operations acting on different areas of the display screen 194, motor 191 can also correspond to different vibration feedback effects. Different application scenarios (for example: time reminders, receiving messages, alarm clocks, games, etc.) can also correspond to different vibration feedback effects. The touch vibration feedback effect can also support customization.
[0153] The indicator 192 may be an indicator light, which may be used to indicate the charging status, power level changes, messages, missed calls, notifications, etc.
[0154] The PPG module 195 is an optional component and may include a transmitter and a receiver. The transmitter may be configured to emit infrared light or green light, and the receiver may be configured to receive infrared light or green light reflected by biological tissue (e.g., skin, blood, etc.). In some embodiments, the PPG module 195 may measure any one or more of the following physiological information: blood oxygen concentration, heart rate, blood pressure, respiratory rate, etc.
[0155] In some embodiments, the sensor module 180 of the electronic device 100 may further include any one or more of the following sensors: an acceleration sensor, an air pressure sensor, a temperature sensor, a gyroscope sensor, etc. Among them:
[0156] The accelerometer can detect the magnitude of acceleration of the electronic device 100 in all directions (generally three axes). When the electronic device 100 is stationary, it can detect the magnitude and direction of gravity. It can also be used to identify the electronic device's posture, enabling applications such as switching between landscape and portrait modes and pedometers.
[0157] The air pressure sensor can be used to measure air pressure. In some embodiments, the air pressure sensor can also be used to measure water pressure.
[0158] The temperature sensor can be used to measure the user's body temperature or the temperature of the user's environment.
[0159] The gyroscope sensor can be used to determine the motion posture of the electronic device 100. In some embodiments, the angular velocity of the electronic device 100 around three axes (ie, x, y, and z axes) can be determined by the gyroscope sensor.
[0160] In some embodiments, the electronic device 100 may further include an air bag, which may be used to measure blood pressure.
[0161] FIG2B is a schematic diagram of the hardware structure of an electronic device 200 provided in an embodiment of the present application.
[0162] As shown in FIG2B , the electronic device 200 includes a processor 201 , a memory 202 , a sensor 203 , a wireless communication module 204 , a power module 205 , and an electrocardiogram module 206 .
[0163] It is understood that the structures illustrated in the embodiments of the present invention do not constitute specific limitations on the electronic device. In other embodiments of the present application, the electronic device may include more or fewer components than shown, or may combine or separate certain components, or arrange the components differently. The illustrated components may be implemented in hardware, software, or a combination of software and hardware.
[0164] Processor 201 may include one or more processing units, such as a modem processor, a digital signal processor, a controller, a baseband processor, and / or a neural network processor. The different processing units may be independent devices or integrated into one or more processors. Processor 201 may also be referred to as a microcontroller unit (MCU).
[0165] The controller can generate operation control signals according to the instruction operation code and timing signal to complete the control of instruction fetching and execution.
[0166] Processor 201 may also include a memory for storing instructions and data. In some embodiments, the memory in processor 201 is a cache memory. This memory can store instructions or data that have just been used or are being recycled by processor 201. If processor 201 needs to use the same instruction or data again, it can directly access the memory. This avoids duplicate accesses, reduces processor 201's latency, and thus improves system efficiency.
[0167] The wireless communication module 204 can provide wireless communication solutions for electronic devices, including wireless local area networks (WLAN) (such as wireless fidelity (Wi-Fi) networks), Bluetooth (BT), global navigation satellite system (GNSS), frequency modulation (FM), near field communication (NFC), infrared technology (IR), NearLink, intrabody communication (IBC), etc. Exemplarily, when two electronic devices communicate using a human body communication solution, the two electronic devices are equipped with at least one electrode in contact with the skin, and the two electronic devices send and receive information to each other through the human body through the above-mentioned electrode in contact with the skin. The wireless communication module 204 can be one or more devices that integrate at least one communication processing module. The wireless communication module 204 receives electromagnetic waves via an antenna, modulates the electromagnetic wave signal and filters it, and sends the processed signal to the processor 201. The wireless communication module 204 can also receive a signal to be sent from the processor 201, frequency-modulate the signal, amplify the signal, and convert the signal into an electromagnetic wave to be radiated through the antenna.
[0168] The memory 202 may include one or more random access memories and one or more non-volatile memories.
[0169] Non-volatile memory may include disk storage devices, flash memory.
[0170] The random access memory can be directly read and written by the processor 201, and can be used to store executable programs (such as machine instructions) of the operating system or other running programs, and can also be used to store user and application data.
[0171] The non-volatile memory may also store executable programs and user and application data, etc., which may be loaded into the random access memory in advance for direct reading and writing by the processor 201 .
[0172] The sensor 203 may further include, but is not limited to, any one or more of the following: a glucose detection sensor 2032 , a blood ketone detection sensor 2033 , a uric acid detection sensor 2034 , a lactic acid detection sensor 2035 , etc. Optionally, the sensor 203 may further include a temperature sensor 2031 .
[0173] The temperature sensor 2031 is used to detect temperature. In some embodiments, the electronic device 100 uses the temperature detected by the temperature sensor 2031 to determine the user's skin temperature and / or the ambient temperature.
[0174] In some embodiments, the electronic device 200 can measure the user's blood sugar. In a specific implementation, the electronic device 200 can measure the glucose concentration (tissue fluid sugar) in the tissue fluid through the glucose detection sensor 2032 and then calculate the glucose concentration (blood sugar) in the plasma (blood).
[0175] Glucose sensor 2032 is used to detect glucose concentration. In some embodiments, glucose sensor 2032 can determine glucose concentration by measuring oxygen consumption catalyzed by glucose oxidase or H2O2 generated by glucose oxidation in tissue fluid. In some embodiments, glucose sensor 2032 utilizes an electron mediator, such as nanomaterials, metallic osmium, ferrocene, or benzoquinones, to connect glucose oxidase to an electrode surface. This then transfers electrons through a series of redox reactions to determine glucose concentration.
[0176] When a user uses the electronic device 200 to measure blood sugar, the user can implant the electronic device 200 into the subcutaneous tissue. The electronic device 200 measures the glucose concentration in the tissue fluid through the electrodes of the glucose detection sensor 2032 to determine the user's blood sugar concentration.
[0177] In some embodiments, the electronic device 200 can measure the user's blood ketones. Specifically, the electronic device 200 can measure the ketone body concentration in the tissue fluid using the blood ketone detection sensor 2033 and then calculate the blood ketone concentration (blood ketones) in the plasma (blood). Alternatively, the electronic device 200 can also measure the blood ketone concentration in the blood.
[0178] The blood ketone detection sensor 2033 is used to detect blood ketone concentrations. When a user uses the electronic device 200 to measure blood ketones, the user can implant the electronic device 200 into subcutaneous tissue. The electronic device 200 then measures the blood ketone concentration in the tissue fluid using the electrodes of the blood ketone detection sensor 2033, thereby determining the user's blood ketone concentration. In other embodiments, the user can also drop a sample of blood into the electronic device 200, which then measures the blood ketone concentration using the electrodes of the blood ketone detection sensor 2033.
[0179] In some embodiments, the electronic device 200 can measure the uric acid level in the user's body. Specifically, the electronic device 200 can measure the ketone body concentration in the tissue fluid using the uric acid detection sensor 2034 and then calculate the uric acid concentration (uric acid) in the plasma (blood). Alternatively, the electronic device 200 can also measure the uric acid concentration in the blood or the uric acid concentration in the user's urine.
[0180] The uric acid detection sensor 2034 is used to detect the concentration of uric acid. When a user uses the electronic device 200 to measure uric acid, the user can implant the electronic device 200 into the subcutaneous tissue. The electronic device 200 measures the uric acid concentration in the tissue fluid through the electrodes of the uric acid detection sensor 2034, thereby determining the user's uric acid concentration. In other embodiments, the user can also drip sampled blood (or urine) into the electronic device 200, which then measures the uric acid concentration in the blood (or urine) through the electrodes of the uric acid detection sensor 2034.
[0181] Lactate detection sensor 2035 is used to detect blood lactate concentration. When a user uses electronic device 200 to measure blood lactate, the user can implant electronic device 200 into subcutaneous tissue. Electronic device 200 uses the electrodes of lactate detection sensor 2035 to measure the lactate concentration in the tissue fluid, thereby determining the user's blood lactate concentration. In other embodiments, the user can also drip sampled blood (or tissue fluid) into electronic device 200, which then uses the electrodes of lactate detection sensor 2035 to measure the lactate concentration in the blood (or tissue fluid).
[0182] In some embodiments, the electronic device 200 can send the collected physiological data to other devices, such as the electronic device 100, etc., through the wireless communication module 204.
[0183] The memory 202 may be used to store physiological data collected by the electronic device 200 , and optionally, may also be used to store the user's body temperature.
[0184] The power module 205 may include a battery 2051 and a power management module 2052. Optionally, the power module 205 may further include a charging management module 2053, etc.
[0185] The charging management module 2053 is configured to receive charging input from a charger. The charger can be either a wireless charger or a wired charger. In some wired charging embodiments, the charging management module 2053 can receive charging input from the wired charger. In some wireless charging embodiments, the charging management module 2053 can receive wireless charging input via the wireless charging coil of the electronic device 100. While charging the battery 2051, the charging management module 2053 can also provide power to the electronic device through the power management module 2052.
[0186] The power management module 2052 is used to connect the battery 2051, the charging management module 2053, and the processor 110. The power management module 2052 receives input from the battery 2051 and / or the charging management module 2053 and provides power to the processor 201, the memory 202, the wireless communication module 204, and the like. The power management module 2052 can also be used to monitor parameters such as battery capacity, battery cycle count, and battery health status (leakage, impedance). In some other embodiments, the power management module 2052 can also be provided in the processor 201. In other embodiments, the power management module 2052 and the charging management module 2053 can also be provided in the same device.
[0187] The ECG module 206 may have an ECG monitoring function for measuring the user's ECG signal and obtaining the user's ECG.
[0188] It should be understood that FIG2B is merely an illustrative illustration of the hardware structure of the electronic device 200. In other embodiments of the present application, the electronic device 200 may include more or fewer components, and the embodiments of the present application do not limit this.
[0189] An embodiment of the present application provides a measurement method, which is applied to a first electronic device (also referred to as electronic device 200), the first electronic device including a first electrode group (also referred to as electrode group 1) and a second electrode group (also referred to as electrode group 2), the distance between the first electrode group and the second electrode group being greater than a first distance; when the first electrode group and the second electrode group are implanted in subcutaneous tissue, the method includes: determining a first physiological parameter through the first electrode group; and determining an electrocardiogram signal through the first electrode group and the second electrode group.
[0190] In this way, the user's electrocardiogram signal can be obtained anytime and anywhere through the electronic device 200. Moreover, one or more other physiological parameters of the user (such as blood sugar, blood ketones, blood lactate, uric acid, etc.) can also be measured at the same time to improve health monitoring efficiency.
[0191] The following describes the device form and internal structure of the electronic device 200 provided in an embodiment of the present application.
[0192] FIG3A shows a schematic diagram of the device form of an electronic device 200 provided in an embodiment of the present application.
[0193] As shown in FIG3A , the electronic device 200 may include a bottom housing 301 and a plurality of microneedle sensors, such as microneedle sensor 303 and microneedle sensor 304 . Optionally, the electronic device 200 may further include a temperature measuring heat conducting column 302 .
[0194] In some embodiments, the bottom shell 301 can be connected to the temperature-measuring heat-conducting pillars 302, which can also be connected to the multiple microneedle sensors. In some embodiments, the temperature-measuring heat-conducting pillars 302 and the multiple microneedle sensors can be embedded in the bottom shell 301 or welded to the bottom shell 301. This application does not limit the specific connection method.
[0195] The temperature measuring thermal conductive column 302 can be used to measure the user's body temperature, such as measuring the user's body surface temperature or measuring the temperature of the user's subcutaneous tissue. In some embodiments, the temperature measuring thermal conductive column 302 can be in contact with the user's skin to measure the user's body surface temperature. In some embodiments, the temperature measuring thermal conductive column 302 can also be implanted in the subcutaneous tissue. In other embodiments, the temperature measuring thermal conductive column 302 can also be replaced with one or more temperature electrodes, which can also be set in the multiple microneedle sensors and implanted in the subcutaneous tissue.
[0196] The microneedle sensor can be used to be implanted in the subcutaneous tissue of the user. An electrode group can be provided in each microneedle sensor, and each electrode group can be used to measure one or more physiological parameters. Each electrode group can include two or more electrochemical electrodes. In some embodiments, the electrode group can include one or more working electrodes, one or more counter electrodes (or reference electrodes), and the two electrochemical electrodes can constitute one or more two-electrode systems, through which one or more physiological parameters can be measured. In other embodiments, the electrode group can include one or more working electrodes, one or more counter electrodes and one or more reference electrodes, and the three electrochemical electrodes can constitute one or more three-electrode systems, through which one or more physiological parameters can be measured. In other embodiments, optionally, one or more ECG electrodes can also be separately provided in the electrode group, such as one or more of the LA electrode, the RA electrode and the RLD electrode.
[0197] Exemplarily, the multiple microneedle sensors may include microneedle sensor 303 and microneedle sensor 304. Microneedle sensor 303 may include electrode group 1, and microneedle sensor 304 may include electrode group 2. Electrode group 1 may include at least one working electrode and at least one counter electrode. Optionally, electrode group 1 may also include one or more reference electrodes. Further optionally, electrode group 1 may also include one or more ECG electrodes. Similarly, electrode group 2 may include at least one working electrode and at least one counter electrode. Optionally, electrode group 2 may also include one or more reference electrodes. Further optionally, electrode group 2 may also include one or more ECG electrodes. Electrode group 1 may be used to measure physiological parameters of the user, and electrode group 2 may also be used to measure physiological parameters of the user. Physiological parameters may include, but are not limited to, any one or more of the following: blood glucose, blood ketones, uric acid, blood lactate, etc. The physiological parameters measured by electrode group 1 and electrode group 2 may be the same or different.
[0198] For example, electrode group 1 in microneedle sensor 303 can be used to measure a user's blood glucose, and electrode group 2 in microneedle sensor 304 can be used to measure a user's blood ketone levels. It should be understood that the embodiments herein are merely illustrative of how each microneedle sensor can be used to measure one or more physiological parameters. In the embodiments of the present application, microneedle sensors 303 and 304 can also be used to measure physiological parameters different from those in the above embodiments, and this application does not limit this.
[0199] It should be noted that the distance between the microneedle sensor 303 and the microneedle sensor 304 is greater than or equal to a preset distance (eg, 3 cm), so that the user's electrocardiogram signal can be obtained through the two microneedle sensors.
[0200] It can be understood that the embodiment shown in Figure 3A is only an example. In the embodiments of the present application, the electronic device 200 may also adopt a device form different from the above-mentioned embodiments, for example, including more microneedle sensors than the above-mentioned embodiments, or including more, fewer or different elements than the above-mentioned embodiments. The present application does not limit this.
[0201] FIG3B shows a schematic diagram of the internal structure of an electronic device 200 provided in an embodiment of the present application.
[0202] As shown in FIG3B , the electronic device 200 may include a microneedle sensor 303, a microneedle sensor 304, a printed circuit board (PCB) 305, and a battery 306. Optionally, the electronic device 200 may further include a temperature measuring heat conducting column 302.
[0203] The temperature measuring heat conducting column 302 can be connected to the PCB 305 to transmit the measured temperature to the PCB 305. For other details of the temperature measuring heat conducting column 302, please refer to the relevant description of the embodiment shown in FIG3A above, which will not be repeated here.
[0204] An electrode assembly 1 may be provided in the microneedle sensor 303. The electrode assembly 1 may include multiple electrochemical electrodes, such as a working electrode (WE) 3031 and a counter electrode (CE) 3033. Optionally, the electrode assembly 1 may also include a reference electrode (RE) 3032. The electrode assembly 1 is used to measure a physiological parameter 1 (e.g., blood glucose, blood ketones, uric acid, blood lactate, etc.). In the electrode assembly 1, the working electrode 3031 may react with a target substance 1 corresponding to the physiological parameter 1 to generate a reaction current. For example, if the physiological parameter 1 is blood glucose, the target substance 1 may be glucose; for another example, if the physiological parameter 1 is blood ketones, the target substance may be ketone bodies, etc. The reference electrode 3032 may be used to control the voltage of the working electrode 3031. The counter electrode 3033 may be used to form a circuit with the working electrode 3031 to ensure the generation and conduction of the reaction current. In some embodiments, the electrode assembly 1 may form a two-electrode system with the working electrode 3031 and the counter electrode 3033, and the two-electrode system may form a circuit to ensure the generation and conduction of the reaction current. In other embodiments, the electrode set 1 can be formed into a three-electrode system by using a working electrode 3031, a counter electrode 3033, and a reference electrode 3032. This three-electrode system forms a loop to ensure the generation and conduction of the reaction current. This two-electrode system and the three-electrode system can be used to measure physiological parameters 1.
[0205] An electrode group 2 may be provided in the microneedle sensor 304. The electrode group 2 may include a plurality of electrochemical electrodes, for example, a working electrode (WE) 3041 and a counter electrode (CE) 3043. Optionally, the electrode group 2 may further include a reference electrode (RE) 3042. The electrode group 2 is used to measure physiological parameters 2 (such as blood glucose, blood ketones, uric acid, blood lactate, etc.). It should be noted that physiological parameter 1 may be different from physiological parameter 2. In some embodiments, physiological parameter 1 may also be the same as physiological parameter 2. The functions of each electrode in the electrode group 2 may be analogously referred to the functions of each electrode in the above-mentioned electrode group 1. The electrode group 2 may also constitute a two-electrode system or a three-electrode system based on the type and number of electrochemical electrodes, and measure physiological parameter 2 through the two-electrode system or the three-electrode system.
[0206] Electrode group 1 and electrode group 2 can also be used to measure the user's electrocardiogram signal.
[0207] In some embodiments, the electrochemical electrodes in electrode group 1 and the electrochemical electrodes in electrode group 2 can be used as ECG electrodes to measure ECG signals. Any electrode in electrode group 1 and any electrode in electrode group 2 can be used as LA electrode and RA electrode respectively, and the RLD electrode can be an electrode in electrode group 1 or an electrode in electrode group 2, and the RLD electrode is connected to a right leg drive circuit, which is used to offset the common mode signal. For example, RE3032 in microneedle sensor 303 can be used as an LA electrode, WE3041 in microneedle sensor 304 can be used as an RA electrode, and CE3043 can be used as an RLD electrode. It can be understood that the embodiment here is only an example. In the embodiment of the present application, other electrodes in electrode group 1 and electrode group 2 can also be selected as ECG electrodes to measure ECG signals, and the present application does not limit this. In the above case, some of the electrochemical electrodes in electrode group 1 and electrode group 2 can measure both the user's physiological parameters and the user's ECG signals.
[0208] In other embodiments, separate ECG electrodes may be provided in electrode groups 1 and 2 for measuring ECG signals. The LA and RA electrodes may be provided in different electrode groups, while the RLD electrode may be provided in either electrode group. In this case, ECG signals can be measured using the ECG electrodes, and these electrodes are used solely for measuring ECG signals.
[0209] In other embodiments, separate ECG electrodes may be provided in electrode group 1 and electrode group 2, and at the same time, some of the electrochemical electrodes in electrode group 1 and electrode group 2 may also be used as ECG electrodes. For example, an RLD electrode may be provided in electrode group 1, and at the same time, one of the electrochemical electrodes in electrode group 1 and electrode group 2 may be selected as the LA electrode and the RA electrode, respectively. In this way, ECG signals may also be measured by the RLD electrode and multiple electrochemical electrodes. It is understandable that this is only an exemplary explanation, and some of the ECG electrodes may use the electrochemical electrodes in electrode group 1 and electrode group 2. In the embodiments of the present application, more, fewer, or different ECG electrodes than those in the above embodiments may be provided, or other electrochemical electrodes may be used as ECG electrodes to measure ECG signals, and the present application does not limit this.
[0210] PCB 305 can obtain the user's electrocardiogram (ECG) signals via microneedle sensors 303 and 304. It can also obtain the user's physiological data 1 via microneedle sensor 303. Physiological data 1 is used to determine physiological parameter 1. PCB 305 can also obtain the user's physiological data 2 via microneedle sensor 304. Physiological data 2 is used to determine physiological parameter 2. PCB 305 may include multiple circuit modules. The internal circuit structures of these multiple circuit modules and the connections between these modules can be found in the embodiments illustrated in Figures 4A-4J below and are not described in detail here.
[0211] The battery 306 can be used to power multiple modules in the electronic device 200, such as the PCB 305. In some embodiments, the battery 306 can be a lithium battery. In other embodiments, the battery 306 can also be a battery made of other materials, which is not limited in this application.
[0212] It is understandable that the embodiment shown in FIG3B is merely an example. In some embodiments, the electronic device 200 may further include more microneedle sensors than in the above embodiment, and the microneedle sensors may also include more or fewer electrochemical electrodes than in the above embodiment. This application does not limit this.
[0213] FIG3C shows a schematic diagram of the distribution of electrodes on a microneedle sensor 303 provided in an embodiment of the present application.
[0214] As shown in Figure 3C, microneedle sensor 303 may include an upper skin portion and a lower skin portion, wherein the lower skin portion is implanted in the subcutaneous tissue of the user, and the upper skin portion is connected to PCB 305. For example, microneedle sensor 303 may be an irregularly shaped sheet having two opposing surfaces, namely, surface A and surface B.
[0215] The microneedle sensor 303 may be provided with an electrode group 1. For a detailed description of the electrode group 1, reference may be made to the relevant contents in the embodiment shown in FIG. 3A-FIG 3B above. Exemplarily, the electrode group 1 may include a working electrode 3031, a reference electrode 3032, and a counter electrode 3033. In some embodiments, all electrochemical electrodes in the electrode group 1 may be provided on the A surface of the microneedle sensor 303. Each electrochemical electrode may include a measuring end, a conducting end, and a wire for connecting the measuring end and the conducting end. The measuring ends of the one or more electrochemical electrodes are all provided on the A surface of the subcutaneous portion, and the conducting ends of the one or more electrochemical electrodes are all provided on the A surface of the supracutaneous portion.
[0216] It should be understood that the embodiment shown in FIG3A is merely an example of how all electrodes on the microneedle sensor 303 can be arranged on the same surface of the microneedle sensor 303. In other embodiments, the electrodes on the microneedle sensor 303 can also be arranged on different surfaces of the microneedle sensor 303, for example, the working electrode 3031 can be arranged on surface A, and the reference electrode 3032 and the counter electrode 3033 can be arranged on surface B. This application does not limit this. Furthermore, in other embodiments, the microneedle sensor 303 can also adopt a form different from that shown in FIG3C, such as a needle, cylinder, triangular prism, polyhedron, etc. This application does not limit the specific form of the microneedle sensor 303.
