A rotary joint for a cell centrifuge

Abstract

The application discloses a rotary joint for a cell centrifuge and relates to the technical field of cell harvesting equipment.The rotary joint comprises an inner core assembly, a shell, a first horn-shaped sealing ring, a second horn-shaped sealing ring and a magnetic fluid sealing assembly, the inner core assembly is provided with a first channel and a second channel, the shell is sleeved on the outside of the inner core assembly, the inner side wall of the shell is provided with annular first and second flow guide grooves, the first horn-shaped sealing ring is fixed to the inner side wall of the shell and is located on the side of the first flow guide groove away from the second flow guide groove, the small-diameter opening of the first horn-shaped sealing ring is close to the first flow guide groove, the second horn-shaped sealing ring is fixed to the inner side wall of the shell and is located on the side of the second flow guide groove away from the first flow guide groove, and the small-diameter opening of the second horn-shaped sealing ring is close to the second flow guide groove, and the magnetic fluid sealing assembly is arranged between the first and second flow guide grooves.The rotary joint for the cell centrifuge can reduce heat generation during rotation and reduce the influence on cells.

Description

Technical Field

[0001] This invention relates to the field of cell harvesting equipment technology, and in particular to a rotary joint for a cell centrifuge. Background Technology

[0002] Cell therapy refers to the process of introducing human cells, either autologous or allogeneic, into the human body after in vitro manipulation for the treatment of diseases. To ensure therapeutic efficacy, cells are often cultured and concentrated into a single, highly active cell suspension before use.

[0003] The process of concentrating cells into a single cell suspension typically requires the use of a centrifuge. For example, the cell processing method and cell harvesting device disclosed in publication number CN118995576A require the cell sample solution to be pumped into a centrifuge cup. The centrifuge cup needs to rotate, while the tubing connected to it needs to remain stationary. Therefore, a rotary joint is usually installed between the tubing and the centrifuge cup. However, existing rotary joints, to ensure sealing performance, have an interference fit between the rotating inner core and the sealing element. This causes the rotary joint to generate significant heat under prolonged or high-speed rotation. The cell sample solution flowing through the rotary joint is extremely sensitive to temperature; high temperatures can lead to cell inactivation or even death. Currently, to ensure cell viability, cooling time is often added between each step using the centrifuge cup to dissipate heat from the rotary joint. Summary of the Invention

[0004] This invention aims to at least solve one of the technical problems existing in the prior art. To this end, this invention proposes a rotary joint for a cell centrifuge that reduces heat generation during rotation, thereby minimizing the impact on cells.

[0005] A rotary joint for a cell centrifuge according to an embodiment of the present invention includes: an inner core assembly, the inner core assembly having a first channel and a second channel, the inlet of the first channel being opened on the side wall of the inner core assembly, the outlet of the first channel being opened on the end face of the inner core assembly, the inlet of the second channel being opened on the side wall of the inner core assembly, the outlet of the second channel being opened on the end face of the inner core assembly, the inlet of the first channel and the inlet of the second channel being located on different radial planes of the inner core assembly, and the outlet of the first channel and the outlet of the second channel being located on the same end face of the inner core assembly; The outer shell is fitted onto the outside of the inner core assembly. The inner sidewall of the outer shell is provided with an annular first guide groove and an annular second guide groove. The inner core assembly is rotatable around the circumference of the outer shell. The first channel is connected to the first guide groove, and the second channel is connected to the second guide groove. The first horn-shaped sealing ring is fixed to the inner wall of the outer shell, and the inner wall of the first horn-shaped sealing ring is in contact with the outer wall of the inner core assembly. Along the axial direction of the outer shell, the first horn-shaped sealing ring is located on the side of the first guide groove away from the second guide groove, and the small diameter opening of the first horn-shaped sealing ring is close to the first guide groove. The second horn-shaped sealing ring is fixed to the inner wall of the housing, and the inner wall of the second horn-shaped sealing ring contacts the outer wall of the inner core assembly. Along the axial direction of the housing, the second horn-shaped sealing ring is located on the side of the second guide groove away from the first guide groove, and the small diameter opening of the second horn-shaped sealing ring is close to the second guide groove. A magnetic fluid sealing assembly is disposed between the inner core assembly and the outer shell, and along the radial direction of the outer shell, the magnetic fluid sealing assembly is located between the first guide groove and the second guide groove.

