Multi-effect skin care chinese herbal extract composition and its use in the preparation of a cosmetic
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- YUNBIN (GUANGZHOU) HEALTH TECHNOLOGY CO LTD
- Filing Date
- 2026-07-03
- Publication Date
- 2026-08-04
AI Technical Summary
[0005]但是现有技术的种种方案均缺乏莼菜(Braseniaschreberi)、黄芩(Scutellariabaicalensis)、人参(Panaxginseng)、苍术(Atractylodesmacrocephala)、甘草(Glycyrrhizauralensis)等二种或多种的复合提取以及在护肤品中的创新应用
1)本发明通过对莼菜、黄芩、人参、苍术、甘草进行针对性创新提取,并进行科学复配,得到一种适用于化妆品的多效护肤中草药提取物组合物。莼菜提取物保留多糖与胶质,显著提升保湿成膜性能;黄芩、甘草、人参提取物富含黄酮、皂苷、多糖等成分,具备抗氧化、舒缓及修护作用;苍术提取物可改善控油和肤感;通过针对性提取工艺,减少杂质,提高化妆品适配性;各提取物复配后形成保湿、舒缓、抗氧化、控油、修护的协同护肤效应;
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Abstract
Description
Technical Field
[0001] This invention relates to the application of herbal extracts in cosmetics, and more particularly to a multi-effect skincare herbal extract composition and its application in the preparation of cosmetics. Background Technology
[0002] Currently, most herbal ingredients in cosmetics are extracted individually or simply mixed, making it difficult to leverage the synergistic effects between herbs. Furthermore, traditional extraction methods suffer from low extraction rates, significant loss of active ingredients, and instability of components. There is an urgent need to develop innovative extraction processes to improve the activity of individual components and overall efficacy.
[0003] Chinese Patent Application No. 202011260822.5 discloses a traditional Chinese medicine extract composition, its preparation method, and its application. The method for preparing the traditional Chinese medicine extract composition includes the following steps: weighing Angelica sinensis and Paeonia suffruticosa root bark separately, mixing them according to a preset weight ratio, dissolving them in ethanol to prepare a raw material solution, wherein the material-to-liquid ratio of the raw material solution is 1:10 to 1:30; subjecting the raw material solution to ultrasonic extraction to prepare an extract, wherein the ultrasonic power of the ultrasonic extraction is 100W to 500W, the extraction temperature is 40℃ to 70℃, the extraction is performed 1 to 2 times, and the extraction time is 40min to 90min each time; purifying the extract. This traditional Chinese medicine extract composition has beneficial effects such as skin brightening, antioxidant properties, and antibacterial activity. It also provides applications of this traditional Chinese medicine extract composition in the preparation of skincare products or as a preservative.
[0004] Chinese Patent Application No. 201810679122.6 discloses an anti-aging traditional Chinese medicine extract composition, its preparation, and its application in cosmetics. This anti-aging traditional Chinese medicine extract composition comprises the following components in parts by weight: 30-40 parts gentian, 20-30 parts angelica, 15-23 parts centella asiatica, 10-15 parts red sesame seeds, and 8-12 parts Sichuan pepper. Incorporating this anti-aging traditional Chinese medicine extract composition into cosmetic formulations can simultaneously combat aging, brighten the skin, and nourish it. By enhancing skin immunity and promoting cell metabolism, it delays skin aging, resulting in significant nourishing and anti-aging effects when added to cosmetics.
[0005] However, existing technologies lack the ability to extract two or more of the following herbs in combination, such as water shield (Brasenia schreberi), scutellaria baicalensis, ginseng (Panax ginseng), atractylodes macrocephala, and licorice (Glycyrrhiza uralensis), and to innovate their application in skincare products. This is a technical challenge that urgently needs to be addressed by those skilled in the art. Summary of the Invention
[0006] To address the problems existing in the prior art, the purpose of this invention is to provide a combination of herbal extracts that combines gentleness, stability, and synergistic effects of multiple functions. This multi-effect skin care herbal extract composition and its preparation method involve targeted and innovative extraction of water shield, scutellaria baicalensis, ginseng, atractylodes lancea, and licorice to obtain highly active, low-impurity plant extracts suitable for cosmetic applications. Through scientific compounding, it achieves synergistic effects such as moisturizing, soothing, anti-oxidation, repairing, oil control, and improving skin texture.
[0007] Another objective of this invention is to provide an application of the above-mentioned multi-functional synergistic herbal extract composition in the preparation of cosmetics, which simultaneously addresses multiple skincare needs such as moisturizing, soothing, anti-oxidation, oil control, and skin barrier repair.
[0008] To achieve the above objectives, the present invention employs the following technical solutions.
[0009] A multi-effect skincare herbal extract composition comprises the following components in parts by weight: Water shield extract: 10-35 parts; Scutellaria baicalensis extract: 10-30 parts; Ginseng extract: 10-25 parts; Atractylodes lancea extract: 5-20 parts; Licorice extract: 10-30 parts.
[0010] Furthermore, the multi-effect skincare herbal extract composition is composed of the following components in parts by weight: Water shield extract: 18-28 parts; Scutellaria baicalensis extract: 15-25 parts; Ginseng extract: 15-22 parts; Atractylodes lancea extract: 8-15 parts; Licorice extract: 15-25 parts.
[0011] Furthermore, the multi-effect skincare herbal extract composition is composed of the following components in parts by weight: 25 parts of water shield extract; 20 parts of Scutellaria baicalensis extract; 18 portions of ginseng extract; 12 parts of Atractylodes lancea extract; 25 parts of licorice extract.
[0012] Furthermore, the multi-effect skin care herbal extract composition is obtained by premixing each extract at 40~50℃ for 20 min, and then dispersing it at low speed of 300~500 rpm for 30 min.