[0217] In this way, when the subcutaneous portion of the microneedle sensor 303 is implanted in the subcutaneous tissue of the user, the microneedle sensor 303 can obtain the user's physiological data 1 through the one or more electrochemical electrodes.
[0218] In other embodiments, the microneedle sensor 303 may also include multiple working electrodes. In one possible implementation, two or more working electrodes may share the same reference electrode and / or counter electrode to form different three-electrode systems (or two-electrode systems) to measure the same or different physiological parameters, such as blood glucose and blood ketones. In another possible implementation, the microneedle sensor 303 may also include multiple reference electrodes and / or counter electrodes. These multiple working electrodes can form different three-electrode systems (or two-electrode systems) with different reference electrodes and / or counter electrodes to measure the same or different physiological parameters.
[0219] It should be noted that the electrode distribution on the microneedle sensor 304 can also refer to the electrode distribution of the microneedle sensor 303 shown in Figure 3C above. In addition, if the electronic device 200 also includes other microneedle sensors, the electrode distribution on the microneedle sensor can also refer to the relevant description in the embodiment shown in Figure 3C above, and this application will not go into details about this.
[0220] FIG3D shows a schematic diagram of the device form of another electronic device 200 provided in an embodiment of the present application.
[0221] As shown in Figure 3D, the electronic device 200 may include a bottom shell 301 and a plurality of array sensors, each array sensor may include an electrode group, and the specific content of the electrode group may refer to the relevant description in the embodiment shown in Figure 3A above, which will not be repeated here. Optionally, the electronic device 200 may further include a temperature measuring heat conductive column 302. The specific content of the temperature measuring heat conductive column 302 may refer to the relevant description in the embodiment shown in Figures 3A-3B above, which will not be repeated here. In some embodiments, the multiple array sensors may be provided on the bottom shell 301, and optionally, a temperature measuring heat conductive column 302 may also be provided. In an embodiment of the present application, a sensor may refer to an element for obtaining a specific signal (such as a current signal, a voltage signal, a light signal, etc.). In some embodiments, an array sensor may also refer to a plurality of electrodes arranged in an array.
[0222] For example, the plurality of array sensors may include array sensor 307 and array sensor 308. Array sensor 307 may include electrode group 1, and array sensor 308 may include electrode group 2.
[0223] Electrode set 1 may include multiple electrochemical electrodes, such as a working electrode group 3073 and a counter electrode group 3075, and optionally, a reference electrode group 3074. Furthermore, it may optionally include one or more ECG electrodes, such as a right leg drive (RLD) electrode 3072 and a right arm (RA) electrode 3071. Each electrode group may include one or more electrochemical electrodes of the same type. In some embodiments, the working electrode group 3073 and the counter electrode group 3075 in electrode set 1 may constitute one or more two-electrode systems, each of which may form a loop to ensure the generation and conduction of a reaction current. Through this two-electrode system, electrode set 1 may measure one or more physiological parameters. In other embodiments, the working electrode group 3073, the reference electrode group 3074, and the counter electrode group 3075 in electrode set 1 may constitute one or more three-electrode systems, each of which may form a loop to ensure the generation and conduction of a reaction current. It should be noted that, in some embodiments, multiple two-electrode systems (or three-electrode systems) may share a counter electrode and / or a reference electrode. The electrode set 1 can measure the physiological parameter 1 through a two-electrode system and / or a three-electrode system.
[0224] Electrode set 2 may include multiple electrochemical electrodes, such as a working electrode group 3082 and a counter electrode group 3084, and optionally, a reference electrode group 3083. Furthermore, it may optionally include one or more ECG electrodes, such as a left arm (LA) electrode 3081. Each electrode group may include one or more electrochemical electrodes of the same type. In some embodiments, the working electrode group 3082 and the counter electrode group 3084 in electrode set 2 may form one or more two-electrode systems, each of which may form a loop to ensure the generation and conduction of a reaction current. Through this two-electrode system, electrode set 2 may measure one or more physiological parameters. In other embodiments, the working electrode group 3082, the reference electrode group 3083, and the counter electrode group 3084 in electrode set 2 may form one or more three-electrode systems, each of which may form a loop to ensure the generation and conduction of a reaction current. It should be noted that, in some embodiments, multiple two-electrode systems (or three-electrode systems) may share a counter electrode and / or a reference electrode. Through the two-electrode system and / or the three-electrode system, electrode set 2 may measure physiological parameter 2.
[0225] It can be understood that the above embodiment is only an example of how electrode group 1 and electrode group 2 can include one or more ECG electrodes. In the embodiment of the present application, it is only necessary to ensure that the LA electrode and the RA electrode are located in different electrode groups, and the RLD electrode can be located in any electrode group. The present application does not limit the specific correspondence between the ECG electrodes and the electrode groups.
[0226] In other embodiments, separate ECG electrodes may be provided in electrode group 1 and electrode group 2, such as a left arm (LA) electrode 3081, a right leg drive (RLD) electrode 3072, and a right arm (RA) electrode 3071. In this case, ECG signals can be measured via the ECG electrodes, and the ECG electrodes are only used to measure ECG signals.
[0227] In some embodiments, the electrochemical electrodes in electrode group 1 and the electrochemical electrodes in electrode group 2 can be used as ECG electrodes to measure ECG signals. Any electrode in electrode group 1 and any electrode in electrode group 2 can be used as LA electrodes and RA electrodes respectively, and the RLD electrode can be an electrode in electrode group 1 or an electrode in electrode group 2, and the RLD electrode is connected to a right leg drive circuit, which is used to offset the common mode signal. For example, one or more reference electrodes in the reference electrode group 3074 in electrode group 1 can be used as LA electrodes, one or more working electrodes in the working electrode group 3082 in electrode group 2 can be used as RA electrodes, and one or more counter electrodes in the counter electrode group 3084 can be used as RLD electrodes. It can be understood that the embodiment here is only an example. In the embodiment of the present application, other electrodes in electrode group 1 and electrode group 2 can also be selected as ECG electrodes to measure ECG signals, and the present application does not limit this. In the above case, some of the electrochemical electrodes in electrode group 1 and electrode group 2 can measure both the user's physiological parameters and the user's ECG signals.
[0228] In other embodiments, separate ECG electrodes may be provided in electrode group 1 and electrode group 2, and at the same time, some of the electrochemical electrodes in electrode group 1 and electrode group 2 may also be used as ECG electrodes. For example, an RLD electrode may be provided in electrode group 1, and at the same time, one of the electrochemical electrodes in electrode group 1 and electrode group 2 may be selected as the LA electrode and the RA electrode, respectively. In this way, ECG signals may also be measured by the RLD electrode and multiple electrochemical electrodes. It will be understood that this is merely an illustrative description, and some of the ECG electrodes may use the electrochemical electrodes in electrode group 1 and electrode group 2. In the embodiments of the present application, other electrochemical electrodes may also be used as ECG electrodes to measure ECG signals, and the present application does not limit this.
[0229] The specific functions of the working electrode, reference electrode and counter electrode in the above-mentioned array sensor 307 and array sensor 308 can be analogously referred to the functional description of each electrode in the embodiment shown in Figure 3B above, and will not be repeated here.
[0230] It should be noted that the distance between the array sensor 307 and the array sensor 308 is greater than or equal to a preset distance (eg, 3 cm), so that the user's electrocardiogram signal can be obtained through the two array sensors.
[0231] It can be understood that the embodiment shown in Figure 3D is only an example. In the embodiments of the present application, the electronic device 200 may also adopt a device form different from the above-mentioned embodiments, for example, including more array sensors than the above-mentioned embodiments, or including more, fewer or different electrodes (including ECG electrodes and electrochemical electrodes) in the array sensor than the above-mentioned embodiments, or including more, fewer or different elements than the above-mentioned embodiments. The present application does not limit this.
[0232] It should be noted that the embodiments shown in Figures 3A and 3D above are just two examples. In the embodiments of the present application, the electronic device 200 may also include one or more array sensors and one or more microneedle sensors. The microneedle sensor may include multiple electrodes, and the array sensor may also include multiple electrodes. The electronic device 200 may also determine one physiological parameter through an array sensor and another physiological parameter through a microneedle sensor. It may also obtain electrocardiogram signals through microneedle sensors and array sensors. This application does not limit this.
[0233] FIG3E shows a schematic diagram of the internal structure of an electronic device 200 provided in an embodiment of the present application.
[0234] As shown in FIG3E , the electronic device 200 may include an array sensor 307, an array sensor 308, a printed circuit board (PCB) 305, and a battery 306. Optionally, the electronic device 200 may further include a temperature measuring heat conducting column 302.
[0235] The temperature measuring heat conducting column 302 can be connected to the PCB 305 to transmit the measured temperature to the PCB 305. For other details of the temperature measuring heat conducting column 302, please refer to the relevant description of the embodiment shown in FIG3D above, which will not be repeated here.
[0236] The electrode configuration of array sensor 307 (i.e., the electrode configuration of electrode group 1) and the electrode configuration of array sensor 308 (i.e., the electrode configuration of electrode group 2) can be referred to the relevant description of the embodiment shown in FIG. 3D above and will not be repeated here. It should be noted that array sensor 307 and array sensor 308 can be disposed on PCB 305 or connected to the PCB.
[0237] In some embodiments, PCB305 can acquire the user's electrocardiogram (ECG) signals via array sensors 307 and 308, and can also acquire the user's physiological data 1 via array sensor 307. Physiological data 1 is used to determine physiological parameter 1. PCB305 can also acquire the user's physiological data 2 via array sensor 308. Physiological data 2 is used to determine physiological parameter 2. PCB305 may include multiple circuit modules. The circuit configuration within these multiple circuit modules and the connection relationships between these circuit modules can be referenced in the embodiments illustrated in Figures 4A-4J below and are not described in detail here. It should be noted that physiological parameter 1 may include one or more physiological parameters. In some embodiments, the multiple working electrodes in array sensor 307 may be used to acquire physiological data of different physiological parameters. In this case, multiple different physiological parameters, such as blood glucose and blood ketones, can be determined based on physiological data 1, but this is not limited in this application. It is understood that physiological parameter 2 may also include one or more physiological parameters.
[0238] The battery 306 can be used to power multiple modules in the electronic device 200, such as the PCB 305. In some embodiments, the battery 306 can be a lithium battery. In other embodiments, the battery 306 can also be a battery made of other materials, which is not limited in this application.
[0239] It will be understood that the embodiment shown in FIG3E is merely an example. In some embodiments, the electronic device 200 may further include more array sensors than in the above embodiment, and the array sensor 307 and / or the array sensor 308 may also include more or fewer electrodes (including ECG electrodes and electrochemical electrodes) than in the above embodiment. This application does not impose any limitations thereon.
[0240] The following describes the connection relationship between the various circuit modules in the PCB 305 provided in the embodiment of the present application.
[0241] FIG4A shows a schematic diagram of the connection relationship between various circuit modules in a PCB 305 provided in an embodiment of the present application.
[0242] As shown in FIG4A , PCB 305 may include a microcontroller unit (MCU) 401, an analog-to-digital converter (ADC) 402, an ECG circuit module 403, one or more electrochemical circuit modules (e.g., electrochemical circuit module 404 and electrochemical circuit module 405), one or more electrode interfaces (e.g., electrode interface 406 and electrode interface 407), etc. Optionally, PCB 305 may also include a temperature module 408, etc. In some embodiments, ADC 402 may also be integrated into MCU 401.
[0243] The ECG circuit module 403 can be connected to the ECG electrodes. When a bipolar lead system is used to measure ECG, the ECG electrodes can include an LA electrode, an RA electrode, and an RLD electrode. The LA electrode and the RA electrode can measure ECG signal 1 and transmit ECG signal 1 to the ECG circuit module 403. The ECG circuit module 403 can amplify, filter, and perform other processing on ECG signal 1 to obtain ECG signal 2, and then send ECG signal 2 to the ADC 402. In some embodiments, the ECG circuit module 403 can include an amplifier circuit 4031, a filter circuit 4032, and a right leg drive (RLD) circuit 4033. The amplifier circuit 4031 can be connected to the LA electrode and the RA electrode, and the RLD circuit 4033 can be connected to the RLD electrode. The amplifier circuit 4031 can receive ECG signal 1 and amplify it. The RLD circuit 4033 can cancel common-mode signals, and the filter circuit 4032 can filter the amplified ECG signal 1 to obtain ECG signal 2.
[0244] The one or more electrochemical circuit modules may include electrochemical circuit module 404 and electrochemical circuit module 405. Each electrochemical circuit may measure a physiological parameter, such as blood glucose, blood ketones, uric acid, blood lactate, etc. The physiological parameters measured by electrochemical circuit module 404 and electrochemical circuit module 405 may be the same or different.
[0245] The electrochemical circuit module 404 can be connected to one or more electrochemical electrodes. When a three-electrode system is used to measure physiological parameters, the electrochemical circuit module 404 can be connected to one or more working electrodes, one or more reference electrodes, and one or more counter electrodes. The one or more electrochemical electrodes can react with the target substance 1 to generate a current signal 1, and conduct the current signal 1 to the electrochemical circuit module 404. The electrochemical circuit module 404 can amplify the current signal 1 and perform other processing to obtain a current signal 2, and send the current signal 2 to the ADC 402. In some embodiments, the electrochemical circuit module 404 may include a constant potential meter circuit 4041 and a transimpedance circuit 4042. The constant potential meter circuit 4041 can control the voltage difference between the reference electrode and the working electrode. The transimpedance circuit 4042 can amplify the current signal 1 to obtain a current signal 2. In some embodiments, the constant potentiostat circuit 4041 and the transimpedance circuit 4042 may have overlapping parts, for example, there may be one or more elements shared by the constant potentiostat circuit 4041 and the transimpedance circuit 4042. For specific examples, please refer to the relevant content in the embodiments shown in Figures 4C-4D and Figures 4F-4J below, which will not be described in detail here.
[0246] The electrochemical circuit module 405 can be connected to one or more electrochemical electrodes. When a three-electrode system is used to measure physiological parameters, the electrochemical circuit module 405 can be connected to one or more working electrodes, one or more reference electrodes, and one or more counter electrodes. The one or more electrochemical electrodes can react with the target substance 2 to generate a current signal 3, and conduct the current signal 3 to the electrochemical circuit module 405. The electrochemical circuit module 405 can amplify the current signal 3 and perform other processing to obtain a current signal 4, and send the current signal 4 to the ADC 402. In some embodiments, the electrochemical circuit module 405 may include a constant potential meter circuit 4051 and a transimpedance circuit 4052. The constant potential meter circuit 4051 can control the voltage difference between the reference electrode and the working electrode. The transimpedance circuit 4052 can amplify the current signal 3 to obtain a current signal 4. In some embodiments, the constant potentiostat circuit 4051 and the transimpedance circuit 4052 may have overlapping parts, for example, there may be one or more elements shared by the constant potentiostat circuit 4051 and the transimpedance circuit 4052. For specific examples, please refer to the relevant content in the embodiments shown in Figures 4C-4D and Figures 4F-4J below, which will not be described in detail here.
[0247] The one or more electrode interfaces may include an electrode interface 406 and an electrode interface 407. The electrode interface may connect the electrochemical circuit module with one or more electrochemical electrodes, and may also connect the ECG circuit module 403 with ECG electrodes.
[0248] In some embodiments, electrode interface 406 can connect electrochemical circuit module 404 with one or more electrochemical electrodes. Electrode interface 406 can also connect ECG circuit module 403 with the LA electrode. Electrode interface 407 can connect electrochemical circuit module 405 with one or more electrochemical electrodes. Electrode interface 407 can also connect ECG circuit module 403 with the RA electrode and the RLD electrode.
[0249] Exemplarily, if the electronic device 200 is the electronic device 200 shown in Figures 3A-3B above, the electrochemical electrodes connected to the electrode interface 406 may include the working electrode 3031, the reference electrode 3032 and the counter electrode 3033 in the embodiment shown in Figure 3B above, and the LA electrode connected to the electrode interface 406 may be the reference electrode 3032; the electrochemical electrodes connected to the electrode interface 407 may include the working electrode 3041, the reference electrode 3042 and the counter electrode 3043 in the embodiment shown in Figure 3B above, and the RA electrode connected to the electrode interface 407 may be the working electrode 3041, and the RLD electrode may be the counter electrode 3043.
[0250] As another example, if the electronic device 200 is the electronic device 200 shown in Figures 3D-3E above, the electrochemical electrodes connected to the electrode interface 406 may include the working electrode group 3082, the reference electrode group 3083, and the counter electrode group 3084 in the embodiment shown in Figure 3D above, and the LA electrode connected to the electrode interface 406 may be the LA electrode 3081; the electrochemical electrodes connected to the electrode interface 407 may include the working electrode group 3073, the reference electrode group 3074, and the counter electrode group 3075 in the embodiment shown in Figure 3D above, and the RA electrode connected to the electrode interface 407 may be the RA electrode 3071, and the RLD electrode may be the RLD electrode 3072. It will be understood that the above two embodiments are merely examples. In the embodiments of the present application, the connection relationship between the electrode interface and the electrodes (including electrochemical electrodes and ECG electrodes) may also be a connection relationship different from that in the above embodiments, and the present application does not limit this.
[0251] ADC402 can receive the current signal (e.g., current signal 2, current signal 4, etc.) sent by the one or more electrochemical circuit modules. ADC402 can also receive the analog ECG signal 2 sent by the ECG circuit module 403. ADC402 can perform analog-to-digital conversion on the received analog signal (e.g., current signal 2, current signal 4, ECG signal 2, etc.) to obtain the corresponding digital signal. For example, ADC402 can perform analog-to-digital conversion on current signal 2 to obtain current signal 5. ADC402 can perform analog-to-digital conversion on current signal 4 to obtain current signal 6. ADC402 can also perform analog-to-digital conversion on ECG signal 2 to obtain ECG signal 3. The above-mentioned current signal 5, current signal 6, and ECG signal 3 are all digital signals.
[0252] MCU401 can receive digital signals (e.g., current signal 5, current signal 6, and ECG signal 3) sent by ADC402, and can also receive a temperature signal sent by temperature module 408. MCU401 can determine the user's electrocardiogram based on ECG signal 3 sent by ADC402. MCU401 can determine the user's physiological parameter 1 based on current signal 5 sent by ADC402, and can also determine the user's physiological parameter 2 based on current signal 6. Optionally, MCU401 can also determine the user's body temperature based on the temperature signal.
[0253] The temperature module 408 can detect a temperature signal and send the temperature signal to the MCU 401 .
[0254] In some embodiments, the PCB 305 may further include a charging circuit module 409 , which may provide power to other modules in the PCB 305 .
[0255] The charging circuit module 409 may include a charging management chip 4092 and a voltage stabilizing circuit 4094. Optionally, the charging circuit module 409 may also include a battery 4093 and a charging interface 4091. In some embodiments, the battery 4093 may not be disposed in the PCB 305, but may be connected to the charging circuit module 409 in the PCB 305.
[0256] The charging interface 4091 can receive charging input (e.g., charging input from a wired charger, wireless charging input, etc.), charge the battery 4093 via the charging management chip 4092, and transmit power to the voltage stabilization circuit 4094 via the charging management chip 4092.
[0257] The voltage stabilizing circuit 4094 can provide power with a stable voltage to other circuit modules in the PCB 305. The voltage stabilizing circuit 4094 can receive power transmitted by the charge management chip 4092, and can also receive power transmitted by the battery 4093.
[0258] It can be understood that the embodiment shown in Figure 4A is only an example. In the embodiment of the present application, PCB305 may also include more, fewer or different circuit modules (such as electrochemical circuit modules, electrode interfaces, etc.) than the above embodiment. Moreover, the connection relationship between the circuit modules in PCB305 may also be a connection relationship different from the above embodiment, and the present application does not limit this.
[0259] In some embodiments, the same electrochemical circuit module in PCB 305 can be used to measure multiple physiological parameters, and PCB 305 can control the physiological parameters measured by the electrochemical circuit module through one or more switches.
[0260] For example, FIG4B shows a schematic diagram of the connection relationship between various circuit modules in another PCB 305 provided in an embodiment of the present application.
[0261] As shown in FIG4B , PCB 305 may include a microcontroller unit (MCU), an analog-to-digital converter (ADC) 402, an ECG circuit module 403, a switch MUX0, one or more electrochemical circuit modules (e.g., electrochemical circuit module 404), one or more electrode interfaces (e.g., electrode interface 406, electrode interface 407), etc. Optionally, PCB 305 may also include, but is not limited to, any one or more of the following: a temperature module 408, a charging circuit module 409, etc. Among them:
[0262] The input end of the switch MUX0 can be connected to the electrode interface 406 and the electrode interface 407. The output end of the switch MUX0 can be connected to the electrochemical circuit module 404. The switch MUX0 can connect the electrode interface 406 or the electrode interface 407.
[0263] The electrochemical circuit module 404 can be connected to a plurality of electrochemical electrodes via a switch MUX0 .
[0264] When MUX0 is connected to the electrode interface 406, the electrochemical circuit module 404 can be connected to one or more electrochemical electrodes through MUX0 and the electrode interface 406. In the case of measuring physiological parameters using a three-electrode system, the one or more electrochemical electrodes may include one or more working electrodes, one or more reference electrodes, and one or more counter electrodes. The one or more electrochemical electrodes can react with the target substance 1 to generate a current signal 1, and conduct the current signal 1 to the electrochemical circuit module 404. The electrochemical circuit module 404 can amplify the current signal 1 and perform other processing to obtain a current signal 2, and send the current signal 2 to the ADC402.
[0265] When MUX0 is connected to the electrode interface 407, the electrochemical circuit module 404 can be connected to one or more electrochemical electrodes through MUX0 and the electrode interface 407. In the case of measuring physiological parameters using a three-electrode system, the one or more electrochemical electrodes may include one or more working electrodes, one or more reference electrodes, and one or more counter electrodes. The one or more electrochemical electrodes can react with the target substance 2 to generate a current signal 3, and conduct the current signal 3 to the electrochemical circuit module 404. The electrochemical circuit module 404 can amplify the current signal 3 and other processing to obtain a current signal 4, and send the current signal 4 to the ADC402.
[0266] In some embodiments, the electrochemical circuit module 404 may include a constant potential meter circuit 4041 and a transimpedance circuit 4042. The constant potential meter circuit 4041 can control the voltage difference between the reference electrode and the working electrode. The transimpedance circuit 4042 can amplify the current signal, for example, amplifying the current signal 1 to obtain the current signal 2, or amplifying the current signal 3 to obtain the current signal 4. In some embodiments, there may be an overlapping portion between the constant potential meter circuit 4041 and the transimpedance circuit 4042, for example, there may be one or more elements shared by the constant potential meter circuit 4041 and the transimpedance circuit 4042. For specific examples, please refer to the relevant content in the embodiments shown in Figures 4C-4D and Figures 4F-4J below, which will not be described in detail here.
