Microsphere encapsulation apparatus

Abstract

The present application relates to a kind of microsphere packaging equipment, it includes: machine table and respectively on machine table test tube feeding mechanism, microsphere subpackaging mechanism, heat sealing mechanism and transfer mechanism.Test tube feeding station, microsphere subpackaging station and test tube sealing film station are equipped on machine table.Test tube feeding mechanism is configured to be able to batch feeding multiple test tubes to test tube feeding station.Microsphere subpackaging mechanism is configured to be able to simultaneously put microsphere to multiple test tubes located on microsphere subpackaging station.Heat sealing mechanism is configured to be able to simultaneously seal film to multiple test tubes located on test tube sealing film station.Transfer mechanism includes the transfer piece movable relative to machine table, and transfer piece is configured to be able to batch receive multiple test tubes that test tube feeding mechanism is fed to test tube feeding station, and transfer piece moves to make each test tube switch in turn between test tube feeding station, microsphere subpackaging station and test tube sealing film station.

Description

Technical Field

[0001] This invention relates to the field of microsphere packaging technology, and more specifically, to a microsphere packaging device. Background Technology

[0002] In the fields of in vitro diagnostics, pharmaceutical formulation, and biotechnology, it is often necessary to precisely and non-destructively dispense prepared microspheres into non-standard reaction containers and then perform heat sealing or capping. Currently, the industry's packaging methods are mainly divided into three categories: manual packaging, semi-automatic packaging, and fully automated packaging. Among them, fully automated packaging has significant advantages such as less human intervention and better packaging consistency, and therefore its application in industrial production is becoming increasingly widespread.

[0003] However, most fully automated packaging equipment currently on the market adopts a single-piece flow mode. This means that the container feeding mechanism can only process one reaction container at a time. Each reaction container then passes through the microsphere device and the packaging device, completing the steps of dispensing microspheres and packaging the reaction container, respectively, before finally being output. When large-scale mass production is required, this single-piece flow mode limits the number of reciprocating actions performed by each actuator (container feeding mechanism, microsphere device, and packaging device, etc.) equal to the number of test tubes. The number of actions increases linearly with production volume, leading to long production cycles and limited efficiency. Furthermore, the high-frequency repetitive actions of each actuator may accelerate cumulative wear, resulting in decreased accuracy and consistency after long-term operation, making it difficult to meet the stability requirements of large-scale mass production. Summary of the Invention

[0004] The purpose of this invention is to provide a microsphere encapsulation device to solve the problems mentioned in the background art.

[0005] To solve the above-mentioned technical problems, the present invention adopts the following technical solution.

[0006] This invention provides a microsphere encapsulation device, comprising: a machine base and a test tube feeding mechanism, a microsphere dispensing mechanism, a heat sealing mechanism, and a transfer mechanism respectively disposed on the machine base; the machine base is provided with a test tube feeding station, a microsphere dispensing station, and a test tube sealing station; the test tube feeding mechanism is configured to batch feed multiple test tubes to the test tube feeding station; the microsphere dispensing mechanism is configured to simultaneously dispense microspheres into multiple test tubes located at the microsphere dispensing station; the heat sealing mechanism is configured to simultaneously seal multiple test tubes located at the test tube sealing station; the transfer mechanism includes a transfer component movable relative to the machine base, the transfer component being configured to batch receive multiple test tubes fed to the test tube feeding station by the test tube feeding mechanism, and the transfer component being movable to allow each test tube to sequentially switch between the test tube feeding station, the microsphere dispensing station, and the test tube sealing station.

[0007] In some embodiments of this application, the transfer component is horizontally rotatable relative to the machine tool and has a horizontally arranged disc-shaped structure. A vertically penetrating clamping groove is formed on the outer edge of the transfer component. Multiple clamping grooves are arranged adjacent to each other along the circumference of the transfer component, forming a clamping groove group. Each clamping groove in the clamping groove group is configured to hold one test tube, or the clamping groove extends in one direction and is configured to hold multiple test tubes in batches, allowing the multiple test tubes to move along the designated path. The clamping grooves are arranged along their extension direction; the test tube loading station, microsphere dispensing station, and test tube sealing station are arranged horizontally and distributed circumferentially around the rotation center of the transfer component; the transfer component rotates horizontally to drive the clamping groove group to switch sequentially between the test tube loading station, microsphere dispensing station, and test tube sealing station, or the transfer component rotates horizontally to drive the clamping grooves extending in one direction to switch sequentially between the test tube loading station, microsphere dispensing station, and test tube sealing station.

[0008] In some embodiments of this application, a feeding station is provided on the horizontal side of the machine or on the machine. The feeding station is located on the same circumference as the test tube loading station, the microsphere dispensing station, and the test tube sealing station, and is located on the side of the test tube sealing station facing away from the microsphere dispensing station. The transfer mechanism also includes a bracket, a drive member, and a baffle located below the transfer member. The bracket has an inverted U-shaped structure and includes a first plate, a second plate, and a third plate connected in sequence. The first plate and the second plate are respectively connected to the machine. The drive member is located inside the bracket, and the output shaft of the drive member passes through the third plate and is connected to the transfer member. The baffle is provided on one of the first plate and the second plate. The baffle includes an outlet section located on the feeding station and is arranged inclined outward from the side closer to the test tube sealing station to the side farther away from the test tube sealing station.

[0009] In some embodiments of this application, the test tube loading mechanism includes a base, a material box, and a lifting seat; the base forms an inclined output channel, and the lower side of the output channel can dock with the clamping groove located at the test tube loading station; the material box is connected to the base and located on the horizontal side of the output channel, the material box has a funnel-shaped structure, the interior of the material box forms a material cavity capable of loading test tubes in batches, and the bottom of the material box has an opening communicating with the material cavity; the lifting seat is located below the material cavity, the top of the lifting seat has an upward-facing receiving groove, the receiving groove is inclined, and the lower side of the receiving groove forms an output end; the lifting seat is configured to be able to rise and fall relative to the base, and when the lifting seat rises relative to the base, it can gradually enter the material cavity through the opening, and allow several test tubes to be gradually inserted through the groove and arranged sequentially in the receiving groove, and the arranged test tubes can be sequentially output from the output end to the output channel when the lifting seat rises to a preset height.

[0010] In some embodiments of this application, the material box includes a housing and a guide plate and a baffle plate, both of which are oscillatingly connected to the housing; the housing has a hollow cylindrical structure and is vertically arranged on the base; the guide plate is arranged at an angle and together with the housing defines the material cavity, and an opening is left between the lower side of the guide plate and the housing, and the guide plate is configured to oscillate during the process of the lifting seat rising relative to the base; the baffle plate is disposed inside the housing, and the baffle plate is arranged vertically opposite to the guide plate and covers the opening.

[0011] In some embodiments of this application, the material box further includes rollers connected to the guide plate and located below the guide plate; the test tube feeding mechanism further includes a push plate connected to the lifting seat, and the lifting seat rises relative to the base, which can drive the push plate to contact and push the rollers upward, and cause the guide plate to swing.

[0012] In some embodiments of this application, the microsphere dispensing mechanism includes an upper ball seat, a lower ball seat, and a movable mechanism; the upper ball seat has at least two sets of channel groups inside, each channel group including a plurality of feeding channels; the lower ball seat has at least two discharge channels inside, each discharge channel being configured to dispense microspheres into multiple test tubes located at the microsphere dispensing station, the discharge channels being located below the channel groups and vertically offset from the channel groups; the movable mechanism includes a push plate, the push plate having at least two sets of groove groups, each groove group including a storage groove having the same number of feeding channels as the channel groups; The pusher plate is configured to reciprocate horizontally between the feed channel and the discharge channel, so that the storage tank has a receiving state and a releasing state; when the pusher plate moves to each feed channel of each of the channel groups and is vertically opposite to each storage tank of a tank group, the storage tank is in the receiving state, and each storage tank can receive a microsphere released by the corresponding feed channel; when the pusher plate moves to each storage tank of each tank group and is vertically opposite to a discharge channel, the storage tank is in the releasing state, and the microspheres in each storage tank enter the same discharge channel.

[0013] In some embodiments of this application, the pusher plate is movable relative to the upper ball seat along a first horizontal direction; each feed channel of the channel group and each storage tank of the trough group are arranged along a second horizontal direction perpendicular to the first horizontal direction; the pusher plate has a number of forming parts groups equal to the number of trough groups, each forming part group including multiple forming parts arranged sequentially in the second horizontal direction, each forming part having a storage tank, and in the second horizontal direction, the forming part group is in a stepped shape with the height of each forming part increasing or decreasing sequentially, so that the vertical distance between each storage tank of the same trough group and the feed port of the corresponding discharge channel is different, and the microspheres in each storage tank can sequentially enter the same discharge channel.

[0014] In some embodiments of this application, the discharge channel includes a main channel and a secondary channel that are connected to each other. The main channel extends vertically and forms a discharge port at its bottom end. The radial dimension of the main channel is configured to allow only a single microsphere to pass through. The secondary channel extends horizontally and is located above the main channel. The top end of the secondary channel forms the material passage. When the storage tank is in the release state, in the same tank group, the storage tank with the shortest vertical distance to the material passage is arranged vertically opposite to the main channel. The remaining storage tanks are arranged vertically opposite to the secondary channel. The secondary channel is configured to guide the microspheres released from the remaining storage tanks into the main channel in an orderly manner.

[0015] In some embodiments of this application, the heat-sealing mechanism includes a support base and a test tube holder, a cutting base, a heat-sealing and cutting assembly, and a film conveying assembly respectively disposed on the support base; the test tube holder is movable relative to the support base and is used to support multiple test tubes of the clamping groove group located on the test tube sealing station; the cutting base is located above the test tube holder and has multiple through holes corresponding to multiple test tubes respectively; the heat-sealing and cutting assembly is located above the cutting base and includes a cutting plate movable relative to the support base and a heat-sealing head disposed on the cutting plate, the heat-sealing head having multiple heat-sealing ends corresponding to multiple through holes respectively; the film conveying assembly is configured to convey film material between the heat-sealing head and the cutting base.