[0013] Furthermore, the extraction process steps of the water shield extract are as follows: Step 1: Raw material pretreatment Remove impurities from fresh or dried water shield raw materials, wash them, dry them at a low temperature of 40~50℃ until the moisture content is ≤10%, and then crush them through a 40~60 mesh sieve; Step 2: Low-temperature complex enzymatic hydrolysis Add purified water at a material-to-liquid ratio of 1:(12~18), adjust the pH to 4.8~5.5, add a compound enzyme (cellulase: pectinase = 1:1, the total enzyme content is 0.8%~1.5% of the raw material mass), and enzymatically hydrolyze at 45~52℃ for 1.5~3.0 h to break the cell wall and release polysaccharides and gums. Step 3: Segmented hot water extraction After enzymatic hydrolysis, the temperature is raised to 75~85℃ for two-stage hot water extraction: first extraction: material-to-liquid ratio 1:(10~12), extraction time 1.0~1.5 h; second extraction: material-to-liquid ratio 1:(8~10), extraction time 0.8~1.2 h, and the extracts are combined. Step 4: Membrane separation and purification Ultrafiltration membrane (molecular weight cutoff 10~30 kDa) is used for separation to remove small molecule impurities and some pigments, while retaining large molecule polysaccharides and colloidal active components; Step 5: Vacuum low-temperature concentration and spray drying The filtrate was concentrated under vacuum at a temperature below 55°C to a solid content of 15% to 25%, and then spray-dried at an inlet air temperature of 140 to 165°C and an outlet air temperature of 75 to 90°C to obtain water shield extract powder.
[0014] Furthermore, the extraction process steps of the Scutellaria baicalensis extract are as follows: Step 1: Raw material pretreatment After washing, the Scutellaria baicalensis root is dried at a temperature below 60°C, then pulverized and passed through a 40-mesh sieve. Step 2: Eutectic solvent-assisted alcohol extraction Prepare a green eutectic solvent (choline chloride-lactic acid system, molar ratio 1:2), add 5%~15% by volume to 50%~70% ethanol, extract at a material-liquid ratio of 1:(8~12), and perform ultrasonic-assisted extraction at 60~75℃ for 30~60 min. Step 3: Reflux and secondary extraction The residue was then refluxed with 50%–70% ethanol 1–2 times, each time for 1.0–1.5 h, and the extracts were combined. Step 4: Reduce pressure to recover ethanol Ethanol was recovered to a content of less than 10% under conditions of 45~55℃ and -0.08~-0.095 MPa. Step 5: Macroporous resin enrichment Adsorption was performed using AB-8 or D101 macroporous resin, with the sample loading flow rate controlled at 1.0~2.0 BV / h. After washing with water to remove impurities, the sample was eluted with a gradient of 50%~80% ethanol to collect the flavonoid-rich fraction of Scutellaria baicalensis. Step 6: Concentration and Drying The eluent was concentrated under reduced pressure and then dried under low temperature vacuum or spray-dried to obtain Scutellaria baicalensis extract powder.
[0015] Furthermore, the extraction process steps of the ginseng extract are as follows: Step 1: Raw material pretreatment After ginseng slices are dried at low temperature, they are pulverized and passed through a 20-40 mesh sieve. Step 2: Gradient alcohol extraction Use 30%~60% ethanol as the extraction solvent, with a solid-liquid ratio of 1:(10~15), and reflux extraction at 50~65℃ for 1.5~2.5 h, for 2 extractions; Step 3: Ultrasonic Enhanced Extraction The second extraction can be performed with ultrasound assistance, using an ultrasound power of 200-500 W, a temperature of 45-60℃, and a time of 20-40 min, to promote saponin release. Step 4: Membrane fractionation purification After combining the extracts, the extracts are fractionated by nanofiltration or ultrafiltration to preferentially retain saponins and polysaccharide complex active components with relatively high molecular weight, while removing some pigments and small molecule impurities. Step 5: Low-temperature concentration and freeze-drying After concentration at below 50°C, the extract was pre-frozen at -40°C and then freeze-dried under vacuum to obtain a highly active ginseng extract powder.
[0016] Furthermore, the extraction process steps of the Atractylodes lancea extract include: Step 1: Raw material pretreatment After cleaning, the rhizome of Atractylodes lancea is dried at low temperature and then pulverized and passed through a 20-40 mesh sieve. Step 2: Supercritical CO2 extraction of volatile components Supercritical CO2 extraction was employed at a pressure of 20–30 MPa, a temperature of 35–45 °C, a CO2 flow rate of 15–30 kg / h, and an extraction time of 1.5–3 h. 5%–10% ethanol was used as an entrainer to improve the extraction efficiency of polar components. Step 3: Secondary extraction with ethanol The residue was then refluxed with 60%~80% ethanol at a material-to-liquid ratio of 1:(8~12) 1~2 times, each time for 1~1.5 h, to obtain Atractylodes polyphenols and auxiliary active ingredients; Step 4: Low-temperature solvent removal and standardization After combining the extracts, the concentration was carried out under reduced pressure to control the final volatile oil content and total solids content. If necessary, microencapsulation or cyclodextrin inclusion treatment was performed to improve stability and odor compatibility.
[0017] Furthermore, the extraction process of the licorice extract includes: Step 1: Raw material pretreatment Licorice root and stem are washed, dried, and pulverized through a 40-mesh sieve; Step 2: Acid-base regulation - combined water and alcohol extraction Add the raw material to 40%~60% ethanol at a material-to-liquid ratio of 1:(10~15), add 0.05%~0.20% citric acid or lactic acid to adjust the pH of the system to 5.0~6.0, and reflux extract at 55~70℃ for 1~2 h; Step 3: Ultrasonic-assisted extraction Ultrasound was applied during the extraction process at a power of 150-400 W for 20-45 min to enhance the dissolution of glycyrrhizic acid and flavonoids. Step 4: Macroporous resin enrichment and decolorization Adsorption was performed using AB-8, HPD-100 or XAD series macroporous resins. Sugar impurities were first removed by washing with water, and then eluted with 40%~75% ethanol to obtain a component rich in glycyrrhizic acid and flavonoids. Step 5: Concentration and Drying The licorice extract was obtained by concentration under reduced pressure and vacuum drying.
[0018] Furthermore, this invention also discloses the application of a multi-effect skin care herbal extract composition in the preparation of cosmetics, wherein the herbal extract composition accounts for 1.5-12% by mass in the cosmetics, and the remainder is conventional cosmetic excipient matrix.
[0019] Furthermore, the herbal extract composition constitutes 2-6% by mass in the cosmetic; the dosage forms of the cosmetic include, but are not limited to, moisturizing and repairing lotions, multi-effect repairing serums, repairing creams, soothing and repairing masks, oil-controlling gels, and anti-allergic soothing sprays.
