Cosmetic composition

Abstract

A cosmetic composition is disclosed comprising a substituted resorcinol complexed with a substituted cyclodextrin and a taurine-based polymeric thickener.

Description

Technical Field

[0001] This invention relates to a cosmetic composition comprising substituted resorcinol complexed with substituted cyclodextrin. It was unexpectedly discovered that the discoloration problem of the substituted resorcinol in this complex was significantly mitigated by incorporating a taurine-based polymeric thickener into the composition. Background Technology

[0002] Substituted resorcinols offer cosmetic benefits for skin and hair. Certain substituted resorcinols, particularly 4-hexylresorcinol, can be used in cosmetic compositions to provide skin brightening benefits.

[0003] However, when substituted resorcinols are incorporated into cosmetic compositions, the color of the composition tends to change due to a number of factors. Discoloration is a concern because consumers are sensitive to changes in the color appearance of the cosmetic compositions they use, especially when they might perceive a color change as an indication of chemical degradation. Discoloration of substituted resorcinols, particularly 4-substituted resorcinols used in skin-brightening compositions, is especially unpleasant for consumers seeking skin-brightening benefits. Numerous attempts have been made to minimize these drawbacks, but so far with limited success.

[0004] The inventors have determined that cyclodextrin compounds can form host-guest complexes with substituted resorcinols, and thus have the potential to reduce discoloration. However, the inventors have found that even this approach is not an ideal solution to the discoloration problem in some cosmetic compositions. Therefore, there is a need to further develop methods to prevent aesthetically unpleasant discoloration of substituted resorcinols in cosmetic compositions. It has been unexpectedly discovered that the color stability of compositions containing substituted resorcinols complexed with substituted cyclodextrins can be significantly improved by incorporating a taurine-based polymeric thickener into the composition. Summary of the Invention

[0005] In a first aspect, the present invention relates to a cosmetic composition comprising a substituted resorcinol complexed with a substituted cyclodextrin, and a taurine-based polymer.

[0006] In a second aspect, the present invention relates to a method for providing skin brightening to individual skin, comprising the step of topically applying the composition of the invention to at least a portion of the skin.

[0007] In a third aspect, the present invention relates to the use of the compositions of the present invention for skin brightening.

[0008] All other aspects of the invention will become more apparent upon consideration of the following detailed description and examples. Invention Details Unless expressly indicated in the examples or elsewhere, all figures indicating material amounts or reaction conditions, material physical properties and / or uses in this specification may optionally be understood to be modified by the word “about”.

[0010] Unless otherwise specified, all quantities are by weight of the composition.

[0011] It should be noted that when specifying any numerical range, any particular upper limit value can be associated with any particular lower limit value.

[0012] For the avoidance of doubt, the word "contains" is intended to mean "including," but not necessarily "composed of" or "consisting of." In other words, the steps or options listed do not have to be exhaustive.

[0013] The present invention disclosure found herein is intended to cover all embodiments found in the claims that are multi-dependent on each other, regardless of whether the claims may be in a non-multi-dependent or redundant manner.

[0014] When a feature is disclosed with respect to a particular aspect of the invention (e.g., the composition of the invention), that disclosure is also considered applicable to any other aspect of the invention (e.g., the method of the invention) with necessary modifications.

[0015] The substituted resorcinol used herein refers to resorcinol in which at least one hydrogen atom on the ring structure and / or hydroxyl group is substituted, preferably substituted with an alkyl group, a phenyl group, and / or a thiazolyl group. Preferably, the substituted resorcinol is a 4-substituted resorcinol, and more preferably, the substituted resorcinol is a 4-alkylresorcinol, and even more preferably, the substituted resorcinol is a 4-C1 to C1-C2 resorcinol. 12 Alkyl resorcinol, and even more preferably, the substituted resorcinol is 4-C1 to C8 alkyl resorcinol.