[0267] The one or more electrode interfaces may include an electrode interface 406 and an electrode interface 407. The electrode interface may connect the electrochemical circuit module with one or more electrochemical electrodes, and may also connect the ECG circuit module 403 with the ECG electrodes. In some embodiments, the electrode interface 406 may connect the switching switch MUX0 with one or more electrochemical electrodes. The electrode interface 406 may also connect the ECG circuit module 403 with the LA electrode. The electrode interface 407 may connect the switching switch MUX0 with one or more electrochemical electrodes, and the electrode interface 407 may also connect the ECG circuit module 403 with the RA electrode and the RLD electrode. The connection relationship between the electrode interface 406, the electrode interface 407 and each electrode may refer to the relevant description in the embodiment shown in FIG. 4A above, and will not be repeated here.
[0268] In addition, the specific contents of MCU 401 , ADC 402 , ECG circuit module 403 , temperature module 408 and charging circuit module 409 can be referred to the relevant description in the embodiment shown in FIG. 4A above, which will not be repeated here.
[0269] It will be understood that the embodiment shown in FIG4B is merely an example. In embodiments of the present application, PCB 305 may include more, fewer, or different circuit modules (e.g., electrochemical circuit modules, electrode interfaces, etc.) than those in the aforementioned embodiment. Furthermore, the connection relationships between the various circuit modules in PCB 305 may also differ from those in the aforementioned embodiment, which is not limited herein. Furthermore, in some embodiments, a single electrochemical module may be used to measure more than two physiological parameters, which is not limited herein.
[0270] In other embodiments, more or fewer switching switches may be provided in PCB305, or switching switches may be provided at different positions from the embodiment shown in FIG4B above. These switching switches may be used to control PCB305 to measure the current signal / ECG signal of a specified physiological parameter at the same time, or to measure the ECG signal and the current signal of one or more physiological parameters at the same time.
[0271] The following uses the example that both electrode group 1 and electrode group 2 can form a three-electrode system to introduce various measurement circuits provided in the embodiments of the present application.
[0272] FIG4C shows a circuit diagram of a measurement circuit provided in an embodiment of the present application.
[0273] As shown in FIG4C , the measurement circuit may include a potentiostat circuit 1, a transimpedance circuit 1, a potentiostat circuit 2, a transimpedance circuit 2, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital conversion module ADC, and an MCU. Optionally, the measurement circuit may also include any one or more of the following: a discrete Fourier transform module DFT and a temperature module temp. Furthermore, the measurement circuit may also include multiple electrode groups, such as electrode group 1 and electrode group 2. For example, electrode group 1 may include a working electrode W1, a reference electrode R1, and a counter electrode C1; and electrode group 2 may include a working electrode W2, a reference electrode R2, and a counter electrode C2.
[0274] The following introduces the components in each circuit module and how to connect them.
[0275] The potentiostat circuit 1 may include a digital-to-analog conversion module DAC1, an operational amplifier AMP_1, and an operational amplifier AMP_2. Each operational amplifier may include a non-inverting input, an inverting input, and an output. DAC1 can generate a stable voltage signal. DAC1 can be connected to the non-inverting input of operational amplifier AMP_1 and the non-inverting input of operational amplifier AMP_2, providing the same voltage input to both operational amplifiers AMP_1 and AMP_2. The output of operational amplifier AMP_1 can be connected to the counter electrode C1 in electrode set 1, and the inverting input of operational amplifier AMP_1 can be connected to the reference electrode R1 in electrode set 1. The inverting input of operational amplifier AMP_2 can be connected to the working electrode W1 in electrode set 1, and the output of operational amplifier AMP_2 can be connected to an ADC. Thus, by applying the same voltage to the non-inverting inputs of operational amplifiers AMP_1 and AMP_2, the voltage difference between reference electrode R1 and working electrode W1 can be controlled so that the voltage on working electrode W1 is approximately equal to the voltage on reference electrode R1.
[0276] The transimpedance circuit 1 may include an operational amplifier AMP_2 and a resistor RTIA_1. The two ends of the resistor RTIA_1 are respectively connected to the inverting input and output of the operational amplifier AMP_2. In this way, when there is a stable voltage input to the non-inverting input of the operational amplifier AMP_2, the transimpedance circuit 1 can amplify the current signal input to the inverting input of the operational amplifier AMP_2. Since the inverting input of the operational amplifier AMP_2 is connected to the working electrode W1 in the electrode group 1, and the output of the operational amplifier AMP_2 is connected to the ADC, the transimpedance circuit 1 can amplify the current signal conducted by the working electrode W1 and transmit the amplified current signal to the ADC.
[0277] The potentiostat circuit 2 may include a digital-to-analog conversion module DAC2, an operational amplifier AMP_5, and an operational amplifier AMP_6. DAC2 may generate a stable voltage signal. DAC2 may be connected to the non-inverting input of the operational amplifier AMP_5, and may also be connected to the non-inverting input of the operational amplifier AMP_6, providing the same voltage input to the operational amplifier AMP_5 and the operational amplifier AMP_6. The output of the operational amplifier AMP_5 may be connected to the counter electrode C2 in the electrode group 2, and the inverting input of the operational amplifier AMP_5 may be connected to the reference electrode R2 in the electrode group 2. The inverting input of the operational amplifier AMP_6 may be connected to the working electrode W2 in the electrode group 2, and the output of the operational amplifier AMP_6 may be connected to the ADC. In this way, by applying the same voltage to the non-inverting inputs of the operational amplifier AMP_5 and the operational amplifier AMP_6, the voltage difference between the reference electrode R2 and the working electrode W2 may be controlled so that the voltage on the working electrode W2 is approximately equal to the voltage on the reference electrode R2. It should be noted that, in some embodiments, the constant potentiostat circuit 2 may also share a digital-to-analog conversion module DAC1 with the constant potentiostat circuit 1. In this case, the digital-to-analog conversion module DAC2 in the constant potentiostat circuit 2 may also be replaced by the digital-to-analog conversion module DAC1, which is not limited in this application.
[0278] The transimpedance circuit 2 may include an operational amplifier AMP_6 and a resistor RTIA_2. The two ends of the resistor RTIA_2 are respectively connected to the inverting input and output of the operational amplifier AMP_6. In this way, when there is a stable voltage input to the non-inverting input of the operational amplifier AMP_6, the transimpedance circuit 2 can amplify the current signal input to the inverting input of the operational amplifier AMP_6. Since the inverting input of the operational amplifier AMP_6 is connected to the working electrode W2 in the electrode group 2, and the output of the operational amplifier AMP_6 is connected to the ADC, the transimpedance circuit 2 can amplify the current signal conducted by the working electrode W2 and transmit the amplified current signal to the ADC.
[0279] The amplification module may include an instrumentation amplifier IA, which may be a component integrated with multiple operational amplifiers. The instrumentation amplifier IA may include a non-inverting input terminal, an inverting input terminal, and an output terminal. The instrumentation amplifier IA may perform differential operations on the signals at the non-inverting input terminal and the inverting input terminal, amplifying the differential-mode signal between the non-inverting input terminal and the inverting input terminal. At the same time, the instrumentation amplifier IA only plays a following role for the common-mode signal, thereby increasing the ratio between the amplitudes of the differential-mode signal and the common-mode signal, thereby suppressing the common-mode signal. The non-inverting input terminal of the instrumentation amplifier IA may be connected to the reference electrode R1 in electrode group 1, and the inverting input terminal may be connected to the working electrode W2 in electrode group 2. In this case, the reference electrode R1 may be regarded as the LA electrode, and the working electrode W2 may be regarded as the RA electrode. In this way, the instrumentation amplifier IA may amplify the potential difference between the LA electrode and the RA electrode, and transmit the amplified ECG signal to the filtering circuit.
[0280] In some embodiments, the right leg drive circuit may include an operational amplifier AMP_3, multiple resistors, and a capacitor C1. The multiple resistors may include resistors R1, R2, R3, and R4. The non-inverting input of the operational amplifier AMP_3 may be connected to a voltage source VCM_REF, which may apply a stable voltage to the operational amplifier AMP_3. The inverting input of the operational amplifier AMP_3 may be connected to an instrumentation amplifier IA via resistor R2 to receive the common-mode signal output by the instrumentation amplifier IA. Furthermore, the output of the operational amplifier AMP_3 may be connected to the counter electrode C2 in the electrode group 2 via resistor R1, whereby the counter electrode C2 may be considered the RLD electrode. The two ends of the resistor R3 may be connected to the output and inverting input of the operational amplifier AMP_3, respectively; the two ends of the resistor R4 may be connected to the capacitor C1 and the output of the operational amplifier AMP_3, respectively; and the two ends of the capacitor C1 may be connected to the resistor R4 and the inverting input of the operational amplifier AMP_3, respectively. That is, the resistor R4 and the capacitor C1 are connected in series, and the branch formed by the series connection of the resistor R4 and the capacitor C1 is connected in parallel with the resistor R3. The right leg drive circuit can apply an inverted signal of the common-mode signal through the RLD electrode, thereby canceling the common-mode signal.
[0281] The filtering circuit may include multiple filters, such as filter 1 and filter 2, and optionally, an operational amplifier AMP_4. In some embodiments, filter 1 may be connected to the output of the instrumentation amplifier IA and the input of the operational amplifier AMP_4, and filter 2 may be connected to the output of the operational amplifier AMP_4 and the input of the ADC. The filtering circuit may receive the amplified ECG signal transmitted by the amplification circuit, perform one or more operations such as filtering and amplification on the amplified ECG signal, and transmit the processed ECG signal to the ADC.
[0282] The DFT module is an optional module. It can perform DFT processing on the digital signal transmitted by the ADC and transmit it to the MCU.
[0283] The specific functions of the ADC, MCU and temperature module temp can be referred to the relevant description in the embodiment shown in Figure 4A or Figure 4B above, and will not be repeated here.
[0284] It should be noted that, in the embodiment shown in FIG. 4C , the electrode group 1 and the electrode group 2 may be the electrode group 1 and the electrode group 2 in the embodiment shown in FIG. 3A to FIG. 3B or FIG. 3D to FIG. 3E .
[0285] It will be understood that the embodiment shown in FIG. 4C is merely an example. In embodiments of the present application, the measurement circuit may further include more electrode groups, potentiostat circuits, and transimpedance circuits to measure more physiological parameters, and this application does not limit this. Furthermore, each circuit module of the measurement circuit may further include more, fewer, or different components than those in the above embodiment, and this application does not limit this.
[0286] FIG4D shows a circuit diagram of another measurement circuit provided in an embodiment of the present application.
[0287] As shown in Figure 4D, the measurement circuit may include a potentiostat circuit 1, a transimpedance circuit 1, a potentiostat circuit 2, a transimpedance circuit 2, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital conversion module ADC, and an MCU. Optionally, the measurement circuit may also include any one or more of the following: a discrete Fourier transform module DFT and a temperature module temp. Furthermore, the measurement circuit may also include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include one or more working electrodes W1, one or more reference electrodes R1, and one or more counter electrodes C1. Furthermore, electrode group 1 may also include an LA electrode. Electrode group 2 may include one or more working electrodes W2, one or more reference electrodes R2, and one or more counter electrodes C2. Furthermore, electrode group 2 may also include an RA electrode and an RLD electrode.
[0288] The connection relationships between the electrodes in electrode group 1 and electrode group 2 and other circuit elements are described below.
[0289] In electrode set 1, the one or more counter electrodes C1 can be connected to the output of operational amplifier AMP_1; the one or more reference electrodes R1 can be connected to the inverting input of operational amplifier AMP_1; the one or more working electrodes W1 can be connected to the inverting input of operational amplifier AMP_2; and the LA electrode can be connected to the non-inverting input of instrumentation amplifier IA. Operational amplifiers AMP_1 and AMP_2 belong to potentiostat circuit 1, and instrumentation amplifier IA belongs to amplifier circuit.
[0290] In electrode set 2, the one or more counter electrodes C2 can be connected to the output of operational amplifier AMP_5; the one or more reference electrodes R2 can be connected to the inverting input of operational amplifier AMP_5; the one or more working electrodes W2 can be connected to the inverting input of operational amplifier AMP_6; the RA electrode can be connected to the inverting input of instrumentation amplifier IA, and the RLD electrode can be connected to the output of operational amplifier AMP_3 via resistor R1. Operational amplifiers AMP_5 and AMP_6 belong to potentiostat circuit 2, instrumentation amplifier IA belongs to the amplifier circuit, and operational amplifier AMP_3 and resistor R1 belong to the right leg drive circuit.
[0291] It should be noted that in electrode group 1 or electrode group 2, the one or more electrodes with the same function can be connected to external components in parallel. The specific connection method can refer to the relevant content in the embodiment shown in Figure 4E below, which will not be described in detail here.
[0292] In addition, the specific contents of the constant potential meter circuit 1, the transimpedance circuit 1, the constant potential meter circuit 2, the transimpedance circuit 2, the right leg drive circuit, the amplifier circuit, the filter circuit, the MCU, the ADC, the DFT, and the temperature module temp can be referred to the relevant contents in the embodiment shown in Figure 4C above, and will not be repeated here.
[0293] In the embodiment shown in FIG4D , electrode group 1 and electrode group 2 may be the electrode group 1 and electrode group 2 in the embodiment shown in FIG3A-FIG3B , or FIG3D-FIG3E .
[0294] It will be understood that the embodiment shown in FIG. 4D is merely an example. In embodiments of the present application, the measurement circuit may further include more electrode groups, potentiostat circuits, and transimpedance circuits to measure more physiological parameters, and this application does not limit this. Furthermore, each circuit module of the measurement circuit may further include more, fewer, or different components than those in the above embodiment, and this application does not limit this.
[0295] By using the measurement circuit shown in FIG. 4C or FIG. 4D , multiple physiological parameters and the user's electrocardiogram signal can be measured simultaneously.
[0296] FIG4E shows a schematic diagram of a connection method between one or more electrodes with the same function in an array sensor 1 provided in an embodiment of the present application and other elements in a circuit.
[0297] As shown in FIG4E , the array sensor 1 may include one or more working electrodes W1, one or more reference electrodes R1, one or more counter electrodes C1, and an LA electrode. The one or more working electrodes W1 may include a working electrode W11, a working electrode W12, and a working electrode W13; the one or more reference electrodes R1 may include a reference electrode R11, a reference electrode R12, and a reference electrode R13; and the one or more counter electrodes C1 may include a counter electrode C11, a counter electrode C12, and a counter electrode C13.
[0298] Taking the array sensor 1 including the electrode assembly 1 shown in FIG. 4D as an example, working electrodes W11, W12, and W13 can be connected in parallel to the same port, such as the inverting input of operational amplifier AMP_2 in the embodiment shown in FIG. 4D . Reference electrodes R11, R12, and R13 can be connected in parallel to the same port, such as the inverting input of operational amplifier AMP_1 in the embodiment shown in FIG. 4D . Counter electrodes C11, C12, and C13 can be connected in parallel to the same port, such as the output of operational amplifier AMP_1 shown in FIG. 4D .
[0299] It can be understood that the embodiment shown in Figure 4E above is only an example of how electrodes with the same function in the array sensor can be connected in parallel to the same port of the same element in the measurement circuit. In the embodiment of the present application, the number of electrodes with different functions in the array sensor 1 may also be different from that in the above embodiment, and other array sensors or microneedle sensors (for example, a microneedle sensor having multiple electrochemical electrodes of the same type) may also be connected to the elements in the measurement circuit in the manner shown in the above embodiment. The present application does not limit this.
[0300] In one possible implementation, multiple electrode groups in the measurement circuit can share an electrochemical circuit module (including a constant potential instrument circuit and a transimpedance circuit). In this case, the measurement circuit can also include a switching switch, which can be used to control the electrochemical circuit module to connect to electrode group 1 or electrode group 2.
[0301] FIG4F shows a circuit diagram of another measurement circuit provided in an embodiment of the present application.
[0302] As shown in Figure 4F, the measurement circuit may include a switch MUX0, a potentiostat circuit 1, a transimpedance circuit 1, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital conversion module (ADC), and an MCU. Optionally, the measurement circuit may also include any one or more of the following: a discrete Fourier transform module (DFT) and a temperature module (temp). Furthermore, the measurement circuit may include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include a working electrode W1, a reference electrode R1, and a counter electrode C1; electrode group 2 may include a working electrode W2, a reference electrode R2, and a counter electrode C2.
[0303] The switching switch MUX0 may include multiple input terminals, such as input terminal A01, input terminal A02, input terminal A03, input terminal B01, input terminal B02, and input terminal B03. The switching switch MUX0 may also include multiple output terminals, such as output terminal Y01, output terminal Y02, and output terminal Y03. Each output terminal of the switching switch MUX0 may correspond to multiple input terminals. Specifically, output terminal Y01 may correspond to input terminal A01 and input terminal B01, output terminal Y02 may correspond to input terminal A02 and input terminal B02, and output terminal Y03 may correspond to input terminal A03 and input terminal B03. MUX0 may control an output terminal to connect to one of the corresponding input terminals, for example, controlling output terminal Y01 to connect to input terminal A01 or input terminal B01, controlling output terminal Y02 to connect to input terminal A02 or input terminal B02, and controlling output terminal Y03 to connect to input terminal A03 or input terminal B03.
[0304] Output terminal Y01 can be connected to the output terminal of operational amplifier AMP_1, output terminal Y02 can be connected to the inverting input terminal of operational amplifier AMP_1, and output terminal Y03 can be connected to the inverting input terminal of operational amplifier AMP_2. Operational amplifier AMP_1 and operational amplifier AMP_2 belong to constant potentiostat circuit 1.
[0305] Input terminal A01 can be connected to counter electrode C2, input terminal A02 can be connected to reference electrode R2, and input terminal A03 can be connected to working electrode W2. Input terminal B01 can be connected to counter electrode C1, input terminal B02 can be connected to reference electrode R1, and input terminal B03 can be connected to working electrode W1.
[0306] When the switching switch MUX0 selects to connect the input terminal A01, the input terminal A02 and the input terminal A03, the constant potential instrument circuit 1 and the cross-group circuit 1 can be connected to the electrochemical electrode in the electrode group 2 through the switching switch MUX0; when the switching switch MUX0 selects to connect the input terminal B01, the input terminal B02 and the input terminal B03, the constant potential instrument circuit 1 and the cross-group circuit 1 can be connected to the electrochemical electrode in the electrode group 1 through the switching switch MUX0.
[0307] Furthermore, in electrode set 2, counter electrode C2 can also function as the RLD electrode, connected to the output of operational amplifier AMP_3 via resistor R1. Working electrode W2 can also function as the RA electrode, connected to the inverting input of instrumentation amplifier IA. In electrode set 1, reference electrode R1 can also function as the LA electrode, connected to the non-inverting input of instrumentation amplifier IA. The instrumentation amplifier IA is part of the amplifier circuit, while resistor R1 and operational amplifier AMP_3 are part of the right leg drive circuit.
[0308] In addition, the composition and connection of other components in the potentiostat circuit 1, transimpedance circuit 1, potentiostat circuit 2, transimpedance circuit 2, right leg drive circuit, amplifier circuit, filter circuit, etc., can refer to the relevant description of the embodiment shown in Figure 4C above, and will not be repeated here. Furthermore, the specific contents of the MCU, ADC, DFT, and temperature module temp can refer to the relevant contents of the embodiment shown in Figure 4C above, and will not be repeated here.
[0309] It is understood that the embodiment shown in FIG. 4F is merely an example. In embodiments of the present application, the measurement circuit may further include more electrode groups, potentiostat circuits, and transimpedance circuits, and the switching switch may further include more input terminals and output terminals, or more switching switches may further include to control the measurement of more physiological parameters, and this application does not limit this. Furthermore, each circuit module of the measurement circuit may further include more, fewer, or different components than those in the above-described embodiment, and this application does not limit this.
[0310] FIG4G shows a circuit diagram of another measurement circuit provided in an embodiment of the present application.
[0311] As shown in Figure 4G, the measurement circuit may include a switching switch MUX0, a potentiostat circuit 1, a transimpedance circuit 1, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital conversion module ADC, and an MCU. Optionally, the measurement circuit may also include any one or more of the following: a discrete Fourier transform module DFT and a temperature module temp. Furthermore, the measurement circuit may also include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include one or more working electrodes W1, one or more reference electrodes R1, and one or more counter electrodes C1. Electrode group 1 may also include an LA electrode. Electrode group 2 may include one or more working electrodes W2, one or more reference electrodes R2, and one or more counter electrodes C2. Electrode group 2 may also include an RA electrode and an RLD electrode.
[0312] The switching switch MUX0 may include multiple input terminals and output terminals, and each output terminal may correspond to multiple input terminals. The corresponding relationship between the input terminals and the output terminals in the switching switch MUX0, as well as the connection relationship between the input terminals, the output terminals and other components or electrodes, can refer to the relevant description of the embodiment shown in Figure 4F above, and will not be repeated here. It should be noted that the connection method between each electrochemical electrode and the switching switch MUX0 in electrode group 1 and electrode group 2 can refer to the relevant content of the embodiments shown in Figures 4E and 4F above.
[0313] When the switching switch MUX0 selects to connect the input terminal A01, the input terminal A02 and the input terminal A03, the constant potential instrument circuit 1 and the cross-group circuit 1 can be connected to the electrochemical electrode in the electrode group 2 through the switching switch MUX0; when the switching switch MUX0 selects to connect the input terminal B01, the input terminal B02 and the input terminal B03, the constant potential instrument circuit 1 and the cross-group circuit 1 can be connected to the electrochemical electrode in the electrode group 1 through the switching switch MUX0.
[0314] Furthermore, in electrode set 2, the RLD electrode is connected to the output of the operational amplifier AMP_3 via resistor R1, and the RA electrode can be connected to the inverting input of the instrumentation amplifier IA. In electrode set 1, the LA electrode can be connected to the non-inverting input of the instrumentation amplifier IA. The instrumentation amplifier IA is part of the amplifier circuit, while resistor R1 and the operational amplifier AMP_3 are part of the right leg drive circuit.
[0315] In addition, the composition and connection of other components in the potentiostat circuit 1, transimpedance circuit 1, potentiostat circuit 2, transimpedance circuit 2, right leg drive circuit, amplifier circuit, filter circuit, etc., can refer to the relevant description of the embodiment shown in Figure 4C above, and will not be repeated here. Furthermore, the specific contents of the MCU, ADC, DFT, and temperature module temp can refer to the relevant contents of the embodiment shown in Figure 4C above, and will not be repeated here.