[0020] By employing the above technical solution, the present invention has the following beneficial technical effects: 1) This invention utilizes targeted and innovative extraction of water shield, scutellaria baicalensis, ginseng, atractylodes lancea, and licorice, followed by scientific compounding, to obtain a multi-effect skincare herbal extract composition suitable for cosmetics. Water shield extract retains polysaccharides and mucilage, significantly enhancing its moisturizing and film-forming properties; scutellaria baicalensis, licorice, and ginseng extracts are rich in flavonoids, saponins, and polysaccharides, possessing antioxidant, soothing, and repairing effects; atractylodes lancea extract improves oil control and skin feel; targeted extraction processes reduce impurities and enhance cosmetic compatibility; the compounded extracts create a synergistic skincare effect of moisturizing, soothing, antioxidant, oil-controlling, and repairing. 2) This invention employs processes such as low-temperature enzymatic hydrolysis, deep eutectic solvent-assisted extraction, supercritical extraction, and membrane separation to improve the yield of active ingredients; reduce low-molecular-weight impurities, pigments, and irritating components, thereby improving the applicability of cosmetics; the five extracts, when combined, can form synergistic effects in moisturizing, repairing, soothing, anti-oxidation, and oil control; it is suitable for various cosmetic formulations such as aqueous solutions, emulsions, creams, masks, and gels; the process is green and environmentally friendly, and suitable for industrial-scale production.
[0021] 2) The herbal extract composition of the present invention exhibits significant synergistic effects in moisturizing, anti-oxidation, soothing and anti-irritation, oil control and skin cleansing, and repair. It can be widely used in various skin care product formulations and is suitable for various skin care product systems; it has good industrialization prospects. Detailed Implementation
[0022] To better illustrate the present invention, the following detailed description is provided in conjunction with specific embodiments. However, these specific embodiments are merely for illustrative purposes and are not intended to limit the scope of the invention.
[0023] With the increasing demand from consumers for gentle, safe, and natural cosmetics, skincare active ingredients derived from traditional Chinese medicine have gained widespread attention due to their high biocompatibility, low irritation, and multi-target effects. Existing single-plant extracts often suffer from narrow scope of action, limited efficacy, insufficient stability, or insignificant synergistic effects when combined with other ingredients. Especially in multi-functional skincare scenarios, a single ingredient struggles to simultaneously address multiple aspects such as moisturizing, soothing, anti-oxidation, oil control, and skin barrier repair.
[0024] This invention relates to the field of natural plant active substance extraction and cosmetic technology, specifically to a multi-effect skin care herbal extract composition composed of water shield extract, scutellaria baicalensis extract, ginseng extract, atractylodes lancea extract, and licorice extract, and its application in cosmetics such as moisturizing, soothing, anti-oxidation, repairing, oil control, and improving skin texture.
[0025] Water shield (Brasenia schreberi) is rich in polysaccharides and pectin, possessing excellent film-forming and moisturizing potential; Scutellaria baicalensis contains baicalin and baicalein, exhibiting antioxidant and soothing effects; Ginseng contains ginsenosides, possessing repair-promoting and anti-aging value; Atractylodes lancea contains volatile components and sesquiterpenes, offering both refreshing oil control and skin conditioning effects; Licorice contains glycyrrhizic acid and glycyrrhizin flavonoids, providing soothing, anti-inflammatory, and skin-conditioning effects. Through rational extraction, targeted enrichment, and scientific compounding, multi-component and multi-pathway synergy can be achieved, resulting in a stronger multi-effect skincare regimen.
[0026] This invention aims to provide a multi-effect skin care herbal extract composition and its preparation method. By selectively and innovatively extracting water shield, scutellaria baicalensis, ginseng, atractylodes lancea, and licorice, a highly active, low-impurity plant extract suitable for cosmetic applications is obtained. Through scientific compounding, the synergistic effects of moisturizing, soothing, anti-oxidation, repairing, oil control, and improving skin texture are achieved.
[0027] The multi-effect skincare herbal extract composition of this invention consists of five extracts: water shield extract; scutellaria baicalensis extract; ginseng extract; atractylodes lancea extract; and licorice extract. Each extract is prepared using a specific innovative extraction process, and then blended in a certain proportion to obtain the multi-effect skincare herbal extract composition.
[0028] 1. Innovative extraction process of water shield extract Water shield is rich in polysaccharides, colloids, amino acids and a small amount of phenolic substances. It is suitable for low-temperature enzymatic hydrolysis-segmented water extraction-membrane separation-low-temperature concentration process to maximize the preservation of its natural polysaccharides and moisturizing film-forming activities.
[0029] Process steps: Step 1: Raw material pretreatment Remove impurities from fresh or dried water shield raw materials, wash them, and dry them at a low temperature of 40~50℃ until the moisture content is ≤10%. Then, crush them and pass them through a 40~60 mesh sieve.
[0030] Step 2: Low-temperature complex enzymatic hydrolysis Add purified water at a material-to-liquid ratio of 1:(12~18), adjust the pH to 4.8~5.5, add a compound enzyme (cellulase: pectinase = 1:1, the total enzyme content is 0.8%~1.5% of the raw material mass), and enzymatically hydrolyze at 45~52℃ for 1.5~3.0 h to break the cell wall and release polysaccharides and gums.
[0031] Step 3: Segmented hot water extraction After enzymatic hydrolysis, the temperature is raised to 75-85℃ for two-stage hot water extraction: First extraction: material-to-liquid ratio 1:(10~12), extraction for 1.0~1.5 h; Second extraction: material-to-liquid ratio 1:(8~10), extraction for 0.8~1.2 h.
[0032] Combine the extracts.
[0033] Step 4: Membrane separation and purification Ultrafiltration membranes (with a molecular weight cutoff of 10-30 kDa) are used for separation to remove small molecule impurities and some pigments, while retaining large molecule polysaccharides and colloidal active components.
[0034] Step 5: Vacuum low-temperature concentration and spray drying The filtrate was concentrated under vacuum at a temperature below 55°C to a solid content of 15% to 25%, and then spray-dried at an inlet air temperature of 140 to 165°C and an outlet air temperature of 75 to 90°C to obtain water shield extract powder.
[0035] Innovations: Low-temperature compound enzymatic hydrolysis combined with segmented hot water extraction is used to increase the release rate of water shield polysaccharides; ultrafiltration membrane separation is used to reduce low-molecular-weight impurities and improve the applicability to cosmetics; low-temperature concentration and spray drying conditions are optimized to reduce the loss of heat-sensitive components.
[0036] 2. Innovative extraction process of Scutellaria baicalensis extract The main active components of Scutellaria baicalensis are flavonoids such as baicalin, baicalein, and wogonin. The method of "low-alcohol extraction-deep eutectic assisted extraction-macroporous resin enrichment" is suitable for improving the yield and purity of total flavonoids.