[0016] The substituted resorcinols that can be used in this invention preferably have the following formula (I): (I) Each R1 and R2 independently represents a hydrogen atom, C1-C 18 The alkyl group, R3, represents an alkyl or phenylalkyl group having 1 to 18 carbon atoms. In a preferred embodiment, both R1 and R2 represent hydrogen, and R3 represents an alkyl or phenylalkyl group having 1 to 18 carbon atoms. More preferably, both R1 and R2 represent hydrogen, and R3 represents an alkyl or phenylalkyl group having 2 to 12 carbon atoms. Even more preferably, both R1 and R2 represent hydrogen, and R3 is ethyl, propyl, butyl, pentyl, hexyl, heptyl, or octyl, and preferably R3 is ethyl, butyl, or hexyl.

[0017] Preferably, the substituted resorcinol includes thiamidol (isobutyramidothiazolylresorcinol), 2-methylresorcinol, 4-chlororesorcinol, 4-methylresorcinol, 4-ethylresorcinol, 4-propylresorcinol, 4-butylresorcinol, 4-pentylresorcinol, 4-hexylresorcinol, 4-heptylresorcinol, 4-octylresorcinol, 4-nonylresorcinol, 4-decylresorcinol, phenethylresorcinol, 4-acetylresorcinol, or mixtures thereof. More preferably, the substituted resorcinol comprises isobutamidothiazolyl resorcinol, 2-methylresorcinol, 4-chlororesorcinol, 4-methylresorcinol, 4-ethylresorcinol, 4-propylresorcinol, 4-butylresorcinol, 4-pentylresorcinol, 4-hexylresorcinol, 4-heptylresorcinol, 4-octylresorcinol, 4-nonylresorcinol, 4-decylresorcinol, phenethylresorcinol, 4-acetylresorcinol, or mixtures thereof. Even more preferably, the substituted resorcinol is selected from 4-ethylresorcinol, 4-butylresorcinol, 4-hexylresorcinol, phenethylresorcinol, or mixtures thereof. Still even more preferably, the substituted resorcinol is selected from 4-ethylresorcinol, 4-hexylresorcinol, or combinations thereof. Most preferably, the substituted resorcinol is 4-hexylresorcinol.

[0018] The amount of substituted resorcinol is preferably in the range of 0.0001 to 8% by weight, more preferably 0.001 to 5% by weight, even more preferably 0.005 to 3% by weight, even more preferably 0.02 to 1.8% by weight, even more preferably 0.05 to 1.2% by weight, and most preferably 0.1 to 0.6% by weight, based on the total amount of the composition. Preferably, the amount of 4-alkylresorcinol is in the range of 0.0001 to 8% by weight, more preferably 0.001 to 5% by weight, even more preferably 0.005 to 3% by weight, even more preferably 0.02 to 1.8% by weight, even more preferably 0.05 to 1.2% by weight, and most preferably 0.1 to 0.6% by weight, based on the total amount of the composition. Preferably, the total amount of 4-ethylresorcinol and 4-hexylresorcinol is in the range of 0.0001 to 8% by weight, more preferably 0.001 to 5% by weight, even more preferably 0.005 to 3% by weight, even more preferably 0.02 to 1.8% by weight, even more preferably 0.05 to 1.2% by weight, and most preferably 0.1 to 0.6% by weight, based on the total amount of the composition. Preferably, the amount of 4-hexylresorcinol is in the range of 0.0001 to 8% by weight, more preferably 0.001 to 5% by weight, even more preferably 0.005 to 3% by weight, even more preferably 0.02 to 1.8% by weight, even more preferably 0.05 to 1.2% by weight, and most preferably 0.1 to 0.6% by weight, based on the total amount of the composition.

[0019] As used herein, substituted cyclodextrin refers to a cyclodextrin in which one or more hydroxyl positions are substituted. Cyclodextrin typically contains six to twelve glucose units. Preferably, the cyclodextrin is selected from α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin, and mixtures thereof, more preferably β-cyclodextrin. Preferably, the substituted cyclodextrin is a cyclodextrin in which at least some of the hydroxyl groups have been converted to OR groups, wherein R generally represents an alkyl, hydroxyl, or nitrogen-containing functional group, preferably hydroxyalkyl, alkyl, carboxylalkyl, or aminoalkyl. More preferably, the substituted cyclodextrin is selected from hydroxyalkyl cyclodextrin, hydrocarbon-amino cyclodextrin, carbonate-substituted cyclodextrin, carboxylic acid-substituted cyclodextrin, and mixtures thereof. Even more preferably, the substituted cyclodextrin is a hydroxyalkyl cyclodextrin, preferably a hydroxy C1-C6 alkyl cyclodextrin. Even more preferably, the substituted cyclodextrin is a hydroxypropyl cyclodextrin.