[0316] It is understood that the embodiment shown in FIG. 4G is merely an example. In embodiments of the present application, the measurement circuit may further include more electrode groups, potentiostat circuits, and transimpedance circuits, and the switching switch may further include more input terminals and output terminals, or more switching switches may further include to control the measurement of more physiological parameters, and this application does not limit this. Furthermore, each circuit module of the measurement circuit may further include more, fewer, or different components than those in the above-described embodiments, and this application does not limit this.
[0317] By using the measurement circuit shown in FIG4F or FIG4G , it is possible to measure another physiological signal by switching the switch while measuring the electrocardiogram signal.
[0318] In another possible implementation, the electrochemical circuit module and the ECG circuit module in the measurement circuit may share one or more components (such as operational amplifiers, filters, etc.), and the measurement circuit may also include multiple switching switches, which may be used to control the one or more components to measure ECG signals or other physiological parameters.
[0319] FIG4H shows a circuit diagram of a measurement circuit provided in an embodiment of the present application.
[0320] As shown in Figure 4H, the measurement circuit may include multiple switches, a potentiostat circuit 0, a transimpedance circuit 0, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital conversion module (ADC), and an MCU. Optionally, the measurement circuit may also include any one or more of the following: a discrete Fourier transform module (DFT) and a temperature module (temp). Furthermore, the measurement circuit may include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include a working electrode W1, a reference electrode R1, and a counter electrode C1; electrode group 2 may include a working electrode W2, a reference electrode R2, and a counter electrode C2.
[0321] The multiple switches may include switch MUX1, switch MUX2, and switch MUX3. Switch MUX1 may be used to control the microneedle sensor connected to potentiostat circuit 0 and transimpedance circuit 0. Switch MUX2 and switch MUX3 may be used to control the measurement circuit to measure electrocardiogram signals or other physiological parameters.
[0322] The following describes the ports of multiple switches and how to connect them.
[0323] The switching switch MUX1 can include multiple input terminals, such as input terminal A11, input terminal A12, input terminal A13, input terminal B11, input terminal B12, and input terminal B13. The switching switch MUX1 can also include multiple output terminals, such as output terminal Y11, output terminal Y12, and output terminal Y13. Each output terminal of the switching switch MUX1 can correspond to multiple input terminals, and MUX1 can control the output terminal to connect to one of the input terminals corresponding to the output terminal. Specifically, output terminal Y11 can correspond to input terminal A11 and input terminal B11, output terminal Y12 can correspond to input terminal A12 and input terminal B12, and output terminal Y13 can correspond to input terminal A13 and input terminal B13.
[0324] The output terminal Y11 can be connected to the output terminal of the operational amplifier AMP_7, the output terminal Y12 can be connected to the input terminal B22 of the switching switch MUX2, the output terminal Y12 can also be connected to the input terminal A31 of the switching switch MUX3, the output terminal Y12 can also be connected to the non-inverting input terminal of the instrumentation amplifier IA through the resistor R6, the output terminal Y12 can also be connected to the LA electrode (for example, the reference electrode R1 in the electrode group 1), and the output terminal Y13 can be connected to the input terminal A32 of the switching switch MUX3.
[0325] Input terminal A11 can be connected to counter electrode C2, input terminal A12 can be connected to reference electrode R2, and input terminal A13 can be connected to working electrode W2. Input terminal B11 can be connected to counter electrode C1, input terminal B12 can be connected to reference electrode R1, and input terminal B13 can be connected to working electrode W1.
[0326] When the switching switch MUX1 selects to connect the input terminal A11, the input terminal A12 and the input terminal A13, the constant potential instrument circuit 0 and the cross-group circuit 0 can be connected to the electrochemical electrode in the electrode group 2 through the switching switch MUX1; when the switching switch MUX1 selects to connect the input terminal B11, the input terminal B12 and the input terminal B13, the constant potential instrument circuit 0 and the cross-group circuit 0 can be connected to the electrochemical electrode in the electrode group 1 through the switching switch MUX1.
[0327] Switch MUX2 can include multiple input terminals, such as input terminal A21, input terminal A22, input terminal B21, and input terminal B22. Switch MUX2 can also include multiple output terminals, such as output terminal Y21 and output terminal Y22. Each output terminal of switch MUX2 can correspond to multiple input terminals, and MUX2 can control an output terminal to connect to one of the input terminals corresponding to the output terminal. Output terminal Y21 can correspond to input terminal A21 and input terminal B21, and output terminal Y22 can correspond to input terminal A22 and input terminal B22.
[0328] The output terminal Y21 may be connected to the non-inverting input terminal of the operational amplifier AMP_7 , and the output terminal Y22 may be connected to the non-inverting input terminal of the operational amplifier AMP_8 .
[0329] Input terminal A21 can be connected to the digital-to-analog conversion module DAC0, and input terminal A22 can be connected to the digital-to-analog conversion module DAC0. Input terminal B21 can be connected to the working electrode W2 in electrode group 2, and input terminal B21 can also be connected to the non-inverting input terminal of the instrumentation amplifier IA through resistor R5. Input terminal B22 can be connected to the LA electrode (i.e., the reference electrode R1 in electrode group 1), and input terminal B22 can also be connected to the output terminal Y12 of the switch MUX1 and the input terminal A31 of the switch MUX3. Input terminal B22 can also be connected to the non-inverting input terminal of the instrumentation amplifier IA through resistor R6.
[0330] Switch MUX3 can include multiple input terminals, such as input terminal A31, input terminal A32, input terminal B31, and input terminal B32. Switch MUX3 can also include multiple output terminals, such as output terminal Y31 and output terminal Y32. Each output terminal of switch MUX3 can correspond to multiple input terminals, and MUX3 can control an output terminal to connect to one of the input terminals corresponding to the output terminal. Output terminal Y31 can correspond to input terminal A31 and input terminal B31, and output terminal Y32 can correspond to input terminal A32 and input terminal B32.
[0331] The output terminal Y31 can be connected to the inverting input terminal of the operational amplifier AMP_7, and the output terminal Y32 can be connected to the inverting input terminal of the operational amplifier AMP_8. The operational amplifier AMP_7 and the operational amplifier AMP_8 belong to the constant potential instrument circuit 0.
[0332] Input terminal A31 can be connected to the output terminal Y12 of switch MUX1 and the input terminal B22 of switch MUX2. Input terminal A32 can switch the output terminal Y13 of switch MUX1. Input terminal A32 can also be connected to the output terminal of operational amplifier AMP_8 via resistor RTIA_0. Input terminal B31 can be connected to the output terminal of instrumentation amplifier IA. Input terminal B31 can also be connected to the inverting input terminal of operational amplifier AMP_3 via resistor R2. Input terminal B32 can be connected to input terminal B31, that is, input terminals B31 and B32 have the same input.
[0333] When the switching switch MUX2 selects to connect input terminal A21 and input terminal A22, and the switching switch MUX3 selects to connect input terminal A31 and input terminal A32, the measurement circuit can measure the user's physiological parameters (such as blood sugar, blood ketones, etc.); when MUX2 selects to connect input terminal B21 and input terminal B22, and the switching switch MUX3 selects to connect input terminal B31 and input terminal B32, the measurement circuit can measure electrocardiogram signals.
[0334] Potentiostat circuit 0 may include a digital-to-analog converter module DAC0, an operational amplifier AMP_7, an operational amplifier AMP_8, a switch MUX2, and a switch MUX3. The connection of each component can be referenced to the description of switches MUX2 and MUX3 above. The functions of other components can be referenced to the description of the embodiments above and are not further described here. Furthermore, the output of operational amplifier AMP_7 can be connected to filter 1, and the output of operational amplifier AMP_8 can be connected to filter 2.
[0335] Cross-group circuit 0 may include an operational amplifier AMP_8, a resistor RTIA_0, and a switch MUX3. The connection of each component may refer to the description of switches MUX2 and MUX3 above. The functions of other components may refer to the description of the embodiments above, and will not be repeated here.
[0336] The amplifier circuit may include an instrumentation amplifier IA, and may also include resistors R5 and R6. Resistor R6 may be connected to the LA electrode (i.e., reference electrode R1) and the non-inverting input of the instrumentation amplifier IA, and resistor R5 may be connected to the RA electrode (i.e., working electrode W2) and the non-inverting input of the instrumentation amplifier IA. The inverting input of the instrumentation amplifier IA may be connected to the output of the instrumentation amplifier IA. For other connection relationships of the instrumentation amplifier IA, refer to the description of other components and are not repeated here.
[0337] The components and connections between them in the right leg drive circuit can be found in the description of the embodiment shown in FIG4C . Furthermore, the inverting input of the operational amplifier AMP_3 can be connected to the output of the instrumentation amplifier IA, as well as to the inputs B31 and B32 of the switch MUX3, via resistor R2.
[0338] The filtering circuit may include a filter Filter 1 and a filter Filter 2. The filtering circuit may be used to filter the signals output by the operational amplifier AMP_7 and the operational amplifier AMP_8.
[0339] The specific functional description of each module in the measurement circuit can refer to the relevant description in the embodiment shown in FIG4C above, which will not be repeated here.
[0340] It is understood that the embodiment shown in FIG. 4H is merely an example. In embodiments of the present application, the measurement circuit may further include more electrode groups, potentiostat circuits, and transimpedance circuits, and the switching switch may further include more inputs and outputs, or more switching switches may be included to control the measurement of more physiological parameters, and this application does not limit this. Furthermore, each circuit module of the measurement circuit may further include more, fewer, or different components than those in the above-described embodiment, and this application does not limit this.
[0341] FIG4I shows a circuit diagram of another measurement circuit provided in an embodiment of the present application.
[0342] As shown in Figure 4I, the measurement circuit may include multiple switches, a potentiostat circuit 0, a transimpedance circuit 0, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital conversion module ADC, and an MCU. Optionally, the measurement circuit may also include any one or more of the following: a discrete Fourier transform module DFT and a temperature module temp. Furthermore, the measurement circuit may also include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include one or more working electrodes W1, one or more reference electrodes R1, and one or more counter electrodes C1. Electrode group 1 may also include an LA electrode. Electrode group 2 may include one or more working electrodes W2, one or more reference electrodes R2, and one or more counter electrodes C2. Electrode group 2 may also include an RA electrode and an RLD electrode.
[0343] The multiple switches may include switch MUX1, switch MUX2, and switch MUX3. Switch MUX1 may be used to control potentiostat circuit 0 and transimpedance circuit 0 to connect to electrode group 1 or electrode group 2. Switch MUX2 and switch MUX3 may be used to control the measurement circuit to measure electrocardiographic signals or other physiological parameters.
[0344] The connection relationship between each electrode in electrode group 1 and electrode group 2 and the measurement circuit is introduced below.
[0345] In electrode group 1, the one or more working electrodes W1 can be connected to the input terminal B13 of the switching switch MUX1, the one or more reference electrodes R1 can be connected to the input terminal B12 of the switching switch MUX1, the one or more counter electrodes C1 can be connected to the input terminal B11 of the switching switch MUX1, the LA electrode can be connected to the non-inverting input terminal of the instrumentation amplifier IA through the resistor R6, and the LA electrode can also be connected to the output terminal Y12 of the switching switch MUX1.
[0346] In electrode group 2, the one or more working electrodes W2 can be connected to input terminal A13 of the switching switch MUX1, the one or more reference electrodes R2 can be connected to input terminal A12 of the switching switch MUX1, the one or more counter electrodes C2 can be connected to input terminal A11 of the switching switch MUX1, the RA electrode can be connected to the non-inverting input terminal of the instrumentation amplifier IA via resistor R5, and the RA electrode can also be connected to input terminal B21 of the switching switch MUX2. The RLD electrode can be connected to the output terminal of the operational amplifier AMP_3 via resistor R1.
[0347] When the switching switch MUX1 selects to connect the input terminal A11, the input terminal A12 and the input terminal A13, the constant potential instrument circuit 0 and the cross-group circuit 0 can be connected to the electrochemical electrode in the electrode group 2 through the switching switch MUX1; when the switching switch MUX1 selects to connect the input terminal B11, the input terminal B12 and the input terminal B13, the constant potential instrument circuit 0 and the cross-group circuit 0 can be connected to the electrochemical electrode in the electrode group 1 through the switching switch MUX1.
[0348] When the switching switch MUX2 selects to connect input terminal A21 and input terminal A22, and the switching switch MUX3 selects to connect input terminal A31 and input terminal A32, the measurement circuit can measure the user's physiological parameters (such as blood sugar, blood ketones, etc.); when MUX2 selects to connect input terminal B21 and input terminal B22, and the switching switch MUX3 selects to connect input terminal B31, input terminal B32 and input terminal B33, the measurement circuit can measure electrocardiogram signals.
[0349] The specific functional description of each module in the measurement circuit can refer to the relevant description in the embodiment shown in FIG4H above, which will not be repeated here.
[0350] It is understood that the embodiment shown in FIG. 4I above is merely an example. In embodiments of the present application, the measurement circuit may further include more electrode groups, potentiostat circuits, and transimpedance circuits, and the switching switch may further include more inputs and outputs, or more switching switches may be included to control the measurement of more physiological parameters, and this application does not limit this. Furthermore, each circuit module of the measurement circuit may further include more, fewer, or different components than those in the above embodiment, and this application does not limit this.
[0351] By using the measurement circuit shown in FIG. 4H or FIG. 4I , the electrocardiogram signal can be measured by switching the switch or the physiological parameters can be measured by the electrochemical electrodes.
[0352] In another possible implementation, the measurement circuit may include three or more electrochemical circuit modules, and the multiple working electrodes in the electrode assembly may be connected to different electrochemical circuit modules to measure different physiological parameters. In this way, the measurement circuit can simultaneously measure three or more physiological parameters and also simultaneously measure electrocardiographic signals.
[0353] Exemplarily, as shown in FIG4J , the measurement circuit may include a potentiostat circuit 1, a transimpedance circuit 1, a potentiostat circuit 2, a transimpedance circuit 2, a potentiostat circuit 3, a transimpedance circuit 3, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital conversion module ADC, and an MCU. Optionally, the measurement circuit may also include any one or more of the following: a discrete Fourier transform module DFT and a temperature module temp. Furthermore, the measurement circuit may also include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include one or more working electrodes W1, one or more reference electrodes R1, and one or more counter electrodes C1. Furthermore, electrode group 1 may also include an LA electrode. Electrode group 2 may include working electrodes W21 and W22, reference electrodes R21 and R22, counter electrodes C21 and C22. Furthermore, electrode group 2 may also include an RA electrode and an RLD electrode.
[0354] The internal components of the potentiostat circuit 1, transimpedance circuit 1, potentiostat circuit 2, transimpedance circuit 2, right leg drive circuit, amplifier circuit, filter circuit, and other circuits, as well as the connections between these components, can be found in the description of the embodiment shown in FIG4D above and will not be repeated here. The functional descriptions of the analog-to-digital conversion module ADC, discrete Fourier transform module DFT, and MCU can also be found in the description of the embodiment shown in FIG4D above.
[0355] The constant potential meter circuit 3 may include an operational amplifier AMP_9, an operational amplifier AMP_10 and a digital-to-analog conversion module DAC3. In some embodiments, the digital-to-analog conversion module DAC3 may also be replaced by the digital-to-analog conversion module DAC1 in the constant potential meter circuit 1, or replaced by the digital-to-analog conversion module DAC2 in the constant potential meter circuit 2, which is not limited in this application. Among them, DAC3 can generate a stable voltage signal. DAC3 can be connected to the non-inverting input terminal of the operational amplifier AMP_9, and can also be connected to the non-inverting input terminal of the operational amplifier AMP_10, providing the same voltage input for the operational amplifier AMP_9 and the operational amplifier AMP_10. The output terminal of the operational amplifier AMP_9 can be connected to the counter electrode C21 in the electrode group 2, and the inverting input terminal of the operational amplifier AMP_9 can be connected to the reference electrode R21 in the electrode group 2. The inverting input terminal of the operational amplifier AMP_10 can be connected to the working electrode W21 in the electrode group 2, and the output terminal of the operational amplifier AMP_10 can be connected to the ADC. In this way, by applying the same voltage to the non-inverting input terminals of the operational amplifier AMP_9 and the operational amplifier AMP_10, the voltage difference between the reference electrode R21 and the working electrode W21 can be controlled so that the voltage on the working electrode W21 is approximately equal to the voltage on the reference electrode R21.
[0356] The transimpedance circuit 3 may include an operational amplifier AMP_10 and a resistor RTIA_3. The two ends of the resistor RTIA_3 may be connected to the inverting input and output of the operational amplifier AMP_10, respectively. The inverting input of the operational amplifier AMP_10 may also be connected to the working electrode W21 in the electrode group 2.
[0357] The components of the potentiostat circuit 2 and the transimpedance circuit 2 and the connection relationship between the components can refer to the relevant description in the embodiment shown in FIG. 4D .
[0358] The connection relationship between the potentiostat circuit 2 and the multiple electrodes in the electrode set 2 is as follows: the output of the operational amplifier AMP_5 can be connected to the counter electrode C22 in the electrode set 2, and the inverting input of the operational amplifier AMP_5 can be connected to the reference electrode R22 in the electrode set 2. The inverting input of the operational amplifier AMP_6 can be connected to the working electrode W22 in the electrode set 2, and the output of the operational amplifier AMP_6 can be connected to the ADC. In this way, by applying the same voltage to the non-inverting inputs of the operational amplifiers AMP_5 and AMP_6, the voltage difference between the reference electrode R22 and the working electrode W22 can be controlled so that the voltage on the working electrode W22 is approximately equal to the voltage on the reference electrode R22.
[0359] The connection relationship between the transimpedance circuit 2 and the multiple electrodes in the electrode group 2 is as follows: the inverting input terminal of the operational amplifier AMP_6 can also be connected to the working electrode W22 in the electrode group 2.
[0360] The component composition of other modules in the measurement circuit and the connection relationship between the components can refer to the relevant content in the embodiment shown in Figure 4D above, and will not be repeated here.
[0361] It can be understood that the embodiment shown in Figure 4J above is only an exemplary description. Different working electrodes in the electrode group can be connected to different electrochemical circuit modules. In the embodiment of the present application, the measurement circuit can also include more or fewer electrochemical circuit modules than the above embodiment. The multiple working electrodes in electrode group 2 (or electrode group 1) can also be connected to different electrochemical circuit modules respectively to measure different physiological parameters. This application does not limit this.
[0362] In other embodiments, the same reference electrode and / or counter electrode can be connected to different electrochemical circuit modules (eg, different potentiostat circuits) to measure multiple different physiological parameters, which is not limited in this application.
[0363] It is understood that the embodiments shown in Figures 4C-4J above are merely examples. In embodiments of the present application, the measurement circuit may further include circuit modules and components that are more, fewer, or different from those in the above embodiments, or the connection method between the various components in the measurement circuit may also be different from that in the above embodiments, and this application does not limit this. For example, the measurement circuit (or the circuit module of the measurement circuit) shown in any of the above embodiments may further include one or more circuit switches, and the one or more circuit switches may also be used for the measurement circuit to measure one or more physiological parameters (or electrocardiogram signals), and this application does not limit this.
[0364] It should be noted that the electrode groups 1 and 2 in the embodiments shown in Figures 4C-4J can be provided in a microneedle sensor or an array sensor. Furthermore, the electrode groups 1 and 2 in the embodiments shown in Figures 4C-4J can also employ a dual-electrode system. In this dual-electrode system, the counter electrode and the working electrode can be connected in the same manner as in the aforementioned embodiment, and the counter electrode can also serve as a reference electrode connected to the port used for the reference electrode in the aforementioned embodiment. This is not a limitation of the present application.
[0365] The following describes the measurement method provided in the embodiments of the present application.
[0366] FIG5A shows a schematic flow chart of a measurement method provided in an embodiment of the present application.
[0367] As shown in FIG5A , the specific process of the measurement method may include the following steps:
[0368] S501. The electronic device 200 determines that monitoring condition 1 is met and determines physiological parameter 1.
[0369] Monitoring condition 1 may include but is not limited to any one or more of the following: receiving information 1 sent by other electronic devices to instruct the electronic device 200 to detect physiological parameters 1; detecting that the user is wearing the electronic device 200 (i.e., the electrodes of the electronic device 200 are implanted in the user's subcutaneous tissue); detecting an abnormal electrocardiogram signal.
[0370] For example, the electronic device 200 can determine whether the electronic device 200 is worn by the user based on whether the temperature detected by the temperature sensor falls within a preset body temperature range. It will be understood that this embodiment is only an example, and in the embodiments of the present application, the electronic device 200 can also use other methods to determine whether the electronic device 200 is worn, and this application does not limit this.
[0371] Physiological parameter 1 may include but is not limited to any one or more of the following: blood glucose, blood ketones, blood lactate, uric acid, etc.
[0372] In one possible implementation, when it is determined that monitoring condition 1 is satisfied, the electronic device 200 may measure physiological parameter 1, and stop monitoring after determining physiological parameter 1. In another possible implementation, when it is determined that monitoring condition 1 is satisfied, the electronic device 200 may periodically detect physiological parameter 1, for example, determining the value of physiological parameter 1 at the current moment every 10 minutes (or 20 minutes, 30 minutes, etc.). It should be noted that in this case, different physiological parameters may correspond to different monitoring periods, or may correspond to the same monitoring period, and this application does not limit this.
[0373] The electronic device 200 can obtain a reaction current generated by the reaction with the target substance 1 through the electrochemical electrode corresponding to the physiological parameter 1, and determine the physiological parameter 1 based on the magnitude of the reaction current.
[0374] For example, if physiological parameter 1 is blood glucose, and the electrochemical electrodes for measuring blood glucose include the working electrode 3031, reference electrode 3032, and counter electrode 3033 of the microneedle sensor 303 shown in FIG3B , then when the microneedle sensor 303 is implanted in subcutaneous tissue, the working electrode 3031 can react with glucose to generate a reaction current. The electronic device 200 can obtain the magnitude of this reaction current and, based on this magnitude, determine the blood glucose value using a blood glucose calculation model stored in the electronic device 200.
[0375] For example, if physiological parameter 1 is blood glucose, and the electrochemical electrodes for measuring blood glucose include the working electrode group 3073, reference electrode group 3074, and counter electrode group 3075 of the array sensor 307 shown in FIG3D , then when the array sensor 307 is implanted in subcutaneous tissue, the working electrode group 3073 can react with glucose to generate a reaction current. The electronic device 200 can obtain the magnitude of this reaction current and, based on this magnitude, determine the blood glucose value using a blood glucose calculation model stored in the electronic device 200.