[0006] The rotary joint for a cell centrifuge according to an embodiment of the present invention has at least the following beneficial effects: the inner core assembly is used to connect the centrifuge cup of the cell centrifuge, the inner core assembly rotates with the centrifuge cup, and the outer shell is used to connect the pipe; fluid can enter the centrifuge cup through the first guide groove and the first channel, or leave the centrifuge cup from the second channel and the second guide groove; the first horn-shaped sealing ring prevents the fluid in the first guide groove from leaking out. When assembling the rotary joint, the first horn-shaped sealing ring does not need to be interference-fitted with the inner core assembly, but only needs to contact the outer side wall of the inner core assembly. Utilizing the horn-shaped structure, the fluid can contact the outer side wall of the first horn-shaped sealing ring. As the fluid pressure changes, the fluid will squeeze the first horn-shaped sealing ring against the inner core assembly, thereby achieving floating adjustment of the sealing performance. Therefore, better sealing performance can be obtained with minimal friction between the first horn-shaped sealing ring and the inner core assembly. Reducing the friction of the sealing element can reduce rotational heating and reduce the impact on cells.

[0007] According to some embodiments of the present invention, the sidewall of the first guide channel is chamfered, and the fluid in the first guide channel can flow along the chamfer of the first guide channel to contact the outer sidewall of the first horn-shaped sealing ring. The sidewall of the second guide channel is also chamfered, and the fluid in the second guide channel can flow along the chamfer of the second guide channel to contact the outer sidewall of the second horn-shaped sealing ring.

[0008] According to some embodiments of the present invention, the inner core assembly includes a first core and a second core, the first core and the second core are detachably connected, the first core and the second core are axially assembled to form the inner core assembly, the first channel and the second channel are both disposed in the first core, and the second horn-shaped sealing ring is located between the second core and the outer shell.

[0009] According to some embodiments of the present invention, a plurality of connecting bolts are provided between the first core and the second core, the connecting bolts being parallel to the axial direction of the inner core assembly, and the connecting bolts passing through the second core and connecting to the first core.

[0010] According to some embodiments of the present invention, an annular sealing gasket is provided on the end face between the first core and the second core, and the plurality of connecting bolts pass through the inner ring of the sealing gasket.

[0011] According to some embodiments of the present invention, the first core is provided with an annular first mounting groove, the first mounting groove is located on the end face of the first core facing the second core, the sealing gasket is disposed in the first mounting groove, and the thickness of the sealing gasket is greater than the groove depth of the first mounting groove.

[0012] According to some embodiments of the present invention, the second core is provided with an annular second mounting groove, the second mounting groove being located on the end face of the second core facing the first core, along the thickness direction of the sealing gasket, one end of the sealing gasket is embedded in the first mounting groove, and the other end of the sealing gasket is embedded in the second mounting groove.

[0013] According to some embodiments of the present invention, the outlet of the first channel is located at the center of the end face of the inner core assembly, the end of the inner core assembly is provided with a drainage tube, the drainage tube communicates with the first channel, and the drainage tube is coaxially arranged with the inner core assembly.

[0014] According to some embodiments of the present invention, the magnetic fluid sealing assembly includes an annular permanent magnet and multiple annular receiving grooves. The receiving grooves are formed on the inner sidewall of the housing, and the multiple receiving grooves are spaced apart along the axial direction of the housing. The permanent magnet is fixed to the outer sidewall of the inner core assembly. Along the radial direction of the housing, the permanent magnet and the receiving grooves are arranged opposite to each other, and the multiple receiving grooves are filled with magnetic fluid.

[0015] According to some embodiments of the present invention, the end of the inner core assembly is provided with a flange, which is located on the outlet side of the first channel.

