A purslane external composition for improving acne-related skin conditions and use thereof

Abstract

This invention relates to the field of cosmetic technology, and more particularly to a purslane topical composition for improving acne-related skin conditions and its application. The invention provides a purslane topical composition for improving acne-related skin conditions, comprising purslane extract, mung bean sprout extract, and acne care components. These acne care components include five different care pathways, focusing on oil regulation, redness soothing, barrier repair, antioxidant stabilization, and post-acne repair. This topical composition has a scientifically formulated composition that can improve acne-related skin conditions such as excessive sebum secretion, clogged pores, redness and discomfort, fragile skin barrier, recurring breakouts, and uneven skin tone after acne. It offers more comprehensive and targeted efficacy; moreover, the formula is gentle and can be prepared into dosage forms such as gel, serum, lotion, cream, mask, or spray, suitable for daily use by acne sufferers.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, and more particularly to a purslane topical composition for improving acne-related skin conditions and its application. Background Technology

[0002] With the fast pace of modern life, irregular schedules, increased stress, prolonged mask-wearing, incomplete makeup and sunscreen removal, and improper skincare, acne and acne-related skin conditions are becoming increasingly common, representing a growing and prevalent skincare need in the field of functional skincare. Acne-related skin conditions typically involve excessive sebum secretion, clogged pores, disordered keratin metabolism, redness and discomfort, a weakened skin barrier, recurring breakouts, and uneven skin tone and roughness after acne. The skin condition and skincare needs vary significantly among different individuals.

[0003] Currently, acne care products on the market still have many pain points: First, some products rely too much on strong acids, strong exfoliants, or strong oil-controlling ingredients. Although they can improve shine and closed comedones in the short term, they can easily cause dryness, stinging, peeling, and barrier damage. Second, some products only focus on oil control or soothing, and cannot address issues such as redness and discomfort, fragile skin barrier, recurring breakouts, and post-acne repair. Third, some repair products have a thick texture, and long-term use can increase the risk of clogged pores in oily acne-prone skin. Fourth, existing compound formulas lack a clear synergistic logic among components and have failed to form a comprehensive care system that integrates plant-based soothing, oil control and cleansing, barrier repair, antioxidant stabilization, and post-acne repair.

[0004] Purslane is a commonly used plant-based ingredient containing flavonoids, polysaccharides, phenolic acids, and other active substances. When applied topically, it soothes skin discomfort, reduces redness, and enhances skin tolerance. Mung bean sprouts, derived from the germination of mung beans, contain polyphenols, amino acids, polysaccharides, and other small-molecule active substances. After extraction, they can be used as a gentle cleansing and antioxidant care ingredient. Other plant or fungal ingredients such as houttuynia cordata, scutellaria baicalensis, centella asiatica, and inonotus obliquus also have different skincare benefits in topical skincare. Currently, there is no known topical purslane composition that uses purslane extract and mung bean sprout extract as core components and then combines them with different acne care ingredients based on acne-related skin conditions to achieve multi-pathway comprehensive care.

[0005] Therefore, developing a purslane topical composition for improving acne-related skin conditions that is scientifically formulated, has more comprehensive efficacy, is more targeted, is gentle, and is suitable for industrial production has important practical application value.

[0006] While there are existing reports on the use of purslane extract and mung bean sprout extract in combination for skin repair, there is no known acne-related skin condition care composition that uses purslane extract and mung bean sprout extract as essential dual basic components and is modularly combined according to five major acne care pathways: oil regulation, redness soothing, barrier repair, antioxidant stabilization, and post-acne repair. This invention is the first of its kind to propose such a composition. Summary of the Invention

[0007] The purpose of this invention is to provide a purslane topical composition that is scientifically formulated, has more comprehensive efficacy, is more targeted, and is gentle on the skin to improve acne-related skin conditions.

[0008] To achieve the above-mentioned objectives, the present invention provides the following technical solution:

[0009] This invention provides a purslane topical composition for improving acne-related skin conditions. The topical composition comprises the following components in parts by weight: 1.0-8.0 parts of purslane extract, 1.0-8.0 parts of mung bean sprout extract, and acne care components.

[0010] The acne care kit is selected from one of the following groups: Group 1, Group 2, Group 3, Group 4, and Group 5.

[0011] The first group includes: 1.0 to 6.0 parts of houttuynia cordata extract, 1.0 to 5.0 parts of nicotinamide, and one or more of capryloyl glycine, zinc PCA, zinc gluconate, and zinc lactate, and the total amount of these components is 0.1 to 2.0 parts.

[0012] The second group includes: 1.0 to 6.0 parts of Scutellaria baicalensis extract, 0.01 to 0.5 parts of glycyrrhiza chalcone A or glycyrrhiza extract containing glycyrrhiza chalcone A, 0.1 to 1.0 parts of bisabolol, and 0.1 to 0.5 parts of allantoin;

[0013] The third group includes: 1.0-6.0 parts of Centella asiatica extract, 0.1-4.0 parts of ceramide complex lipids, 1.0-5.0 parts of panthenol, and 0.1-1.0 parts of ectoine;

[0014] The fourth group includes: 1.0-3.0 parts of Inonotus obliquus extract, 0.01-0.5 parts of ergothioneine, 1.0-3.0 parts of postbiotic derived from lactic acid bacteria fermentation, and 0.1-1.0 parts of ectoine;

[0015] The fifth group includes: 1.0-6.0 parts of Centella asiatica extract, 1.0-4.0 parts of tranexamic acid, 1.0-5.0 parts of nicotinamide, and 1.0-4.0 parts of N-acetylglucosamine.

[0016] Preferably, the first group also includes 0.5 to 2.0 parts of lactobionic acid.

