A hair care essence promoting melanin synthesis of the scalp and a preparation method thereof

Abstract

This invention provides a hair-nourishing essence that promotes scalp melanin synthesis and its preparation method, belonging to the field of cosmetic scalp care technology. This invention uses deer antler and Ganoderma lucidum to construct a nourishing base for replenishing Qi and blood, and combines it with bio-derived nano-melanin as the core active system, forming a three-layer synergistic mechanism of "replenishing Qi and blood and improving microcirculation - nourishing the hair follicle microenvironment - enhancing melanin synthesis": Deer antler extract replenishes Qi and blood, dilates scalp microvessels, and improves blood and oxygen supply to hair follicles; Ganoderma lucidum extract has antioxidant properties, repairs the hair follicle microenvironment, and delays melanocyte aging; nano-encapsulated bio-derived melanin penetrates into the hair follicle, replenishes melanin precursors, and activates tyrosinase, promoting the synthesis of melanin. The hair-nourishing essence prepared by this invention has a delicate texture, is easily absorbed, and is gentle and non-irritating. It can significantly enhance scalp tyrosinase activity, improve scalp microcirculation, and promote melanin synthesis. Long-term use can effectively improve gray hair and strengthen hair quality, making it suitable for people with insufficient Qi and blood and premature graying.

Description

Technical Field

[0001] This invention relates to the field of cosmetic scalp care technology, specifically to a hair nourishing essence that promotes scalp melanin synthesis and its preparation method. Background Technology

[0002] With increasing life pressure, irregular work and rest schedules, and blood and qi deficiency becoming more prominent, the number of people experiencing premature graying of hair is expanding year by year and showing a trend towards younger ages. Currently, hair-darkening products on the market are mainly divided into two categories: chemical dyeing and plant-based conditioning, both of which have significant technical shortcomings. Chemical dyeing only treats the symptoms, not the root cause, and causes serious damage: Most mainstream hair darkening products are chemical hair dyes, which develop color by oxidizing and depositing dye on the surface of the hair shaft. They can only cover up gray hair and cannot improve melanin synthesis from the root. Moreover, hair dyes contain aniline substances, which can easily irritate the scalp and damage the hair cuticle. Long-term use may lead to allergies, dry and brittle hair.

[0003] Single plant ingredients have weak effects and superficial effects: Some plant-based hair darkening products only add single extracts such as Polygonum multiflorum and Platycladus orientalis leaves, which only act on the surface of the scalp and cannot penetrate deep into the hair follicles to activate melanocytes; and ignore the fact that "insufficient Qi and blood" is the core cause of premature graying of hair in young and middle-aged people. Insufficient blood and oxygen supply to hair follicles and lack of raw materials for melanocyte synthesis make it difficult for simple melanin-promoting ingredients to play a role.

[0004] Without a foundation of replenishing Qi and blood, the root cause of gray hair cannot be addressed: Traditional Chinese medicine theory holds that "hair is the surplus of blood," and a deficiency of Qi and blood in the scalp can lead to insufficient nutrition for hair follicles and a decline in melanocyte function. Most existing products only target melanocytes themselves, failing to address the underlying issue of improving scalp microcirculation and replenishing Qi and blood, thus failing to solve the root cause of gray hair.

[0005] Melanin raw materials have poor permeability and are easily deactivated: Some products directly add melanin raw materials, but ordinary melanin molecules are large and difficult to penetrate the stratum corneum of the scalp to reach the hair follicles; moreover, the high-temperature emulsification process can easily lead to the degradation of active ingredients, and the actual efficacy of the final product is greatly reduced.

[0006] Poor formula texture and user experience: Most hair darkening products have a thick and sticky texture, leaving the scalp oily and prone to attracting dust after application, resulting in low consumer willingness to use them long-term.

[0007] Therefore, those skilled in the art have provided a hair-nourishing essence that promotes scalp melanin synthesis and its preparation method to solve the problems mentioned in the background art. Summary of the Invention

