A beauty and sleep-aiding herbal liqueur and a preparation method thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- LONGCAOHEYUAN (SHAANXI) BIOTECHNOLOGY CO LTD
- Filing Date
- 2026-05-06
- Publication Date
- 2026-08-04
AI Technical Summary
单纯的功能叠加无法实现协同效应,导致产品综合价值有限,难以满足消费者日益增长的复合型健康需求;
(1)本发明将药材深度整合到发酵剂药曲中,使药材从“被作用对象”转变为“发酵过程的参与者与引导者”,从根本上改变了传统工艺中发酵与功能分离的弊端;
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Abstract
Description
Technical Field
[0001] This invention belongs to the field of health food technology, specifically relating to a beauty-enhancing and sleep-aiding herbal liqueur and its preparation method. Background Technology
[0002] With the fast pace of modern life, the coexistence of sleep disorders and skin aging is becoming increasingly prominent, creating an urgent market demand for multifunctional health products that can simultaneously regulate internal functions and improve external appearance. Herbal liqueurs, as a food form that combines the functions of a carrier and a synergist, have become an ideal choice for developing such multifunctional products. However, existing herbal liqueur products and related preparation technologies have significant shortcomings in terms of efficacy synergy, process efficiency, and quality control, as detailed below: (1) The efficacy system is singular and lacks synergistic design. Existing products mostly focus on satisfying a single health demand. For example, patent document CN117815336A mainly focuses on improving the antioxidant capacity of the product, while CN114947074A focuses on improving sleep. This "single-point" R&D approach fails to explore and utilize the inherent physiological connection and synergistic potential between "internal nourishment of the spirit" (improving sleep) and "external nourishment of the face" (beauty and skin care) from the perspective of the "holistic view" of traditional Chinese medicine and modern "systems biology". The simple superposition of functions cannot achieve synergistic effect, resulting in limited comprehensive value of the product and difficulty in meeting the increasingly complex health needs of consumers; (2) The preparation process is crude and the conversion efficiency of the target is low. The current mainstream preparation process has a bottleneck. On the one hand, the traditional soaking process (such as CN117815336A) is essentially a physical extraction process. The active ingredients only undergo dissolution and migration, and there is a lack of chemical transformation mediated by biological enzymes or microorganisms. This not only limits the extraction efficiency, but also fails to generate new highly active metabolites (such as converting precursor substances into ferulic acid through fermentation), resulting in insufficient product efficacy. On the other hand, although existing fermented liqueurs (such as CN104524424A) have introduced a conversion process, they mostly use general-purpose yeast, have short fermentation cycles and inaccurate temperature control, and fail to design "directed fermentation" processes for the target efficacy components (such as specific glycosides and polysaccharides) in specific herbal formulas. Their conversion process has a lot of randomness, and the enrichment efficiency of the target components is low and unstable. (3) Poor coupling between formulation and process. Most existing technical solutions tend to oversimplify the process design by "one-pot cooking," that is, treating medicinal materials with different physicochemical properties (water-soluble / alcohol-soluble, heat-sensitive / stable) under the same process conditions. This design ignores the optimal dissolution medium, the optimal extraction temperature, and the ideal form for participating in subsequent fermentation stages of different active ingredients (for example, some components are suitable as fermentation substrates, while others are suitable for addition after fermentation to maintain activity). This disconnect between process and material characteristics not only causes the loss or destruction of some effective ingredients, but also easily leads to flavor incoordination and even the generation of undesirable byproducts, seriously affecting the final quality, safety, and efficacy stability of the product.
[0003] Therefore, existing technologies, both conceptually and practically, are insufficient to support the development of a high-quality, multifunctional herbal liqueur with clearly defined synergistic effects, advanced and controllable processes, stable and consistent quality, and scientific verification. Summary of the Invention
[0004] To address the shortcomings of existing technologies, this invention provides a beauty-enhancing and sleep-aiding herbal liqueur and its preparation method. By preparing a compound medicinal starter suitable for the beauty-enhancing and sleep-aiding herbal liqueur, and using the compound medicinal starter as a functional fermentation engine, a new dual-effect fermentation process combining "directional base wine fermentation" and "secondary fermentation of extract" is constructed. The resulting beauty-enhancing and sleep-aiding herbal liqueur has a good flavor and strong palatability, and can simultaneously meet the two major needs of internal sleep regulation and external skin improvement.
[0005] A beauty-enhancing and sleep-aiding herbal liqueur comprises the following raw materials in parts by weight: 100 parts rice, 15-32 parts a first herbal composition, and 98-137 parts a second herbal composition; it also comprises a compound medicinal yeast, wherein the mass of the compound medicinal yeast is 0.28-0.32% of the mass of the rice; The first herbal composition consists of the following raw materials in parts by weight: 4-6 parts Polygonatum sibiricum, 2-4 parts Rehmannia glutinosa, 2-4 parts Dioscorea opposita, 1-3 parts Cornus officinalis, 2-4 parts Poria cocos, 1-3 parts Lycium barbarum, 1-2 parts Ziziphus jujuba var. spinosa, 1-3 parts Ziziphus jujuba, and 1-3 parts Morus alba. The second herbal composition consists of the following raw materials in parts by weight: 28-32 parts Rehmannia glutinosa, 18-22 parts Cornus officinalis, 8-12 parts Polygonatum odoratum, 8-12 parts Rosa rugosa, 6-9 parts Angelica sinensis, 5-7 parts longan pulp, 2-4 parts dried tangerine peel, 2-4 parts Amomum villosum, 3-5 parts ginseng, 3-5 parts Astragalus membranaceus, 2-4 parts Eucommia ulmoides leaf, 3-5 parts Lycium barbarum, and 2-4 parts Euryale ferox.
[0006] Preferably, the compound medicinal starter comprises the following raw materials: wheat flour, core active ingredient, traditional auxiliary ingredients, active medicinal materials, and Polygonum hydropiper activator; the core active ingredient, traditional auxiliary ingredients, active medicinal materials, and Polygonum hydropiper activator account for 2.3-3.2%, 1.1-1.4%, 2.2-3.1%, and 30-40% of the mass content of the wheat flour, respectively. The core active ingredient is composed of the following raw materials in parts by weight: Angelica sinensis 60-90 parts, Gardenia jasminoides 60-80 parts, Salvia miltiorrhiza 60-80 parts, and Ligusticum chuanxiong 50-70 parts; The traditional adjuvant is composed of the following raw materials in parts by weight: Astragalus membranaceus 15-20 parts, Eucommia ulmoides leaves 15-20 parts, Glycyrrhiza uralensis 20-25 parts, Poria cocos 20-25 parts, Atractylodes macrocephala 20-25 parts, and Codonopsis pilosula 20-25 parts. The medicinal materials with efficacy are composed of the following raw materials in parts by weight: 45-55 parts of Polygonatum sibiricum, 40-55 parts of jujube, 40-55 parts of wolfberry, 25-35 parts of longan pulp, 25-35 parts of yam, 25-35 parts of hawthorn, 15-25 parts of mulberry, and 5-15 parts of kudzu root. The red knotweed activator is prepared by the following method: add 8-12 times the amount of water to the whole red knotweed herb, decoct for 1-2 hours, filter, and the resulting filtrate is the red knotweed activator.
