Preparation process of high-absorption radix rehmanniae preparata by nine-steaming and nine-drying
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 丁雨思
- Filing Date
- 2026-06-30
- Publication Date
- 2026-08-07
AI Technical Summary
[0003]现有九蒸九晒工艺在实际生产中仍存在一定不足：一方面，传统蒸晒过程较依赖人工经验，原料回润程度、蒸制深度和晒制终点不易稳定控制，容易造成物料外熟内生、内外含水分布不均；另一方面，熟地黄经多次蒸晒后易出现黏腻、结块、外硬内湿等情况，影响后续切制、粉碎、煎煮和制剂加工
[0023]（1）本发明在九蒸九晒前设置浸润助渗步骤，并优选配合抽真空助渗处理，有利于提高浸润液进入原料内部的均匀性，改善传统熟地黄炮制中回润不均、内外受热不一致的问题。
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Figure CN122516280A_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of traditional Chinese medicine decoction piece processing technology, specifically referring to a nine-steaming and nine-drying preparation process for highly absorbable Rehmannia glutinosa. Background Technology
[0002] Prepared Rehmannia glutinosa is a commonly used traditional Chinese medicine decoction obtained by steaming, sun-drying, or drying Rehmannia glutinosa. It is widely used in preparations such as decoctions, pastes, pills, powders, and granules. Nine steaming and nine sun-drying is a classic processing method for prepared Rehmannia glutinosa. Through repeated steaming and sun-drying, the Rehmannia glutinosa is transformed from raw to cooked, causing corresponding changes in the color, texture, and internal components of the medicinal material.
[0003] The existing nine-steaming and nine-drying process still has certain shortcomings in actual production: On the one hand, the traditional steaming and drying process relies heavily on manual experience, and it is not easy to stably control the degree of raw material rehydration, steaming depth, and drying endpoint, which can easily lead to uneven moisture distribution and an unripe interior. On the other hand, after repeated steaming and drying, Rehmannia glutinosa is prone to becoming sticky, clumpy, hard on the outside and wet on the inside, affecting subsequent cutting, crushing, decoction, and preparation processing. For Rehmannia glutinosa that is further used in the form of raw materials for medicinal slices, pastes, pills, powders, or granules, there is still room for improvement in how to maintain the characteristics of the traditional nine-steaming and nine-drying process while improving the uniformity of soaking, the uniformity of heating, and the adaptability to subsequent processing.
[0004] Therefore, it is necessary to provide an improved preparation process for Rehmannia glutinosa using the nine-steaming and nine-drying method. Through measures such as soaking to enhance penetration, segmented steaming, sun drying or low-temperature drying, and final aging, the internal and external state of Rehmannia glutinosa during the processing can be made more consistent, and its subsequent preparation processing and performance can be improved. Summary of the Invention
[0005] In view of the above situation and to overcome the defects of the prior art, the present invention provides a nine-steaming and nine-drying preparation process for highly absorbent Rehmannia glutinosa. This process introduces a wetting and penetration aid treatment on the basis of the traditional nine-steaming and nine-drying process, and preferably combines vacuum penetration aid, segmented steaming and drying or low-temperature drying control to improve the wetting uniformity, heating uniformity and material stability during the processing of Rehmannia glutinosa.
[0006] The technical solution adopted in this invention is as follows: This invention proposes a nine-steaming and nine-drying preparation process for highly absorbent Rehmannia glutinosa, including the following steps:
[0007] S1. Raw material pretreatment: Take fresh Rehmannia glutinosa or raw Rehmannia glutinosa slices, remove mud and impurities, wash and cut into sections, blocks or slices to obtain pretreated raw materials.
[0008] S2. Impregnation and penetration aid: Mix the pretreated raw material with the impregnation liquid, allowing the impregnation liquid to penetrate into the pretreated raw material, and let it stand for 1-4 hours to rehydrate, thus obtaining the impregnated material.