[0016] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0017] The present invention will be further described below with reference to the accompanying drawings and embodiments, wherein: Figure 1 This is a first structural cross-sectional view of the rotary joint for a cell centrifuge according to an embodiment of the present invention; Figure 2 This is an enlarged schematic diagram of a portion of the rotary joint structure used in a cell centrifuge according to an embodiment of the present invention; Figure 3 This is a second structural cross-sectional view of the rotary joint for a cell centrifuge according to an embodiment of the present invention; Figure 4 This is a schematic diagram of the rotary joint used in a cell centrifuge according to an embodiment of the present invention.

[0018] Icon labels: Inner core assembly 100, first channel 101, second channel 102, first core 110, first mounting groove 111, second core 120, second mounting groove 121, outer shell 200, first guide groove 201, second guide groove 202, first horn-shaped sealing ring 300, second horn-shaped sealing ring 400, magnetic fluid sealing assembly 500, permanent magnet 510, receiving groove 520, connecting bolt 600, sealing gasket 700, drainage pipe 800, flange 900. Detailed Implementation

[0019] Embodiments of the present invention are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0020] In the description of this invention, it should be understood that the orientation descriptions, such as up, down, etc., are based on the orientation or positional relationship shown in the drawings and are only for the convenience of describing this invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this invention.

[0021] In the description of this invention, "multiple" refers to two or more. The use of "first" and "second" is for distinguishing technical features only and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features or their sequential relationship.

[0022] In the description of this invention, unless otherwise explicitly defined, terms such as "setting," "installing," and "connecting" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this invention in conjunction with the specific content of the technical solution.

[0023] As described in the background section, existing rotary joints, to ensure sealing performance, have an interference fit between the rotating inner core and the sealing element, meaning there is a pre-tightening pressure between the sealing element and the inner core. It's important to understand that when the rotary joint is conveying fluid, the higher the fluid pressure, the greater the pressure between the sealing element and the inner core should be; otherwise, fluid could overflow from between them. Therefore, existing rotary joints, designed for conveying fluids at higher pressures, also have a higher pressure between the sealing element and the inner core. This results in greater friction between the inner core and the sealing element during rotation, leading to more heat generation.

[0024] Reference Figure 1 As shown, a rotary joint for a cell centrifuge according to an embodiment of the present invention includes an inner core assembly 100, a housing 200, a first horn-shaped sealing ring 300, a second horn-shaped sealing ring 400, and a magnetic fluid sealing assembly 500.

[0025] The inner core assembly 100 is provided with a first channel 101 and a second channel 102. The inlet of the first channel 101 is located on the side wall of the inner core assembly 100, and the outlet of the first channel 101 is located on the end face of the inner core assembly 100. The inlet of the second channel 102 is located on the side wall of the inner core assembly 100, and the outlet of the second channel 102 is located on the end face of the inner core assembly 100. The inlets of the first channel 101 and the second channel 102 are located on different radial planes of the inner core assembly 100, and the outlets of the first channel 101 and the second channel 102 are located on the same end face of the inner core assembly 100. The outer shell 200 is fitted onto the outside of the inner core assembly 100. The inner side wall of the outer shell 200 is provided with an annular first guide groove 201 and an annular second guide groove 202. The inner core assembly 100 can rotate around the circumference of the outer shell 200. The first channel 101 communicates with the first guide groove 201, and the second channel 102 communicates with the second guide groove 202. A first trumpet-shaped sealing ring is also provided. The first horn-shaped sealing ring 300 is fixed to the inner wall of the outer casing 200, and the inner wall of the first horn-shaped sealing ring 300 contacts the outer wall of the inner core assembly 100. Along the axial direction of the outer casing 200, the first horn-shaped sealing ring 300 is located on the side of the first guide groove 201 away from the second guide groove 202, and the small diameter opening of the first horn-shaped sealing ring 300 is close to the first guide groove 201; the second horn-shaped sealing ring 400 is fixed to the inner wall of the outer casing 200, and the inner diameter opening of the second horn-shaped sealing ring 400 is close to the outer wall of the inner core assembly 100. The sidewall contacts the outer sidewall of the inner core assembly 100. Along the axial direction of the outer shell 200, the second horn-shaped sealing ring 400 is located on the side of the second guide groove 202 away from the first guide groove 201, and the small diameter opening of the second horn-shaped sealing ring 400 is close to the second guide groove 202; the magnetic fluid sealing assembly 500 is disposed between the inner core assembly 100 and the outer shell 200. Along the radial direction of the outer shell 200, the magnetic fluid sealing assembly 500 is located between the first guide groove 201 and the second guide groove 202.