[0016] As can be seen from the above technical solutions, the embodiments of the present invention have at least the following advantages and positive effects: In the microsphere packaging equipment of this invention, the transport mechanism first receives multiple test tubes loaded by the test tube feeding mechanism at the test tube feeding station in batches. Then, it moves to the microsphere dispensing station, where the microsphere dispensing mechanism simultaneously dispenses microspheres into each test tube. After dispensing, the transport mechanism moves again, carrying the batch of microsphere-filled test tubes to the test tube sealing station, where the heat-sealing mechanism synchronously heat-seals the openings of each test tube. Finally, the transport mechanism removes the packaged batch of test tubes and outputs the finished product. Thus, by sequentially switching the transport mechanism between three fixed stations, and coordinating the batch synchronous operations of each mechanism at each station, efficient, stable, and continuous fully automated batch packaging of microspheres is achieved.

[0017] Specifically, the microsphere packaging equipment of this invention replaces the traditional "single-piece flow mode" with a "batch flow mode," reducing the frequency of operation of each actuator to 1 / N times (where N is the number of batches per batch) under the same output, thereby significantly shortening the batch production cycle and improving production efficiency. Simultaneously, due to the significant reduction in the frequency of operation of each actuator, the cumulative wear of mechanical transmission components is correspondingly reduced, which is beneficial for maintaining the operational accuracy and uniformity of each actuator over a long period, thus meeting the high-precision and high-stability production requirements of large-scale industrial mass production. Attached Figure Description

[0018] Various objects, features, and advantages of the invention will become more apparent from the following detailed description of preferred embodiments of the invention, taken in conjunction with the accompanying drawings. The drawings are merely illustrative of the invention and are not necessarily drawn to scale. In the drawings, the same reference numerals always denote the same or similar parts. Wherein: Figure 1 This is a schematic diagram of a microsphere encapsulation device according to an exemplary embodiment.

[0019] Figure 2 yes Figure 1 A top view of the intermediate machine platform and transfer mechanism.

[0020] Figure 3 yes Figure 1 A schematic diagram of the transshipment mechanism.

[0021] Figure 4 yes Figure 3 A schematic diagram of its decomposed structure.

[0022] Figure 5 yes Figure 1 A schematic diagram of the pilot tube feeding mechanism.

[0023] Figure 6 yes Figure 5 The diagram shows the structure of the test tube feeding mechanism from another perspective.

[0024] Figure 7 yes Figure 5 A schematic diagram of the structure of the intermediate material box.

[0025] Figure 8 yes Figure 7 A schematic diagram of its decomposed structure.

[0026] Figure 9 yes Figure 5 A schematic diagram of the working structure of the drive mechanism and the lifting seat.

[0027] Figure 10 for Figure 6 The diagram shows the structure of the test tube feeding mechanism after the shell is removed.

[0028] Figure 11 yes Figure 1 A schematic diagram of the microsphere dispensing mechanism.

[0029] Figure 12 yes Figure 1 A structural diagram in another state.

[0030] Figure 13 yes Figure 1 A schematic diagram of the structure after removing the material box.

[0031] Figure 14 yes Figure 13 A schematic diagram of its decomposed structure.

[0032] Figure 15 yes Figure 14 A schematic diagram of the exploded structure of the active mechanism.

[0033] Figure 16 yes Figure 11 A schematic diagram of the exploded structure of the lower ball seat.

[0034] Figure 17 yes Figure 1 A schematic diagram of the exploded structure of the upper ball seat.

[0035] Figure 18 yes Figure 12 A schematic diagram of the structure after removing the upper casing.

[0036] Figure 19 yes Figure 18 Top view of the lower middle box.

[0037] Figure 20 yes Figure 1 A schematic diagram of the heat sealing mechanism.

[0038] The annotations in the attached figures are explained as follows: 1. Machine base; 11. Test tube loading station; 12. Microsphere dispensing station; 13. Test tube sealing station; 14. Unloading station; 2. Test tube feeding mechanism; 21. Base; 211. Output channel; 22. Material box; 221. Shell; 2211. Upper shell; 22111. Inlet; 22112. Feed port; 2212. Lower shell; 22121. Support plate; 22122. Clearance opening; 222. Guide plate; 2221. Sub-plate; 22211. Extension plate; 223. Baffle plate; 2231. Main body; 2232. Baffle section 224. Roller; 225. Material cavity; 226. Opening; 227. Lifting channel; 23. Lifting seat; 231. Receiving groove; 2311. Groove opening; 2312. Output end; 232. Connecting hole; 24. Push plate; 25. Guide mechanism; 251. Slide rail; 252. Slide seat; 26. Drive mechanism; 261. Rotary drive component; 262. Lever; 2621. Strip hole; 263. Locking component; 3. Microsphere dispensing mechanism; 31. Upper ball seat; 311. Body; 3111. Guide groove; 3112. Feed groove; 3113. Air hole; 312. Cover; 3121. Displacement port; 313. Air passage connector; 314. Channel group; 3141. Feed channel; 32. Lower ball seat; 321. Discharge channel; 3211. Main channel; 32111. Discharge port; 3212. Secondary channel; 32121. Material passage port; 322. Blocking component; 33. Movable mechanism; 331. Push plate; 3311. Channel group; 33111. Material storage 3312, Groove; 33121, Forming part; 3313, Waist-shaped hole; 332, Cam; 333, Motor; 3331, Output shaft; 334, Support; 3341, Slide groove; 3342, First window; 335, Connecting cap; 3351, Positioning strip; 336, Position sensor; 34, Counting sensor; 35, Microsphere box; 351, Upper box; 3511, Cavity; 352, Lower box; 3521, Guide groove; 3522, Flow channel; 3523, First feed inlet; 3524, Second feed inlet; 4. Heat sealing mechanism; 41. Support base; 42. Test tube holder; 421. Base body; 422. Elastic element; 43. Cutting female base; 44. Heat sealing and cutting assembly; 441. Cutting plate; 442. Heat sealing head; 4421. Heat sealing end; 45. Film conveying assembly; 451. Unwinding shaft; 452. Rewinding shaft; 453. Drive roller; 454. Driven roller; 455. Pressing roller; 46. First lifting drive mechanism; 47. Second lifting drive mechanism; 5. Transfer mechanism; 51. Transfer component; 511. Clamping slot assembly; 5111. Clamping slot; 52. Limiting ring; 53. Bracket; 531. First plate; 532. Second plate; 533. Third plate; 54. Driving component; 55. Baffle; 551. Outgoing section; 552. Connecting section; 56. Position sensor; 57. Positioning piece; D1, first horizontal direction; D2, second horizontal direction. Detailed Implementation

[0039] Although the invention can be readily embodied in various forms, only some specific embodiments are shown in the accompanying drawings and will be described in detail in this specification. It is understood that this specification should be regarded as an exemplary illustration of the principles of the invention and is not intended to limit the invention to what is described herein.

[0040] Therefore, a feature pointed out in this specification is configured to illustrate one embodiment of the invention, rather than implying that every embodiment of the invention must have the described feature. Furthermore, it should be noted that this specification describes many features. While certain features may be combined to illustrate possible system designs, these features may also be configured to enable other combinations not explicitly stated. Therefore, unless otherwise stated, the described combinations are not intended to be limiting.

[0041] In the embodiments shown in the accompanying drawings, directional indications (such as up, down, left, right, front, and back) are configured to explain that the structure and movement of the various elements of the invention are relative rather than absolute. These descriptions are appropriate when these elements are in the positions shown in the drawings. If the descriptions of the positions of these elements change, these directional indications also change accordingly.

[0042] Please see Figures 1 to 18 An embodiment of the microsphere encapsulation equipment provided by the present invention mainly includes a machine base 1 and a test tube feeding mechanism 2, a microsphere dispensing mechanism 3, a heat sealing mechanism 4, and a transfer mechanism 5 respectively disposed on the machine base 1. The machine base 1 is provided with a test tube feeding station 11, a microsphere dispensing station 12, and a test tube sealing station 13. The test tube feeding mechanism 2 is configured to feed multiple test tubes in batches to the test tube feeding station 11. The microsphere dispensing mechanism 3 is configured to simultaneously dispense microspheres into multiple test tubes located at the microsphere dispensing station 12. The heat sealing mechanism 4 is configured to simultaneously seal multiple test tubes located at the test tube sealing station 13. The transfer mechanism 5 includes a transfer component 51 that can move relative to the machine 1. The transfer component 51 is configured to receive multiple test tubes from the test tube feeding mechanism 2 to the test tube feeding station 11 in batches. The transfer component 51 moves so that each test tube can be switched sequentially between the test tube feeding station 11, the microsphere dispensing station 12, and the test tube sealing station 13.

[0043] In the microsphere packaging equipment of this invention, the transfer component 51 of the transfer mechanism 5 first receives multiple test tubes fed to the test tube loading station 11 by the test tube loading mechanism 2 in batches. Then, it moves to the microsphere dispensing station 12, where the microsphere dispensing mechanism 3 simultaneously dispenses microspheres into each test tube. After the microsphere dispensing is completed, the transfer component 51 moves again, carrying the batch of test tubes containing microspheres to the test tube sealing station 13. The heat sealing mechanism 4 simultaneously heat seals the openings of each test tube. Finally, the transfer component 51 removes the packaged batch of test tubes and outputs the finished product. Thus, by sequentially switching between three fixed stations and coordinating the batch synchronous operations of each mechanism at each station, efficient, stable, and continuous fully automated batch packaging of microspheres is achieved.