[0037] Process steps: Step 1: Raw material pretreatment After washing, the Scutellaria baicalensis root is dried at a temperature below 60°C and then pulverized and passed through a 40-mesh sieve.
[0038] Step 2: Eutectic solvent-assisted alcohol extraction Prepare a green eutectic solvent (such as a choline chloride-lactic acid system, molar ratio 1:2), add it to 50%-70% ethanol at a volume fraction of 5%-15%, and extract at a material-to-liquid ratio of 1:(8-12). Extract with ultrasound at 60-75℃ for 30-60 min.
[0039] Step 3: Reflux and secondary extraction The residue was then refluxed with 50%–70% ethanol 1–2 times, each time for 1.0–1.5 h, and the extracts were combined.
[0040] Step 4: Reduce pressure to recover ethanol Ethanol was recovered to a content of less than 10% under conditions of 45~55℃ and -0.08~-0.095 MPa.
[0041] Step 5: Macroporous resin enrichment Adsorption was performed using AB-8 or D101 macroporous resins, with the sample loading flow rate controlled at 1.0~2.0 BV / h. After washing with water to remove impurities, the sample was eluted with a gradient of 50%~80% ethanol to collect the flavonoid-rich fraction of Scutellaria baicalensis.
[0042] Step 6: Concentration and Drying The eluent was concentrated under reduced pressure and then dried under low temperature vacuum or spray-dried to obtain Scutellaria baicalensis extract powder.
[0043] Innovations include: using eutectic solvent-assisted extraction to improve flavonoid dissolution efficiency; combining ultrasound and reflux to shorten extraction time; and using macroporous resin for enrichment to improve flavonoid purity and compatibility stability.
[0044] 3. Innovative extraction process of ginseng extract The main active components in ginseng are ginsenosides, along with polysaccharides, amino acids, and small amounts of volatile compounds. To balance the activity of both saponins and polysaccharides, a low-temperature directional extraction and membrane separation process is employed.
[0045] Process steps: Step 1: Raw material pretreatment After ginseng is sliced, it is dried at low temperature and then pulverized and passed through a 20-40 mesh sieve.
[0046] Step 2: Gradient alcohol extraction Use 30%~60% ethanol as the extraction solvent, with a solid-liquid ratio of 1:(10~15), and reflux extraction at 50~65℃ for 1.5~2.5 h, for a total of 2 extractions.
[0047] Step 3: Ultrasonic Enhanced Extraction The second extraction can be performed with ultrasound assistance, using an ultrasound power of 200-500 W, a temperature of 45-60℃, and a time of 20-40 min, to promote saponin release.
[0048] Step 4: Membrane fractionation purification After merging the extracts, the fractions are separated by nanofiltration or ultrafiltration to preferentially retain the saponins and polysaccharide complex active components with relatively high molecular weight, while removing some pigments and small molecule impurities.
[0049] Step 5: Low-temperature concentration and freeze-drying After concentration at below 50°C, the extract was pre-frozen at -40°C and then freeze-dried under vacuum to obtain a highly active ginseng extract powder.
[0050] Innovations: Gradient alcohol extraction combined with ultrasonic enhancement improves saponin extraction rate; membrane fractionation purification improves component uniformity; freeze drying preserves ginseng's thermosensitive activity.
[0051] 4. Innovative extraction process of Atractylodes lancea extract The main active ingredients in Atractylodes lancea include atractylone, atractylol, and volatile oil components, which have oil-controlling, antibacterial, and skin-conditioning effects. The processing method must balance the retention of volatile components with the removal of irritating impurities.
[0052] Process steps: Step 1: Raw material pretreatment After cleaning, the rhizome of Atractylodes lancea is dried at low temperature and then pulverized and passed through a 20-40 mesh sieve.
[0053] Step 2: Supercritical CO2 extraction of volatile components Supercritical CO2 extraction was employed at a pressure of 20–30 MPa, a temperature of 35–45 °C, a CO2 flow rate of 15–30 kg / h, and an extraction time of 1.5–3 h. 5%–10% ethanol was used as an entrainer to improve the extraction efficiency of polar components.
[0054] Step 3: Secondary extraction with ethanol The residue was then refluxed with 60%~80% ethanol at a material-to-liquid ratio of 1:(8~12) 1~2 times, each time for 1~1.5 h, to obtain Atractylodes polyphenols and auxiliary active ingredients.
[0055] Step 4: Low-temperature solvent removal and standardization After combining the extracts, the concentration was carried out under reduced pressure to control the final volatile oil content and total solids content. If necessary, microencapsulation or cyclodextrin inclusion treatment was performed to improve stability and odor compatibility.
[0056] Innovations: Supercritical CO2 is used to preferentially extract volatile active ingredients, avoiding high-temperature loss; secondary ethanol extraction retains auxiliary active ingredients; further encapsulation can be performed to improve applicability in cosmetics.
[0057] 5. Innovative extraction process of licorice extract The main active ingredients in licorice are glycyrrhizic acid, glycyrrhetinic acid, and glycyrrhizin flavonoids, which have soothing, anti-inflammatory, and antioxidant effects.
[0058] Process steps: Step 1: Raw material pretreatment Licorice root and stem are washed, dried, and pulverized through a 40-mesh sieve.
[0059] Step 2: Acid-base regulation - combined water and alcohol extraction Add the raw material to 40%~60% ethanol at a material-to-liquid ratio of 1:(10~15), add 0.05%~0.20% citric acid or lactic acid to adjust the pH of the system to 5.0~6.0, and reflux extract at 55~70℃ for 1~2 h.
[0060] Step 3: Ultrasonic-assisted extraction Ultrasound was applied during the extraction process at a power of 150-400 W for 20-45 min to enhance the dissolution of glycyrrhizic acid and flavonoids.
[0061] Step 4: Macroporous resin enrichment and decolorization Adsorption was performed using AB-8, HPD-100 or XAD series macroporous resins. Sugar impurities were first removed by washing with water, and then eluted with 40%~75% ethanol to obtain a component rich in glycyrrhizic acid and flavonoids.
[0062] Step 5: Concentration and Drying The licorice extract was obtained by concentration under reduced pressure and vacuum drying.
[0063] Innovations: The acid-base micro-regulation water-alcohol extraction method improves the extraction efficiency of glycyrrhizic acid; the ultrasonic-assisted resin enrichment method balances purity and yield; and it is more suitable for mild and soothing applications in cosmetics.