[0020] Preferably, the substituted cyclodextrin has an average molar degree of substitution (MS) of 0.4 to 0.8, more preferably 0.5 to 0.71. The molar degree of substitution refers to the number of hydroxyl groups substituted in each pyranose unit. MS can be determined by proton nuclear magnetic resonance (NMR).

[0021] Without wishing to be bound by any theory or interpretation, it is believed that the substituted resorcinol is loaded into the "cavity" of the substituted cyclodextrin to form a host-guest complex. Preferably, the substituted resorcinol-substituted cyclodextrin complex comprises 60% to 99%, more preferably 80% to 97%, and even more preferably 88% to 95% of the substituted cyclodextrin, based on the weight of the complex. Preferably, the substituted resorcinol-substituted cyclodextrin complex comprises 1% to 40%, more preferably 3% to 20%, and even more preferably 5% to 12% of the substituted resorcinol, based on the weight of the complex. The cosmetic compositions of the present invention comprise the substituted resorcinol-substituted cyclodextrin complex and a taurine-based polymeric thickener. For clarity, the substituted resorcinol-substituted cyclodextrin complex is pre-formed.

[0022] Preferably, the amount of the substituted cyclodextrin is in the range of 0.001 to 25% by weight, more preferably 0.01 to 18% by weight, even more preferably 0.1 to 12% by weight, even more preferably 0.5 to 10% by weight, and even more preferably 2 to 6% by weight, based on the total amount of the composition. Preferably, the amount of the hydroxyalkyl-substituted cyclodextrin is in the range of 0.001 to 25% by weight, more preferably 0.01 to 18% by weight, even more preferably 0.1 to 12% by weight, even more preferably 0.5 to 10% by weight, and even more preferably 2 to 6% by weight, based on the total amount of the composition. Preferably, the amount of the hydroxypropyl cyclodextrin is in the range of 0.001 to 25% by weight, more preferably 0.01 to 18% by weight, even more preferably 0.1 to 12% by weight, even more preferably 0.5 to 10% by weight, and even more preferably 2 to 6% by weight, based on the total amount of the composition.

[0023] Preferably, the weight ratio of the substituted resorcinol to the substituted cyclodextrin is in the range of 1:100 to 1:1, more preferably 1:50 to 1:2, and even more preferably 1:20 to 1:5. Preferably, the weight ratio of 4-alkylresorcinol to hydroxyalkylcyclodextrin is in the range of 1:100 to 1:1, more preferably 1:50 to 1:2, and even more preferably 1:20 to 1:5. Preferably, the weight ratio of 4-hexylresorcinol to hydroxypropylcyclodextrin is in the range of 1:100 to 1:1, more preferably 1:50 to 1:2, and even more preferably 1:20 to 1:5.

[0024] Preferably, the taurine-based polymeric thickener is a polymer and / or copolymer (including crosslinked polymers) comprising 2-acrylamido-2-propanesulfonic acid (acryloyldimethyl taurine) or its salt as a constituent unit. More preferably, the taurine-based polymeric thickener is a copolymer comprising 2-acrylamido-2-propanesulfonic acid (acryloyldimethyl taurine) or its salt as a constituent unit. Preferably, the taurine-based polymeric thickener is selected from ammonium acryloyldimethyltaurate / betaine-25 methacrylate crosspolymer, ammonium acryloyldimethyltaurate / vinylpyrrolidone copolymer, ammonium acryloyldimethyltaurate / carboxyethyl acrylate crosspolymer, polyacrylate crosspolymer-11, dimethacrylamide / sodium acryloyldimethyltaurate crosspolymer, hydroxyethyl acrylate / sodium acryloyldimethyltaurate copolymer, sodium acrylate / acryloyldimethyltaurate / dimethacrylamide crosspolymer, sodium acryloyldimethyltaurate / methacrylamidoyl laurate copolymer, acrylamide / sodium acryloyldimethyltaurate / acrylic acid copolymer, ammonium acryloyldimethyltaurate / VP copolymer, and sodium polyacryloyldimethyltaurate. More preferably, the taurine-based polymeric thickener is selected from ammonium acryloyldimethyltaurate / betaine-25 methacrylate crosspolymer and ammonium acryloyldimethyltaurate / VP copolymer. Most preferably, the taurine-based polymeric thickener is selected from ammonium acryloyl dimethyl taurate / betaine polyether-25 methacrylate crosspolymer.