[0026] The inner core assembly 100 is used to connect to the centrifuge cup of the cell centrifuge. The inner core assembly 100 rotates with the centrifuge cup, and the outer shell 200 is used to connect the tubing. More specifically, the outer shell 200 is provided with a first connector and a second connector. The first connector is connected to the first guide channel 201, and the second connector is connected to the second guide channel 202. The external tubing can be connected to the first connector and the second connector respectively.

[0027] In some embodiments, fluid can enter the centrifuge cup through the first guide groove 201 and the first channel 101, or exit the centrifuge cup through the second channel 102 and the second guide groove 202. The first horn-shaped sealing ring 300 prevents fluid leakage from the first guide groove 201. When assembling the rotary joint, the first horn-shaped sealing ring 300 does not need to be interference-fitted with the inner core assembly 100; it only needs to be in contact with the outer side wall of the inner core assembly 100. That is, there is no need to set a pre-tightening pressure between the first horn-shaped sealing ring 300 and the inner core assembly 100. Utilizing the horn-shaped structure of the first horn-shaped sealing ring 300, the fluid can contact the outer side wall of the first horn-shaped sealing ring 300. As the fluid pressure changes, the fluid will squeeze the first horn-shaped sealing ring 300 against the inner core assembly 100. That is, the clamping force between the first horn-shaped sealing ring 300 and the inner core assembly 100 is dynamically adjusted with the change of fluid pressure, thereby realizing the floating adjustment of the sealing performance of the first horn-shaped sealing ring 300. While ensuring sealing performance, the clamping force between the first horn-shaped sealing ring 300 and the inner core assembly 100 is smaller. Therefore, better sealing performance can be obtained with the minimum friction between the first horn-shaped sealing ring 300 and the inner core assembly 100. Reducing the friction of the sealing element can reduce the rotational heating of the inner core assembly 100 and reduce the impact of heat on the flowing cells.

[0028] Similarly, the second flared sealing ring 400 prevents fluid leakage from the second guide groove 202. When assembling the rotary joint, the second flared sealing ring 400 does not need to be interference-fitted with the inner core assembly 100; it only needs to be in contact with the outer wall of the inner core assembly 100. That is, no pre-tightening pressure is required between the second flared sealing ring 400 and the inner core assembly 100. Utilizing the flared structure of the second flared sealing ring 400, the fluid can contact the outer wall of the second flared sealing ring 400. As the fluid pressure changes, the fluid will squeeze the second flared sealing ring 400 against the inner core assembly 100. Therefore, the clamping force between the second flared sealing ring 400 and the inner core assembly 100 is dynamically adjusted according to the fluid pressure, thereby achieving floating adjustment of the sealing performance of the second flared sealing ring 400. While ensuring sealing performance, the clamping force between the second flared sealing ring 400 and the inner core assembly 100 is smaller. Therefore, better sealing performance can be obtained with the minimum friction between the second flared sealing ring 400 and the inner core assembly 100. Reducing the friction of the sealing element can reduce the rotational heating of the inner core assembly 100 and reduce the impact of heat on the flowing cells.

[0029] The magnetohydrodynamic sealing assembly 500 is located between the first guide channel 201 and the second guide channel 202, and is used to block the fluid in the first guide channel 201 and the second guide channel 202 to prevent the fluids from mixing. The magnetohydrodynamic sealing assembly 500 can also reduce the friction between the inner core assembly 100 and the outer shell 200, thereby reducing heat generation.

[0030] Reference Figure 2 As shown, it can be understood that the side wall of the first guide channel 201 is chamfered, and the fluid in the first guide channel 201 can flow along the chamfer of the first guide channel 201 to contact the outer side wall of the first horn-shaped sealing ring 300. The fluid can squeeze the first horn-shaped sealing ring 300 to adhere to the inner core assembly 100.