[0009] S3. First steaming: Place the impregnated material in a steaming container and steam at 95-110℃ for 2-5 hours until the cut surface has no raw core and the material can be bent at 90° without breaking, thus obtaining the first steamed material.
[0010] S4. First sun-drying or low-temperature drying: The material that was first steamed is sun-dried or dried at low temperature until the surface of the material does not have obvious adhesion when pressed with a gloved finger and the material does not break when bent at 90°. This is the first sun-dried material.
[0011] S5. Repeated steaming and sun-drying: The material that was first sun-dried is repeatedly steamed and sun-dried or dried at low temperature, so that the total number of steaming is nine times and the total number of sun-drying or low-temperature drying is nine times, to obtain the nine-steamed and nine-sun-dried Rehmannia glutinosa semi-finished product.
[0012] S6. Final aging and finishing: The prepared Rehmannia glutinosa semi-finished product, which has been steamed and sun-dried nine times, is left to stand for aging for 24-72 hours. Then, it is dried at a low temperature of 35-55℃ until the moisture content is 12%-20%. After that, it is cut, shaped or packaged to obtain the finished Rehmannia glutinosa product.
[0013] Furthermore, the fresh Rehmannia root mentioned in step S1 is the fresh tuberous root of Rehmannia glutinosa, a plant of the Scrophulariaceae family, and the raw Rehmannia slices are the medicinal slices obtained by washing, cutting and drying fresh Rehmannia glutinosa.
[0014] Furthermore, the wetting solution mentioned in step S2 includes two or more of the following: rice wine, ginger juice, refined honey, and purified water. The wetting solution is used to pre-wet the raw materials before steaming, softening the material's structure and improving its internal and external consistency during subsequent steaming.
[0015] Furthermore, the soaking solution comprises, by weight, 50-80 parts rice wine, 5-20 parts ginger juice, 5-15 parts refined honey, and 10-30 parts purified water.
[0016] Further, the amount of wetting solution used in step S2 is 15%-30% of the weight of the pretreated raw material. The wetting aid includes vacuum-assisted penetration treatment, wherein the vacuum gauge pressure of the vacuum-assisted penetration treatment is -0.04MPa to -0.08MPa, and the treatment time is 10-30 minutes. Vacuum-assisted penetration treatment helps to promote the penetration of the wetting solution into the interior of the raw material, reducing the problem of inconsistent internal and external wetting during subsequent steaming.
[0017] Furthermore, the absence of a raw core in step S3 means that after cutting along the thickness direction of the material, the cut surface has a continuous color and no white core or light-colored hard core. The statement that the material can be bent 90° without breaking means that when a sheet of material with a thickness of 0.8-1.5cm or a slice of equal thickness is bent to 90°, there is no through-break.
[0018] Furthermore, in step S5, before the second to ninth steaming, a wetting solution is added, with the amount added being 3%-8% of the weight of the material to be steamed, and the steaming time for each steaming session being 1.5-4 hours. By adding the wetting solution before subsequent steaming sessions, it is beneficial to maintain the material's moist state and avoid excessive water loss after multiple sun-drying or drying processes.
[0019] Furthermore, the sun-drying or low-temperature drying in steps S4 and S5 is carried out at 25-60℃, and after each sun-drying or low-temperature drying, the surface of the material shows no obvious adhesion when pressed with a gloved finger, and the material does not break when bent at 90°. The final product of prepared Rehmannia glutinosa has a moisture content of 12%-20%.
[0020] The present invention also provides a highly absorbable Rehmannia glutinosa, which is prepared by the above-mentioned nine-steaming and nine-drying process of highly absorbable Rehmannia glutinosa; the water content of the highly absorbable Rehmannia glutinosa is 12%-20%, the water extract is not less than 40%, the Rehmannia glutinosa polysaccharide is not less than 7%, and the color difference ΔE of the cut surface is not higher than 3.0.