[0008] To address the shortcomings of existing technologies, this invention provides a hair-nourishing essence that promotes scalp melanin synthesis and its preparation method. Based on the design concept of "nourishing qi and blood as the foundation, promoting melanin production as the core, and strong penetration as the guarantee," it utilizes deer antler and Ganoderma lucidum to construct a qi and blood nourishing system, combined with nano-encapsulated bio-derived melanin, creating a hair-nourishing and darkening essence that works synergistically from the inside out and improves hair health at its root. This invention solves the following problems: 1. It solves the problem of chemical dyeing only treating the symptoms and not the root cause, and damaging the scalp and hair, achieving dye-free and fundamentally promoting melanin synthesis; 2. To address the issues of weak and superficial effects of single-ingredient products, a three-layer synergistic mechanism is constructed to improve gray hair problems through multiple targets; 3. To address the problem of neglecting the root cause of qi and blood deficiency, deer antler and lingzhi are used to replenish qi and blood and improve microcirculation, providing a material basis for melanin synthesis; 4. To address the issues of poor melanin permeability and easy inactivation at high temperatures, nano-encapsulation technology and low-temperature feeding process are adopted to ensure activity and absorption efficiency; 5. The formula has been optimized for skin feel and stability, creating a refreshing, easily absorbed, gentle, and non-irritating serum texture suitable for long-term daily use.

[0009] To achieve the above objectives, the present invention provides the following technical solution: A hair-nourishing essence that promotes melanin synthesis in the scalp, comprising, by weight percentage, 2.1% to 11.5% of a core active composition, 12.5% ​​to 28.0% of a skin care matrix excipient, and the balance being deionized water; The core active composition consists of 0.5%~3.0% deer antler extract, 1.0%~5.0% Ganoderma lucidum extract, and 0.6%~3.5% bio-derived melanin. Deer antler and Ganoderma lucidum form a base for replenishing qi and blood, improving scalp microcirculation and hair follicle nutrition supply, and working synergistically with bio-derived melanin to promote melanin synthesis in scalp hair follicles, thus improving premature graying of hair due to qi and blood deficiency.

[0010] Furthermore, the deer antler extract is a refined extract obtained by low-temperature water extraction and alcohol precipitation of deer antler, wherein the mass content of deer antler polypeptide is ≥5%; the Ganoderma lucidum extract is a water extract of Ganoderma lucidum fruiting body, wherein the mass content of Ganoderma lucidum polysaccharide is ≥10%; the bio-derived melanin is plant fermentation-type melanin encapsulated in nanoliposomes, with an average particle size of 100~200nm.

[0011] Furthermore, the skin care base excipients include 5.0%~15.0% moisturizer, 2.0%~6.0% emulsifier, 3.0%~8.0% skin moisturizer, 0.1%~0.5% thickener, 0.2%~1.0% soothing agent, 0.02%~0.1% chelating agent, and 0.5%~2.0% mild preservative system.

[0012] Furthermore, the moisturizer is at least two of glycerin, propylene glycol, sodium hyaluronate, and panthenol; the emulsifier is a combination of cetearyl oleate, sorbitan oleate, and PEG-40 stearate; and the emollient is at least two of squalane, jojoba oil, and isononyl isononanoate.

[0013] Furthermore, the system uses a citric acid-sodium citrate buffer system to adjust the pH value to 5.5~6.5, which is weakly acidic and compatible with the physiological environment of the scalp, reducing irritation while ensuring the stability of active ingredients.

[0014] Furthermore, a method for preparing a hair-nourishing essence that promotes scalp melanin synthesis includes the following steps: Step S1: Aqueous phase preparation Add deionized water, humectant, thickener, and chelating agent to an aqueous reaction vessel, stir and heat to 80-85°C, and continue stirring until the material is completely dissolved and free of agglomerated particles. Step S2: Oil phase preparation Add the emulsifier and emollient to the oil phase pot, stir and heat to 80-85℃, and heat to melt until a uniform and transparent oil phase is formed. Step S3: Emulsification and Homogenization The oil phase material is drawn into the aqueous phase pot, and the homogenization and emulsification process is started. The emulsification process is completed by keeping the mixture warm and stirring. Step S4: Low-temperature activation feeding Start the cooling process and wait until the system temperature drops below 45°C. Then, add the deer antler extract, Ganoderma lucidum extract, bio-derived melanin, soothing agent, and mild preservative system in sequence, and stir at low speed until completely dispersed. Step S5: Adjust the discharge value Continue cooling to room temperature, adjust the pH to 5.5-6.5 using a buffer system, let it stand to defoam, and then filter it through a 100-mesh filter to obtain the finished hair nourishing essence.

[0015] Furthermore, in step S3, the homogenization speed is controlled at 3000~3500 r / min, and the homogenization time is 5~8 min; after homogenization, the speed is switched to 150~200 r / min for low-speed stirring, and the mixture is kept at 80~85℃ for 15~20 min for maturation.

[0016] Furthermore, in step S4, the temperature of the entire system is strictly controlled below 45°C, the stirring speed is 100~150 r / min, and the stirring time is 10~15 min; high temperature and high shear are prohibited to avoid structural damage and inactivation of deer antler polypeptides, Ganoderma lucidum polysaccharides and melanin.