[0044] Specifically, the microsphere packaging equipment of this invention replaces the traditional "single-piece flow mode" with a "batch flow mode," reducing the frequency of operation of each actuator to 1 / N times (where N is the number of batches per batch) under the same output, thereby significantly shortening the batch production cycle and improving production efficiency. Simultaneously, due to the significant reduction in the frequency of operation of each actuator, the cumulative wear of mechanical transmission components is correspondingly reduced, which is beneficial for maintaining the operational accuracy and uniformity of each actuator over a long period, thus meeting the high-precision and high-stability production requirements of large-scale industrial mass production.

[0045] It should be noted that the test tube loading station 11, microsphere dispensing station 12, and test tube sealing station 13 can be arranged in different ways. The three stations can be distributed in a straight line, L-shape, U-shape, or arc around a center on the same horizontal plane to facilitate horizontal flow transfer. Alternatively, the three stations can be arranged vertically in a stacked manner to form a three-dimensional vertical layout. This method is beneficial for significantly reducing the equipment footprint, especially suitable for cleanrooms or scenarios with limited work surfaces. Furthermore, the three stations can also be arranged in a three-dimensional layout combining horizontal and vertical directions. For example, some stations may be located on the same horizontal plane while another station is located above or below that horizontal plane in a staggered position. Regardless of whether a horizontal, vertical, or combined horizontal and vertical three-dimensional layout is used, as long as the three stations are distributed in different positions in space according to the process sequence of loading, dispensing, and sealing, and the transfer unit 51 can orderly transfer batches of test tubes between the three stations, it falls within the scope of the arrangement methods disclosed in this specification.

[0046] It should be noted that the movement of the transfer component 51 can be configured according to the different orientations of the aforementioned workstations: when the three workstations are arranged horizontally, the transfer component 51 can be configured to perform unidirectional linear reciprocating translation in the horizontal plane, rotational motion around the vertical axis, or a composite planar motion composed of multi-axis linkage. When the three workstations are arranged vertically, the transfer component 51 can be configured to perform lifting and reciprocating translation in the vertical plane, or flipping motion around the horizontal axis. When the three workstations are arranged in a three-dimensional non-plane configuration combining horizontal and vertical, the transfer component 51 can adopt a composite form of horizontal and vertical linear translation, a composite form of horizontal and vertical rotational motion, or a spatial multi-axis linkage, etc. Any single-action or composite motion method, including but not limited to the above, that can drive the transfer component 51 to sequentially transfer the batch of test tubes to the test tube loading station 11, the microsphere dispensing station 12, and the test tube sealing station 13, shall be considered an equivalent implementation of the "activity" referred to in this application.

[0047] Please see Figures 1 to 4In a specific embodiment, the transfer component 51 can rotate horizontally relative to the machine base 1 and has a horizontally arranged disc-shaped structure. A vertically penetrating clamping groove 5111 is provided on the outer edge of the transfer component 51. Multiple clamping grooves 5111 are arranged adjacently along the circumference of the transfer component 51, forming a clamping groove group 511. Each clamping groove 5111 in the clamping groove group 511 is configured to hold one test tube, or the clamping groove 5111 extends in one direction and is configured to hold multiple test tubes in batches, with the multiple test tubes arranged along the extension direction of the clamping groove 5111. The test tube loading station 11, the microsphere dispensing station 12, and the test tube sealing station 13 are horizontally arranged and circumferentially distributed around the rotation center of the transfer component 51. The transfer component 51 rotates horizontally to drive the clamping groove assembly 511 to switch sequentially between the test tube loading station 11, the microsphere dispensing station 12, and the test tube sealing station 13; or, the transfer component 51 rotates horizontally to drive the clamping groove 5111 extending in one direction to switch sequentially between the test tube loading station 11, the microsphere dispensing station 12, and the test tube sealing station 13.

[0048] By causing the transfer component 51 to rotate horizontally, multiple test tubes are carried sequentially to the test tube loading station 11, the microsphere dispensing station 12, and the test tube sealing station 13, which are arranged in a circle, thereby completing the three processes of test tube loading, microsphere dispensing, and test tube sealing. It features a compact structure, the shortest station switching path, high positioning accuracy, simple control logic, and stable and reliable operation.

[0049] In this embodiment, the application adopts the first implementation method in the above embodiments, that is, using multiple clamping grooves 5111 in the clamping groove group 511 to respectively support different test tubes.

[0050] In a specific embodiment, multiple clamping slot groups 511 are provided, and each clamping slot group 511 is arranged at intervals along the circumference of the transfer member 51. When a clamping slot group 511 is located at the test tube loading station 11, different clamping slot groups 511 are respectively located at the microsphere dispensing station 12 and the test tube sealing station 13, thereby enabling parallel operation in an assembly line and further improving production efficiency.

[0051] Please see Figure 3 and Figure 4 In this embodiment, the transfer mechanism 5 further includes a limiting ring 52. The limiting ring 52 is coaxially arranged with the transfer component 51 and is arc-shaped. The limiting ring 52 is sleeved on the outside of the transfer component 51 and is configured to form a clearance when each clamping groove 5111 in the clamping groove group 511 receives different test tubes (or the clamping groove 5111 extending in one direction receives multiple test tubes in batches). During the entire process of the clamping groove group 511 (the clamping groove 5111 extending in one direction) carrying multiple test tubes to realize microsphere encapsulation and test tube sealing, the limiting ring 52 can restrict the test tubes from coming out of the corresponding slots along the radial outside of the transfer component 51.

[0052] The limiting ring 52 forms a radial obstruction on the outer edge of the transfer component 51. When the transfer component 51 rotates, the test tube tends to dislodge radially outward from the clamping groove 5111 under the action of centrifugal force. The inner wall of the limiting ring 52 is precisely against the outer side of the test tube, effectively preventing the test tube from being thrown out, thereby ensuring the safety of the transferred test tube. On the other hand, the function of avoiding during loading and limiting during transfer can be switched without the need for a movable switch, which has the advantages of high reliability and low installation cost.

[0053] It should be noted that the clamping groove 5111 provides circumferential limiting, and the limiting ring 52 provides radial limiting. The two work together to ensure that the test tube maintains a stable posture throughout the entire packaging process.

[0054] In a specific embodiment, a feeding station 14 is also provided on the horizontal side of the machine base 1 or on the machine base 1. The feeding station 14 is located on the same circumference as the test tube loading station 11, the microsphere dispensing station 12, and the test tube sealing station 13, and is located on the side of the test tube sealing station 13 facing away from the microsphere dispensing station 12. The transfer mechanism 5 also includes a bracket 53, a drive member 54, and a baffle 55 located below the transfer member 51. The bracket 53 has an inverted U-shaped structure and includes a first plate 531, a second plate 532, and a third plate 533 connected in sequence. The first plate 531 and the second plate 532 are respectively connected to the machine base 1. The drive member 54 is located inside the bracket 53, and the output shaft of the drive member 54 passes through the third plate 533 and is connected to the transfer member 51. Baffle 55 is disposed on one of the first plate 531 and the second plate 532. Baffle 55 includes an outlet section 551, which is located on the unloading station 14 and is arranged outwardly at an angle from the side near the test tube sealing station 13 to the side away from the test tube sealing station 13.

[0055] The bracket 53 forms a bridge-like support structure spanning the machine base 1, which is the basis for the stability of the transfer mechanism 5. The drive component 54 is used to provide a power source to drive the transfer component 51 to rotate horizontally, and forms a compact layout with the bracket 53 and the transfer component 51. When the transfer component 51 rotates and brings the sealed test tube from the sealing station to the unloading station 14, the test tube rotates horizontally with the transfer component 51 and enters the area where the outlet section 551 is located. Since the baffle 55 is fixed and the transfer component 51 continues to rotate, the test tube body abuts against the inclined outlet section 551 as it contacts the outlet section 551. As the transfer component 51 continues to rotate, the test tube is gradually pushed outward, and finally comes out of the clamping groove 5111 and slides into the collection container below, thus automatically completing the unloading of the finished product after the feeding, dispensing and sealing processes, realizing a fully automated closed loop. Specifically, automatic feeding can be achieved by utilizing the rotation of the transfer component 51 and the cooperation of the guide section, which has the advantages of simple structure, high feeding efficiency and no need to add a power source.

[0056] In this embodiment, the baffle 55 further includes a horizontally extending connecting segment 552, which is connected to one of the plates of the lead-out segment 551 and the bracket 53, respectively.

[0057] In this embodiment, the transfer mechanism 5 further includes a positioning sensor 56, which is disposed on the other side of the first plate 531 and the second plate 532 to achieve high-precision closed-loop control. In a preferred embodiment, the positioning sensor 56 is a photoelectric switch, which includes a transmitting end and a receiving end. A positioning piece 57 is connected to the bottom of the transfer component 51. When the transfer component 51 rotates horizontally, the positioning piece 57 can enter or exit between the transmitting end and the receiving end. The photoelectric switch and the positioning piece 57 achieve non-contact detection, which is fast and has no mechanical wear.

[0058] Please see Figures 5 to 10 In a specific embodiment, the test tube loading mechanism 2 includes a base 21, a material box 22, and a lifting seat 23. The base 21 has an inclined output channel 211, and the lower side of the output channel 211 can dock with the clamping groove 5111 located at the test tube loading station 11. The material box 22 is connected to the base 21 and is located on the horizontal side of the output channel 211. The material box 22 has a funnel-shaped structure, and the interior of the material box 22 has a material cavity 225 capable of loading test tubes in batches. The bottom of the material box 22 has an opening 226 communicating with the material cavity 225. The lifting seat 23 is located below the material cavity 225. The top of the lifting seat 23 has an upward-facing receiving groove 231 with a slot 2311. The receiving groove 231 is inclined, and the lower side of the receiving groove 231 forms an output end 2312. The lifting seat 23 is configured to be able to rise and fall relative to the base 21. When the lifting seat 23 rises relative to the base 21, it can gradually enter the material chamber 225 through the opening 226, and allow several test tubes to be gradually inserted through the slot 2311 and arranged in sequence in the receiving slot 231. After the arrangement, each test tube can be output from the output end 2312 to the output channel 211 in sequence when the lifting seat 23 rises to the preset height.