[0017] Preferably, the first group and / or the second group further include 1.0 to 6.0 parts of witch hazel extract.

[0018] Preferably, the third group also includes 1.0 to 4.0 parts of β-glucan.

[0019] Preferably, the fourth group also includes 1.0 to 6.0 parts of dandelion extract.

[0020] Preferably, the fifth group also includes 1.0 to 5.0 parts of Bletilla striata extract.

[0021] Preferably, the fifth group further includes 0.5 to 2.0 parts of lactobionic acid and / or 0.01 to 0.5 parts of ferulic acid.

[0022] Preferably, the purslane extract and mung bean sprout extract are both present in weight proportions of 2.0 to 6.0 parts.

[0023] Preferably, the pH value of the topical composition is 5.5 to 6.4.

[0024] Preferably, the licorice extract containing glycyrrhizin A has a glycyrrhizin A content of ≥0.5%.

[0025] Preferably, the ceramide complex lipid comprises ceramide, cholesterol, and fatty acids.

[0026] Preferably, the postbiotic source of lactic acid bacteria fermentation includes one or more of the following: lactic acid bacteria fermentation products, lactic acid bacteria fermentation lysate, Bifida ferment lysate, and yeast fermentation product filtrate.

[0027] The present invention also provides a cosmetic kit for improving acne-related skin conditions, comprising at least two of the aforementioned purslane topical compositions, wherein each of the at least two purslane topical compositions contains different acne care components; the dosage form of the purslane topical composition is selected from one or more of gel, serum, lotion, cream, mask, and spray.

[0028] The present invention also provides the use of the purslane topical composition in the preparation of cosmetics for improving acne-related skin conditions.

[0029] Beneficial effects:

[0030] This invention provides a topical purslane composition for improving acne-related skin conditions. It uses purslane extract and mung bean sprout extract as base components, combined with different acne care components, to provide comprehensive care for multiple aspects such as excessive sebum secretion, clogged pores, redness and discomfort, fragile skin barrier, recurring acne breakouts and uneven skin tone after acne, with more comprehensive and targeted effects.

[0031] In this invention, purslane extract and mung bean sprout extract are used as basic soothing and cleansing components. When combined with houttuynia cordata extract, scutellaria baicalensis extract, centella asiatica extract, inoculum birchides extract and other active ingredients, they can form a synergistic effect. Compared with the comparison ratio that lacks purslane extract, mung bean sprout extract or key acne care components, the improvement of related skin indicators is more obvious.

[0032] The experimental results of this invention show that: Example 1 reduced sebum content by 38.6% and closed comedones by 42.3%; Example 2 reduced red area by 46.5% and erythema index by 41.8%; Example 3 reduced TEWL by 35.7% and increased stratum corneum moisture content by 44.2%; Example 4 reduced new acne by 40.8%; and Example 5 reduced red mark area by 39.5% and improved skin tone evenness by 36.2%. These results indicate that the composition of this invention has a good comprehensive improvement effect on acne-related skin conditions.

[0033] The topical composition of this invention has a mild formula that does not contain hormones, antibiotics, animal fats, or strong irritants. Human skin patch tests showed no obvious irritation, making it suitable for daily care of acne-related skin. Detailed Implementation

[0034] This invention provides a topical composition of purslane for improving acne-related skin conditions, the topical composition comprising the following components in parts by weight:

[0035] Purslane extract: 1.0–8.0 parts, preferably 2.0–6.0 parts, more preferably 6 parts;

[0036] The amount of mung bean sprout extract is 1.0 to 8.0 parts, preferably 2.0 to 6.0 parts, and more preferably 4 parts;

[0037] And acne care ingredients.

[0038] In this invention, the acne care component is selected from one of the first group, the second group, the third group, the fourth group, and the fifth group.

[0039] In this invention, the first group comprises: 1.0 to 6.0 parts of houttuynia cordata extract, preferably 2.0 to 4.0 parts, more preferably 3 parts; 1.0 to 5.0 parts of nicotinamide, preferably 2.0 to 4.0 parts, more preferably 3 parts; and one or more of capryloylglycine, zinc PCA, zinc gluconate, and zinc lactate, wherein the total amount is 0.1 to 2.0 parts, preferably 0.3 to 1.2 parts, more preferably 1.1 parts.

[0040] In this invention, the second group comprises: 1.0 to 6.0 parts of Scutellaria baicalensis extract, preferably 2.0 to 4.0 parts, more preferably 3 parts; 0.01 to 0.5 parts of glycyrrhizin A or glycyrrhiza extract containing glycyrrhizin A, preferably 0.05 to 0.4 parts, more preferably 0.3 parts; 0.1 to 1.0 parts of bisabolol, preferably 0.3 to 0.8 parts, more preferably 0.5 parts; and 0.1 to 0.5 parts of allantoin, preferably 0.2 to 0.4 parts, more preferably 0.3 parts.

[0041] In this invention, the third group comprises: 1.0 to 6.0 parts of Centella asiatica extract, preferably 2.0 to 4.0 parts, more preferably 3 parts; 0.1 to 4.0 parts of ceramide complex lipids, preferably 0.3 to 2.0 parts, more preferably 0.8 parts; 1.0 to 5.0 parts of panthenol, preferably 2.0 to 4.0 parts, more preferably 3 parts; and 0.1 to 1.0 parts of ectoine, preferably 0.3 to 0.9 parts, more preferably 0.8 parts.

[0042] In this invention, the fourth group comprises: 1.0 to 3.0 parts of Inonotus obliquus extract, preferably 1.5 to 2.5 parts, more preferably 2 parts; 0.01 to 0.5 parts of ergothioneine, preferably 0.02 to 0.1 parts, more preferably 0.05 parts; 1.0 to 3.0 parts of lactic acid bacteria fermentation-derived postbiotics, preferably 1.5 to 2.5 parts, more preferably 2 parts; and 0.1 to 1.0 parts of ectoine, preferably 0.3 to 0.9 parts, more preferably 0.8 parts.