[0064] The five extracts mentioned above possess the theoretical principle of synergistic effect of multiple skin care benefits. The synergistic effect of the multi-effect skin care composition of this invention mainly originates from the following mechanisms: (1) Synergistic effect of moisturizing and repair Water shield extract, rich in polysaccharides and colloidal components, can form a flexible moisturizing film on the skin surface, reducing transepidermal water loss (TEWL); the polysaccharides and saponins in ginseng extract can promote barrier repair and stratum corneum hydration; licorice extract helps soothe micro-inflammation caused by dryness and improves barrier stability. The combination of these three can form a closed loop of "moisturizing-repairing-soothing".
[0065] (2) Antioxidant synergy Flavonoids, ginsenosides, and licorice flavonoids in Scutellaria baicalensis all have the effect of scavenging free radicals and inhibiting lipid peroxidation; Polysaccharides from water shield can reduce oxidative stress exposure through protective film formation; and synergistic effects can enhance the skin's antioxidant defense system.
[0066] (3) Synergistic effect of soothing and anti-stimulation Baicalin and glycyrrhizic acid have typical soothing activities and can reduce redness and discomfort caused by external stimuli; the volatile components of Atractylodes lancea have an auxiliary effect on skin condition regulation and microecological balance; the combination can enhance the gentle and soothing experience of cosmetics.
[0067] (4) Oil control and skin cleansing synergistic effect Atractylodes lancea extract has good oil-controlling and skin-conditioning effects; Scutellaria baicalensis extract has the potential to improve sebum oxidation and oily environment; when combined with licorice, water shield, and ginseng, it can control oil while avoiding excessive dryness.
[0068] (5) Signal path coordination Scutellaria baicalensis flavonoids, glycyrrhizic acid, and ginsenosides can collectively influence pathways related to inflammatory responses, oxidative stress, and skin repair, such as NF-κB, MAPK, and Nrf2, thereby enhancing overall skincare efficacy.
[0069] In the herbal extract composition of the present invention, the preferred mass fraction ranges of each component are as follows: Water shield extract: 10-35 parts; Scutellaria baicalensis extract: 10-30 parts; Ginseng extract: 10-25 parts; Atractylodes lancea extract: 5-20 parts; Licorice extract: 10-30 parts When the total mass of the above five extracts is 100 parts, it can also be converted into their respective mass percentages.
[0070] The composition of the present invention can be applied to a variety of cosmetic systems, with an addition range of 0.2-8%, preferably 0.2-5%; or 0.5-3%.
[0071] The amounts added in different dosage forms of cosmetics are as follows: Toner / Serum: 0.2-5%; Lotion / Cream: 0.5-5%; Face Mask: 0.5-8%; Cleanser: 0.1-2%; Body Lotion and Repairing Skincare Products: 0.5-5%.
[0072] The following are examples of compounding processes for multi-effect skincare herbal extract compositions. The units for the following weight parts can be g or kg.
[0073] Example 1 Weigh out the following amounts by weight: 20 parts of water shield extract, 20 parts of scutellaria baicalensis extract, 20 parts of ginseng extract, 10 parts of atractylodes lancea extract, and 30 parts of licorice extract.
[0074] Process steps: Pass the extracts of water shield, scutellaria baicalensis, ginseng, atractylodes lancea, and licorice through an 80-mesh sieve to remove agglomerated particles; place the above raw materials in a stainless steel mixing tank and premix for 10 minutes at 40-45°C; turn on the stirring device and stir at a low speed of 300-500 rpm for 30 minutes; during this period, a small amount of dry nitrogen can be introduced or vacuum degassing can be used to remove entrained air; after stirring, cool to room temperature and pass through an 80-mesh sieve to obtain compound composition A.
[0075] Key points of the process: This embodiment uses isothermal low-shear mixing, which is suitable for use in conventional aqueous, emulsion and mask systems.
[0076] Example 2 Weigh out the following amounts by weight: 25 parts of water shield extract, 20 parts of scutellaria baicalensis extract, 18 parts of ginseng extract, 12 parts of atractylodes lancea extract, and 25 parts of licorice extract.
[0077] Process steps: Pass each extract through an 80-mesh sieve; add the water shield extract and ginseng extract to a mixing tank and premix at 45℃ for 15 min; add the scutellaria baicalensis extract, atractylodes lancea extract and licorice extract in sequence; stir at 350-600 rpm for 40 min; if necessary, add 0.5%-2.0% propylene glycol or 1,3-butanediol as a pre-wetting dispersion medium to improve the uniformity of powder dispersion; After mixing evenly, the mixture is cooled and sieved to obtain compound composition B.
[0078] Key points of the process: In this embodiment, the proportion of water shield and ginseng is relatively high, making it more suitable for moisturizing and repairing products.
[0079] Example 3 Weigh out the following amounts by weight: 25 parts of water shield extract, 18 parts of scutellaria baicalensis extract, 17 parts of ginseng extract, 15 parts of atractylodes lancea extract, and 25 parts of licorice extract.
[0080] Process steps: First, add licorice extract and ginseng extract to a premixing tank and premix at 40-45℃ for 15 min; add scutellaria extract and stir for 20 min; then add water shield extract and atractylodes extract, controlling the stirring speed at 400-700 rpm; continue stirring for 20-30 min; granulate the mixture through an 80-mesh sieve, and if necessary, vacuum dry at below 50℃ until the moisture content is ≤5%; to obtain compound composition C.
[0081] Key points of the process: This embodiment adopts a step-by-step addition method, which is beneficial to improve the flowability of powder and batch uniformity.
[0082] Example 4 Weigh out the following components by weight: 30 parts of water shield extract, 15 parts of scutellaria baicalensis extract, 20 parts of ginseng extract, 10 parts of atractylodes lancea extract, and 25 parts of licorice extract.
[0083] Process steps: Pre-wet the water shield extract with a small amount of humectant, preferably one or more of glycerin, 1,3-butanediol, and propylene glycol, at an amount of 5%–15% of the total extract; pre-disperse at 500–800 rpm for 10 min; sequentially add ginseng extract, licorice extract, scutellaria baicalensis extract, and atractylodes lancea extract; emulsify and disperse using an emulsifying shear disperser at 1000–1500 rpm for 15 min; then transfer to a vacuum degassing tank and degas at -0.06–-0.09 MPa for 5–10 min; after cooling, obtain compound composition D.
[0084] Key process points: Pre-wetting treatment can significantly improve the moisture absorption and clumping problem of water shield polysaccharide powder, making it suitable for high moisture retention formulation systems.