[0007] The preparation method of the beauty-enhancing and sleep-aiding herbal liqueur includes the following steps: (a) Preparation of compound medicinal starter; (II) Preparation of base liquor: Mix rice and the first herbal composition, steam for 40-50 minutes, cool to room temperature, add the compound medicinal yeast, mix and stir evenly, add purified water to adjust the total water content to 56-60%, ferment at (18-20) ±0.5℃ for 40-45 days, then ferment at (15-17) ±1℃ for 40-45 days, press, clarify, remove sediment to obtain base liquor; (III) Preparation of efficacy extract: The different raw materials in the second herbal composition are divided into two groups, and water extraction and alcohol extraction are used for group extraction respectively. The extract obtained by water extraction is mixed with the extract obtained by alcohol extraction, and the volume is adjusted with purified water to 0.05-0.1 times the volume of the base wine to obtain efficacy extract; (iv) Secondary fermentation: Mix the base wine with the efficacy extract, add active dry yeast for wine, and ferment at (16-22)±0.5℃ for 10-30 days; (v) Post-processing: Sterilize, centrifuge, add clarifying agent, stand for 7-10 days, age the supernatant at (15-16)±0.5℃ for 4 months, filter finely, and aseptically fill.
[0008] Preferably, the preparation of the composite medicinal formula includes the following steps: (1) Raw material preparation: slice Angelica sinensis, crush raw materials other than Angelica sinensis, traditional auxiliary drugs and functional medicinal materials in the core main drug, and then mix them with sliced Angelica sinensis to obtain a mixture of Chinese medicinal materials for medicinal fermentation; (2) Mixing and molding: Mix the wheat flour, medicinal koji, and red knotweed activator, stir, press and mold to obtain koji blocks; (3) Gradual drying: The koji blocks are dried in an environment where the temperature and relative humidity decrease in sequence. Finally, they are aged for no less than 40 days at a temperature of 16±1℃ and a relative humidity of 55±2%. During the aging period, they are turned over, crushed, and vacuum packaged.
[0009] Preferably, in step (3), the gradient drying process is as follows: the gluten blocks are first dried and aged in an environment with a temperature of 19±1℃ and a relative humidity of 60±2% for 3-5 days, then dried in an environment with a temperature of 17±1℃ and a relative humidity of 58±2% for 3-5 days, and then dried in an environment with a temperature of 15±1℃ and a relative humidity of 55±2% for 3-5 days.
[0010] Preferably, in step (2), the density of the curved block is (1.1-1.4) ± 0.01 g / cm³. 2 .
[0011] Preferably, in step (ii), when fermenting at (18-20)±0.5℃, the mixture is stirred once every 5-6 days, and when fermenting at (15-17)±1℃, the mixture is stirred once every 9-10 days.
[0012] Preferably, in step (iii), the raw materials are grouped and extracted as follows: Rehmannia glutinosa, Cornus officinalis, Polygonatum odoratum, Polygonatum sibiricum, Angelica sinensis, longan pulp, ginseng, Astragalus membranaceus, Eucommia ulmoides leaves, and Euryale ferox are divided into group A; Rose, Citrus reticulata peel, Amomum villosum, and Lycium barbarum are divided into group B; group A is extracted with water, and group B is extracted with alcohol.
[0013] Preferably, the water extraction is performed as follows: add 8-10 times the mass of water to the raw materials in group A, and extract ultrasonically at 80-85℃ for 40-45 minutes. Repeat the ultrasonic extraction twice. Filter, concentrate the filtrate, and obtain the extract. The alcohol extraction is performed as follows: add 8-10 times the mass of ethanol to the raw materials in group B, and extract ultrasonically at 60-65℃ for 40-45 minutes. Repeat the ultrasonic extraction twice. Recover the ethanol to obtain the extract.
[0014] Preferably, the amount of active dry yeast added to the wine is 100-200 mg / L; the clarifying agent is bentonite, and the amount of the clarifying agent added accounts for 0.05-0.15% of the mass of the substance to be clarified.
[0015] Advantages of this invention: (1) This invention deeply integrates medicinal materials into the fermentation agent, transforming the medicinal materials from "the object of action" to "the participant and guide of the fermentation process", fundamentally changing the drawback of separating fermentation and function in traditional processes; (2) By adjusting the volume of the functional liquid, product series with different flavor and efficacy focuses can be produced, which meets the diversified needs of the market and has extremely high process flexibility. (3) The process of preparing liqueur in this invention, from the incorporation of medicinal materials into the starter culture, preparation of base liquor, preparation of efficacy extract and secondary fermentation, each process is designed with fine-grained process for the characteristics of medicinal materials, ensuring the maximum retention and transformation of active ingredients; when preparing base liquor, low-temperature long-time fermentation gives it a mellow and smooth taste, and secondary fermentation further enriches the aroma layers. (4) The final product contains high levels of five core active ingredients: verbascoside, paeoniflorin, total flavonoids, polysaccharides, and ferulic acid, which significantly improve sleep quality and skin condition, achieving the effect of "internal nourishment and external protection". (5) The process has good repeatability and good stability in large-scale production. Detailed Implementation
[0016] In this invention, the raw materials include wheat flour with a fineness ≥80 mesh and a protein content ≥13.0%; Polygonatum sibiricum is processed with wine and has a polysaccharide content ≥12%; Rehmannia glutinosa is prepared by nine steaming and nine drying processes, using Rehmannia glutinosa from Huaiqing, Henan; roses are double-petaled red roses from Pingyin, Shandong; ginseng is five-year-old ginseng from Changbai Mountain, Jilin; Angelica sinensis is sulfur-free Angelica sinensis from Gansu and has a ferulic acid content ≥0.06%; gardenia contains geniposide ≥3.8%; jujubes are from the Yellow River beach and have a polysaccharide content ≥7%; active dry yeast for wine is EC1118 yeast; and rice is Osmanthus ball rice.