[0031] It is understandable that the sidewall of the second guide channel 202 is also chamfered, and the fluid in the second guide channel 202 can flow along the chamfer of the second guide channel 202 to contact the outer sidewall of the second horn-shaped sealing ring 400. The fluid can squeeze the second horn-shaped sealing ring 400 to adhere to the inner core assembly 100.

[0032] When assembling the inner core assembly 100 with the outer casing 200, the inner core assembly 100 needs to be inserted along the axial direction of the outer casing 200. For example... Figure 1 In the structure shown, within the housing 200, the second flared sealing ring 400 is positioned above the first flared sealing ring 300, and the inner core assembly 100 is inserted upwards from the lower end of the housing 200. In this structure, the large-diameter opening of the first flared sealing ring 300 is located below its small-diameter opening. Therefore, the inner core assembly 100 passes through the first flared sealing ring 300 from its large-diameter opening towards its small-diameter opening, conforming to the shape of the first flared sealing ring 300. For the second flared sealing ring 400, its large-diameter opening is located above its small-diameter opening. Therefore, as the inner core assembly 100 continues to be inserted upwards into the housing 200, it first contacts the small-diameter opening of the second flared sealing ring 400, which may push the small-diameter opening of the second flared sealing ring 400 towards its large-diameter opening, potentially damaging the structure of the second flared sealing ring 400.

[0033] Therefore, further optimization is possible. It is understood that the inner core assembly 100 includes a first core 110 and a second core 120. The first core 110 and the second core 120 are detachably connected. The first core 110 and the second core 120 are axially assembled to form the inner core assembly 100. The first channel 101 and the second channel 102 are both disposed in the first core 110. The second horn-shaped sealing ring 400 is located between the second core 120 and the outer shell 200.

[0034] Reference Figure 3In the structure shown, within the outer casing 200, the second flared sealing ring 400 is positioned above the first flared sealing ring 300. The first core 110 is inserted upwards from the lower end of the outer casing 200. In this structure, the large-diameter opening of the first flared sealing ring 300 is located below the small-diameter opening; therefore, the first core 110 passes through the first flared sealing ring 300 from its large-diameter opening towards its small-diameter opening, conforming to the shape of the first flared sealing ring 300. For the second flared sealing ring 400, its large-diameter opening is located above its small-diameter opening; therefore, the second core 120 is inserted downwards from the upper end of the outer casing 200. That is, the second core 120 passes through the second flared sealing ring 400 from its large-diameter opening towards its small-diameter opening, also conforming to the shape of the second flared sealing ring 400. Finally, the first core 110 and the second core 120 are assembled to form the inner core assembly 100.

[0035] It is understood that multiple connecting bolts 600 are provided between the first core 110 and the second core 120. The connecting bolts 600 are parallel to the axial direction of the inner core assembly 100, and the connecting bolts 600 pass through the second core 120 to connect with the first core 110.

[0036] Because the second flared sealing ring 400 contacts the second core 120, the fluid in the second guide groove 202 can enter the splicing gap between the first core 110 and the second core 120. Furthermore, to prevent the connecting bolts 600 from contacting the fluid, it is understood that an annular sealing gasket 700 is provided on the end face between the first core 110 and the second core 120, and multiple connecting bolts 600 pass through the inner ring of the sealing gasket 700.

[0037] The sealing gasket 700 prevents fluid from further entering the inner ring and isolates the fluid from the connecting bolt 600.

[0038] It is understood that the first core 110 is provided with an annular first mounting groove 111, the first mounting groove 111 is located on the end face of the first core 110 facing the second core 120, the sealing gasket 700 is disposed in the first mounting groove 111, and the thickness of the sealing gasket 700 is greater than the groove depth of the first mounting groove 111.

[0039] A sealing gasket 700 is disposed within a first mounting groove 111, which serves to position the sealing gasket 700. The thickness of the sealing gasket 700 is greater than the depth of the first mounting groove 111, ensuring that the sealing gasket 700 can contact the end face of the second core 120 after the first core 110 and the second core 120 are connected. Preferably, the sealing gasket 700 is made of an elastic material, allowing it to be compressed and further improving the sealing effect.