[0059] Because the material box 22 has a funnel-shaped structure, after the test tubes are put into the material chamber 225 in batches, they will gather towards the bottom opening 226 under the action of gravity. When feeding is required, the lifting seat 23 is driven to rise relative to the base 21. The top of the lifting seat 23 first enters the material chamber 225 through the opening 226 at the bottom of the material box 22 and contacts the test tubes near the opening 226. As the lifting seat 23 continues to rise, it continuously lifts and pushes these test tubes, causing them to gradually insert into the receiving groove 231 through the slot 2311. Under the action of gravity, they slide along the inclined receiving groove 231, thus automatically forming an arrangement in the receiving groove 231 and temporarily storing them there. When the lifting seat 23 rises to the preset height, the test tubes arranged in the receiving groove 231 are discharged sequentially from the output end 2312 under the action of gravity and continuously fed through the inclined output channel 211. Therefore, the batch loading, orderly arrangement and continuous feeding of test tubes can be completed by only one upward movement of the lifting seat 23 relative to the base 21, resulting in high output per action and thus improving feeding efficiency.

[0060] It should be noted that multiple test tubes are arranged in a single row within the output channel 211. Under the influence of gravity, each test tube is continuously conveyed sequentially towards the lower side along the inclined direction of the output channel 211. When the transfer member 51 rotates horizontally so that the first clamping slot 5111 in the clamping slot group 511 is aligned with the lower side outlet of the output channel 211, the test tube at the very front of the output channel 211 falls into the clamping slot 5111 under gravity. Subsequently, the transfer member 51 continues to rotate horizontally by one indexing angle, aligning the second clamping slot 5111 with the lower side outlet of the output channel 211, and the next test tube falls into that slot. This process continues until all clamping slots 5111 in the clamping slot group 511 are filled with test tubes, through successive indexing rotations. Thus, by coordinating the intermittent indexing rotation of the transfer component 51 with the continuous feeding of the output channel 211, a seamless batch connection between the test tube feeding mechanism 2 and the transfer mechanism 5 is achieved.

[0061] Please see Figure 6 and Figure 7 In this embodiment, a clearance opening 22122 is provided on the side of the material box 22 near the output channel 211. When the lifting seat 23 rises relative to the base 21 to the lower side of the receiving groove 231 and forms a connection with the higher side of the output channel 211 through the clearance opening 22122, each test tube arranged in the receiving groove 231 can be sequentially output from the output end 2312 to the output channel 211.

[0062] It should be noted that the outer ring of the test tube is provided with a flange, and the flange is arranged close to the top opening of the test tube. The cooperation state of the test tube, the receiving groove 231 and the output channel 211 is as follows: when the test tube is inserted into the receiving groove 231, the bottom of the test tube falls into the receiving groove 231, and the flange is placed on the edge of the groove 2311 of the receiving groove 231, so that the test tubes are arranged in sequence along the inclined direction of the receiving groove 231. When the lifting seat 23 rises to the preset height, the edge of the slot 2311 on the lower side of the receiving groove 231 is at the same height as the top edge of the output channel 211 on the higher side. The flange can move along the edge of the slot 2311 of the receiving groove 231 to the top edge of the output channel 211. At this time, the bottom of the test tube enters the output channel 211. The test tube can continue to slide along the inclined direction of the output channel 211 under the action of gravity and be received by the clamping groove 5111 located at the test tube loading station 11 and connected to the output channel 211. Specifically, the test tube body passes through the clamping groove 5111 and the flange is mounted above the receiving groove 231.

[0063] It should be noted that the length of the receiving groove 231 (and the groove opening 2311) is not less than the sum of the test tube length and the outer diameter of the flange, so as to form redundant accommodating space in the length direction of the receiving groove 231. This allows at least two test tubes to fall into the receiving groove 231 simultaneously and be arranged side by side during the lifting process of the lifting seat 23, thereby enabling multiple test tubes to be output in a single lifting action and improving feeding efficiency. The width of the receiving groove 231 (and the groove opening 2311) is greater than the outer diameter of the test tube and smaller than the outer diameter of the flange, to ensure that the main body of the test tube can fall into the receiving groove 231, while the flange is engaged with the outer edge of the groove opening 2311 to form a sliding support. The depth of the receiving groove 231 is greater than the distance from the flange to the bottom of the test tube. When the flange is placed on the edge of the groove 2311 of the receiving groove 231, there is a gap between the bottom of the test tube and the bottom of the receiving groove 231. This ensures that the bottom of the test tube will not touch the bottom of the groove and be "push up" during the process of inserting the test tube into the receiving groove 231, thereby ensuring that the flange does indeed bear the full support force and that the test tube can slide smoothly.

[0064] In this embodiment, the test tube is 40.4 mm long, the distance from the flange to the bottom of the test tube is 29 mm, the outer diameter of the test tube is 7.8 mm, and the outer diameter of the flange is 10 mm. The receiving groove 231 is 53.5 mm long, 8.4 mm wide, and 32 mm deep.

[0065] Please see Figure 8In a specific embodiment, the material box 22 includes a housing 221 and a guide plate 222 and a baffle plate 223, both of which are oscillatingly connected to the housing 221. The housing 221 has a hollow cylindrical structure and is vertically arranged on the base 21. The guide plate 222 is arranged at an angle and, together with the housing 221, defines the discharge chamber 225. An opening 226 is provided between the lower side of the guide plate 222 and the housing 221, and the guide plate 222 is configured to oscillate during the upward movement of the lifting seat 23 relative to the base 21. The baffle plate 223 is disposed inside the housing 221, and is arranged vertically opposite to the guide plate 222, covering the opening 226.

[0066] The housing 221 provides space and lateral restraint for the test tubes, while the guide plate 222, with its tilt angle, guides the test tubes to flow orderly towards the opening 226 at the bottom. Specifically, test tubes placed into the housing 221 from above fall onto the baffle plate 223 and the guide plate 222. The baffle plate 223 prevents the test tubes from falling directly through the opening 226 and forms a height-limiting channel with the guide plate 222, preventing a large number of test tubes from accumulating and causing blockage. It also adjusts the posture of the test tubes, ensuring that a small number of test tubes near the opening 226 can be guided orderly into the receiving groove 231. The guide plate 222 swings, causing the baffle plate 223 to swing through the test tubes. This alternating or synchronous swinging of the guide plate 222 and the baffle plate 223 applies a slight vibration to the test tubes in the material chamber 225, thereby reducing the phenomenon of test tubes getting stuck and allowing the test tubes to move smoothly towards the opening 226. Thus, this embodiment provides a specific implementation method for the material box 22 to achieve controllable material feeding.

[0067] Please see Figure 8 In this embodiment, the baffle plate 223 includes a bent body 2231 and a blocking portion 2232. One side of the body 2231 has a circular hole and is connected to the housing 221 via a rotating shaft passing through the circular hole, located directly above the opening 226. The other side has an oblong hole and is connected to the housing 221 via a rotating shaft passing through the oblong hole, allowing for a swing-connected relationship with the housing 221. The blocking portion 2232 is positioned near the side with the oblong hole, and a gap is formed between the blocking portion 2232 and the guide plate 222 for the test tube to pass through. This gap narrows along the length of the opening 226 from the side away from the output end 2312 towards the side near the output end 2312 of the receiving groove 231, thereby reducing the accumulation of test tubes on the side where the output end 2312 is located.

[0068] It should be noted that the baffle plate 223 can also limit the maximum height of the lifting seat 23 and prevent the test tube from being pushed out of the material chamber 225 during the upward movement of the lifting seat 23, thereby ensuring the stability and controllability of the material taking process.

[0069] Please see Figure 6 , Figure 7 and Figure 10 In a specific embodiment, the material bin 22 further includes rollers 224, which are connected to and located below the guide plate 222. The test tube feeding mechanism 2 also includes a push plate 24, which is connected to the lifting seat 23. The lifting seat 23 rises relative to the base 21, enabling the push plate 24 to contact and push the rollers 224 upwards, causing the guide plate 222 to swing. By utilizing the upward movement of the lifting seat 23 itself, the guide plate 222 can be directly driven to swing by the push plate 24 pushing the rollers 224 upwards. This eliminates the need for additional independent drive mechanisms 26 such as motors 333, cylinders, or cams 332, making the overall structure more compact and cost-effective. Furthermore, the push plate 24 and rollers 224 are in rolling contact, resulting in a smoother pushing action and significantly reducing wear and energy loss, thereby improving the overall service life of the mechanism.

[0070] In this embodiment, the guide mechanism 25 includes a slide rail 251 and a slide block 252 mounted on the base 21, with the slide block 252 connected to the push plate 24. The guide mechanism 25 provides precise and reliable vertical movement guidance for the lifting movement of the lifting seat 23.

[0071] In this embodiment, a position sensor for detecting the lifting motion of the lifting seat 23 / push plate 24 is provided on the base 21, and an optocoupler for detecting whether there is a shortage of material in the material cavity 225 and for detecting the condition of the test tube in the output channel 211 is provided outside the conveying channel and outside the material box 22, respectively.

[0072] Please see Figures 6 to 10 In a specific embodiment, the guide plate 222 includes at least two sub-plates 2221 arranged sequentially in an inclined direction. One sub-plate 2221 arranged near the opening 226 is fixedly connected to the housing 221. At least one of the remaining sub-plates 2221 is configured to be oscillatingly connected to the housing 221 and to be able to oscillate during the process of the lifting seat 23 rising relative to the base 21.