[0043] In this invention, the fifth group comprises: 1.0 to 6.0 parts of Centella asiatica extract, preferably 2.0 to 4.0 parts, more preferably 3 parts; 1.0 to 4.0 parts of tranexamic acid, preferably 1.5 to 3.0 parts, more preferably 2 parts; 1.0 to 5.0 parts of nicotinamide, preferably 2.0 to 4.0 parts, more preferably 3 parts; and 1.0 to 4.0 parts of N-acetylglucosamine, preferably 1.5 to 3.0 parts, more preferably 2 parts.

[0044] In this invention, the total flavonoid content in purslane extract is preferably ≥1.0%, which can soothe acne-related skin discomfort, improve redness, and enhance skin tolerance, serving as a basic soothing and repairing component; the total polyphenol content in mung bean sprout extract is preferably ≥0.5%, which can provide antioxidant, skin-purifying, and skin-conditioning effects, forming a basic skincare system when combined with purslane extract.

[0045] In this invention, houttuynia cordata extract can help improve excessive sebum secretion and clogged pores; niacinamide can improve sebum secretion, uneven skin tone and rough skin; capryloyl glycine, zinc PCA, zinc gluconate and zinc lactate can regulate sebum secretion and skin microenvironment.

[0046] In this invention, the baicalin content in the Scutellaria baicalensis extract is preferably ≥5.0%, which can improve redness and discomfort related to acne-related skin conditions; glycyrrhizin A or glycyrrhizin extract containing glycyrrhizin A, bisabolol, and allantoin can synergistically soothe skin discomfort and improve local fragility.

[0047] In this invention, Centella asiatica extract can improve acne-related skin conditions such as skin barrier fragility and redness; ceramide complex lipids, panthenol and ectoine can synergistically improve skin barrier condition and reduce dryness, tightness and stinging discomfort.

[0048] In this invention, the polysaccharide content in the Inonotus obliquus extract is preferably ≥10.0%, which can enhance the antioxidant care effect; ergothioneine can improve the antioxidant stabilization ability; lactic acid bacteria fermentation-derived postbiotics can regulate the skin micro-ecological environment; and ectoine can improve the skin's tolerance to external stimuli.

[0049] In this invention, tranexamic acid, niacinamide, and N-acetylglucosamine can improve uneven skin tone, dullness, and roughness after acne-related skin conditions; when further combined with Bletilla striata extract, lactobionic acid, or ferulic acid, it can enhance post-acne repair and skin texture.

[0050] In this invention, the purslane topical composition can be prepared as one or more of the following: gel, serum, lotion, cream, mask, and spray.

[0051] In this invention, the cosmetic excipients acceptable to the product include one or more of the following: water, glycerin, butylene glycol, propylene glycol, carbomer, xanthan gum, sodium hyaluronate, hydroxyethyl cellulose, emulsifier, thickener, preservative, pH adjuster, chelating agent, and oil.

[0052] In this invention, the cosmetic set for improving acne-related skin conditions can be used in stages according to skin condition, or in combination according to daytime and nighttime care needs; for example, the refreshing gel can be used for daytime oil control, the soothing gel can be used for local redness and discomfort care, the barrier repair cream can be used for nighttime repair care, the antioxidant stabilizing essence can be used for daily stabilizing care after staying up late or wearing a mask, and the repair essence can be used for post-acne uneven skin tone and roughness care.

[0053] The technical solutions provided by the present invention will be described in detail below with reference to the embodiments, but they should not be construed as limiting the scope of protection of the present invention.

[0054] Example 1: A refreshing gel for improving acne-related skin condition

[0055] Components (parts by weight): Purslane extract 6 parts, mung bean sprout extract 4 parts, houttuynia cordata extract 3 parts, capryloyl glycine 0.8 parts, zinc PCA 0.3 parts, nicotinamide 3 parts, lactobionic acid 1 part, witch hazel extract 2 parts, glycerin 10 parts, butylene glycol 8 parts, carbomer 0.8 parts, p-hydroxyacetophenone 0.5 parts, 1,2-pentanediol 0.5 parts, arginine 0.4 parts, disodium EDTA 0.05 parts, purified water to 100 parts.

[0056] Preparation method: Add purslane extract, mung bean sprout extract, water-soluble active ingredients, glycerin, and butylene glycol to purified water and stir to dissolve; add carbomer to swell completely, then add p-hydroxyacetophenone, 1,2-pentanediol, and disodium EDTA and mix well; adjust the pH to 5.5-6.4 with arginine, stir to homogenize, and filter to obtain the final product.

[0057] Example 2: A soothing gel for improving acne-related skin condition

[0058] Components (parts by weight): Purslane extract 6 parts, mung bean sprout extract 4 parts, Scutellaria baicalensis extract 3 parts, glycyrrhiza extract containing glycyrrhizin A 0.3 parts, bisabolol 0.5 parts, allantoin 0.3 parts, witch hazel extract 2 parts, glycerin 8 parts, butylene glycol 6 parts, carbomer 0.6 parts, xanthan gum 0.1 parts, p-hydroxyacetophenone 0.5 parts, 1,2-hexanediol 0.5 parts, arginine 0.3 parts, purified water to make up to 100 parts.

[0059] Preparation method: Add water-soluble components to purified water and stir to dissolve. Add carbomer and xanthan gum and let them swell completely. Add p-hydroxyacetophenone and 1,2-hexanediol and mix well. Adjust the pH to 5.5-6.4 with arginine and stir to homogenize.