[0025] Preferably, the amount of the taurine-based polymeric thickener is in the range of 0.01 to 8% by weight, more preferably 0.05 to 4% by weight, even more preferably 0.1 to 2% by weight, and even more preferably 0.2 to 0.6% by weight, based on the total amount of the composition.

[0026] Preferably, the weight ratio of the taurine-based polymeric thickener to the substituted cyclodextrin is in the range of 1:100 to 1:1, more preferably 1:50 to 1:2, and even more preferably 1:20 to 1:5. Preferably, the weight ratio of the taurine-based polymeric thickener to the hydroxyalkyl cyclodextrin is in the range of 1:100 to 1:1, more preferably 1:50 to 1:2, and even more preferably 1:20 to 1:5. Preferably, the weight ratio of the taurine-based polymeric thickener to the hydroxypropyl cyclodextrin is in the range of 1:100 to 1:1, more preferably 1:50 to 1:2, and even more preferably 1:20 to 1:5.

[0027] Preferably, the weight ratio of the taurine-based polymeric thickener to the substituted resorcinol is in the range of 1:50 to 50:1, more preferably 1:20 to 20:1, even more preferably 1:8 to 8:1, and even more preferably 3:1 to 1:3. Preferably, the weight ratio of the taurine-based polymeric thickener to 4-alkylresorcinol is in the range of 1:50 to 50:1, more preferably 1:20 to 20:1, even more preferably 1:8 to 8:1, and even more preferably 3:1 to 1:3.

[0028] Preferably, the composition may additionally comprise skincare active ingredients that can be used to obtain skincare benefits (e.g., for improving the physical and / or aesthetic properties of the skin). Examples of additional skincare active ingredients suitable for use in the present invention include vitamins, minerals and / or antioxidants, emollients, moisturizers, skin brighteners, sunscreens, anti-irritants, exfoliants and / or any combination or mixture thereof. In one aspect, the cosmetic composition is substantially sulfate-free, preferably having less than 5%, or less than 3%, or less than 1%, or less than 0.5%, or less than 0.1% sulfate by weight of the composition.

[0029] In addition, the composition may include additional functional ingredients selected from dyes, preservatives, pH adjusters, and fragrances. In one aspect, the composition is substantially free of parabens and has less than 5%, or less than 3%, or less than 1%, or less than 0.5%, or less than 0.1%, or 0% parabens.

[0030] Preferably, the composition comprises a vitamin B3 compound (including derivatives of vitamin B3). The vitamin B3 compound comprises nicotinic acid, niacin, nicotinamide, or mixtures thereof. The most preferred vitamin B3 compound is nicotinamide. The amount of the vitamin B3 compound can be from 0.1% to 10%, preferably from 0.5% to 5%, based on the weight of the composition.

[0031] The composition preferably further comprises one or more organic sunscreens. A wide range of organic sunscreens are suitable for use in combination with the essential ingredients of this invention. Suitable UV-A / UV-B sunscreens include 2-hydroxy-4-methoxybenzophenone, octyl dimethyl para-aminobenzoic acid, trioleate digallate, 2,2-dihydroxy-4-methoxybenzophenone, ethyl 4-(bis(hydroxypropyl))aminobenzoate, 2-cyano-3,3-diphenylacrylate-2-ethylhexyl ester, 2-ethylhexyl salicylate, glyceryl para-aminobenzoate, and 3,3,5-trimethylaminobenzoate. Methylcyclohexyl ester, methyl anthranilate, p-dimethylaminobenzoic acid or aminobenzoate, 2-ethylhexyl p-dimethylaminobenzoic acid, 2-phenylbenzimidazole-5-sulfonic acid, benzoxazolium 2-(p-dimethylaminophenyl)-5-sulfonic acid, 2-ethylhexyl p-methoxycinnamate, butylmethoxydibenzoylmethane, 2-hydroxy-4-methoxybenzophenone, octyldimethylp-aminobenzoic acid, and mixtures thereof. The most suitable organic sunscreen agents are 2-ethylhexyl p-methoxycinnamate, butylmethoxydibenzoylmethane, or mixtures thereof. A safe and effective amount of the organic sunscreen agent can be used in the compositions of the subject matter of this invention. The composition preferably contains 0.1% to 10%, more preferably 0.1% to 5% of the organic sunscreen agent, by weight of the composition.