[0085] Example 5 Weigh out the following components by weight: 18 parts of water shield extract, 22 parts of scutellaria baicalensis extract, 20 parts of ginseng extract, 12 parts of atractylodes lancea extract, and 28 parts of licorice extract.
[0086] Process steps: Add all extracts to a high-speed shear dispersion vessel; shear disperse at 1000-3000 rpm for 10-15 min; then switch to low-speed homogenization mode at 300-600 rpm and continue homogenization for 20 min; control the system temperature below 45℃ to avoid heat loss of active ingredients; if the system contains hygroscopic components, 0.5%-3% silica or microcrystalline cellulose can be added to improve powder stability; after mixing evenly, pass through an 80-mesh sieve to obtain compound composition E.
[0087] Processing points: This embodiment is suitable for obtaining compositions with superior flowability and stability, and can be used in liquid and gel systems.
[0088] The following are the effect test examples of the compound compositions AE in Examples 1-5. The following tests were used to verify the synergistic effect of the compositions of the present invention.
[0089] Experimental Example 1: Synergistic Experiment of DPPH Free Radical Scavenging Experimental methods: The scavenging rates of DPPH free radicals by individual samples of water shield extract, scutellaria baicalensis extract, ginseng extract, atractylodes lancea extract, and licorice extract, as well as the compound composition AE, were determined.
[0090] The sample concentrations were set to 10, 25, 50, and 100 μg / mL. The results of DPPH radical scavenging rates (%) for different samples are shown in Table 1 below.
[0091] Table 1. DPPH radical scavenging rate (%) of different samples
[0092] The results in Table 1 show that the DPPH scavenging rate of the compound group at 50 μg / mL was significantly higher than the theoretical summation value of the monomers, indicating a significant synergistic effect.
[0093] Experimental Example 2: Hydroxyl Radical Scavenging Test Experimental method: The scavenging rate of each sample against hydroxyl radicals was determined using the Fenton system, with the concentrations as above.
[0094] The experimental results are shown in Table 2 below.
[0095] Table 2. Hydroxyl radical scavenging rate (%) of different samples
[0096] The results in Table 2 show that the scavenging rate of hydroxyl radicals in different samples of the compound group was significantly higher than the theoretical summation value of the monomers, indicating a significant synergistic effect.
[0097] Experimental Example 3: Human Skin Moisturizing and TEWL Improvement Trial Experimental method: Thirty subjects used an emulsion containing the composition of the present invention for 28 consecutive days, and the stratum corneum moisture content and transepidermal water loss (TEWL) were measured.
[0098] The experimental results are shown in Table 3 below.
[0099] Table 3 Changes in skin indicators after 28 days of use.
[0100] The results in Table 3 show that the compound group has a more significant moisturizing and barrier repair effect than the single group.
[0101] Experiment Example 4: In Vitro Relaxation Model Experiment Experimental methods: A keratinocyte inflammation model was used to detect the expression of IL-6 and TNF-α.
[0102] The test results are shown in Table 4.
[0103] Table 4. Inhibition rate of inflammatory factors (%)
[0104] The results in Table 4 show that the compound group has a more significant inhibitory effect on inflammatory factors than the single group.
[0105] Experimental Example 5: Anti-inflammatory Activity Experiment Experimental methods: An LPS-induced RAW264.7 mouse macrophage inflammation model was used to detect the secretion of IL-6 and TNF-α. The concentration of the compound extract was 50 μg / mL.
[0106] The experimental results are shown in Table 5 below.
[0107] Table 5. Levels of inflammatory factors in the 50 μg / mL treatment group
[0108] The results in Table 5 show that all the compound compositions significantly inhibited the secretion of inflammatory factors, indicating that they have good anti-inflammatory and soothing effects.
[0109] Experimental Example 6: Antioxidant Capacity Analysis Experimental method: Determine the IC50 of the DPPH free radical scavenging experiment.
[0110] The experimental results are shown in Table 6 below.
[0111] Table 6 Comparison of DPPH IC50 of each sample
[0112] The results in Table 6 show that the IC50 of the compound extract was 25 μg / mL, which was about 30% lower than that of the single licorice extract, indicating a synergistic antioxidant effect.
[0113] Experiment 7: Cell Viability Promotion Experiment 1. Test Methods Human skin fibroblasts were cultured in vitro, and the cell proliferation rate was measured after adding various samples.
[0114] 2. Test Results Table Table 7. Promoting effect on human fibroblast proliferation
[0115] The results in Table 7 show that the compound composition can promote fibroblast proliferation, suggesting its potential to promote skin repair and regeneration.
[0116] Unless otherwise specified, the sum of the weight percentages of all components in the following formula is 100%.
[0117] Application Example 1: Moisturizing and Repairing Lotion The formula for this moisturizing and repairing lotion is as follows: Compound extract A 3.0%; propylene glycol 5.0%; sodium hyaluronate 0.10%; co-emulsifier 5.0%; glycerin 4.0%; squalane 6.0%; glyceryl stearate 2.0%; C12-15 benzoate 4.0%; purified water 75.9%; total 100.0%.
[0118] Preparation process: 1) Add purified water, propylene glycol, glycerin, sodium hyaluronate and compound extract A to an aqueous phase tank and stir at 70°C until completely dissolved; 2) Squalane, glyceryl stearate, C12-15 benzoyl alcohol and auxiliary emulsifier are added to the oil phase tank and heated to 70°C to mix evenly; 3) Slowly add the oil phase to the aqueous phase and homogenize using a homogenizer at 3000-6000 rpm for 3-5 minutes; 4) Cool down to below 45℃ and continue stirring for 15 minutes; vacuum degassing and then fill to obtain the moisturizing and repairing emulsion.
[0119] Application Example 2: Whitening and Antioxidant Essence The whitening and antioxidant serum's formula composition (%) is as follows: Compound extract B 5.0%; Vitamin C derivative 2.0%; Glycerin 4.0%; 1,3-Butanediol 5.0%; Sodium hyaluronate 0.10%; Xanthan gum 0.20%; Phenoxyethanol 0.80%; Disodium EDTA 0.05%; Purified water 82.85%; Total 100.0%.
[0120] Preparation process: 1) Add purified water to the mixing tank, then add disodium EDTA, glycerol, and 1,3-butanediol and stir to dissolve. 2) Add xanthan gum at 30-35℃ and stir until completely thickened; add compound extract B and vitamin C derivative in sequence and stir at low speed for 10-15 min. 3) Add phenoxyethanol preservative; adjust pH to 5.0-6.0; filter and fill in the dark to obtain whitening and antioxidant essence.