[0376] It is understandable that the embodiments here are just two examples. In the embodiments of the present application, physiological parameter 1 may also be other physiological parameters different from blood glucose, or include multiple physiological parameters, and the present application does not limit this.
[0377] Optionally, the electronic device 200 may also measure the user's body temperature. In this case, further optionally, the electronic device 200 may also calibrate the value of the physiological parameter 1 based on the user's body temperature.
[0378] S502. The electronic device 200 outputs the physiological parameter 1.
[0379] In some embodiments, the electronic device 200 may include (or be connected to) an audio module and / or a display screen. In this case, the electronic device 200 may output the physiological parameter 1 by voice broadcast through the audio module, or may output the physiological parameter 1 by display screen display through the display screen.
[0380] In other embodiments, the electronic device 200 outputs the physiological parameter 1, which may also refer to sending output information 1 to other electronic devices (such as the electronic device 100). The output information 1 may include the physiological parameter 1, and the output information 1 can be used to instruct the receiving end to output the physiological parameter 1.
[0381] In some embodiments, the electronic device 200 may output any one or more of the following contents while outputting the user's physiological parameter 1 (or after outputting the physiological parameter 1): evaluation results, value range, user status, historical curve, reference suggestions, etc. The specific description and determination method of each content can refer to the relevant description in step S605 shown in Figure 6 below, which will not be described in detail here.
[0382] S503. The electronic device 200 determines that monitoring condition 2 is met and obtains an electrocardiogram signal.
[0383] It should be noted that there is no restriction on the execution order of step S503 and the above-mentioned step S501. The electronic device 200 can execute step S501 and step S503 at the same time, or execute one step first and then execute the other step. This application does not make any restriction on this.
[0384] Monitoring condition 2 may include but is not limited to any one or more of the following: receiving information 2 sent by other electronic devices to instruct the electronic device 200 to detect electrocardiogram signals; detecting a biological wearable electronic device 200 (i.e., the electrodes of the electronic device 200 are implanted in the subcutaneous tissue); detecting an abnormality in physiological parameter 1, etc.
[0385] Among them, the abnormality of physiological parameter 1 means that the value of physiological parameter 1 does not belong to the preset value range of physiological parameter 1, and the value range can be pre-stored by the electronic device 200. Exemplarily, the electronic device 200 can start to obtain the electrocardiogram signal when it detects that the user's blood sugar exceeds the preset blood sugar value range. It can be understood that the embodiment here is only an example of how to determine whether to obtain the electrocardiogram signal based on the value of the physiological parameter. In the embodiment of the present application, physiological parameter 1 can also be other physiological parameters different from blood sugar, or include multiple physiological parameters, and the present application does not limit it here.
[0386] It should be noted that, in the process of acquiring the ECG signal, the ECG electrode for measuring the ECG signal can be implanted in the subcutaneous tissue. In some embodiments, the ECG electrode can be an electrochemical electrode in the electronic device 200 for measuring other physiological parameters.
[0387] Exemplarily, if the electronic device 200 is the electronic device 200 in the embodiment shown in FIG. 3B , the ECG electrodes may be some of the electrochemical electrodes in microneedle sensors 303 and 304. For example, the LA electrode may be the reference electrode 3032, the RA electrode may be the working electrode 3041, and the RLD electrode may be the counter electrode 3043. Furthermore, if the electronic device 200 is the electronic device 200 in the embodiment shown in FIG. 3D , the ECG electrodes may be the ECG electrodes in array sensors 307 and 308. For example, the LA electrode may be the LA electrode 3081, the RA electrode may be the RA electrode 3071, and the RLD electrode may be the RLD electrode 3072. It will be understood that the embodiments herein are merely two examples. In the embodiments of the present application, when the ECG electrodes and the electrochemical electrodes share the same electrode, the corresponding relationship between the ECG electrodes and the electrochemical electrodes may also be different from that in the above embodiments, and the present application does not limit this.
[0388] In a bipolar lead system, the ECG signal may refer to the voltage difference between the LA electrode and the RA electrode within a preset time period (e.g., 1 minute, 3 minutes, etc.). When the electronic device 200 uses other lead systems to measure ECG signals, the ECG signal may also refer to the voltage difference between other electrodes within a preset time period, which is not limited in this application.
[0389] For example, FIG5B shows a waveform diagram of an electrocardiogram signal provided in an embodiment of the present application.
[0390] As shown in FIG5B , a two-dimensional coordinate system may include a horizontal axis and a vertical axis, where the horizontal axis may represent time and the vertical axis may represent voltage. The ECG signal waveform may be represented by a curve Q within this two-dimensional coordinate system. Curve Q indicates that the ECG signal waveform exhibits periodic fluctuations as the heart periodically pumps blood.
[0391] It is understandable that the embodiment shown in FIG5B is only an example. In the embodiment of the present application, the waveform of the ECG signal may also be a waveform different from that in the above embodiment, and the present application does not limit this.
[0392] S504. The electronic device 200 outputs an electrocardiogram signal.
[0393] In some embodiments, the electronic device 200 may include (or be connected to) an audio module and / or a display screen. In this case, the electronic device 200 may output the ECG signal by voice broadcast through the audio module, or may output the ECG signal by displaying it on the display screen.
[0394] In other embodiments, the electronic device 200 outputs an ECG signal, which may also refer to sending output information 2 to other electronic devices (such as the electronic device 100). The output information 2 may include the ECG signal, and the output information 2 can be used by the receiving end to output the ECG signal.
[0395] In some embodiments, the electronic device 200 (or the electronic device 100) can output the ECG signal in one or more different forms, such as in the form of a waveform (outputting an ECG), in the form of an ECG indicator, etc.
[0396] In some embodiments, the electronic device 200 (or the electronic device 100) may determine an electrocardiogram based on the electrocardiogram signal and display the electrocardiogram on a display screen. The electrocardiogram may be a waveform diagram of the electrocardiogram signal, which is used to represent the relationship between the amplitude and time of the electrocardiogram signal.
[0397] An electrocardiogram may include multiple different waves, such as a P wave, a QRS complex, a T wave, and a U wave. The following describes the waves in the electrocardiogram with reference to the electrocardiogram shown in FIG5C .
[0398] As shown in Figure 5C, the two-dimensional coordinate system may include a horizontal axis and a vertical axis, where the horizontal axis may represent time and the vertical axis may represent voltage. The waveform of the ECG signal in a single cardiac cycle may be a curve Q0 in the two-dimensional coordinate system.
[0399] As shown in Figure 5C, in curve Q0, the curve segment from t1 to t2 can be called the P wave; the curve segment from t2 to t3 can be called the QRS complex; the curve segment from t3 to t4 can be called the T wave; and the curve segment from t4 to t5 can be called the U wave. The point on curve Q0 at t3 can be called point J, which represents the end of the QRS complex. In addition, the period from t1 to t2 can be called the PR interval, and the period from t2 to t4 can be called the QT interval.
[0400] For example, the amplitude changes of curve Q0 in various time periods are as follows: from time t0 to time t1, the amplitude of curve Q0 is stable; from time t1 to time t2, the amplitude of curve Q0 first increases to the first peak point, then decreases, then returns to stability, and shows a downward trend at time t2; from time t2 to time t3, the amplitude of curve Q0 first decreases to the first trough point, then increases, increases to the second peak point, then decreases, decreases to the second trough point, and then increases again; from time t3 to time t4, the amplitude of curve Q0 gradually increases after a period of stability, increases to the third peak point, and then gradually decreases to the third trough point; from time t4 to time t5, the amplitude of curve Q0 increases from the third trough point to the fourth peak point, then decreases again, and then returns to stability. The amplitude of the second peak point is much higher than the amplitudes of the other peak points.
[0401] It can be understood that the embodiment shown in Figure 5C is only an example. In the embodiment of the present application, the electrocardiogram may also include more cycles than the above embodiment, and the waveform in each cycle may also be different from the above embodiment. For example, in some cycles, the P wave may also include two peaks, etc. This application does not limit this.
[0402] The individual waves and intervals in an electrocardiogram (ECG) can indicate a user's heart health. The P wave represents the depolarization process of the two atria. Because the sinus node is located at the junction of the right atrium and the superior vena cava, the impulse from the sinus node is first transmitted to the right atrium, then to the left atrium through the atrial bundle, forming the P wave on the ECG. The P wave represents atrial excitation, with the first half representing right atrial excitation and the second half representing left atrial excitation. When the atria are enlarged and conduction between the two atria is abnormal, the P wave appears as a peaked or double-peaked P wave. The PR interval represents the time from the onset of atrial depolarization to the onset of ventricular depolarization, primarily reflecting the time it takes for the impulse to conduct through the atrioventricular junction. Slow conduction velocity in the atrioventricular node results in the PR segment on the ECG. When conduction from the atria to the ventricles is blocked, this manifests as a prolonged PR interval or the disappearance of the ventricular wave after the P wave. The QRS complex represents the depolarization process of the ventricles. When there is conduction block in the left or right bundle branches of the heart, ventricular enlargement, or hypertrophy, the QRS complex will become widened, deformed, and prolonged. The J point represents the complete depolarization of the ventricular myocytes. The T wave represents the repolarization process of both ventricles. Changes in the T wave on the electrocardiogram are affected by various factors. For example, in cases of myocardial ischemia, the T wave may appear flat and inverted, while a tall T wave may be seen in hyperkalemia or the hyperacute phase of acute myocardial infarction. The U wave may be the waveform following the T wave and is currently believed to be related to ventricular repolarization. The QT interval represents the time required for the entire process of ventricular depolarization and repolarization. A prolonged QT interval is often associated with the occurrence of malignant arrhythmias.
[0403] The electronic device 200 can determine one or more ECG indicators based on the ECG signal. While outputting the ECG signal (or after outputting the ECG signal), the electronic device 200 can also output the one or more ECG indicators. ECG indicators can include, but are not limited to, any one or more of the following: heart rate, amplitude, PR interval, QT interval, and the duration of each wave (such as the P wave duration, etc.). Among them, the heart rate can be determined based on the number of cardiac cycles per minute in the ECG signal. The PR interval, QT interval, and P wave duration can all be determined based on the ECG (or ECG signal).
[0404] FIG6 shows a schematic flow chart of another measurement method provided in an embodiment of the present application.
[0405] As shown in FIG6 , the specific process of the measurement method may include the following steps:
[0406] S601 . The electronic device 100 determines that the monitoring condition 3 is satisfied, and sends information 3 to the electronic device 200 . The information 3 is used to request the electronic device 200 to send the physiological data 1 to the electronic device 100 .
[0407] In some embodiments, monitoring condition 3 may include but is not limited to any one or more of the following: receiving an operation by the user to turn on the physiological monitoring function, receiving a start-up instruction 1 sent by other electronic devices, detecting that the user's physiological state is abnormal (for example, the heart rate does not belong to the preset heart rate range, etc.), detecting that the user's psychological state is abnormal (for example, being frightened), detecting that the user is in motion, detecting that the user has insomnia, detecting that the user's body posture is abnormal (for example, falling), detecting that the user's sports equipment is abnormal, detecting that the user's location is within a preset area (for example, the user is in a high altitude area), etc.
[0408] The physiological data 1 can be used to determine the physiological parameter 1, which may include but is not limited to any one or more of the following: blood sugar, blood ketones, blood lactate, uric acid, etc.
[0409] Physiological data 1 may include, but is not limited to, any one or more of the following: current data, body temperature, a measured value of a physiological parameter 1, a calibrated value of a physiological parameter 1, and the like. The current data is used to characterize the magnitude of a reaction current generated by a reaction between an electrochemical electrode in the electronic device 200 and the target substance 1. The body temperature may be the body temperature of a user (or other organism) wearing the electronic device 200. The measured value of the physiological parameter 1 may be a value of the physiological parameter 1 determined by the electronic device 200 through a calculation model of the physiological parameter 1 based on the current data. The calibrated value of the physiological parameter 1 may be a value of the physiological parameter 1 determined by the electronic device 200 based on the current data and the body temperature, that is, a value of the physiological parameter 1 after calibration based on the body temperature.
[0410] The following describes a specific method in which the electronic device 100 determines whether the monitoring condition 3 is satisfied.
[0411] In some embodiments, the electronic device 100 may obtain user information and determine whether the electronic device 100 meets monitoring condition 3 based on the user information. The user information may include, but is not limited to, any one or more of the following: physiological information, psychological information, motion information, sports equipment information, posture information, location information, and interaction information. Among them, physiological information can be used to characterize the user's physiological state, and physiological information may include but is not limited to any one or more of the following: heart rate, body temperature, blood pressure, disease information, etc.; psychological information can be used to characterize the user's psychological state, and psychological information may include but is not limited to any one or more of the following: stress value, low mood, stable mood, high mood, being frightened, etc.; motion information can be used to characterize the user's motion state, and motion information may include but is not limited to any one or more of the following: swimming, diving, cycling, running, climbing, skipping rope, yoga, etc.; sports equipment information can be used to characterize the status of sports equipment, and sports equipment information may include but is not limited to any one or more of the following: oxygen remaining in the oxygen cylinder, weight of the smart backpack, and travel resistance of the bicycle, etc.; posture information can be used to characterize the user's body posture, and posture information may include but is not limited to any one or more of the following: falling, stepping on air, and being still, etc.; location information can be used to characterize the user's location, and location information may include but is not limited to any one or more of the following: user's geographic location, latitude and longitude information of the user's location, altitude information of the user's location, depth information of the user's location, etc.; interaction information may include interaction operations between the user and the electronic device 100, such as receiving an operation from the user to turn on the physiological monitoring function.
[0412] It should be noted that in the embodiment of the present application, the way in which the electronic device 100 obtains user information may include but is not limited to the following ways: the electronic device 100 detects user information, the electronic device 100 receives user information sent by other electronic devices, and the electronic device 100 receives and obtains user information in response to the user entering user information (such as disease information).
[0413] The following describes some methods for electronic devices 100 to detect user information provided by embodiments of the present application.
[0414] For example, the electronic device 100 can detect the user's motion information and posture information through devices such as gyroscope sensors and accelerometers; the electronic device 100 can detect the user's physiological information such as heart rate and blood pressure through devices such as PPG modules; the electronic device 100 can also collect the user's facial expressions through a camera, and determine the user's emotional state through algorithm models such as image analysis and facial expression analysis; the electronic device 100 can also determine the user's psychological information such as pressure value based on physiological information; the electronic device 100 can also detect the user's interaction information through a touch sensor; the electronic device 100 can detect the user's location information through a position sensor (such as a global positioning chip, etc.); the electronic device 100 can also detect the air pressure of the user's environment based on a pressure sensor, and determine the user's location information such as the altitude based on the air pressure value, and so on.
[0415] It will be understood that the embodiments herein are merely examples. In the embodiments of the present application, the electronic device 100 may include more, fewer, or different devices than those in the above-described embodiments. Moreover, the electronic device 100 may also collect user information through sensors or other devices that are different from those in the above-described embodiments. This application does not limit this.
[0416] The following describes some methods provided by the electronic device 100 in the embodiments of the present application for determining whether monitoring condition 3 is met based on user information.
[0417] If the electronic device 100 determines that any physiological information is abnormal, it determines that the monitoring condition is met. For example, the physiological information abnormality may include but is not limited to any one or more of the following: heart rate not falling within a preset heart rate range, blood pressure not falling within a preset blood pressure range, body temperature not falling within a preset body temperature range, etc.
[0418] As another example, the electronic device 100 can determine whether the physiological information meets any of the following conditions: the heart rate does not belong to the preset heart rate range, the blood pressure does not belong to the preset blood pressure range, the body temperature does not belong to the preset body temperature range, etc.; if the physiological information meets any of the above conditions, the electronic device 100 can determine that the user's physiological state is abnormal, that is, it determines that the monitoring conditions are met.
[0419] If the electronic device 100 determines that the motion information satisfies a preset motion state, the monitoring condition is determined to be satisfied. For example, the preset motion state may include, but is not limited to, any one or more of the following: diving state, mountain climbing state, cycling state, yoga state, swimming state, running state, etc.
[0420] If the electronic device 100 determines that the user's psychological state is abnormal based on the psychological information, the monitoring condition is determined to be met. For example, the abnormal psychological state includes but is not limited to any one or more of the following: the user is frightened, the user is depressed, the user is excited, etc.
[0421] If the electronic device 100 determines that the user is in a preset area based on the location information, the monitoring condition is determined to be met. The preset area may include but is not limited to any one or more of the following: a high altitude area, a deep water area, etc.
[0422] If the electronic device 100 determines that the user's body posture is abnormal based on the posture information, the monitoring condition is determined to be met. For example, the abnormal user's body posture includes but is not limited to any one or more of the following situations: the user falls, the user misses a step, etc.
[0423] If the electronic device 100 determines that the user's sports equipment is abnormal based on the sports equipment information, it is determined that the monitoring condition is met. Exemplarily, the abnormality of the user's sports equipment may include, but is not limited to, any one or more of the following: the oxygen remaining in the oxygen cylinder is lower than the preset oxygen amount, the bicycle's travel resistance is greater than the preset resistance, the weight of the smart backpack is greater than the preset weight, etc. It can be understood that the above embodiments are merely illustrative of various ways of determining whether monitoring condition 3 is met based on user information. In the embodiments of the present application, the electronic device 100 may also determine whether monitoring condition 3 is met based on various types of user information. The electronic device 100 may also determine whether monitoring condition 3 is met based on other information in the user information, and monitoring condition 3 may also include more, fewer, or different conditions than those in the above embodiments, and the present application does not limit them here.
[0424] S602. The electronic device 200 obtains physiological data 1.
[0425] In some embodiments, the electronic device 200 may start acquiring physiological data 1 in response to the information 3 .
[0426] In other embodiments, the electronic device 200 may also periodically obtain the physiological data 1 before receiving the information 3 .
[0427] The manner in which the electronic device 200 obtains the physiological data 1 may refer to the relevant contents of step S501 shown in FIG. 5A , and will not be described in detail here.
[0428] S603 . The electronic device 200 sends the physiological data 1 to the electronic device 100 .
[0429] In some embodiments, the electronic device 200 may send the physiological data 1 to the electronic device 100 in response to the information 3 .
[0430] In other embodiments, the electronic device 200 periodically sends the physiological data 1 to the electronic device 100 before receiving the information 3. In this case, the above step S602 may not be performed; in addition, the monitoring condition 3 may be used to trigger the electronic device 100 to perform the following step S605.
[0431] S604 . The electronic device 100 determines the physiological parameter 1 based on the physiological data 1 .
[0432] In some embodiments, if the physiological data 1 includes a measured value or a calibrated value of the physiological parameter 1 , the electronic device 100 may use the measured value or the calibrated value of the physiological parameter 1 as the value of the physiological parameter 1 .
[0433] In some embodiments, if the physiological parameter 1 includes a measured value of the physiological parameter 1 and body temperature, the electronic device 100 may calibrate the measured value of the physiological parameter 1 based on the body temperature and determine the calibrated value as the value of the physiological parameter 1.
[0434] In some embodiments, if the physiological data 1 includes current data, the electronic device 100 may determine the value of the physiological parameter 1 based on the current data. Alternatively, if the physiological data 1 also includes body temperature, the electronic device 100 may also determine the value of the physiological parameter 1 based on the current data and body temperature.
[0435] S605. The electronic device 100 outputs the physiological parameter 1.
[0436] In some embodiments, after determining the user's physiological parameter 1, the electronic device 100 may output the physiological parameter 1. The electronic device 100 may output the physiological parameter 1 in ways that include, but are not limited to, any one or more of the following: display screen display, voice announcement, vibration, flashing indicator light, etc. For a schematic diagram of the interface for outputting the physiological parameter 1 by the electronic device 100, reference may be made to the description of the embodiments shown in Figures 7C to 7F below, and will not be described in detail here.
[0437] In some embodiments, the electronic device 100 may output any one or more of the following while outputting the user's physiological parameter 1 (or after outputting the physiological parameter 1): evaluation results, value ranges, user status, historical curves, reference suggestions, etc. Among them, the evaluation results are used to characterize whether the user's physiological parameters are normal. The value range refers to the normal range of the user's physiological parameters. The user status refers to the user's current state, such as fasting state, non-fasting state, exercise state, high altitude state, sleep state, etc. The historical curve is used to characterize the relationship between the user's physiological parameters and time over the past period of time (for example, 30 minutes, 3 hours, 24 hours, etc.). Reference suggestions can be used to guide users to maintain or restore physiological parameters to the normal range.
[0438] In other embodiments, after determining the user's physiological parameter 1, the electronic device 100 may also send an output instruction to another electronic device. The output instruction may include the user's physiological parameter 1, and the output instruction may be used to instruct the electronic device to output the user's physiological parameter 1. Optionally, the output instruction may also include, but is not limited to, any one or more of the following: user status, value range, evaluation results, historical curves, reference suggestions, etc. The electronic device 100 may output any one or more of the above content based on the output instruction.
[0439] The following describes how to determine the evaluation results, value range, user status, historical curves, and reference suggestions.
[0440] The following describes how the user status is determined.
[0441] In some embodiments, the electronic device 100 can determine the user status based on the user information. The specific content of the user information can refer to the relevant description in the above step S501, which will not be repeated here. For example, the electronic device 100 can receive and determine the user status in response to the user's operation of setting the user status. For another example, the electronic device 100 can determine whether the user is in a motion state based on the user's motion information. For another example, the electronic device 100 can determine whether the user is in a high altitude state based on the user's location information, etc. It can be understood that the embodiment here is only an illustrative example of how the electronic device 100 can determine the user status based on the user information. In the embodiment of the present application, the electronic device 100 can also determine the user status based on other information in the user information, and the present application does not limit it here.
[0442] The following describes how to determine the value range.
[0443] The value interval may be the value interval of the physiological parameter stored in the electronic device 100. For example, Table 1 shows the value interval of the physiological parameter stored in the electronic device 100 provided in an embodiment of the present application.
[0444] Table 1
[0445] As shown in Table 1, the electronic device 100 may store value ranges for one or more physiological parameters. For example, the value range for blood glucose may be [3.9, 6.1], the value range for blood ketones may be [0.05, 0.3], and the value range for uric acid may be [0.18, 0.42]. The units of the above value ranges are all millimoles per liter (mmol / L).
[0446] It can be understood that the embodiment shown in Table 1 is only an example. In the embodiment of the present application, the electronic device 100 can also store more, fewer or different value ranges of physiological parameters than the embodiment shown in Table 1, and the value range of the physiological parameters can also be different from the above value ranges. This application does not limit this.
[0447] In other embodiments, the electronic device 100 may also store value ranges of physiological parameters under different user states. For example, Table 2 shows value ranges of physiological parameters under different user states stored in another electronic device 100 provided in an embodiment of the present application.