[0017] Example 1: 1. A beauty-enhancing and sleep-aiding herbal liqueur, comprising the following raw materials in parts by weight: 100 parts rice, 20 parts first herbal composition, and 117 parts second herbal composition; also comprising a compound medicinal starter, wherein the mass of the compound medicinal starter is 0.3% of the mass of the rice; The first herbal composition consists of the following raw materials in parts by weight: 5 parts Polygonatum sibiricum, 3 parts Rehmannia glutinosa, 3 parts Dioscorea opposita, 2 parts Cornus officinalis, 3 parts Poria cocos, 2 parts Lycium barbarum, 1.5 parts Ziziphus jujuba var. spinosa, 2 parts Ziziphus jujuba, and 2 parts Morus alba leaves; The second herbal composition consists of the following raw materials in parts by weight: 30 parts Rehmannia glutinosa, 20 parts Cornus officinalis, 10 parts Polygonatum odoratum, 10 parts Polygonatum sibiricum, 10 parts Rosa rugosa, 7 parts Angelica sinensis, 6 parts longan pulp, 3 parts dried tangerine peel, 3 parts Amomum villosum, 4 parts ginseng, 4 parts Astragalus membranaceus, 3 parts Eucommia ulmoides leaf, 4 parts Lycium barbarum, and 3 parts Euryale ferox. The compound medicinal starter comprises the following raw materials: wheat flour, core active ingredient, traditional auxiliary ingredients, active medicinal materials, and Polygonum hydropiper activator; the core active ingredient, traditional auxiliary ingredients, active medicinal materials, and Polygonum hydropiper activator account for 2.8%, 1.2%, 2.6%, and 35% of the mass content of the wheat flour, respectively. The core active ingredient is composed of the following raw materials in parts by weight: 80 parts Angelica sinensis, 70 parts Gardenia jasminoides, 70 parts Salvia miltiorrhiza, and 60 parts Ligusticum chuanxiong. The traditional auxiliary medicine is composed of the following raw materials in parts by weight: Astragalus membranaceus 20 parts, Eucommia ulmoides leaves 20 parts, Glycyrrhiza uralensis 20 parts, Poria cocos 20 parts, Atractylodes macrocephala 20 parts, and Codonopsis pilosula 20 parts. The medicinal materials with efficacy are composed of the following ingredients in parts by weight: 50 parts Polygonatum sibiricum, 50 parts jujube, 40 parts wolfberry, 30 parts longan pulp, 30 parts yam, 30 parts hawthorn, 20 parts mulberry, and 10 parts kudzu root. The *Polygonum hydropiper* activator was prepared by the following method: *Polygonum hydropiper* from Xiecun, Shaanxi Province, collected in early September of the lunar calendar, was decocted with 10 times its volume of water for 1.5 hours, filtered, and the resulting filtrate was the *Polygonum hydropiper* activator, with a viable bacterial count ≥ 1 × 10⁻⁶. 6 CFU / mL; 2. The preparation method of the beauty-enhancing and sleep-aiding herbal liqueur includes the following steps: (a) Preparation of compound medicinal starter: (1) Raw material preparation: slice Angelica sinensis to a thickness of 2-2.5 mm, crush raw materials other than Angelica sinensis, traditional auxiliary drugs and functional medicinal materials in the core main drug, and then mix them with the sliced Angelica sinensis to obtain a mixture of Chinese medicinal materials for medicinal fermentation; (2) Mixing and molding: The wheat flour, the medicinal herb mixture, and the Polygonum hydropiper activator were mixed and stirred for 11 minutes. The mixture was then pressed at 0.8 MPa to obtain koji blocks with a density of 1.25 ± 0.01 g / cm³. 2 ; (3) Gradient aging: The koji blocks are first aged in an environment with a temperature of 19±1℃ and a relative humidity of 60±2% for 3 days, then in an environment with a temperature of 17±1℃ and a relative humidity of 58±2% for 4 days, then in an environment with a temperature of 15±1℃ and a relative humidity of 55±2% for 4 days, reducing the moisture content to 13.0±0.3%, and finally aged for 50 days at a temperature of 16±1℃ and a relative humidity of 55±2%. During the aging period, the blocks are turned over regularly, crushed to 50 mesh, vacuum-packed, and stored at 15℃. (II) Preparation of base liquor: Mix rice and the first herbal composition, steam for 45 minutes, cool to room temperature, add the compound medicinal yeast described in Example 1, mix and stir evenly, add purified water to adjust the total water content to 58%, ferment at 19±0.5℃ for 40 days, then ferment at 16±1℃ for 45 days, press, clarify, remove sediment to obtain base liquor; (III) Preparation of the efficacy extract: Rehmannia glutinosa, Cornus officinalis, Polygonatum odoratum, Polygonatum sibiricum, Angelica sinensis, longan pulp, ginseng, Astragalus membranaceus, Eucommia ulmoides leaf, and Euryale ferox were divided into group A. Group A was extracted with water as follows: 10 times the mass of water was added to the raw materials of group A, and ultrasonic extraction was performed at 85℃ and 1000W for 45 minutes. The ultrasonic extraction was repeated twice. The extract was filtered, and the filtrate was concentrated to a relative density of 1.10 to obtain the extract. The relative density mentioned in this invention is the ratio of the density of the filtrate to the density of water at 50℃ under the same temperature and pressure, which is the relative density (specific gravity). Rose petals, dried tangerine peel, cardamom, and wolfberry were divided into group B. Group B was extracted with alcohol as follows: 8 times the amount of 60% ethanol was added to the raw materials of group B, and ultrasonic extraction was performed at 800W and 60℃ for 40 minutes. The ultrasonic extraction was repeated twice, and the ethanol was recovered to obtain the extract. The extract obtained by water extraction and the extract obtained by alcohol extraction are mixed and diluted with purified water to 0.1 times the volume of the base wine to obtain the efficacy extract. (iv) Secondary fermentation: The base wine is mixed with the efficacy extract, and active dry yeast for wine is added at a dosage of 150 mg / L. Fermentation is carried out at 18±0.5℃ for 20 days. (V) Post-processing: pasteurize at 65℃ for 30 min, centrifuge at 10000 r / min for 10 min, add clarifying agent bentonite at 0.1 wt%, let stand for 7 days, age the supernatant in earthenware jars at 15±0.5℃ for 4 months, filter through a 0.45 μm membrane, and aseptically fill.
[0018] Example 2: In the preparation method, purified water is used to adjust the volume to 0.05 times that of the base wine, and the rest is the same as in Example 1.