[0073] When the lifting seat 23 rises, the cooperation of the push plate 24 and the roller 224 triggers the swingable sub-plate 2221 to swing, which is transmitted to the blocking plate 223 through the test tube. The sub-plate 2221 and the blocking plate 223 work together to agitate the test tube in the material cavity 225 to prevent jamming. Since the sub-plate 2221 near the opening 226 is fixed, the size and position of the opening 226 remain unchanged, thus ensuring that the test tube can fall stably and controllably into the receiving groove 231 during the rising process of the lifting seat 23.

[0074] The housing 221 includes a support plate 22121, which stands upright on the base 21 and covers the outside of the lifting seat 23. The guide plate 222 has an extension plate 22211, which extends downward from the lower side of the guide plate 222 and forms a lifting channel 227 with the support plate 22121. The lifting channel 227 communicates with the material cavity 225 through an opening 226. The lifting seat 23 passes through the lifting channel 227 and can slide upward or downward along the lifting channel 227 when the lifting seat 23 rises or falls relative to the base 21.

[0075] The lifting channel 227 provides vertical guidance for the lifting movement of the lifting seat 23, avoiding swaying and shaking, and improving the reliability and stability of the lifting process. The support plate 22121 is erected on the base 21 to ensure that the material box 22 can be stably set above the lifting seat 23. The support plate 22121 covers the outside of the lifting seat 23. On the one hand, it can prevent external foreign objects (such as dust and debris) from directly contacting the lifting seat 23. On the other hand, it can also prevent operators or external objects from accidentally touching the lifting seat 23 during the sliding process of the lifting seat 23, so as to improve safety.

[0076] Please see Figure 5 , Figure 9 and Figure 10 In a specific embodiment, the lifting seat 23 has a connecting hole 232. The test tube feeding mechanism 2 also includes a driving mechanism 26, which includes a rotary driving member 54, a lever 262, and a locking member 263. One end of the lever 262 is connected to the rotary driving member 54, and the other end has a slotted hole 2621. The locking member 263 passes through the slotted hole 2621 and is locked in the connecting hole 232. When the rotary driving member 54 drives one end of the lever 262 to rotate, the other end of the lever 262 drives the lifting seat 23 to rise or fall relative to the base 21 through the locking member 263, and the locking member 263 can slide within the slotted hole 2621.

[0077] Through the coordinated operation of the rotary drive 54, lever 262, locking member 263 and connecting hole 232, the rotary motion can be converted into the vertical lifting of the lifting seat 23. It has the characteristics of compact structure and smooth operation. In addition, the strip hole 2621 allows the locking member 263 to slide along its length direction, which can eliminate the interference of the horizontal displacement generated by the arc motion of the lever 262 on the vertical guide of the lifting seat 23, and avoid the mechanism from jamming or generating additional lateral force.

[0078] In this embodiment, the locking member 263 is a bolt, and the connecting hole 232 is a screw hole. The locking member 263 is locked in the connecting hole 232 by a threaded connection.

[0079] Please see Figure 7 and Figure 8In the above embodiments, the housing 221 includes an upper housing 2211 and a lower housing 2212 connected to each other. The upper housing 2211 has a funnel-shaped structure with a feed inlet 22111 at the top and a feed outlet 22112 at the bottom. The lower housing 2212 has a square cylindrical shape with a cross-sectional profile that matches the feed outlet 22112. The baffle plate 223 and the guide plate 222 are respectively connected to the lower housing 2212.

[0080] It should be noted that in this embodiment, the test tubes are placed into the material box 22 in a random posture. When the lifting seat 23 is in its initial position, the test tubes first fall into the lifting channel 227 through the opening 226. At this time, the flanges of the test tubes whose tube bodies are aligned with the slots 2311 are supported on the edge of the slots 2311, and the tube bodies are suspended or partially inserted into the slots. The test tubes that are not aligned with the slots 2311 are temporarily piled up on the top surface of the lifting seat 23. As the lifting seat 23 continues to rise, the top of the lifting seat 23 gradually passes through the opening 226 and enters the material cavity 225, and the test tubes located above the lifting seat 23 are continuously pushed upward. During this process, the test tubes piled up on the top surface of the lifting seat 23 are continuously adjusted in posture under the combined action of the rising and pushing action of the lifting seat 23 and the limiting and guiding action of the slots 2311 of the receiving slot. The main body of the test tube is gradually inserted into the receiving slot 231 through the slots 2311, while the flanges are supported on the edge of the slots 2311. Because the receiving groove 231 is arranged at an angle, the inserted test tube automatically slides to the lower side (i.e., the direction of the output end 2312) under the action of gravity. The empty space after it slides away is filled by the subsequently inserted test tubes, so that the test tubes are arranged in sequence along the angle.

[0081] When the lifting seat 23 rises to the preset height, the lower side of the receiving groove 231 connects with the output channel 211 through the clearance opening 22122. Each test tube arranged in the receiving groove 231 slides out from the output end 2312 in sequence under the action of gravity and is transported to the downstream station (i.e. the clamping groove 5111 at the test tube loading station 11) via the output channel 211.

[0082] In other embodiments, the test tube is placed into the material box 22 with its bottom facing down, and slides along the inclined direction of the guide plate 222 under the guidance of the guide plate 222, gradually tilting until it reaches the opening 226 between the lower side of the guide plate 222 and the housing 221. Due to the tilted posture of the test tube, the bottom of the test tube cannot be aligned and pass through the opening 226 into the lifting channel 227, but is supported by the guide plate 222 or the inner wall of the housing 221 and held above the opening 226; at the same time, under the limiting action of the baffle plate 223, the upper end of the test tube (i.e., the end with the flange) is restricted within a predetermined range above the opening 226, so that the entire test tube is held at the opening 226 in an inclined posture and will not fall into the lifting channel 227. When the lifting seat 23 rises relative to the base 21, the top of the lifting seat 23 pushes upward to the bottom of the test tube located at the opening 226, causing the test tube to move upward and separate from the opening 226. Then, under the continuous pushing of the lifting seat 23, it is gradually inserted into the receiving groove 231 through the slot 2311 of the receiving groove 231 and arranged.

[0083] Please see Figures 11 to 19 In a specific embodiment, the microsphere dispensing mechanism 3 includes an upper ball seat 31, a lower ball seat 32, and a movable mechanism 33. The upper ball seat 31 has at least two sets of channel groups 314 internally, each channel group 314 including several feed channels 3141. The lower ball seat 32 has at least two discharge channels 321 internally, each discharge channel 321 configured to dispense microspheres into multiple test tubes located at the microsphere dispensing station 12. The discharge channels 321 are located below the channel groups 314 and are vertically offset from the channel groups 314. The movable mechanism 33 includes a push plate 331, which has at least two sets of groove groups 3311. Each groove group 3311 includes storage grooves 33111, the same number as the feed channels 3141 of the channel groups 314. The pusher plate 331 is configured to reciprocate horizontally between the feed channel 3141 and the discharge channel 321, so that the storage tank 33111 has a receiving state and a releasing state. When the pusher plate 331 moves to a position where each feed channel 3141 of each channel group 314 is vertically aligned with each storage tank 33111 of a tank group 3311, the storage tank 33111 is in the receiving state, and each storage tank 33111 can receive a microsphere released from the corresponding feed channel 3141. When the pusher plate 331 moves to a position where each storage tank 33111 of each tank group 3311 is vertically aligned with a discharge channel 321, the storage tank 33111 is in the releasing state, and the microspheres in each storage tank 33111 enter the same discharge channel 321.

[0084] Because the channel group 314 in the upper ball seat 31 and the discharge channel 321 in the lower ball seat 32 are vertically staggered, and the pusher plate 331 can reciprocate between two extreme positions, the same set of storage tanks 33111 are vertically opposite to the feed channel 3141 (receiving material) and the discharge channel 321 (releasing material) at different horizontal positions, thereby achieving stable feeding of microspheres. By setting up multiple sets of storage tanks 33111, channel groups 314, and multiple discharge channels 321, the pusher plate 331 can simultaneously feed microspheres into multiple test tubes after completing one cycle of "receiving → translation → releasing material". Compared with single-channel feeding one by one, the output per cycle of this scheme is proportional to the number of channels, thus significantly improving the unit time output of microsphere packaging.

[0085] Please see Figures 11 to 15 In a specific embodiment, the pusher plate 331 can move relative to the upper ball seat 31 along a first horizontal direction D1. Each feed channel 3141 of the channel group 314 and each storage tank 33111 of the tank group 3311 are arranged along a second horizontal direction D2 that is perpendicular to the first horizontal direction D1. The push plate 331 has a number of forming part groups 3312 that are the same as the number of trough groups 3311. The forming part group 3312 includes a plurality of forming parts 33121 arranged sequentially in the second horizontal direction D2. Each forming part 33121 has a storage trough 33111. In the second horizontal direction D2, the forming part group 3312 is in a stepped shape with the height of each forming part 33121 increasing or decreasing sequentially, so that the vertical distance between each storage trough 33111 in the same trough group 3311 and the material outlet 32121 of the corresponding discharge channel 321 is different, and the microspheres in each storage trough 33111 can enter the same discharge channel 321 sequentially.

[0086] When the storage tank 33111 is in the receiving state, each feeding channel 3141 of the channel group 314 is vertically opposite to each storage tank 33111 of the corresponding tank group 3311. When the storage tank 33111 is in the release state, each storage tank 33111 in the same tank group 3311 is located above the feed port 32121 of the corresponding discharge channel 321. Since the vertical distance between each storage tank 33111 and the feed port 32121 is different, the falling distance of the microspheres falling from each storage tank 33111 at the same time is different, which in turn produces a time difference. This allows multiple microspheres to pass through the feed port 32121 in sequence and orderly, fall into the discharge channel 321, and enter the test tube. This enables the same test tube to obtain a stable and accurate number of microspheres. It also solves the problems of inlet blockage, microsphere collision and inaccurate microsphere counting caused by multiple microspheres rushing into the feed port 32121 at the same time. This improves the stability and accuracy of the packaging process and can meet the requirements of high-precision production.