[0060] Example 3: A barrier-repairing cream for improving acne-related skin condition

[0061] Components (parts by weight): Purslane extract 6 parts, mung bean sprout extract 4 parts, Centella asiatica extract 3 parts, ceramide complex lipid 0.8 parts, panthenol 3 parts, ectoine 0.8 parts, β-glucan 2 parts, glycerin 8 parts, butylene glycol 5 parts, squalane 3 parts, caprylic / capric triglyceride 3 parts, cetearyl alcohol 1 part, emulsifier 2 parts, p-hydroxyacetophenone 0.5 parts, 1,2-pentanediol 0.5 parts, purified water to 100 parts.

[0062] Preparation method: The aqueous phase is heated to 70-80℃ to dissolve the water-soluble components; the oil phase is heated to 70-80℃ to melt the oil and emulsifier; the aqueous phase is added to the oil phase, homogenized at 2000-5000 rpm for 3-10 min, stirred and cooled to below 45℃, the heat-sensitive components are added, the pH is adjusted to 5.5-6.4, and cooled to obtain the final product.

[0063] Example 4: An antioxidant and stabilizing serum for improving acne-related skin condition

[0064] Components (parts by weight): Purslane extract 6 parts, mung bean sprout extract 4 parts, Inonotus obliquus extract 2 parts, ergothioneine 0.05 parts, lactic acid bacteria fermentation product 2 parts, ectoine 0.8 parts, glycerin 8 parts, butylene glycol 6 parts, β-glucan 1 part, xanthan gum 0.2 parts, carbomer 0.4 parts, p-hydroxyacetophenone 0.5 parts, 1,2-hexanediol 0.5 parts, arginine 0.2 parts, purified water to 100 parts.

[0065] Preparation method: Add water-soluble components and thickener to purified water and heat to dissolve. After cooling, add ergothioneine and lactic acid bacteria fermentation products, adjust the pH to 5.5-6.4, and filter to obtain the final product.

[0066] Example 5: A repair serum for improving acne-related skin condition

[0067] Components (parts by weight): Purslane extract 6 parts, mung bean sprout extract 4 parts, Centella asiatica extract 3 parts, tranexamic acid 2 parts, nicotinamide 3 parts, N-acetylglucosamine 2 parts, lactobionic acid 1 part, ferulic acid 0.05 parts, glycerin 8 parts, butylene glycol 6 parts, sodium hyaluronate 0.1 parts, xanthan gum 0.2 parts, carbomer 0.4 parts, p-hydroxyacetophenone 0.5 parts, 1,2-pentanediol 0.5 parts, arginine 0.3 parts, purified water to make up to 100 parts.

[0068] Preparation method: Dissolve the water-soluble component by heating, cool it down and add heat-sensitive components such as ferulic acid, adjust the pH to 5.5-6.4, and filter to obtain the final product.

[0069] Example 6: An oil-free serum gel for improving acne-related skin condition

[0070] Components (parts by weight): 5 parts purslane extract, 5 parts mung bean sprout extract, 2 parts houttuynia cordata extract, 0.5 parts capryloyl glycine, 0.2 parts zinc gluconate, 2 parts nicotinamide, 8 parts glycerin, 6 parts butylene glycol, 0.4 parts hydroxyethyl cellulose, 0.5 parts p-hydroxyacetophenone, 0.5 parts 1,2-hexanediol, and purified water to a total of 100 parts.

[0071] Preparation method: Add each component to purified water in sequence, stir until completely dissolved, and filter to obtain the final product.

[0072] Example 7: A spot gel for improving acne-related skin conditions

[0073] Components (parts by weight): 5 parts purslane extract, 5 parts mung bean sprout extract, 2 parts scutellaria baicalensis extract, 0.2 parts licorice extract containing glycyrrhizin A, 0.3 parts bisabolol, 0.2 parts allantoin, 6 parts glycerin, 4 parts propylene glycol, 0.7 parts carbomer, 0.3 parts arginine, 0.5 parts p-hydroxyacetophenone, and purified water to make up to 100 parts.

[0074] Preparation method: After the carbomer swells, add the water-soluble component, adjust the pH with arginine, and stir until homogeneous.

[0075] Example 8: A soothing and repairing lotion for improving acne-related skin condition

[0076] Components (parts by weight): 5 parts purslane extract, 5 parts mung bean sprout extract, 2 parts centella asiatica extract, 0.5 parts ceramide complex lipids, 2 parts panthenol, 0.5 parts ectoine, 1 part β-glucan, 2 parts squalane, 8 parts glycerin, 1.5 parts emulsifier, and purified water to make up to 100 parts.

[0077] Preparation method: The aqueous phase and oil phase are heated to 70-80℃ respectively, emulsified and homogenized, and the active component is added after cooling. The mixture is then cooled to obtain the final product.

[0078] Example 9: A Balancing Serum for Improving Acne-Related Skin Condition

[0079] Components (parts by weight): 5 parts purslane extract, 5 parts mung bean sprout extract, 1.5 parts birch extract, 0.03 parts ergothioneine, 2 parts bifida ferment lysate, 0.5 parts ectoine, 8 parts glycerin, 1 part light emulsifier, and purified water to make up to 100 parts.

[0080] Preparation method: Prepared by conventional emulsification process, the thermosensitive active ingredient is added after cooling and stirred evenly to obtain the final product.

[0081] Example 10: A repair gel for improving acne-related skin condition

[0082] Components (parts by weight): 5 parts purslane extract, 5 parts mung bean sprout extract, 2 parts centella asiatica extract, 1.5 parts tranexamic acid, 2 parts nicotinamide, 1.5 parts N-acetylglucosamine, 0.8 parts lactobionic acid, 0.03 parts ferulic acid, 8 parts glycerin, 0.2 parts xanthan gum, 1 part light emulsifier, purified water to make up to 100 parts.