[0019] Example 3: 1. A beauty-enhancing and sleep-aiding herbal liqueur, comprising the following raw materials in parts by weight: 100 parts rice, 15 parts first herbal composition, and 98 parts second herbal composition; also comprising a compound koji, wherein the mass of the compound koji is 0.28% of the mass of the rice; The first herbal composition consists of the following raw materials in parts by weight: 4 parts Polygonatum sibiricum, 2 parts Rehmannia glutinosa, 2 parts Dioscorea opposita, 1 part Cornus officinalis, 2 parts Poria cocos, 1 part Lycium barbarum, 1 part Ziziphus jujuba var. spinosa, 1 part Ziziphus jujuba, and 1 part Morus alba leaf. The second herbal composition consists of the following raw materials in parts by weight: 28 parts Rehmannia glutinosa, 18 parts Cornus officinalis, 8 parts Polygonatum odoratum, 8 parts Polygonatum sibiricum, 8 parts Rosa rugosa, 6 parts Angelica sinensis, 5 parts longan pulp, 2 parts dried tangerine peel, 2 parts Amomum villosum, 3 parts ginseng, 3 parts Astragalus membranaceus, 2 parts Eucommia ulmoides leaf, 3 parts Lycium barbarum, and 2 parts Euryale ferox. The compound medicinal starter comprises the following raw materials: wheat flour, core active ingredient, traditional auxiliary ingredients, active medicinal materials, and Polygonum hydropiper activator; the core active ingredient, traditional auxiliary ingredients, active medicinal materials, and Polygonum hydropiper activator account for 2.3%, 1.1%, 2.2%, and 30% of the mass content of the wheat flour, respectively. The core active ingredient is composed of the following raw materials in parts by weight: Angelica sinensis 60 parts, Gardenia jasminoides 60 parts, Salvia miltiorrhiza 60 parts, and Ligusticum chuanxiong 50 parts; The traditional auxiliary medicine is composed of the following raw materials in parts by weight: Astragalus membranaceus 15 parts, Eucommia ulmoides leaves 15 parts, Glycyrrhiza uralensis 20 parts, Poria cocos 20 parts, Atractylodes macrocephala 20 parts, and Codonopsis pilosula 20 parts. The medicinal materials with efficacy are composed of the following ingredients in parts by weight: 45 parts Polygonatum sibiricum, 40 parts jujube, 40 parts wolfberry, 25 parts longan pulp, 25 parts yam, 25 parts hawthorn, 15 parts mulberry, and 5 parts kudzu root. The red knotweed activator is prepared by the following method: Red knotweed from Xiecun, Shaanxi Province, collected in early September of the lunar calendar, is decocted with 8 times the amount of water for 1 hour, filtered, and the resulting filtrate is the red knotweed activator. 2. The preparation method of the beauty-enhancing and sleep-aiding herbal liqueur includes the following steps: (a) Preparation of compound medicinal starter: (1) Raw material preparation: slice Angelica sinensis to a thickness of 2-2.5 mm, crush raw materials other than Angelica sinensis, traditional auxiliary drugs and functional medicinal materials in the core main drug, and then mix them with the sliced Angelica sinensis to obtain a mixture of Chinese medicinal materials for medicinal fermentation; (2) Mixing and molding: The wheat flour, the medicinal herb mixture, and the Polygonum hydropiper activator were mixed and stirred for 11 minutes. The mixture was then pressed at 0.8 MPa to obtain koji blocks with a density of 1.1 ± 0.01 g / cm³. 2 ; (3) Gradient aging: The koji blocks are first aged in an environment with a temperature of 19±1℃ and a relative humidity of 60±2% for 5 days, then in an environment with a temperature of 17±1℃ and a relative humidity of 58±2% for 3 days, then in an environment with a temperature of 15±1℃ and a relative humidity of 55±2% for 5 days, and finally aged in an environment with a temperature of 16±1℃ and a relative humidity of 55±2% for 50 days. During the aging period, the blocks are turned over regularly, crushed to 50 mesh, vacuum packaged, and stored at 15℃. (II) Preparation of base liquor: Mix rice and the first herbal composition, steam for 40 minutes, cool to room temperature, add the compound medicinal yeast described in Example 1, mix and stir evenly, add purified water to adjust the total water content to 56%, ferment at 18±0.5℃ for 45 days, then ferment at 15±1℃ for 40 days, press, clarify, remove sediment to obtain base liquor; (III) Preparation of efficacy extract: Rehmannia glutinosa, Cornus officinalis, Polygonatum odoratum, Polygonatum sibiricum, Angelica sinensis, longan pulp, ginseng, Astragalus membranaceus, Eucommia ulmoides leaf, and Euryale ferox were divided into group A; group A was extracted with water as follows: 8 times the mass of water was added to the raw materials of group A, and ultrasonic extraction was performed at 1000W and 80℃ for 40 minutes. The ultrasonic extraction was repeated twice. The extract was filtered, and the filtrate was concentrated to a relative density of 1.10 to obtain the extract. Rose petals, dried tangerine peel, cardamom, and wolfberry were divided into group B. Group B was extracted with alcohol as follows: 10 times the amount of 60% ethanol was added to the raw materials of group B, and ultrasonic extraction was performed at 800W and 65℃ for 45 minutes. The ultrasonic extraction was repeated twice, and the ethanol was recovered to obtain the extract. The extract obtained by water extraction and the extract obtained by alcohol extraction are mixed and diluted with purified water to 0.08 times the volume of the base wine to obtain the efficacy extract. (iv) Secondary fermentation: The base wine is mixed with the efficacy extract, and active dry wine yeast is added at a dosage of 100 mg / L. Fermentation is carried out at 16 ± 0.5℃ for 30 days. (V) Post-processing: pasteurize at 65℃ for 30 min, centrifuge at 10000 r / min for 10 min, add clarifying agent bentonite at 0.05 wt%, let stand for 10 days, age the supernatant in earthenware jars at 16±0.5℃ for 4 months, filter through a 0.45 μm membrane, and aseptically fill.