[0087] Please see Figures 11 to 14as well as Figure 16 In a specific embodiment, the discharge channel 321 includes a main channel 3211 and a secondary channel 3212 that are connected to each other. The main channel 3211 extends vertically and forms a discharge port 32111 at its bottom end. The radial dimension of the main channel 3211 is configured to allow only a single microsphere to pass through. The secondary channel 3212 extends along a second horizontal direction D2 and is located above the main channel 3211. The top end of the secondary channel 3212 forms a feed port 32121. When the storage tank 33111 is in the release state, in the same tank group 3311, the storage tank 33111 with the shortest vertical distance to the feed port 32121 is arranged vertically opposite to the main channel 3211. The remaining storage tanks 33111 are arranged vertically opposite to the secondary channel 3212. The secondary channel 3212 is configured to guide the microspheres released from the other storage tanks 33111 into the main channel 3211 in an orderly manner.

[0088] The secondary channel 3212 is used to provide horizontal buffering and orderly guidance, ensuring that the microspheres released from the storage tank 33111 can enter the main channel 3211 in sequence. The main channel 3211 can provide precise guidance for these microspheres to enter the test tube (or other containers with narrow entrances that only allow one microsphere to pass through), thereby further improving the overall accuracy, stability and anti-clogging performance of the operation.

[0089] It should be noted that the bottom of the secondary channel 3212 has a guide surface for guiding the microspheres. The guide surface extends smoothly from the feed port 32121 towards the entrance of the main channel 3211, so as to guide the microspheres released into the secondary channel 3212 into the main channel 3211 in an orderly manner. In one specific embodiment, the guide surface is an inclined plane that is inclined relative to the horizontal plane, so that the microspheres slide smoothly by gravity. In another specific embodiment, the guide surface is a downwardly concave arc-shaped curved surface (or arc surface) to buffer and decelerate the falling microspheres, and to automatically concentrate the microspheres to the entrance of the main channel 3211 by using the curvature of the arc surface. In other embodiments, the guide surface can also be a composite curved surface composed of inclined sections and arc sections, as long as it can ensure that the microspheres enter the main channel 3211 in a single and orderly manner.

[0090] Please see Figure 13 In a specific embodiment, the lower ball seat 32 has a detection hole that connects to the interior of the main channel 3211. The microsphere dispensing mechanism 3 also includes a counting sensor 34, which is located outside the main channel 3211 and counts the microspheres falling into the main channel 3211 through the detection hole.

[0091] Please see Figure 14 and Figure 17In a specific embodiment, the upper ball seat 31 is provided with a guide groove 3111, which is formed through in the first horizontal direction D1 and is adapted to the stepped contour of the forming part assembly 3312. The forming part assembly 3312 is movably inserted into the guide groove 3111. When the push plate 331 moves to the receiving state, the lower sidewall of the guide groove 3111 blocks the bottom opening 226 of each storage tank 33111. When the push plate 331 moves to the releasing state, the solid part of the forming part 33121 located next to the storage tank 33111 moves to the bottom of the corresponding feeding channel 3141 to block the outlet of the feeding channel 3141.

[0092] The guide groove 3111 provides installation space and horizontal movement guidance for the push plate 331. Its lower sidewall provides a bottom seal for each storage tank 33111 when the push plate 331 moves to correspond vertically with each feeding channel 3141, ensuring that the microspheres can be stably and reliably retained within the storage tank 33111. Furthermore, the solid portions of each forming part 33121 without storage tanks 33111 can form a seal below each feeding channel 3141 during the release of microspheres from each storage tank 33111 to the discharge channel 321, preventing the microspheres from accidentally falling. Therefore, the above embodiment provides a specific and reliable cooperative structure for the upper ball seat 31 and the push plate 331, ensuring stable feeding and discharging of each storage tank 33111, with a simple structure and reliable operation.

[0093] Please see Figure 14 and Figure 17 In a specific embodiment, the upper ball seat 31 includes a body 311 and a cover 312. The body 311 has guide grooves 3111 and feed grooves 3112 corresponding to the number of feed channels 3141, with one side of the feed grooves 3112 open. The cover 312 covers the open side of the body 311 with the feed grooves 3112, forming feed channels 3141 together with the feed grooves 3112. The body 311 also has air holes 3113 communicating with each feed channel 3141, and an air connector 313 for connecting the air holes 3113 to an external air source. The cover 312 has a clearance opening 3121 for avoiding the forming assembly 3312.

[0094] The vent 3113 is connected to an external air source through the air connector 313, and the airflow is used to force the microspheres in each feeding channel 3141 to fall, thereby overcoming the problem of poor material falling caused by static electricity, friction or channel adsorption, and improving the reliability and consistency of material receiving. On the other hand, the body 311 and the cover 312 are set separately, and the feeding groove 3112 on the body 311 has an open structure, which facilitates the overall processing, assembly and cleaning maintenance.

[0095] Please see Figure 17In this embodiment, each feed trough 3112 has an air hole 3113 on the trough wall facing away from the open side.

[0096] In this embodiment, the two sets of forming part groups 3312 are arranged in a mirror image relative to the first horizontal direction D1 and are movably inserted into the guide groove 3111. Each forming part 33121 in one forming part group 3312 moves from the side closer to the other forming part group 3312 to the side farther away from the other forming part group 3312. On one hand, the mirror symmetry ensures a symmetrical distribution of gravity on the push plate 331 in the orthogonal horizontal direction, resulting in no lateral deflection torque and smoother movement when the push plate 331 moves. On the other hand, the two sets of forming part groups 3312 share the same guide groove 3111, resulting in a compact structure and high synchronization of movement. On the other hand, since the height decreases in opposite directions, the inner side of both groups is the highest point and the outer side is the lowest point. The lower storage tank 33111 has a shorter falling time. Therefore, both groups discharge materials from the outer side to the inner side in sequence, with consistent discharge timing. This also avoids positional interference between the two containers that are connected to the two main channels 3211 respectively, while reserving sufficient operating space for downstream processes such as robotic arm operation and container conveying.

[0097] In a specific embodiment, each channel group 314 is provided with two feeding channels 3141. The microsphere dispensing mechanism 3 also includes a microsphere box 35, which is located above the upper ball seat 31. The microsphere box 35 has a first cavity and a second cavity that are not interconnected. The first cavity is connected to one of the feeding channels 3141 of the two channel groups 314, and the second cavity is connected to the other feeding channel 3141 of the two channel groups 314.

[0098] By setting up a microsphere box 35 with two independent cavities, the first cavity simultaneously supplies material to one of the feeding channels 3141 of the two channel groups 314, and the second cavity simultaneously supplies material to the other feeding channel 3141 of the two channel groups 314. Specifically, the first cavity and the second cavity can be filled with the same or different microspheres. When the two cavities are filled with the same microspheres, each container can obtain two of the same type of microspheres, achieving double the filling amount. When the two cavities are filled with different microspheres, each container can obtain two different types of microspheres, achieving mixed filling. This achieves the technical effect of dual-station parallel operation, flexible feeding, and consistent filling, and can adapt to various filling needs.

[0099] Similarly, each channel group 314 can be equipped with other numbers of feeding channels 3141, and the number of cavities inside the microsphere box 35 is the same as the number of feeding channels 3141. Each cavity is connected to a corresponding feeding channel 3141 in each channel group 314, and each cavity can be filled with the same or different microspheres to achieve mixed packaging of different types and quantities of microspheres.

[0100] Please see Figure 11 , Figure 12 , Figure 18 and Figure 19 In this embodiment, the microsphere box 35 includes an upper box body 351 and a lower box body 352. The upper box body 351 has a hollow cylindrical structure and is divided into two cavities 3511 inside. The lower box body 352 is located below the upper box body 351 and is provided with two upward-facing guide channels 3521. The two guide channels 3521 are respectively connected to the two cavities 3511. One guide channel 3521 is provided with two first inlets 3523 that are respectively connected to one of the feed channels 3141 of the two channel groups 314. The other guide channel 3521 is provided with two second inlets 3524 that are respectively connected to the other feed channel 3141 of the two channel groups 314.

[0101] By designing the microsphere box 35 as an upper box 351 with two cavities 3511 separated by a lower box 352 with a guide channel 3521, the two cavities 3511 of the upper box 351 are used to store microspheres, and the two guide channels 3521 of the lower box 352 distribute the microspheres to the corresponding feed channels 3141 of the two channel groups 314 at the same time. It has the characteristics of compact structure, uniform feeding, easy feeding and cleaning.

[0102] Please see Figure 18 and Figure 19 In a further embodiment, two flow channels 3522 are formed on the sidewalls of both guide channels 3521. The bottom end of the flow channel 3522 of one guide channel 3521 forms a first feed inlet 3523, and the bottom end of the flow channel 3522 of the other guide channel 3521 forms a second feed inlet 3524. By setting two flow channels 3522 on the sidewalls of the guide channels 3521, the microspheres in each guide channel 3521 are directed to the corresponding feed channel via the flow channel 3522, thus achieving precise, uniform, and smooth transport of microspheres from the microsphere box 35 to the feed channel 3141.

[0103] Please see Figures 11 to 15In a specific embodiment, the push plate 331 is movable relative to the upper ball seat 31 along a first horizontal direction D1. The push plate 331 has an oblong hole 3313 extending along a second horizontal direction D2 perpendicular to the first horizontal direction D1. The movable mechanism 33 also includes a cam 332 and a motor 333. The cam 332 is rotatably housed within the oblong hole 3313 and abuts against the sidewall of the oblong hole 3313 in the first horizontal direction D1. The motor 333 drives the cam 332 to rotate, thereby switching the push plate 331 between a receiving state and a releasing state. When the minimum radius portion of the cam 332 abuts against the sidewall of the oblong hole 3313 near the storage trough 33111, the storage trough 33111 is in a receiving state. When the maximum radius portion of the cam 332 abuts against the sidewall of the oblong hole 3313 near the storage trough 33111, the storage trough 33111 is in a releasing state. The rotational motion of cam 332 is converted into the reciprocating linear motion of push plate 331, which features compact structure, accurate positioning, low cost and smooth motion.