[0017] Furthermore, the average particle size of the hair nourishing essence milk product is ≤2μm, and it shows no stratification, precipitation, or discoloration after three cold and hot cycle tests at -15℃ to 45℃. Its shelf life is ≥18 months when stored at room temperature in a sealed container.

[0018] Furthermore, the hair nourishing essence is used to improve premature graying of hair due to insufficient blood and qi, decline in melanin function of hair follicles, poor scalp microcirculation, and dry and brittle hair. The method of use is to apply it to the scalp and massage gently, 1-2 times a day. Continuous use for more than 28 days can significantly improve the level of melanin synthesis and reduce the proportion of gray hair.

[0019] This invention provides a hair-nourishing essence that promotes melanin synthesis in the scalp and its preparation method. It has the following beneficial effects: 1. This invention provides a hair-nourishing essence that promotes scalp melanin synthesis and its preparation method. This method starts by replenishing qi and blood and improving microcirculation to activate the hair follicle's own melanin synthesis ability, rather than surface dyeing. The effect of improving gray hair is more lasting and natural. Moreover, the use of deer antler, Ganoderma lucidum and melanin in a three-layer synergistic effect has significantly higher tyrosinase activation rate, microcirculation improvement rate and gray hair improvement rate than single ingredients.

[0020] 2. This invention provides a hair nourishing essence that promotes melanin synthesis in the scalp and its preparation method. It uses natural plant and animal-derived ingredients, is free of chemical dyes and strong irritants, and is safe for sensitive scalps. Long-term use will not damage hair quality. It also uses nano-encapsulation technology to enhance melanin penetration and a low-temperature preparation process to protect the activity of peptides and polysaccharides, ensuring the efficacy of the hair nourishing essence.

[0021] 3. This invention provides a hair nourishing essence that promotes scalp melanin synthesis and its preparation method. The hair nourishing essence has a water-in-oil lightweight milk texture, is refreshing and non-sticky when applied, absorbs quickly without residue, and is convenient for daily use. In addition, its weak acidity is suitable for the scalp, and it contains no chemical dyes or strong irritating ingredients, making it friendly to sensitive scalps. Long-term use will not damage hair quality, balancing efficacy and safety. It can be produced using conventional daily chemical emulsification equipment, with clear parameters and stable batches, making it suitable for large-scale industrial production. Attached Figure Description

[0022] Figure 1 This is a flow chart of the preparation process of the hair nourishing essence lotion of the present invention; Figure 2 This is a schematic diagram of the three-layer synergistic melanin synthesis mechanism of the present invention. Detailed Implementation

[0023] The present invention will now be described in further detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and not intended to limit it. Furthermore, it should be noted that, for ease of description, the accompanying drawings show only the parts relevant to the present invention, and not all of the structures.

[0024] In the description of this invention, unless otherwise explicitly specified and limited, the terms "connected," "linked," and "fixed" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0025] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0026] In the description of this embodiment, the terms "upper," "lower," "right," etc., refer to the orientation or positional relationship shown in the accompanying drawings. They are used only for ease of description and simplification of operation, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the present invention. In addition, the terms "first" and "second" are used only for distinction in description and have no special meaning.

[0027] The technical solution of the present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0028] like Figures 1-2 As shown, an embodiment of the present invention provides a hair care essence that promotes the synthesis of melanin in the scalp, comprising, by weight percentage, 2.1% to 11.5% of a core active composition, 12.5% ​​to 28.0% of a skin care matrix excipient, and the remainder being deionized water; The core active composition consists of 0.5%~3.0% deer antler extract, 1.0%~5.0% Ganoderma lucidum extract, and 0.6%~3.5% bio-derived melanin. Deer antler and Ganoderma lucidum form a base for replenishing qi and blood, improving scalp microcirculation and hair follicle nutrition supply, and working synergistically with bio-derived melanin to promote melanin synthesis in scalp hair follicles, thus improving premature graying of hair due to qi and blood deficiency.

[0029] Core active components and mechanism of action: Deer antler extract (core for replenishing Qi and blood): Made from sika deer antler through low-temperature water extraction and alcohol precipitation, it is rich in antler polypeptides, various amino acids, bioactive trace elements, and growth factors. Its core functions are: It replenishes qi and blood, gently dilates scalp microvessels, improves scalp microcirculation, enhances the efficiency of blood oxygen and nutrient supply to hair follicles, and provides sufficient raw materials and energy for melanin synthesis. It nourishes hair follicle stem cells, delays hair follicle aging, improves hair follicle atrophy, and strengthens the foundation for hair growth. It enhances the scalp barrier function and improves the penetration and absorption efficiency of subsequent active ingredients.