[0448] Table 2
[0449] As shown in Table 2, the electronic device 100 may store value ranges for one or more physiological parameters in different user states. For example, in the fasting state, the blood glucose value range may be [3.9, 6.1]; in the non-fasting state, the blood glucose value range may be [3.9, 8.99]; in the fasting state, the blood ketone value range may be [0.05, 0.3]; in the non-fasting state, the blood ketone value range may be [0.05, 0.5]; in the fasting state, the uric acid value range may be [0.18, 0.42]; in the non-fasting state, the uric acid value range may be [0.18, 0.5]. The unit of the above value ranges is millimole / liter (mmol / L).
[0450] It is understandable that the embodiment shown in Table 2 is only an example. In the embodiment of the present application, the electronic device 100 may also store more, fewer, or different value intervals of physiological parameters than the embodiment shown in Table 2, and the value intervals of the physiological parameters may also be different from the above value intervals. This application does not limit this. In addition, the user status may also include more, fewer, or different user status than the above embodiment. Moreover, in other embodiments, the electronic device 100 may also store the correspondence between factors such as user gender, age, and disease and the value interval, which is not limited in this application.
[0451] The electronic device 100 may determine the value range based on any one or more factors such as user status, user age, gender, etc.
[0452] The following describes how the evaluation results are determined.
[0453] In one possible implementation, the electronic device 100 may store the value ranges of the user's physiological parameters and determine the evaluation result based on the user's physiological parameter 1 and the value range of the corresponding physiological parameter. In another possible implementation, the electronic device 100 may also determine the value range of the user's physiological parameter to which the user currently belongs based on the correspondence between the value ranges and one or more factors such as the user's gender, age, and user status, and determine the evaluation result based on the calibrated value of the physiological parameter.
[0454] In some embodiments, the evaluation results may include normal and abnormal. When the physiological parameter 1 falls within the value range, the electronic device 100 may determine that the evaluation result is normal for the physiological parameter. When the physiological parameter 1 does not fall within the value range, the electronic device 100 may determine that the evaluation result is abnormal for the physiological parameter. Optionally, in the case where the evaluation result is abnormal, the evaluation result may be further subdivided into any one or more of the following: high, low, too high, too low, etc., which is not limited in this application.
[0455] In some embodiments, if the evaluation result is determined to be abnormal (or the evaluation result is determined to be abnormally high or too low, etc.), the electronic device 100 can output a warning. The output method of the warning may include but is not limited to any one or more of the following: display screen display, voice broadcast, vibration, flashing indicator light, etc.
[0456] The following describes how to determine the historical curve.
[0457] In some embodiments, the electronic device 100 may determine a historical curve of the physiological parameter based on the currently measured physiological parameter calibration value. In other embodiments, the electronic device 100 may also determine a historical curve of the physiological parameter based on the currently measured physiological parameter calibration value and previously measured physiological parameter calibration values. The electronic device 100 may store the measurement time of each physiological parameter calibration value, and the electronic device 100 may determine a historical curve of the physiological parameter based on different calibration values corresponding to different measurement times.
[0458] The following describes how reference recommendations are determined.
[0459] In one possible implementation, the electronic device 100 may determine a reference recommendation based on the evaluation result. For example, if the evaluation result is normal, the reference recommendation may be to advise the user to maintain their current lifestyle habits, or to increase exercise and maintain a good sleep and rest schedule. If the evaluation result is abnormal, the reference recommendation may be to advise the user to correct unhealthy lifestyle habits, reduce the intake of greasy foods, etc.
[0460] In another possible implementation, the electronic device 100 may also determine reference suggestions based on user information. For example, when the electronic device 100 determines based on user information that the user is in a high-altitude area, the reference suggestion may include "The oxygen in the current area is thin, so be careful to reduce strenuous exercise." For another example, when the electronic device 100 determines based on user information that the user has been in a fasting state for a duration greater than a certain period (such as 4 hours), the reference suggestion may include "You are currently hungry, please eat as soon as possible," etc. It will be understood that the embodiment here is merely an illustrative example of how the electronic device 100 can determine reference suggestions based on user information. In the embodiment of the present application, the electronic device 100 may also determine content different from the above-mentioned reference suggestions based on user information, and the present application does not limit this.
[0461] S606 . The electronic device 100 determines that the monitoring condition 4 is met, and sends information 4 to the electronic device 200 . The information 4 is used to request the electronic device 200 to send an electrocardiogram signal to the electronic device 100 .
[0462] In some embodiments, monitoring condition 4 may include but is not limited to any one or more of the following: receiving an operation by the user to turn on the ECG function, receiving a start-up instruction 2 sent by other electronic devices, detecting that the user's physiological state is abnormal (for example, blood sugar does not belong to the preset blood sugar value range, etc.), detecting that the user's psychological state is abnormal (for example, being frightened), detecting that the user is in motion, detecting that the user has insomnia, detecting that the user's body posture is abnormal (for example, falling), detecting that the user's sports equipment is abnormal, detecting that the user's location is within a preset area (for example, the user is in a high altitude area), etc.
[0463] The determination method of each condition in monitoring condition 4 can also refer to the relevant content in the above step S601, which will not be repeated here.
[0464] In other embodiments, monitoring condition 4 may be the same as monitoring condition 3, that is, when the electronic device 100 determines that monitoring condition 3 is satisfied, the electronic device 100 may execute the above step S602 and the following step S608.
[0465] S607. The electronic device 200 obtains an electrocardiogram signal.
[0466] In some embodiments, the electronic device 200 may start acquiring electrocardiographic signals in response to the information 4 .
[0467] In other embodiments, the electronic device 200 may also periodically acquire the electrocardiogram signal before receiving the information 4 .
[0468] The manner in which the electronic device 200 acquires the electrocardiogram signal may refer to the relevant contents of step S503 shown in FIG. 5A , which will not be described in detail here.
[0469] S608. The electronic device 200 sends an electrocardiogram signal to the electronic device 100.
[0470] In some embodiments, the electronic device 200 may send an electrocardiogram signal to the electronic device 100 in response to the information 4 .
[0471] In other embodiments, the electronic device 200 periodically sends an ECG signal to the electronic device 100 before receiving the information 4. In this case, the above step S608 may not be performed; in addition, in this case, the monitoring condition 4 may be used to trigger the electronic device 100 to perform the following step S609.
[0472] S609. The electronic device 100 outputs an electrocardiogram signal.
[0473] The electronic device 100 can output the ECG signal in one or more ways, such as display screen display, audio broadcast, vibration, and flashing indicator light.
[0474] The electronic device 100 can also output the ECG signal in the form of an ECG. Optionally, the electronic device 100 can also output one or more of the following contents after outputting the ECG (or while outputting the ECG): one or more ECG indicators, evaluation results of the ECG indicators, evaluation results of the ECG function, value ranges of the ECG indicators, user status, etc. The value range of the ECG indicator refers to the normal range of the ECG indicator. The user status refers to the current state of the user, such as resting state, exercise state, high altitude state, sleeping state, etc. The evaluation result of the ECG indicator is used to indicate whether the ECG indicator belongs to the preset value range of the ECG indicator. The evaluation result of the ECG function is used to indicate whether the user's heart function is normal.
[0475] Among them, the specific content and determination method of the ECG index can refer to the relevant description in step S504 shown in Figure 5A above; the value range of the ECG index can be pre-stored by the electronic device 100; the evaluation result of the ECG index can be determined based on the ECG index and the value range of the ECG index, and the specific method can refer to the relevant description in the above step S605; the evaluation result of the ECG function can be determined based on the evaluation results of one or more ECG indicators; the method for determining the user status can also refer to the relevant description in the above step S605, which will not be repeated here.
[0476] In some application scenarios, the physiological parameter 1 may be blood glucose, and the output interface diagram of blood glucose may refer to the following FIG. 7A to FIG. 7F .
[0477] For example, as shown in FIG7A , the electronic device 100 displays a health application interface 700 , which may include one or more items, such as a blood sugar item 701 , a blood pressure item, an electrocardiogram item 702 , a blood oxygen item, etc. Each item may be used to trigger the electronic device 100 to display a corresponding physiological parameter monitoring interface.
[0478] The electronic device 100 may receive and, in response to a user's click operation on the blood glucose entry 701 , display a blood glucose monitoring interface 710 as shown in FIG. 7B .
[0479] As shown in Figure 7B, the blood glucose monitoring interface 710 may include a measurement control 711 and a history control 712. The measurement control 711 may be used to trigger the electronic device 100 to determine and output the user's blood glucose, and the history control 712 may be used to trigger the electronic device 100 to display past blood glucose measurement records (including the measurement time and the user's blood glucose).
[0480] The electronic device 100 may receive and respond to a user's click operation on the measurement control 711 , and after determining the user's blood sugar based on the physiological data sent by the electronic device 200 , the electronic device 100 may display an output interface 720 as shown in FIG. 7C .
[0481] As shown in Figure 7C , output interface 720 may include a blood glucose indicator 721, which indicates the user's blood glucose level. Optionally, output interface 720 may also include, but is not limited to, any one or more of the following: an evaluation result 722, a value range 723, a user status 724, and a history curve control 725. Evaluation result 722 may indicate whether the user's blood glucose level is normal. As shown in Figure 7C , evaluation result 722 is a horizontal line, indicating that the user's blood glucose level falls within a preset value range, i.e., the user's blood glucose level is normal. In some embodiments, if the user's blood glucose level is greater than the preset value range, the evaluation result may be an upward arrow, and if the user's blood glucose level is less than the preset value range, the evaluation result may be a downward arrow. It should be understood that the display of evaluation result 722 shown in Figure 7C is merely an example. In the embodiments of this application, the evaluation result may also be represented using different symbols, text, etc., and this application is not limited thereto. Value range 723 indicates the reference range of the user's blood glucose level, i.e., the normal range of blood glucose levels for the user's current state. User status 724 may indicate the user's current state, such as whether they are fasting. In some embodiments, the value interval 723 may be different depending on the user status. The history curve control 725 may be used to trigger the electronic device 100 to display a history curve of blood glucose, which is used to represent the relationship between the user's blood glucose level and time over a period of time.
[0482] The electronic device 100 may receive and respond to a user click operation on the history curve control 725, and display the history curve interface 730 shown in FIG7D . Alternatively, the electronic device 100 may also receive and respond to a user swipe-up operation on the output interface 720, and display the history curve and other content shown in FIG7D on the output interface 720.
[0483] As shown in Figure 7D, the historical curve interface 730 may include a historical curve 731, and optionally, may further include a reference suggestion 732. The historical curve 731 can be used to characterize the relationship between the user's blood sugar level and time over the past period of time. The reference suggestion 732 can be used to guide the user to maintain or restore blood sugar to a normal range. For example, the reference suggestion 732 may include the text "Blood sugar is stable, please maintain". It will be understood that the reference suggestion 732 shown in Figure 7D is only an example. In the embodiment of the present application, the reference suggestion 732 may also adopt an output form different from the above-mentioned embodiment, and may also include more, less or different content than the above-mentioned embodiment, and the present application does not limit it here.
[0484] In other embodiments, the electronic device 100 can receive and respond to the user's click operation on the measurement control 711. After determining the user's blood sugar (i.e., blood sugar value) based on the physiological data, if the user's blood sugar is abnormal, the electronic device 100 can optionally display a warning interface 740 as shown in Figure 7E, or display an output interface 750 as shown in Figure 7F.
[0485] As shown in FIG7E , warning interface 740 may include a warning 741 and, optionally, a view result control 742. Warning 741 may be used to inform the user of abnormal blood sugar levels. For example, warning 741 may include the text "Low blood sugar, please eat soon!!" View result control 742 may be used to trigger electronic device 100 to display the blood sugar level.
[0486] The electronic device 100 may receive and display an output interface 750 as shown in FIG7F in response to a user clicking operation on the view result control 742. In some embodiments, the electronic device 100 may also display an output interface 750 as shown in FIG7F when it detects that the display duration of the warning interface 740 is greater than a preset duration (e.g., 10 seconds, 15 seconds, etc.).
[0487] As shown in Figure 7F, output interface 750 may include blood sugar 751, which may be the user's blood sugar value. Optionally, output interface 750 may also include, but is not limited to, any one or more of the following: evaluation result 752, value range 753, user status 754, and reference suggestions 755. Evaluation result 752 may indicate whether the user's blood sugar is normal. As shown in Figure 7F, evaluation result 752 is a downward arrow, which may indicate that the user's blood sugar value is below a preset value range, i.e., the user's blood sugar is abnormal. Value range 753 represents the user's blood sugar reference range, i.e., the range of blood sugar values that indicate a healthy user. User status 754 may indicate the user's current state, such as whether they are fasting. In some embodiments, value range 753 may vary depending on the user's state. Output interface 750 may also include reference suggestions 755, which may, for example, include the text "Low blood sugar, please eat soon!" It is understandable that in other embodiments, the output interface 750 may also display a historical curve of blood glucose (or a historical curve control), etc. The historical curve is used to characterize the relationship between the user's blood glucose value and time over a period of time in the past, and this application does not limit this.
[0488] It can be understood that the embodiments shown in Figures 7A to 7F above are just two examples. In the embodiments of the present application, the output physiological parameters may also be other physiological parameters (such as blood ketones, uric acid, etc.), and the device that outputs physiological parameters may also be the electronic device 200 or other electronic devices, and the content displayed in the output interface may also include more, less or different content than the above embodiments, and the present application does not limit this.
[0489] 7G-7J show schematic diagrams of a set of output interfaces of ECG signals provided in an embodiment of the present application.
[0490] For example, as shown in FIG7G , the electronic device 100 may display a health application interface 700, which may include one or more items, such as a blood sugar item 701, a blood pressure item, an electrocardiogram item 702, a blood oxygen item, etc. Each item may be used to trigger the electronic device 100 to display a corresponding physiological parameter monitoring interface.
[0491] The electronic device 100 may receive and, in response to a user's click operation on the ECG entry 702 , display an ECG monitoring interface 760 as shown in FIG7H .
[0492] 7H , the ECG monitoring interface 760 may include a measurement control 761 and a history control 762. The measurement control 761 may be used to trigger the electronic device 100 to determine and output the user's ECG signal, and the history control 762 may be used to trigger the electronic device 100 to display past ECG signal measurement records.
[0493] The electronic device 100 may receive and respond to a user's click operation on the measurement control 761 , and after determining the user's electrocardiogram based on the electrocardiogram signal sent by the electronic device 200 , the electronic device 100 may display an output interface 770 as shown in FIG. 7I .
[0494] As shown in FIG. 7I , the output interface 770 may include an electrocardiogram 771 , which may be a waveform diagram of an electrocardiogram signal.
[0495] In some embodiments, the electronic device 100 may also receive and respond to a user swipe-up operation on the output interface 770. As shown in FIG7J , the electronic device 100 may display any one or more of the following on the output interface 770: heart rate 772, heart rate evaluation result 773, amplitude 774, amplitude evaluation result 775, and user status 776. Among them, heart rate 772 indicates the user's heart rate; heart rate evaluation result 773 indicates whether the user's heart rate is normal; amplitude 774 indicates the amplitude of the ECG signal; amplitude evaluation result 775 indicates whether the amplitude of the ECG signal is normal; and user status 776 indicates the user's current state, such as resting state (or exercise state, etc.). The user's state may have a certain impact on the ECG signal. As shown in FIG7J , the heart rate evaluation result 773 and the amplitude evaluation result 775 are both horizontal lines, which can indicate that the user's ECG falls within a preset value range, that is, the user's ECG is normal. For other specific contents of the heart rate evaluation result 773 and the amplitude evaluation result 775, reference may be made to the relevant contents of the evaluation result 722 in the embodiment shown in FIG. 7C , which will not be repeated here.
[0496] It can be understood that the embodiment shown in Figures 7G-7J above is only an example. In the embodiment of the present application, the output interface of the ECG signal may also include more, less or different content than the above embodiment, such as ECG indicators such as P wave duration and QT interval, etc., which are not limited in the present application.
[0497] In some application scenarios, the electronic device 100 may also prompt the user to perform electrocardiogram monitoring when it detects that the value of the physiological parameter 1 is abnormal.
[0498] For example, taking the physiological parameter 1 as blood sugar as an example, FIG7K shows a prompt interface 780 of the electronic device 100 when blood sugar is abnormal.
[0499] As shown in Figure 7K, the prompt interface 780 may include a prompt 781, an approval control 782, and a rejection control 783. The prompt 781 may be used to prompt the user to perform ECG monitoring. The prompt 781 may include text, such as "Abnormal blood sugar is detected, it is recommended to turn on the ECG monitoring function". The approval control 782 may be used to trigger the electronic device 100 to send information 4 to the electronic device 200. Information 4 is used to request the electronic device 200 to send an ECG signal to the electronic device 100. Optionally, a countdown (for example, 5 seconds, 3 seconds, etc.) may also be displayed on the approval control 782. When the countdown ends and the electronic device 100 does not receive the user's operation, the electronic device 100 may send information 4 to the electronic device 200. The rejection control 783 can be used to trigger the electronic device 100 to stop displaying the prompt interface 780. Optionally, it can also trigger the electronic device 100 to output content such as the blood sugar calibration value.
[0500] The electronic device 100 may receive and, in response to the user clicking on the consent control 782, display an ECG monitoring interface 790 as shown in FIG7L . The ECG monitoring interface 790 is used to prompt the user that the electronic device 100 is acquiring an ECG signal. In some embodiments, after receiving the ECG signal transmitted by the electronic device 200, the electronic device 100 may display the output interface 770 as shown in FIG7I above.
[0501] It can be understood that the above Figures 7K-7L are only exemplary illustrations. When the value of physiological parameter 1 is abnormal, it can trigger the user to turn on ECG monitoring. In the embodiment of the present application, the electronic device 100 can also directly jump to the ECG monitoring interface when it detects that the value of physiological parameter 1 (such as blood sugar, blood ketones, etc.) is abnormal, and display the ECG signal after obtaining the ECG signal. This application does not limit this.
[0502] In other application scenarios, the electronic device 100 may have a micro-physical examination function. When the electronic device 100 detects that the user has turned on the micro-physical examination function, it may output one or more physiological parameters and electrocardiogram signals after determining the one or more physiological parameters and electrocardiogram signals.
[0503] For example, as shown in FIG7M , the electronic device 100 may display a micro-physical examination interface 800. The micro-physical examination interface 800 may include a physical examination control 801. The physical examination control 801 may be used to trigger the electronic device 100 to output one or more physiological parameters and an electrocardiogram (ECG) signal. Optionally, the micro-physical examination interface 800 may also display physical examination items. The physical examination items may be used to prompt the user of the items that the micro-physical examination function can monitor. For example, in the embodiment shown in FIG7M , the physical examination items may include ECG, blood sugar, and blood ketones. After the micro-physical examination function is turned on, the electronic device 100 may output ECG, blood sugar, and blood ketones.
[0504] Optionally, before displaying the micro-physical examination interface 800 , the electronic device 100 may further display an interface for the user to select physical examination items. The electronic device 100 may receive and respond to the user's operation of selecting a physical examination item and display the micro-physical examination interface 800 as shown in FIG. 7M .
[0505] Electronic device 100 can receive and respond to a user's click on physical examination control 801. After determining blood glucose, blood ketones, and an electrocardiogram (ECG) signal, electronic device 100 can display output interface 810 as shown in FIG7N . Output interface 810 can include an electrocardiogram (ECG) 811, as well as blood glucose values 812 and blood ketone values 813. Optionally, output interface 810 can also include, but is not limited to, any one or more of the following: ECG indicators, blood glucose value ranges, blood ketone value ranges, blood glucose assessment results, blood ketone assessment results, etc.
[0506] It can be understood that the embodiments shown in Figures 7M and 7N are only exemplary illustrations. The electronic device 100 can output one or more physiological parameters and electrocardiogram signals at the same time. In the embodiments of the present application, the items monitored by the micro-physical examination function may also be different from the above embodiments. The electronic device 100 can also output multiple physiological parameters at the same time. This application does not limit this.
[0507] The following introduces the functional modules of an electronic device 200 provided in an embodiment of the present application.
[0508] FIG8 shows a schematic diagram of functional modules of a measurement system 10 provided in an embodiment of the present application.
[0509] As shown in FIG8 , the electronic device 200 may include an electrochemical module 2001 , an electrocardiogram module 2002 , a data processing module 2003 , a communication module 2004 , etc. Optionally, it may also include any one or more of the following: a temperature module 2005 , a control module 2006 , an output module 2007 , etc. Among them:
[0510] The electrochemical module 2001 can obtain current data of one or more physiological parameters (e.g., blood glucose, blood ketones, blood lactate, uric acid, etc.). In some embodiments, the electrochemical module 2001 can receive and respond to the message N1 sent by the control module 2006 or the communication module 2004, and start to obtain current data of one or more physiological parameters specified in the message N1. The electrochemical module 2001 can send the current data to the data processing module 2003.
[0511] The ECG module 2002 can acquire ECG signals and send the ECG signals to the data processing module 2003. In some embodiments, the ECG signal can also be received and responded to the message N2 sent by the control module 2006 or the communication module 2004 to acquire the ECG signals.
[0512] The data processing module 2003 can determine one or more physiological parameters based on the current data transmitted by the electrochemical module 2001. In some embodiments, the data processing module 2003 can also determine ECG indices and / or an electrocardiogram based on the ECG signals transmitted by the ECG module 2002. In some embodiments, the data processing module 2003 can also calibrate the values of the physiological parameters based on the body temperature transmitted by the temperature module 2005. The data processing module 2003 can transmit any one or more of the physiological parameters, ECG indices, and ECG to the output module 2007 or the communication module 2004.
[0513] The communication module 2004 can receive data (e.g., one or more physiological parameters, ECG indicators, an ECG, etc.) sent by the data processing module 2003 and send the received data to the electronic device 100. In some embodiments, the communication module 2004 can receive and respond to information 1 sent by another electronic device (e.g., the electronic device 100) and send a message N1 to the electrochemical module 2001. Message N1 is used to instruct the electrochemical module 2001 to begin acquiring current data for the one or more physiological parameters specified in message N1. The communication module 2004 can also receive and respond to information 2 sent by another electronic device (e.g., the electronic device 100) and send a message N2 to the ECG module 2002. Message N2 is used to instruct the ECG module 2002 to begin acquiring ECG signals. In other embodiments, the communication module 2004 can also receive information 1 sent by another electronic device (e.g., the electronic device 100) and send this information 1 to the control module 2006. The communication module 2004 can also receive information 2 sent by another electronic device (e.g., the electronic device 100) and send this information 2 to the control module 2006.