[0021] The present invention also provides the application of the above-mentioned Rehmannia glutinosa in the preparation of Rehmannia glutinosa slices, Rehmannia glutinosa paste raw materials, pill raw materials, powder raw materials or granule raw materials.
[0022] The beneficial effects achieved by this invention are as follows:
[0023] (1) The present invention sets up a soaking and penetration aiding step before nine steaming and nine sun drying, and preferably combines it with vacuum penetration aiding treatment, which is conducive to improving the uniformity of the soaking liquid entering the interior of the raw material and improving the problems of uneven moistening and inconsistent internal and external heating in the traditional processing of Rehmannia glutinosa.
[0024] (2) The present invention alternates between steaming and sun drying or low-temperature drying, and controls the material to remain moist and not scorched after each sun drying or low-temperature drying, which helps to reduce the situation of hard outside and wet inside, local scorching or sticking and clumping.
[0025] (3) The present invention adds soaking liquid before the second to ninth steaming, which helps to maintain the soft state of the material and improves the tissue softening and component release conditions of Rehmannia glutinosa during repeated steaming and drying.
[0026] (4) By limiting the amount of soaking liquid, the duration of rehydration, the steaming conditions, the drying conditions and the final aging time, the present invention makes it easier to control the moisture content and texture of the finished product. The resulting Rehmannia glutinosa is suitable for further preparation of raw materials for medicinal slices, pastes, pills, powders or granules, and has good adaptability to subsequent processing. Attached Figure Description
[0027] Figure 1 This is a flowchart of the nine-steaming and nine-drying process for preparing Rehmannia glutinosa according to the present invention;
[0028] The accompanying drawings are provided to further illustrate the invention and form part of the specification. They are used together with the embodiments of the invention to explain the invention and do not constitute a limitation thereof. Detailed Implementation
[0029] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative effort are within the scope of protection of the present invention.
[0030] Example 1: A nine-steaming and nine-drying preparation process for highly absorbable Rehmannia glutinosa, comprising the following steps:
[0031] S1. Raw material pretreatment: Take 100kg of fresh Rehmannia glutinosa, remove mud and sand and fibrous roots, wash it clean and cut it into pieces 3-5cm long and 0.8-1.5cm thick to obtain pretreated raw materials.
[0032] S2. Impregnation and Penetration Aid: Take 65 parts by weight of rice wine, 10 parts by weight of ginger juice, 10 parts by weight of refined honey, and 15 parts by weight of purified water, and mix them to form an impregnation solution. The amount of impregnation solution used is 22% of the weight of the pretreated raw materials. Spray the impregnation solution and mix it into the pretreated raw materials to evenly wet the surface of the raw materials. Then place the raw materials in a vacuum container and evacuate them at -0.06 MPa for 20 minutes. After that, let them stand for 2 hours to rehydrate and obtain the impregnated material.
[0033] S3. First steaming: Place the soaked material in a steamer, control the steaming temperature at 102℃, and steam for 3.5 hours until the raw material darkens in color, becomes soft to the touch, and has no raw center on the cut surface, thus obtaining the first steamed material.
[0034] S4. First sun-drying: Place the first steamed material in a clean sun-drying tray, control the surface temperature of the material and turn it over to sun-dry for 6-8 hours, until the surface of the material has no obvious adhesion when pressed with a gloved finger and the material does not break when bent at 90°, then the first sun-dried material is obtained.
[0035] S5. Repeated steaming and drying: Before the second to ninth steaming, add 5% of the weight of the material to be steamed with soaking liquid; the temperature of the second to fifth steaming is controlled at 100-105℃, and each steaming lasts for 2.5 hours; the temperature of the sixth to ninth steaming is controlled at 95-100℃, and each steaming lasts for 2 hours; after each steaming, the surface temperature of the material is controlled for drying, and each drying time is 5-8 hours. The material is dried until the surface of the material does not have obvious adhesion when pressed with a gloved finger and the material does not break when bent at 90°, until the nine steaming and nine drying are completed, and the nine-steamed and nine-dried Rehmannia glutinosa semi-finished product is obtained.