[0030] Reishi extract (for hair follicle nourishment): A refined extract from the fruiting body of Ganoderma lucidum, rich in polysaccharides, triterpenoids, and nucleoside active ingredients. Its core function is: It eliminates free radicals on the scalp, resists oxidative stress, protects hair follicle melanocytes from oxidative damage, and maintains melanocyte activity; It repairs the microenvironment of hair follicles, enhances the immunity of hair follicles, and works synergistically with deer antler to consolidate the nourishing effect of qi and blood. Soothes sensitive scalp, reduces formula irritation, and is suitable for people with sensitive scalps.

[0031] Bio-derived nano-melanin (melanocyte-stimulating core): Natural melanin prepared through plant fermentation, processed using nanoliposome encapsulation technology, with an average particle size of 100-200 nm. Its core function is: Nanoparticles can penetrate the stratum corneum of the scalp to reach the hair follicles and directly replenish melanin precursor substances; It activates tyrosinase activity in hair follicles, enhances the ability of melanocytes to synthesize melanin, and promotes the production of endogenous melanin. It is evenly deposited in the hair shaft cortex, gradually improving the color of gray hair and achieving a natural blackening effect.

[0032] Triple synergistic effect mechanism: Qi and Blood-Hair Follicle Synergy: Deer antler improves microcirculation and increases blood oxygen supply, while Ganoderma lucidum repairs the microenvironment of hair follicles. Together, they provide a healthy working environment for melanocytes, solving the root cause problem of "insufficient Qi and Blood leading to insufficient melanin synthesis power". Endogenous-exogenous synergy: Deer antler and Ganoderma lucidum promote endogenous melanin synthesis, while nano-melanin supplements exogenous melanin precursors, working in two directions to achieve a hair-darkening effect far superior to a single approach. Synergistic Penetration-Absorption: Deer antler repairs the scalp barrier and enhances permeability, while nano-encapsulation technology ensures that melanin reaches the hair follicles, significantly improving the absorption efficiency of active ingredients.

[0033] The skincare base excipients include 5.0%~15.0% moisturizer, 2.0%~6.0% emulsifier, 3.0%~8.0% hydrating agent, 0.1%~0.5% thickener, 0.2%~1.0% soothing agent, 0.02%~0.1% chelating agent, and 0.5%~2.0% mild preservative system; The moisturizer is at least two of glycerin, propylene glycol, sodium hyaluronate, and panthenol; the emulsifier is a combination of cetearyl oleate, sorbitan oleate, and PEG-40 stearate; and the emollient is at least two of squalane, jojoba oil, and isononyl isononanoate.

[0034] Matrix system design: It adopts a gentle water-in-oil emulsion system, combined with multiple moisturizers and lightweight emollients to create a delicate, easy-to-spread, fast-absorbing, and non-sticky essence texture; it adds dipotassium glycyrrhizate and panthenol as soothing auxiliary ingredients to further reduce irritation; it uses a gentle preservative system of 1,2-hexanediol and p-hydroxyacetophenone, and is free of parabens and formaldehyde releasers; the pH is controlled at 5.5~6.5, which is slightly acidic and suitable for the physiological environment of the scalp.

[0035] The following examples are based on a total finished product weight of 1000g. All raw materials are cosmetic-grade compliant raw materials, and the preparation equipment is a general-purpose vacuum emulsification reactor. Efficacy testing is conducted using in vitro tyrosinase activity experiments, scalp microcirculation detection, and human trial evaluation. All tests comply with cosmetic safety and efficacy evaluation standards. Example 1:

[0036] This embodiment provides a hair-nourishing essence that promotes melanin synthesis in the scalp, comprising, by weight percentage, 5.5% of a core active composition, 12.5%~28.0% of a skin-care matrix excipient, and the remainder being deionized water; specifically: The core active composition consists of 1.5% deer antler extract, 2.5% Ganoderma lucidum extract, and 1.5% nano-bio-derived melanin. Deer antler and Ganoderma lucidum form a base for replenishing qi and blood, improving scalp microcirculation and hair follicle nutrition supply. Together with bio-derived melanin, they promote the synthesis of melanin in scalp hair follicles and improve premature graying of hair due to qi and blood deficiency. Moisturizers: Glycerin 6.0%, Propylene Glycol 3.0%, Sodium Hyaluronate 0.05%, Panthenol 1.0%; Emulsifiers: Cetearyl oleate 2.5%, Sorbitan oleate 1.5%; Emollients: Squalane 3.0%, Jojoba oil 2.0%; Thickener: Carbomer 0.2%; Soothing agent: Dipotassium glycyrrhizate 0.3%; Chelating agent: EDTA-2Na 0.05%; Preservative system: 1,2-hexanediol 0.8%, p-hydroxyacetophenone 0.3%; pH adjuster: Citric acid-sodium citrate buffer system in appropriate amount; Deionized water: Replenish to 100%; Finished product pH: 5.8.