[0040] It is understood that the second core 120 is provided with an annular second mounting groove 121. The second mounting groove 121 is located on the end face of the second core 120 facing the first core 110. Along the thickness direction of the sealing gasket 700, one end of the sealing gasket 700 is embedded in the first mounting groove 111, and the other end of the sealing gasket 700 is embedded in the second mounting groove 121.

[0041] Reference Figure 3 As shown, the sealing gasket 700 is simultaneously embedded in the first mounting groove 111 and the second mounting groove 121, which can further reduce the gap between the first core 110 and the second core 120, while ensuring that the sealing gasket 700 plays a good sealing role.

[0042] It is understood that the outlet of the first channel 101 is located at the center of the end face of the inner core assembly 100, and the end of the inner core assembly 100 is provided with a drainage tube 800, which is connected to the first channel 101 and is coaxially arranged with the inner core assembly 100.

[0043] The drainage tube 800 is used to introduce the fluid from the first channel 101 to the bottom of the centrifuge cup. In some scenarios, the fluid needs to enter the centrifuge cup from the first channel 101, and the upper layer of fluid in the centrifuge cup needs to be discharged from the second channel 102. If the drainage tube 800 is not provided, the fluid enters the centrifuge cup from the outlet of the first channel 101 and easily returns to the outlet of the second channel 102, then returns to the inlet from the outlet of the second channel 102, and is discharged from the second guide channel 202. The fluid stays in the centrifuge cup for a short time, cannot be fully stratified, and reduces the processing effect of the centrifuge cup. The drainage tube 800 is coaxially arranged with the inner core assembly 100. Therefore, when the inner core assembly 100 rotates, the drainage tube 800 will rotate around its own central axis. The drainage tube 800 will not have the effect of stirring the liquid in the centrifuge cup.

[0044] Reference Figure 2 As shown, it can be understood that the magnetic fluid sealing assembly 500 includes an annular permanent magnet 510 and multiple annular receiving grooves 520. The receiving grooves 520 are formed on the inner sidewall of the housing 200. The multiple receiving grooves 520 are spaced apart along the axial direction of the housing 200. The permanent magnet 510 is fixed to the outer sidewall of the inner core assembly 100. Along the radial direction of the housing 200, the permanent magnet 510 and the receiving grooves 520 are arranged opposite to each other. The multiple receiving grooves 520 are all filled with magnetic fluid.

[0045] The magnetofluid, attracted by the permanent magnet 510, can fill the gap between the inner core assembly 100 and the outer shell 200, achieving a sealing effect. At the same time, the frictional resistance between the magnetofluids is small, and the heat generated when the inner core assembly 100 rotates is also small.

[0046] Reference Figure 4As shown, it can be understood that the inner core assembly 100 has a flange 900 at its end, which is located on the outlet side of the first channel 101. The inner core assembly 100 is connected to the centrifuge cup via the flange 900.

[0047] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention.

Claims

1. A rotary joint for a cell centrifuge, characterized in that, include: The inner core assembly (100) is provided with a first channel (101) and a second channel (102). The entrance of the first channel (101) is opened on the side wall of the inner core assembly (100), and the exit of the first channel (101) is opened on the end face of the inner core assembly (100). The entrance of the second channel (102) is opened on the side wall of the inner core assembly (100), and the exit of the second channel (102) is opened on the end face of the inner core assembly (100). The entrances of the first channel (101) and the second channel (102) are located on different radial planes of the inner core assembly (100), and the exits of the first channel (101) and the second channel (102) are located on the same end face of the inner core assembly (100). The outer shell (200) is fitted onto the outside of the inner core assembly (100). The inner sidewall of the outer shell (200) is provided with an annular first guide groove (201) and an annular second guide groove (202). The inner core assembly (100) is rotatable around the outer shell (200). The first channel (101) is connected to the first guide groove (201), and the second channel (102) is connected to the second guide groove (202). A first horn-shaped sealing ring (300) is fixed to the inner wall of the outer shell (200), and the inner wall of the first horn-shaped sealing ring (300) is in contact with the outer wall of the inner core assembly (100). Along the axial direction of the outer shell (200), the first horn-shaped sealing ring (300) is located on the side of the first guide groove (201) away from the second guide groove (202), and the small diameter opening of the first horn-shaped sealing ring (300) is close to the first guide groove (201). The second horn-shaped sealing ring (400) is fixed to the inner wall of the outer shell (200), and the inner wall of the second horn-shaped sealing ring (400) contacts the outer wall of the inner core assembly (100). Along the axial direction of the outer shell (200), the second horn-shaped sealing ring (400) is located on the side of the second guide groove (202) away from the first guide groove (201), and the small diameter opening of the second horn-shaped sealing ring (400) is close to the second guide groove (202). A magnetic fluid sealing assembly (500) is disposed between the inner core assembly (100) and the outer shell (200), and along the radial direction of the outer shell (200), the magnetic fluid sealing assembly (500) is located between the first guide groove (201) and the second guide groove (202).