[0036] S6. Final aging and finishing: The semi-finished Rehmannia glutinosa that has been steamed and sun-dried nine times is placed in a clean container and aged for 48 hours. Then it is dried at a low temperature of 45℃ until the moisture content is 15%-18%. Then it is cut, shaped and packaged to obtain the finished Rehmannia glutinosa slices.
[0037] The prepared Rehmannia glutinosa slices obtained in this embodiment have a dark and lustrous color and a soft texture. After being cut, the color inside and outside is relatively consistent. They are not easy to stick to the knife when cutting, making them suitable for further preparation of medicinal slices or raw materials for ointments.
[0038] Example 2 A preparation process of Rehmannia glutinosa using nine steaming and nine sun-drying methods suitable for low-temperature drying conditions includes the following steps:
[0039] S1. Take 80kg of raw Rehmannia glutinosa slices as raw material, and set them aside after removing impurities by sieving.
[0040] S2. Take 70 parts by weight of rice wine, 8 parts by weight of ginger juice, 7 parts by weight of refined honey and 15 parts by weight of purified water, and mix them to form an impregnation solution; the amount of impregnation solution used is 18% of the weight of the raw Rehmannia glutinosa slices; spray the impregnation solution evenly onto the surface of the raw Rehmannia glutinosa slices and stir well, vacuum under -0.05MPa conditions for 15 minutes, and let it stand for 1.5 hours to rehydrate, and obtain the impregnation material.
[0041] S3. The impregnated material is steamed for the first time at a temperature of 98°C for 4 hours.
[0042] S4. Dry the material after the first steaming at a low temperature under hot air at 45℃ until the material is no longer sticky to the touch and does not break when bent, thus obtaining the first dried material.
[0043] S5. Then repeat the steaming and low-temperature drying steps to make the total number of steaming and low-temperature drying nine times. Before the second to ninth steaming, add soaking liquid, the amount of which is 4% of the weight of the material to be steamed. The temperature of each low-temperature drying is controlled at 40-50℃, and the material is dried until the surface is not sticky and the inside remains soft.
[0044] S6. Finally, age for 24 hours, then process at low temperature until the moisture content is 12%-16%, cut and shape to obtain the finished Rehmannia glutinosa product.
[0045] The prepared Rehmannia glutinosa product obtained in this embodiment has a non-sticky surface, remains soft inside, and has a moisture content controlled at 12%-16%, making it suitable for processing Rehmannia glutinosa under conditions where sun exposure is inconvenient.
[0046] Example 3: A preparation process of Rehmannia glutinosa using nine steaming and nine sun-drying without vacuum-assisted permeation, comprising the following steps:
[0047] S1. Take 120kg of fresh Rehmannia glutinosa, wash it and cut it into thick slices to obtain pre-treated raw materials.
[0048] S2. Take 55 parts by weight of rice wine, 15 parts by weight of ginger juice, 12 parts by weight of refined honey and 18 parts by weight of purified water, and mix them to form an impregnation solution; the amount of the impregnation solution is 25% of the weight of the pretreated raw materials; after mixing the pretreated raw materials with the impregnation solution, let it stand for 3 hours to rehydrate, and obtain the impregnated material.
[0049] S3. The impregnated material is steamed for the first time at a temperature of 105°C for 3 hours.
[0050] S4. After the first sun-drying, continue to repeat the steaming and sun-drying process. The sun-drying end point is when the surface of the material does not have obvious adhesion when pressed with a gloved finger and the material does not break when bent at 90°. Continue until the nine steaming and nine sun-drying processes are completed.