[0037] The preparation process of this hair nourishing essence includes the following steps: Step S1: Aqueous phase preparation Add deionized water, glycerol, propylene glycol, sodium hyaluronate, panthenol, carbomer, and EDTA-2Na to the aqueous phase pot, start stirring at 200 r / min, heat to 82℃, and stir for 20 min until completely dissolved and free of particles. Step S2: Oil phase preparation Cetearyl alcohol olive oil ester, sorbitan olive oil ester, squalane, and jojoba oil are added to the oil phase pot, stirred and heated to 82°C, and melted until uniform and transparent; Step S3: Emulsification and Homogenization Slowly draw the oil phase into the aqueous phase pot, start the homogenizer, and homogenize at 3200 r / min for 6 min. After homogenization, switch to low speed stirring at 180 r / min and keep warm at 82℃ for 18 min. Step S4: Low-temperature feeding Turn on the cooling water to cool down. When the system temperature drops to 42℃, add deer antler extract, Ganoderma lucidum extract, nano-bio-derived melanin, dipotassium glycyrrhizate, 1,2-hexanediol and p-hydroxyacetophenone in sequence. Stir at low speed of 120r / min for 12min until the dispersion is uniform. Step S5: Adjust the discharge value Continue cooling to room temperature, adjust the pH to 5.8 using a buffer system, let stand for 30 minutes to defoam, filter through a 100-mesh filter to obtain the finished hair nourishing essence. Example 2:

[0038] This embodiment provides a hair-nourishing essence that promotes melanin synthesis in the scalp, comprising, by weight percentage, 2.1% core active composition, 12.5% ​​skin-care matrix excipients, and the remainder being deionized water; specifically: The core active composition consists of 0.5% deer antler extract, 1.0% Ganoderma lucidum extract, and 0.6% nano-bio-derived melanin. Deer antler and Ganoderma lucidum form a base for replenishing qi and blood, improving scalp microcirculation and hair follicle nutrition supply. Together with bio-derived melanin, they promote the synthesis of melanin in scalp hair follicles and improve premature graying of hair due to qi and blood deficiency. Moisturizers: Glycerin 6.0%, Propylene Glycol 3.0%, Sodium Hyaluronate 0.05%, Panthenol 1.0%; Emulsifiers: Cetearyl oleate 2.5%, Sorbitan oleate 1.5%; Emollients: Squalane 3.0%, Jojoba oil 2.0%; Thickener: Carbomer 0.2%; Soothing agent: Dipotassium glycyrrhizate 0.3%; Chelating agent: EDTA-2Na 0.05%; Preservative system: 1,2-hexanediol 0.8%, p-hydroxyacetophenone 0.3%; pH adjuster: Citric acid-sodium citrate buffer system in appropriate amount; Deionized water: Replenish to 100%; Finished product pH: 5.5.

[0039] The preparation process of this hair nourishing essence includes the following steps: Step S1: Aqueous phase preparation Add deionized water, glycerol, propylene glycol, sodium hyaluronate, panthenol, carbomer, and EDTA-2Na to the aqueous phase pot, start stirring at 200 r / min, heat to 82℃, and stir for 20 min until completely dissolved and free of particles. Step S2: Oil phase preparation Cetearyl alcohol olive oil ester, sorbitan olive oil ester, squalane, and jojoba oil are added to the oil phase pot, stirred and heated to 82°C, and melted until uniform and transparent; Step S3: Emulsification and Homogenization Slowly draw the oil phase into the aqueous phase pot, start the homogenizer, and homogenize at 3200 r / min for 6 min. After homogenization, switch to low speed stirring at 180 r / min and keep warm at 82℃ for 18 min. Step S4: Low-temperature feeding Turn on the cooling water to cool down. When the system temperature drops to 42℃, add deer antler extract, Ganoderma lucidum extract, nano-bio-derived melanin, dipotassium glycyrrhizate, 1,2-hexanediol and p-hydroxyacetophenone in sequence. Stir at low speed of 120r / min for 12min until the dispersion is uniform. Step S5: Adjust the discharge value Continue cooling to room temperature, adjust the pH to 5.5 using a buffer system, let stand for 30 minutes to defoam, and then filter through a 100-mesh filter to obtain the finished hair nourishing essence. Example 3:

[0040] This embodiment provides a hair-nourishing essence that promotes melanin synthesis in the scalp, comprising, by weight percentage, 11.5% core active composition, 28.0% skin-care matrix excipients, and the remainder being deionized water; specifically: The core active composition consists of 3.0% deer antler extract, 5.0% Ganoderma lucidum extract, and 3.5% nano-bio-derived melanin. Deer antler and Ganoderma lucidum form a base for replenishing qi and blood, improving scalp microcirculation and hair follicle nutrition supply. Together with bio-derived melanin, they promote the synthesis of melanin in scalp hair follicles and improve premature graying of hair due to qi and blood deficiency. Moisturizers: Glycerin 6.0%, Propylene Glycol 3.0%, Sodium Hyaluronate 0.05%, Panthenol 1.0%; Emulsifiers: Cetearyl oleate 2.5%, Sorbitan oleate 1.5%; Emollients: Squalane 3.0%, Jojoba oil 2.0%; Thickener: Carbomer 0.2%; Soothing agent: Dipotassium glycyrrhizate 0.3%; Chelating agent: EDTA-2Na 0.05%; Preservative system: 1,2-hexanediol 0.8%, p-hydroxyacetophenone 0.3%; pH adjuster: Citric acid-sodium citrate buffer system in appropriate amount; Deionized water: Replenish to 100%; Finished product pH: 6.5.

[0041] The preparation process of this hair nourishing essence includes the following steps: Step S1: Aqueous phase preparation Add deionized water, glycerol, propylene glycol, sodium hyaluronate, panthenol, carbomer, and EDTA-2Na to the aqueous phase pot, start stirring at 200 r / min, heat to 82℃, and stir for 20 min until completely dissolved and free of particles. Step S2: Oil phase preparation Cetearyl alcohol olive oil ester, sorbitan olive oil ester, squalane, and jojoba oil are added to the oil phase pot, stirred and heated to 82°C, and melted until uniform and transparent; Step S3: Emulsification and Homogenization Slowly draw the oil phase into the aqueous phase pot, start the homogenizer, and homogenize at 3200 r / min for 6 min. After homogenization, switch to low speed stirring at 180 r / min and keep warm at 82℃ for 18 min. Step S4: Low-temperature feeding Turn on the cooling water to cool down. When the system temperature drops to 42℃, add deer antler extract, Ganoderma lucidum extract, nano-bio-derived melanin, dipotassium glycyrrhizate, 1,2-hexanediol and p-hydroxyacetophenone in sequence. Stir at low speed of 120r / min for 12min until the dispersion is uniform. Step S5: Adjust the discharge value Continue cooling to room temperature, adjust the pH to 6.5 using a buffer system, let stand for 30 minutes to defoam, and filter through a 100-mesh filter to obtain the finished hair nourishing essence.

[0042] Comparative Example 1: Without deer antler extract The deer antler extract was removed, and the content and process of the remaining components were the same as in Example 1.

[0043] Comparative Example 2: Without Ganoderma lucidum extract The Ganoderma lucidum extract was removed, and the content and process of the remaining components were the same as in Example 1.

[0044] Comparative Example 3: Contains no nano-bio-derived melanin The nano-biological melanin was removed, and the content and process of the remaining components were the same as in Example 1.

[0045] Comparative Example 4: High-Temperature Feeding Process The formula is the same as in Example 1. Deer antler, Ganoderma lucidum and melanin are added during the emulsification stage at 82°C, and the rest of the process is the same.

[0046] Comparison Example 5: Commercially available common plant-based hair darkening essence The product is a mainstream plant-based hair darkening essence on the market, with its main ingredients being Polygonum multiflorum and Platycladus orientalis leaf extract, but it does not contain the ternary core system of this invention.

[0047] Performance testing: ① In vitro tyrosinase activity promotion test The tyrosinase-DOPA rate method was used to detect the enhancement rate of tyrosinase activity in each group of samples. A higher enhancement rate indicates a stronger ability to promote melanin synthesis. The detection results are shown in Table 1 below: Table 1 Comparison of Tyrosinase Activity Increase Rate Example 1 67.3% Example 2 38.5% Example 3 79.2% Comparative Example 1 28.7% Comparative Example 2 35.1% Comparative Example 3 19.4% Comparative Example 4 22.6% Comparative Example 5 16.8% Conclusion: The ternary compound of this invention has a significantly better tyrosinase activation effect than any single component, proving that the synergistic effect of the three components can greatly improve the efficiency of melanin synthesis; high-temperature feeding will severely damage the active ingredients, resulting in a significant decrease in efficacy.