2. The rotary joint for a cell centrifuge according to claim 1, characterized in that, The sidewall of the first guide channel (201) is chamfered, and the fluid in the first guide channel (201) can flow along the chamfer of the first guide channel (201) to contact the outer sidewall of the first horn-shaped sealing ring (300). The sidewall of the second guide channel (202) is also chamfered, and the fluid in the second guide channel (202) can flow along the chamfer of the second guide channel (202) to contact the outer sidewall of the second horn-shaped sealing ring (400).

3. The rotary joint for a cell centrifuge according to claim 1, characterized in that, The inner core assembly (100) includes a first core (110) and a second core (120). The first core (110) and the second core (120) are detachably connected. The first core (110) and the second core (120) are axially assembled to form the inner core assembly (100). The first channel (101) and the second channel (102) are both disposed in the first core (110). The second horn-shaped sealing ring (400) is located between the second core (120) and the outer shell (200).

4. The rotary joint for a cell centrifuge according to claim 3, characterized in that, A plurality of connecting bolts (600) are provided between the first core (110) and the second core (120). The connecting bolts (600) are parallel to the axial direction of the inner core assembly (100). The connecting bolts (600) pass through the second core (120) and connect to the first core (110).

5. The rotary joint for a cell centrifuge according to claim 4, characterized in that, An annular sealing gasket (700) is provided on the end face between the first core (110) and the second core (120), and a plurality of the connecting bolts (600) pass through the inner ring of the sealing gasket (700).

6. The rotary joint for a cell centrifuge according to claim 5, characterized in that, The first core (110) is provided with an annular first mounting groove (111). The first mounting groove (111) is located on the end face of the first core (110) facing the second core (120). The sealing gasket (700) is disposed in the first mounting groove (111), and the thickness of the sealing gasket (700) is greater than the groove depth of the first mounting groove (111).

7. The rotary joint for a cell centrifuge according to claim 6, characterized in that, The second core (120) is provided with an annular second mounting groove (121). The second mounting groove (121) is located on the end face of the second core (120) facing the first core (110). Along the thickness direction of the sealing gasket (700), one end of the sealing gasket (700) is embedded in the first mounting groove (111), and the other end of the sealing gasket (700) is embedded in the second mounting groove (121).

8. The rotary joint for a cell centrifuge according to claim 1, characterized in that, The outlet of the first channel (101) is located at the center of the end face of the inner core assembly (100). The end of the inner core assembly (100) is provided with a drainage tube (800), which is connected to the first channel (101) and is coaxially arranged with the inner core assembly (100).

9. The rotary joint for a cell centrifuge according to claim 1, characterized in that, The magnetic fluid sealing assembly (500) includes an annular permanent magnet (510) and multiple annular receiving grooves (520). The receiving grooves (520) are formed on the inner sidewall of the outer shell (200). The multiple receiving grooves (520) are spaced apart along the axial direction of the outer shell (200). The permanent magnet (510) is fixed to the outer sidewall of the inner core assembly (100). Along the radial direction of the outer shell (200), the permanent magnet (510) and the receiving grooves (520) are arranged opposite to each other. The multiple receiving grooves (520) are all filled with magnetic fluid.

10. The rotary joint for a cell centrifuge according to claim 1, characterized in that, The inner core assembly (100) is provided with a flange (900) at its end, and the flange (900) is located on the outlet side of the first channel (101).

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