[0514] The control module 2006 may also determine whether monitoring condition 1 or monitoring condition 2 is satisfied. When monitoring condition 1 is satisfied, the control module 2006 may send message N1 to the electrochemical module 2001, instructing the electrochemical module 2001 to begin acquiring current data for one or more physiological parameters specified in message N1. When monitoring condition 2 is satisfied, the control module 2006 may send message N2 to the electrochemical module 2001, instructing the electrocardiogram module 2002 to begin acquiring electrocardiogram signals. In some embodiments, monitoring condition 1 may include receiving message 1 sent by the communication module 2004, and monitoring condition 2 may include receiving message 2 sent by the communication module 2004.
[0515] The temperature module 2005 can measure the body temperature of a user or a living being and send the body temperature to the data processing module 2003 .
[0516] The output module 2007 can receive data sent by the data processing module 2003 (for example, one or more physiological parameters, electrocardiogram indicators, electrocardiogram, etc.) and output the received data in one or more ways such as voice broadcast, display screen, vibration, flashing indicator light, etc.
[0517] It can be understood that the embodiment shown in Figure 8 is only an example. In the embodiment of the present application, the electronic device 200 may also include more, fewer or different functional modules than the above embodiment, or the above multiple functional modules may be combined into one functional module, or any of the above functional modules may be split into multiple functional modules. This application does not limit this.
[0518] The following introduces the functional modules of a measurement system 10 provided in an embodiment of the present application.
[0519] FIG9 shows a schematic diagram of functional modules of a measurement system 10 provided in an embodiment of the present application.
[0520] As shown in Figure 9, the measurement system 10 may include an electronic device 100 and an electronic device 200. The electronic device 100 may include a communication module 1002, a data processing module 1003, an output module 1006, etc. Optionally, the electronic device 100 may also include, but is not limited to, any one or more of the following: an interaction module 1001, a user information module 1004, and an evaluation module 1005. The electronic device 200 may include an electrochemical module 2001, an electrocardiogram module 2002, and a communication module 2004. Optionally, the electronic device 200 may also include any one or more of the following: a temperature module 2005, a control module 2006, etc.
[0521] The interaction module 1001 can receive and respond to user operations, such as an operation to enable the physiological monitoring function, an operation to enable the electrocardiogram function, etc. In response to the user's operation to enable the physiological monitoring function, the interaction module 1001 can send a message N3 to the communication module 1002. The message N3 can be used to instruct the communication module 1002 to send a message 3 to the electronic device 200. The message 3 is used to request the acquisition of physiological data of one or more specified physiological parameters.
[0522] The communication module 1002 can communicate with other electronic devices (such as the electronic device 200). In some embodiments, the communication module 1002 can receive and send information 3 to the communication module 2004 in the electronic device 200 in response to the message N3, and the information 3 is used to request the acquisition of physiological data. The communication module 1002 can also receive physiological data sent by the communication module 2004 in the electronic device 200, and send the physiological data to the data processing module 1003. In some embodiments, the communication module 1002 can also receive physiological parameters (i.e., the values of physiological parameters) sent by the data processing module 1003, as well as receive the evaluation results and / or reference suggestions sent by the evaluation module 1005, and send any one or more of the physiological parameters, evaluation results, and reference suggestions to other electronic devices.
[0523] The data processing module 1003 can determine physiological parameters, such as blood glucose and blood ketones, based on the physiological data sent by the communication module 1002. After determining the physiological parameters, the data processing module 1003 can send the physiological parameters to the output module 1006 or the communication module 1002. In some embodiments, the data processing module 1003 can also send the physiological parameters to the evaluation module 1005.
[0524] The user information module 1004 can obtain user information. In some embodiments, the user information module 1004 can collect user information. In other embodiments, the user information module 1004 can receive user information obtained by the communication module 1002 from other electronic devices. In some embodiments, the user information module 1004 can determine the user status based on the user information and send the user status to the evaluation module 1005. In some embodiments, the user information module 1004 can also determine whether the user information meets monitoring conditions (e.g., monitoring condition 3, monitoring condition 4, etc.). If monitoring condition 3 is met, the user information module 1004 can send a message N4 to the communication module 1002. Message N4 can be used to instruct the communication module 1002 to send information 3 to the electronic device 200. If monitoring condition 4 is met, the user information module 1004 can send a message N5 to the communication module 1002. Message N5 can be used to instruct the communication module 1002 to send information 4 to the electronic device 200.
[0525] The evaluation module 1005 may store a value interval of a physiological parameter. The evaluation module 1005 may determine an evaluation result based on the value interval of the physiological parameter and the physiological parameter, and the evaluation result is used to indicate whether the physiological parameter is normal. In some embodiments, the evaluation module 1005 may also receive the user status sent by the user information module 1004, and determine the evaluation result based on the relationship between the user status and the value interval of the physiological parameter, and the physiological parameter. In other embodiments, the evaluation module 1005 may also determine a reference suggestion based on the user status and / or the evaluation result, and the reference suggestion is used to guide the user to maintain (or restore to) a normal range for the physiological parameter. The evaluation module 1005 may send the evaluation result and / or the reference suggestion to the output module 1006, or send it to other electronic devices through the communication module 1002.
[0526] The output module 1006 can receive and output the physiological parameters sent by the data processing module 1003, and can also receive and output the evaluation results and / or reference suggestions sent by the evaluation module 1005, etc.
[0527] In electronic device 200, communication module 2004 can communicate with electronic device 100. In some embodiments, communication module 2004 can receive message 3 sent by communication module 1002 and send message 3 to control module 2006 or message N6 to electrochemical module 2001. Message N6 instructs electrochemical module 2001 to send current data of one or more specified physiological parameters to communication module 2004. In some embodiments, communication module 2004 can receive message 4 sent by communication module 1002 and send message 4 to control module 2006 or message N7 to electrocardiogram module 2002. Message N7 instructs electrocardiogram module 2002 to send electrocardiogram signals to communication module 2004.
[0528] The electrochemical module 2001 can obtain current data of one or more physiological parameters (e.g., blood glucose, blood ketones, blood lactate, uric acid, etc.). In some embodiments, the electrochemical module 2001 can receive and respond to message N6 sent by the control module 2006 or the communication module 2004, and begin obtaining current data of the one or more physiological parameters specified in message N6. In other embodiments, the electrochemical module 2001 can send current data of the one or more physiological parameters to the communication module 2004 in response to message N6 sent by the control module 2006 or the communication module 2004.
[0529] ECG module 2002 can acquire ECG signals. In some embodiments, ECG module 2002 can also receive ECG signals and start acquiring ECG signals in response to message N7 sent by control module 2006 or communication module 2004. In other embodiments, ECG module 2002 can send ECG signals to communication module 2004 in response to message N7 sent by control module 2006 or communication module 2004.
[0530] The control module 2006 may also determine whether monitoring condition 1 or monitoring condition 2 is satisfied. When monitoring condition 1 is satisfied, the control module 2006 may send message N1 to the electrochemical module 2001, instructing the electrochemical module 2001 to begin acquiring current data for one or more physiological parameters specified in message N1. When monitoring condition 2 is satisfied, the control module 2006 may send message N2 to the electrochemical module 2001, instructing the ECG module 2002 to begin acquiring ECG signals. In some embodiments, monitoring condition 1 may include receiving message 3 sent by the communication module 2004, and monitoring condition 2 may include receiving message 4 sent by the communication module 2004.
[0531] The temperature module 2005 may measure the body temperature of a user or a living being and transmit the body temperature to the communication module 2004 .
[0532] In other embodiments, the electronic device 200 may further include, but is not limited to, any one or more of the following: a data processing module, an evaluation module, an output module, etc. The functional description of the one or more modules can refer to the functional description of the relevant modules in the embodiment shown in Figure 8 or Figure 9 above, and will not be repeated here. It should be noted that if the electronic device 200 includes a data processing module, the physiological data sent by the communication module 2004 to the electronic device 100 may also refer to the value of a physiological parameter (e.g., a measured value of a physiological parameter or a calibrated value of a physiological parameter).
[0533] It can be understood that the embodiment shown in Figure 9 is only an example. In the embodiment of the present application, the measurement system 10 may include more, fewer or different functional modules than the above embodiment, or the above multiple functional modules may be combined into one functional module, or any of the above functional modules may be split into multiple functional modules. The present application does not limit this.
[0534] It should be noted that the measurement method provided in the embodiment of the present application can not only measure the physiological parameters and electrocardiogram signals of the user, but also measure the physiological parameters and electrocardiogram signals of other organisms (such as pets, poultry, livestock, endangered animals, etc.), and this application does not limit this.
[0535] For the convenience of subsequent description, the above-mentioned electronic device 100 and electronic device 200 can be collectively referred to as devices. It should be understood that the division of the various units in the device is only a division of logical functions. In actual implementation, they can be fully or partially integrated into one physical entity, or they can be physically separated. In addition, the units in the device can be implemented in the form of a processor calling software; for example, the device includes a processor, the processor is connected to a memory, the memory stores instructions, and the processor calls the instructions stored in the memory to implement any of the above methods or implement the functions of the various units of the device, wherein the processor is, for example, a general-purpose processor, such as a central processing unit (CPU) or a microprocessor, and the memory is a memory within the device or a memory outside the device. Alternatively, the units in the device can be implemented in the form of hardware circuits, and the functions of some or all of the units can be realized by designing the hardware circuits. The hardware circuit can be understood as one or more processors. For example, in one implementation, the hardware circuit is an application-specific integrated circuit (ASIC), which realizes the functions of some or all of the above units by designing the logical relationship of the components in the circuit. For another example, in another implementation, the hardware circuit can be implemented by a programmable logic device (PLD). Taking a field programmable gate array (FPGA) as an example, it can include a large number of logic gate circuits, and the connection relationship between the logic gate circuits is configured by configuring the configuration file, thereby realizing the functions of some or all of the above units. All units of the above devices can be implemented in the form of software called by the processor, or in the form of hardware circuits, or in part by software called by the processor, and the rest by hardware circuits.
[0536] In an embodiment of the present application, a processor is a circuit with data processing capabilities. In one implementation, the processor can be a circuit with instruction reading and execution capabilities, such as a CPU, a microprocessor, a graphics processing unit (GPU) (which can be understood as a microprocessor), or a digital signal processor (DSP); in another implementation, the processor can implement certain functions through the logical relationship of a hardware circuit, and the logical relationship of the hardware circuit is fixed or reconfigurable, such as a hardware circuit implemented by an ASIC or PLD, such as an FPGA. In a reconfigurable hardware circuit, the process of the processor loading a configuration document and implementing the hardware circuit configuration can be understood as the process of the processor loading instructions to implement the functions of some or all of the above units. In addition, it can also be a hardware circuit designed for artificial intelligence, which can be understood as an ASIC, such as a neural network processing unit (NPU), a tensor processing unit (TPU), a deep learning processing unit (DPU), etc.
[0537] It can be seen that each unit in the above device can be one or more processors (or processing circuits) configured to implement the above method, such as: CPU, GPU, NPU, TPU, DPU, microprocessor, DSP, ASIC, FPGA, or a combination of at least two of these processor forms.
[0538] In addition, the various units in the above devices can be fully or partially integrated together, or can be implemented independently. In one implementation, these units are integrated together and implemented in the form of a system-on-a-chip (SOC). The SOC may include at least one processor for implementing any of the above methods or implementing the functions of the various units of the device. The type of the at least one processor can be different, for example, including a CPU and FPGA, a CPU and an artificial intelligence processor, a CPU and a GPU, etc.
[0539] A possible physical structure of the electronic device 300 provided in an embodiment of the present application is introduced below.
[0540] For example, FIG10 shows a schematic diagram of the physical structure of an electronic device 300 provided in an embodiment of the present application.
[0541] As shown in Figure 10, electronic device 300 can be any of electronic device 100 and electronic device 200 in the above embodiments. Electronic device 300 may include: a processor 1101 and a memory 1102, and optionally, a transmitter 1103 and a receiver 1104. The processor 1101, memory 1102, transmitter 1103, and receiver 1104 may be interconnected or connected to each other via a bus 1105.
[0542] Exemplarily, the memory 1102 is used to store computer programs and data of the electronic device 300. The memory 1102 may include, but is not limited to, random access memory (RAM), read-only memory (ROM), erasable programmable read-only memory (EPROM), or portable read-only memory (CD-ROM).
[0543] The software or program codes required for all or part of the functions of the electronic device 300 in the above method embodiment are stored in the memory 1102 .
[0544] In one possible implementation, if the software or program code required for some functions is stored in the memory 1102, the processor 1101, in addition to calling the program code in the memory 1102 to implement some functions, can also cooperate with other components (such as the transmitter 1103 and the receiver 1104, etc.) to jointly complete other functions described in the method embodiment (such as the function of receiving or sending data).
[0545] The transmitter 1103 and the receiver 1104 are used to support the electronic device 300 to communicate, such as receiving or sending data or signals.
[0546] For example, the processor 1101 may be the CPU, GPU, NPU, TPU, DPU, microprocessor, DSP, ASIC, FPGA, or a combination of at least two of these processor types, as described above. The processor 1101 may be configured to read the program stored in the memory 1102 and execute the operations performed by the electronic device 300 in any of the above embodiments.
[0547] The specific operations and beneficial effects of each unit in the electronic device 300 shown in FIG10 can be found in the corresponding description in the above method embodiment, which will not be repeated here.
[0548] It can be understood that the embodiment shown in Figure 10 is only an example. In the embodiment of the present application, the electronic device 300 may also include more, fewer or different devices than the embodiment shown in Figure 10 above, and the present application does not limit this.
[0549] The following introduces a chip system provided by an embodiment of the present application.
[0550] The present application also provides a chip system, which includes at least one processor for implementing the functions involved in any side of the electronic device 100 or the electronic device 200 in any of the above embodiments.
[0551] In one possible design, the chip system further includes a memory, which is used to store program instructions and data, and the memory is located inside or outside the processor.
[0552] The chip system can be composed of chips, or can include chips and other discrete devices.
[0553] Optionally, there may be one or more processors in the chip system. The processor may be implemented in hardware or software. When implemented in hardware, the processor may be a logic circuit, an integrated circuit, etc. When implemented in software, the processor may be a general-purpose processor implemented by reading software code stored in a memory.
[0554] Optionally, the memory in the chip system may be one or more. The memory may be integrated with the processor or may be provided separately from the processor, which is not limited in the embodiments of the present application. For example, the memory may be a non-transient processor, such as a read-only memory (ROM), which may be integrated with the processor on the same chip or provided on different chips. The embodiments of the present application do not specifically limit the type of memory or the configuration of the memory and the processor.
[0555] Exemplarily, the chip system may be a field programmable gate array (FPGA), an application specific integrated circuit (ASIC), a system on chip (SoC), a central processor unit (CPU), a network processor (NP), a digital signal processor (DSP), a micro controller unit (MCU), a programmable logic device (PLD) or other integrated chips.
[0556] It can be understood that the above chip system is only an example. In the embodiments of the present application, the chip system may also include more, fewer or different devices than the above embodiments, and the present application does not limit this.
[0557] FIG11 shows a flow chart of a measurement method provided in an embodiment of the present application.
[0558] As shown in FIG11 , the specific process of the measurement method may include the following steps:
[0559] S1101. When the first electrode group and the second electrode group are implanted in subcutaneous tissue, the first electronic device determines the first physiological parameter through the first electrode group; the first electronic device includes the first electrode group and the second electrode group, and the distance between the first electrode group and the second electrode group is greater than the first distance.
[0560] The first electronic device may be the electronic device 200 in the above embodiment. The first electrode group may be the electrode group 1 in the above embodiment, and the second electrode group may be the electrode group 2 in the above embodiment.
[0561] The first distance may be a preset distance, such as three centimeters. When the distance between the first electrode group and the second electrode group is greater than the first distance, the first electrode group and the second electrode group may measure the electrocardiogram signal.
[0562] In a possible implementation, the first physiological parameter may include, but is not limited to, any one or more of the following: blood glucose, blood ketones, uric acid, blood lactate, etc.
[0563] The specific manner in which the first electronic device determines the first physiological parameter through the first electrode group can refer to the relevant description in the embodiment shown in FIG5A above, and will not be repeated here.
[0564] In one possible implementation, the first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode; the first pair of electrodes forms a loop with the first working electrode; determining the first physiological parameter through the first electrode group specifically includes: determining the first physiological parameter through the first working electrode and the first pair of electrodes; determining the electrocardiogram signal through the first electrode group and the second electrode group specifically includes: determining the electrocardiogram signal through the first working electrode and the second working electrode, or determining the electrocardiogram signal through the first pair of electrodes and the second working electrode.
[0565] In this way, the first electrode group can form a two-electrode system, through which the first physiological parameter can be measured. The first working electrode (or first pair of electrodes) in the first electrode group and any electrode in the second electrode group can serve as the LA electrode and RA electrode, respectively, to measure the electrocardiogram signal.
[0566] In one possible implementation, the first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode; the first pair of electrodes and the first working electrode form a loop; the first working electrode or the first pair of electrodes is connected to the right leg drive circuit; determining the first physiological parameter through the first electrode group specifically includes: determining the first physiological parameter through the first working electrode and the first pair of electrodes; determining the electrocardiogram signal through the first electrode group and the second electrode group specifically includes: determining the electrocardiogram signal through the first working electrode, the first pair of electrodes, and the second working electrode.
[0567] The electrode connected to the right leg drive circuit can serve as the right leg drive RLD electrode. The right leg drive circuit can be used to offset common-mode signals. The specific circuit composition of the right leg drive circuit can be referenced in the above-mentioned FIG. 4C and other embodiments, and will not be further described here.
[0568] In this way, the first electrode group can form a two-electrode system, through which the first physiological parameter can be measured. The first working electrode, the first pair electrode in the first electrode group, and any electrode in the second electrode group can be used as the LA electrode, the RLD electrode, and the RA electrode, respectively, to measure the electrocardiogram signal.
[0569] In one possible implementation, the first electrode group includes a first working electrode, a first reference electrode and a first pair of electrodes; the first reference electrode is used to control the voltage of the first working electrode, and the first pair of electrodes forms a loop with the first working electrode; determining the first physiological parameter through the first electrode group specifically includes: generating a first current through the first working electrode; and determining the first physiological parameter based on the first current.
[0570] In this way, the first electrode group can constitute a three-electrode system, through which the first current is generated and conducted.
[0571] In one possible implementation, the second electrode group includes a second working electrode, a second reference electrode and a second pair of electrodes; the second reference electrode is used to control the voltage of the second working electrode, and the second pair of electrodes is used to form a loop with the second working electrode; the method also includes: generating a second current through the second working electrode; and determining a second physiological parameter based on the second current.
[0572] In this way, the second electrode group can constitute a three-electrode system, through which the second current is generated and conducted.
[0573] For example, taking the embodiments shown in FIG. 4C to FIG. 4J above as an example, in the above embodiments, the first working electrode may be the working electrode W1, the second working electrode may be the working electrode W2, the first counter electrode may be the counter electrode C1, the second counter electrode may be the counter electrode C2, the first reference electrode may be the reference electrode R1, and the second reference electrode may be the reference electrode R2.
[0574] S1102. The first electronic device determines an electrocardiogram signal through the first electrode group and the second electrode group.
[0575] In a possible implementation, determining the electrocardiogram signal through the first electrode group and the second electrode group specifically includes: determining the electrocardiogram signal through any electrode in the first electrode group and any electrode in the second electrode group.
[0576] The left arm electrode and the right arm electrode can be selected from one electrode in the first electrode group and one electrode in the second electrode group, respectively. In this way, the electrocardiogram signal can be measured through the left arm electrode and the right arm electrode.
[0577] In one possible implementation, determining the ECG signal through the first electrode group and the second electrode group specifically includes: determining the ECG signal through any two electrodes in the first electrode group and any one electrode in the second electrode group; or determining the ECG signal through any one electrode in the first electrode group and any two electrodes in the second electrode group.
[0578] The left arm electrode and the right arm electrode can be selected from one electrode in the first electrode group and one electrode in the second electrode group, respectively. The right leg drive electrode can be an electrode in the first electrode group or an electrode in the second electrode group. In this way, ECG signals can be measured using the left arm electrode, the right arm electrode, and the right leg drive electrode. The right leg drive electrode is used to cancel common-mode signals through the right leg drive circuit.
[0579] In this way, the electrochemical electrodes in the first electrode group can be used to measure both the first physiological parameter and the electrocardiogram signal.
[0580] In one possible implementation, the ECG signal is determined by any two electrodes in the first electrode group and any one electrode in the second electrode group, specifically including: when the first pair of electrodes is connected to the right leg drive circuit, the ECG signal is determined by the first pair of electrodes, the first working electrode and the second reference electrode.
[0581] In one possible implementation, the ECG signal is determined by any one electrode in the first electrode group and any two electrodes in the second electrode group, specifically including: when the second pair of electrodes is connected to the right leg drive circuit, the ECG signal is determined by the second pair of electrodes, the second working electrode and the first reference electrode.
[0582] It should be noted that the above two implementation methods are just two examples. In this application, other electrodes in the first electrode group and the second electrode group can also be selected to measure the electrocardiogram signal, and this application does not limit this.
[0583] In one possible implementation, the first electrode group also includes a first ECG electrode and a second ECG electrode, the second electrode group also includes a third ECG electrode, and the second ECG electrode is connected to the right leg drive circuit; determining the ECG signal through the first electrode group and the second electrode group specifically includes: determining the ECG signal through the first ECG electrode, the second ECG electrode, and the third ECG electrode.
[0584] In this way, ECG signals can be measured through the separately provided ECG electrodes.
[0585] By using the measurement method provided in the embodiment of the present application, the user's electrocardiogram signal can be measured anytime and anywhere, and physiological parameters such as blood sugar, blood ketones, blood lactate, uric acid, etc. can also be measured.
[0586] In a possible implementation, the first electronic device further includes a first microneedle sensor and a second microneedle sensor, the first microneedle sensor includes a first electrode group, and the second microneedle sensor includes a second electrode group.
[0587] For example, the first microneedle sensor may be the microneedle sensor 303 shown in FIG. 3A-FIG . 3B , and the second microneedle sensor may be the microneedle sensor 304 shown in FIG. 3A-FIG . 3B .
[0588] In some embodiments, a microneedle sensor may be a sensor having a shape similar to a microneedle, and a plurality of electrodes may be disposed inside the microneedle sensor. Thus, a first electrode group and a second electrode group may be disposed in the microneedle sensor.
[0589] In a possible implementation, the first electronic device further includes a first array sensor and a second array sensor, the first array sensor includes a first electrode group, and the second array sensor includes a second electrode group.
[0590] In some embodiments, an array sensor may refer to a sensor including a plurality of electrodes arranged in an array.
[0591] Exemplarily, the first array sensor may be the array sensor 307 shown in FIG. 3D to FIG. 3E , and the second array sensor may be the array sensor 308 shown in FIG. 3D to FIG. 3E .