[0051] S5. After aging the prepared Rehmannia glutinosa (steamed and dried nine times) for 36 hours, shape it and adjust it until the moisture content is 16%-20% to obtain the finished prepared Rehmannia glutinosa.
[0052] This embodiment shows that the process of the present invention can be implemented without vacuum-assisted permeation treatment; when vacuum-assisted permeation treatment is used, it is generally more conducive to controlling the uniformity of wetting.
[0053] Comparative Example 1 uses the traditional method of steaming and drying Rehmannia glutinosa, without setting up a soaking and penetration aid step, and without adding soaking liquid before the second to ninth steaming. It is directly steamed and dried nine times after being moistened with regular rice wine.
[0054] Comparative Example 1, Rehmannia glutinosa sample, was obtained, and the test results are shown in Table 1.
[0055] Comparative Example 2 adopted the soaking solution treatment method of Example 1, but only steamed and dried three times before stopping, without performing the complete nine-steaming and nine-drying process.
[0056] Comparative Example 2, Rehmannia glutinosa sample, was obtained, and the test results are shown in Table 1.
[0057] Example 1: The prepared Rehmannia glutinosa samples obtained from Example 1, Comparative Example 1, and Comparative Example 2 were tested. Moisture content was determined by the loss on drying method; water extract was determined by the hot extraction method; Rehmannia glutinosa polysaccharides were determined by the phenol-sulfuric acid method; the color difference ΔE was the difference between the outer layer and the central area of the same sample measured by a colorimeter; the smaller the value, the better the consistency of color between the inner and outer layers; the cutting adhesion rate was the percentage of slices that stuck to the blade during continuous cutting out of the total number of slices; the fragmentation rate was the percentage of fragments that could not form complete medicinal slices after cutting out of the total cut mass. The test results are shown in Table 1.
[0058] Table 1. Detection results of Rehmannia glutinosa samples obtained by different steaming and drying processes.
[0059] sample Moisture content water leachate Rehmannia polysaccharide Cross-sectional color difference ΔE Cutting stickiness Fragmentation rate Example 1 16.2% 45.8% 8.6% 2.1 3.2% 4.5% Comparative Example 1 22.7% 38.4% 6.9% 7.8 12.6% 10.8% Comparative Example 2 18.5% 31.2% 5.1% 9.4 5.8% 13.5%
[0060] Table 1 shows that, compared with the traditional steam-drying control sample, the prepared Rehmannia glutinosa sample obtained in Example 1 had a moisture content controlled within a range suitable for cutting and storage, higher content of water extract and Rehmannia glutinosa polysaccharides, and lower color difference ΔE, cutting sticking rate, and fragmentation rate. These results indicate that the combination of soaking to aid penetration, adding soaking solution during the nine steaming and drying processes, and final aging in this invention is beneficial for improving the consistency of internal and external maturation of prepared Rehmannia glutinosa and its adaptability to subsequent cutting and processing. Compared with the incomplete steaming and drying control sample, the prepared Rehmannia glutinosa obtained in Example 1 had higher content of water extract and Rehmannia glutinosa polysaccharides, indicating that the complete nine-steaming and nine-drying process is conducive to the formation of conditions for the release of Rehmannia glutinosa components.