[0032] Preferably, the composition comprises a polyol. The polyol may be selected from glycerol, propylene glycol, dipropylene glycol, polypropylene glycol, polyethylene glycol, sorbitol, hydroxypropyl sorbitol, hexanediol, 1,3-butanediol, isopentyl glycol, ethoxylated glycerol, propoxylated glycerol, or mixtures thereof. The most preferred polyol is glycerol, also known as glycerol. The amount of the polyol may range from 0.1% to 20%, preferably from 0.5% to 15%, more preferably from 2% to 10% by weight of the composition.

[0033] Water-insoluble skin-beneficial agents can also be formulated into compositions as conditioning and moisturizing agents. Examples include silicone oils; and plant triglycerides such as sunflower seed oil and cottonseed oil.

[0034] Preservatives may be incorporated into the compositions of the present invention as needed to prevent the growth of potentially harmful microorganisms. Suitable conventional preservatives for use in the compositions of the present invention are alkyl esters of hydrobenzoic acid. Other preservatives that have been used more recently include hydantoin derivatives, propionates, and various quaternary ammonium compounds. Particularly preferred preservatives are phenoxyethanol, methylparaben, propylparaben, imidazolidinyl urea, sodium dehydroacetate, and benzyl alcohol. The preservative should be selected taking into account the intended use of the composition and possible incompatibilities between the preservative and other components. The preservative is preferably used in an amount ranging from 0.01% to 2% by weight of the composition.

[0035] Various other optional materials may be formulated into the composition. These may include: antimicrobial agents such as 2,6-dimethyl-4-hydroxychlorobenzene and 3,4,4'-triclocarban; exfoliating and dermal exfoliating particles such as polyethylene and silica or alumina; cooling agents such as menthol; skin soothing agents such as aloe vera; and colorants.

[0036] Furthermore, the compositions of the present invention may further comprise 0.5 to 10% by weight of a chelating agent, such as tetrasodium ethylenediaminetetraacetate (EDTA), EHDP, or a mixture thereof; opacifiers and pearlescent agents such as ethylene glycol distearate, titanium dioxide, or Lytron 621 (styrene / acrylate copolymer); all of which can be used to enhance the appearance or properties of the product.

[0037] The composition may contain 10% to 96% water, more preferably 25% to 92%, even more preferably 42% to 88%, and most preferably 55% to 82% by weight of the composition.

[0038] The viscosity of the composition is preferably 1 to 500 Pa·s, more preferably 5 to 150 Pa·s, even more preferably 10 to 60 Pa·s, and most preferably 20 to 40 Pa·s. The viscosity used herein was determined using a rheometer (Anton Paar Rheometer MCR501, Austria) with a sandblasted parallel plate (PP50) at a plate-to-plate gap of 0.5 mm and a shear rate of 10 s⁻¹. -1 Measured at 25℃.

[0039] Preferably, the composition is an emulsion, more preferably an oil-in-water emulsion. Preferably, the cosmetic composition is a skin care composition. A skin care composition refers to a composition suitable for topical application to human skin, including leave-on and rinse-off products, but preferably leave-on compositions. The term "leave-on" as used herein refers to a composition that is applied to or rubbed onto the skin and remains thereon. The term "rinse-off" as used herein refers to a skin cleanser that is applied to or rubbed onto the skin and is rinsed off substantially immediately after application. The term "skin" as used herein includes the skin of the face, neck, chest, abdomen, back, arms, armpits, hands, and legs. Preferably, "skin" means the skin including the face and armpits, more preferably the facial skin excluding the lips and eyelids. The composition is particularly preferably a moisturizer rather than a makeup product.