[0121] Application Example 3: Soothing and Repairing Mask The formula for this soothing and repairing mask consists of: Compound extract C 6.0%; Aloe vera gel 10.0%; Potassium glycyrrhizate 0.05%; Bentonite 3.0%; Glycerin 5.0%; 1,2-Hexanediol 1.0%; Carbomer 0.20%; Triethanolamine 0.15%; Purified water 74.60%; Total 100.0%.
[0122] Preparation process: 1) Add purified water to the main tank, add carbomer and disperse evenly; then add glycerin, 1,2-hexanediol, aloe vera gel, potassium glycyrrhizate and bentonite in sequence; 2) Add compound extract C at 30-40℃; adjust the pH to 5.3-5.8 with triethanolamine to form a uniform gel system; 3) After vacuum degassing, it is filled into sheet or paste mask base material.
[0123] Application Example 4: Anti-aging Cream The formula of the anti-aging cream is as follows: Compound extract A 4.0%; collagen hydrolysate 2.0%; squalane 6.0%; emulsifier 6.0%; glycerin 4.0%; stearyl alcohol 3.0%; cetyl alcohol 2.0%; retinol derivative 0.10%; preservative 0.80%; purified water 72.10%; total 100.0%.
[0124] Preparation process: 1) Prepare the oil phase and aqueous phase separately; dissolve the oil phase by heating at 75℃, and homogenize the aqueous phase by heating at 75℃; 2) Slowly add the aqueous phase to the oil phase and homogenize for 5 min at 5000 rpm using a homogenizer; after cooling to 45℃, add compound extract A, collagen hydrolysate and retinol derivative; 3) Continue stirring for 15 minutes, then degas and fill.
[0125] Application Example 5: Oil-Control and Refreshing Gel The formula for this oil-controlling and refreshing gel is as follows: Compound extract B 2.0%; Sodium hyaluronate 0.20%; Tea tree oil 0.50%; Hydrogel matrix 12.0%; Glycerin 4.0%; 1,2-Hexanediol 1.0%; Carbomer 0.30%; Triethanolamine 0.20%; Purified water 79.80%; Total 100.0%.
[0126] Preparation process: 1) Add purified water to the main tank, add carbomer and stir to disperse; then add glycerol, 1,2-hexanediol, sodium hyaluronate and hydrogel matrix in sequence; 2) Add compound extract B and stir at low speed for 10 min; separately, dissolve tea tree oil in a small amount of solubilizer before adding it to the main system; 3) Adjust the pH to 5.5-6.2 using triethanolamine; stir evenly at low temperature and defoam to obtain an oil-controlling and refreshing gel.
[0127] Cosmetic application efficacy test cases The following test examples are used to illustrate the effects of the compositions of the present invention, and the specific data can be used as experimental support in the specification.
[0128] Application Test Example 1: Moisturizing Efficacy Test 1) Experimental Design Subjects: 30 healthy volunteers, aged 22–45 years; Grouping: Randomized double-blind, with 15 participants in the control group and 15 participants in the experimental group; Control group: using a base emulsion without compound extracts; Experimental group: Using the emulsion from Application Example 1; Instructions for use: Use once in the morning and once in the evening for 4 consecutive weeks. Testing instrument: Corneometer skin moisture meter; Test areas: Average value of forehead and cheeks; Statistical method: Take the average value and calculate the relative improvement rate.
[0129] 2) Table data Table 8. Results of Moisturizing Efficacy Test
[0130] The results in Table 8 show that the skin moisture level of the experimental group increased significantly more than that of the control group, indicating that the compound extract of this invention has a significant moisturizing effect.
[0131] Application Test Example 2: Whitening and Antioxidant Efficacy Test 1) Experimental Design Subjects: 30 healthy volunteers, aged 22–45 years; Grouping: Randomized double-blind, with 15 participants in the control group and 15 participants in the experimental group; Control group: Using a basic serum without compound extracts; Experimental group: Using the serum from Application Example 2; Instructions for use: Use once in the morning and once in the evening for 6 consecutive weeks. Test indicators: Changes in melanin content; free radical scavenging rate (DPPH method or ABTS method); Statistical method: Take the mean and calculate the rate of change.
[0132] 2) Table data Table 9. Results of Whitening and Antioxidant Efficacy Tests
[0133] The results in Table 9 show that the melanin content in the experimental group decreased significantly more than that in the control group, and the free radical scavenging rate was significantly improved, indicating that the composition of the present invention has good whitening and antioxidant effects.
[0134] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Therefore, any simple modifications, equivalent changes, and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.
Claims
1. A multi-effect skincare herbal extract composition, characterized in that, It is composed of the following components in parts by mass: Water shield extract: 10-35 parts; Scutellaria baicalensis extract: 10-30 parts; Ginseng extract: 10-25 parts; Atractylodes lancea extract: 5-20 parts; Licorice extract: 10-30 parts.
2. The multi-effect skincare herbal extract composition as described in claim 1, characterized in that, It is composed of the following components in parts by mass: Water shield extract: 18-28 parts; Scutellaria baicalensis extract: 15-25 parts; Ginseng extract: 15-22 parts; Atractylodes lancea extract: 8-15 parts; Licorice extract: 15-25 parts.
3. The multi-effect skincare herbal extract composition as described in claim 1, characterized in that, It is composed of the following components in parts by mass: 25 parts of water shield extract; 20 parts of Scutellaria baicalensis extract; 18 portions of ginseng extract; 12 parts of Atractylodes lancea extract; 25 parts of licorice extract.
4. The multi-effect skincare herbal extract composition according to any one of claims 1-3, characterized in that: Each extract was premixed at 40-50°C for 20 min, and then dispersed at low speed of 300-500 rpm for 30 min to obtain the compound composition.