[0061] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A nine-steaming and nine-drying preparation process for highly absorbent Rehmannia glutinosa, characterized in that... Includes the following steps: S1. Raw material pretreatment: Take fresh Rehmannia glutinosa or raw Rehmannia glutinosa slices, remove mud and impurities, wash them and cut them into sections, chunks or slices to obtain pretreated raw materials; S2. Impregnation and penetration aid: Mix the pretreated raw material with the impregnation liquid, allowing the impregnation liquid to penetrate into the pretreated raw material, and let it stand for 1-4 hours to rehydrate, thus obtaining the impregnated material; S3. First steaming: Place the impregnated material in a steaming container and steam at 95-110℃ for 2-5 hours until the cut surface has no raw core and the material can be bent at 90° without breaking, thus obtaining the first steamed material; S4. First sun-drying or low-temperature drying: The first steamed material is sun-dried or dried at low temperature until the surface of the material does not have obvious adhesion when pressed with a gloved finger and the material does not break when bent at 90°, thus obtaining the first sun-dried material; S5. Repeated steaming and drying: The material that was dried in the first batch is repeatedly steamed and dried or dried at low temperature, so that the total number of steaming is nine times and the total number of drying or low temperature drying is nine times, to obtain the semi-finished product of Rehmannia glutinosa that has been steamed and dried nine times. S6. Final aging and finishing: The prepared Rehmannia glutinosa semi-finished product, which has been steamed and sun-dried nine times, is left to stand for aging for 24-72 hours. Then, it is dried at a low temperature of 35-55℃ until the moisture content is 12%-20%. After that, it is cut, shaped or packaged to obtain the finished Rehmannia glutinosa product.
2. The nine-steaming and nine-drying preparation process of highly absorbable Rehmannia glutinosa according to claim 1, characterized in that: The fresh Rehmannia root mentioned in step S1 is the fresh tuberous root of Rehmannia glutinosa, a plant of the Scrophulariaceae family, and the raw Rehmannia slices are the processed slices obtained by washing, cutting and drying fresh Rehmannia glutinosa.
3. The nine-steaming and nine-drying preparation process of highly absorbent Rehmannia glutinosa according to claim 1, characterized in that: The soaking solution mentioned in step S2 includes two or more of the following: rice wine, ginger juice, refined honey, and purified water.
4. The nine-steaming and nine-drying preparation process of highly absorbable Rehmannia glutinosa according to claim 1, characterized in that: The soaking solution comprises, by weight, 50-80 parts rice wine, 5-20 parts ginger juice, 5-15 parts refined honey, and 10-30 parts purified water.
5. The nine-steaming and nine-drying preparation process of highly absorbent Rehmannia glutinosa according to claim 1, characterized in that: The amount of the impregnation liquid used in step S2 is 15%-30% of the weight of the pretreated raw material. The impregnation aid includes vacuum aid treatment, where the vacuum gauge pressure of the vacuum aid treatment is -0.04MPa to -0.08MPa, and the treatment time is 10-30 minutes.
6. The nine-steaming and nine-drying preparation process of highly absorbable Rehmannia glutinosa according to claim 1, characterized in that: The "no raw core" mentioned in step S3 means that the cut surface has a continuous color and no white core or light-colored hard core after cutting along the thickness direction of the material.
7. The nine-steaming and nine-drying preparation process of highly absorbable Rehmannia glutinosa according to claim 1, characterized in that: In step S5, before the second to ninth steaming, a soaking liquid is added, with the amount added being 3%-8% of the weight of the material to be steamed, and the steaming time for each steaming is 1.5-4 hours.
8. The nine-steaming and nine-drying preparation process of highly absorbable Rehmannia glutinosa according to claim 1, characterized in that: The sun-drying or low-temperature drying in steps S4 and S5 is carried out at 25-60℃, and the material surface after each sun-drying or low-temperature drying has no obvious adhesion when pressed with a gloved finger, and the material does not break when bent at 90°.
9. A highly absorbable Rehmannia glutinosa, characterized in that, The highly absorbent Rehmannia glutinosa is prepared by the nine-steaming and nine-drying process of the highly absorbent Rehmannia glutinosa as described in any one of claims 1-8; the water content of the highly absorbent Rehmannia glutinosa is 12%-20%, the water extract is not less than 40%, the Rehmannia glutinosa polysaccharide is not less than 7%, and the color difference ΔE of the cut surface is not higher than 3.
0.
10. The use of the highly absorbent Rehmannia glutinosa as described in claim 9 in the preparation of Rehmannia glutinosa slices, Rehmannia glutinosa paste raw materials, pill raw materials, powder raw materials or granule raw materials.