[0040] Preferably, the composition is a topical composition. Preferably, the composition may be in the form of a cream, emulsion, ointment, solution, suspension, lotion, paste, gel, powder, foundation, emulsion foundation, wax foundation, or spray. More preferably, the composition may be formulated as a cream, emulsion, ointment, lotion, gel, or spray.

[0041] Preferably, the use is non-therapeutic. Preferably, the method is non-therapeutic. The term non-therapeutic generally means used for cosmetic purposes rather than for curative or therapeutic purposes.

[0042] The following embodiments are provided to facilitate understanding of the invention. These embodiments are not intended to limit the scope of the claims. Detailed Implementation

[0043] Example Example 1 This example demonstrates the effectiveness of combining a taurine-based polymeric thickener with a substituted resorcinol-substituted cyclodextrin complex.

[0044] (a) Preparation of substituted resorcinol-substituted cyclodextrin complexes Mix 0.4 g of 4-hexylresorcinol and 4 g of hydroxypropyl cyclodextrin (Roquette® CD110, purchased from Roquette), and then stir the mixture at room temperature for 15 minutes.

[0045] (b) Preparation of skin care compositions Table 1

[0046] a: Aristoflex® AVC, purchased from Clariant Ltd.

[0047] b: Aristoflex® HMB, purchased from Clariant Ltd.

[0048] c: Aristoflex® Silk Polymer, purchased from Clariant Ltd.

[0049] d: Pemulen™ EZ-4U polymer, purchased from Lubrizol Corporation.

[0050] e: Natrosol™ 250HHR, purchased from Ashland.

[0051] f: Keltrol® CG-T, purchased from CP Kelco.

[0052] g: Structure XL, purchased from Nouryon.

[0053] h: Prepared according to (a) of this embodiment.

[0054] A range of skin care compositions are formulated according to Table 1 by following standard procedures.

[0055] (c) Color stability test The performance of the samples was evaluated using the following procedure: All samples were placed in the same quantity into identical transparent vials. These vials containing the samples were then placed in an oven at 55°C for two weeks. Afterward, the vials containing the samples were removed, observed, and the results recorded in Table 2.

[0056] Table 2

[0057] *0: No discoloration; 1: Very slight discoloration; 2: Slight discoloration; 3: Acceptable discoloration; 4: Obvious discoloration; 5: Severe discoloration.

[0058] Unexpectedly, it was found that the discoloration problem was significantly reduced only when the taurine-based polymeric thickener was combined with substituted resorcinol-substituted cyclodextrin complexes (samples 1, 2, and 3). In contrast, other types of thickeners did not alleviate the discoloration problem.

[0059] Example 2 This embodiment demonstrates the effect of a composition comprising a substituted resorcinol-substituted cyclodextrin complex relative to a composition comprising separate substituted resorcinol and substituted cyclodextrin.

[0060] Sample 2 in Table 1 was prepared using the same procedure as described in Example 1, namely, preparing a hydroxypropyl cyclodextrin-4-hexylresorcinol complex, and then combining this complex with the other components of the composition. Sample E, having the same composition as Sample 2, was prepared by separately combining 4-hexylresorcinol and hydroxypropyl cyclodextrin.

[0061] Color stability testing was conducted. Both samples were placed in the same amount in identical transparent bottles and then placed in a cabinet under continuous illumination with a 2W light source at ambient temperature. After two weeks, the two transparent bottles containing the samples were removed and observed. Unexpectedly, sample 2 showed significantly less discoloration than sample E, indicating that the discoloration problem could only be significantly mitigated when the composition contained a substituted resorcinol-substituted cyclodextrin complex (rather than separately containing substituted resorcinol and substituted cyclodextrin).

Claims

1. A cosmetic composition comprising: (a) substituted resorcinol complexed with substituted cyclodextrin; and (b) taurine-based polymeric thickeners.