[0083] Preparation method: After dissolving in the aqueous phase, emulsify, cool and add the heat-sensitive component, and adjust the pH to the qualified level to obtain the final product.

[0084] Example 11: A serum containing dandelion extract for improving acne-related skin conditions.

[0085] Components (parts by weight): Add 3 parts of dandelion extract to the composition of Example 4, while keeping the other components unchanged.

[0086] Preparation method: Same as in Example 4.

[0087] Example 12: A serum containing Bletilla striata extract for improving acne-related skin conditions.

[0088] Components (parts by weight): Based on Example 5, add 2 parts of Bletilla striata extract, and keep the other components unchanged.

[0089] Preparation method: Same as in Example 5.

[0090] Comparative Example

[0091] Comparative Example 1: Compared with Example 1, no purslane extract was added, and the remaining components were the same as in Example 1.

[0092] Comparative Example 2: Compared with Example 1, no mung bean sprout extract was added, and the remaining components were the same as in Example 1.

[0093] Comparative Example 3: Compared with Example 1, no houttuynia cordata extract was added, and the remaining components were the same as in Example 1.

[0094] Comparative Example 4: Compared with Example 2, no Scutellaria baicalensis extract was added, and the remaining components were the same as in Example 2.

[0095] Comparative Example 5: Compared with Example 2, licorice extract containing glycyrrhizin A was not added, and the remaining components were the same as in Example 2.

[0096] Comparative Example 6: Compared with Example 3, no ceramide complex lipids were added, and the remaining components were the same as in Example 3.

[0097] Comparative Example 7: Compared with Example 4, no ergothioneine was added, and the remaining components were the same as in Example 4.

[0098] Comparative Example 8: Compared with Example 5, no tranexamic acid was added, and the remaining components were the same as in Example 5.

[0099] Comparative Example 9: Compared with Example 5, no N-acetylglucosamine was added, and the remaining components were the same as in Example 5.

[0100] Comparative Example 10: Blank matrix group, which does not contain purslane extract, mung bean sprout extract and acne care components, and the rest of the matrix is ​​the same as the corresponding example.

[0101] Comparative Example 11: Compared with Example 2, no purslane extract or mung bean sprout extract was added, and the remaining components were the same as in Example 2.

[0102] Comparative Example 12: Compared with Example 3, no purslane extract or mung bean sprout extract was added, and the remaining components were the same as in Example 3.

[0103] Comparative Example 13: Compared with Example 4, no purslane extract or mung bean sprout extract was added, and the remaining components were the same as in Example 4.

[0104] Comparative Example 14: Compared with Example 5, no purslane extract or mung bean sprout extract was added, and the remaining components were the same as in Example 5.

[0105] Comparative Example 15: Compared with Example 4, no lactic acid bacteria fermentation products were added, and the remaining components were the same as in Example 4.

[0106] Comparative Example 16: Compared with Example 3, ectoine was not added, and the remaining components were the same as in Example 3.

[0107] Comparative Example 17: Compared with Example 5, no Centella Asiatica extract was added, and the remaining components were the same as in Example 5.

[0108] In the following experimental examples, unless otherwise specified, each experimental example has an independent blank matrix group. The blank matrix group does not contain purslane extract, mung bean sprout extract and acne care components, and the other matrix is ​​the same as the corresponding example.

[0109] Experiment Example 1: In Vitro Rheumatism Evaluation Experiment

[0110] The samples described in Example 2 and Comparative Examples 4 and 5 were used as test substances. A model group, a purslane group, a mung bean sprout group, and a purslane + mung bean sprout group were also set up. A lipopolysaccharide-induced keratinocyte discomfort model was used to detect the relative expression levels of IL-1β, IL-6, IL-8, and TNF-α. Each experiment was repeated three times, and the average value was taken. Statistical analysis was performed using SPSS software. P < 0.05 was considered statistically significant. The results are shown in Table 1.

[0111] Table 1. Results of in vitro soothing evaluation

[0112] Group IL-1β relative expression level / % IL-6 relative expression level / % IL-8 relative expression level / % TNF-α relative expression level / % Model group 100.0±6.5 100.0±7.1 100.0±6.9 100.0±7.4 Purslane group 72.4±5.8* 75.1±6.0* 76.3±5.7* 74.6±6.2* mung bean sprout group 84.5±6.1* 86.2±6.4* 85.7±6.0* 84.9±6.5* Purslane + mung bean sprouts 60.2±4.9** 63.5±5.2** 64.1±5.1** 62.7±5.3** Example 2 group 43.8±4.5**# 45.2±4.8**# 46.1±4.2**# 44.5±4.7**# Comparative Example 4 Groups 58.6±5.1** 60.3±5.5** 61.2±5.4** 59.7±5.2** Comparative Example 5 Groups 56.9±5.0** 59.1±5.3** 60.4±5.0** 58.2±5.1**

[0113] Note: Compared with the model group, *P<0.05, **P<0.01; compared with comparative examples 4 and 5, #P<0.05.

[0114] The results showed that the combination of purslane extract and mung bean sprout extract had a better effect on reducing the expression of inflammatory factors than the single component. In Example 2, the combination of scutellaria baicalensis extract, glycyrrhizin A-related raw materials, bisabolol and allantoin further reduced the expression of inflammatory factors, proving that the composition of the present invention has a good soothing and nursing effect.

[0115] Experiment Example 2: Antioxidant Capacity Evaluation Experiment

[0116] The samples described in Example 4 and Comparative Example 7 were used as test substances. At the same time, mung bean sprout group, birch bark fungus group and ergothioneine group were set up. The antioxidant capacity was evaluated by DPPH, ABTS and cell ROS detection methods. Each group experiment was repeated 3 times and the average value was taken. SPSS software was used for statistical analysis. P<0.05 was considered to be statistically significant. The results are shown in Table 2.