[0104] Please see Figure 14 and Figure 15 In a specific embodiment, the active mechanism 33 further includes a support 334, a connecting cap 335, and a position sensor 336. The support 334 has a groove 3341 extending through both sides of the support 334 in a first horizontal direction D1. The top and bottom of the support 334 have a first window 3342 and a second window communicating with the groove 3341, respectively. The connecting cap 335 is located above the support 334 and has a positioning strip 3351. The position sensor 336 is located on the top of the support 334. The push plate 331 is slidably inserted into the groove 3341. The cam 332 is located in the groove 3341. The motor 333 is installed below the support 334. Its output shaft 3331 passes through the second window, the cam 332, and the first window 3342 in sequence and is fixedly connected to the connecting cap 335 located above the support 334. The motor 333 rotates to drive the positioning strip 3351 into or out of the detection area of ​​the position sensor 336.

[0105] It should be noted that when the positioning bar 3351 enters the detection area of ​​the position sensor 336, the storage tank 33111 is in the receiving state or the releasing state.

[0106] The output shaft 3331 of the motor 333 passes through the support 334 and the cam 332, and is supported by the first window 3342 and the second window. By cooperating with the position sensor 336 on the positioning strip 3351 on the connecting cap 335 connected to the output shaft 3331 of the motor 333, stable installation of the push plate 331 and accurate detection of its reciprocating motion are achieved. This design features a compact structure, smooth operation, accurate detection, and ease of debugging. In this embodiment, the position sensor 336 is a photoelectric proximity switch. The rotation of the motor 333 drives the positioning strip 3351 to enter or move out between the transmitter and receiver of the photoelectric proximity switch.

[0107] In the above embodiments, the bottom of the lower ball seat 32 is connected to the bottom of the upper ball seat 31, and the support 334 is connected to one side of the upper ball seat 31 in the first horizontal direction D1.

[0108] Please see Figure 14 and Figure 16 In the above embodiments, the top of the lower ball seat 32 is provided with a blocking member 322, which is located between adjacent discharge channels 321 and is used to prevent microballs that should fall into one discharge channel 321 from accidentally rolling into another discharge channel 321.

[0109] Please see Figure 20 In a specific embodiment, the heat-sealing mechanism 4 includes a support base 41 and a test tube holder 42, a cutting female base 43, a heat-sealing cutting assembly 44, and a film conveying assembly 45, all respectively disposed on the support base 41. The test tube holder 42 is movable relative to the support base 41 and is used to support multiple test tubes in the clamping groove assembly 511 located on the test tube sealing station 13. The cutting female base 43 is located above the test tube holder 42 and has multiple through holes corresponding to multiple test tubes. The heat-sealing cutting assembly 44 is located above the cutting female base 43 and includes a cutting plate 441 that is movable relative to the support base 41 and a heat-sealing head 442 disposed on the cutting plate 441. The heat-sealing head 442 has multiple heat-sealing ends 4421 corresponding to multiple through holes. The film conveying assembly 45 is configured to convey film material between the heat-sealing head 442 and the cutting female base 43.

[0110] The test tube holder 42 supports multiple test tubes from bottom to top. When the test tube holder 42 rises relative to the support base 41, it can carry each test tube through the through holes of the punching mother base 43, and make the top of the multiple test tubes flush with the upper surface of the punching mother base 43. At this time, the membrane material conveyed by the membrane conveying assembly 45 covers the top of each test tube. Then, the punching plate 441 descends relative to the support base 41, heat-sealing the membrane material and each test tube into one piece, and simultaneously completing the cutting. Finally, the test tube holder 42 descends to reset, and the punching plate 441 rises to reset, completing one heat-sealing and cutting cycle.

[0111] Through the coordinated action of the test tube holder 42, the punching mother seat 43, the heat sealing and cutting assembly 44, and the film conveying assembly 45, the heat sealing and cutting are completed simultaneously in one action, achieving precise positioning and reliable sealing. Furthermore, the multiple heat sealing heads 442, multiple through holes, and multiple test tubes received by the transfer component 51 correspond one-to-one, realizing multi-station parallel heat sealing and cutting, which is highly matched with the batch flow rhythm of the turntable.

[0112] In this embodiment, the test tube holder 42 includes a base 421 and an elastic element 422, with the elastic element 422 disposed within the base 421. When the test tube holder 42 rises relative to the support base 41, the elastic element 422 undergoes elastic deformation during the process of each test tube penetrating the through holes of the punching female base 43 to compensate for the height error between the test tubes and buffer the impact force generated when the punching plate 441 presses down. Since there may be slight height differences among the multiple test tubes in the clamping groove assembly 511, the elastic element 422 can absorb these differences, ensuring that the opening of each test tube can be tightly fitted to the film material and the force is uniform, avoiding the problem of breakage due to excessive pressure on individual test tubes that are too high or poor sealing due to individual test tubes that are too low. At the same time, the buffering effect of the elastic element 422 also reduces the risk of rigid damage to the test tubes and the heat sealing head 442 caused by the punching impact.

[0113] In this embodiment, the heat-sealing and cutting assembly 44 further includes a heating rod, a temperature sensor, and a heat insulation component. The heating rod and temperature sensor are respectively connected to the heat-sealing head 442, and the heat insulation component is located between the heat-sealing head 442 and the cutting plate 441. After the heating rod heats the heat-sealing head 442 to a preset temperature, the heat-sealing end 4421 directly heat-seales the film material to the test tube opening. The temperature sensor is used to detect the heating status of the heat-sealing head 442, improving the accuracy and safety of the operation. The heat insulation component can effectively prevent heat from being transferred upward to the cutting plate 441 and other components behind the cutting plate 441, ensuring the long-term reliability of the equipment.

[0114] In this embodiment, the membrane conveying assembly 45 includes an unwinding shaft 451, a rewinding shaft 452, a drive roller 453, a driven roller 454, a drive motor, and a damping device. The unwinding shaft 451 is used to mount the membrane roll, and the rewinding shaft 452 is used to rewind the remaining membrane material after heat sealing and cutting. The drive roller 453 and the driven roller 454 are sequentially arranged between the unwinding shaft 451 and the rewinding shaft 452. The motor is connected to the drive roller 453 and the rewinding shaft 452 to drive the membrane material to move from the unwinding shaft 451 to the rewinding shaft 452. The damping device is located on one side of the unwinding shaft 451 and is used to apply a damping force to the unwinding shaft 451. The damping device provides continuous resistance to the unwinding shaft 451, keeping the membrane material taut throughout the conveying process, preventing the membrane material from slackening and wrinkling or shifting, and ensuring that the membrane material covers each test tube opening smoothly.

[0115] In a preferred embodiment, the damping device includes a friction wheel, a friction plate, an elastic element 422, and an adjusting element. The friction wheel is sleeved on the end of the unwinding shaft 451 and can rotate synchronously with the unwinding shaft 451. The friction plate is arranged opposite to the friction wheel and can engage with the friction wheel to generate friction. The elastic element 422 (e.g., a compression spring) is located on the side of the friction plate facing away from the friction wheel and is used to apply an elastic force to the friction plate to press it tightly against the friction wheel. The adjusting element (e.g., an adjusting nut or handwheel) is connected to the elastic element 422 and is used to adjust the compression of the elastic element 422 to change the magnitude of the friction force between the friction plate and the friction wheel. This damping device has a simple structure, low cost, and convenient adjustment, making it suitable for integrated use in automated equipment.

[0116] In this embodiment, the surface of the drive roller 453 is knurled to increase the friction between the surface of the drive roller 453 and the film material. The film conveying assembly 45 also includes a pressing roller 455, which is used to press the film material onto the drive roller 453, thereby ensuring that the drive roller 453 can reliably drive the film material to move precisely. The drive motor and the drive roller 453 are connected by a synchronous belt to ensure precise transmission between the drive motor and the drive roller 453. The drive roller 453 and the take-up shaft 452 are connected by a round belt, and the slippage of the round belt is used to eliminate the difference in linear velocity caused by the increasing diameter of the film roll.

[0117] In this embodiment, a first lifting drive mechanism 46 is provided between the test tube holder 42 and the support base 41, and a second lifting drive mechanism 47 is provided between the punching plate 441 and the support base 41. The first lifting drive mechanism 46 and the second lifting drive mechanism 47 are respectively configured to drive the test tube holder 42 and the punching plate 441 to rise and fall relative to the support base 41.

[0118] For example, the first lifting drive mechanism 46 and the second lifting drive mechanism 47 can be any one of a screw drive mechanism, a synchronous belt drive mechanism, a cylinder, a linear motor 333, or a gear and rack mechanism. For example, when a screw drive mechanism is used, it includes a motor 333 and a screw connected to the motor 333. The screw is threadedly engaged with the test tube holder 42 or the blanking plate 441. The motor 333 drives the screw to rotate, thereby lifting the test tube holder 42 or the blanking plate 441. When a cylinder drive is used, the piston rod of the cylinder is connected to the test tube holder 42 or the blanking plate 441, and lifting is achieved by the extension and retraction of the piston rod. When a synchronous belt drive mechanism is used, the motor drives the test tube holder 42 or the blanking plate 441 to slide along the vertical guide rail via the synchronous belt.