2. The composition according to claim 1, wherein the substituted resorcinol is a 4- substituted resorcinol, preferably 4-Ci to C 12 alkyl resorcinol.

3. The composition according to claim 1 or 2, wherein the substituted resorcinol comprises tiamine, 2-methylresorcinol, 4-chlororesorcinol, 4-methylresorcinol, 4-ethylresorcinol, 4-propylresorcinol, 4-butylresorcinol, 4-pentylresorcinol, 4-hexylresorcinol, 4-heptylresorcinol, 4-octylresorcinol, 4-nonylresorcinol, 4-decylresorcinol, phenylethylresorcinol, 4-acetylresorcinol, or mixtures thereof, preferably the substituted resorcinol selected from 4-ethylresorcinol, 4-hexylresorcinol, or combinations thereof.

4. The composition according to any one of the preceding claims, wherein the amount of the substituted resorcinol is in the range of 0.0001 to 8% by weight, preferably 0.02 to 1.8% by weight, based on the total amount of the composition.

5. The composition according to any one of the preceding claims, wherein the substituted cyclodextrin is selected from hydroxyalkyl cyclodextrin, hydrocarbon-amino cyclodextrin, carbonate-substituted cyclodextrin, carboxylic acid-substituted cyclodextrin, and mixtures thereof, preferably the substituted cyclodextrin is hydroxyalkyl cyclodextrin, and more preferably the substituted cyclodextrin is hydroxypropyl cyclodextrin.

6. The composition according to any one of the preceding claims, wherein the substituted cyclodextrin has an average molar degree of substitution of 0.4 to 0.

8.

7. The composition according to any one of the preceding claims, wherein the amount of the substituted cyclodextrin is in the range of 0.001 to 25% by weight, preferably 0.1 to 12% by weight, based on the total amount of the composition.

8. The composition according to any one of the preceding claims, wherein the weight ratio between the substituted resorcinol and the substituted cyclodextrin is in the range of 1:100 to 1:1, preferably 1:20 to 1:

5.

9. The composition according to any one of the preceding claims, wherein the taurine-based polymeric thickener is a polymer and / or copolymer comprising 2-acrylamido-2-propanesulfonic acid or a salt thereof as a constituent unit.

10. The composition according to any one of the preceding claims, wherein the taurine-based polymeric thickener is selected from ammonium acryloyl dimethyl taurate / benzyl alcohol polyether-25 methacrylate crosspolymer, ammonium acryloyl dimethyl taurate / vinylpyrrolidone copolymer, ammonium acryloyl dimethyl taurate / carboxyethyl acrylate crosspolymer, polyacrylate crosspolymer-11, dimethacrylamide / sodium acryloyl dimethyl taurate crosspolymer, hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, sodium acrylate / acryloyl dimethyl taurate / dimethacrylamide crosspolymer, sodium acryloyl dimethyl taurate / methacrylamidoyl lauric acid copolymer, acrylamide / sodium acryloyl dimethyl taurate / acrylic acid copolymer, ammonium acryloyl dimethyl taurate / VP copolymer, and sodium polyacryloyl dimethyl taurate, preferably the taurine-based polymeric thickener is selected from ammonium acryloyl dimethyl taurate / benzyl alcohol polyether-25 methacrylate crosspolymer and ammonium acryloyl dimethyl taurate / VP copolymer.

11. The composition according to any one of the preceding claims, wherein the amount of the taurine-based polymeric thickener is in the range of 0.01 to 8% by weight, preferably 0.1 to 2% by weight, based on the total amount of the composition.

12. The composition according to any one of the preceding claims, wherein the weight ratio between the taurine-based polymeric thickener and the substituted cyclodextrin is in the range of 1:100 to 1:1, preferably 1:20 to 1:

5.

13. The composition according to any one of the preceding claims, wherein the weight ratio between the taurine-based polymeric thickener and the substituted resorcinol is in the range of 1:50 to 50:1, preferably 1:8 to 8:

1.

14. A method for providing skin brightening to individual skin, comprising the step of topically applying the composition of any one of the preceding claims to at least a portion of the skin.

15. Use of a taurine-based polymeric thickener in a composition according to any one of claims 1 to 13 for skin brightening.

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