[0117] Table 2. Antioxidant capacity evaluation results

[0118] Group DPPH removal rate / % ABTS clearance rate / % ROS decrease rate / % mung bean sprout group 51.6±4.8* 49.7±4.5* 32.5±3.8* Inonotus obliquus 58.4±5.1* 56.2±5.0* 38.3±4.1* Ergothionein group 62.7±5.4* 60.6±5.2* 42.8±4.5* Example 4 group 81.5±5.6**# 79.2±5.3**# 61.7±5.0**# Comparative Example 7 Groups 63.4±5.2* 61.1±5.0* 43.5±4.4*

[0119] Note: Compared with the mung bean sprout group, *P<0.05, **P<0.01; compared with the comparative example group 7, #P<0.05.

[0120] The results showed that Example 4 had better antioxidant capacity, and ergothioneine had a significant synergistic effect when combined with Inonotus obliquus extract, mung bean sprout extract and other components.

[0121] Experiment Example 3: Evaluation Experiment on Oil Control and Improvement of Closed-up Oil

[0122] Seventy-two subjects with oily, acne-prone skin were randomly divided into four groups: Example 1, Comparative Example 1, Comparative Example 2, Comparative Example 3, and Comparative Example 10, with 12 subjects in each group. Subjects in each group used the corresponding sample continuously for four weeks. The rate of decrease in sebum content, the rate of decrease in the number of closed comedones, and the stimulation score were measured. The results are shown in Table 3.

[0123] Table 3. Effects of Example 1 on oily acne-prone skin and closed comedones.

[0124] Group Sebum content reduction rate / % The rate of decrease in the number of closed comedones / % Stimulation rating / point Example 1 Group 38.6±4.2**# 42.3±5.1**# 0.6±0.2 Comparative Example 1 24.8±3.9* 27.5±4.4* 1.1±0.3 Comparative Example 2 26.1±4.1* 29.2±4.2* 1.0±0.4 Comparative Example 3 Groups 28.4±3.6* 31.6±3.8* 0.9±0.3 Comparative Example 10 6.8±1.9 7.5±2.0 0.5±0.2

[0125] Note: Compared with the control group 10, *P<0.05, P<0.01.

[0126] The results showed that Example 1 could more significantly reduce sebum content and the number of closed comedones, and had a lower irritation score, indicating that there was a synergistic effect between purslane extract, mung bean sprout extract, houttuynia cordata extract and oil-controlling care components.

[0127] Experiment Example 4: Evaluation Experiment on Improvement of Redness and Discomfort

[0128] Seventy-two subjects with acne-related redness and discomfort were randomly divided into four groups: Example 2, Comparative Example 4, Comparative Example 5, Comparative Example 10, and Comparative Example 11, with 12 subjects in each group. Subjects in each group used the corresponding sample continuously for 7 days. The reduction rate of red area, the reduction rate of erythema index, and the burning discomfort score were measured. The results are shown in Table 4.

[0129] Table 4. Effects of Example 2 on improving redness and discomfort.

[0130] Group Red zone area reduction rate / % Erythema index decrease rate / % Burning discomfort rating / point Example 2 group 46.5±5.2**# 41.8±4.6**# 0.5±0.2 Comparative Example 4 Groups 31.2±4.4* 29.6±4.0* 1.0±0.3 Comparative Example 5 Groups 33.8±4.1* 31.4±3.9* 0.9±0.3 Comparative Example 10 8.5±2.1 7.9±1.8 2.3±0.6 Comparative Example 11 36.4±4.5* 33.8±4.1* 0.8±0.3

[0131] Note: Compared with Comparative Example 10, *P<0.05, P<0.01; compared with Comparative Example 11, #P<0.05.

[0132] The results showed that Example 2 had a more significant effect on improving acne-related redness and burning discomfort, and the purslane extract and mung bean sprout extract could further enhance the soothing effect.

[0133] Experiment Example 5: Barrier Repair Evaluation Experiment

[0134] Seventy-five subjects with dry, sensitive, and acne-prone skin were randomly divided into four groups: Example 3, Comparative Example 6, Comparative Example 10, Comparative Example 12, and Comparative Example 16, with 12-13 subjects in each group. Subjects in each group used the corresponding sample continuously for four weeks. The TEWL decrease rate, stratum corneum moisture content increase rate, and stinging score were measured. The results are shown in Table 5.

[0135] Table 5. Improvement effect of Example 3 on barrier status

[0136] Group TEWL decline rate / % stratum corneum moisture content increase rate / % Stinging Score / points Example 3 Group 35.7±4.3**# 44.2±5.1**# 0.4±0.1 Comparative Example 6 Groups 22.4±3.8* 28.6±4.2* 0.9±0.3 Comparative Example 10 5.6±1.5 6.8±1.7 1.9±0.5 Comparative Example 12 28.1±4.0* 34.2±4.5* 0.8±0.2 Comparative Example 16 27.5±3.9* 33.4±4.2* 1.0±0.3

[0137] Note: Compared with Comparative Example 10, *P<0.05, P<0.01; compared with Comparative Example 12, #P<0.05.

[0138] The results showed that Example 3 could improve the barrier state, reduce transepidermal water loss and increase the stratum corneum moisture content.

[0139] Experiment Example 6: Evaluation of Recurrent Acne Breakouts and Stabilization

[0140] Seventy-five subjects who experienced recurrent acne breakouts or were prone to acne after staying up late were randomly divided into four groups: Example 4, Comparative 7, Comparative 10, Comparative 13, and Comparative 15, with 12-13 subjects in each group. Subjects in each group used the corresponding sample continuously for four weeks. The rate of decrease in new acne breakouts, redness score after wearing a mask, and skin stability score were recorded. The results are shown in Table 6.