[0592] In this way, the first electrode group and the second electrode group can be respectively arranged in the array sensor in the form of an array.
[0593] In a possible implementation, the first electronic device further includes a first microneedle sensor and a second array sensor, the first microneedle sensor includes a first electrode group, and the second array sensor includes a second electrode group.
[0594] In this way, the first electrode group can be provided in a microneedle sensor, and the second electrode group can be provided in an array sensor in an array form.
[0595] In one possible implementation, before determining the first physiological parameter through the first electrode group, the method also includes: determining that a first condition is satisfied, the first condition including any one or more of the following: receiving first information sent by the second electronic device, the first information is used to instruct the first electronic device to determine the first physiological parameter; detecting that the first electrode group and the second electrode group are implanted in subcutaneous tissue; detecting an abnormal electrocardiogram signal.
[0596] In this way, the first condition may be a trigger condition for measuring the first physiological parameter.
[0597] The first condition may be the monitoring condition 1 in the embodiment shown in FIG. 5A .
[0598] In one possible implementation, before determining the electrocardiogram signal through the first electrode group and the second electrode group, the method also includes: determining that a second condition is satisfied, the second condition including any one or more of the following: receiving second information sent by a second electronic device, the second information being used to instruct the first electronic device to determine the electrocardiogram signal; detecting that the first electrode group and the second electrode group are implanted in subcutaneous tissue; detecting that the first physiological parameter does not belong to the first interval.
[0599] In this way, the second condition may be a trigger condition for determining an electrocardiogram signal.
[0600] The second condition may be the monitoring condition 2 in the embodiment shown in FIG. 5A .
[0601] In a possible implementation, after determining the first physiological parameter through the first electrode group, the method further includes: outputting the first physiological parameter, or sending the first physiological parameter to a second electronic device.
[0602] In this way, the first physiological parameter can be output, or the first physiological parameter can be output through other electronic devices.
[0603] In a possible implementation, after the electrocardiogram signal is determined by the first electrode group and the second electrode group, the method further includes: outputting the electrocardiogram signal, or sending the electrocardiogram signal to a second electronic device.
[0604] In this way, the ECG signal can be output, or the ECG signal can be output through other electronic devices.
[0605] The second electronic device may be the electronic device 100 in the above embodiment.
[0606] The specific method of outputting the first physiological parameter and the electrocardiogram signal can refer to the relevant content in the embodiments shown in Figures 5A and 7A to 7N above, and will not be repeated here.
[0607] The various implementation modes of this application can be combined arbitrarily to achieve different technical effects.
[0608] In the above embodiments, all or part of the embodiments may be implemented by software, hardware, firmware, or any combination thereof. When implemented using software, all or part of the embodiments may be implemented in the form of a computer program product. The computer program product includes one or more computer instructions. When the computer program instructions are loaded and executed on a computer, all or part of the processes or functions described herein are generated. The computer may be a general-purpose computer, a special-purpose computer, a computer network, or other programmable device. The computer instructions may be stored in a computer-readable storage medium or transmitted from one computer-readable storage medium to another. For example, the computer instructions may be transmitted from one website, computer, server, or data center to another website, computer, server, or data center via a wired (e.g., coaxial cable, optical fiber, digital subscriber line) or wireless (e.g., infrared, wireless, microwave, etc.) method. The computer-readable storage medium may be any available medium that a computer can access or a data storage device such as a server or data center that includes one or more available media integrated therein. The available medium may be a magnetic medium (e.g., a floppy disk, a hard disk, a tape), an optical medium (e.g., a DVD), or a semiconductor medium (e.g., a solid-state drive (SSD)).
[0609] Those skilled in the art will appreciate that all or part of the process steps in the above-described method embodiments can be implemented by a computer program instructing the relevant hardware. The program can be stored in a computer-readable storage medium, and when executed, the program can include the process steps in the above-described method embodiments. The aforementioned storage medium includes various media capable of storing program code, such as ROM or random access memory (RAM), magnetic disks, or optical disks.
[0610] In short, the above description is only an embodiment of the technical solution of the present invention and is not intended to limit the scope of protection of the present invention. Any modifications, equivalent replacements, improvements, etc. made based on the disclosure of the present invention should be included in the scope of protection of the present invention.
Claims
1. A measurement method, characterized in that, Applied to a first electronic device, the first electronic device includes a first electrode group and a second electrode group, and the distance between the first electrode group and the second electrode group is greater than a first distance; When the first electrode group and the second electrode group are implanted into subcutaneous tissue, the method includes: Determining a first physiological parameter through the first electrode group; Determining an electrocardiogram signal through the first electrode group and the second electrode group.
2. The method according to claim 1, characterized in that, The first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode; the first pair of electrodes forms a loop with the first working electrode; the first working electrode or the first pair of electrodes is connected to a right leg drive circuit; The determining of the first physiological parameter through the first electrode group specifically includes: Determining the first physiological parameter through the first working electrode and the first pair of electrodes; The determining of the electrocardiogram signal through the first electrode group and the second electrode group specifically includes: Determining the electrocardiogram signal through the first working electrode, the first pair of electrodes and the second working electrode.
3. The method according to claim 1, characterized in that The first electrode group includes a first working electrode, a first reference electrode and a first pair of electrodes; the first reference electrode is used to control the voltage of the first working electrode, and the first pair of electrodes forms a loop with the first working electrode; The determining of the first physiological parameter through the first electrode group specifically includes: Generating a first current through the first working electrode; Determining the first physiological parameter based on the first current.
4. The method according to claim 3, wherein The second electrode group includes a second working electrode, a second reference electrode and a second pair of electrodes; The second reference electrode is used to control the voltage of the second working electrode, and the second pair of electrodes is used to form a loop with the second working electrode; the method further includes: Generating a second current through the second working electrode; Determining the second physiological parameter based on the second current.
5. The method according to claim 4, wherein The determining of the electrocardiogram signal through the first electrode group and the second electrode group specifically includes: Determining the electrocardiogram signal through any two electrodes in the first electrode group and any one electrode in the second electrode group; Or, Determining the electrocardiogram signal through any one electrode in the first electrode group and any two electrodes in the second electrode group.
6. The method according to claim 5, characterized in that Determining the electrocardiogram signal through any two electrodes in the first electrode group and any one electrode in the second electrode group specifically includes: When the first pair of electrodes is connected to a right leg drive circuit, determining the electrocardiogram signal through the first pair of electrodes, the first working electrode and the second reference electrode.
7. The method according to claim 3 or 4, characterized in that, The first electrode group further includes a first electrocardiogram electrode and a second electrocardiogram electrode, and the second electrode group further includes a third electrocardiogram electrode, and the second electrocardiogram electrode is connected to a right leg drive circuit; The determining of the electrocardiogram signal through the first electrode group and the second electrode group specifically includes: Determining the electrocardiogram signal through the first electrocardiogram electrode, the second electrocardiogram electrode and the third electrocardiogram electrode.
8. The method according to any one of claims 1-7, characterized in that, The first electronic device further includes a first microneedle sensor and a second microneedle sensor, the first microneedle sensor includes the first electrode group, and the second microneedle sensor includes the second electrode group.
9. The method according to any one of claims 1-7, characterized in that, The first electronic device further includes a first array sensor and a second array sensor. The first array sensor includes the first electrode group, and the second array sensor includes the second electrode group.
10. The method according to any one of claims 1-9, characterized in that, Before determining the first physiological parameter through the first electrode group, the method further includes: Determining that a first condition is met, where the first condition includes any one or more of the following: receiving a first message sent by a second electronic device, the first message being used to instruct the first electronic device to determine the first physiological parameter; detecting that the first electrode group and the second electrode group are implanted into subcutaneous tissue; detecting an abnormal electrocardiogram signal.
11. The method according to any one of claims 1 to 10, characterized in that, Before determining the electrocardiogram signal through the first electrode group and the second electrode group, the method further includes: Determining that a second condition is met, where the second condition includes any one or more of the following: receiving a second message sent by a second electronic device, the second message being used to instruct the first electronic device to determine the electrocardiogram signal; detecting that the first electrode group and the second electrode group are implanted into subcutaneous tissue; detecting that the first physiological parameter does not belong to a first interval.
12. The method according to any one of claims 1-11, characterized in that, After determining the first physiological parameter through the first electrode group, the method further includes: Outputting the first physiological parameter, or sending the first physiological parameter to a second electronic device.
13. The method according to any one of claims 1 to 12, characterized in that, After determining the electrocardiogram signal through the first electrode group and the second electrode group, the method further includes: Outputting the electrocardiogram signal, or sending the electrocardiogram signal to a second electronic device.
14. The method according to any one of claims 1-13, characterized in that, The first physiological parameter includes any one or more of the following: blood glucose, blood ketone, uric acid, blood lactic acid.
15. An electronic device, being a first electronic device, characterized in that, Including a first electrode group and a second electrode group, the distance between the first electrode group and the second electrode group is greater than a first distance; The first electrode group is used to determine a first physiological parameter when the first electrode group is implanted into subcutaneous tissue; The second electrode group is used to determine a second physiological parameter when the second electrode group is implanted into subcutaneous tissue; The first electrode group and the second electrode group are further used to determine an electrocardiogram signal when the first electrode group and the second electrode group are implanted into subcutaneous tissue.
16. The electronic device according to claim 15, characterized in that, The first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode and a second pair of electrodes; the first pair of electrodes forms a loop with the first working electrode, and the second pair of electrodes forms a loop with the second working electrode; The first electrode group is used to determine a first physiological parameter when the first electrode group is implanted into subcutaneous tissue, specifically including: The first working electrode is used to determine a first physiological parameter when the first working electrode is implanted into subcutaneous tissue; The second electrode group is used to determine a second physiological parameter when the second electrode group is implanted into subcutaneous tissue, specifically including: The second working electrode is used to determine a second physiological parameter when the second working electrode is implanted into subcutaneous tissue; The first electrode group and the second electrode group are further used to determine an electrocardiogram signal when the first electrode group and the second electrode group are implanted into subcutaneous tissue, specifically including: The first working electrode, the first pair of electrodes, and the second working electrode are further configured to determine an electrocardiogram (ECG) signal when the first working electrode, the first pair of electrodes, and the second working electrode are implanted into subcutaneous tissue.
17. The electronic device according to claim 15, wherein The first electronic device further includes a microcontroller unit (MCU); the first electrode group includes a first working electrode, a first reference electrode, and a first pair of electrodes; the second electrode group includes a second working electrode, a second reference electrode, and a second pair of electrodes. The first electrode group is configured to determine a first physiological parameter when the first electrode group is implanted into subcutaneous tissue, specifically including: The first working electrode is configured to generate a first current when the first working electrode is implanted into subcutaneous tissue. The first reference electrode is configured to control the voltage of the first working electrode. The first pair of electrodes is configured to form a loop with the first working electrode. The MCU is configured to determine the first physiological parameter based on the first current. The second electrode group is configured to determine a second physiological parameter when the second electrode group is implanted into subcutaneous tissue, specifically including: The second working electrode is configured to generate a second current when the second working electrode is implanted into subcutaneous tissue. The second reference electrode is configured to control the voltage of the second working electrode. The second pair of electrodes is configured to form a loop with the second working electrode. The MCU is configured to determine the second physiological parameter based on the second current.
18. The electronic device according to claim 17, wherein The first electrode group and the second electrode group are further configured to determine an ECG signal when the first electrode group and the second electrode group are implanted into subcutaneous tissue, specifically including: Any two electrodes in the first electrode group and any one electrode in the second electrode group are configured to determine an ECG signal when the first electrode group and the second electrode group are implanted into subcutaneous tissue. Or, Any one electrode in the first electrode group and any two electrodes in the second electrode group are configured to determine an ECG signal when the first electrode group and the second electrode group are implanted into subcutaneous tissue.
19. The electronic device according to claim 18, characterized in that, Any two electrodes in the first electrode group and any one electrode in the second electrode group are configured to determine an ECG signal when the first electrode group and the second electrode group are implanted into subcutaneous tissue, specifically including: When the first pair of electrodes is connected to a right leg drive circuit, the first pair of electrodes, the first working electrode, and the second reference electrode are configured to determine an ECG signal when the first electrode group and the second electrode group are implanted into subcutaneous tissue.
20. The electronic device according to claim 17, wherein The first electrode group further includes a first ECG electrode and a second ECG electrode, the second electrode group further includes a third ECG electrode, and the second ECG electrode is connected to a right leg drive circuit. The first electrode group and the second electrode group are further configured to determine an ECG signal when the first electrode group and the second electrode group are implanted into subcutaneous tissue, specifically including: The first ECG electrode, the second ECG electrode, and the third ECG electrode are configured to determine an ECG signal when the first electrode group and the second electrode group are implanted into subcutaneous tissue.
21. The electronic device according to any one of claims 15-20, characterized in that, The first electronic device further includes a first microneedle sensor and a second microneedle sensor. The first microneedle sensor includes the first electrode group, and the second microneedle sensor includes the second electrode group.
22. The electronic device according to any one of claims 15-20, characterized in that, The first electronic device further includes a first array sensor and a second array sensor. The first array sensor includes the first electrode group, and the second array sensor includes the second electrode group.
23. The electronic device according to any one of claims 15-22, characterized in that, The first electronic device further includes a communication module; The communication module is configured to send the first physiological parameter to a second electronic device; The communication module is further configured to send the electrocardiogram signal to the second electronic device.
24. A measurement circuit, characterized in that, It includes a first electrode group, a second electrode group, a first electrochemical circuit module, a second electrochemical circuit module, an electrocardiogram circuit module, and a microcontroller unit MCU; The first electrode group is connected to the first electrochemical circuit module and is also connected to the electrocardiogram circuit module; The second electrode group is connected to the second electrochemical circuit module and is also connected to the electrocardiogram circuit module; The MCU is connected to the first electrochemical circuit module, the second electrochemical circuit module, and the electrocardiogram circuit module; The first electrode group is used to generate a first current signal; The first electrode group is further used to conduct the first current signal to the first electrochemical circuit module; The first electrochemical circuit module is used to determine a second current signal based on the first current signal; The first electrochemical circuit module is further used to conduct the second current signal to the MCU; The MCU is used to determine a first physiological parameter based on the second current signal; The second electrode group is used to generate a third current signal; The second electrode group is further used to conduct the third current signal to the second electrochemical circuit module; The second electrochemical circuit module is used to determine a fourth current signal based on the third current signal; The second electrochemical circuit module is further used to conduct the fourth current signal to the MCU; The MCU is used to determine a second physiological parameter based on the fourth current signal; The first electrode group and the second electrode group are used to acquire a first electrocardiogram signal; The first electrode group and the second electrode group are further used to conduct the first electrocardiogram signal to the electrocardiogram circuit module; The electrocardiogram circuit module is used to determine a second electrocardiogram signal based on the first electrocardiogram signal; The electrocardiogram circuit module is further used to conduct the second electrocardiogram signal to the MCU.
25. The circuit according to claim 24, wherein The first electrode group includes a first working electrode, a first reference electrode, and a first counter electrode; the first electrochemical circuit module includes a first potentiostat circuit and a first transimpedance circuit; the first potentiostat circuit is used to control the voltages of the first working electrode and the first reference electrode; the first transimpedance circuit is used to amplify the first current signal; The connection between the first electrode group and the first electrochemical circuit module specifically includes: The first working electrode, the first reference electrode, and the first counter electrode are connected to the first potentiostat circuit; The first working electrode is connected to the first transimpedance circuit.
26. The circuit according to claim 25, wherein, The second electrode group includes a second working electrode, a second reference electrode, and a second counter electrode; the second electrochemical circuit module includes a second potentiostat circuit and a second transimpedance circuit; the second potentiostat circuit is used to control the voltage between the second working electrode and the second reference electrode; the second transimpedance circuit is used to amplify the third current signal; The second electrode group is connected to the second electrochemical circuit module, specifically including: The second working electrode, the second reference electrode, and the second counter electrode are connected to the second potentiostat circuit, The second working electrode is connected to the second transimpedance circuit.
27. The circuit according to claim 26, wherein The electrocardiogram circuit module includes a right leg drive circuit, an amplifier circuit, and a filter circuit, and the amplifier circuit is connected to the filter circuit; the right leg drive circuit is used to cancel the common mode signal, the amplifier circuit is used to amplify the first electrocardiogram signal, and the filter circuit is used for filtering; The first electrode group is connected to the electrocardiogram circuit module, specifically including: The first working electrode is connected to the amplifier circuit, and the first counter electrode is connected to the right leg drive circuit; The second electrode group is connected to the electrocardiogram circuit module, specifically including: The second reference electrode is connected to the amplifier circuit module; The first electrode group and the second electrode group are used to acquire a first electrocardiogram signal, specifically including: The first working electrode and the second reference electrode are used to acquire the first electrocardiogram signal; The first electrode group and the second electrode group are also used to conduct the first electrocardiogram signal to the electrocardiogram circuit module, specifically including: The first working electrode and the second reference electrode are used to conduct the first electrocardiogram signal to the amplifier circuit; The electrocardiogram circuit module is used to determine a second electrocardiogram signal based on the first electrocardiogram signal, specifically including: The amplifier circuit is used to amplify the first electrocardiogram signal and then conduct it to the filter circuit; The filter circuit is used to determine the second electrocardiogram signal based on the amplified first electrocardiogram signal; The electrocardiogram circuit module is also used to conduct the second electrocardiogram signal to the MCU, specifically including: The filter circuit is also used to conduct the second electrocardiogram signal to the MCU.
28. The circuit according to claim 26, wherein, The first electrode group further includes a first electrocardiogram electrode and a second electrocardiogram electrode, the second electrode group further includes a third electrocardiogram electrode, the electrocardiogram circuit module includes a right leg drive circuit, an amplifier circuit, and a filter circuit, and the amplifier circuit is connected to the filter circuit; the right leg drive circuit is used to cancel the common mode signal, the amplifier circuit is used to amplify the first electrocardiogram signal, and the filter circuit is used for filtering; The first electrode group is connected to the electrocardiogram circuit module, specifically including: The first electrocardiogram electrode is connected to the amplifier circuit, and the second electrocardiogram electrode is connected to the right leg drive circuit; The second electrode group is connected to the electrocardiogram circuit module, specifically including: The third electrocardiogram electrode is connected to the amplifier circuit module; The first electrode group and the second electrode group are used to conduct an electrocardiogram signal to the electrocardiogram circuit module, specifically including: The first electrocardiogram electrode and the third electrocardiogram electrode are used to conduct the electrocardiogram signal to the amplifier circuit; The electrocardiogram circuit module is used to determine a second electrocardiogram signal based on the first electrocardiogram signal, specifically including: The amplifier circuit is used to amplify the first electrocardiogram signal and then conduct it to the filter circuit; The filter circuit is used to determine the second electrocardiogram signal based on the amplified first electrocardiogram signal; The electrocardiogram circuit module is further used to conduct the second electrocardiogram signal to the MCU, specifically including: The filter circuit is also used to conduct the second electrocardiogram signal to the MCU.
29. A measurement circuit, characterized in that, It includes a first electrode group, a second electrode group, a first switch, a first electrochemical circuit module, an electrocardiogram circuit module, and a microcontroller unit MCU; the first switch includes a first group of input ports, a second group of input ports, and a first group of output ports, and the first switch is used to connect the first group of input ports or the second group of input ports; The first electrode group is connected to the first group of input ports, and the first electrode group is connected to the electrocardiogram circuit module; The second electrode group is connected to the second group of input ports, and the second electrode group is connected to the electrocardiogram circuit module; The first group of output ports is connected to the first electrochemical circuit module; The MCU is connected to the first electrochemical circuit module and the electrocardiogram circuit module; The first electrode group is used to generate a first current signal; The first electrode group is also used to conduct the first current signal to the first switch; The first switch is used to conduct the first current signal to the first electrochemical circuit module when the first group of input ports is connected; The first electrochemical circuit module is used to determine a second current signal based on the first current signal; The first electrochemical circuit module is also used to send the second current signal to the MCU; The MCU is used to determine a first physiological parameter based on the second current signal; The second electrode group is used to generate a third current signal; The second electrode group is also used to conduct the third current signal to the first switch; The first switch is used to conduct the third current signal to the first electrochemical circuit module when the second group of input ports is connected; The first electrochemical circuit module is also used to determine a fourth current signal based on the third current signal; The first electrochemical circuit module is also used to conduct the fourth current signal to the MCU; The MCU is used to determine a second physiological parameter based on the fourth current signal; The first electrode group and the second electrode group are used to acquire a first electrocardiogram signal; The first electrode group and the second electrode group are also used to conduct the first electrocardiogram signal to the electrocardiogram circuit module; The electrocardiogram circuit module is used to determine a second electrocardiogram signal based on the first electrocardiogram signal; The electrocardiogram circuit module is also used to conduct the second electrocardiogram signal to the MCU.
30. The circuit according to claim 29, characterized in that, The first electrode group includes a first working electrode, a first reference electrode, and a first counter electrode; the first set of input ports includes a first input port, a second input port, and a third input port; the second electrode group includes a second working electrode, a second reference electrode, and a second counter electrode; the second set of input ports includes a fourth input port, a fifth input port, and a sixth input port; The first working electrode is connected to the first input port, the first reference electrode is connected to the second input port, and the first counter electrode is connected to the third input port; The second working electrode is connected to the fourth input port, the second reference electrode is connected to the fifth input port, and the second counter electrode is connected to the sixth input port.
31. The circuit according to claim 30, wherein The first set of output ports includes a first output port, a second output port, and a third output port; The first switching switch is used to connect the first set of input ports, specifically including: The first output port is used to connect to the first input port, the second output port is used to connect to the second input port, and the third output port is used to connect to the third input port; The first switching switch is used to connect the second set of input ports, specifically including: The first output port is used to connect to the fourth input port, the second output port is used to connect to the fifth input port, and the third output port is used to connect to the sixth input port.
32. The circuit according to claim 31, wherein The first electrochemical circuit module includes a first potentiostat circuit and a first transimpedance circuit; the first potentiostat circuit is used to control the voltages of the first working electrode and the first reference electrode; the first transimpedance circuit is used to amplify the first current signal; The first set of output ports is connected to the first electrochemical circuit module, specifically including: The first output port, the second output port, and the third output port are connected to the first potentiostat circuit; The first output port is connected to the first transimpedance circuit.
33. A chip system, characterized in that, Applied to a first electronic device, the chip system includes: a processing circuit and an interface circuit, the interface circuit is used to receive code instructions and transmit them to the processing circuit, and the processing circuit is used to run the code instructions so that the chip system executes the method described in any one of the above claims 1-14.
34. A readable storage medium, comprising instructions, characterized in that, When the instruction runs on the first electronic device, it causes the first electronic device to execute the method described in any one of the above claims 1-14.