[0020] Example 4: 1. A beauty-enhancing and sleep-aiding herbal liqueur, comprising the following raw materials in parts by weight: 100 parts rice, 32 parts first herbal composition, and 137 parts second herbal composition; also comprising a compound koji, wherein the mass of the compound koji is 0.32% of the mass of the rice; The first herbal composition consists of the following raw materials in parts by weight: 6 parts Polygonatum sibiricum, 4 parts Rehmannia glutinosa, 4 parts Dioscorea opposita, 3 parts Cornus officinalis, 4 parts Poria cocos, 3 parts Lycium barbarum, 2 parts Ziziphus jujuba var. spinosa, 3 parts Ziziphus jujuba, and 3 parts Morus alba leaves. The second herbal composition consists of the following raw materials in parts by weight: 32 parts Rehmannia glutinosa, 22 parts Cornus officinalis, 12 parts Polygonatum odoratum, 12 parts Polygonatum sibiricum, 12 parts Rosa rugosa, 9 parts Angelica sinensis, 7 parts longan pulp, 4 parts dried tangerine peel, 4 parts Amomum villosum, 5 parts ginseng, 5 parts Astragalus membranaceus, 4 parts Eucommia ulmoides leaf, 5 parts Lycium barbarum, and 4 parts Euryale ferox. The compound medicinal starter comprises the following raw materials: wheat flour, core active ingredient, traditional auxiliary ingredients, active medicinal materials, and Polygonum hydropiper activator; the core active ingredient, traditional auxiliary ingredients, active medicinal materials, and Polygonum hydropiper activator account for 3.2%, 1.4%, 3.1%, and 40% of the mass content of the wheat flour, respectively. The core active ingredient is composed of the following raw materials in parts by weight: Angelica sinensis 90 parts, Gardenia jasminoides 80 parts, Salvia miltiorrhiza 80 parts, and Ligusticum chuanxiong 70 parts; The traditional auxiliary medicine is composed of the following raw materials in parts by weight: Astragalus membranaceus 20 parts, Eucommia ulmoides leaves 20 parts, Glycyrrhiza uralensis 25 parts, Poria cocos 25 parts, Atractylodes macrocephala 25 parts, and Codonopsis pilosula 25 parts. The medicinal materials with efficacy are composed of the following ingredients in parts by weight: 55 parts Polygonatum sibiricum, 55 parts jujube, 55 parts wolfberry, 35 parts longan pulp, 35 parts yam, 35 parts hawthorn, 25 parts mulberry, and 15 parts kudzu root. The *Polygonum hydropiper* activator was prepared by the following method: *Polygonum hydropiper* from Xiecun, Shaanxi Province, collected in early September of the lunar calendar, was decocted with 10 times its volume of water for 1.5 hours, filtered, and the resulting filtrate was the *Polygonum hydropiper* activator, with a viable bacterial count ≥ 1 × 10⁻⁶. 6 CFU / mL; 2. The preparation method of the beauty-enhancing and sleep-aiding herbal liqueur includes the following steps: (a) Preparation of compound medicinal starter: (1) Raw material preparation: slice Angelica sinensis to a thickness of 2-2.5 mm, crush raw materials other than Angelica sinensis, traditional auxiliary drugs and functional medicinal materials in the core main drug, and then mix them with the sliced Angelica sinensis to obtain a mixture of Chinese medicinal materials for medicinal fermentation; (2) Mixing and molding: The wheat flour, the medicinal herb mixture, and the Polygonum hydropiper activator were mixed and stirred for 11 minutes. The mixture was then pressed at 0.8 MPa to obtain koji blocks with a density of 1.4 ± 0.01 g / cm³. 2 ; (3) Gradient aging: The koji blocks are first aged in an environment with a temperature of 19±1℃ and a relative humidity of 60±2% for 4 days, then in an environment with a temperature of 17±1℃ and a relative humidity of 58±2% for 5 days, then in an environment with a temperature of 15±1℃ and a relative humidity of 55±2% for 3 days, and finally aged in an environment with a temperature of 16±1℃ and a relative humidity of 55±2% for 50 days. During the aging period, the blocks are turned over regularly, crushed to 50 mesh, vacuum packaged, and stored at 15℃. (II) Preparation of base liquor: Mix rice and the first herbal composition, steam for 50 minutes, cool to room temperature, add the compound medicinal yeast described in Example 1, mix and stir evenly, add purified water to adjust the total water content to 60%, ferment at 20±0.5℃ for 42 days, then ferment at 17±1℃ for 42 days, press, clarify, remove sediment to obtain base liquor; (III) Preparation of efficacy extract: Rehmannia glutinosa, Cornus officinalis, Polygonatum odoratum, Polygonatum sibiricum, Angelica sinensis, longan pulp, ginseng, Astragalus membranaceus, Eucommia ulmoides leaf, and Euryale ferox were divided into group A; group A was extracted with water as follows: 10 times the mass of water was added to the raw materials of group A, and ultrasonic extraction was performed at 85℃ and 1000W for 40 minutes. The ultrasonic extraction was repeated twice. The mixture was filtered, and the filtrate was concentrated to a relative density of 1.10 to obtain the extract. Rose petals, dried tangerine peel, cardamom, and wolfberry were divided into group B. Group B was extracted with alcohol as follows: 8 times the amount of 60% ethanol was added to the raw materials of group B, and ultrasonic extraction was performed at 800W and 60℃ for 40 minutes. The ultrasonic extraction was repeated twice, and the ethanol was recovered to obtain the extract. The extract obtained by water extraction and the extract obtained by alcohol extraction are mixed and diluted with purified water to 0.1 times the volume of the base wine to obtain the efficacy extract. (iv) Secondary fermentation: Mix the base wine with the efficacy extract, add active dry yeast for wine at a dosage of 200 mg / L, and ferment at 22±0.5℃ for 10 days; (V) Post-processing: pasteurize at 65℃ for 30 min, centrifuge at 10000 r / min for 10 min, add clarifying agent bentonite at 0.15 wt%, let stand for 7 days, age the supernatant in earthenware jars at 16±0.5℃ for 4 months, filter through a 0.45 μm membrane, and aseptically fill.
[0021] Comparative Example 1: Wheat koji was used instead of compound medicinal koji in the raw materials, and everything else was the same as in Example 1; The preparation method uses a traditional soaking process, as detailed below: (1) Preparation of base wine: Steam rice for 45 minutes, cool it to room temperature, add wheat koji as a fermentation agent, mix and stir evenly, add purified water to adjust the total water content to 58%, ferment at 28℃±2℃ for 30 days, and obtain the base wine of yellow rice wine after pressing and clarification; the alcohol content of the base wine is about 12% vol, and there is no enrichment of directional functional components. (2) Soaking and extraction: The first herbal composition and the second herbal composition are mixed, dried and then pulverized through a 40-mesh sieve to obtain mixed herbal powder; the mixed herbal powder is added to the base wine at a mass ratio of 1:10, and the mixture is sealed and soaked at 25°C for 30 days, with stirring once every 3 days during the period. (3) Post-treatment: After soaking, the residue was removed by filtration using a plate and frame filter press. The supernatant was taken after the filtrate settled naturally for 24 hours. After pasteurization (65℃, 30min), it was filled to obtain the product of Comparative Example 1.
[0022] Comparative Example 2: Wheat koji was used instead of compound medicinal koji in the raw materials, and everything else was the same as in Example 1; It is prepared using a single fermentation process, as detailed below: (1) Fermentation process: Mix rice with the first herbal composition and the second herbal composition, add purified water, soak together for 2 hours, steam until cooked and cool, mix in wheat koji, stir evenly, add purified water to adjust the total moisture content to 58%, put into a vat for fermentation, control the fermentation temperature at 28±2℃, and the fermentation cycle is 30 days; there is no segmented temperature control design during the period, only turning once every 3 days; (2) Post-processing: After fermentation, the wine is pressed and filtered, and then naturally settled, pasteurized (65℃, 30min), and then bottled to obtain the product of Comparative Example 2.