[0141] Table 6. Effects of Example 4 on improving recurrent acne breakouts and stabilization of acne.

[0142] Group The rate of decrease in the number of new pimples / % Mask turns red after being stuffy / points Skin stability score / points Example 4 group 40.8±4.9**# 0.7±0.2 8.8±0.6**# Comparative Example 7 Groups 25.3±3.7* 1.3±0.3 7.1±0.5* Comparative Example 10 6.2±1.9 2.5±0.5 5.2±0.7 Comparative Example 13 31.5±4.1* 1.1±0.3 7.5±0.5* Comparative Example 15 30.8±4.0* 1.2±0.3 7.3±0.6*

[0143] Note: Compared with Comparative Example 10, *P<0.05, P<0.01; compared with Comparative Example 13, #P<0.05.

[0144] The results showed that Example 4 could reduce recurring acne breakouts, improve redness and discomfort caused by wearing a mask, and enhance skin stability.

[0145] Experiment Example 7: Evaluation of Uneven Skin Tone and Roughness After Acne

[0146] Seventy-two subjects with post-acne redness, acne scars, dullness, or roughness were randomly divided into four groups: Example 5, Comparative Example 8, Comparative Example 9, Comparative Example 10, Comparative Example 14, and Comparative Example 17, with 10-11 subjects in each group. Subjects in each group used the corresponding sample continuously for 8 weeks. The reduction rate of post-acne redness area, the improvement rate of skin tone evenness, and the reduction rate of roughness were measured. The results are shown in Table 7.

[0147] Table 7. Effects of Example 5 on improving uneven skin tone and roughness after acne.

[0148] Group Red-printed area decrease rate / % Skin tone evenness improvement rate / % Roughness reduction rate / % Example 5 group 39.5±4.8**# 36.2±4.1**# 33.8±3.9**# Comparative Example 8 Groups 25.4±3.6* 24.3±3.5* 25.7±3.2* Comparative Example 9 Groups 27.1±3.9* 25.6±3.8* 26.4±3.4* Comparative Example 10 7.4±1.8 6.9±1.5 8.1±1.9 Comparative Example 14 29.3±3.8* 28.1±3.7* 27.6±3.5* Comparative Example 17 28.7±3.7* 27.4±3.6* 25.9±3.4*

[0149] Note: Compared with Comparative Example 10, *P<0.05, P<0.01; compared with Comparative Example 14, #P<0.05.

[0150] The results showed that Example 5 could improve post-acne redness, uneven skin tone, and roughness.

[0151] Experimental Example 8: Human Skin Patch Test

[0152] Thirty healthy subjects were selected. A closed patch test method was used. The samples of Examples 1 to 5 were applied to the patch applicator and then applied to the skin on the back of the subjects. The patch applicator was removed after 24 hours. Skin reactions were observed at 0.5 hours, 24 hours and 48 hours after removal. Reactions such as erythema, edema, papules, vesicles, stinging and itching were evaluated. The results are shown in Table 8.

[0153] Table 8 Results of human skin patch tests in Examples 1-5

[0154] sample Number of subjects Number of negative cases Number of people with mild erythema Significantly stimulated the number of people Evaluation results Example 1 30 29 1 0 No obvious stimulation Example 2 30 30 0 0 No obvious stimulation Example 3 30 30 0 0 No obvious stimulation Example 4 30 30 0 0 No obvious stimulation Example 5 30 29 1 0 No obvious stimulation

[0155] The results showed that no obvious irritation was observed in the topical compositions of Examples 1-5, indicating that the compositions of the present invention are mild and suitable for daily care of acne-related skin.

[0156] Experimental Example 9: Long-term stability test of the product

[0157] The products obtained in Examples 1 to 5 were stored continuously for 36 months at a temperature of 25℃±2℃ and a relative humidity of 60%±5%. The appearance, odor, pH, retention rate of the main active ingredients and microbial limit of the products were tested at 0 months, 6 months, 12 months, 24 months and 36 months to verify the stability of the products. The results are shown in Table 9.

[0158] In Example 1, the main active ingredient content was measured using total flavonoids, nicotinamide, and zinc from purslane; in Example 2, the main active ingredient content was measured using total flavonoids, baicalin, and bisabolol from purslane; in Example 3, the main active ingredient content was measured using total flavonoids, panthenol, and ceramide complex lipids from purslane; in Example 4, the main active ingredient content was measured using total flavonoids from purslane, ergothioneine, and Inonotus obliquus polysaccharide; and in Example 5, the main active ingredient content was measured using total flavonoids from purslane, nicotinamide, tranexamic acid, and N-acetylglucosamine.

[0159] Table 9 Results of Long-Term Stability Tests for Products

[0160] sample Detection time Retention rate of main active ingredients / % pH range Appearance and condition Microbial limits Example 1: Refreshing Gel 0 months 100.0 5.9 The gel is uniform and smooth, without layering or odor. Meets requirements Example 1: Refreshing Gel 36 months 92.6 5.8～6.1 The gel is uniform, without layering, obvious discoloration, or odor. Meets requirements Example 2: Soothing Curd 0 months 100.0 5.9 The curd is smooth and uniform, without layering or off-odors. Meets requirements Example 2: Soothing Gel 36 months 93.4 5.7～6.1 The curd is uniform, without layering, obvious discoloration, or off-odor. Meets requirements Example 3 Barrier Repair Cream 0 months 100.0 6.0 The cream is smooth and even, with no oil-water separation. Meets requirements Example 3 Barrier Repair Cream 36 months 94.1 5.8～6.2 The cream is smooth and even, with no oil-water separation and no odor. Meets requirements Example 4: Antioxidant and Stabilizing Essence 0 months 100.0 5.9 The serum is evenly clear or slightly cloudy, without any sediment. Meets requirements Example 4: Antioxidant and Stabilizing Essence 36 months 91.8 5.7～6.1 The serum is stable, with no obvious sediment or odor. Meets requirements Example 5 Repairing Essence 0 months 100.0 5.9 The serum is evenly distributed and smooth, with no sediment or odor. Meets requirements Example 5 Repairing Essence 36 months 92.2 5.8～6.2 The serum remained stable, with no noticeable discoloration, sedimentation, or odor. Meets requirements

[0161] Note: The retention rate of the main active ingredients is a comprehensive evaluation result of the retention rates of the main active indicators mentioned above in the corresponding samples.