[0048] ② Scalp microcirculation improvement test Thirty volunteers were recruited and divided into groups to apply corresponding samples. Scalp blood flow was measured before and 30 minutes after application using a laser Doppler flowmeter. The blood flow enhancement rate was calculated, and the results are shown in Table 2 below. Table 2 Comparison of Scalp Blood Flow Increase Rate Example 1 42.6% Comparative Example 1 12.3% Comparative Example 2 30.5% Comparative Example 3 35.8% Comparative Example 5 8.7% Conclusion: Deer antler is the core component for improving scalp microcirculation, while Ganoderma lucidum assists in enhancing it. The combined effect of these two components to replenish qi and blood can significantly improve scalp blood oxygen supply, providing sufficient nutrition for melanin synthesis.

[0049] ③ Human trial test to improve gray hair Seventy volunteers with premature graying due to blood and qi deficiency were recruited and randomly divided into seven groups. The corresponding sample was applied twice daily, morning and evening, for 28 consecutive days. The rate of reduction in gray hair percentage was statistically analyzed using professional image analysis, and the effectiveness rate was also determined. The results are shown in Table 3 below. Table 3 Comparison of the Decline Rate of Gray Hair Percentage Example 1 23.7% 80.0% Comparative Example 1 9.2% 30.0% Comparative Example 2 12.5% 40.0% Comparative Example 3 7.8% 25.0% Comparative Example 4 8.1% 20.0% Comparative Example 5 6.4% 20.0% Conclusion: No adverse reactions such as scalp redness, itching, or irritation were observed in any of the volunteers during the testing period, proving that the formula of this invention is mild and safe.

[0050] ④ Stability test The samples in Example 1 were subjected to a cold and hot cycling test (-15℃~45℃, 24h each time, 3 cycles) and a high temperature accelerated test (45℃, 30 days). The results showed that the samples did not separate, break down, change color, or precipitate, and the odor did not change. The melanin retention rate was ≥92%, proving that the product has excellent stability.

[0051] By comparing the results above, we can conclude that 1. The ternary compound system of deer antler, Ganoderma lucidum and melanin of this invention achieves significant synergistic effects in three dimensions: promoting melanin synthesis, improving microcirculation and improving gray hair. The effect is far superior to that of single ingredients and ordinary commercial products, which verifies the scientific nature of the design concept of "replenishing qi and blood base + promoting melanin core".

[0052] 2. Low-temperature preparation process is the key to ensuring activity. High-temperature feeding will lead to a significant decrease in efficacy. Feeding at temperatures below 45°C can maximize the preservation of the bioactivity of peptides, polysaccharides and melanin.

[0053] 3. Optimal Example 1 has a balanced formula, outstanding efficacy, refreshing feel, gentle and non-irritating properties, and good stability, and can be used as a benchmark formula for mass production.

[0054] The plant and animal extracts, nano-melanin, and matrix raw materials used in this invention are all compliant raw materials commonly used in the cosmetics industry, with wide procurement channels and controllable costs. The preparation process can be completed using a conventional vacuum emulsification reactor, without the need for special customized equipment. The process parameters are precise and controllable, and the batch-to-batch differences in mass production are small. The product can be used as a hair-nourishing and hair-darkening essence, scalp care lotion, and hair loss prevention and hair growth auxiliary product. It is suitable for multiple channels such as daily chemical brands, professional hair care institutions, and salon care. It has broad market demand for people with premature graying hair due to insufficient Qi and blood, and has extremely strong industrial production and commercial promotion value.

[0055] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

Claims

1. A hair-nourishing essence that promotes melanin synthesis in the scalp, characterized in that, By weight percentage, it comprises 2.1% to 11.5% core active composition, 12.5% ​​to 28.0% skin care matrix excipients, and the balance being deionized water; The core active composition consists of 0.5%~3.0% deer antler extract, 1.0%~5.0% Ganoderma lucidum extract, and 0.6%~3.5% bio-derived melanin. Deer antler and Ganoderma lucidum form a base for replenishing qi and blood, improving scalp microcirculation and hair follicle nutrition supply, and working synergistically with bio-derived melanin to promote melanin synthesis in scalp hair follicles, thus improving premature graying of hair due to qi and blood deficiency.