[0023] Performance testing 1. Determination of the content of active ingredients To verify the technical effects of the present invention, the finished products prepared in Example 1 (10:1) and Example 2 (10:0.5) were systematically tested and evaluated, and compared with the comparative products prepared by the traditional process. Three batches were prepared for each test, and the average value was taken. The results are shown in Table 1. Table 1 Content of active ingredients
[0024] As shown in Table 1, the liqueur prepared by this invention has high contents of verbascoside, paeoniflorin, total flavonoids, polysaccharides, ferulic acid, etc. Comparative Example 1 uses a "one-pot" soaking process, with all medicinal materials added at once; it uses base liquor fermented with ordinary wheat koji, without functional directional design; the fermentation cycle is short (30 days), and the temperature control is rudimentary (constant temperature of 28℃); there is no segmented extraction or secondary fermentation; the active ingredients of the medicinal materials only undergo physical dissolution, lacking biotransformation. Comparative Example 2 adopted a "one-pot" mixed fermentation process; ordinary wheat koji was used, without any special medicinal koji design; the fermentation temperature was high (28℃) and the cycle was short (30 days), which was not conducive to the generation and accumulation of functional components such as ferulic acid; all medicinal materials were put into fermentation without distinguishing the stages and forms of different medicinal materials participating in fermentation; there was no segmented extraction process, and heat-sensitive and alcohol-soluble components were easily lost. By comparing two sets of traditional processes, the technical advantages of this invention in terms of extraction efficiency and biotransformation capability can be fully verified.
[0025] 2. Clinical observation of the product's sleep-aiding efficacy (1) Subjects: Sample size: A total of 400 subjects were recruited, including 200 subjects in the experimental group (product of Example 1 of this invention) and 200 subjects in the control group (placebo, which has similar appearance and taste but does not contain active ingredients). Gender and age distribution: Males: 182 (45.5%), aged 25-55 years, mean age 38.6 ± 8.2 years; Females: 218 cases (54.5%), aged 25-55 years, mean age 37.9 ± 8.5 years.
[0026] There were no statistically significant differences in gender and age distribution between the two groups (p>0.05); (2) Inclusion criteria Age 25-55, gender not limited; Meets the diagnostic criteria for mild to moderate sleep disorder: Pittsburgh Sleep Quality Index (PSQI) total score >5 and ≤15; I have not taken any sedative-hypnotic drugs, antidepressants, antihistamines, or health supplements in the past month; No serious heart, liver, kidney, nervous system diseases, or mental disorders; Voluntary participation and signing of informed consent form; The diagnostic criteria for insomnia are based on the World Health Organization (WHO) definition. (3) Exclusion criteria Shift workers or those who have recently traveled across time zones; Pregnant women, breastfeeding women, or women trying to conceive; Alcohol or drug dependents; Those allergic to any of the ingredients in the test product; Those currently participating in other clinical trials; (4) Test methods Trial period: 4 weeks of continuous intervention; Dosage and administration: The experimental group took 50 mL of the product of Example 1 of this invention orally one hour before bedtime daily; the control group took an equal amount of 50 mL of placebo, which had a similar appearance and taste. The placebo consisted of the following components: 14.74% edible alcohol by volume, 5.0 g / L citric acid, 0.2 g / L caramel color, and the remainder being purified water; the edible alcohol was 95% edible alcohol by volume. This placebo had an alcohol content of approximately 14% vol, an acidity of approximately 5 g / L, and an amber color. It was essentially identical to the product of Example 3 in appearance, taste, and alcohol content, but did not contain any herbal active ingredients. (5) Evaluation indicators The Pittsburgh Sleep Quality Index (PSQI) was used for pre- and post-assessment. The PSQI comprises seven components: subjective sleep quality, time to fall asleep, sleep duration, sleep efficiency, sleep disorders, use of hypnotics, and daytime dysfunction. Sleep efficiency calculation formula: Sleep efficiency (%) = (Actual sleep time / Bedtime) × 100%; Evaluation time points: before the trial (baseline), week 2 of the trial, and week 4 of the trial; References for PSQI scale and sleep efficiency calculation method: Buysse DJ, et al. Psychiatry Res, 1989; 28(2):193-213; (6) Test results Table 2 below shows the comparison of various indicators between the experimental group and the control group after 4 weeks of intervention; Table 2 Clinical observation results of sleep-aiding effects
[0027] Conclusion: The product of this invention can significantly shorten sleep latency, prolong sleep time, and improve sleep efficiency. The PSQI total score improvement rate reached 92.4%, the sleep latency was shortened from 45.6±8.3 min to 22.3±5.1 min, and the sleep efficiency was increased from 75.3±6.2% to 88.9±4.5%, demonstrating a clear effect on improving sleep.