[0119] It should be noted that the microsphere packaging equipment in this embodiment adopts a dual-station parallel configuration. Correspondingly, the transfer component 51 has multiple sets of clamping grooves 511 along the circumferential direction, and each set of clamping grooves 511 has two clamping grooves 5111. In the microsphere dispensing mechanism 3, two sets of channel groups 314 are formed in the upper ball seat 31, two discharge channels 321 are formed in the lower ball seat 32, and two sets of groove groups 3311 are provided on the push plate 331. In the heat sealing mechanism 4, the punching female seat 43 has two through holes corresponding to the test tubes on the two clamping grooves 5111, and the heat sealing head 442 has two heat sealing ends 4421 corresponding to each through hole. Thus, each mechanism can perform different processes on two test tubes at the same time, realizing a dual-station assembly line parallel operation.

[0120] In the above embodiments, the microsphere packaging equipment also includes a control system, which is electrically connected to the test tube feeding mechanism 2, the microsphere dispensing mechanism 3, the heat sealing mechanism 4 and the transfer mechanism 5, respectively, and is used to control the timing and coordination of the actions of each mechanism.

[0121] For example, the control system includes a controller and a human-machine interface (HMI). The controller, employing a programmable logic controller (PLC), a microcontroller, or an industrial control computer, stores the control program and outputs control commands. The HMI is electrically connected to the controller and allows operators to input parameters (e.g., the number of test tubes per batch, the number of microspheres added, the heat-sealing temperature, the heat-sealing time, etc.) and display the equipment's operating status. It should be noted that the connections between components involved in the above embodiments can be selected using various connection methods depending on the actual situation. Preferably, detachable or non-detachable metric connections such as welding, bolt and nut connections, or bolt or screw connections can be used.

[0122] Although the invention has been described with reference to several typical embodiments, it should be understood that the terminology used is illustrative and exemplary, and not restrictive. Since the invention can be embodied in many forms without departing from the spirit or essence of the invention, it should be understood that the above embodiments are not limited to any of the foregoing details, but should be interpreted broadly within the spirit and scope defined by the appended claims. Therefore, all variations and modifications falling within the scope of the claims or their equivalents should be covered by the appended claims.

Claims

1. A microsphere encapsulation device, characterized in that, It includes a machine base and a test tube feeding mechanism, a microsphere dispensing mechanism, a heat sealing mechanism and a transfer mechanism respectively installed on the machine base; The machine is equipped with a test tube loading station, a microsphere dispensing station, and a test tube sealing station; The test tube feeding mechanism is configured to feed multiple test tubes in batches to the test tube feeding station; The microsphere dispensing mechanism is configured to simultaneously dispense microspheres into multiple test tubes located at the microsphere dispensing station; The heat sealing mechanism is configured to simultaneously seal multiple test tubes located at the test tube sealing station; The transfer mechanism includes a transfer component that can move relative to the machine. The transfer component is configured to receive multiple test tubes fed to the test tube feeding station by the test tube feeding mechanism in batches. The transfer component moves to allow each test tube to switch sequentially between the test tube feeding station, the microsphere dispensing station, and the test tube sealing station.

2. The microsphere encapsulation device according to claim 1, characterized in that, The transfer component can rotate horizontally relative to the machine tool and has a horizontally arranged disc-shaped structure. The outer edge of the transfer component is provided with a vertically penetrating clamping groove. Multiple clamping grooves are arranged adjacent to each other along the circumference of the transfer component to form a clamping groove group. Each clamping groove in the clamping groove group is configured to be able to hold one test tube, or the clamping groove extends in one direction and is configured to be able to hold multiple test tubes in batches, and the multiple test tubes are arranged along the extension direction of the clamping groove. The test tube loading station, microsphere dispensing station, and test tube sealing station are arranged horizontally and distributed in a circle around the rotation center of the transfer component. The transfer component rotates horizontally to drive the clamping groove assembly to switch sequentially between the test tube loading station, the microsphere dispensing station, and the test tube sealing station; or, the transfer component rotates horizontally to drive the clamping groove extending in one direction to switch sequentially between the test tube loading station, the microsphere dispensing station, and the test tube sealing station.

3. The microsphere encapsulation device according to claim 2, characterized in that, The machine platform is provided on one horizontal side or on the machine platform, and the unloading station is located on the same circumference as the test tube loading station, the microsphere dispensing station and the test tube sealing station, and is located on the side of the test tube sealing station facing away from the microsphere dispensing station. The transfer mechanism further includes a bracket, a drive unit, and a baffle located below the transfer component; the bracket has an inverted U-shaped structure and includes a first plate, a second plate, and a third plate connected in sequence, the first plate and the second plate being connected to the machine base respectively; the drive unit is located inside the bracket, the output shaft of the drive unit passes through the third plate and is connected to the transfer component; the baffle is provided on one of the first plate and the second plate, the baffle includes an outlet section, the outlet section is located on the unloading station, and is arranged inclined outward from the side near the test tube sealing station to the side away from the test tube sealing station.

4. The microsphere encapsulation device according to claim 2, characterized in that, The test tube loading mechanism includes a base, a material box, and a lifting seat. The base has an inclined output channel, and the lower side of the output channel can connect with the clamping groove located at the test tube loading station. The material box is connected to the base and located on the horizontal side of the output channel. The material box has a funnel-shaped structure, and its interior has a material cavity capable of loading test tubes in batches. The bottom of the material box has an opening communicating with the material cavity. The lifting seat is located below the material cavity. The top of the lifting seat has an upward-facing receiving groove, which is inclined, and the lower side of the receiving groove forms an output end. The lifting seat is configured to be able to rise and fall relative to the base. When the lifting seat rises relative to the base, it can gradually enter the material chamber through the opening and allow several test tubes to be gradually inserted through the slot and arranged in sequence in the receiving slot. The arranged test tubes can be output from the output end to the output channel in sequence when the lifting seat rises to a preset height.

5. The microsphere encapsulation device according to claim 4, characterized in that, The material box includes a shell and a guide plate and a baffle plate, both of which are oscillatingly connected to the shell. The shell has a hollow cylindrical structure and is vertically arranged on the base. The guide plate is arranged at an angle and together with the shell defines the material cavity. An opening is left between the lower side of the guide plate and the shell. The guide plate is configured to oscillate during the process of the lifting seat rising relative to the base. The baffle plate is located inside the shell and is arranged vertically opposite to the guide plate, covering the opening.

6. The microsphere encapsulation device according to claim 5, characterized in that, The material bin also includes rollers, which are connected to the guide plate and located below the guide plate; the test tube feeding mechanism also includes a push plate, which is connected to the lifting seat, and the lifting seat rises relative to the base, which can drive the push plate to contact and push the rollers upward, and cause the guide plate to swing.

7. The microsphere encapsulation device according to claim 2, characterized in that, The microsphere dispensing mechanism includes an upper ball seat, a lower ball seat, and a movable mechanism; The upper ball seat has at least two sets of channels inside, and the channel sets include several feeding channels; The lower ball seat has at least two discharge channels inside, each of which is configured to dispense microspheres into multiple test tubes located at the microsphere dispensing station. The discharge channels are located below the channel group and are vertically offset from the channel group. The active mechanism includes a push plate, which is provided with at least two sets of slots, each set of slots including a storage trough with the same number of feeding channels as the channel group; The pusher plate is configured to reciprocate horizontally between the feed channel and the discharge channel, so that the storage tank has a receiving state and a releasing state. When the pusher moves to the point where each feed channel of each of the channel groups is vertically aligned with each storage tank of a trough group, the storage tank is in the receiving state, and each storage tank can receive a microsphere released from the corresponding feed channel; when the pusher moves to the point where each storage tank of each of the trough groups is vertically aligned with a discharge channel, the storage tank is in the releasing state, and the microspheres in each storage tank enter the same discharge channel.

8. The microsphere encapsulation device according to claim 7, characterized in that, The push plate can move relative to the upper ball seat in a first horizontal direction; Each feeding channel of the channel group and each storage tank of the tank group are arranged along a second horizontal direction that is perpendicular to the first horizontal direction. The push plate has a number of forming sections equal to the number of the slots. Each forming section includes multiple forming sections arranged sequentially in the second horizontal direction. Each forming section has a storage slot. In the second horizontal direction, the forming section group is stepped with the height of each forming section increasing or decreasing sequentially, so that the vertical distance between each storage slot in the same slot group and the material outlet of the corresponding discharge channel is different, and the microspheres in each storage slot can enter the same discharge channel sequentially.

9. The microsphere encapsulation device according to claim 8, characterized in that, The discharge channel includes a main channel and a secondary channel that are connected to each other. The main channel extends vertically and forms a discharge port at its bottom end. The radial dimension of the main channel is configured to allow only a single microsphere to pass through. The secondary channel extends horizontally and is located above the main channel. The top end of the secondary channel forms the material passage. When the storage tank is in the release state, in the same tank group, the storage tank with the shortest vertical distance to the feed port is arranged vertically opposite to the main channel, and the other storage tanks are arranged vertically opposite to the secondary channel. The secondary channel is configured to guide the microspheres released from the other storage tanks into the main channel in an orderly manner.

10. The microsphere encapsulation device according to claim 2, characterized in that, The heat sealing mechanism includes a support base and a test tube holder, a punching female holder, a heat sealing and cutting assembly, and a film conveying assembly, which are respectively disposed on the support base. The test tube holder can be raised and lowered relative to the support seat and is used to support multiple test tubes of the clamping groove group located on the test tube sealing station. The blanking socket is located above the test tube holder, and the blanking socket has a plurality of through holes corresponding to a plurality of test tubes respectively; The heat-sealing cutting assembly is located above the punching female seat and includes a punching plate that can be raised and lowered relative to the support seat and a heat-sealing head disposed on the punching plate. The heat-sealing head is provided with a plurality of heat-sealing ends that correspond to a plurality of through holes respectively. The membrane delivery assembly is configured to deliver the membrane material between the heat sealing head and the punching base.

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