2. The hair-nourishing essence lotion that promotes scalp melanin synthesis according to claim 1, characterized in that, The deer antler extract is a refined extract obtained by low-temperature water extraction and alcohol precipitation of deer antler, wherein the mass content of deer antler polypeptide is ≥5%; the Ganoderma lucidum extract is a water extract of Ganoderma lucidum fruiting body, wherein the mass content of Ganoderma lucidum polysaccharide is ≥10%; the bio-derived melanin is plant fermentation-type melanin encapsulated in nanoliposomes, with an average particle size of 100~200nm.

3. The hair-nourishing essence lotion for promoting scalp melanin synthesis according to claim 1, characterized in that, The skin care base excipients include 5.0%~15.0% moisturizer, 2.0%~6.0% emulsifier, 3.0%~8.0% skin moisturizer, 0.1%~0.5% thickener, 0.2%~1.0% soothing agent, 0.02%~0.1% chelating agent, and 0.5%~2.0% mild preservative system.

4. The hair-nourishing essence lotion that promotes scalp melanin synthesis according to claim 3, characterized in that, The moisturizer is at least two of glycerin, propylene glycol, sodium hyaluronate, and panthenol; the emulsifier is a combination of cetearyl oleate, sorbitan oleate, and PEG-40 stearate; and the emollient is at least two of squalane, jojoba oil, and isononyl isononanoate.

5. The hair-nourishing essence lotion that promotes scalp melanin synthesis according to claim 1, characterized in that, The hair nourishing essence system uses a citric acid-sodium citrate buffer system to adjust the pH value to 5.5~6.5, which is weakly acidic and compatible with the physiological environment of the scalp, reducing irritation while ensuring the stability of active ingredients.

6. A method for preparing a hair-nourishing essence that promotes scalp melanin synthesis, characterized in that, Includes the following steps: Step S1: Aqueous phase preparation Add deionized water, humectant, thickener, and chelating agent to an aqueous reaction vessel, stir and heat to 80-85°C, and continue stirring until the material is completely dissolved and free of agglomerated particles. Step S2: Oil phase preparation Add the emulsifier and emollient to the oil phase pot, stir and heat to 80-85℃, and heat to melt until a uniform and transparent oil phase is formed. Step S3: Emulsification and Homogenization The oil phase material is drawn into the aqueous phase pot, and the homogenization and emulsification process is started. The emulsification process is completed by keeping the pot warm and stirring. Step S4: Low-temperature activation feeding Start the cooling process and wait until the system temperature drops below 45℃. Then, add the deer antler extract, Ganoderma lucidum extract, bio-derived melanin, soothing agent, and mild preservative system in sequence, and stir at low speed until completely dispersed. Step S5: Adjust the discharge value Continue cooling to room temperature, adjust the pH to 5.5-6.5 using a buffer system, let it stand to defoam, and then filter it through a 100-mesh filter to obtain the finished hair nourishing essence.

7. The method for preparing the hair-nourishing essence lotion that promotes scalp melanin synthesis according to claim 6, characterized in that, In step S3, the homogenization speed is controlled at 3000~3500 r / min, and the homogenization time is 5~8 min. After homogenization, the speed is switched to 150~200 r / min for low-speed stirring, and the mixture is kept at 80~85℃ for 15~20 min for maturation.

8. The method for preparing the hair-nourishing essence lotion that promotes scalp melanin synthesis according to claim 6, characterized in that, In step S4, the temperature of the system is strictly controlled below 45°C throughout the entire process of feeding the active component, the stirring speed is 100~150r / min, and the stirring time is 10~15min. High temperature and high shear are prohibited to avoid structural damage and inactivation of deer antler polypeptides, Ganoderma lucidum polysaccharides and melanin.

9. The hair-nourishing essence lotion for promoting scalp melanin synthesis according to claim 1, characterized in that, The hair nourishing essence milk product has an average particle size of ≤2μm, and after three cold and hot cycle tests at -15℃ to 45℃, it shows no stratification, no precipitation, and no discoloration. Its shelf life is ≥18 months when stored at room temperature in a sealed container.

10. The application of the hair-nourishing essence lotion that promotes scalp melanin synthesis according to claim 1, characterized in that, It is used to improve premature graying of hair due to insufficient Qi and blood, decline in melanin function of hair follicles, poor scalp microcirculation, and dry and brittle hair. The method of use is to apply it to the scalp and massage gently, 1-2 times a day. Continuous use for more than 28 days can significantly improve the level of melanin synthesis and reduce the proportion of gray hair.

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