[0028] 3. Clinical observation of the product's skin-nourishing effects (1) Subjects: Sample size: A total of 300 subjects were recruited, using a self-controlled before-and-after design; Age distribution: 30-55 years old, with an average age of 42.3 ± 6.8 years; among them, 108 cases (36.0%) were aged 30-39 years old, 132 cases (44.0%) were aged 40-49 years old, and 60 cases (20.0%) were aged 50-55 years old. Gender distribution: Males: 96 (32%), aged 30-55 years, mean age 42.3 ± 6.8 years; Females: 204 (68%), aged 30-55 years, mean age 41.9 ± 7.5 years; (2) Inclusion criteria for skin condition: Dry facial skin: Skin moisture content (Corneometer value) <50 au; Decreased skin elasticity: Skin elasticity index R2 < 0.65; Fine lines appear on the face (around the corners of the eyes, forehead, etc.); No serious skin diseases (such as eczema, psoriasis, active acne, etc.); (3) Exclusion criteria: I have received cosmetic treatments such as facial laser, chemical peels, or botulinum toxin injections within the past 3 months; Have used steroid creams or oral retinoids within the past month; Pregnant women and breastfeeding women; Those allergic to any of the ingredients in the test product; People with serious systemic diseases; The inclusion and exclusion criteria for subjects were based on the "Technical Specifications for Inspection and Evaluation of Health Foods" (2003 edition). (4) Test methods: Trial period: 8 consecutive weeks of intervention; Dosage and administration: Take 25 mL of the product of Example 3 of this invention orally after breakfast and dinner (total 50 mL / day), without the need for external skin care products; (5) Evaluation indicators and equipment: Skin moisture content: Measured on the cheek area using a Corneometer CM 825 (Courage+Khazaka, Germany). This device reflects moisture content by measuring changes in the capacitance of the stratum corneum; a higher value indicates higher moisture content. Skin elasticity: The cheek area was measured using a Cutometer MPA 580 (Courage+Khazaka, Germany). The main parameter was R2 (total elasticity), and the closer the value was to 1, the better the elasticity. Skin wrinkles: Facial images were acquired and analyzed using the VISIA-CR facial image analysis system (Canfield, USA) to quantitatively assess the depth and area of crow's feet wrinkles; Evaluation time points: before trial (baseline), week 4 of trial, and week 8 of trial; (6) Test results After 8 weeks of intervention, the changes in various skin indicators of 300 subjects are shown in Table 3 below; Table 3 Clinical observation of skin-nourishing effects
[0029] * p < 0.05 compared to baseline; ** p < 0.01 compared to baseline; (7) Subgroup analysis Stratified analysis by age group shows the skin hydration improvement effect of subjects in each age group as shown in Table 4 below; Table 4. Subgroup Analysis Results of Beauty-Enhancing Effects
[0030] The results showed that the product of this invention had significant skin moisturizing and elasticity-improving effects on subjects of different ages, with the most significant improvement in the 30-39 age group and significant improvement also observed in the 50-55 age group. (8) Subjective feelings and evaluation Eight weeks after the intervention, a standardized 5-point Likert scale was used to evaluate the subjects' subjective feelings. The scoring system was designed with reference to the human trial evaluation method for improving skin moisture function in the "Technical Specifications for Inspection and Evaluation of Health Foods" (2003 edition), and was combined with the internationally accepted Likert 5-point scale. ① Table 5. Five-level scoring standard system;
[0031] ② Description of the scoring anchor points for each evaluation indicator: To make the scoring criteria more operational, specific anchor point descriptions were set for each evaluation indicator, as shown in Table 6; Table 6. Description of scoring anchor points for each evaluation indicator
[0032] ③ Statistical method for scoring results: • Average score: The scores for each indicator are the mean ± standard deviation of the scores from 300 subjects; • Satisfaction rate: Satisfaction rate (%) = (Number of people who rated it 4 or 5 / Total number of people) × 100%; • Consistency test: Calculate inter-rater reliability, requiring Cronbach's α > 0.8; • Correlation analysis: Calculate the Pearson correlation coefficient between subjective scores and objective test indicators (Corneometer value, Cutometer R2 value, etc.); ④ The scoring results are shown in Table 7; Table 7 Scoring Results
[0033] ⑤ Consistency check of scoring • Cronbach's α coefficient: 0.86 (>0.8), indicating good internal consistency among raters; • Correlation between subjective ratings and objective test indicators: • Improvement rate of subjective skin hydration score vs. Corneometer value: r = 0.72 (p<0.01); • Improvement rate of subjective skin elasticity score vs. Cutometer R2: r = 0.68 (p<0.01); • Subjective score for fine line reduction vs. VISIA wrinkle depth reduction rate: r = 0.65 (p<0.01); The results showed that the subjects' subjective feelings were significantly positively correlated with the objective instrument test results, further verifying the skin-nourishing effects of the product of this invention. ⑥ Typical comments from test takers are summarized in Table 8; Table 8. Excerpt of typical testimonials from test takers
[0034] Conclusion: This product, administered orally, can significantly increase skin moisture content, improve skin elasticity, and reduce fine lines. After 8 weeks of intervention, skin moisture content increased by an average of 18.5%, skin elasticity improved by 16.8%, and the depth of crow's feet decreased by 13.7%. Subjective evaluation showed a skin hydration satisfaction rate of 94.3% and an overall satisfaction rate of 92.0%. Furthermore, subjective scores showed a significant positive correlation with objective test indicators, demonstrating clear beauty and skin-nourishing effects.
[0035] 4. Sensory evaluation of product flavor To scientifically evaluate the sensory quality of the product of this invention, a professional evaluation panel (10 evaluators) was organized to conduct a double-blind sensory evaluation, referring to the national standard GB / T 45172-2024 "Guidelines for Quantitative Description of Sensory Evaluation Panel Performance Evaluation" and relevant literature on food sensory evaluation methods. (1) Evaluation index system and scoring criteria Referring to the quantitative descriptive analysis (QDA) method and sensory evaluation system of rice wine reported in the literature, and combined with the product characteristics of the present invention, the evaluation index system shown in Table 9 below is established. Table 9 Evaluation Index System
[0036] (2) Scoring data processing: • Scoring calculation: The score for each indicator is the average of the scores from 10 evaluators ± standard deviation; • Total score calculation: A weighted comprehensive scoring method is used. Total score = Average aroma score × 30% + Average taste score × 40% + Average integration score × 30%; • Consistency test: Calculate the Cronbach's α coefficient among the tasters. A value greater than 0.8 indicates good consistency. • Significance analysis: One-way ANOVA was performed using SPSS 26.0 software. p < 0.05 was considered statistically significant. The sensory evaluation results are shown in Table 10. Table 10 Sensory Evaluation Results
[0037] It can be seen that the product of Example 1 has a fresh and easy-to-drink flavor, while the product of Example 2 has a rich and layered flavor, proving that the process of the present invention can flexibly adjust the flavor profile of the product.
[0038] This invention, through systematic innovation, constructs a complete and interconnected three-tiered technical chain, from the creation of special medicinal yeast, to the targeted fermentation of base liquor, and then to the secondary fermentation of the extract. It also creatively sets a key ratio range of 10:1 to 0.5 between base liquor and extract. This solution successfully solves the core problems of existing technologies, such as single efficacy, crude processes, and unstable quality. The resulting product has clearly quantified active ingredients, clinically proven dual efficacy, significantly improved flavor and quality, and a stable and controllable production process. This invention not only represents a specific method for preparing high-quality herbal liqueurs but also provides an innovative paradigm for the entire functional fermented food field of "deep integration of medicinal material functions and fermentation processes," possessing significant technological advancement, clear practicality, and broad industrialization prospects.
Claims
1. A beauty-enhancing and sleep-aiding herbal liqueur, characterized in that: The raw materials include the following parts by weight: 100 parts rice, 15-32 parts of the first herbal composition, and 98-137 parts of the second herbal composition; it also includes a compound medicinal starter, wherein the mass of the compound medicinal starter is 0.28-0.32% of the mass of the rice. The first herbal composition consists of the following raw materials in parts by weight: 4-6 parts Polygonatum sibiricum, 2-4 parts Rehmannia glutinosa, 2-4 parts Dioscorea opposita, 1-3 parts Cornus officinalis, 2-4 parts Poria cocos, 1-3 parts Lycium barbarum, 1-2 parts Ziziphus jujuba var. spinosa, 1-3 parts Ziziphus jujuba, and 1-3 parts Morus alba. The second herbal composition consists of the following raw materials in parts by weight: 28-32 parts Rehmannia glutinosa, 18-22 parts Cornus officinalis, 8-12 parts Polygonatum odoratum, 8-12 parts Rosa rugosa, 6-9 parts Angelica sinensis, 5-7 parts longan pulp, 2-4 parts dried tangerine peel, 2-4 parts Amomum villosum, 3-5 parts ginseng, 3-5 parts Astragalus membranaceus, 2-4 parts Eucommia ulmoides leaf, 3-5 parts Lycium barbarum, and 2-4 parts Euryale ferox.