5. The multi-effect skincare herbal extract composition according to any one of claims 1-3, characterized in that: The extraction process steps of the water shield extract are as follows: Step 1: Raw material pretreatment Remove impurities from fresh or dried water shield raw materials, wash them, dry them at a low temperature of 40~50℃ until the moisture content is ≤10%, and then crush them through a 40~60 mesh sieve; Step 2: Low-temperature complex enzymatic hydrolysis Add purified water at a material-to-liquid ratio of 1:(12~18), adjust the pH to 4.8~5.5, add a compound enzyme (cellulase: pectinase = 1:1, the total enzyme content is 0.8%~1.5% of the raw material mass), and enzymatically hydrolyze at 45~52℃ for 1.5~3.0 h to break the cell wall and release polysaccharides and gums. Step 3: Segmented hot water extraction After enzymatic hydrolysis, the temperature is raised to 75~85℃ for two-stage hot water extraction: first extraction: material-to-liquid ratio 1:(10~12), extraction time 1.0~1.5 h; second extraction: material-to-liquid ratio 1:(8~10), extraction time 0.8~1.2 h, and the extracts are combined. Step 4: Membrane separation and purification Ultrafiltration membrane (molecular weight cutoff 10~30 kDa) is used for separation to remove small molecule impurities and some pigments, while retaining large molecule polysaccharides and colloidal active components; Step 5: Vacuum low-temperature concentration and spray drying The filtrate was concentrated under vacuum at a temperature below 55°C to a solid content of 15% to 25%, and then spray-dried at an inlet air temperature of 140 to 165°C and an outlet air temperature of 75 to 90°C to obtain water shield extract powder.
6. The multi-effect skincare herbal extract composition according to any one of claims 1-3, characterized in that: The extraction process steps of the Scutellaria baicalensis extract are as follows: Step 1: Raw material pretreatment After washing, the Scutellaria baicalensis root is dried at a temperature below 60°C, then pulverized and passed through a 40-mesh sieve. Step 2: Eutectic solvent-assisted alcohol extraction Prepare a green eutectic solvent (choline chloride-lactic acid system, molar ratio 1:2), add 5%~15% by volume to 50%~70% ethanol, extract at a material-liquid ratio of 1:(8~12), and perform ultrasonic-assisted extraction at 60~75℃ for 30~60 min. Step 3: Reflux and secondary extraction The residue was then refluxed with 50%–70% ethanol 1–2 times, each time for 1.0–1.5 h, and the extracts were combined. Step 4: Reduce pressure to recover ethanol Ethanol was recovered to a content of less than 10% under conditions of 45~55℃ and -0.08~-0.095 MPa. Step 5: Macroporous resin enrichment Adsorption was performed using AB-8 or D101 macroporous resin, with the sample loading flow rate controlled at 1.0~2.0 BV / h. After washing with water to remove impurities, the sample was eluted with a gradient of 50%~80% ethanol to collect the flavonoid-rich fraction of Scutellaria baicalensis. Step 6: Concentration and Drying The eluent was concentrated under reduced pressure and then dried under low temperature vacuum or spray-dried to obtain Scutellaria baicalensis extract powder.
7. The multi-effect skincare herbal extract composition according to any one of claims 1-3, characterized in that: The extraction process steps of the ginseng extract are as follows: Step 1: Raw material pretreatment After ginseng slices are dried at low temperature, they are pulverized and passed through a 20-40 mesh sieve. Step 2: Gradient alcohol extraction Use 30%~60% ethanol as the extraction solvent, with a solid-liquid ratio of 1:(10~15), and reflux extraction at 50~65℃ for 1.5~2.5 h, for 2 extractions; Step 3: Ultrasonic Enhanced Extraction The second extraction can be performed with ultrasound assistance, using an ultrasound power of 200-500 W, a temperature of 45-60℃, and a time of 20-40 min, to promote saponin release. Step 4: Membrane fractionation purification After combining the extracts, the extracts are fractionated by nanofiltration or ultrafiltration to preferentially retain saponins and polysaccharide complex active components with relatively high molecular weight, while removing some pigments and small molecule impurities. Step 5: Low-temperature concentration and freeze-drying After concentration at below 50°C, the extract was pre-frozen at -40°C and then freeze-dried under vacuum to obtain a highly active ginseng extract powder.
8. The multi-effect skincare herbal extract composition according to any one of claims 1-3, characterized in that: The extraction process steps of the Atractylodes lancea extract are as follows: Step 1: Raw material pretreatment After cleaning, the rhizome of Atractylodes lancea is dried at low temperature and then pulverized and passed through a 20-40 mesh sieve. Step 2: Supercritical CO2 extraction of volatile components Supercritical CO2 extraction was employed at a pressure of 20–30 MPa, a temperature of 35–45 °C, a CO2 flow rate of 15–30 kg / h, and an extraction time of 1.5–3 h. 5%–10% ethanol was used as an entrainer to improve the extraction efficiency of polar components. Step 3: Secondary extraction with ethanol The residue was then refluxed with 60%~80% ethanol at a material-to-liquid ratio of 1:(8~12) 1~2 times, each time for 1~1.5 h, to obtain Atractylodes polyphenols and auxiliary active ingredients; Step 4: Low-temperature solvent removal and standardization After combining the extracts, the concentration was carried out under reduced pressure to control the final volatile oil content and total solids content. If necessary, microencapsulation or cyclodextrin inclusion treatment was performed to improve stability and odor compatibility.
9. The multi-effect skincare herbal extract composition according to any one of claims 1-3, characterized in that: The extraction process steps of the licorice extract are as follows: Step 1: Raw material pretreatment Licorice root and stem are washed, dried, and pulverized through a 40-mesh sieve; Step 2: Acid-base regulation - combined water and alcohol extraction Add the raw material to 40%~60% ethanol at a material-to-liquid ratio of 1:(10~15), add 0.05%~0.20% citric acid or lactic acid to adjust the pH of the system to 5.0~6.0, and reflux extract at 55~70℃ for 1~2 h; Step 3: Ultrasonic-assisted extraction Ultrasound was applied during the extraction process at a power of 150-400 W for 20-45 min to enhance the dissolution of glycyrrhizic acid and flavonoids. Step 4: Macroporous resin enrichment and decolorization Adsorption was performed using AB-8, HPD-100 or XAD series macroporous resins. Sugar impurities were first removed by washing with water, and then eluted with 40%~75% ethanol to obtain a component rich in glycyrrhizic acid and flavonoids. Step 5: Concentration and Drying The licorice extract was obtained by concentration under reduced pressure and vacuum drying.
10. The application of the multi-effect skincare herbal extract composition according to claim 4 in the preparation of cosmetics, characterized in that: The herbal extract composition is present in the cosmetic at a mass percentage of 0.05-8% or 0.2-8%, with the remainder being conventional cosmetic excipients; the dosage forms of the cosmetic include moisturizing and repairing lotion, multi-effect repairing essence, repairing cream, soothing and repairing mask, oil-controlling conditioning gel, and anti-allergic soothing spray.