[0162] The microbial limit "meets the requirements" means that the total number of colonies is <10 CFU / g, the total number of molds and yeasts is <10 CFU / g, and thermotolerant coliforms, Staphylococcus aureus, and Pseudomonas aeruginosa are not detected.

[0163] The results showed that the dosage forms containing the composition of the present invention, such as gels, creams, and serums, all had a retention rate of ≥90% of the main active ingredients during the 36-month long-term stability study. The appearance, odor, pH, and microbial limits all met the relevant quality requirements for cosmetics, indicating that the composition of the present invention has good long-term stability and is suitable for industrial production and market circulation.

[0164] As can be seen from the above embodiments, the present invention provides a purslane topical composition for improving acne-related skin conditions and its application. This topical composition uses purslane extract and mung bean sprout extract as base components, combined with different acne care components, resulting in a scientifically formulated, more comprehensive, and more targeted effect. It can improve acne-related skin conditions such as excessive sebum secretion, clogged pores, redness and discomfort, fragile skin barrier, recurring breakouts, and uneven skin tone after acne. Simultaneously, this topical composition is gentle, has a wide range of formulation compatibility, and excellent long-term stability, making it suitable for daily use by acne sufferers.

[0165] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A purslane external composition for improving a skin condition associated with acne, characterized in that, It includes the following components in parts by weight: purslane extract 1.0 to 8.0 parts, mung bean sprout extract 1.0 to 8.0 parts, and acne care components; The acne care kit is selected from one of the following groups: Group 1, Group 2, Group 3, Group 4, and Group 5. The first group includes: 1.0 to 6.0 parts of houttuynia cordata extract, 1.0 to 5.0 parts of nicotinamide, and one or more of capryloyl glycine, zinc PCA, zinc gluconate, and zinc lactate, and the total amount of these components is 0.1 to 2.0 parts. The second group includes: 1.0 to 6.0 parts of Scutellaria baicalensis extract, 0.01 to 0.5 parts of glycyrrhiza chalcone A or glycyrrhiza extract containing glycyrrhiza chalcone A, 0.1 to 1.0 parts of bisabolol, and 0.1 to 0.5 parts of allantoin; The third group includes: 1.0-6.0 parts of Centella asiatica extract, 0.1-4.0 parts of ceramide complex lipids, 1.0-5.0 parts of panthenol, and 0.1-1.0 parts of ectoine; The fourth group includes: 1.0-3.0 parts of Inonotus obliquus extract, 0.01-0.5 parts of ergothioneine, 1.0-3.0 parts of postbiotic derived from lactic acid bacteria fermentation, and 0.1-1.0 parts of ectoine; The fifth group includes: 1.0-6.0 parts of Centella asiatica extract, 1.0-4.0 parts of tranexamic acid, 1.0-5.0 parts of nicotinamide, and 1.0-4.0 parts of N-acetylglucosamine.

2. The Portulaca oleracea external composition according to claim 1, characterized by, The first group also includes 0.5 to 2.0 parts of lactobionic acid.

3. The Portulaca oleracea external composition according to claim 1, characterized by, The first group and / or the second group also include 1.0 to 6.0 parts of witch hazel extract.

4. The Portulaca oleracea external composition according to claim 1, characterized by, The third group also includes 1.0 to 4.0 parts of β-glucan.

5. The Portulaca oleracea external composition according to claim 1, characterized by, The fourth group also includes 1.0 to 6.0 parts of dandelion extract.

6. The Portulaca oleracea external composition according to claim 1, characterized by, The fifth group also includes one or more of the following: Bletilla striata extract (1.0-5.0 parts), lactobionic acid (0.5-2.0 parts), and ferulic acid (0.01-0.5 parts).

7. The Portulaca oleracea external composition according to any one of claims 1 to 6, characterized by, The purslane extract and mung bean sprout extract are both present in weight fractions of 2.0 to 6.0 parts.

8. The Portulaca oleracea external composition according to any one of claims 1 to 7, characterized by, The pH value of the topical composition is 5.5 to 6.

4.

9. The purslane topical composition according to any one of claims 1 to 8, characterized in that, The ceramide complex lipids include ceramides, cholesterol, and fatty acids; the lactic acid bacteria fermentation-derived postbiotics include one or more of lactic acid bacteria fermentation products, lactic acid bacteria fermentation lysates, Bifida ferment lysate, and yeast fermentation product filtrate; the licorice extract containing glycyrrhizin A has a glycyrrhizin A content ≥0.5%.

10. A cosmetic set for improving the state of acne-related skin, characterized by, The product comprises at least two purslane topical compositions as described in any one of claims 1 to 9, wherein the at least two purslane topical compositions each contain different acne care components; the dosage form of the purslane topical composition is selected from one or more of gel, serum, lotion, cream, mask, and spray.

11. The use of the purslane topical composition according to any one of claims 1 to 9 in the preparation of cosmetics for improving acne-related skin conditions.