2. The beauty-enhancing and sleep-aiding herbal liqueur according to claim 1, characterized in that: The compound medicinal starter comprises the following raw materials: wheat flour, core active ingredient, traditional auxiliary ingredients, active medicinal materials, and Polygonum hydropiper activator; the core active ingredient, traditional auxiliary ingredients, active medicinal materials, and Polygonum hydropiper activator account for 2.3-3.2%, 1.1-1.4%, 2.2-3.1%, and 30-40% of the mass content of the wheat flour, respectively. The core active ingredient is composed of the following raw materials in parts by weight: Angelica sinensis 60-90 parts, Gardenia jasminoides 60-80 parts, Salvia miltiorrhiza 60-80 parts, and Ligusticum chuanxiong 50-70 parts; The traditional adjuvant is composed of the following raw materials in parts by weight: Astragalus membranaceus 15-20 parts, Eucommia ulmoides leaves 15-20 parts, Glycyrrhiza uralensis 20-25 parts, Poria cocos 20-25 parts, Atractylodes macrocephala 20-25 parts, and Codonopsis pilosula 20-25 parts. The medicinal materials with efficacy are composed of the following raw materials in parts by weight: 45-55 parts of Polygonatum sibiricum, 40-55 parts of jujube, 40-55 parts of wolfberry, 25-35 parts of longan pulp, 25-35 parts of yam, 25-35 parts of hawthorn, 15-25 parts of mulberry, and 5-15 parts of kudzu root. The red knotweed activator is prepared by the following method: add 8-12 times the amount of water to the whole red knotweed herb, decoct for 1-2 hours, filter, and the resulting filtrate is the red knotweed activator.
3. The preparation method of the beauty-enhancing and sleep-aiding herbal liqueur according to claim 2, characterized in that: Includes the following steps: (a) Preparation of compound medicinal starter; (II) Preparation of base liquor: Mix rice and the first herbal composition, steam for 40-50 minutes, cool to room temperature, add the compound medicinal yeast, mix and stir evenly, add purified water to adjust the total water content to 56-60%, ferment at (18-20) ±0.5℃ for 40-45 days, then ferment at (15-17) ±1℃ for 40-45 days, press, clarify, remove sediment to obtain base liquor; (III) Preparation of efficacy extract: The different raw materials in the second herbal composition are divided into two groups, and water extraction and alcohol extraction are used for group extraction respectively. The extract obtained by water extraction is mixed with the extract obtained by alcohol extraction, and the volume is adjusted with purified water to 0.05-0.1 times the volume of the base wine to obtain efficacy extract; (iv) Secondary fermentation: Mix the base wine with the efficacy extract, add active dry yeast for wine, and ferment at (16-22)±0.5℃ for 10-30 days; (v) Post-processing: Sterilize, centrifuge, add clarifying agent, stand for 7-10 days, age the supernatant at (15-16)±0.5℃ for 4 months, filter finely, and aseptically fill.
4. The preparation method of the beauty-enhancing and sleep-aiding herbal liqueur according to claim 3, characterized in that: The preparation of the compound medicinal formula includes the following steps: (1) Raw material preparation: slice Angelica sinensis, crush raw materials other than Angelica sinensis, traditional auxiliary drugs and functional medicinal materials in the core main drug, and then mix them with sliced Angelica sinensis to obtain a mixture of Chinese medicinal materials for medicinal fermentation; (2) Mixing and molding: Mix the wheat flour, medicinal koji, and red knotweed activator, stir, press and mold to obtain koji blocks; (3) Gradual drying: The koji blocks are dried in an environment where the temperature and relative humidity decrease in sequence. Finally, they are aged for no less than 40 days at a temperature of 16±1℃ and a relative humidity of 55±2%. During the aging period, they are turned over, crushed, and vacuum packaged.
5. The preparation method of the beauty-enhancing and sleep-aiding herbal liqueur according to claim 4, characterized in that: In step (3), the gradient drying process is as follows: the gluten blocks are first dried and aged in an environment with a temperature of 19±1℃ and a relative humidity of 60±2% for 3-5 days, then dried in an environment with a temperature of 17±1℃ and a relative humidity of 58±2% for 3-5 days, and then dried in an environment with a temperature of 15±1℃ and a relative humidity of 55±2% for 3-5 days.
6. The method for preparing the beauty-enhancing and sleep-aiding herbal liqueur according to claim 4, characterized in that: In step (2), the density of the curved block is (1.1-1.4) ± 0.01 g / cm³. 2 .
7. The method for preparing the beauty-enhancing and sleep-aiding herbal liqueur according to claim 3, characterized in that: In step (ii), when fermenting at (18-20)±0.5℃, stir once every 5-6 days; when fermenting at (15-17)±1℃, stir once every 9-10 days.
8. The method for preparing the beauty-enhancing and sleep-aiding herbal liqueur according to claim 3, characterized in that: In step (3), the raw materials are grouped and extracted as follows: Rehmannia glutinosa, Cornus officinalis, Polygonatum odoratum, Polygonatum sibiricum, Angelica sinensis, longan pulp, ginseng, Astragalus membranaceus, Eucommia ulmoides leaves, and Euryale ferox are divided into group A; Rose, Citrus reticulata peel, Amomum villosum, and Lycium barbarum are divided into group B; group A is extracted with water, and group B is extracted with alcohol.
9. The method for preparing the beauty-enhancing and sleep-aiding herbal liqueur according to claim 8, characterized in that: The water extraction is as follows: add 8-10 times the mass of water to the raw materials in group A, and extract ultrasonically at 80-85℃ for 40-45 minutes. Repeat the ultrasonic extraction twice. Filter, concentrate the filtrate, and obtain the extract. The alcohol extraction is as follows: add 8-10 times the mass of ethanol to the raw materials in group B, and extract ultrasonically at 60-65℃ for 40-45 minutes. Repeat the ultrasonic extraction twice. Recover the ethanol to obtain the extract.
10. The method for preparing the beauty-enhancing and sleep-aiding herbal liqueur according to claim 3, characterized in that: The amount of active dry yeast added to the wine is 100-200 mg / L; the clarifying agent is bentonite, and the amount of the clarifying agent added accounts for 0.05-0.15% of the mass of the substance to be clarified.